Results for 'Pinocchio syndrome'

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  1.  7
    The Pinocchio Syndrome and the Prosthetic Impulse.Victor Grech - 2014-08-11 - In Russell Blackford & Damien Broderick (eds.), Intelligence Unbound. Wiley. pp. 263–278.
    In this book the main emphasis is twofold: on autonomous machine intelligence, and on mind uploading. This chapter shows that, while science fiction (SF) has depicted the extreme embrace of the “prosthetic impulse,” most notoriously in Star Trek's“Borg,” this is used as a warning of the potential Faustian consequences of such tendencies. The Star Trek franchise has also highlighted the converse, the Pinocchio syndrome, a reverse prosthetic impulse, most notably in the android Commander Data. Data is a sentient (...)
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  2. AGICH, GEORGE, J. Joining the Team: Ethics Consultation at the Cleveland Clinic.Richard L. Allman, Mark Bernstein, Kerry Bowman Should, Kerry Bowman, Mark Bernstein Should & Munchausen Syndrome Proxy - 2003 - HEC Forum 15 (4):386-388.
     
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  3. Pinocchio beards the Barber.Peter Eldridge-Smith - 2012 - Analysis 72 (4):749-752.
    The Pinocchio paradox poses one dialetheia too many for semantic dialetheists (Eldridge-Smith 2011). However, Beall (2011) thinks that the Pinocchio scenario is merely an impossible story, like that of the village barber who shaves just those villagers who do not shave themselves. Meanwhile, Beall maintains that Liar paradoxes generate dialetheia. The Barber scenario is self-contradictory, yet the Pinocchio scenario requires a principle of truth for a contradiction. In this and other respects the Pinocchio paradox is a (...)
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  4. The pinocchio paradox.Peter Eldridge-Smith & Veronique Eldridge-Smith - 2010 - Analysis 70 (2):212-215.
    The Pinocchio paradox, devised by Veronique Eldridge-Smith in February 2001, is a counter-example to solutions to the Liar that restrict the use or definition of semantic predicates. Pinocchio’s nose grows if and only if what he is stating is false, and Pinocchio says ‘My nose is growing’. In this statement, ‘is growing’ has its normal meaning and is not a semantic predicate. If Pinocchio’s nose is growing it is because he is saying something false; otherwise, it (...)
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  5.  39
    Pinocchio against the Semantic Hierarchies.Peter Eldridge-Smith - 2018 - Philosophia 46 (4):817-830.
    The Liar paradox is an obstacle to a theory of truth, but a Liar sentence need not contain a semantic predicate. The Pinocchio paradox, devised by Veronique Eldridge-Smith, was the first published paradox to show this. Pinocchio’s nose grows if, and only if, what Pinocchio is saying is untrue. What happens if Pinocchio says that his nose is growing? Eldridge-Smith and Eldridge-Smith : 212-5, 2010) posed the Pinocchio paradox against the Tarskian-Kripkean solutions to the Liar (...)
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  6. Pinocchio against the dialetheists.Peter Eldridge-Smith - 2011 - Analysis 71 (2):306-308.
    Semantic dialetheists astutely dodge Explosion, the logical contagion of everything being true if a single contradiction is true. A dialetheia is contained in their semantics, and sustained by a paraconsistent logic. Graham Priest has shown that this is a solution to the Liar paradox. I use the Pinocchio paradox, devised by Veronique Eldridge-Smith, as a counter-example. The Pinocchio paradox turns on the truth of Pinocchio, whose nose grows if and only if what he is saying is not (...)
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  7.  10
    When Pinocchio becomes a real boy: Capability and felicity in AI and interactive depictions.John M. Carroll - 2023 - Behavioral and Brain Sciences 46:e25.
    Clark and Fischer analyze social robots as interactive depictions, presenting characters that people can interact with in social settings. Unlike other types of depictions, the props for social robot depictions depend on emerging interactive technologies. This raises questions about how such depictions depict: They conflate character and prop in ways that delight, confuse, mistreat, and may become ordinary human–technology interactions.
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  8. Pinocchio in Venice (London.Robert Coover - 1991 - Minerva 329.
     
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  9.  6
    Caro pinocchio: piccola genealogia del negativo.Remo Guidieri - 2001 - Roma: L'ancora del Mediterraneo.
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  10. Imposter Syndrome and Self-Deception.Stephen Gadsby - 2021 - Australasian Journal of Philosophy:1-12.
    Many intelligent, capable, and successful individuals believe that their success is due to luck and fear that they will someday be exposed as imposters. A puzzling feature of this phenomenon, commonly referred to as imposter syndrome, is that these same individuals treat evidence in ways that maintain their false beliefs and debilitating fears: they ignore and misattribute evidence of their own abilities, while readily accepting evidence in favour of their inadequacy. I propose a novel account of imposter syndrome (...)
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  11.  19
    Za koga Pinocchio sebe smatra?Sercan Çalcı - 2022 - Synthesis Philosophica 37 (1):3-22.
    In this article, I imagine a scene in Plato’s cave where Gilles Deleuze and Félix Guattari encounter Pinocchio, the most famous puppet. I want to examine the forms of resistance created by the expressions of the Body Without Organs during the process of Pinocchio’s formation and bring together the elements that undermine the pedagogical causality established between telling a lie and the elongation of the nose to show that a different reading of The Adventures of Pinocchio is (...)
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  12.  72
    physicalism, truth, and the Pinocchio paradox.Laureano Luna - 2016 - Mind and Matter 14 (1):77-86.
    We develop an argument sketched by Luna (2011) based on the Pinocchio paradox, which was proposed by Eldridge-Smith and Eldridge- Smith (2010). We show that, upon plausible assumptions, the claim that mental states supervene on bodily states leads to the conclusion that some proposition is both paradoxical and not paradoxical. In order to show how the presence of paradoxes can be harnessed for philosophical argumentation, we present as well a couple of related arguments.
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  13. Dialetheists against Pinocchio.Jc Beall - 2011 - Analysis 71 (4):689-691.
    This paper argues that, contrary to P. Eldridge-Smith, the so-called Pinocchio paradox affords no argument against ‘simply semantic dialetheism’.
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  14.  3
    Pinocchio nel paese dei paradossi: viaggio tra le contraddizioni della logica.Alessio Palmero Aprosio - 2012 - Milano (Italy): Sironi.
  15.  21
    Mr. pinocchio goes to Washington: Lying in politics.Robert Weissberg - 2004 - Social Philosophy and Policy 21 (1):167-201.
    A more provocative subject than “lying in politics” is difficult to imagine. Everybody, from the proverbial “Joe Sixpack” to ivory-tower philosophers, can wax eloquently on the subject, if only because easy-to-find, shocking examples abound. If moral outrage were judged an essential vitamin, then condemning dishonesty undoubtedly guarantees a daily megadose. Unfortunately, at least for those who crave self-indulgent outrage, the anti-lying case is less than 100 percent compelling. It is a quagmire of the first order, if only because those who (...)
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  16. Pinocchio and the puppet of Plato's Laws.Jeffrey Dirk Wilson - 2016 - In Geoffrey C. Kellow & Neven Leddy (eds.), On Civic Republicanism: Ancient Lessons for Global Politics. University of Toronto Press.
  17. Cotard syndrome, self-awareness, and I-concepts.Rocco J. Gennaro - 2020 - Philosophy and the Mind Sciences 1 (1):1-20.
    Various psychopathologies of self-awareness, such as somatoparaphrenia and thought insertion in schizophrenia, might seem to threaten the viability of the higher-order thought (HOT) theory of consciousness since it requires a HOT about one’s own mental state to accompany every conscious state. The HOT theory of consciousness says that what makes a mental state a conscious mental state is that there is a HOT to the effect that “I am in mental state M.” I have argued in previous work that a (...)
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  18.  1
    Le syndrome de Kierkegaard: Kierkegaard, Dieu et la femme.Jean-Luc Berlet - 2012 - Nice: Les Éditions Romaines.
    Le syndrome de Kierkegaard est un essai libre de Jean- Luc Berlet, consacré à l'un de ses penseurs de prédilection, le Danois Seren Kierkegaard (1813-1855). Ce syndrome dont il est question, tel que défini par l'auteur, pourrait être conçu comme la tension qui résulte de l'impossible choix entre l'amour de la femme et l'amour de Dieu. Kierkegaard renonça en effet à l'amour charnel de la femme au profit d'une vie ascétique consacrée à I écriture et à la réflexion (...)
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  19.  35
    The Pinocchio Problem.Jeffrey Carr - 2008 - Southwest Philosophy Review 24 (2):101-107.
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  20. Othello syndrome.David Enoch, Basant K. Puri & Hadrian Ball - 2020 - In David Enoch, Basant K. Puri & Hadrian Ball (eds.), Uncommon Psychiatric Syndromes. Routledge. pp. 51–73.
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  21. Arguing With Asperger Syndrome.Albert Atkin, J. E. Richardson & C. Blackmore - 2007 - In Albert Atkin, J. E. Richardson & C. Blackmore (eds.), Proceedings of the International Society for the Study of Argumentation (ISSA). pp. 1141-1146.
    The study examines the argumentative competencies of people with Asperger syndrome (AS) and compares this with those of normal – or what are called neurotypical (NT) – subjects. To investigate how people with AS recognise, evaluate and engage in argumentation, we have adapted and applied the empirical instrument developed by van Eemeren, Garssen and Meuffels to study the conventional validity of the pragma-dialectical freedom rule (van Eemeren, Gars- sen & Meuffels 2003a; 2003b; 2005a; 2005b; van Eemeren & Meuffels, 2002). (...)
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  22.  11
    Stroke Syndromes.Julien Bogousslavsky & Louis Caplan (eds.) - 1995 - Cambridge University Press.
    In this important addition to the stroke literature, highly experienced clinicians set out the patterns to be expected in patients with stroke, drawing on illustrative case histories where appropriate. The book is intended as a guide to patterns and syndromes for clinicians encountering an unfamiliar presentation in a stroke patient. It will enable them to differentiate between possible locations on the basis of symptoms and signs, recognise lesion patterns found in patients with infarcts and haemorrhages in various vascular territories, and (...)
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  23. The locked-in syndrome : what is it like to be conscious but paralyzed and voiceless?Serge Goldman - unknown
    1Neurology Department and Cyclotron Research Center, University of Lie`ge, Sart Tilman B30, 4000 Liege, Belgium 2Neurorehabilitation Medicine, Hoˆpital Caremeau, CHU Nıˆmes, 30029 Nıˆmes Cedex, France 3Department of Speech Therapy, Hospital Pitie´ Salpe´trie`re, Paris and French Association Locked in Syndrome (ALIS), 225 Bd Jean-Jaures, MBE 182, 92100 Boulogne-Billancourt, France 4Neurosciences et Syste`mes Sensoriels Unite´ Mixte de Recherche 5020, Universite´ Claude Bernard Lyon 1 – CNRS, 69007 Lyon, France 5Intensive Care Medicine, Hoˆpital Erasme, Universite´ Libre de Bruxelles, Route de Lennik 808, (...)
     
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  24.  10
    Williams syndrome : dissociation and mental structure.Mitch Parsell - unknown
    Williams syndrome is a genetic disorder that, because of its unique cognitive profile, has been marshalled as evidence for the modularity of both language and social skills. But emerging evidence suggests the claims of modularity based on WS have been premature. This paper offers an examination of the recent literature on WS. It argues the literature gives little support for mental modularity. Rather than being rigidly modular, the WS brain is an extremely flexible organ that that co-opts available neural (...)
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  25.  39
    Imposter Syndrome and Self-Deception.Stephen Gadsby - 2022 - Australasian Journal of Philosophy 100 (2):247-261.
    ABSTRACT Many intelligent, capable, and successful individuals believe that their success is due to luck, and fear that they will someday be exposed as imposters. A puzzling feature of this phenomenon, commonly referred to as imposter syndrome, is that these same individuals treat evidence in ways that maintain their false beliefs and debilitating fears: they ignore and misattribute evidence of their own abilities, while readily accepting evidence in favour of their inadequacy. I propose a novel account of imposter (...) as an instance of self-deception, whereby biased evidence treatment is driven by the motivational benefit of negative self-appraisal. This account illuminates a number of interconnected philosophical and scientific puzzles related to the explanation, definition, and value of imposter syndrome. (shrink)
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  26.  12
    Subjective Experiences of Tourette Syndrome: Beyond the Premonitory Urge.Daryl Efron, Ivan Mathieson & MClin Psych - 2024 - Philosophy, Psychiatry, and Psychology 31 (1):47-48.
    In lieu of an abstract, here is a brief excerpt of the content:Subjective Experiences of Tourette SyndromeBeyond the Premonitory UrgeThe authors report no conflicts of interest.There is an evolving recognition in healthcare that the patient's subjective experience needs to be privileged both in understanding clinical phenomena and also ensuring the salience of outcomes used to evaluate the impact of treatment interventions. This is reflected in the expansion of patient-reported outcome measures to capture a person's perception of their own health, and (...)
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  27.  16
    The Syndrome of Imbalance or Can We Listen Our Soul.Kenul Bunyadzade - 2008 - Proceedings of the Xxii World Congress of Philosophy 49:141-148.
    As a human being possesses dual creation, certain reasons and conditions can oppose his inner and outside worlds. Giving preference one side to other, and to turn another into slavery enhance the syndrome of imbalance which inherent him in birth. To make harmony between them and their complementarities perfect the human being. This also emphasizes the necessity of parallel development of rational and irrational thinking and their complementarities. A human being is perfect in birth and he is the only (...)
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  28. Severe Acute Respiratory Syndrome Coronavirus 2 Human Challenge Trials: Too Risky, Too Soon.Liza Dawson, Jake Earl & Jeffrey Livezey - 2020 - Journal of Infectious Diseases 222 (3):514-516.
    Eyal et al have recently argued that researchers should consider conducting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human challenge studies to hasten vaccine development. We have conducted (J. L.) and overseen (L. D.) human challenge studies and agree that they can be useful in developing anti-infective agents. We also agree that adults can autonomously choose to undergo risks with no prospect of direct benefit to themselves. However, we disagree that SARS-CoV-2 challenge studies are ethically appropriate at this time, (...)
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  29. Cultural syndromes: Socially learned but real.Marion Godman - 2016 - Filosofia Unisinos 17 (2).
    While some of mental disorders due to emotional distress occur cross-culturally, others seem to be much more bound to particular cultures. In this paper, I propose that many of these “cultural syndromes” are culturally sanctioned responses to overwhelming negative emotions. I show how tools from cultural evolution theory can be employed for understanding how the syndromes are relatively confined to and retained within particular cultures. Finally, I argue that such an account allows for some cultural syndromes to be or become (...)
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  30. Capgras Syndrome: A Novel Probe for Understanding the Neural Representation of the Identity and Familiarity of Persons.William Hirstein & V. S. Ramachandran - 1997 - Proceedings of the Royal Society of London B 264:437-444.
  31. Syndromes of the medulla oblongata.R. D. Currier - 1969 - In P. Vinken & G. Bruyn (eds.), Handbook of Clinical Neurology. North Holland. pp. 2--217.
     
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  32.  25
    Bloom syndrome helicase in meiosis: Pro-crossover functions of an anti-crossover protein.Talia Hatkevich & Jeff Sekelsky - 2017 - Bioessays 39 (9):1700073.
    The functions of the Bloom syndrome helicase and its orthologs are well characterized in mitotic DNA damage repair, but their roles within the context of meiotic recombination are less clear. In meiotic recombination, multiple repair pathways are used to repair meiotic DSBs, and current studies suggest that BLM may regulate the use of these pathways. Based on literature from Saccharomyces cerevisiae, Arabidopsis thaliana, Mus musculus, Drosophila melanogaster, and Caenorhabditis elegans, we present a unified model for a critical meiotic role (...)
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  33. Uncommon Psychiatric Syndromes.David Enoch, Basant K. Puri & Hadrian Ball (eds.) - 2020 - Routledge.
    This new edition expands on the previous editions as a valued source of information regarding uncommon psychiatric syndromes. Each chapter goes into detail on the essential facts of the mentioned syndromes, thus giving the reader a clear understanding of the material. The last edition was well received and is widely considered a classic text for those in the field, though now it is an outdated source. Since the publication of the fourth edition, there have been many developments in the field (...)
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  34.  10
    Adam and Eve and Pinocchio: on being and becoming human.Willard Gaylin - 1990 - New York N.Y., USA: Viking Press.
    Explores humanity's biological roots and astounding capacity for self-creation and self-alteration, examining freedom and choice, sexuality and love, conscience and justice, work and pleasure, and other issues.
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  35.  9
    Burnout Syndrome in Teachers of Health Sciences in Chachapoyas.Franz Tito Coronel-Zubiate, Olenka María Oblitas Pereyra, Yshoner Antonio Silva Díaz, Oscar Pizarro Salazar & Jeanile Zuta Rojas - 2023 - Human Review. International Humanities Review / Revista Internacional de Humanidades 21 (2):237-244.
    The research sought to determine the prevalence of Burnout Syndrome in health teachers at a university in north-eastern Peru. The universe was made up of 69 teachers, and 41 responded to the self-administered instrument called Maslach Burnout Inventory. The results show that 14.6% present this syndrome. The highest indicator was personal fulfillment, while depersonalization and emotional exhaustion were low. According to gender, in both it was similar. According to age group, it had a greater effect in ages between (...)
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  36. Syndromes of the diencephalon.B. Boshes - 1969 - In P. Vinken & G. Bruyn (eds.), Handbook of Clinical Neurology. North Holland. pp. 2--432.
     
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  37.  19
    Savant syndrome and prime numbers.Makoto Yamaguchi - 2009 - Polish Psychological Bulletin 40 (2):69-73.
    Savant syndrome and prime numbers Oliver Sacks reported that a pair of autistic twins had extraordinary number abilities and that they spontaneously generated huge prime numbers. Such abilities could contradict our understanding of human abilities. Sacks' report attracted widespread attention, and several researchers speculated theoretically. Unfortunately, most of the explanations in the literature are wrong. Here a correct explanation on prime number identification is provided. Fermat's little theorem is implemented in spreadsheet. Also, twenty years after the report, questionable aspects (...)
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  38.  14
    Williams Syndrome, Human Self-Domestication, and Language Evolution.Amy Niego & Antonio Benítez-Burraco - 2019 - Frontiers in Psychology 10.
    Language evolution resulted from changes in our biology, behavior, and culture. One source of these changes might be human self-domestication. Williams syndrome (WS) is a clinical condition with a clearly defined genetic basis and resulting in a distinctive behavioral and cognitive profile, including enhanced sociability. In this paper we show evidence that the WS phenotype can be satisfactorily construed as a hyper-domesticated human phenotype, plausibly resulting from the effect of the WS hemydeletion on selected candidates for domestication and neural (...)
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  39.  46
    Syndromic Surveillance and Patients as Victims and Vectors.Leslie P. Francis, Margaret P. Battin, Jay Jacobson & Charles Smith - 2009 - Journal of Bioethical Inquiry 6 (2):187-195.
    Syndromic surveillance uses new ways of gathering data to identify possible disease outbreaks. Because syndromic surveillance can be implemented to detect patterns before diseases are even identified, it poses novel problems for informed consent, patient privacy and confidentiality, and risks of stigmatization. This paper analyzes these ethical issues from the viewpoint of the patient as victim and vector. It concludes by pointing out that the new International Health Regulations fail to take full account of the ethical challenges raised by syndromic (...)
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  40.  89
    The Syndrome of Love.Ryan Stringer - 2020 - Ergo: An Open Access Journal of Philosophy 7:480-510.
    What is love? In this paper I argue that love is a psychological syndrome, or an enormously complex cluster of psychological attitudes and dispositions that’s accompanied by a corresponding set of symptoms that flow from it. More specifically, I argue that love is an affectionate loyalty that takes different shapes across cases and that manifests itself in some set of behavioral and emotional expressions, where this set of expressions also varies across cases. After laying down three theoretical constraints that (...)
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  41.  11
    Williams Syndrome and Music: A Systematic Integrative Review.Donovon Thakur, Marilee A. Martens, David S. Smith & Ed Roth - 2018 - Frontiers in Psychology 9.
    Background: Researchers and clinicians have often cited a strong relationship between individuals with Williams syndrome and music. This review systematically identified, analyzed, and synthesized research findings related to Williams syndrome and music. Methods: Thirty-one articles were identified that examined this relationship and were divided into seven areas. This process covered a diverse array of methodologies, with aims to: 1) report current findings; 2) assess methodological quality; and 3) discuss the potential implications and considerations for the clinical use of (...)
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  42. The Ganser syndrome.David F. Allen, Jacques Postel & German E. Berrios - 2000 - In G. Berrios & J. Hodges (eds.), Memory Disorders in Psychiatric Practice. Cambridge University Press. pp. 443.
    This chapter discusses the Ganser syndrome and gives a brief account on its clinical features. A significant number of clinicians in Europe continued accepting Ganser's basic postulates that the patients showed significant memory disorder and 'answers towards the question' within the framework of traumatic or reactive hysteria. In elderly patients, Ganser type symptoms may be indicative of the onset of dementia. Ganser syndrome raises the question of the interaction between concepts, ideology and clinical observation. The clinician must be (...)
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  43.  14
    The Wellness Syndrome.Carl Cederström & Andre Spicer - 2015 - Polity.
    _Not exercising as much as you should? Counting your calories in your sleep? Feeling ashamed for not being happier? You may be a victim of the wellness syndrome._ In this ground-breaking new book, Carl Cederström and André Spicer argue that the ever-present pressure to maximize our wellness has started to work against us, making us feel worse and provoking us to withdraw into ourselves. The Wellness Syndrome follows health freaks who go to extremes to find the perfect diet, (...)
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  44.  37
    Asperger syndrome and the supposed obligation not to bring disabled lives into the world.P. Walsh - 2010 - Journal of Medical Ethics 36 (9):521-524.
    Asperger syndrome (AS) is an autistic spectrum condition that shares the range of social impairments associated with classic autism widely regarded as disabling, while also often giving rise to high levels of ability in areas such as maths, science, engineering and music. The nature of this striking duality of disability and ability is examined, along with its implications for our thinking about disability and the relevance of levels and kinds of disability to reproductive choices. In particular, it may be (...)
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  45. The Anarchic Hand Syndrome and Utilization Behavior: A Window onto Agentive Self-Awareness.Elisabeth Pacherie - 2007 - Functional Neurology 22 (4):211 - 217.
    Two main approaches can be discerned in the literature on agentive self-awareness: a top-down approach, according to which agentive self-awareness is fundamentally holistic in nature and involves the operations of a central-systems narrator, and a bottom-up approach that sees agentive self-awareness as produced by lowlevel processes grounded in the very machinery responsible for motor production and control. Neither approach is entirely satisfactory if taken in isolation; however, the question of whether their combination would yield a full account of agentive self-awareness (...)
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  46.  15
    Rapunzel Shaves Pinocchio’s Beard.J. C. Beall - 2014 - In Elena Ficara (ed.), Contradictions: Logic, History, Actuality. De Gruyter. pp. 27-30.
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  47. Locked-in syndrome, bci, and a confusion about embodied, embedded, extended, and enacted cognition.Sven Walter - 2009 - Neuroethics 3 (1):61-72.
    In a recent contribution to this journal, Andrew Fenton and Sheri Alpert have argued that the so-called “extended mind hypothesis” allows us to understand why Brain Computer Interfaces (BCIs) have the potential to change the self of patients suffering from Locked-in syndrome (LIS) by extending their minds beyond their bodies. I deny that this can shed any light on the theoretical, or philosophical, underpinnings of BCIs as a tool for enabling communication with, or bodily action by, patients with LIS: (...)
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  48. Bálint’s syndrome, Object Seeing, and Spatial Perception.Craig French - 2018 - Mind and Language 33 (3):221-241.
    Ordinary cases of object seeing involve the visual perception of space and spatial location. But does seeing an object require such spatial perception? An empirical challenge to the idea that it does comes from reflection upon Bálint's syndrome, for some suppose that in Bálint's syndrome subjects can see objects without seeing space or spatial location. In this article, I question whether the empirical evidence available to us adequately supports this understanding of Bálint's syndrome, and explain how the (...)
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  49.  4
    Syndrom uprzedmiotowienia narodowego Polaków (dylematy upodmiotowienia polskiego społeczeństwa).Marcin Majewski - 2008 - Humanistyka I Przyrodoznawstwo 14:205-218.
    Syndrom uprzedmiotowienia narodowego Polaków jest systemem hamowania aktywności zbiorowej i jednostkowej. Wytwarzany jest poprzez redukcje instytucjonalnych podstaw samostanowienia obywateli, a pogłębiany z powodu niemożności akumulacji osobistej własności i gospodarowania dobrem wspólnym przez pojedyncze podmioty. Polega tez na blokowaniu personalnej dyspozycji do rozpoznania narzucanych zależności. W okresie transformacji politycznej w Polsce po 1989 roku takie strategie zostały skutecznie zastosowane.
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  50.  1
    Werner syndrome: Entering the helicase era.C. J. Epstein - 1996 - Bioessays 18 (12):1025-1027.
    Werner syndrome is a rare autosomal recessive disorder that mimics some of the characteristics of aging. The gene for this disorder has recently been identified as a helicase of the recQ subclass(1). Other phenotypically distinctive disorders caused by different helicase mutations include Bloom syndrome, Cockayne syndrome, xeroderma pigmentosum and trichothiodystrophy. Possible mechanisms by which helicases might produce the variable phenotypes are discussed. These include altered nucleotide excision repair and RNA polymerase II‐mediated transcription. The discovery of the helicase (...)
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