Injection of a peptide of 36 amino acids into virgin Drosophila females changes their reproductive properties drastically: males are rejected and egg laying is increased. The neuronal and physiological properties of the virgin state are replaced by a new pattern of behavior and stimulation of egg production and deposition. Under natural conditions, the peptide is synthesized by the male and transferred into the female during copulation. The sex‐peptide, therefore, can be considered as a pheromone. In this review, I shall limit (...) my discussion to Drosophila melanogaster. (shrink)

Gadamer's book extends and codifies the main hermeneutical concepts of Bultmann, Heidegger, and their adherents, and can be considered a summa of what Robinson calls "The New Hermeneutic." By Robinson and other theologians, and by Continental literary critics, Wahrheit und Methode has been welcomed as a philosophical justification for "vital and relevant" interpretations that are unencumbered by a concern for the author's original intention. On this point "The New Hermeneutic" reveals its affinities with "The New Criticism" and the newer "Myth (...) Criticism." All three have impugned the author's prerogative to be the determiner of textual meaning. Gadamer, however, grounds his anti-intentionalism only partially in aesthetics and not at all in the collective unconscious but primarily in the radical historicism of Martin Heidegger. (shrink)

Ecological restoration has been a topic for philosophical criticism for three decades. In this essay, I present a discussion of the arguments against ecological restoration and the objections raised against my position. I have two purposes in mind: to defend my views against my critics, and to demonstrate that the debate over restoration reveals fundamental ideas about the meaning of nature, ideas that are necessary for the existence of any substantive environmentalism. I discuss the possibility of positive restorations, the idea (...) that nature can restore itself, the meaning of artifacts, and the significance of the distinction between humanity and nature. (shrink)

Humans have long been characterized as poor probabilistic reasoners when presented with explicit numerical information. Bayesian word problems provide a well-known example of this, where even highly educated and cognitively skilled individuals fail to adhere to mathematical norms. It is widely agreed that natural frequencies can facilitate Bayesian reasoning relative to normalized formats (e.g. probabilities, percentages), both by clarifying logical set-subset relations and by simplifying numerical calculations. Nevertheless, between-study performance on “transparent” Bayesian problems varies widely, and generally remains rather unimpressive. (...) We suggest there has been an over-focus on this representational facilitator (i.e. transparent problem structures) at the expense of the specific logical and numerical processing requirements and the corresponding individual abilities and skills necessary for providing Bayesian-like output given specific verbal and numerical input. We further suggest that understanding this task-individual pair could benefit from considerations from the literature on mathematical cognition, which emphasizes text comprehension and problem solving, along with contributions of online executive working memory, metacognitive regulation, and relevant stored knowledge and skills. We conclude by offering avenues for future research aimed at identifying the stages in problem solving at which correct versus incorrect reasoners depart, and how individual difference might influence this time point. (shrink)

This paper investigates the historical origins of the notion of incommensurability in contemporary philosophy of science. The aim is not to establish claims of priority, but to enhance our understanding of the notion by illuminating the various issues that contributed to its development. Kuhn developed his notion of incommensurability primarily under the influence of Fleck, Polanyi, and Köhler. Feyerabend, who had developed his notion more than a decade earlier, drew directly from Duhem, who had developed a notion of incommensurability in (...) 1906. The idea is that in the course of scientific advance, when fundamental theories change, meanings change, which can result in a new conception of the nature of reality. Feyerabend repeatedly used this notion of incommensurability to attack various forms of conceptual conservativism. These include the logical positivists’ foundational use of protocol statements, Heisenberg’s methodological principle that established results must be presupposed by all further research, attempts to separate philosophical accounts of ontology from physics, Bohr’s principle of complementarity, and logical empiricist accounts of reduction and explanation. Focusing on the function of the notion of incommensurability common to Feyerabend’s various critiques explicates Feyerabend’s early philosophy as a series of challenges to forms of conceptual conservativism.Keywords: Incommensurability ; Paul Feyerabend; Thomas Kuhn; Pierre Duhem; Wolfgang Köhler; Ludwik Fleck. (shrink)

Written in 1839 and chosen as the winning entry in a competition held by the Royal Norwegian Society of Sciences, Schopenhauer's Prize Essay on the Freedom of the Will marked the beginning of its author's public recognition and is widely regarded as one of the most brilliant and elegant treatments of free will and determinism. Schopenhauer distinguishes the freedom of acting from the freedom of willing, affirming the former while denying the latter. He portrays human action as thoroughly determined but (...) also argues that the freedom which cannot be established in the sphere of human action is preserved at the level of our innermost being as individuated will, whose reality transcends all dependency on outside factors. This volume offers the text in a previously unpublished translation by Eric F. J. Payne, the leading twentieth-century translator of Schopenhauer into English, together with a historical and philosophical introduction by Günter Zöller. (shrink)

I examine challenges to images of a personal god definitive for normatively policed theism (often called “traditional theism”), questioning whether a subject can be conscious of a transcendent being. I examine the challenges to show that disappointment with such images calls for rethinking terms like “transcendence” in horizontal rather than vertical registers. Through this, I indicate an irony in yearning for transcendence, one in which there is movement toward—rather than beyond—the utterly ordinary. We will see that such un-extra-ordinary transcendence makes (...) a difference once difference is no longer determined under the hegemony of what Levinas calls “the atheistic I.” I bring together resources from feminist philosophies and Asian religions both to elaborate on the nature of the atheistic I and to rehabilitate a redeeming appreciation of the ordinary. My hope is to ameliorate disempowered estrangement by indicating ways the ordinary generates, not inhibits, becoming. However, my broader intent is to contribute to shifting sands in contemporary philosophy of religion due to recent calls for diversifying the field by including multiple religions, questioning the centrality of belief, and engaging multiple methods relevant in religious studies. (shrink)

This article contributes to philosophical reflections on public health law by drawing on virtue jurisprudence, which rests on the straightforward observation that a political community and its laws will inevitably shape the character of its officials and subjects, and that an excellent character is indispensable to fulfilment. Thus, the law is properly set to encourage virtue and discourage vice. This opens a new perspective onto the ultimate purpose of public health law that is human flourishing. The means of pursuing this (...) end is to entrust public health powers to officials to virtuously serve the common good, of which population health is one of its most important constituents, within the bounds of the law of the land. This article calls for the adoption of a Prudent Public Health Official standard into the law, in order to cultivate prudent, just, courageous and temperate characters in officialdom. Interestingly, this standard already chimes with certain pre-existing core principles of public health judicial doctrine in the USA, the European Union and the UK. (shrink)

Holistic accounts of the natural environment in environmental ethics fail to stress the distinction between the concepts of comnlunity and organism. Aldo Leopold’s “Land Ethic” adds to this confusion, for it can be interpreted as promoting either a community or an organic model of nature. The difference between the two concepts lies in the degree of autonomy possessed by constituent entities within the holistic system. Members within a community are autonomous, while the parts of an organism are not. Different moral (...) conclusions and environmental policies may result from this theoretical distinction. Treating natural entities as parts of an organism downgrades their intrinsic value as individual natural beings, since the only relevant moral criterion in an organic environmental ethic is the instrumental value that each natural entity has for the system. This ethic allows instances of the “substitution problem”-the replacement of one entity in an ecosystem by another provided that the overall functioning of the system is notharmed. However, since substitution violates environmentalist principles, for example, calling for respect for the integrity of the entities in a natural system, an organic environmental ethic must be rejected. A community model focuses on both the functional value and the autonomous intrinsie value of natural entities in a system. A community environmental ethic thus avoids the substitution problem. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Human Genome Project and BioethicsEric T. Juengst, Ph.D. (bio)The fifteen-year "human genome project" at the National Institutes of Health and the Department of Energy officially began on October 1, 1990. With it began a new dimension in federally supported scientific research: concurrent funding for work to anticipate the social consequences of the project's research and to develop policies to guide the use of the knowledge it produces. As (...) a result, the National Center for Human Genome Research (NCHGR) at NIH will support the largest public investment in bioethical analysis to date.NCHGR was established to work with other federal, private, and international organizations on the scientific effort to characterize the form and content of the human genome. The research will yield information—high-resolution genetic linkage and physical maps of all the human chromosomes as well as human DNA sequence data—that will be a resource for studies of gene structure and function. It will greatly increase our understanding of the genetic aspects of human health and disease. That increased understanding will eventually provide insights into the prevention and treatment of the 3,000 known inherited disorders, and of conditions caused by our (gene-governed) physiological reactions to pathogens, toxins, and mutagens of external origin.It has been clear since the conception of the human genome project, however, that professional and public deliberations concerning the responsible use of genetic information must be a part of the process. The most immediate consequence of genome research will be the development of new diagnostic and predictive tests, well in advance of corresponding therapeutic or curative advances. The implications of acquiring and using that knowledge about individuals raise policy questions at many levels within society. The primary purpose of the Ethical, Legal and Social Implications Program at the NCHGR is to anticipate and address these questions early in the life of the scientific project, to help optimize the [End Page 71] benefits to human welfare and opportunity from the new knowledge, and to guard against its misuses.The program has identified three sets of questions as particularly important to pursue as the genome initiative proceeds:1.Issues involved in the integration of new genetic tests into medical practice. Human genome research is expected to increase greatly the number of gene-based diagnostic and prognostic tests available to health professionals. The bioethical policy problems involved in integrating those tests effectively into medical practice include developing standards for:— accuracy and quality control of genetic tests;— medical indications for testing and design of testing protocols;— professional responsibilities of clinicians who perform tests;— confidentiality of information obtained from testing;— access to and use of test results by third parties, such as health insurers; and— reimbursement for testing and test-related counseling.These are problems for both those charged with regulating the use of new genetic tests and for those establishing the standards of practice within the health professions. Thus, in addition to soliciting and funding scholarly research proposals on both the factual and normative questions raised by these problems, the program is commissioning a major new study by the National Academy of Sciences/Institute of Medicine aimed at providing professional guidelines for the integration of genetic services into mainstream medical practice.2. Issues involved in educating and counseling individuals about genetic test results. The primary risk that health professionals will face in using genetic tests is the misinterpretation of their findings and the resulting potential for psychological trauma, stigmatization, and discrimination. Sometimes, out of ignorance, patients, families, and social institutions already stigmatize genetic disorders and treat those with them unfairly. This risk broadens as the genetic elements of more health problems are uncovered and gene-based tests for susceptibilities and carrier states are developed.To protect against these risks, NCHGR is soliciting and supporting projects aimed at improving professional and public understanding of these tests and their implications. For example, a philosopher is leading a team of geneticists and physicians in a scholarly effort to clarify [End Page 72] concepts of genetic susceptibility and draw out the social meaning of their different interpretations. Other projects involve social scientific studies of genetic risk perceptions, stigmatization, and discrimination. The conclusions of these studies, and... (shrink)

Paradise Understood: New Philosophical Essays about Heaven systematically investigates heaven, or paradise, as conceived within theistic religious traditions such as Rabbinic Judaism, Christianity, and Islam. It considers a variety of topics concerning what life in paradise would, could, or will be like for human persons. The collection offers novel approaches to questions about heaven of perennial philosophical interest, and breaks new ground by expanding the range of questions about heaven that philosophers have considered. The contributors wrestle with questions about human (...) life in paradise that span the spectrum of the major subfields of philosophical enquiry. By employing both historical and contemporary philosophical resources, the volume makes a pioneering contribution toward answering pressing questions about human life in paradise. It will serve as a platform for future research, reinvigorating philosophical investigation into these neglected topics within philosophy of religion. (shrink)

One of the important lessons to take away from Rohit Parikh’s impressive body of work is that logicians and computer scientists have much to gain by focusing their attention on the intricacies of political campaigns. Drawing on recent work developing a theory of expressive voting, we study the dynamics of voters’ opinions during an election. In this paper, we develop a model in which the relative importance of the different issues that concern a voter may change either in response to (...) candidates’ statements during a campaign or due to unforeseen events. We study how changes in a voter?s attention to the issues influence voting behavior under voting systems such as plurality rule and approval voting. We argue that it can be worthwhile for candidates to reshape public focus, but that doing so can be a complex and risky activity. (shrink)

ABSTRACT Why does post-truth discourse feel true? This article argues that post-truth fears the death of rhetoric, rather than truth, and traces that fear to the voluminous, rapid, and intense production of stasis on social media. Social media enable and weaponize the production of stasis, and that production generates affects more aligned with death than life (stagnation, hopelessness) that explain why post-truth feels true. These fears and their concomitant hopes constitute an affective economy also present in philosophy’s predominant images of (...) rhetoric. Some images picture rhetoric as movement, whereas others emphasize rhetoric’s capacity to secure the status quo. Social media beckon a supplementary image—a vortex—in which rhetorical movement functions to produce standstill. This image suggests the need to consider affects generated by rhetorical processes as much as from texts. Post-truth’s affective economy also drives stasis production generally, and scholars should attend to the affective economies driving various rhetorical modes. (shrink)

Buddhas, gods, prophets and oracles are often depicted as asking questions. But what are we to understand when Jesus asks “Who do you say that I am?”, or Mazu, the Classical Zen master asks, “Why do you seek outside?" Is their questioning a power or weakness? Is it something human beings are only capable of due to our finitude? Is there any kind of question that is a power? -/- Focusing on three case studies of questions in divine discourse on (...) the level of story - the god depicted in the Jewish Bible, the master Mazu in his recorded sayings literature, and Jesus as he is depicted in canonized Christian Gospels - Nathan Eric Dickman meditates on human responses to divine questions. He considers the purpose of interreligious dialogue and the provocative kind of questions that seem to purposefully decenter us, drawing on methods from confessionally-oriented hermeneutics and skills from critical thinking. -/- He allows us to see alternative ways of interpreting religious texts through approaches that look beyond reading a text for the improvement of our own religion or for access to some metaphysically transcendent reality. This is the first step in a phenomenology of religions that is inclusive, diverse, relevant and grounded in the world we live in. (shrink)

abstract: Numerous authors have compared Process thought as articulated by Alfred North Whitehead and Mahayana Buddhist philosophy, owing to the fact that each of these systems is rooted in the notion that relational action, rather than substance, is meta-physically fundamental and that human life is to be understood as fundamentally experiential. However, despite the fact that the foundational philosophical tenets of Mahayana Buddhism are built on axioms established and rooted in early Buddhism, relatively little has been written comparing Process thought (...) with the philosophy of early Buddhism. In this essay, I first offer a brief comparison and discussion of the foundational metaphysical principles of these systems. The purpose of this essay is to extend the dialogue between Process thought and early Buddhism, highlighting both areas of convergence and points of departure. The first task is to establish how key terms in each system may be understood in terms of the other and to point out ways in which these systems converge around questions of ontology, agency, and the nature of the self. I will then discuss the epistemologies that underwrite these meta-physical commitments. Finally, I will conclude with a brief comparison of the role of aesthetics in human experience and the soteriological project within these two schools of thought. (shrink)

We show how the notion of full Frobenius group of finite Morley rank generalizes that of bad group, and how it seems to be more appropriate when we consider the possible existence (still unknown) of nonalgebraic simple groups of finite Morley rank of a certain type, notably with no involution. We also show how these groups appear as a major obstacle in the analysis of FT-groups, if one tries to extend the Feit-Thompson theorem to groups of finite Morley rank.

Individual-level research in behavioral science can have massive impact and create system-level changes, as several recent mandates and other policy actions have shown. Although not every nudge creates long-term behavior change, defaults and other forms of choice architecture can not only change individual behavior but also reduce inequities and lead to changes in public policy and norms.

A recent article in Neuroethics posited “bad news for conservatives,” on the basis of survey data collected on line. On the basis of bivariate correlations between self-reported conservatism/liberalism and a variety of moral propositions, the author inferred that those moral judgments were ‘conservative’ or ‘liberal.’ Then, based on a series of bivariate correlations between those same moral propositions and measures of “morally worrisome” personality characteristics, the author concluded that conservatives tended to have these morally worrisome characteristics. Unfortunately, the original article (...) was replete with methodological and statistical errors. This paper presents a reanalysis of the data from the original article, using good statistical and methodological technique. The reanalysis suggests that there are some small but potentially theoretically meaningful relationships between some moral propositions and three morally worrisome (antisocial) personality characteristics. The data also suggest that these relationships can change substantially depending on other conditions, so should not yet be generalized. (shrink)

The political philosopher Hannah Arendt actively engaged in the problem of a Jewish homeland and the politics of Zionism in the years 1941–1948. She advocated a Binational solution to Palestine – a single political commonwealth with two national identities, Jewish and Arab, integrated in a federation with other countries in the region. In the crucial period leading up to the establishment of the State of Israel, Arendt became increasingly disillusioned with the Jewish Agency and the Zionist movement for failing to (...) organize a Jewish response to Nazism (a Jewish Army) and rejecting the Palestinian right to a homeland. (shrink)

ABSTRACTAt the end of 2016, Taiwan witnessed a string of massive protest demonstrations held by both ends of the ideological debate on marriage equality. These public demonstrations can be seen as...

The cell division and differentiation events that occur during the development of the nematode Caenorhabditis elegans are nearly identical between different individuals, a feature that distinguishes this organism from larger and more complex metazoans, such as humans and Drosophila. In view of this discrepancy, it might be expected that the regulation of cell growth, division and differentiation in C. elegans would involve mechanisms separate from those utilized in larger animals. However, the results of recent genetic, molecular and cellular studies indicate (...) that C. elegans employs an arsenal of developmental regulatory mechanisms quite similar to those wielded by its arthropod and vertebrate relatives. Thus, the nematode system is providing both novel and complementary insights into the general problem of how growth and patterning events are integrated in development. This review offers a general perspective on the regulation of cell division and growth in C. elegans, emphasizing recent studies of these crucial aspects of development. BioEssays 24:38–53, 2002. © 2002 John Wiley & Sons, Inc. (shrink)

Testing the other. It is nowadays a commonplace of academic discourse on social sciences, especially when it comes to such disciplines as anthropology and semiotics, to oppose the old (and old-fashioned) methods of the “structuralists” to post-modern and post-structural epistemological attitudes. Structuralism, it is said, was based on the idea that it is possible to apprehend the meaning of cultural productions from an exterior and therefore objective standpoint, just by making explicit their immanent principles of organization. Today, on the contrary, (...) a totally distinct approach of cultural productions would stem from the consciousness of a strict interdependence, or even of an identity in nature between subject and object at all levels of the process of knowledge, at least in the area of the humanities. However, such a crude opposition proves insufficient when one observes the effective practices of current research. The example here analysed is the account given by the American anthropologist Paul Rabinow of his first mission abroad: Reflections on Fieldwork in Morocco. The analysis, based on the use of a semiotic modelling of interaction, consists in exploring the variety of positions respectively adopted by the anthropologist and his informants according to circumstances and contexts. Four regimes are in principle distinguishable: programmation, based on regularity and predictability of the actors’ behaviour, manipulation, based on some kind of contractualization of their relationships, adjustment, based upon reciprocal sensitivity and various strategies permitting to both partners of the interaction to test one another, and a regime of consent to the unexpected or the unforeseeable. The main result of the analysis resides in the possibility of showing that at each of these styles of pragmatic interaction corresponds a specific regime at the cognitive level as well. This leads tostressing the complexity, if not heterogeneity, of the strategies of knowledge involved at various stages of anthropological research, from the collection ofdata to the cooperative production of new forms of understanding. Taking the risk of generalization, one might also consider the interactional device, which ishere tested through the reading of P. Rabinow’s report as a metatheoretical model describing the various epistemological stances at work and at stake in thepractices of research in social sciences at large. (shrink)