In this consensus report by a diverse group of academics who conduct and/or are concerned about social and behavioral genomics (SBG) research, the authors recount the often‐ugly history of scientific attempts to understand the genetic contributions to human behaviors and social outcomes. They then describe what the current science—including genomewide association studies and polygenic indexes—can and cannot tell us, as well as its risks and potential benefits. They conclude with a discussion of responsible behavior in the context of SBG research. (...) SBG research that compares individuals within a group according to a “sensitive” phenotype requires extra attention to responsible conduct and to responsible communication about the research and its findings. SBG research (1) on sensitive phenotypes that (2) compares two or more groups defined by (a) race, (b) ethnicity, or (c) genetic ancestry (where genetic ancestry could easily be misunderstood as race or ethnicity) requires a compelling justification to be conducted, funded, or published. All authors agree that this justification at least requires a convincing argument that a study's design could yield scientifically valid results; some authors would additionally require the study to have a socially favorable risk‐benefit profile. (shrink)

When a physician employment relationship terminates, the physician–patient relationship may also be terminated by enforcement of a covenant not to compete, which typically forces the physician to leave the geographic area for a period of time. This gives rise to several ethical dilemmas. The public interest is compromised when enforcement of these covenants contributes to the shortage of physicians in the community, and individual patients are harmed when their physicians are no longer available. The authors undertook a unique study to (...) explore physician perspectives concerning the ethics of banning a physician from practice and the impact of the ban on both the physician and the physician’s patients. The results identified harmful effects that have not been raised in prior scholarly articles or reported court opinions. After reviewing the legal background of covenants not to compete, this paper presents the results of that study and concludes that resorting to the legal system for enforcement of covenants not to compete is not always the ethical course of action. (shrink)

Bioethicists frequently call for empirical researchers to engage participants and community members in their research, but don't themselves typically engage community members in their normative research. In this article, we describe an effort to include members of the public in normative discussions about the risks, potential benefits, and ethical responsibilities of social and behavioral genomics (SBG) research. We reflect on what might—and might not— be gained from engaging the public in normative scholarship and on lessons learned about public perspectives on (...) the risks and potential benefits of SBG research and the responsible conduct and communication of such research. We also provide procedural lessons for others in bioethics who are interested in engaging members of the public in their research. (shrink)

BackgroundInformation processing speed is a marker for cognitive function. It is associated with neural maturation and increases during development. Traditionally, IPS is measured using paper and pencil tasks requiring fine motor skills. Such skills are often impaired in patients with neurological conditions. Therefore, an alternative that does not need motor dexterity is desirable. One option is the computerized symbol digit modalities test, which requires the patient to verbally associate numbers with symbols.MethodsEighty-six participants were examined, 38 healthy and 48 hospitalized for (...) a non-neurological disease. All participants performed the written SDMT, c-SDMT, and the Test of Non-verbal Intelligence Fourth Edition. Statistical analyses included a multivariate analysis of covariance for the effects of intelligence and hospitalization on the performance of the SDMT and c-SDMT. A repeated measures analysis of variance was used to compare performance across c-SDMT trials between inpatients and outpatients.ResultsThe MANCOVA showed that hospitalization had a significant effect on IPS when measured with the SDMT but not with the c-SDMT, while IQ had no effect on IPS. Age was the best predictor of performance of both tests. The repeated measures ANOVA revealed no significant difference in within-test performance between outpatient and inpatient participants in the c-SDMT.ConclusionPerformance of the c-SDMT is not confounded by hospitalization and gives within-test information. As a valid and reliable measure of IPS for children and adolescents, it is suitable for use in both inpatient and outpatient populations. (shrink)

AimRapid eye movement (REM) sleep, non-rapid eye movement (NREM) sleep, and sleep spindles are all implicated in the consolidation of procedural memories. Relative contributions of sleep stages and sleep spindles were previously shown to depend on individual differences in task processing. However, no studies to our knowledge have focused on individual differences in experience with Vipassana meditation as related to sleep. Vipassana meditation is a form of mental training that enhances proprioceptive and somatic awareness and alters attentional style. The goal (...) of this study was to examine a potential role for Vipassana meditation experience in sleep-dependent procedural memory consolidation.MethodsGroups of Vipassana meditation practitioners (N = 22) and matched meditation-naïve controls (N = 20) slept for a daytime nap in the laboratory. Before and after the nap they completed a procedural task on the Wii Fit balance platform.ResultsMeditators performed slightly better on the task before the nap, but the two groups improved similarly after sleep. The groups showed different patterns of sleep-dependent procedural memory consolidation: in meditators, task learning was positively correlated with density of slow occipital spindles, while in controls task improvement was positively associated with time in REM sleep. Sleep efficiency and sleep architecture did not differ between groups. Meditation practitioners, however, had a lower density of occipital slow sleep spindles tha... (shrink)

ObjectiveThe objective of this study was to validate the computerized Symbol Digit Modalities Test in a Swiss pediatric cohort, in comparing the Swiss sample to the Canadian norms. Secondly, we evaluated sex effects, age-effects, and test–retest reliability of the c-SDMT in comparison to values obtained for the paper and pencil version of the Symbol Digit Modalities Test.MethodsThis longitudinal observational study was conducted in a single-center setting at the University Children’s Hospital of Bern. Our cohort consisted of 86 children aged from (...) 8 to 16 years. The cohort included both healthy participants and patients hospitalized for a non-neurological disease. Forty eight participants were assessed during two testing sessions with the SDMT and the c-SDMT.ResultsTest–retest reliability was high in both tests. A reliable change index was calculated for the SDMT and the c-SDMT corrected for practice effects. While a significant age effect on information processing speed was observed, no such effect was found for sex. When data on the c-SDMT performance of the Swiss cohort was compared with that from a Canadian cohort, no significant difference was found for the mean time per trial in any age group. Norm values for age groups between 8 and 16 years in the Swiss cohort were established.ConclusionNorms for the c-SDMT between the Swiss and the Canadian cohort were comparable. The c-SDMT is a valid alternative to the SDMT. It is a feasible and easy to administer bedside tool due to high reliability and the lack of motor demands. (shrink)

Attraper erôs dans le filet du logos, l'Occident n'a pas attendu la psychanalyse pour s'y employer. Entre [es aphrodisia grecs et le dispositif de sexualité moderne, il ne restait plus à Foucault qu'à déposer une dernière pièce au puzzle de son Histoire de la sexualité : que s'est-il passé au temps de la concupiscence chrétienne et du péché de chair? Comment le sexe en est-il venu à polariser le rapport de soi à soi? 'Il m'a semblé, écrit Foucault, que la (...) question qui devait servir de fil directeur était celle-ci : comment, pourquoi et sous quelle forme ['activité sexuelle a-t-elle été constituée comme domaine moral?' À qui sont destinés les aveux? De quoi libèrent-ils? Quel sujet moderne l'expérience de la 'chair' dans le christianisme a-t-elle contribué à construire? Les Aveux de la chair jettent le trouble dans une 'histoire de la sexualité' qui s'avère faussement linéaire et sollicite tout autant philosophes, historiens, spécialistes de la littérature et psychanalystes. Ce volume fait écho à Bien avant la sexualité. L'expérience érotique en Grèce ancienne, publié en 2019 chez Epel."--Page 4 of cover. (shrink)

La revue Genesis, notre sœur latine, a publié en 2006 un numéro consacré aux « Objets ». Sandra Cavallo et Isabelle Chabot qui ont coordonné le numéro, présentent dans une copieuse introduction la généalogie de ce numéro à partir de l’intérêt porté à la culture matérielle des classes subalternes – en particulier du monde paysan –, puis de l’attention portée à la consommation chez les élites florentines du Rinascimento (xive-xve siècle). Dans un premier temps les études ont concerné la (...) famille... (shrink)

Tomando como ponto de partida os trabalhos de Nietzsche, Hannah Arendt e Michel Foucault, este escrito pretende problematizar a lógica interna da compaixão piedosa, pois, como tentaremos mostrar, ela parece instaurar uma modalidade peculiar de exercício de poder que se estrutura a partir do binômio servir-obedecer. A partir desses autores, pretendemos ler alguns exemplos que a história da humanidade nos apresenta para ilustrar o exercí- cio dessa “cruel compaixão”.

Taking the works of Nietzsche, Arendt and Foucault as starting point, we analyze the endogenous logic to the notion of pitiful compassion which instrumentalists a peculiar form of power captured by the duality serve-obey. From the perspective of this authors, we provide examples that history presented to illustrate the deployment of "cruel compassion".Tomando como ponto de partida os trabalhos de Nietzsche, Hannah Arendt e Michel Foucault, este escrito pretende problematizar a lógica interna da compaixão piedosa, pois, como tentaremos mostrar, (...) ela parece instaurar uma modalidade peculiar de exercício de poder que se estrutura a partir do binômio servir-obedecer. A partir desses autores, pretendemos ler alguns exemplos que a história da humanidade nos apresenta para ilustrar o exercício dessa "cruel compaixão". (shrink)

This volume, published for the first time in English, takes an interdisciplinary approach to exploring how the work of Michel Foucault has influenced studies of Ancient Greece and Rome. Of interest to students and scholars in classical studies, philosophy, gender studies, and ancient history.

_John Dewey and Continental Philosophy_ provides a rich sampling of exchanges that could have taken place long ago between the traditions of American pragmatism and continental philosophy had the lines of communication been more open between Dewey and his European contemporaries. Since they were not, Paul Fairfield and thirteen of his colleagues seek to remedy the situation by bringing the philosophy of Dewey into conversation with several currents in continental philosophical thought, from post-Kantian idealism and the work of Friedrich Nietzsche (...) to twentieth-century phenomenology, hermeneutics, and poststructuralism. This unique volume includes discussions comparing and contrasting Dewey with the German philosophers G. W. F. Hegel, Friedrich Nietzsche, Martin Heidegger, and Hans-Georg Gadamer on such topics as phenomenology, naturalism, organicism, contextualism, and poetry. Others investigate a series of connections between Dewey and contemporary French philosophy, including the notions of subjectivity, education, and the critique of modernity in Michel Foucault; language and politics in Jacques Derrida; and the concept of experience in Gilles Deleuze. Also discussed is the question of whether we can identify traces of _Bildung_ in Dewey’s writings on education, and pragmatism’s complex relation to twentieth-century phenomenology and hermeneutics, including the problematic question of whether Heidegger was a pragmatist in any meaningful sense. Presented in intriguing pairings, these thirteen essays offer different approaches to the material that will leave readers with much to deliberate. _ John Dewey and Continental Philosophy_ demonstrates some of the many connections and opportunities for cross-traditional thinking that have long existed between Dewey and continental thought, but have been under-explored. The intersection presented here between Dewey’s pragmatism and the European traditions makes a significant contribution to continental and American philosophy and will spur new and important developments in the American philosophical debate. (shrink)

Este artigo discute, de forma interdisciplinar, como é possível, em um Estado Democrático de Direito, existir formas de vida expostas às mais diversas possibilidades de violações de direitos e garantias fundamentais, como as das pessoas em situação de rua no Brasil. O objetivo deste artigo é mostrar como se deu o início do problema das pessoas em situação de rua no país e como o Estado brasileiro enxerga a questão, e a partir disso refletir como o acesso a direitos impede (...) que estes indivíduos detenham participação na sociedade. Assim, se tratará a hipótese de que as pessoas em situação de rua, do ponto de vista do Estado, por não habitarem o contexto político, econômico e social de forma efetiva não são tratados como seres sujeitos de direitos na ordem pública, o que legitima tomada de decisões que são, em parte, danosas a esta classe e cobertas por um véu falacioso de cuidado com este contingente populacional. Para sustentar e desenvolver este artigo foi utilizada uma metodologia de pesquisa que analisa como se deu a formação da questão no contexto sócio político brasileiro, bem como uma abordagem crítica das bases normativas instituídas em torno da problemática. Ainda, se utilizou das contribuições bibliográficas de autores que escrevem sobre: politização da vida, poder estatal e relações sociais, tais como Michel Foucault, Giorgio Agamben e Achille Mbembe. (shrink)

This volume is a wonderful introduction to Foucault and a testimony to the deep humanity of the man himself.

Moral psychology studies the features of cognition, judgement, perception and emotion that make human beings capable of moral action. Perspectives from feminist and race theory immensely enrich moral psychology. Writers who take these perspectives ask questions about mind, feeling, and action in contexts of social difference and unequal power and opportunity. These essays by a distinguished international cast of philosophers explore moral psychology as it connects to social life, scientific studies, and literature.

Este artículo intenta poner en evidencia que en el pensamiento de Emmanuel Lévinas la justicia es la condición necesaria de apertura -y disolución- del "yo" que hace posible la fecundidad -la "procreación"-, y que en esa misma medida el Logos se transforme en un "quiere decir" y el mundo en un "entre-nosotros". Asimismo, evidencia que esta noción de justicia está directamente vinculada a las ideas de "expresión" y "desnudez", gracias a las cuales el Otro se impone ante el "mismo" como (...) hombre, singular y vulnerable; y que en igual medida está enlazada a la noción de rostro y a su modo particular de manifestación. Proponemos, en este sentido, que la justicia, en tanto que condición necesaria puede fundar un mundo constituido éticamente, en el que prime un "orden erótico" por sobre los ordenamientos lógicos. This paper attempts to demonstrate that in Emmanuel Lévinas' thinking, justice is the necessary opening - and dissolution- of the "I" which makes fecundity - procreation - possible, and that in that same measure makes possible that the Logos transforms into a "desire to say" and the world into a "among us". At the same time it wants to demonstrate that this notion ofjustice is directly related to the ideas of expression and nudity. Due to which the "Other" imposes itself in front of the "same", as man, singular and vulnerable, and that in the same measure it is linked to the notion of the Face and its particular mode of manifestation. In this respect, we propose that justice. As long as necessary condition, can fund an ethically constituted world, where an "erotic order" mandates over logic orderings. (shrink)

El objetivo de este artículo es indagar acerca de la noción de “pasividad” que caracteriza al sujeto en el proyecto ético de Emmanuel Levinas. Un sujeto que es y está entregado al Otro, más allá de toda decisión voluntaria y de cualquier relación fáctica. La “pasividad” es la noción que permite comprender la contextura de la subjetividad levinasiana, su modo de constituirse, de “realizarse”, así como algo que denominaremos su “condición segunda”. La pasividad aparece en el pensamiento de Levinas como (...) la noción que le permite articular su ética, en tanto que ésta se funda en una responsabilidad que acontece en el extremo abandono de las certidumbres del “si mismo”, del “yo”. (shrink)

Este artículo se propone indagar acerca de la distinción entre el Decir y lo Dicho en la obra de Emmanuel Levinas. Esta distinción sirve a Levinas para proponer una comprensión ética del lenguaje, en la que la significación y la expresión sean capaces de superar las limitaciones y determinaciones del lenguaje sistemático de la ontología, del ser y las esencias. Sobre la base de que el “lenguaje de la ontología” es impertinente para comprender, expresar o comunicar esa “experiencia ética” fundamental (...) del encuentro “cara a cara” con el Rostro del Otro: la experiencia misma de la significancia misma, Levinas propone una comprensión pre-ontológica del lenguaje. Esta comprensión pre-ontológica sería capaz de dar respuesta a las siguientes preguntas: ¿Cuál es el lenguaje, la palabra propia, de ese sujeto pasivo, de ese sujeto que es rehén del Otro , que está sujeto a él? ¿Cuál es el lenguaje del dar-se, qué palabra puede hacerse cargo de lo que es siempre in-apropiable? ¿Cómo será ese lenguaje que intenta decir lo otro del ser, ese lenguaje capaz de “traducir” la significancia que se da en la experiencia ética originaria, aquella en la que la “unicidad insustituible de una persona se expone a otra persona”? En este sentido, proponemos que el Decir es, con respecto a lo dicho, su tener-lugar, la posibilidad misma de comunicación y expresión, en la que se expone la condición pasiva del sujeto. Por otra parte, en la medida en que el Decir es la expresión de la significancia que adviene en la proximidad con el Otro, el Decir es siempre testimonial.This text proposes an inquiry regarding the distinction between the Saying and the Said in Emmanuel Levinas works. Levinas uses this distinction to propose an ethical understanding of language, where significance and expression are capable of overcoming the limitations of ontology`s systematic language, of the being, and the essences. On the basis of that “the language of ontology” is impertinent to understand, express, or communicate this “ethical experience” fundamental for the “face to face encounter” with the Face of the Other: the experience of significance itself, Levinas proposes a pre-ontologic understanding of language. This pre-ontologic understanding would be capable of answering the following questions: What is the language, the word itself of that passive subject, that subject who is a hostage of the Other who is attached to him? Which is the language of giving oneself, which word can take charge of what is always non appropriable? What kind of language will it be that tries to say the other of the being, that language able to “translate” the significance given in the original ethical experience, that where the “irreplaceable uniqueness of a person is being exposed to another person”? In this respect, we propose that the Saying is, regarding the said, its having-occurred, the possibility itself of communicating and expressing, where the passive condition of the subject is exposed. On the other hand, in the measure that the Saying is the expression of the significance which occurs in the proximity with the Other, the Saying is always testimonial. (shrink)

This paper attempts to demonstrate that in Emmanuel Levinas’ thinking, justice is the necessary opening – and dissolution- of the “I” which makes fecundity – procreation – possible, and that in that same measure makes possible that the Logos transforms into a “desire to say” and the world into a “among us”. At the same time it wants to demonstrate that this notion of justice is directly related to the ideas of expression and nudity. Due to which the “Other” imposes (...) itself in front of the “same” , as man, singular and vulnerable, and that in the same measure it is linked to the notion of the Face and its particular mode of manifestation. In this respect, we propose that justice. As long as necessary condition, can fund an ethically constituted world, where an “erotic order” mandates over logic orderings. (shrink)

The following essay aims to show how the image-record, the image produced by mechanical or technical means, seems to constitute a particular way of being-language, a kind of “animal limit” of being-language, that is, a “device ” which is intended to enroll and operate in the world in radically different ways than verbal and logical language. In this sense, we will deepen into the idea of “animal limit” reading some texts from Agamben and Levinas.

A characterization of the subdirectly irreducible separable dynamic algebras is presented. The notions develo- ped for this study were also suitable to describe the previously found class of simple separable dynamic algebras.

Este artículo indaga y reflexiona en torno a la «ontología del sentir» elaborada por Maurice Merleau-Ponty, especialmente sobre su noción de carne. Se procurará hacer evidente que la noción de carne es un intento radical de Merleau-Ponty para desarmar las nociones autónomas de sujeto elaboradas tanto por la modernidad filosófica como por la fenomenología, proponiendo en su lugar una noción «pasiva» de sujeto que está fundada en una primacía ontológica de la sensibilidad: en un Sensible en sí al que entiende (...) como «presencia originaria» y como «el trasfondo a partir del cual puede ser pensada toda donación de sentido». Igualmente, se pretende mostrar cómo esa «ontología del sentir» da lugar tanto a un «horizonte de invisibilidad» que subyace a toda representación como a una idea corporal, expresiva, gestual y creadora del lenguaje. (shrink)

Il gran "Theatro dell'Historia" -- La "priscorum hominum vita" -- La lingua di Saturno -- Geometria e fisica : la via "platonica" al sapere attivo.

ABSTRACTThe main objective of the New Philosophy was to ‘improve the lives of people and nations in part by improving medical practice’. To this end, Oliva Sabuco sought to improve humankind's know...