This paper investigates the Generalized Traveling Salesman Problem (GTSP), which is an extension of the well-known Traveling Salesman Problem (TSP), and it searches for an optimal tour in a clustered graph, such that every cluster is visited exactly once. In this paper, we describe a novel Memetic Algorithm (MA) for solving efficiently the GTSP. Our proposed MA has at its core a genetic algorithm (GA), completed by a Chromosome Enhancement Procedure (CEP), which is based on a TSP solver and the (...) Shortest Path (SP) algorithm and for improving the convergence characteristics of the GA, a Local Search (LS) operation is applied for the best chromosomes in each generation. We tested our algorithm on a set of well-known instances from the literature and the achieved results prove that our novel memetic algorithm is highly competitive against the existing solution approaches from the specialized literature. (shrink)

Review of Ioan-Aurel Pop, Biserică, societate şi cultură în Transilvania secolului al XVI-lea. Între acceptare şi excludere (Church, society and culture in 16 th Century Transylvania. Between acceptance and exclusion) , București: Editura Academiei, 2012.

This contribution explores Gilles Personne de Roberval’s 1644 Aristarchi Samii de mundi systemate, partibus, & motibus eiusdem, libellus. I focus on the complex circumstances of publication, the intellectual context of the polemics of Copernicanism within the scientific community, as well as the natural philosophy of the treatise. Roberval’s strategy of publication provides a very sophisticated example of authorship in early modern natural philosophy. The strategy lies at the conflux of certain specific motivations. I contextualize these motivations by accounting for the (...) delicate debates around the motion of the Earth in mid-seventeenth century Europe, the institutional communities of the Collège Royal and Mersenne’s circle, and the disciplinary bounds of Roberval’s professional authority. Weighing in all the elements, I argue that Roberval’s publication is an interesting intellectual game, playing with the notion of ancient authority and humanistic recovery. By this somewhat libertine attitude, Roberval takes a stance in a complicated debate around heliocentrism and the status of hypothetical cosmology. Roberval’s position is supported by his natural philosophical speculations, which I situate in the contemporary debates of the community. Roberval borrows from many philosophers, but he aims at achieving a highly systematic speculative cosmology. One of the functions of this system is to confirm Copernicanism, while maintaining a very pessimistic attitude on the prospects of precise astronomical knowledge and, among others, prognostication issues. (shrink)

In this paper we investigate a particular two-stage supply chain network design problem with fixed costs. In order to solve this complex optimization problem, we propose an efficient hybrid algorithm, which was obtained by incorporating a linear programming optimization problem within the framework of a genetic algorithm. In addition, we integrated within our proposed algorithm a powerful local search procedure able to perform a fine tuning of the global search. We evaluate our proposed solution approach on a set of large (...) size instances. The achieved computational results prove the efficiency of our hybrid genetic algorithm in providing high-quality solutions within reasonable running-times and its superiority against other existing methods from the literature. (shrink)

In this paper we aim to examine a novel view on distributive justice, i.e. limitarianism, which claims that it is morally impermissible to be rich. Our main goal is to assess the two arguments provided by Ingrid Robeyns in favour of limitarianism, namely the democratic argument and the argument from unmet urgent needs and the two distinct limitarian views which these arguments give rise to. We claim that strong limitarianism, which is supported by the democratic argument, should be rejected as (...) it fails to fully instantiate the value of political equality, while having some other unattractive implications as well. By contrast, we argue that weak limitarianism, which is supported by the argument from unmet urgent needs, should be endorsed, albeit in a qualified version which also takes responsibility constraints into consideration. (shrink)

The encounters of the Romanian philosopher C. Noica with his youger disciples - Gabriel Liicean, Andrei Pleșu, Sorin Vieru et alii - in the transylvanian Carpathian mountains, in the Păltiniș resort were perceived by Noica’s followers as a real philosophical school and an idealistic alternative to the compulsory marxist ideology. In spite of that, the orthodox thinker and literary critic N. Steinhardt took it as a way of avoiding the tough reality of communism and a negation of the Christian religion. (...) Therefore, he criticised that option and the pretention of the “Păltiniș School” to create a viable alternative to the officially imposed marxist vision. Steinhardt’s article received critical answers not only from the members of the so-called School, but also from another thinker and literary critic, Adrian Marino, who thought that both Noica and Steinhardt are wrong and the younger thinkers should act against Nicolae Ceaușescu’s agressive dictatorship by meas of civic and democratic activity. The study tries to emphasize the existence of more than one alternative to the communist ideology in Romania’s 1980s, generally considered as a frozen epoch for free philosophical and politically relevant discussions. (shrink)

Phosphatidylinositol‐3‐kinases (PI3Ks) are lipid kinases that produce 3‐phosphorylated derivatives of phosphatidylinositol upon activation by various cues. These 3‐phosphorylated lipids bind to various protein effectors to control many cellular functions. Lipid phosphatases such as phosphatase and tensin homolog (PTEN) terminate PI3K‐derived signals and are critical to ensure appropriate signaling outcomes. Many lines of evidence indicate that PI3Ks and PTEN, as well as some specific lipid effectors are highly compartmentalized, either in plasma membrane nanodomains or in endosomal compartments. We examine the evidence (...) for specific recruitment of PI3Ks, PTEN, and other related enzymes to membrane nanodomains and endocytic compartments. We then examine the hypothesis that scaffolding of the sources (PI3Ks), terminators (PTEN), and effectors of these lipid signals with a common plasma membrane nanodomain may achieve highly localized lipid signaling and ensure selective activation of specific effectors. This highlights the importance of spatial regulation of PI3K signaling in various physiological and disease contexts. (shrink)

This paper deals with Descartes’s and Roberval’s attempts to devise and describe the center of agitation of a composite pendulum. This episode has received some attention in the recent literature. It is usually depicted as the first step in the development of a general procedure for establishing the center of oscillation of a pendulum. My aim is to explore the different physical concepts and assumptions which informed the two mathematical accounts of the composite pendulum. I will argue that force, agitation, (...) heaviness, or resis­tance of air essentially meant different things for Descartes and Roberval. As a result, the physical phenomena covered by the two geometrical procedures were quite distinct, and both mathematicians envisaged different roles of these phenomena within their agenda of studying nature. (shrink)

On the Beginnings of the Greek Doctrine of the Transmigration of Souls. In this article, I state that attendant on the acceptance of the idea of an immortalsoul is a legitimate question concerning the soul's status before the individual's birth and after its death. Whether the Greeks were the originators of the doctrine of the transmigration of souls or this was an influence from another culture is still open to debate.

The task of my inquiry is to lay out the main lines of Eugen Fink’s reading of Kant, focusing on his interpretation of the Transcendental Dialectic. In the first part, I explain Fink’s claim that the Transcendental Dialectic represents the very heart of the Kantian project, in as much it is in this section of the first Critique that the question of totality (on Fink’s account, the driving impetus of this work) first comes to the forefront. Secondly, I undertake an (...) examination of Fink’s argument regarding the proper outcome of the “Antinomies of Pure Reason,” according to which the failure of the attempts to determine the world with “innerworldly models” is not a sufficient reason to contend that the world is merely a subjective idea. Finally, I discuss Fink’s thesis concerning the construction of the “Transcendental Ideal” according to which the transition from the omnitudo realitatis to the ens realissimum is not necessary (neither objectively, nor subjectively). In this regard, Fink’s project can be understood as an attempt to think the omnitudo realitatis for itself, prior to and independent from any realization in a being (be it a supreme one). (shrink)

The phenomenological tautology of life in Michel Henry’s works shows us that the radical concept of self-affection, in its own immanence, cannot be described in another way, either by metaphor or analogy for example, but only by that immediate relation like adequacy on itself: “life as life”. The reduplication of the fundamental concept in Henry’s last “theological” turn introduced a new Transcendence: the Self-Affection of the Absolute Life, the Christian God as Revelation. In this way, we can diversify the tautology (...) of life trying to read it using Saint Maximus the Confessor’s theology: “Life as Life” like the Absolute phenomenological Life of Trinity in Unity; “life as Life” for the creation of the human living by the Living God; “life as life” for the existence of the man, ek-sisting in a world affected by the original transgression; “Life as life” for the Incarnation of the Logos of God; “life as Life — 2” for the rebirth of the human living into Christ and His Mystical Body. (shrink)

Ioan Chirila, Cartea profetului Osea – Breviarum al gnoseologiei Vechiului Testament Editura Limes, 1999.

Sandu Frunza, Iubirea si Transcendenta. O introducere la problema spatiului median al experientei religioase in Iudaism si Crestinismul Rasaritean Editura Dacia, Cluj, 1999.

This paper presents the results of a within-subject experiment testing whether an increase in the monetary stakes by a factor of 50 – which had never been done before – influences individual behavior in a simple ultimatum bargaining game. Contrary to current wisdom, we found that lowest acceptable offers stated by the responder are proportionally lower in the high-stake condition than in the low-stake condition. This result may be interpreted in terms of the type of utility functions which characterize the (...) subjects. However, in line with prior results, we find that an important increase of the monetary stakes in the ultimatum game has no effect on the offers made by the proposer. Yet, the present research suggests that the reasons underlying these offers are quite different when the stakes are high. (shrink)

This study aims at showing how at the basis of Nikolai Berdyaev’s criticism of capitalism and Marxism lays the concept of Imago Dei. The Russian religious philosopher puts forward the Imago Dei as fundamental to the Christian understanding of human dignity. Berdyaev believes that in both capitalism and Marxism an objectification of the person takes place, and therefore a denial of basic human dignity. Berdyaev’s criticism of capitalism refers to its internal principles, partly building on Marx’s early criticism of capitalism. (...) Although he shared some of the same concerns with Marx and other Marxist theorists, ultimately his was a critique from a Christian perspective that was deeply humanistic, whereas Marxism in its Hegelian orientation had failed in achieving what Berdyaev understands as true humanism. Having confronted and engaged both systems of thought during his own life, Berdyaev’s insights are most interesting, and I argue in this paper that they are also relevant for our own reflections on these subjects today. (shrink)

The research on stem cell-based therapies has greatly expanded in recent years. Our text attempts to seek those religious and ethical challenges that stem cell therapy and research bring into debate. Our thesis is that bioethics can defend its principle without a religious background. We will develop our argumentation on three major points: firstly, a comparison between secular ethics and religious views will clarify why stem cell therapy and research are important from a scientific point of view, addressing the very (...) center of the human being; in our view, being based on secular society, bioethics can answer the challenges of stem cell therapy and research; secondly, following Hans Jonas' perspective on experimenting on humans, we seek to understand the philosophical guidance that sciences dealing with stem cell need; thirdly, we will map the ethical guidelines for clinical translational research that have been adopted by the International Society for Stem Cell Research. . (shrink)

This paper addresses the topic of bioethics in reproductive medicine from the perspective of the religious implications for the field. The assumption underlying the approach is that religion remains a factor that influences the field of bioethics even in a secularized postmodern society. The first part of the paper analyses the main bioethical issues which mark obstetrics and gynecology, uttering that the four basic principles of bioethics are available both in obstetrics and gynecology and must be applied in association with (...) the practitioner’s virtues. The second part of the paper focuses on the main directions that guide the debate on the presence of religion in the field of bioethics, with a special interest in their relevance for reproductive medicine. Despite the difficulties implied by the task of advocating for the place of religion at the secular table of deliberation in medical ethics, the relevance of religion for bioethics cannot be ignored. (shrink)

Dans ses Essais hérétiques sur la philosophie de l’histoire, Jan Patočka donne de la première guerre mondiale une interprétation située dans le sillage de l’interrogation historiale de Heidegger, dont il marque les limites et propose une radicalisation qui fait surgir la solidarité entre la technique et la guerre. Pour Patočka, qui s’appuie sur les récits de guerre de Jünger et de Teilhard de Chardin, la pensée historiale et les témoignages du front s’éclairent mutuellement : la saisie de la première guerre (...) comme « culmination du règne de la force » permet de rendre visibles un certain nombre d’expériences, dont celle du sacrifice. L’expérience du front contient le ferment d’un renversement, d’un « metanoein colossal et inouï », seul capable de miner les bases du système qui a conduit à la guerre et d’ouvrir ainsi une « paix véritable ». (shrink)

This paper aims to lay out the main tenets of Bernhard Waldenfels’s analyses of the experience of the alien and to confront the philosophical thesis underwriting them with a central insight stemming from Merleau-Ponty’s late philosophy. In the first section, I reconstruct the outlines of the experience of the alien, as described by Waldenfels, and show that, on his account, this experience can function as a powerful impetus enabling us to call into question some of the most deeply held commitments (...) of Western philosophical tradition: the sovereignty of the ego, the supremacy of order, the priority of the whole. In the second section, I show how a patient analysis of this experience compels us to undertake an inquiry concerning the “inter-world,” understood as the place of the encounter and the threshold of separation between the own and the alien. Finally, drawing on Merleau-Ponty’s alternative description of the “inter-world,” I maintain that Waldenfels’s account is insufficiently radical and show that the in-between realm cannot be assimilated to an interstice lodged between two insulated spheres. Rather, the “inter-world” should be conceived of as a shared dimension, subtending the partition between the spheres of ownness and alienness, as the one inclusive world. (shrink)

La question de l’histoire représente une thématique transversale dans l’œuvre de Patočka, le point de convergence d’un ensemble d’interrogations qui irriguent sa recherche philosophique. Dans la matrice théorique articulée autour de ce concept se trouvent imbriquées plusieurs orientations théoriques qui se prêtent difficilement à une lecture unitaire. En se penchant sur la question de l’histoire, Patočka cherche, tour à tour, à tracer la physionomie du présent et à porter à la lumière les ten...

The aim of this paper is to bring out the core commitments underlying Kojève’s ontological position. My main claim is that he designs an original ontological framework, which integrates (but also regionalizes) Hegel’s and Heidegger’s analysis, and which can be properly characterized as a “double dualism”. In order to assess this thesis, I discuss Kojève’s relationship to Heidegger and show that: a) on Kojève’s view, Heidegger’s phenomenology is marked by an attenuation of the scope of negativity which gives rise to (...) a tendentially monistic phenomenology; b) for Kojève, Heidegger’s main philosophical innovation is the idea of a dualist ontology. This thesis relies on Kojève’s hermeneutical conjecture that in the unpublished part of Being and Time Heidegger accomplishes a doubling (or a duplication) of ontology. (shrink)

The purpose of this paper is to lay out the similarities between the philosophical projects of Patočka and Merleau-Ponty, with respect to the question of the “limits of phenomenology”. We suggest that both these authors propose two complementary strategies in their attempt of overcoming the Husserlian phenomenology. The first one consists in extending the field of phenomenology so as for it to be able to encompass phenomena either insufficiently explored or misinterpreted by the conceptuality that Husserl put forth; the second (...) strategy, more ambitious, aims to overpass the very standpoint of phenomenology in favour of an ontological approach. We try to show that what profoundly motivates these attempts is a radical – and hence, ontological – reinterpretation of the Lebenswelt. (shrink)