When you gaze out at the night sky with its awe-inspiring display of stars and galaxies, do you ever ask yourself if it could be possible that you are actually looking into a mirror? What if we inhabit a universe that perfectly fits our needs here on Earth -- a truly human universe? That's the bold thesis author Deepak Chopra and physicist Menas Kafatos set out to prove: quite literally, "You are the universe." The startling truth is that the (...) everyday world of physical objects "out there" disguises a hidden dimension. By turning our investigation "in here" to the world of consciousness, the real reality emerges. You Are the Universe guides the reader into a realm in which each of us has the power to transform our personal existence, while at the same time fashioning a new story about how time, space, matter, and energy came into existence. Looking to overturn the traditional model of scientific reality, Chopra and Kafatos hold that each of us is a cocreator of reality and we can uncover the hidden dimensions where consciousness is a field of infinite possibilities. This seemingly impossible proposition follows from the cutting-edge modern thinking of the quantum universe and the great mysteries that must be unriddled before human beings actually know who they are. These include but are not limited to questions such as What came before the big bang? Why does the universe fit together so perfectly? Where did time come from? And do we live in a conscious universe? These mysteries are part and parcel of everyone's life. "All of us live in a participatory universe," the authors write. "Once you decide that you want to participate fully with mind, body, and soul, the paradigm shift becomes personal. The reality you inhabit will be yours to either embrace or change. (shrink)

In a paper entitled ‘Saints and Heroes’ 1 Professor J. O. Urmson has criticised ‘the trichotomy of duties, indifferent actions, and wrongdoing’ , commonly found in moral philosophy, on the ground that it fails to cover an important class of actions, of which saintly and heroic actions are ‘conspicuous” but by no means the only examples. I am inclined to think that this trichotomy is defensible, and that at least it deserves a much longer run for its money than Urmson (...) gives it. The form in which he presents it, however, makes it more implausible than it need be and this is perhaps the main reason why he finds it so indefensible. (shrink)

Chopra and Weiss address perhaps the fundamental issue in international relations today: the sacrosanct sets of sovereignty. The word "sovereignty" explains why the international community has difficulty countering human rights violations.

We provide a formal study of belief retraction operators that do not necessarily satisfy the postulate. Our intuition is that a rational description of belief change must do justice to cases in which dropping a belief can lead to the inclusion, or ‘liberation’, of others in an agent's corpus. We provide two models of liberation via retraction operators: ρ-liberation and linear liberation. We show that the class of ρ-liberation operators is included in the class of linear ones and provide axiomatic (...) characterisations for each class. We show how any retraction operator can be ‘converted’ into either a withdrawal operator ) or a revision operator via the Harper Identity and the Levi Identity respectively. (shrink)

Although J. S. Mill′s essay On Liberty was intended by its author to be read as a self-contained work, 1 and even though a careful reading would justify seeing it in this way, it has far too often been denied this right even by its defenders. There is a crucial distinction to be made between eliciting some point of substance from a particular work by an author and then turning to the rest of his work to throw further light on (...) it, and employing other texts from the corpus of his writings to put the construction on certain things said in it which the work by itself cannot sustain, thus treating the former as essentially a fragment, albeit a most important fragment, of a whole. 2 I would suggest that recourse to the latter course is justified only when the possibilities of treating it autarchically have already been explored. In this paper I propose to treat a celebrated text in the former way only because I believe that the results will show such an approach to be uniquely worthwhile, or at least fruitful enough to justify a paper conceived in this way. And, with a view to putting what I want to say about it in maximum focus I shall with one or two exceptions eschew giving supporting evidence from Mill′s other writings, even when this is permitted by the distinction I have made in this opening paragraph. (shrink)

Traditional accounts of belief change have been criticized for placing undue emphasis on the new belief provided as input. A recent proposal to address such issues is a framework for non-prioritized belief change based on default theories (Ghose and Goebel, 1998). A novel feature of this approach is the introduction of disbeliefs alongside beliefs which allows for a view of belief contraction as independently useful, instead of just being seen as an intermediate step in the process of belief revision. This (...) approach is, however, restrictive in assuming a linear ordering of reliability on the received inputs. In this paper, we replace the linear ordering with a preference ranking on inputs from which a total preorder on inputs can be induced. This extension brings along with it the problem of dealing with inputs of equal rank. We provide a semantic solution to this problem which contains, as a special case, AGM belief change on closed theories. (shrink)

The axiom of recovery, while capturing a central intuition regarding belief change, has been the source of much controversy. We argue briefly against putative counterexamples to the axiom—while agreeing that some of their insight deserves to be preserved—and present additional recovery-like axioms in a framework that uses epistemic states, which encode preferences, as the object of revisions. This makes iterated revision possible and renders explicit the connection between iterated belief change and the axiom of recovery. We provide a representation theorem (...) that connects the semantic conditions we impose on iterated revision and our additional syntactical properties. We show interesting similarities between our framework and that of Darwiche–Pearl (Artificial Intelligence 89:1–29 1997). In particular, we show that intuitions underlying the controversial (C2) postulate are captured by the recovery axiom and our recovery-like postulates (the latter can be seen as weakenings of (C2)). We present postulates for contraction, in the same spirit as the Darwiche–Pearl postulates for revision, and provide a theorem that connects our syntactic postulates with a set of semantic conditions. Lastly, we show a connection between the contraction postulates and a generalisation of the recovery axiom. (shrink)

Several authors have recently suggested that classic psychedelics might be safe and effective agents of moral enhancement. This raises the question: can we learn anything interesting about the nature of moral experience from a close examination of transformative psychedelic experiences? The interdisciplinary enterprise of philosophical psychopathology attempts to learn about the structure and function of the “ordinary” mind by studying the radically altered mind. By analogy, in this chapter we argue that we can gain knowledge about the everyday moral life (...) by studying extraordinary experiences of altered moral cognition and experience. We focus on a specific class of cases: experiences of forgiveness induced by psychedelics. We argue that close attention to such experiences reveals the importance of thought/emotion coherence and dissonance in the moral life and vindicates some heterodox ideas about moral phenomenology and psychology. (shrink)

We propose a new relevance sensitive model for representing and revising belief structures, which relies on a notion of partial language splitting and tolerates some amount of inconsistency while retaining classical logic. The model preserves an agent's ability to answer queries in a coherent way using Belnap's four-valued logic. Axioms analogous to the AGM axioms hold for this new model. The distinction between implicit and explicit beliefs is represented and psychologically plausible, computationally tractable procedures for query answering and belief..

We present a method for relevance sensitive non-monotonic inference from belief sequences which incorporates insights pertaining to prioritized inference and relevance sensitive, inconsistency tolerant belief revision. Our model uses a finite, logically open sequence of propositional formulas as a representation for beliefs and defines a notion of inference from maxiconsistent subsets of formulas guided by two orderings: a temporal sequencing and an ordering based on relevance relations between the putative conclusion and formulas in the sequence. The relevance relations are ternary (...) (using context as a parameter) as opposed to standard binary axiomatizations. The inference operation thus defined easily handles iterated revision by maintaining a revision history, blocks the derivation of inconsistent answers from a possibly inconsistent sequence and maintains the distinction between explicit and implicit beliefs. In doing so, it provides a finitely presented formalism and a plausible model of reasoning for automated agents. (shrink)

The standard theory for belief revision provides an elegant and powerful framework for reasoning about how a rational agent should change its beliefs when confronted with new information. However, the agents considered are extremely idealized. Some recent models attempt to tackle the problem of plausible belief revision by adding structure to the belief bases and using nonstandard inference operations. One of the key ideas is that not all of an agent's beliefs are relevant for an operation of belief change.In this (...) paper we incorporate the insights pertaining to local change and relevance sensitivity with the use of approximate inference relations. These approximate inference relations offer us partial solutions at any stage of the revision process. The quality of the approximations improves as we allow for more and more resources to be used. We are provided with upper and lower bounds to what would be obtained with the use of classical inference. (shrink)

In a paper entitled ‘Saints and Heroes’1 Professor J. O. Urmson has criticised ‘the trichotomy of duties, indifferent actions, and wrongdoing’, commonly found in moral philosophy, on the ground that it fails to cover an important class of actions, of which saintly and heroic actions are ‘conspicuous” but by no means the only examples. I am inclined to think that this trichotomy is defensible, and that at least it deserves a much longer run for its money than Urmson gives it. (...) The form in which he presents it, however, makes it more implausible than it need be and this is perhaps the main reason why he finds it so indefensible. (shrink)

Edited by David Rondel and Samir Chopra, The Moral Psychology of Anxiety presents new work on the causes, consequences, and value of anxiety. Straddling philosophy, psychology, clinical medicine, history, and other disciplines, the chapters in this volume explore anxiety from an impressively wide range of perspectives. The first part is more historical, exploring the meaning of anxiety in different philosophical traditions and historical periods, including ancient Chinese Confucianism, twentieth-century European existentialism, and the Roman Stoics. The second part focuses on (...) a cluster of questions having to do with anxiety’s nature and significance: Is anxiety something biological or cultural, or perhaps both? What is at the root of anxiety? Why should human beings suffer in this way? What is the experience of anxiety like, and what, if anything, are the benefits associated with it? Does anxiety have the potential to make us more virtuous or improve the quality of our inquiry? Addressing an area where newer work in moral psychology is sorely needed, this collection and the varied perspectives it offers will be of great interest to scholars, professionals, and students across philosophy, psychology, and related fields. (shrink)

Possible-world semantics are provided for Parikh’s relevance-sensitive model for belief revision. Having Grove’s system-of-spheres construction as a base, we consider additional constraints on measuring distance between possible worlds, and we prove that, in the presence of the AGM postulates, these constraints characterize precisely Parikh’s axiom (P). These additional constraints essentially generalize a criterion of similarity that predates axiom (P) and was originally introduced in the context of Reasoning about Action. A by-product of our study is the identification of two possible (...) readings of Parikh’s axiom (P), which we call the strong and the weak versions of the axiom. An interesting feature of the strong version is that, unlike classical AGM belief revision, it makes associations between the revision policies of different theories. (shrink)

Routledge (New Media and Cyberculture Series), July 2007.

In lieu of an abstract, here is a brief excerpt of the content:Am I the Bad Guy?Tavishi ChopraWhat do you do when the 6-year-old patient you have vowed to protect suddenly deems you the bad guy?The afternoon started out like any typical afternoon during my inpatient pediatric rotation. We had finished rounding, grabbed lunch, and began to see our new admits. My residents told me to go see a 6-year-old, Ela, in the ED. All I knew was that she had (...) a burn injury. As I walked to her ED room, my heart sank.Burns from cigarette stumps covered her torso and back. She was holding her shirt off her chest to prevent the excruciating pain caused by her t-shirt rubbing against her skin. As soon as Ela made eye contact with me, she immediately started crying and exclaiming, "Mommy didn't mean to!" confirming exactly what I thought. These burns were inflicted from someone she loved.Ela was eventually admitted into the hospital, and the Department of Child Services was contacted. Little did I know that I would be so conflicted by this decision.DCS launched an investigation on Ela's mom, but during the investigation, Ela's mom was permitted at her bedside. It was very clear that Ela felt protected and loved by her mom. Often it was only her mom who could get her to stop crying during the painful dressing changes. I felt torn allowing Ela's mom to have such a strong presence in Ela's hospital stay. To me, nothing in the world can justify hurting a child so cruelly, and inflicting that pain so many times. However, my job was to help Ela heal. That meant that because Ela turned to her mom for support, I also needed to include Ela's mom in our medical decisions. I buried away any negative feelings I had, and I proceeded to interact with Ela's mom in a professional manner.It was this that allowed me to get to understand Ela's mom a little bit more. She was a single mom [End Page E8] working multiple jobs to help keep her family afloat. She often lived her day on three to four hours of sleep, so she was very tired. The sleep deprivation made her frustrated more easily, and she didn't have a healthy outlet to release her emotions. Unfortunately, Ela was on the receiving end of that frustration.Hearing her story made me even more angry, confused, and upset that a child suffered. I strongly believed that as adults, we should have better control of our emotions, and sleep deprivation and frustration weren't an excuse. I couldn't find it in me to respect Ela's mom, who I shamefully began to avoid.I still wanted to bond with Ela and show her unconditional love. When Ela's mom was at work, I would use that opportunity to go and spend time with her. We would play "princesses," blow bubbles together, and turn dressing changes into a game. We formed a special bond, and I always made it a goal to go and spend some time with her every day.DCS, meanwhile, was actively conducting an investigation. They interviewed Ela's mom, Ela's siblings, and Ela. The findings of their investigation revealed that Ela's mom often would lose her temper, and the kids feared their mom. Hearing this further proved to me that I did not need to interact with Ela's mom. Embarrassingly, it was just as much a priority for me to avoid Ela's mom as it was to spend time with Ela.DCS eventually concluded that Ela's mom would lose custody of Ela for the time being. Because of the connection that Ela and I had, I took it upon myself to deliver the news to her. Our bond was shattered right then and there. She immediately began to cry, told me she hated me, and asked me to leave the room. Anytime I would go into her room after that, she would start screaming and refused to talk to me. In a span of five minutes, Ela's mom made a decision that destroyed their family... (shrink)

Y. N. Chopra; VIII—The Consequences of Human Actions, Proceedings of the Aristotelian Society, Volume 65, Issue 1, 1 June 1965, Pages 147–166, https://doi.org/1.

Today, anxiety is usually thought of as a pathology, the most diagnosed and medicated of all psychological disorders. But anxiety isn't always or only a medical condition. Indeed, many philosophers argue that anxiety is a normal, even essential, part of being human, and that coming to terms with this fact is potentially transformative, allowing us to live more meaningful lives by giving us a richer understanding of ourselves. In Anxiety, Samir Chopra explores valuable insights about anxiety offered by ancient (...) and modern philosophies-Buddhism, existentialism, psychoanalysis, and critical theory. Blending memoir and philosophy, he also tells how serious anxiety has affected his own life-and how philosophy has helped him cope with it. Chopra shows that many philosophers-including the Buddha, Kierkegaard, Nietzsche, Freud, and Heidegger-view anxiety as an inevitable human response to existence: to be is to be anxious. Drawing on Karl Marx and Herbert Marcuse, Chopra examines how poverty and other material conditions can make anxiety worse, but he emphasizes that not even the rich can escape it. Nor can the medicated. Inseparable from the human condition, anxiety is indispensable for grasping it. Philosophy may not be able to cure anxiety but, by leading us to greater self-knowledge and self-acceptance, it may be able to make us less anxious about being anxious. Personal, poignant, and hopeful, Anxiety is a book for anyone who is curious about rethinking anxiety and learning why it might be a source not only of suffering but of insight. (shrink)

Disabled/“differently abled” persons by virtue of being human have the right to enjoy human rights to life, liberty, equality, security, and dignity. However, due to social indifference, psychological barriers, a limited definition of “disability” entitling protection of law, and a lack of proper data, disabled persons in India remain an invisible category. Although several laws exit to ensure their full and effective participation in society, they remain insufficient as they are primarily based on the government's discretion. At the same time, (...) whenever the judiciary finds an opportunity, it acts as a real protector of disabled persons, but it is not feasible to knock on the door of the judiciary for every request. Interestingly, various civil societies and human rights activists have occasionally asserted the rights of the disabled. However, unless the foundation stones of law are fortified, disabled persons cannot fully realize their rights. It is high time to enact effective laws, with timely implementation, to protect their interests and empower their capabilities that are based on a “rights-based approach” rather than on the charity, medical, or social approaches. Thus, the horizons of law must be expanded to provide a “human friendly environment” for all of the disabled to overcome the barriers that impair their development. (shrink)

Human rights are basic, inalienable, interdependent, and universally recognized rights that aresine qua nonfor existence and growth of any human to be his best. These human rights are to be enjoyed by all human beings by virtue of being human, irrespective of their limitations or disabilities; due to the stated reason, the rights of disabled people as a “group right” are recognized as a third-generation human right.

Claims about the potential of free software to reform the production and distribution of software are routinely countered by skepticism that the free software community fails to engage the pragmatic and economic ‘realities’ of a software industry. We argue to the contrary that contemporary business and economic trends definitively demonstrate the financial viability of an economy based on free software. But the argument for free software derives its true normative weight from social justice considerations: the evaluation of the basis for (...) a software economy should be guided by consideration of the social and cultural states which are the ultimate goals of any economic arrangement. That is, the software economy should be evaluated in light of its ability to provide justice. We conclude with a discussion of possible avenues for reform. (shrink)

Our freedoms in cyberspace are those granted by code and the protocols it implements. When man and machine interact, co-exist, and intermingle, cyberspace comes to interpenetrate the real world fully. In this cyborg world, software retains its regulatory role, becoming a language of interaction with our extended cyborg selves. The mediation of our extended selves by closed software threatens individual autonomy. We define a notion of freedom for software that does justice to our conception of it as language, sketching the (...) outlines of a social and political philosophy for a cyborg world. In a cyberspace underwritten by free software, political structures become contingent and flexible: the polity can choose to change the extent and character of its participation. The rejection of opaque power is an old anarchist ideal: free software, by making power transparent, carries the potential to place substantive restrictions on the regulatory power of cyborg government. (shrink)

Micro RNAs (miRNAs) have been shown to control many cellular processes including developmental timing in different organisms. The prediction that miRNAs are involved in regulating hox genes of flies and mouse is quite a recent idea and is supported by the finding that mir‐196 represses Hoxb8 gene expression. The non‐coding regions that encode these miRNAs are also conserved across species in the same way as other mechanisms that regulate expression of hox genes. On the contrary, until now no homeotic phenotype, (...) a hallmark of any hox gene mutation, had been associated with any hox miRNA. Recent work on bithorax complex miRNA (miR–iab‐4–5p) shows, for the first time, that miRNAs can lead to homeotic transformation. This miRNA regulates Ultrabithorax (Ubx) and results in the transformation of haltere to wing.1 This study unveils a new complexity and finesse to the regulation of hox gene expression pattern that is needed for determining the anteroposterior body axis in all bilaterians. BioEssays 28: 445–448, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

The “free” in “free software” refers to a cluster of four specific freedoms identified by the Free Software Definition. The first freedom, termed “Freedom Zero,” intends to protect the right of the user to deploy software in whatever fashion, towards whatever end, he or she sees fit. But software may be used to achieve ethically questionable ends. This highlights a tension in the provision of software freedoms: while the definition explicitly forbids direct restrictions on users’ freedoms, it does not address (...) other means by which software may indirectly restrict freedoms. In particular, ethically-inflected debate has featured prominently in the discussion of restrictions on digital rights management and privacy-violating code in version 3 of the GPL (GPLv3). The discussion of this proposed language revealed the spectrum of ethical positions and valuations held by members of the free software community. In our analysis, we will provide arguments for upholding Freedom Zero; we embed the problem of possible uses of software in the broader context of the uses of scientific knowledge, and go on to argue that the provision of Freedom Zero mitigates against too great a moral burden—of anticipating possible uses of software—being placed on the programmer and that, most importantly, it facilitates deliberative discourse in the free software community. (shrink)

Martha P. Nochimson _Screen Couple Chemistry: The Power of 2_ Austin: University of Texas Press, 2002 ISBN 0-292-75578-3 (hb) 0-292-75579-1 (pb) 394 pp.

Thinking about how the law might decide whether to extend legal personhood to artificial agents provides a valuable testbed for philosophical theories of mind. Further, philosophical and legal theorising about personhood for artificial agents can be mutually informing. We investigate two case studies, drawing on legal discussions of the status of artificial agents. The first looks at the doctrinal difficulties presented by the contracts entered into by artificial agents. We conclude that it is not necessary or desirable to postulate artificial (...) agents as legal persons in order to account for such contracts. The second looks at the potential for according sophisticated artificial agents with legal personality with attendant constitutional protections similar to those accorded to humans. We investigate the validity of attributes that have been suggested as pointers of personhood, and conclude that they will take their place within a broader matrix of pragmatic, philosophical and extra-legal concepts. (shrink)

This note is prompted by a re-reading of the late Professor J. L. Austin's British Academy Lecture of 1956 “Ifs and Cans” and Professor P. H. Nowell-Smith's rejoinder to it. Austin states his topic at the beginning, and though he re-formulates it more precisely later on, it will suffice for my purposes to quote the opening short paragraph. He asks: “Are cans constitutionally iffy? Whenever, that is, we say that we can do something, or could do something, or could have (...) done something, is there an if in the offing—suppressed, it may be, but due nevertheless to appear when we set out our sentence in full or when we give an explanation of its meaning?”. Towards the end of his lecture he states his conclusion concerning the issue, viz. determinism, which is usually prominent at least implicitly in our discussion of such questions, in the following terms: “Determinism, whatever it may be, may yet be the case, but at least it appears not consistent with what we ordinarily say and presumably think.”. (shrink)

Free and open source software is taking an increasingly significant role in our software infrastructure. Yet many questions still exist about whether a software economy based on FOSS would be viable. We argue that contemporary trends definitively demonstrate this viability. Claiming that an economy must be evaluated as much by the ends it brings about as by its size or vigor, we draw on widely accepted notions of redistributive justice to show the ethical superiority of a software economy based on (...) FOSS. (shrink)

Deborah Thomas _Reading Hollywood: Spaces and Meanings in American Film_ London: Wallflower Press, 2001 ISBN 1-903364-01-9 144 pp.

Although J. S. Mill′s essay On Liberty was intended by its author to be read as a self-contained work,1 and even though a careful reading would justify seeing it in this way, it has far too often been denied this right even by its defenders. There is a crucial distinction to be made between eliciting some point of substance from a particular work by an author and then turning to the rest of his work to throw further light on it, (...) and employing other texts from the corpus of his writings to put the construction on certain things said in it which the work by itself cannot sustain, thus treating the former as essentially a fragment, albeit a most important fragment, of a whole.2 I would suggest that recourse to the latter course is justified only when the possibilities of treating it autarchically have already been explored. In this paper I propose to treat a celebrated text in the former way only because I believe that the results will show such an approach to be uniquely worthwhile, or at least fruitful enough to justify a paper conceived in this way. And, with a view to putting what I want to say about it in maximum focus I shall with one or two exceptions eschew giving supporting evidence from Mill′s other writings, even when this is permitted by the distinction I have made in this opening paragraph. (shrink)

Online medical reference websites are utilized by health care providers to enhance their education and decision making. However, these resources may not adequately reveal pharmaceutical-author interactions and their potential conflicts of interest. This investigation: evaluates the correspondence of two well-utilized CoI databases: the Centers for Medicare and Medicaid Services Open Payments and ProPublica’s Dollars for Docs and quantifies CoIs among authors of a publicly available point of care clinical support website which is used to inform evidence-based medicine decisions. Two data (...) sources were used: the hundred most common drugs and the top fifty causes of death. These topics were entered into a freely available database. The authors were then input into CMSOP and PDD and compensation and number of payments were determined for 2013–2015. The subset of highly compensated authors that also reported “Nothing to disclose” were further examined. There was a high degree of similarity between CMSOP and PDD for compensation and payment number. The amount received was 1.4% higher in CMSOP than in PDD. The articles where the authors had received the greatest compensation were in neurology, oncology, and endocrinology. Two authors reporting “Nothing to disclose” received appreciable and potentially relevant compensation. CMSOP and PDD produced almost identical results. CoIs were common among authors but self-reporting may be an inadequate reporting mechanism. Recommendations are offered for improving the CoI transparency of pharmaceutical-author interactions in point-of-care electronic resources. (shrink)

Online medical reference websites are utilized by health care providers to enhance their education and decision making. However, these resources may not adequately reveal pharmaceutical-author interactions and their potential conflicts of interest. This investigation: evaluates the correspondence of two well-utilized CoI databases: the Centers for Medicare and Medicaid Services Open Payments and ProPublica’s Dollars for Docs and quantifies CoIs among authors of a publicly available point of care clinical support website which is used to inform evidence-based medicine decisions. Two data (...) sources were used: the hundred most common drugs and the top fifty causes of death. These topics were entered into a freely available database. The authors were then input into CMSOP and PDD and compensation and number of payments were determined for 2013–2015. The subset of highly compensated authors that also reported “Nothing to disclose” were further examined. There was a high degree of similarity between CMSOP and PDD for compensation and payment number. The amount received was 1.4% higher in CMSOP than in PDD. The articles where the authors had received the greatest compensation were in neurology, oncology, and endocrinology. Two authors reporting “Nothing to disclose” received appreciable and potentially relevant compensation. CMSOP and PDD produced almost identical results. CoIs were common among authors but self-reporting may be an inadequate reporting mechanism. Recommendations are offered for improving the CoI transparency of pharmaceutical-author interactions in point-of-care electronic resources. (shrink)

Online medical reference websites are utilized by health care providers to enhance their education and decision making. However, these resources may not adequately reveal pharmaceutical-author interactions and their potential conflicts of interest. This investigation: evaluates the correspondence of two well-utilized CoI databases: the Centers for Medicare and Medicaid Services Open Payments and ProPublica’s Dollars for Docs and quantifies CoIs among authors of a publicly available point of care clinical support website which is used to inform evidence-based medicine decisions. Two data (...) sources were used: the hundred most common drugs and the top fifty causes of death. These topics were entered into a freely available database. The authors were then input into CMSOP and PDD and compensation and number of payments were determined for 2013–2015. The subset of highly compensated authors that also reported “Nothing to disclose” were further examined. There was a high degree of similarity between CMSOP and PDD for compensation and payment number. The amount received was 1.4% higher in CMSOP than in PDD. The articles where the authors had received the greatest compensation were in neurology, oncology, and endocrinology. Two authors reporting “Nothing to disclose” received appreciable and potentially relevant compensation. CMSOP and PDD produced almost identical results. CoIs were common among authors but self-reporting may be an inadequate reporting mechanism. Recommendations are offered for improving the CoI transparency of pharmaceutical-author interactions in point-of-care electronic resources. (shrink)

Collaborative filtering recommender system (CFRS) plays a vital role in today’s e-commerce industry. CFRSs collect ratings from the users and predict recommendations for the targeted product. Conventionally, CFRS uses the user-product ratings to make recommendations. Often these user-product ratings are biased. The higher ratings are called push ratings (PRs) and the lower ratings are called nuke ratings (NRs). PRs and NRs are injected by factitious users with an intention either to aggravate or degrade the recommendations of a product. Hence, it (...) is necessary to investigate PRs or NRs and discard them. In this work, opinion mining approach is applied on textual reviews that are given by users for a product to detect the PRs and NRs. The work also examines the effect of PRs and NRs on the performance of CFRS by evaluating various measures such as precision, recall, F-measure and accuracy. (shrink)