Never before, in any anthology, have contemporary epistemologists and philosophers of language come together to address the single most neglected important issue at the confluence of these two branches of philosophy, namely: Can we know facts from reliable reports? Besides Hume's subversive discussion of miracles and the literature thereon, testimony has been bypassed by most Western philosophers; whereas in classical Indian theories of evidence and knowledge philosophical debates have raged for centuries about the status of word-generated knowledge. `Is the (...) response "I was told by an expert on the subject" as respectable as "I saw" or "I inferred" in answer to "How do you know?"' is a question answered in diverse and subtle ways by Buddhists, Vaisesikas and Naiyayikas. For the first time this book makes available the riches of those debates, translating from Sanskrit some contemporary Indian Pandits' reactions to Western analytic accounts of meaning and knowledge. For advanced undergraduates in philosophy, for researchers - in Australia, Asia, Europe or America - on epistemology, theory of meaning, Indian or comparative philosophy, as well as for specialists interested in this relatively fresh topic of knowledge transmission and epistemic dependence this book will be a feast. After its publication analytic philosophy and Indian philosophy will have no excuse for shunning each other. (shrink)

We investigated how people interpret conditionals and how stable their interpretation is over a long series of trials. Participants were shown the colored patterns on each side of a six-sided die, and were asked how sure they were that a conditional holds of the side landing upwards when the die is randomly thrown. Participants were presented with 71 trials consisting of all combinations of binary dimensions of shape (e.g., circles and squares) and color (e.g., blue and red) painted onto the (...) sides of each die. In two experiments (N1 = 66, N2 = 65), the conditional event was the dominant interpretation, followed by conjunction, and material conditional responses were negligible. In both experiments, the percentage of participants giving a conditional event response increased from around 40% at the beginning of the task to nearly 80% at the end, with most participants shifting from a conjunction interpretation. The shift was moderated by the order of shape and color in each conditional’s antecedent and consequent: participants were more likely to shift if the antecedent referred to a color. In Experiment 2 we collected response times: conditional event interpretations took longer to process than conjunction interpretations (mean difference 500 ms). We discuss implications of our results for mental models theory and probabilistic theories of reasoning. (shrink)

ABSTRACT Closed time is possible in several senses of ‘possible’. One might like to know, therefore, whether closed time is possible in the sense that it is compatible with standard metaphysical theories of time. In this paper I am concerned with whether closed time is compatible with A and/or B theories of time. A common enough view amongst philosophers is that B theories do but A theories do not allow closed (...) class='Hi'>time. However, I show that prima-facie neither approach allows closed time, but that with a little work standard versions of both approaches do. This shows that there’s no special problem with the notion of eternal return. (shrink)

A highly ordered universe is described in terms of neutrino and electrino alone as basic particles, and length and time alone as dimensional units. New theories are obtained of particles, nuclides, atomic spectra, general relativity, and gravitation.

This useful anthology comprises seventy-nine selections arranged under three headings. Part I is titled "Ancient and Classical Ideas of Space"; part II, "The Classical and Ancient Concepts of Time"; part III, "Modern Views of Space and Time and their Anticipations." According to the general editors of the Boston series, R. S. Cohen and Marx W. Wartofsky, Capek’s choice of contents was governed by the desire to show that "parts of our view of nature greatly and mutually influence other (...) parts, and that our conception of the world keeps evolving. Thus, ideas of time intertwine with ideas of space, and both with ideas of matter and force." F. M. Cornford’s essays, "The Invention of Space" and "The Elimination of Time by Parmenides," introduce parts I and II respectively. In part I, while Descartes, Pascal, Gassendi, Newton, etc., speak for themselves, the ancients and medievals are given other mouthpieces—Duhem’s monumental Le système du monde, for Plato, Aristotle, and the medievals; C. Bailey, for Leucippus, Epicurus and Lucretius; Koyré, Höffding, Jammer, for the period from Bradwardine to William Gilbert. On the subject of time, however, both ancient and classical authors are allowed to express their opinions in their own words, with the understandable exception of the Stoics. Part III begins with the prerelativistic critique of Newton as well as the well-known Clarke-Leibniz discussion on the nature of space and time. This third part, however, is dominated largely by the implications of Einstein’s general and special relativity theories. For instance, we have Minkowski’s "Union of Space and Time." Four items, at least, are devoted to the twin-paradox. Some argue for a static, subjective, or even idealistic conception of space-time whereas positivists like Frank attack Sir James Jeans’ and other idealistic interpretations of relativity as instances of meaningless metaphysics. Part III concludes with Weyl’s objectivistic interpretation of quantum-mechanical indeterminacy. While it is difficult to find an anthology that will please all readers or teachers, this work goes far towards dealing comprehensively with the subject of space and time. As Cohen and Wartofsky note, what is distinctive of Capek’s approach within the field of philosophy of nature and its history is that "he is greatly appreciative of Bergson, James, Peirce and Whitehead" and though influenced by them, he is also critical because of the "understanding of the philosophical import that contemporary physics brings into our picture of the world." In a lengthy introduction, the editor explains his rationale for each item he includes. In general this is very helpful, but in some instances the suggested historical connections are misleading at best, if not simply false or questionable. Einstein for instance is said to have "rejected any absolute frame of reference which would be a substrate of absolutely simultaneous events... within the context of Michelson’s vain search for the absolute motion of the earth." This seems to imply—as many others have claimed—that the negative results of the ether-drift experiment influenced Einstein in formulating his relativity theory, whereas historians have pointed out that if Einstein referred to the experiment, it would have to be as a confirmation of his theory, since he did not learn of the results obtained by Michelson and Morley until after the publication of his revolutionary paper in 1905. Though there are other generalizations in the introduction which might be open to dispute, Capek’s prefatory remarks are in general helpful, and the essay collection as a whole stands on its own feet. It is valuable, if for no other reason, that a number of the selections appear in English translation for the first time.—A.B.W. (shrink)

In this paper I describe a specific emotional reaction to the fact that we will cease to exist, namely existential dread, and I argue that the B-theory of time, according to which reality contains a four-dimensional spacetime manifold and the present time is metaphysically on a par with past and future times, cannot accommodate it. Some may see this as an advantage of the B-theory; some may see it as a problem for the view. My aim is not (...) to argue either for or against the B-theory, but merely to show that it is incompatible with a certain common emotion. The paper is split into three sections. I begin by introducing existential dread. Next, I show how existential dread fits into a widely accepted theory of emotion according to which emotions are intentional states susceptible of being both intelligible and correct, where an emotion is intelligible if, roughly, it makes sense; and is correct if, roughly, it fits its object. The core of the paper is the third section: in that section, I introduce the B-theory of time and I argue that it is incompatible with existential dread. (shrink)

What is the place of Psychoanalytic Theory on our map of knowledge and belief? Various alternatives are considered. Is it a scientific theory? — a myth? — or like a prescientific example of natural philosophy? — a branch of medical knowledge? — a premature empirical synthesis that is an approximation to the truth? Each of these answers runs into objections and difficulties, some of which are examined or noted. On the assumption that it is a provisional story which approximates to (...) the truth, the question is then raised: what can we do to find out how much of an approximation to the truth the theory really is? The relevance and value of psychological studies are discussed; and the suggestion is made that the status of Psychoanalytic Theory will remain an ambiguous one for some time to come. (shrink)

This paper discusses Robin Le Poidevin’s proposal that a commitment to the B-theory of time provides a reason to relinquish the fear of death. After outlining Le Poidevin’s views on time and death, I analyze the specific passages in which he makes his proposal, giving close attention to the claim that, for the B-theorist, one’s life is “eternally real.” I distinguish two possible interpretations of this claim, which I call alethic eternalism and ontic eternalism respectively, and argue, with (...) reference to statements by other B-theroists, that alethic eternalism is the only viable option. I highlight two problems for Le Poidevin’s proposal: firstly, even if alethic eternalism does provide a reason not to fear death, this same reason is available to A-theorists; and secondly, alethic eternalism does not in fact provide such a reason. Having critically assessed possible responses to these problems, I conclude that Le Poidevin’s proposal is unfounded. (shrink)

This contribution seeks to understand the pervasive phenomenon of work compulsion among knowledge workers in our present network society. Knowledge workers not only have to work all the time from anywhere, but they also appear to want to. This study argues that this curious phenomenon may be attributed to the thumotic satisfaction that knowledge work generates. What is more, the neoliberal theory of human capital has found a way to harness thumotic satisfaction to the profit incentive, and has created (...) arguably the most productive working subject to date. The argument is divided into four parts: First, the paper analyses the government(- ality) of control operative in the network society by defining “neoliberalism”. It then focuses on Foucault’s examinations of German and American neoliberalism in the 20th century, treating them as instances of governmentality. The aim is to assess whether employing a governmentality lens is a valid approach for critically analysing present-day neoliberalism. If it proves justifiable, which I argue it does, the study explores the potential valuable insights gained from examining contemporary neoliberalism through this particular analytical framework. Second, the study turns to the “spiritedness” of knowledge workers under the conditions of stealth control that typify the neoliberal network society. Curiously, these highly engaged workers have reportedly experienced increased overall well-being. However, their overinvestment in work appears to be disproportionate to absolute necessity, increased earnings or improved overall quality of life. This paper contends that work compulsion generates and is in turn fuelled by thumotic satisfaction. Third, the study tries to ascertain the connection between neoliberal governmentality and thumos. Neoliberal governmentality appears to have found a way to appropriate thumotic satisfaction to produce and sustain the competitive entrepreneurial spirit. The fourth part of the study considers how the knowledge worker might resist the compulsion to work incessantly. (shrink)

Solmsen presents an interesting discussion of Aristotle's physical theory. He considers each topic, such as genesis, time, the infinite, in terms of Aristotle's similarities and differences with Pre-Socratic and Platonic thought. His results are piece-meal because "Aristotle himself does not investigate each topic of his physical system with his mind focused on a final synthesis of all major conclusions."--J. A. B.

Malcolm's discussion of memory is the most detailed and comprehensive in recent philosophical literature, but it does not result in a philosophical theory of memory or even an "analysis of the concept" of memory. Denying that the word "memory" has a "unified employment," Malcolm spends most of his time exposing mistakes and confusions in what philosophers and psychologists have said about memory. He begins by attacking the common assumption that memory is focused exclusively on the past. Although we may (...) remember what we have seen or done, we may also remember a face or town that we are now seeing, and we may even remember that we have an appointment today or an exam tomorrow. The connection these "objects" of memory have with the past is that, if we do remember them, we must have known them, been acquainted with them, or, as in the case of remembering how to make soup, been able to do them in the past. (shrink)

Collaboration requires agents to coordinate their behavior on the fly, sometimes cooperating to solve a single task together and other times dividing it up into sub‐tasks to work on in parallel. Underlying the human ability to collaborate is theory‐of‐mind (ToM), the ability to infer the hidden mental states that drive others to act. Here, we develop Bayesian Delegation, a decentralized multi‐agent learning mechanism with these abilities. Bayesian Delegation enables agents to rapidly infer the hidden intentions of others by inverse planning. (...) We test Bayesian Delegation in a suite of multi‐agent Markov decision processes inspired by cooking problems. On these tasks, agents with Bayesian Delegation coordinate both their high‐level plans (e.g., what sub‐task they should work on) and their low‐level actions (e.g., avoiding getting in each other's way). When matched with partners that act using the same algorithm, Bayesian Delegation outperforms alternatives. Bayesian Delegation is also a capable ad hoc collaborator and successfully coordinates with other agent types even in the absence of prior experience. Finally, in a behavioral experiment, we show that Bayesian Delegation makes inferences similar to human observers about the intent of others. Together, these results argue for the centrality of ToM for successful decentralized multi‐agent collaboration. (shrink)

In the paper we explore the idea of describing Pawlak’s rough sets using three-valued logic, whereby the value t corresponds to the positive region of a set, the value f — to the negative region, and the undefined value u — to the border of the set. Due to the properties of the above regions in rough set theory, the semantics of the logic is described using a non-deterministic matrix (Nmatrix). With the strong semantics, where only the value t is (...) treated as designated, the above logic is a “common denominator” for Kleene and Łukasiewicz 3-valued logics, which represent its two different “determinizations”. In turn, the weak semantics—where both t and u are treated as designated—represents such a “common denominator” for two major 3-valued paraconsistent logics. We give sound and complete, cut-free sequent calculi for both versions of the logic generated by the rough set Nmatrix. Then we derive from these calculi sequent calculi with the same properties for the various “determinizations” of those two versions of the logic (including Łukasiewicz 3-valued logic). Finally, we show how to embed the four above-mentioned determinizations in extensions of the basic rough set logics obtained by adding to those logics a special two-valued “definedness” or “crispness” operator. (shrink)

It is customary in current philosophy of time to distinguish between an A- (or tensed) and a B- (or tenseless) theory of time. It is also customary to distinguish between an old B-theory of time, and a new B-theory of time. We may say that the former holds both semantic atensionalism and ontological atensionalism, whereas the latter gives up semantic atensionalism and retains ontological atensionalism. It is typically assumed that the B-theorists have been induced by advances (...) in the philosophy of language and related A-theorists’ criticisms to acknowledge that semantic atensionalism can hardly stand, but have also maintained that what is essential for the B-theory is ontological atensionalism, which can be independently defended. Here it is argued that the B-theorists have been too quick in abandoning semantic atensionalism: they can still cling to it. (shrink)

The author states that his purpose in this work is not primarily Peirce scholarship but epistemology. But the concentration is on Peirce’s theory of knowledge, a concentration which centers around what the author thinks is Peirce’s most valuable contribution to the subject—a solution to the problem of skepticism. In contrast to Descartes’ assertion that knowledge must be based on primitive intuitions, Peirce contends that all thought is in process, an organically intertwined system of inferences, a continuous flow of signs. Because (...) thinking is a process in time, it is always fallible. Rather than this being a hindrance to knowledge, Davis sees this as the key to Peirce’s escape from skepticism, for the knowledge so described is a continuous self-corrective process, a web which, if we but make the effort to untangle it, will continue to reward us with advance toward the truth. Of more revolutionary importance to the theory of knowledge, according to Davis, is Peirce’s theory of abduction, his answer to the problem of how synthetic knowledge is possible. Abduction is the act of making up explanatory hypotheses. It issues in insights which are the outgrowth of creativity and imagination. The test of these unifying ideas is their appropriateness or ability to satisfy our sensibilities. It is instinct, or that to which we are naturally bent, which guides the abductive process. Throughout this book great emphasis is placed on the importance of this to Peirce and to an adequate epistemology of instinct, feelings, the work of the heart, or sensibility. The scientist, as Davis sees it, is thus akin in method to the creative artist. While Davis intends also to show how this aspect of Peirce is consistent with his pragmatic maxim, their relationship is never quite clarified in this work. Nevertheless, the book is a well-written and very readable treatment of Peirce’s epistemology. It also includes a great many comparisons with similar and contrasting positions as found in a wide range of contemporary and classical philosophical treatises.—B.A.M. (shrink)

A tension between perspectives that emphasize deterministic versus stochastic processes has sparked controversy in ecology since pre-Darwinian times. The most recent manifestation of the contrasting perspectives arose with Hubbell’s proposed “neutral theory”, which hypothesizes a paramount role for stochasticity in ecological community composition. Here we shall refer to the deterministic and the stochastic perspectives as the niche-based and neutral-based research programs, respectively. Our goal is to represent these perspectives in the context of Lakatos’ notion of a scientific research program. We (...) argue that the niche-based program exhibits all the characteristics of a robust, progressive research program, including the ability to deal with disconfirming data by generating new testable predictions within the program. In contrast, the neutral-based program succeeds as a mathematical tool to capture, as epiphenomena, broad-scale patterns of ecological communities but appears to handle disconfirming data by incorporating hypotheses and assumptions from outside the program, specifically, from the niche-based program. We conclude that the neutral research program fits the Lakatosian characterization of a degenerate research program. (shrink)

Bridging the gap between the world of science and the realm of the spiritual, B. Alan Wallace introduces a natural theory of human consciousness that has its roots in contemporary physics and Buddhism. Wallace's "special theory of ontological relativity" suggests that mental phenomena are _conditioned_ by the brain, but do not _emerge_ from it. Rather, the entire natural world of mind and matter, subjects and objects, arises from a unitary dimension of reality that is more fundamental than these dualities, as (...) proposed by Wolfgang Pauli and Carl Jung. To test his hypothesis, Wallace employs the Buddhist meditative practice of _samatha_, refining one's attention and metacognition, to create a kind of telescope to examine the space of the mind. Drawing on the work of the physicist John Wheeler, he then proposes a more general theory in which the participatory nature of reality is envisioned as a self-excited circuit. In comparing these ideas to the Buddhist theory known as the Middle Way philosophy, Wallace explores further aspects of his "general theory of ontological relativity," which can be investigated by means of _vipasyana_, or insight, meditation. Wallace then focuses on the theme of symmetry in reference to quantum cosmology and the "problem of frozen time," relating these issues to the theory and practices of the Great Perfection school of Tibetan Buddhism. He concludes with a discussion of the general theme of complementarity as it relates to science and religion. The theories of relativity and quantum mechanics were major achievements in the physical sciences, and the theory of evolution has had an equally deep impact on the life sciences. However, rigorous scientific methods do not yet exist to observe mental phenomena, and naturalism has its limits for shedding light on the workings of the mind. A pioneer of modern consciousness research, Wallace offers a practical and revolutionary method for exploring the mind that combines the keenest insights of contemporary physicists and philosophers with the time-honored meditative traditions of Buddhism. (shrink)

The paper has two parts: First, I describe a relatively popular thesis in the philosophy of propositional attitudes, worthy of the name ‘taking tense seriously’; and I distinguish it from a family of views in the metaphysics of time, namely, the A-theories (or what are sometimes called ‘tensed theories of time’). Once the distinction is in focus, a skeptical worry arises. Some A-theorists maintain that the difference between past, present, and future, is to be drawn in (...) terms of what exists: growing-block theorists eschew ontological commitment to future entities; presentists, to future and past entities. Others think of themselves as A-theorists but exclude no past or future things from their ontology. The metaphysical skeptic suspects that their attempt to articulate an ‘eternalist’ version of the A-theory collapses into merely ‘taking tense seriously’– a thesis that does not imply the A-theory. The second half of the paper is the search for a stable eternalist A-theory. It includes discussion of temporary intrinsics, temporal parts, and truth. (shrink)

Ever since Newton created dynamics, there has been controversy about its foundations. Are space and time absolute? Do they form a rigid but invisible framework and container of the universe? Or are space, time, and motion relative? If so, does Newton's 'framework' arise through the influence of the universe at large, as Ernst Mach suggested? Einstein's aim when creating his general theory of relativity was to demonstrate this and thereby implement 'Mach's Principle'. However, it is widely believed that (...) he achieved only partial success. This question of whether motion is absolute or relative has been a central issues in philosophy; the nature of time has perennial interest. Current attempts to create a quantum description of the whole universe keep these issues at the cutting edge of modern research. Written by the world's leading expert on Mach's Principle, The Discovery of Dynamics is a highly original account of the development of notions about space, time, and motion. Widely praised in its hardback version, it is one of the fullest and most readable accounts of the astronomical studies that culminated in Kepler's laws of planetary motion and of the creation of dynamics by Galileo, Descartes, Huygens, and Newton. Originally published as Absolute or Relative Motion?, Vol. 1: The Discovery of Dynamics, The Discovery of Dynamics provides the technical background to Barbour's recently published The End of Time, in which he argues that time disappears from the description of the quantum universe. (shrink)

According to probabilistic theories of reasoning in psychology, people's degree of belief in an indicative conditional `if A, then B' is given by the conditional probability, P(B|A). The role of language pragmatics is relatively unexplored in the new probabilistic paradigm. We investigated how consequent relevance a ects participants' degrees of belief in conditionals about a randomly chosen card. The set of events referred to by the consequent was either a strict superset or a strict subset of the set of (...) events referred to by the antecedent. We manipulated whether the superset was expressed using a disjunction or a hypernym. We also manipulated the source of the dependency, whether in long-term memory or in the stimulus. For subset-consequent conditionals, patterns of responses were mostly conditional probability followed by conjunction. For superset-consequent conditionals, conditional probability responses were most common for hypernym dependencies and least common for disjunction dependencies, which were replaced with responses indicating inferred consequent irrelevance. Conditional probability responses were also more common for knowledge-based than stimulus-based dependencies. We suggest. (shrink)

This paper proposes a view of time that takes passage to be the most basic temporal notion, instead of the usual A-theoretic and B-theoretic notions, and explores how we should think of a world that exhibits such a genuine temporal passage. It will be argued that an objective passage of time can only be made sense of from an atemporal point of view and only when it is able to constitute a genuine change of objects across time. (...) This requires that passage can flip one fact into a contrary fact, even though neither side of the temporal passage is privileged over the other. We can make sense of this if the world is inherently perspectival. Such an inherently perspectival world is characterized by fragmentalism, a view that has been introduced by Fine in his ‘Tense and Reality’ (2005). Unlike Fine's tense-theoretic fragmentalism though, the proposed view will be a fragmentalist view based in a primitive notion of passage. (shrink)

One of the few serious attempts undertaken during the last decade to develop a logic of questions. Belnap's theory comprises three parts so far: a) an informal syntactical treatment of the question-answer relationship, aimed at determining the policies involved in setting up a formalization of questions and answers; b) such a formalization itself ; and c) a semantical analysis leading to explicit definitions of adjectives like "rhetorical," "interesting," "foolish" as applied to questions; "direct," "complete," "corrective," and again "foolish" as applied (...) to answers. This study is a remarkable contribution to a new and rather intricate field of logical inquiry.—A. Z. B. (shrink)

Bridging the gap between the world of science and the realm of the spiritual, B. Alan Wallace introduces a natural theory of human consciousness that has its roots in contemporary physics and Buddhism. Wallace's "special theory of ontological relativity" suggests that mental phenomena are _conditioned_ by the brain, but do not _emerge_ from it. Rather, the entire natural world of mind and matter, subjects and objects, arises from a unitary dimension of reality that is more fundamental than these dualities, as (...) proposed by Wolfgang Pauli and Carl Jung. To test his hypothesis, Wallace employs the Buddhist meditative practice of _samatha_, refining one's attention and metacognition, to create a kind of telescope to examine the space of the mind. Drawing on the work of the physicist John Wheeler, he then proposes a more general theory in which the participatory nature of reality is envisioned as a self-excited circuit. In comparing these ideas to the Buddhist theory known as the Middle Way philosophy, Wallace explores further aspects of his "general theory of ontological relativity," which can be investigated by means of _vipasyana_, or insight, meditation. Wallace then focuses on the theme of symmetry in reference to quantum cosmology and the "problem of frozen time," relating these issues to the theory and practices of the Great Perfection school of Tibetan Buddhism. He concludes with a discussion of the general theme of complementarity as it relates to science and religion. The theories of relativity and quantum mechanics were major achievements in the physical sciences, and the theory of evolution has had an equally deep impact on the life sciences. However, rigorous scientific methods do not yet exist to observe mental phenomena, and naturalism has its limits for shedding light on the workings of the mind. A pioneer of modern consciousness research, Wallace offers a practical and revolutionary method for exploring the mind that combines the keenest insights of contemporary physicists and philosophers with the time-honored meditative traditions of Buddhism. (shrink)

Objective Adolescents have had very limited access to research on biomedical prevention interventions despite high rates of HIV acquisition. One concern is that adolescents are a vulnerable population, and trials carry a possibility of harm, requiring investigators to take additional precautions. Of particular concern is preventive misconception, or the overestimation of personal protection that is afforded by enrolment in a prevention intervention trial. Methods As part of a larger study of preventive misconception in adolescent HIV vaccine trials, we interviewed 33 (...) male and female 16–19-year-olds who have sex with men. Participants underwent a simulated HIV vaccine trial consent process, and then completed a semistructured interview about their understanding and opinions related to enrolment in a HIV vaccine trial. A grounded theory analysis looked for shared concepts, and focused on the content and process of adolescent participants’ understanding of HIV vaccination and the components of preventive misconception, including experiment, placebo and randomisation. Results Across interviews, adolescents demonstrated active processing of information, in which they questioned the interviewer, verbally worked out their answers based upon information provided, and corrected themselves. We observed a wide variety of understanding of research concepts. While most understood experiment and placebo, fewer understood randomisation. All understood the need for safer sex even if they did not understand the more basic concepts. Conclusions Education about basic concepts related to clinical trials, time to absorb materials and assessment of understanding may be necessary in future biomedical prevention trials. (shrink)

Copyright © 2015 by the Society of Criti. Objective: Global lung stress varies considerably with low tidal volume ventilation for acute respiratory distress syndrome. High stress despite low tidal volumes may worsen lung injury and increase risk of death. No widely available parameter exists to assess global lung stress. We aimed to determine whether the volume delivered during a recruitment maneuver is inversely associated with lung stress and mortality in acute respiratory distress syndrome. Design: Substudy of an acute respiratory distress (...) syndrome clinical trial on esophageal pressure-guided positive end-expiratory pressure titration. Setting: U.S. academic medical center. Patients: Forty-two patients with acute respiratory distress syndrome in whom airflow, airway pressure, and esophageal pressure were recorded during the recruitment maneuver. Interventions: A single recruitment maneuver was performed before initiating protocol-directed ventilator management. Recruitment maneuvers consisted of a 30-second breath hold at 40 cm H2O airway pressure under heavy sedation or paralysis. VRM was calculated by integrating the flow-time waveform during the maneuver. End-inspiratory stress was defined as the transpulmonary pressure during end-inspiratory pause of a tidal breath and tidal stress as the transpulmonary pressure difference between end-inspiratory and end-expiratory pauses. Measurements and Main Results: VRM ranged between 7.4 and 34.7 mL/kg predicted body weight. Lower VRM predicted high end-inspiratory and tidal lung stress. After adjusting for Pao2/Fio2 and either driving pressure, tidal volume, or plateau pressure and positive end-expiratory pressure, VRM remained independently associated with both end-inspiratory and tidal stress. In unadjusted analysis, low VRM predicted increased risk of death. VRM remained significantly associated with mortality after adjusting for study arm. Conclusions: Low VRM independently predicts high lung stress and may predict risk of death in patients with acute respiratory distress syndrome. (shrink)

Theories of beauty are often divided into the objective and the subjective. I am doubtful whether a rigid distinction between the two can be maintained. It is difficult for an objective theory to assert that the impression of beauty is received quite passively, without any reaction or co-operation on the part of the subject, which is likely to be similar in the various cases.

Solmsen presents an interesting discussion of Aristotle's physical theory. He considers each topic, such as genesis, time, the infinite, in terms of Aristotle's similarities and differences with Pre-Socratic and Platonic thought. His results are piece-meal because "Aristotle himself does not investigate each topic of his physical system with his mind focused on a final synthesis of all major conclusions."--J. A. B.

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Business and Society: Ethics and Stakeholder Management, 5th edition employs a stakeholder management framework, emphasizing business' social and ethical responsibilities to both external and internal stakeholder groups. A twin theme of business ethics to illustrate how ethical or moral considerations are included the public issues facing organizations and the decision making process of managers. The text is written from a managerial perspective that along with the twin themes of stakeholders and ethics, shows how to identify stakeholders, incorporate their concerns into (...) the organization's strategy and operations, and also integrate ethical wisdom into their decision making process. In addition, 35 case histories are included to help connect theory and practice through timely and interesting examples. (shrink)

The purpose of this paper is to explore the connection between change and the B-theory of time, sometimes also called the Scientific view of time, according to which reality is a four-dimensional spacetime manifold, where past, present and future things equally exist, and the present time and non-present times are metaphysically the same. I argue in favour of a novel response to the much-vexed question of whether there is change on the B-theory or not. In fact, B-theorists (...) are often said to hold a ‘static’ view of time. But this far from being innocent label: if the B-theory of time presents a model of temporal reality that is static, then there is no change on the B-theory. From this, one can reasonably think as follows: of course, there is change, so the B-theory must be false. What I plan to do in this paper is to argue that in some sense there is change on the B-theory, but in some other sense, there is no change on the B-theory. To do so, I present three instances of change: Existential Change, namely the view that things change with respect to their existence over time; Qualitative Change, the view that things change with respect to how they are over time; Propositional Change, namely the view that things (i.e. propositions) change with respect to truth value over time. I argue that while there is a reading of these three instances of change that is true on the B-theory, and so there is change on the B-theory in this sense, there is a B-theoretical reading of each of them that is not true on the B-theory, and therefore there is no change on the B-theory in this other sense. (shrink)

The primary purpose of this book "is to analyze and clarify certain fundamental concepts, principles, and procedures in both classical and relativistic mechanics." At the same time, it attempts to provide a grounding in the theory for the philosopher of science who must deal with the sometimes technical literature on the philosophical implications of relativistic mechanics. "This book, then, is an attempt at fundamental philosophic clarification embedded in the format of an introductory work." Its first six chapters deal with (...) the methodological foundations of classical mechanics and electrodynamics, as conceived prior to Einstein. Thus, the next six chapters introduce special relativity in such a way that it is connected with the tradition from which it arose. Although the book is not primarily a historical treatment of the theory, this added perspective is welcome because almost invariably philosophers of relativity portray the theory as if it arose without the intermediary of electrodynamics. (shrink)

Translational research in medicine requires researchers to identify the steps to transfer basic scientific discoveries from laboratory benches to bedside decision-making, and eventually into clinical practice. On a parallel track, philosophical work in ethics has not been obliged to identify the steps to translate theoretical conclusions into adequate practice. The medical ethicist A. Cribb suggested some years ago that it is now time to debate ‘the business of translational’ in medical ethics. Despite the very interesting and useful perspective on (...) the field of medical ethics launched by Cribb, the debate is still missing. In this paper, I take up Cribb’s invitation and discuss further analytic distinctions needed to base an ethics aiming to translate between theory and practice. (shrink)

The author briskly gives the principles of criticism which he will follow in examining Kant's theory of time, and the distinctions between absolute time, psychological time, and the duration of events and processes which must be made in order to deal with the time theories of Kant and his great predecessors Newton and Leibniz and their defenders. Al-Azm then follows Kant's writings from 1747 through his brief conversion to the Newtonian "receptacle" theory, through the critical (...) period. He considers the Dissertation of 1770, at least in so far as it deals with space and time, to belong to the latter. The principles of criticism are especially relevant to Al-Azm's interpretation of Kant's time doctrine in the critical period. He holds that we must carefully bear in mind Kant's alternation of analytic and synthetic methods, and their dialectic interplay. If we do so, we can explain away the "patchwork" theory of Kemp Smith and others, as the obscurities and apparent inconsistencies and paradoxes which are resolvable in the light of the roles played for Kant by the approaches he employs. Within the first Critique, the teachings on time in the Aesthetic and the Analytic constitute a "genuine dialectic of a highly complex order." Thus, Kant's final position should be sought in the progressive modifications of the preliminary position. Al-Azm regards the Aesthetic as offering merely provisional statements on the subject of time, reached by a process of analysis, at an early dialectical stage, and offering a starting point for a fresh stage in analysis which aims "at the unveiling of the synthetic processes of the understanding." This is accomplished in the Analytic. In a last section, on the first Antinomy, the author considers Strawson's essay, The Bounds of Sense, published in 1966, and cites passages which he feels defend Kant's theory of time, seen in its relation to the critical philosophy, as successfully against Strawson's interpretation as against the claims of its Leibnizian and Newtonian rivals.--M. B. M. (shrink)

In recent years, the genetic testing and selection of IVF embryos, known as preimplantation genetic testing (PGT), has gained much traction in clinical assisted reproduction for preventing transmission of genetic defects. However, a more recent ethically and morally controversial development in PGT is its possible use in selecting IVF embryos for optimal intelligence quotient (IQ) and other non–disease-related socially desirable traits, such as tallness, fair complexion, athletic ability, and eye and hair colour, based on polygenic risk scores (PRS), in what (...) is referred to as PGT-P. Artificial intelligence (AI) and machine learning–based analysis of big data sets collated from genome sequencing of specific human ethnic populations can be used to estimate an individual embryo’s likelihood of developing such multifactorial traits by analysing the combination of specific genetic variants within its genome. Superficially, this technique appears compliant with Islamic principles and ethics. Because there is no modification of the human genome, there is no tampering with Allah’s creation (_taghyīr khalq Allah_). Nevertheless, a more critical analysis based on the five maxims of Islamic jurisprudence (_qawa'id fiqhiyyah_) that are often utilized in discourses on Islamic bioethics, namely _qaṣd_ (intention), _yaqın̄_ (certainty), _ḍarar_ (injury), _ḍarūra_ (necessity), and _`urf_ (custom), would instead reveal some major ethical and moral flaws of this new medical technology in the selection of non–disease-related socially desirable traits, and its non-compliance with the spirit and essence of Islamic law (shariah). Muslim scholars, jurists, doctors, and biomedical scientists should debate this further and issue a fatwa on this new medical technology platform. (shrink)

J. Solomon [Journal de Physique 4, 34 (1933)] produced an argument of great generality claiming to demonstrate the impossibility of hidden variables in quantum theory, an argument which M. Jammer [The Philosophy of Quantum Mechanics(Wiley, New York, 1974)] said raised a number of questions. For the first time, this argument is discussed, a simple hidden variable model violating the argument is analysed in detail, and the error in the proof is located.

During a pandemic, where there is widespread human infection, various and varying measures are taken that are targeted at public health objectives. During the early stages of a pandemic, these objectives may focus on containing the disease and minimizing its spread, but they may switch to mitigation as the emergent infectious disease takes hold in a population. There has been considerable debate and elucidation of the ethical principles and framework for the various responses including the need to fast track research (...) and vaccine development. However, the measures imposed during a pandemic would have unintended and untoward effect on ongoing clinical research. For example, precautionary measures, such as social distancing, may hamper ongoing clinical research, because recruitment and participation of patients and healthy volunteers is a potential source of virus spread. In this paper, we argue that a framework is needed to ensure the continuity of such research. Such a framework that considers the pertinent issues would need the ‘buy in’ of the key stakeholders (policy makers, funding agencies, institutional authorities, researchers and subjects) to ensure that the issues that are ethically relevant to pandemic planning would not be neglected or overlooked. (shrink)

This article is a response to Clifford Williams’s claim that the debate between A- and B theories of time is misconceived because these theories do not differ. I provide some missing support for Williams’s claim that the B-theory includes transition, by arguing that representative B-theoretic explanations for why we experience time as passing (even though it does not) are inherently unstable. I then argue that, contra Williams, it does not follow that there is nothing at stake (...) in the A- versus B debate. (shrink)

The study of graph structure has advanced in recent years with great strides: finite graphs can be described algebraically, enabling them to be constructed out of more basic elements. Separately the properties of graphs can be studied in a logical language called monadic second-order logic. In this book, these two features of graph structure are brought together for the first time in a presentation that unifies and synthesizes research over the last 25 years. The author not only provides a (...) thorough description of the theory, but also details its applications, on the one hand to the construction of graph algorithms, and, on the other to the extension of formal language theory to finite graphs. Consequently the book will be of interest to graduate students and researchers in graph theory, finite model theory, formal language theory, and complexity theory. (shrink)

This book is a synthesis of more than three decades of research into the concept of time and its semiotic nature. If traditional philosophy – and philosophy of time should be no exception – in the shadow of advancing biology can be said to have reached an impasse, one important reason for this, in harmony with Wittgenstein’s vision, appears to have been its lack of appropriate tools for explicating language. The present theory of time proceeds, accordingly, from (...) the exploration of temporal expressions in language as an evolutionary fact. It derives in a hypothetical, coherent feedback process of hierarchically ordered distinctions the semantics of time from its biologically dictated perceptual and cognitive-pragmatic origins. The corresponding abductive-regulative model is anchored in the assumption of biological rhythmization as the very foundation of perception and mental/physical action. Understood to originate in space and spatial perspective, time reveals itself as an instrument for temporal perspective on motion (events and situations) in a process of analysis, i.e., discontinuation of chaos made divisible and continuous by the rhythmical screen. Whereas traditional philosophy of time paid attention almost exclusively to the temporal category of tense, the biopragmatic model sees strong evidence in the perspectival nature of time for ascribing the decisive, and probably universal, role in temporal analysis to the linguistic category of aspect. Aspect may, according to the present findings, be assumed to partake already of change-of-state and cause-effect analysis without which man’s adaptation to new situations – and precondition for survival – would be inconceivable. The proposed model of space/time cognition, inspired by Hegelian dialectics, Heidegger-Gadamer’s hermeneutic circle and Peircean logic, makes Kantian a priori superfluous and liberates time from its enigmatic appearance. For the first time in temporal studies it thus appears possible to derive hypothetically linguistic expressions of time all the way from pretemporal, homogeneous continuity effected by biological rhythmization, via pretemporal metonymic (Gestalt), chunk-wise partitioning – as a general precondition for the perception and, based on primary metaphorization, the cognition of things, space and motion – to temporal analysis/discontinuation proper, primarily by aspectual perspective, and the subsequent synthesized, heterogeneous continuity of temporally ordered events. The conception of time, so disastrous for modern temporal logic, i.e., as moving object assigned extension, divisible continuity (‛linearity’) and direction, can be shown to have emerged as a result of secondary metaphorization. (shrink)

In this paper I consider two strategies for providing tenseless truth-conditions for tensed sentences: the token-reflexive theory and the date theory. Both theories have faced a number of objections by prominent A-theorists such as Quentin Smith and William Lane Craig. Traditionally, these two theories have been viewed as rival methods for providing truth-conditions for tensed sentences. I argue that the debate over whether the token-reflexive theory or the date theory is true has arisen from a failure to distinguish (...) between conditions for the truth of tensed tokens and conditions for the truth of propositions expressed by tensed tokens. I demonstrate that there is a true formulation of the token-reflexive theory that provides necessary and sufficient conditions for the truth of tensed tokens, and there is a true formulation of the date theory that provides necessary and sufficient conditions for the truth of propositions expressed by tensed tokens. I argue that once the views are properly formulated, the A-theorist’s objections fail to make their mark. However, I conclude by claiming that even though there is a true formulation of the token-reflexive theory and a true formulation of the date theory, the New B-theory nonetheless fails to provide a complete account of the truth and falsity of tensed sentences. (shrink)

We formulate and analyze the dynamics of an influenza pandemic model with vaccination and treatment using two preventive scenarios: increase and decrease in vaccine uptake. Due to the seasonality of the influenza pandemic, the dynamics is studied in a finite time interval. We focus primarily on controlling the disease with a possible minimal cost and side effects using control theory which is therefore applied via the Pontryagin’s maximum principle, and it is observed that full treatment effort should be given (...) while increasing vaccination at the onset of the outbreak. Next, sensitivity analysis and simulations (using the fourth order Runge-Kutta scheme) are carried out in order to determine the relative importance of different factors responsible for disease transmission and prevalence. The most sensitive parameter of the various reproductive numbers apart from the death rate is the inflow rate, while the proportion of new recruits and the vaccine efficacy are the most sensitive parameters for the endemic equilibrium point. (shrink)

Open theists argue that God's relationship to time, as conceived in classical theism, is erroneous. They explain that it is contradictory for an atemporal being to act in a temporal universe, including experiencing its temporal successions. Contrary to the atemporalists, redemptive history has shown that God interacts with humans in time. This relational nature of God nullifies the classical notion of God as timelessly eternal. Therefore, it lacks a philosophical and theological basis. Because God is in time, (...) He does not know all future contingencies and, therefore, changes. This study examines open theism's appropriation of the A and B theories of time to the divine-human relationship. The study argues that divine temporality does not solve the tension of divine-human relationships, especially in relation to the future. Further, historical divine temporality does not negate the fact of divine atemporality. It mainly stems from God's choice to create temporal creatures and His relationship with them. Furthermore, if it is not logically and metaphysically contradictory for an omnipresent being to act in space, then it follows that an atemporal being can act in time. Whether time is understood from the metric or psychological point of view, it does not transcend God, and therefore, the limitation it places on human creatures with respect to the future does not apply to God. Lastly, although a few philosophers reject the notion of eternity as timelessly eternal, the doctrine has a philosophical and theological basis in the Scripture. (shrink)

Time belongs to a handful of categories (like form, symbol, cause) that are genuinely transdisciplinary. Time touches every dimension of our being, every object of our attention - including attention itself. It therefore can belong to no single field of study. Of course, this universalist view of time is not itself universal but rather is a product of the modern age, an age that conceived of itself as the 'new' time. Time has thus gained new (...) importance as a theme of general research with the 'post-modern turn' now manifest in many areas of intellectual endeavor, especially in the humanities and social sciences. 'Chronotypes' are models or patterns through which time assumes practical or conceptual significance. Time is not given but (as the subtitle indicates) fabricated in an ongoing process. Chronotypes are themselves temporal and plural, constantly being made and remade at multiple individual, social, and cultural levels. They interact, they change over time, and they have histories, whose construal is itself an act of temporal construction. This book - an interdisciplinary collaboration of philosophers, historians, literary critics, and anthropologists - examines the ways individuals, societies, and cultures make sense of time by constructing it in diverse patterns. Its title intentionally echoes a concept of narrative theory, Mikhail Bakhtin's 'chronotype', because narrative recurs as a chief form within which we build temporality. The topics treated by these essays range from story-telling to cross-cultural communication, from epistemological debates to concepts of historical periodization, from the construction of life stories to the stratification of social time. (shrink)

The paper illustrates how organic chemists dramatically altered their practices in the middle part of the twentieth century through the adoption of analytical instrumentation - such as ultraviolet and infrared absorption spectroscopy and nuclear magnetic resonance spectroscopy - through which the difficult process of structure determination for small molecules became routine. Changes in practice were manifested in two ways: in the use of these instruments in the development of 'rule-based' theories; and in an increased focus on synthesis, at the (...) expense of chemical analysis. These rule-based theories took the form of generalizations relating structure to chemical and physical properties, as measured by instrumentation. This 'Instrumental Revolution' in organic chemistry was two-fold: encompassing an embrace of new tools that provided unprecedented access to structures, and a new way of thinking about molecules and their reactivity in terms of shape and structure. These practices suggest the possibility of a change in the ontological status of chemical structures, brought about by the regular use of instruments. The career of Robert Burns Woodward (1917-1979) provides the central historical examples for the paper. Woodward was an organic chemist at Harvard from 1937 until the time of his death. In 1965, he won the Nobel Prize in Chemistry. (shrink)