BackgroundAn increasing number of studies utilize intracranial electrophysiology in human subjects to advance basic neuroscience knowledge. However, the use of neurosurgical patients as human research subjects raises important ethical considerations, particularly regarding informed consent and undue influence, as well as subjects’ motivations for participation. Yet a thorough empirical examination of these issues in a participant population has been lacking. The present study therefore aimed to empirically investigate ethical concerns regarding informed consent and voluntariness in Parkinson’s disease patients undergoing deep brain (...) stimulator (DBS) placement who participated in an intraoperative neuroscience study.MethodsTwo semi-structured 30-minute interviews were conducted preoperatively and postoperatively via telephone. Interviews assessed participants’ motivations for participation in the parent intraoperative study, recall of information presented during the informed consent process, and participants’ postoperative reflections on the research study.ResultsTwenty-two participants (mean age = 60.9) completed preoperative interviews at a mean of 7.8 days following informed consent and a mean of 5.2 days prior to DBS surgery. Twenty participants completed postoperative interviews at a mean of 5 weeks following surgery. All participants cited altruism or advancing medical science as “very important” or “important” in their decision to participate in the study. Only 22.7% (n = 5) correctly recalled one of the two risks of the study. Correct recall of other aspects of the informed consent was poor (36.4% for study purpose; 50.0% for study protocol; 36.4% for study benefits). All correctly understood that the study would not confer a direct therapeutic benefit to them.ConclusionEven though research coordinators were properly trained and the informed consent was administered according to protocol, participants demonstrated poor retention of study information. While intraoperative studies that aim to advance neuroscience knowledge represent a unique opportunity to gain fundamental scientific knowledge, improved standards for the informed consent process can help facilitate their ethical implementation. (shrink)

Study on the educational thoughts of Mother, 1878-1973, associate of Aurobindo Ghose, 1872-1950, Indic philosopher.

Background: Positive effects of acute exercise on cognitive performances in general inspired research that investigated the effects of acute exercise on specific cognitive subdomains. Many existing studies examined beneficial effects of acute exercise on subsequent set shifting performance in healthy adults. Set shifting, a subdomain of executive function, is the ability to switch between different cognitive sets. The results of existing studies are inconsistent. Therefore, a meta-analysis was conducted that pooled available effect sizes. Additionally, moderator analyses were carried out to (...) identify covariates that determine the magnitude of exercise-induced set shifting benefits.Methods: Medline, PsycINFO, and SPORTDiscus were searched for eligible studies. Hedges' g corrected standardized mean difference values were used for analyses. Random-effects weights were applied to pool effects. Potential moderation of the effect of acute exercise on subsequent set shifting performance by exercise intensity, type of exercise, participants' age, and type of control group were examined.Results: Twenty-two studies were included into analysis. All aggregated effect sizes ranged from small to moderate. Overall, a small significant beneficial effect was revealed. Heterogeneity of included effect sizes was moderate and significant. Moderator analyses revealed a larger average effect in older adults than for studies examining younger adults. Light exercise led to larger effects than moderate or vigorous exercise. Studies testing acute exercise against active control groups showed a noticeably smaller average effect than studies that used passive or cognitive engaging control groups. Interestingly, application of resistance or aerobic exercise led to no different average effect sizes. However, none of the tested covariates reached statistical significance.Conclusion: Acute exercise improves subsequent set shifting performance. However, effect sizes are small, making the relevance for everyday life questionable. The results indicate that older adults benefit more from acute exercise than younger adults do. Light intensity exercise seems most effective while the type of exercise does not seem to influence the magnitude of effects. Research designs with active control groups show the smallest average effect, raising concerns about placebo effects.PROSPERO registration number: CRD42019138799. (shrink)

Post-globalization trends have left many people with a sense of insecurity—on both the economic and the employment fronts. Business re-engineering, downsizing, lay-offs, excessive consumerism and greed have altered the rules of the business game. Skewed attention to mere economic criteria in many business organizations, even at the cost of societal and environmental factors, is leading to a sense of hollowness, ‘something missing’, in the organization and its employees. People are making every attempt to discover this ‘missing component’ in their lives, (...) with particular reference to their work lives. This ‘missing component’ is referred to as ‘spirit at work’ in management literature. Bringing in spirit at work has become a matter of priority for many business organizations, in their drives for sustained success. Spirit at work is about care, compassion, integrity, and about attempting to live one’s values at the workplace. It is about employees who are passionate and energized by their work, who find meaning and purpose and pursue excellence in their work, and who feel that they can express their complete selves at work. It is about individuals and organizations that see work as an opportunity to grow and to contribute to society in a meaningful way. Spirit at work can be better understood by gaining clarity about the key aspects that constitute this concept. This article reviews the extant litera-ture on spirit at work, highlights the key dimensions of spirit at work, and elaborates on each of them. A number of Indian scholars like S.K. Chakraborty, Subhash Sharma, M.B. Athreya, Panduranga Bhatta and others have proposed an Indian perspective of spirit at work and have elaborated on it since a decade and a half. This article extends the Indian perspective further, based on Indian psychophilosophy, and establishes its comprehensive and inclusive nature that enables incorporation of most of the key dimensions of spirit at work as identified in literature. (shrink)

This is a welcome reprint of a book that continues to grow in importance.

ABSTRACT:Globally, family firms are the dominant organizational form. Family involvement in business and unique family dynamics impacts organizational strategy and performance. However, family control of business has rarely been adopted as a discriminating variable in the organizations and the natural environment (ONE) research field. Drawing on the theory of planned behavior we develop a conceptual framework of the drivers of proactive environmental strategy (PES) in family firms. We argue that family involvement in business influences the attitudes, subjective norms, and perceived (...) behavioral control of a firm’s dominant coalition. Together these factors determine the extent of the dominant coalition’s intentions to undertake PES. Further, family firms with lower levels of relationship conflict within the controlling family will be more successful in translating the dominant coalition’s intentions to allocate resources for the pursuit of PES. Research implications of the theory are discussed. (shrink)

ABSTRACT:Globally, family firms are the dominant organizational form. Family involvement in business and unique family dynamics impacts organizational strategy and performance. However, family control of business has rarely been adopted as a discriminating variable in the organizations and the natural environment (ONE) research field. Drawing on the theory of planned behavior we develop a conceptual framework of the drivers of proactive environmental strategy (PES) in family firms. We argue that family involvement in business influences the attitudes, subjective norms, and perceived (...) behavioral control of a firm’s dominant coalition. Together these factors determine the extent of the dominant coalition’s intentions to undertake PES. Further, family firms with lower levels of relationship conflict within the controlling family will be more successful in translating the dominant coalition’s intentions to allocate resources for the pursuit of PES. Research implications of the theory are discussed. (shrink)

The author presents and defends three theses: (1) "the first is that it is not profitable for us at present to do moral philosophy; that should be laid aside at any rate until we have an adequate philosophy of psychology." (2) "the second is that the concepts of obligation, And duty... And of what is morally right and wrong, And of the moral sense of 'ought', Ought to be jettisoned if this is psychologically possible...." (3) "the third thesis is that (...) the differences between the well-Known english writers on moral philosophy from sidgwick to the present day are of little importance." (staff). (shrink)

On the spiritual life and mysticism of Shaivite philosophy of Kashmir.

On the doctrines of Madhva, 13th century exponent of the Dvaita school in Hindu philosophy.

Machine generated contents note: Foreword ix -- Preface xi. -- Introduction xiii -- CHAPTER I -- The Concept of God 1 -- CHAPTER I -- The Case for God 15 -- CHAPER m -- The Case Against God 31 -- CHAPTER IV -- God, Suffering and Human Beings 37 -- CHAPTER V -- Revelation, Faith and Knowledge 47 -- CHAPTER VI -- Epistemology and Ontology 63 -- CHAER VII -- Religious Language 77 -- CHAPTER v -- Religious Language and Truth (...) 89 -- CHAPTER IX -- The Problem of Religious Pluralism 109 -- CHAPTER X -- Human Destiny: Western Perspectives 121 -- CHAPTER XI -- Human Destiny: Indic Perspectives 135 -- Recommended Reading .153. (shrink)

In Xenophon’s Socratic literature, there is repeated emphasis on the utility the friends provide one another. One extended passage, _Memorabilia_ 2.6, shows that Socrates takes a good person to care about a friend both for the benefits to be gained for oneself and for the sake of the other’s welfare. Genuine friendship, for Socrates, is not transactional or self-interested but rather rooted in the mutual benefit that only good people can provide one another.

This book offers an introduction to the Sophists of fifth-century Athens and a new overall interpretation of their thought. Since Plato first animadverted on their activities, the Sophists have commonly been presented as little better than intellectual mountebanks - a picture which Professor Kerferd forcefully challenges here. Interpreting the evidence with care, he shows them to have been part of an exciting and historically crucial intellectual movement. At the centre of their teaching was a form of relativism, most famously expressed (...) by Protagoras as 'Man is the measure of all things', and which they developed in a wide range of views - on knowledge and argument, virtue, government, society, and the gods. On all these subjects the Sophists did far more than simply provoke Plato to thought. Their contributions were substantial and serious; they inaugurated the debate on many central philosophical questions and decisively shifted the focus of philosophical attention from the cosmos to man. (shrink)

Comments on: JRE Focus on The 50th Anniversary of the Universal Declaration ofHuman Rights, Journal of Religious Ethics 26.2 “Rethinking Human Rights: A Review Essay on Religion, Relativism, and Other Matters” by David Little, Journal of Religious Ethics 27.1.

The phenomenon of dreamless sleep and its philosophical consequences, particularly deep sleep's relevance to such issues as Self, Consciousness, Personal Identity, Unity of Subject, and Disembodied Life, are explored through a discussion, in varying detail, of certain noted doctrines and views--for example of Advaita Vedānta, Hegel, and H. D. Lewis. Finally, with a cue from Leibniz and McTaggart, the suggestion is made that at no stage during sleep is the self without some perceptions, however indeterminate. Support for this hypothesis is (...) claimed from the current psychoanalytic opinion that mental activity does not cease during any part of sleep and that human beings continue to dream even in the so-called dreamless state. (shrink)