Integrin‐mediated cell adhesion and subsequent cell spreading are essential for the growth and survival of many cell types. While integrin engagement is known to activate various signalling pathways, the role that cell spreading plays in the control of growth and survival is not clear. Using a novel technique, however, Chen et al.(1) demonstrate that the effect of cell spreading on growth and survival is not a consequence of increased area of contact with the extracellular matrix, supporting the hypothesis that regulation (...) through changes in cell tension and architecture play a key role. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Mimesis, Violence, and Socially Engaged Buddhism: Overture to a Dialogue Leo D. Lefebure University ofSaint Mary ofthe Lake René Girard's analysis ofdesire, mimetic rivalry, and the surrogate victim mechanism seeks to transform human consciousness in order to overcome seemingly intractable patterns ofrivalry and violence. In this project the Buddhist tradition, with its long commitment to nonviolence, its age-old suspicion of ordinary views of the self, and its ancient experience (...) of meditation as a transformative practice, exerts a claim to attention. The Buddhist tradition shares many of Girard's concerns: It denies the reality ofan autonomous, independent selfand calls attention to the interdependence ofall realities. It challenges its followers to become conscious ofthe sources oftheir own feelings and thoughts, to accept responsibility for them, and to be liberated from violence. Like Girard, Buddhism rejects the notion that there can be "good violence" as well as bad. For Buddhists, awakening from the illusions of the autonomous selfand freedom from violence are inseparable. The term, "Socially Engaged Buddhism," refers to a variety ofBuddhist move-ments since the 1950s which seek to apply ancient Buddhist principles to contemporary social, economic, and political problems. Powerful prejudices, however, threaten this conversation before it begins. Since the writings of Arthur Schopenhauer and Max Weber, Westerners have often seen Buddhism as a pessimistic religion, a worldnegating tradition that encourages the individual to withdraw from the world and seek a solitary salvation. The belief in karma has often been 122Leo D. Lefebure interpreted as fatalistic and inimical to social transformation. Buddhism, especially in the Mahayana traditions, has often accommodated to the dominant powers in society without exerting any effective social or political critique. Like every other major religious tradition, Buddhism has had an ambiguous history; and Westerners have often assumed prematurely that Buddhism has no history of social and political engagement whatsoever. Girard himself, in conversation with Jean-Claude Dussault in 1981, viewed Buddhism as a withdrawal from action in the world. Girard commented: Alors il me semble que la non-violence des religions orientales est la recherche d'une position hors de la violence, nirvana, etc., au prix de toute action. Mais cette recherche abandonne le monde en quelque sorte à lui-même. Alors il me semble que s'il fallait résumer d'un mot, ce serait un mot comme dégagement absolu par rapport à l'existence. ("Séminaire de recherche" 81) [It seems to me that the nonviolence of Eastern religions is the search for a position outside of violence, nirvana, etc., at the price ofall action. But this search abandons the world in a way to itself. Now it seems to me that if it were necessary to sum it up in a formula, it would be a phrase such as absolute détachement in regard to existence.] Later in the conversation, Girard expressed his own negative reaction: "Si vous voulez, je me sens profondément gréco-biblico-occidental face à ce renoncement nirvanesque total." (83) [If you please, I feel myself profoundly greco-biblical-occidental in contrast to this complete nirvanesque renunciation.] According to Girard's interpretation, Buddhism offers no constructive solution to the social problems ofrivalry and violence, but only an individual escape through withdrawal. Closely related to Girard's negative view ofBuddhism is his interpretation ofall non-biblical religions as channeling violence but as powerless to break the cycle ofviolence. He claims that only biblical revelation offers a basis for overcoming the violence of the surrogate victim mechanism: "To recognize Christ as God is to recognize him as the only being capable of rising above the violence that had, up to that point, absolutely transcended mankind. Violence is the controlling agent in every form ofmythic or cultural structure, and Christ is the only agent who is capable of escaping from these structures and freeing us from their dominance" (1987, Mimesis, Violence, and Socially Engaged Buddhism 123 219). Girard asserts that there is no common ground between the violenceridden mythologies which dominate all other religions and the revelation of God in Christianity (1986, 166). Girard is almost Barthian in his exclusivistic claims for Christian revelation, viewing all other religions as products of human mimetic striving and only Christianity as the true... (shrink)

We examine the influence of social capital in the municipal bond market. Defined as the norms and networks that encourage cooperation, social capital is a social construct which captures a region’s level of altruism, trustworthiness, and propensity to honor obligations. We expect that municipalities with high social capital are more trustworthy and likely to honor their debt obligations, which will result in lower bond yields. Our findings confirm that the bonds issued by municipalities located in high social capital counties exhibit (...) lower yields compared to the municipalities located in low social capital counties. Our findings are also supported by bond prices in the secondary market, which shows that bonds from the municipalities located in high social capital regions have higher prices. Additional tests reveal that the influence of social capital is stronger for general obligation bonds, suggesting that social capital matters more for bonds where the willingness of municipalities to pay taxes is an important factor. Lastly, we document that the bonds of municipalities in high social capital areas are less likely to have insurance, suggesting that social capital may act as a substitute for bond insurance. (shrink)

Philosophers often claim that forgiveness is a paradoxical phenomenon. I here examine two of the most widespread ways of dealing with the paradoxical nature of forgiveness. One of these ways, emblematized by Aurel Kolnai, seeks to resolve the paradox by appealing to the idea of repentance. Somehow, if a wrongdoer repents, then forgiving her is no longer paradoxical. I argue that this influential position faces more problems than it solves. The other way to approach the paradox, exemplified here by the (...) work of Jacques Derrida, is just too obscure to be by itself helpful. Yet, I argue that what I take to be its spirit is on the right track. I recommend distinguishing between the definition and the justification of forgiveness, and also between forgiveness understood as a mental phenomenon and an overt, communicative act. These distinctions are not given their due in the specialized literature, and I expose the nefarious consequences of this neglect. By focusing on forgiveness as a mental phenomenon I seek to analyze the root of the talk of paradoxes which surrounds the discussion of forgiveness. Finally, I present an analysis of forgiveness as a pure mental phenomenon, and argue that this analysis is the most important step in understanding forgiveness in any other sense. While my analysis reveals interesting aspects of forgiveness, it reveals, too, that forgiveness is not quite as paradoxical after all. (shrink)

The present volume contains articles of well-known representatives of the Meaning-Text Theory (MTT) and other related linguistic theories. Founded by I. Mel'cuk and A. Zholkovsky in the sixties in Moscow, MTT soon became known in the West as a “prominent outsider” theory. The picture changed since then, though. MTT gained importance in several areas of linguistics and computational linguistics. It influenced the design of new grammar formalisms such as Dependency Tree Grammars. Also, specific parts of MTT have been directly overtaken (...) into other theories; consider, for example, the work on integrating Lexical Functions into Pustejovsky's Generative Lexicon. The present volume is a further convincing demonstration of MTT's liveliness and relevance to the field's “burning” issues. The focus of the volume is on semantics, semantic representation and relation of semantics to surface in MTT. Six out of eight articles (Polguère; Escalier & Fournier; Paducheva; St.-Germain; Beck; Bogulavsky) deal with problems related to these topics, while the last two articles of the volume (Sgall and Rambow; Joshi) throw a bridge between MTT, or, more precisely, between dependency-based theories of which MTT is one instantiation, and other linguistic theories. (shrink)

"-- M. J. Silverthorne,The Humanities Association Review Leo Strauss (1899-1973) was the Robert Maynard Hutchins Distinguished Service Professor Emeritus of ...

This article offers a combined reading of Karl Löwith’s and Leo Strauss’s critique of social theory from the point of view of the natural law tradition broadly understood. Within the context of a growing interest in revisiting social theory’s debt to natural law, the piece seeks to unfold the connections between the two traditions without searching to restore any kind of natural law. Rather, it looks at their relationships as one of Aufhebung — the suspension and carrying forward — of (...) natural law premises within modern social theory. The works of these two writers point against conventional wisdom within social theory: Löwith’s secularization thesis calls into question the view of the irreligious nature of modernity’s historical break as well as its faith in immanent progress; Strauss’s reconstruction of natural law (right) gives due credit to the non-religious origins of modernity but at the price of withdrawing even more autonomy from any modern claim to self-assertion. Although some compatibility is recognizable in their critiques, I shall also be arguing that their substantive results point to opposite directions. A critical distance must also be maintained from their interpretations in the spirit of reinvigorating the project of modern social theory. (shrink)

Offering an innovative approach to critical thinking, Good Reasoning Matters! identifies the essential structure of good arguments in a variety of contexts and also provides guidelines to help students construct their own effective arguments. In addition to examining the most common features of faulty reasoning--slanting, bias, propaganda, vagueness, ambiguity, and a common failure to consider opposing points of view--the book introduces a variety of argument schemes and rhetorical techniques. This edition adds material on visual arguments and more exercises.

The essays are based on a long and intimate familiarity with the works, but the essay on Aristotle is especially important as one of Strauss's few writings on ...

' Here is Tolstoy's religion; and non-violence is at its heart. Simon Parke, author of The Beautiful Life.

Philosophers have in the past had difficulty in determining how to define ethical terms. here they are defined as open-context terms with a loosely limited range of substitution instances, in conformity with actual language usage. ethical terms are in themselves meaningless. it is a misuse to say, "x is wrong in itself." ethical terms then reduce to empirical terms concerning wants, likes, knowledge of cause and effect and consequences, knowledge of how ethical terms themselves work. ethical commands reduce to if-then (...) statements. blame may possibly never make sense. (shrink)

During the last decade, one source of debate in argumentation theory has been the notion that there are different modes of arguing that need to be distinguished when analyzing and evaluating arguments. Visual argument is often cited as a paradigm example. This paper discusses the ways in which it and modes of arguing that invoke non-verbal sounds, smells, tactile sensations, music and other non-verbal entities may be defined and conceptualized. Though some attempts to construct a ‘multimodal’ theory of argument are (...) criticized, it advocates for an argumentation theory that makes room for visual arguing and for other non-verbal modes that have not been explored in depth. In the process, the paper provides a method for identifying the structure of multimodal arguments and argues that adding modes to our theoretical tool box is an important step toward a comprehensive account of argument. (shrink)

This collection of Leo Abse's last essays are writings that he was working on from 2006 up to and during his final illness.

Deduction has frequently been condemned as a useless intellectual instrument because of its tautological character. To thoroughgoing opponents of rationalism, the pretensions of deduction are on the same level with those of induction. Both presume to yield more knowledge from the fact that we have some knowledge; and this is an impossible paradox, which not even so powerful an opponent of the “Philosophy of Experience” as Bradley could resolve to his own satisfaction. I wish in this brief note to indicate (...) how this semblance of paradox may very easily be removed without having to deny, as has often been thought necessary, the tautologicality of deduction. (shrink)

This uniquely fascinating volume is not merely a learned treatise in historical semantics; it is itself a stupendous display of world harmony as a creed-a vivid demonstration that "all is all.".

Most infonnallogic texts and articles assume a verbal account of reasoning which defines "argument" as a set of sentences. The present paper broadens this definition in order to account for "visual arguments" which are communicated with nonverbal visual images. Standard approaches to verbal arguments are extended in a way that allows them to explain and evaluate visual argumentation.

Punishment is a phenomenon which occurs in many contexts. Discussions of punishment assume punishment is criminal punishment carried out by the State. This book contains an account of punishment which overcomes the difficulties of competing accounts and treats punishment comprehensibly to better understand how it differs from similar phenomena, discussing its justification fruitfully.

Politics, Philosophy & Economics, Volume 21, Issue 4, Page 347-371, November 2022. We sometimes have to choose between options that are seemingly incomparable insofar as they seem to be neither better than, worse than, nor equal to each other. This often happens when the available options are quite different from one another. For instance, consider a choice between prioritizing either criminal justice reform or healthcare reform as a public policy goal. Even after the relevant details of the goals and possible (...) reforms are filled in, it is plausible that neither goal is better than, worse than, nor equal to the other. Such seemingly incomparable options present a problem for rational choice since it is unclear how an agent might rationally choose between them. What we need are some principles to help govern rational choice when faced with seemingly incomparable options. I here present three such principles. While each principle is individually compelling, I show that they are jointly incompatible. I then argue that the correct response to this inconsistent triad is to reject the principle that rationally censures performing a sequence of choices one knows will result in a suboptimal outcome. The upshot is that when seeming incomparability is involved, an agent can money pump themselves without being less rational for it. (shrink)

The age-old debate about what constitutes just punishment has become deadlocked. Retributivists continue to privilege desert over all else, and consequentialists continue to privilege punishment's expected positive consequences, such as deterrence or rehabilitation, over all else. In this important intervention into the debate, Leo Zaibert argues that despite some obvious differences, these traditional positions are structurally very similar, and that the deadlock between them stems from the fact they both oversimplify the problem of punishment. Proponents of these positions pay insufficient (...) attention to the conflicts of values that punishment, even when justified, generates. Mobilizing recent developments in moral philosophy, Zaibert offers a properly pluralistic justification of punishment that is necessarily more complex than its traditional counterparts. An understanding of this complexity should promote a more cautious approach to inflicting punishment on individual wrongdoers and to developing punitive policies and institutions. (shrink)

Informal logic is an attempt to develop a logic that can assess and analyze the arguments that occur in natural language discourse. Discussions in the field may address instances of scientific, legal, and other technical forms of reasoning, but the overriding aim has been a comprehensive account of argument that can explain and evaluate the arguments found in discussion, debate and disagreement as they manifest themselves in daily life — in social and political commentary; in news reports and editorials in (...) the mass media ; in advertising and corporate and governmental communications; and in personal exchange. (shrink)

For much of the first fifty years of its existence, analytic philosophy shunned discussions of normativity and ethics. Ethical statements were considered as pseudo-propositions, or as expressions of pro- or con-attitudes of minor theoretical significance. Nowadays, in contrast, prominent analytic philosophers pay close attention to normative problems. Here we focus our attention on the work of Searle, at the same time drawing out an important connection between Searle’s work and that of two other seminal figures in this development: H.L.A. Hart (...) and John Rawls. We show that all three thinkers tend to assume that there is but one type of normativity within the realm of social institutions – roughly, the sort of normativity that is involved in following the results of chess – and that they thereby neglect features that are of crucial significance for an adequate understanding of social reality. (shrink)

In this paper, I explore what gives collective testimony its epistemic credentials, through a critical discussion of three competing accounts of the epistemology of collective testimony. According to the first view, collective testimony inherits its epistemic credentials from the beliefs the testimony expresses— where this can be seen either as the beliefs of all or some of the group’s members, or as the beliefs of group itself. The second view denies any necessary connection to belief, claiming instead that the epistemic (...) credentials of collective testimony derive from the reliability or truth-conduciveness of the statement that expresses the testimony. Finally, the third view claims that the epistemic credentials of collective testimony derive from the fact that it involves undertaking a collective commitment to trustworthiness, which makes the group susceptible to rebuke and blame if its testimony is not trustworthy. I argue that this last account holds the most promise for preserving what is distinctive about testimonial knowledge while still underwriting a robust epistemology of collective testimony. (shrink)

In the paper ‘COVID-19 vaccine boosters for young adults: a risk–benefit assessment and ethical analysis of mandate policies at universities,’ Bardoshet alargued that college mandates of the COVID-19 booster vaccine are unethical. The authors came to this conclusion by performing three different sets of comparisons of benefits versus risks using referenced data and argued that the harm outweighs the risk in all three cases. In this response article, we argue that the authors frame their arguments by comparing values that are (...) not scientifically or reasonably comparable and that the authors used values that represent grossly different risk profiles and grouped them into a set of figures to create an illusion of fair comparisons. We argue that absent the falsely skewed portrayals of a higher level of risk over benefit in their misrepresented figures, the five ethical arguments they presented completely fall apart. (shrink)

Over the past few decades, Indigenous communities have successfully campaigned for greater inclusion in decision-making processes that directly affect their lands and livelihoods. As a result, two important participatory rights for Indigenous peoples have now been widely recognized: the right to consultation and the right to free, prior and informed consent (FPIC). Although these participatory rights are meant to empower the speech of these communities—to give them a proper say in the decisions that most affect them—we argue that the way (...) these rights have been implemented and interpreted sometimes has the opposite effect, of denying them a say or ‘silencing’ them. In support of this conclusion we draw on feminist speech act theory to identify practices of locutionary, illocutionary, and perlocutionary group silencing that arise in the context of consultation with Indigenous communities. (shrink)

According to a dominant understanding, the illocutionary domain is a bifurcated one, an amalgam containing both communicative speech acts (such as requesting and promising) and ceremonial speech acts (such as saying ‘I do’ in a marriage ceremony and naming a ship). Bifurcating the domain in this manner is commonly taken to be a primary lesson of Austin’s “How To Do Things With Words’, alongside that of according communicative speech acts a far greater prominence in terms of our core understanding of (...) illocution. In contrast, we draw on the resources provided by Austin’s work to provide a more unified conception of the illocutionary domain, one in which differences between communicative and ceremonial acts are themselves understood to emerge from a broader understanding of the illocutionary character of speech. (shrink)

With a view to the theme of church renewal, this article explores the role of a well-known and popular phrase in the Reformed tradition within Protestantism, that is, ecclesia reformata semper reformanda [‘the reformed church should always be reformed’]. Is this a helpful slogan when considering the possibilities and the limitations of church renewal? Firstly, the historical background of this phrase is described: it is rooted in the Dutch Reformed tradition, and only in the 20th century it was widely recognised (...) in Reformed circles. Against this background the hermeneutical problem, linked with the principle of sola Scriptura, is presented, and put into an ecumenical ecclesiological perspective: the church is grounded in the gospel. Finally, the article focuses on church polity as an important field of renewal, taking into account Karl Barth’s interpretation of this phrase. From this perspective, a balanced and ecumenical approach of church renewal is possible. (shrink)

Language has a rich typology of inferential types. It was recently shown that subjects are able to divide the informational content of new visual stimuli among the various slots of the inferential typology: when gestures or visual animations are used in lieu of specific words in a sentence, they can trigger the very same inferential types as language alone (Tieu et al., 2019 ). How general are the relevant triggering algorithms? We show that they extend to the auditory modality and (...) to music cognition. We tested whether pro-speech musical gestures, i.e. musical excerpts that replace words in sentences, can give rise to the same inferences. We show that it is possible to replicate the same typology of inferences using pro-speech music. Minimal and complex musical excerpts can behave just like language, gestures, and visual animations with respect to the logical behavior of their content when embedded in sentences. Specifically, we found that pro-speech music can generate scalar implicatures, presuppositions, supplements, and homogeneity inferences. (shrink)