How epithelial tissues are able to self-renew to maintain homeostasis and regenerate in response to injury remains a persistent question. The transcriptional effectors YAP and TAZ are increasingly being recognized as central mediators of epithelial stem cell biology, and a wealth of recent studies have been directed at understanding the control and activity of these factors. Recent work by Hu et al. has added to this knowledge, as they identify an Integrin-FAK-CDC42-PP1A signaling cascade that directs nuclear YAP/TAZ activity in stem (...) cell populations of the mouse incisor, and define convergence on mTORC1 signaling as an important mediator of the proliferation of these cells. Here, we review recent studies on YAP/TAZ function and regulation in epithelial tissue-specific stem cells, merging the Hu et al. study together with our current knowledge of YAP/TAZ. The Hippo pathway effectors YAP and TAZ broadly regulate adult stem cells, and have recently been implicated in dental epithelial stem cell proliferation and restricted differentiation via an Integrin-FAK-CDC42-PP1A cascade. Here, we discuss the extracellular cues which control YAP/TAZ activity and examine downstream pathways that direct stem cell fate. (shrink)

How epithelial tissues are able to self-renew to maintain homeostasis and regenerate in response to injury remains a persistent question. The transcriptional effectors YAP and TAZ are increasingly being recognized as central mediators of epithelial stem cell biology, and a wealth of recent studies have been directed at understanding the control and activity of these factors. Recent work by Hu et al. has added to this knowledge, as they identify an Integrin-FAK-CDC42-PP1A signaling cascade that directs nuclear YAP/TAZ activity in stem (...) cell populations of the mouse incisor, and define convergence on mTORC1 signaling as an important mediator of the proliferation of these cells. Here, we review recent studies on YAP/TAZ function and regulation in epithelial tissue-specific stem cells, merging the Hu et al. study together with our current knowledge of YAP/TAZ. The Hippo pathway effectors YAP and TAZ broadly regulate adult stem cells, and have recently been implicated in dental epithelial stem cell proliferation and restricted differentiation via an Integrin-FAK-CDC42-PP1A cascade. Here, we discuss the extracellular cues which control YAP/TAZ activity and examine downstream pathways that direct stem cell fate. (shrink)

This book examines cultural recognition and the struggle for identity in America's schools. In particular, the contributing authors focus on the recognition and misrecognition as antagonistic cultural forces that work to shape, and at times distort identity.

G protein‐coupled receptors (GPCRs) are the largest family of transmembrane receptors and primarily signal through two main effector proteins: G proteins and β‐arrestins. Many agonists of GPCRs promote “biased” responses, in which different cellular signaling pathways are activated with varying efficacies. The mechanisms underlying biased signaling have not been fully elucidated, with many potential “hidden variables” that regulate this behavior. One contributor is “location bias,” which refers to the generation of unique signaling cascades from a given GPCR depending upon the (...) cellular location at which the receptor is signaling. Here, we review evidence that GPCRs are expressed at and traffic to various subcellular locations and discuss how location bias can impact the pharmacologic properties and characterization of GPCR agonists. We also evaluate how differences in subcellular environments can modulate GPCR signaling, highlight the physiological significance of subcellular GPCR signaling, and discuss the therapeutic potential of exploiting GPCR location bias. (shrink)

According to an increasingly popular epistemological view, people need outright beliefs in addition to credences to simplify their reasoning. Outright beliefs simplify reasoning by allowing thinkers to ignore small error probabilities. What is outright believed can change between contexts. It has been claimed that thinkers manage shifts in their outright beliefs and credences across contexts by an updating procedure resembling conditionalization, which I call pseudo-conditionalization (PC). But conditionalization is notoriously complicated. The claim that thinkers manage their beliefs via PC is (...) thus in tension with the view that the function of beliefs is to simplify our reasoning. I propose to resolve this puzzle by rejecting the view that thinkers employ PC. Based on this solution, I furthermore argue for a descriptive and a normative claim. The descriptive claim is that the available strategies for managing beliefs and credences across contexts that are compatible with the simplifying function of outright beliefs can generate synchronic and diachronic incoherence in a thinker’s attitudes. Moreover, I argue that the view of outright belief as a simplifying heuristic is incompatible with the view that there are ideal norms of coherence or consistency governing outright beliefs that are too complicated for human thinkers to comply with. (shrink)

This interpretive introduction provides unique insight into Plato's Republic. Stressing Plato's desire to stimulate philosophical thinking in his readers, Julia Annas here demonstrates the coherence of his main moral argument on the nature of justice, and expounds related concepts of education, human motivation, knowledge and understanding. In a clear systematic fashion, this book shows that modern moral philosophy still has much to learn from Plato's attempt to move the focus from questions of what acts the just person ought to (...) perform to the more profound questions of what sort of person the just person ought to be. (shrink)

Humean Laws for Human Agents presents cutting-edge research by leading experts on the Humean account of laws, chance, possibility, and necessity. A central question in metaphysics and philosophy of science is: What are laws of nature? Humeans hold that laws are not sui generis metaphysical entities but merely particularly effective summaries of what actually happens. The most discussed recent work on Humeanism emphasizes the laws' usefulness for limited agents and uses pragmatic considerations to address fundamental and long-standing problems. The current (...) volume develops and critically examines pragmatic Humean accounts, with innovative new work on the epistemology of laws and chance, the problem of induction, counterfactuals, special science laws, and a Humean account of essence. Taken together, the papers provide a roadmap for developing pragmatic Humeanism and connate views, setting the agenda for future research. (shrink)

In this paper I am concerned with the question of whether degrees of belief can figure in reasoning processes that are executed by humans. It is generally accepted that outright beliefs and intentions can be part of reasoning processes, but the role of degrees of belief remains unclear. The literature on subjective Bayesianism, which seems to be the natural place to look for discussions of the role of degrees of belief in reasoning, does not address the question of whether degrees (...) of belief play a role in real agents’ reasoning processes. On the other hand, the philosophical literature on reasoning, which relies much less heavily on idealizing assumptions about reasoners than Bayesianism, is almost exclusively concerned with outright belief. One possible explanation for why no philosopher has yet developed an account of reasoning with degrees of belief is that reasoning with degrees of belief is not possible for humans. In this paper, I will consider three arguments for this claim. I will show why these arguments are flawed, and conclude that, at least as far as these arguments are concerned, it seems like there is no good reason why the topic of reasoning with degrees of belief has received so little attention. (shrink)

Epistemic permissivism is the view that it is possible for two people to rationally hold incompatible attitudes toward some proposition on the basis of one body of evidence. In this paper, I defend a particular version of permissivism – unacknowledged permissivism (UP) – which says that permissivism is true, but that no one can ever rationally believe that she is in a permissive case. I show that counter to what virtually all authors who have discussed UP claim, UP is an (...) attractive view: it is compatible with the intuitive motivations for permissivism and avoids a significant challenge to permissivism: the arbitrariness objection. (shrink)

Many philosophers hold that the probability axioms constitute norms of rationality governing degrees of belief. This view, known as subjective Bayesianism, has been widely criticized for being too idealized. It is claimed that the norms on degrees of belief postulated by subjective Bayesianism cannot be followed by human agents, and hence have no normative force for beings like us. This problem is especially pressing since the standard framework of subjective Bayesianism only allows us to distinguish between two kinds of credence (...) functions—coherent ones that obey the probability axioms perfectly, and incoherent ones that don’t. An attractive response to this problem is to extend the framework of subjective Bayesianism in such a way that we can measure differences between incoherent credence functions. This lets us explain how the Bayesian ideals can be approximated by humans. I argue that we should look for a measure that captures what I call the ‘overall degree of incoherence’ of a credence function. I then examine various incoherence measures that have been proposed in the literature, and evaluate whether they are suitable for measuring overall incoherence. The competitors are a qualitative measure that relies on finding coherent subsets of incoherent credence functions, a class of quantitative measures that measure incoherence in terms of normalized Dutch book loss, and a class of distance measures that determine the distance to the closest coherent credence function. I argue that one particular Dutch book measure and a corresponding distance measure are particularly well suited for capturing the overall degree of incoherence of a credence function. (shrink)

Epistemic utility theory seeks to establish epistemic norms by combining principles from decision theory and social choice theory with ways of determining the epistemic utility of agents’ attitudes. Recently, Moss, 1053–69, 2011) has applied this strategy to the problem of finding epistemic compromises between disagreeing agents. She shows that the norm “form compromises by maximizing average expected epistemic utility”, when applied to agents who share the same proper epistemic utility function, yields the result that agents must form compromises by splitting (...) the difference between their credence functions. However, this “split the difference” norm is in conflict with conditionalization, since applications of the two norms don’t commute. A common response in the literature seems to be to abandon the procedure of splitting the difference in favor of compromise strategies that avoid non-commutativity. This would also entail abandoning Moss’ norm. I explore whether a different response is feasible. If agents can use epistemic utility-based considerations to agree on an order in which they will apply the two norms, they might be able to avoid diachronic incoherence. I show that this response can’t save Moss’ norm, because the agreements concerning the order of compromising and updating it generates are not stable over time, and hence cannot avoid diachronic incoherence. I also show that a variant of Moss’ norm, which requires that the weights given to each agent’s epistemic utility change in a way that ensures commutativity, cannot be justified on epistemological grounds. (shrink)

This paper proposes a novel answer to the question of what attitude agents should adopt when they receive misleading higher-order evidence that avoids the drawbacks of existing views. The answer builds on the independently motivated observation that there is a difference between attitudes that agents form as conclusions of their reasoning, called terminal attitudes, and attitudes that are formed in a transitional manner in the process of reasoning, called transitional attitudes. Terminal and transitional attitudes differ both in their descriptive and (...) in their normative properties. When an agent receives higher-order evidence that they might have reasoned incorrectly to a belief or credence towards p, then their attitude towards p is no longer justified as a terminal attitude towards p, but it can still be justified as a transitional attitude. This view, which I call the unmooring view, allows us to capture the rational impact of misleading higher-order evidence in a way that integrates smoothly with a natural picture of epistemic justification and the dynamics of deliberation. (shrink)

In recent years, the "science of science" has combined computational methods with novel data sources in order to understand the dynamics of research communities. As the name suggests, science of science is primarily focused on science and technology, with less attention to the humanities. However, many of the questions investigated by science of science are also relevant to academic philosophy: To what extent can the discipline be divided into subfields with different methods and topics? How are prestige and credit distributed (...) across the discipline? And how do these factors interact with other factors, such as gender, to shape job market outcomes? In this paper, we provide some empirically-informed answers to these questions by applying computational methods to job market data for Anglophone academic philosophy. We find, first, evidence that is consistent with the analytic-continental divide, but is also consistent with other, more complex ways of organizing academic philosophy into distinct intellectual traditions; second, a clear prestige hierarchy, dividing PhD programs into two distinct prestige categories; and third, evidence that gender, prestige, and country have notable effects on academic job market outcomes for recent philosophy PhDs. (shrink)

Males are selectively afflicted with the neurodevelopmental and psychiatric disorders of childhood, a broad and virtually ubiquitous phenomenon that has not received proper attention in the biological study of sex differences. The previous literature has alluded to psychosocial differences, genetic factors and elements pertaining to male “complexity” and relative immaturity, but these are not deemed an adequate explanation for selective male affliction. The structure of sex differences in neurodevelopmental disorders is hypothesized to contain these elements: Males are more frequently afflicted, (...) females more severely; disorders arising in females are largely mediated by the genotype; in males, by a genotype by environment interaction; complications of pregnancy and delivery occur more frequently with male births; such complications are decisive and influence subsequent development. We hypothesize that there is something about the male fetus that evokes an inhospitable uterine environment. This “evocative principle” is hypothesized to relate to the relative antigenicity of the male fetus, which may induce a state of maternal immunoreactivity, leading either directly or indirectly to fetal damage. The immunoreactive theory thus constructed is borrowed from studies of sex ratios and is the only explanation consistent with negative parity effects in the occurrence of pregnancy complications and certain neurodevelopmental disorders. Although the theory is necessarily speculative, it is heuristic and hypotheses derived from it are proposed; some are confirmed in the existing literature and by the authors' research. (shrink)

Sorensen offers the following definition of a ‘knowledge-lie’: ‘An assertion that p is a knowledge-lie exactly if intended to prevent the addressee from knowing that p is untrue but is not intended to deceive the addressee into believing p.’ According to Sorensen, knowledge-lies are not meant to deceive their addressee, and this fact is supposed to make them less bad than ordinary lies. I will argue that standard cases of knowledge-lies, including almost all the cases Sorensen considers, do in fact (...) involve deception, contrary to what Sorensen claims. And while there are cases of non-deceptive knowledge-lies, such cases are deviant, either because it is only incidental that the knowledge-preventing assertion is a lie, or because it is only incidental that the lie doesn't deceive. Here's an example of a knowledge-lie: Dr Head is considering firing Dr Appendix because of his weak research. But he doesn't want to fire Appendix unless he knows that Appendix's research isn't good, and so he consults Dr Heart. Head knows that if Appendix's research is good, then Heart will tell the truth and say so, whereas if Appendix's work isn't good, then Heart may or may not …. (shrink)

Active reasoning is the kind of reasoning that we do deliberately and consciously. In characterizing the nature of active reasoning and the norms it should obey, the question arises which attitudes we can reason with. Many authors take outright beliefs to be the attitudes we reason with. Others assume that we can reason with both outright beliefs and degrees of belief. Some think that we reason only with degrees of belief. In this paper I approach the question of what kinds (...) of beliefs can participate in reasoning by using the following method: I take the default position to be maximally permissive – that both graded and outright beliefs can participate in reasoning. I then identify some features of active reasoning that appear at first glance to favor a more restrictive position about which types of belief we can reason with. I argue that the arguments based on these features ultimately fail. (shrink)

Ideal agents are role models whose perfection in some normative domain we try to approximate. But which form should this striving take? It is well known that following ideal rules of practical reasoning can have disastrous results for non-ideal agents. Yet, this issue has not been explored with respect to rules of theoretical reasoning. I show how we can extend Bayesian models of ideally rational agents in order to pose and answer the question of whether non-ideal agents should form new (...) degrees of belief in the same way as their ideal counterparts. I demonstrate that the epistemic and the practical case are parallel: following ideal rules does not always lead to optimal outcomes for non-ideal agents. (shrink)

ABSTRACT A robust literature indicates that when people feel that they are expressing and aware of their true selves, they show enhanced psychological health and well-being. This feeling, commonly referred to as authenticity, is therefore a consequential experience. In this paper, we review a program of research focused on the relevance of authenticity for civic engagement. We describe how a virtuous orientation to civic engagement might make civic actions feel more authentic and how the experience of authenticity might help sustain (...) civic behavior. We then discuss the role that education might play in fostering a deeper connection between civic engagement and the subjective experience of authenticity. (shrink)

In the literature on philosophical progress it is often assumed that agreement is a necessary condition for progress. This assumption is sensible only if agreement is a reliable sign of the truth, since agreement on false answers to philosophical questions would not constitute progress. This paper asks whether agreement among philosophers is (or would be) likely to be a reliable sign of truth. Insights from social choice theory are used to identify the conditions under which agreement among philosophers would be (...) a reliable indicator of the truth, and it is argued that we lack good reason to think that philosophical inquiry meets these conditions. The upshot is that philosophical agreement is epistemically uninformative: agreement on the answer to a philosophical question does not supply even a prima facie reason to think that the agreed-upon view is true. However, the epistemic uninformativeness of philosophical agreement is not an indictment of philosophy's progress, because philosophy is valuable independent of its ability to generate agreement on the correct answers to philosophical questions. (shrink)

In November 1996, Catherine Clément and Julia Kristeva began a correspondence exploring the subject of the sacred. In this collection of those letters Catherine Clément approaches the topic from an anthropologist's point of view while Julia Kristeva responds from a psychoanalytic perspective. Their correspondence leads them to a controversial and fundamental question: is there anything sacred that can at the same time be considered strictly feminine? The two voices of the book work in tandem, fleshing out ideas and (...) blending together into a melody of experience. The result is a dialogue that delves into the mysteries of belief -- the relationship between faith and sexuality, the body and the senses -- which, Clément and Kristeva argue, women feel with special intensity. Although their discourse is not necessarily about theology, the authors consider the role of women and femininity in the religions of the world, from Christianity and Judaism to Confucianism and African animism. They are the first to admit that what they have undertaken is "as impossible to accomplish as it is fascinating." Nevertheless, their wide-ranging and exhilarating dialogue succeeds in raising questions that are perhaps more important to ask than to answer. (shrink)

The concept of imagination is notoriously ambiguous. Thus one must be cautious not to use ‘imagination’ as a placeholder for diverse phenomena and processes that perhaps have not much more in common than that they are difficult to assign to some other, better defined domain, such as perception, conceptual thought, or artistic production. However, this challenge also comes with great opportunities: the fecundity and openness of ‘imagination’ appeal to researchers from different disciplines with different approaches and questions, and it draws (...) together fields of enquiry that are initially considered far apart. Hence, arguably, the field of imagination is particularly poised for interdisciplinary enquiry. In the section on Imagination in Interdisciplinary Research, I will talk about some of the issues that have already entered that field of interdisciplinary inquiry. (shrink)

The aim of this paper is to examine whether it would be advantageous to introduce knowledge norms instead of the currently assumed rational credence norms into the debate about decision making under normative uncertainty. There is reason to think that this could help us better accommodate cases in which agents are rationally highly confident in false moral views. I show how Moss’ view of probabilistic knowledge can be fruitfully employed to develop a decision theory that delivers plausible verdicts in these (...) cases. I also argue that, for this new view to be better than existing alternatives, it must adopt a particular solution to the new evil demon problem, which asks whether agents and their BIV-counterparts are equally justified. In order to get an attractive decision theory for cases of moral uncertainty, we must reject the claim that agents and their BIV-counterparts are equally justified. Moreover, the resulting view must be supplemented with a moral epistemology that explains how it is possible to be rationally morally uncertain. This is especially challenging if we assume that moral truths are knowable a priori. (shrink)

This paper proposes a conceptual framework of multiversional narrative processing, or multiversionality. Multiversionality is the consideration of multiple possible event sequences for an incomplete narrative during reception, from reading a novel to listening to the story of a friend’s day. It occurs naturally and is experienced in a wide range of cases, such as suspense, surprise, counterfactuals, and detective stories. Receiving a narrative, we propose, is characterized by the spontaneous creation of competing interpretive models of the narrative that are then (...) used to create predictions and projections for the narrative’s future. These predictions serve as a mechanism for integrating incoming information and updating the narrative model through prediction error, without completely eliminating past versions. We define this process as having three aspects: (1) constrained expectations, (2) preference projection, and (3) causal extrapolation. Constrained expectations and preference projections respectively create the bounds and subjective desires for a narrative’s progress, while causal extrapolation builds, reworks, and maintains the potential models for understanding the narrative. We offer multiversionality as a novel framework for thinking about narrative, social cognition, and decision making that presents adaptive benefits and future directions for empirical study. (shrink)

In his new book "The Importance of Being Rational", Errol Lord aims to give a real definition of the property of rationality in terms of normative reasons. If he can do so, his work is an important step towards a defense of ‘reasons fundamentalism’ – the thesis that all complex normative properties can be analyzed in terms of normative reasons. I focus on his analysis of epistemic rationality, which says that your doxastic attitudes are rational just in case they are (...) correct responses to the objective normative reasons you possess. For some fact to be an objective normative reason to do something that you possess, you have to be in a position to know this fact and be able to competently use it as a reason to do that thing. Lord’s view is thus a knowledge-first view about possessing normative reasons. Throughout the book, Lord conceptualizes belief in the traditional tripartite way – if you take any attitude at all towards a proposition, then you either believe it, or disbelieve it, or you suspend judgment about it. Lord doesn’t discuss cases in which we’re uncertain. Yet, those cases are ubiquitous. I explore how his view can be extended to them. I first discuss whether his strategy for vindicating coherence requirements in terms of normative reasons can be applied to credences. I then ask how Lord can conceive of the doxastic attitudes that encode uncertainty . (shrink)

In this article, I discuss three distinct but related puzzles involving lotteries: Kyburg’s lottery paradox, the statistical evidence problem, and the Harman-Vogel paradox. Kyburg’s lottery paradox is the following well-known problem: if we identify rational outright belief with a rational credence above a threshold, we seem to be forced to admit either that one can have inconsistent rational beliefs, or that one cannot rationally believe anything one is not certain of. The statistical evidence problem arises from the observation that people (...) seem to resist forming outright beliefs whenever the available evidence for the claim under consideration is purely statistical. We need explanations of whether it is in fact irrational to form such beliefs, and of whether a clear distinction can be drawn between statistical and non-statistical evidence. The Harman-Vogel paradox is usually presented as a paradox about knowledge: we tend to assume that we can know so-called ordinary propositions, such as the claim that I will be in Barcelona next spring. Yet, we hesitate to make knowledge claims regarding so-called lottery propositions, such as the claim that I won’t die in a car crash in the next few months, even if these lottery propositions are obviously entailed by the ordinary propositions we claim to know. Depending on one’s view about the relationship between rational belief and knowledge, the Harman-Vogel paradox has ramifications for a theory of rational outright belief. Formal theories of the relationship between rational credence and rational belief, such as Leitgeb’s stability theory, tend to focus mostly on handling Kyburg’s lottery paradox, but not the other two puzzles I mention. My aim in this article is to draw out relationships and differences between the puzzles, and to examine to what extent existing formal solutions to Kyburg’s lottery paradox help with answering the statistical evidence problem and the Harman-Vogel paradox. (shrink)

Special Issue, n. I, ch. 1, On the Transcendental.

What attitudes can we rationally take towards our philosophical views? In this paper, I offer a novel answer to this question that draws on the distinction between transitional and terminal attitudes (Staffel 2019). Terminal attitudes are the kinds of attitudes, such as beliefs and credences, that we form as conclusions of reasoning processes. Transitional attitudes, by contrast, are attitudes we form during ongoing deliberations, before we settle on an opinion about how our information bears on the question of interest. I (...) argue that we can rationally hold terminal attitudes towards local philosophical claims, but not global ones. Only transitional attitudes can be rationally held towards global philosophical claims, at least in most cases. (shrink)

This study examined people’s ability to predict and postdict their performance on an event-based prospective memory task. Using nonfocal cues, one group of participants predicted their success at finding animal words and a different group predicted their ability to find words with a particular syllable in it. The authors also administered a self-report questionnaire on everyday prospective and retrospective memory failures. Based on the different strategies adopted by the two groups and correlations among the dependent variables, the authors concluded that (...) people do have a basic awareness of their prospective memory abilities, but that this awareness is far from accurate. The importance of metamemory concerning one’s prospective memory is discussed in terms of how it influences the strategies that people might choose for actually completing their various everyday intentions. (shrink)

We argue that the evolutionary function of reasoning is to allow us to secure more accurate beliefs and more effective intentions through collective deliberation. This sets our view apart both from traditional intellectualist accounts, which take the evolutionary function to be individual deliberation, and from interactionist accounts such as the one proposed by Mercier and Sperber, which agrees that the function of reasoning is collective but holds that it aims to disseminate, rather than come up with, accurate beliefs. We argue (...) that our collectivized intellectualism offers the best explanation of the range of biases that human reasoning is prone to, and that it does better than interactionism at offering a function of reasoning that would have been adaptive for our distant ancestors who first evolved this capacity. (shrink)

This entry provides an overview of the current state of the debate between epistemic permissivists and impermissivists. Three important choice points for the permissivist are identified, and implications are discussed for plausibility of the resulting versions of permissivism.

Julia Annas; XII*—How Basic are Basic Actions?, Proceedings of the Aristotelian Society, Volume 78, Issue 1, 1 June 1978, Pages 195–214, https://doi.org/10.1093.

Bayesian epistemology provides a popular and powerful framework for modeling rational norms on credences, including how rational agents should respond to evidence. The framework is built on the assumption that ideally rational agents have credences, or degrees of belief, that are representable by numbers that obey the axioms of probability. From there, further constraints are proposed regarding which credence assignments are rationally permissible, and how rational agents’ credences should change upon learning new evidence. While the details are hotly disputed, all (...) flavors of Bayesianism purport to give us norms of ideal rationality. This raises the question of how exactly these norms apply to you and me, since perfect compliance with those ideal norms is out of reach for human thinkers. A common response is that Bayesian norms are ideals that human reasoners are supposed to approximate – the closer they come to being ideally rational, the better. To make this claim plausible, we need to make it more precise. In what sense is it better to be closer to ideally rational, and what is an appropriate measure of such closeness? This article sketches some possible answers to these questions. (shrink)

Background: COVID-19 pandemic has led to heightened moral distress among healthcare providers. Despite evidence of gendered differences in experiences, there is limited feminist analysis of moral distress. Objectives: To identify types of moral distress among women healthcare providers during the COVID-19 pandemic; to explore how feminist political economy might be integrated into the study of moral distress. Research Design: This research draws on interviews and focus groups, the transcripts of which were analyzed using framework analysis. Research Participants and Context: 88 (...) healthcare providers, based in British Columbia Canada, participated virtually. Ethical Considerations: The study received ethical approval from Simon Fraser University. Findings: Healthcare providers experienced moral dilemmas related to ability to provide quality and compassionate care while maintaining COVID-19 protocols. Moral constraints were exacerbated by staffing shortages and lack of access to PPE. Moral conflicts emerged when women tried to engage decision-makers to improve care, and moral uncertainty resulted from lack of clear and consistent information. At home, women experienced moral constraints related to inability to support children’s education and wellbeing. Moral conflicts related to lack of flexible work environments and moral dilemmas developed between unpaid care responsibilities and COVID-19 risks. Women healthcare providers resisted moral residue and structural constraints by organizing for better working conditions, childcare, and access to PPE, engaging mental health support and drawing on professional pride. Discussion: COVID-19 has led to new and heightened experiences of moral distress among HCP in response to both paid and unpaid care work. While many of the experiences of moral distress at work were not explicitly gendered, implicit gender norms structured moral events. Women HCP had to take it upon themselves to organize, seek out resources, and resist moral residue. Conclusion: A feminist political economy lens illuminates how women healthcare providers faced and resisted a double layering of moral distress during the pandemic. (shrink)

Until relatively recently, researchers believed that synaesthetic sensations and their triggers were arbitrarily paired, and entirely idiosyncratic from one synaesthete to the next. Put differently, they believed that no two synaesthetes would have similar experiences from the same set of triggers, unless this had occurred by chance. This position likely arose because, prior to the internet, it was extremely difficult to recruit more than a small handful of synaesthete participants, and on the surface, synaesthetes do tend to disagree on their (...) associations when compared one-on-one. However, recent advances in communication have allowed researchers access to far larger groups of synaesthete participants, and this has changed our opinion about how similar synaesthetes might in fact be. A dedicated body of research has now shown that synaesthetic associations are built, to some extent, on a set of unconscious 'rules', shared across synaesthetes. These rules dictate the choice of sensation for certain triggers, and allow us to see patterns emerging which, although not absolute, provide a type of coherence across synaesthetes as a whole. I shall also show that some of these underlying rules operate in the population at large, to allow all individuals to make intuitive pairings across the senses. This chapter describes some of these rules, across a range of different modalities, and across different variants of synaesthesia. (shrink)

Trust and corporation (extracts) / by F.W. Maitland -- Respublica Christiana -- by J.N. Figgis -- Society and state / by R.M. MacIver -- The discredited state / by E. Barker -- Conflicting social obligations / by G.D.H. Cole -- Community is a process / by M.P. Follett -- The eruption of the group / by E. Barker -- The masses in a representative democracy / by M. Oakeshott -- The atavism of social justice / by F.A. von Hayek -- (...) Collective entities and moral rights / by V. van Dyke -- Capitalism, citizenship and community / by S. Macedo -- Liberalism and the politicization of ethnicity / by W. Kymlicka -- Are there any cultural rights? / by C. Kukathas -- The civil society argument / by M. Walzer. (shrink)