In this paper, the author shows how research ethics committees must deal with illegality in the research protocol. He defines their legal duty by reference to the 2001 Clinical Trials Directive, and especially in the key areas of insurance, indemnity and no-fault compensation. The author is critical of the current GAfREC and recent guidelines issued by the Royal College of Physicians. He concludes that new rules are needed to replace the 2001 edition of GAfREC.

This article is a response to the public consultation on the draft Code of Practice issued by the Human Tissue Authority on the import and export of human bodies, body parts and tissue. The question is whether the Draft Code and the Human Tissue Act go far enough to prevent the unethical acquisition and movement of human tissue. I conclude that the answer to this question is ‘no’ and go on to demonstrate how the identified deficiencies can be remedied.

In this paper the author argues that the Academy of Medical Sciences's ‘Review of the regulation and governance of medical research’ has produced a set of muddled recommendations that could increase complexity and uncertainty in research governance rather than reduce it. Issues discussed in the paper include the additional legal burden placed upon the newly proposed Health Research Agency by the plan for a National Research Governance Service and its system of centralized permissions, the consequences that this may have for (...) the research ethics committees in the discharge of their legal duty, and the unanswered questions surrounding the TGN1412 incident. (shrink)

This article is a response to the letter from the Department of Health that was published in the previous edition of the Research Ethics Review upon the matter of the legal duty of the research ethics committees. It also deals briefly with the article published in the current edition of Research Ethics Review by Colin Parker on what appears to be the same topic.

In this article, the author contends that the current indemnity provided to REC members is unfair and is so badly drafted that it cannot be described as an indemnity at all. He contends that the Appointing Authorities should give guidance to clarify the scope of the indemnity or replace it. The author discusses potential legal claims by REC members against their Appointing Authority if this is not provided. The legal liability of REC members for negligence and other claims is also (...) discussed. The author provides a solution in a simpler form of indemnity framed by reference to actual claims that can be made against a REC member. (shrink)

A work of remarkable cross-disciplinary scholarship, this volume illuminates the origins of the human sciences and offers a new view of the Enlightenment that ...

The human sciences—including psychology, anthropology, and social theory—are widely held to have been born during the eighteenth century. This first full-length, English-language study of the Enlightenment sciences of humans explores the sources, context, and effects of this major intellectual development. The book argues that the most fundamental inspiration for the Enlightenment was the scientific revolution of the seventeenth century. Natural philosophers from Copernicus to Newton had created a magisterial science of nature based on the realization that the physical world operated (...) according to orderly, discoverable laws. Eighteenth-century thinkers sought to cap this achievement with a science of _human_ nature. Belief in the existence of laws governing human will and emotion; social change; and politics, economics, and medicine suffused the writings of such disparate figures as Hume, Kant, and Adam Smith and formed the basis of the new sciences. A work of remarkable cross-disciplinary scholarship, this volume illuminates the origins of the human sciences and offers a new view of the Enlightenment that highlights the period's subtle social theory, awareness of ambiguity, and sympathy for historical and cultural difference. (shrink)

There is thought to be a rich connection between the self and the phenomenology of episodic memory. Despite the emphasis on this link, the precise relation between the two has been underexplored. In fact, even though it is increasingly acknowledged that there are various facets of the self, this notion of the multifaceted self has played very little role in theorizing about the phenomenology of episodic memory. Getting clear about the complex phenomenology of episodic memory involves getting clear about various (...) components that contribute to the sense of self. Inspired by work on 4E cognition, and focusing on the phenomenological feature of felt connections, we show that the phenomenology of episodic memory can be modulated by focusing on different facets — embodied, extended, embedded, and ecological — of the self. (shrink)

A recalled memory is deemed authentic when it accurately represents how one experienced the original event. However, given the convincing research in cognitive science on the constructive nature of memory, this inevitably leads to the question of the ‘bounds of authenticity’. That is, how similar does a memory have to be to the original experience to still count as authentic? In this paper we propose a novel account of ‘Situated Authenticity’ which highlights that the norms of authenticity are context-dependent. In (...) particular, we show that each of the three core functions of episodic memory (self, social and directive) is correlated with patterned changes in levels of conceptualization (e.g., concrete construal versus abstract construal of the event). We support this theoretical account with existing empirical data. We conclude the paper by showing how our account of Situated Authenticity supplements ongoing discussions on memory contextualism, and providing an outline of how our account, which is currently elaborated targeting a phenomenological level, may also be elaborated on a processing level using the concept of representational format. (shrink)

It has become a truism that the ethics of artificial intelligence (AI) is necessary and must help guide technological developments. Numerous ethical guidelines have emerged from academia, industry, government and civil society in recent years. While they provide a basis for discussion on appropriate regulation of AI, it is not always clear how these ethical guidelines were developed, and by whom. Using content analysis, we surveyed a sample of the major documents (_n_ = 47) and analyzed the accessible information regarding (...) their methodology and stakeholder engagement. Surprisingly, only 38% report some form of stakeholder engagement (with 9% involving citizens) and most do not report their methodology for developing normative insights (15%). Our results show that documents with stakeholder engagement develop more comprehensive ethical guidance with greater applicability, and that the private sector is least likely to engage stakeholders. We argue that the current trend for enunciating AI ethical guidance not only poses widely discussed challenges of applicability in practice, but also of transparent development (as it rather behaves as a black box) and of active engagement of diversified, independent and trustworthy stakeholders. While most of these documents consider people and the common good as central to their telos, engagement with the general public is significantly lacking. As AI ethics moves from the initial race for enunciating general principles to more sustainable, inclusive and practical guidance, stakeholder engagement and citizen involvement will need to be embedded into the framing of ethical and societal expectations towards this technology. (shrink)

Intellectual humility, which entails openness to other views and a willingness to listen and engage with them, is crucial for facilitating civil dialogue and progress in debate between opposing sides. In the present research, we tested whether intellectual humility can be reliably detected in discourse and experimentally increased by a prior self-affirmation task. Three-hundred and three participants took part in 116 audio and video-recorded group discussions. Blind to condition, linguists coded participants’ discourse to create an intellectual humility score. As expected, (...) the self-affirmation task increased the coded intellectual humility, as well as participants’ self-rated prosocial affect (e.g., empathy). Unexpectedly, the effect on prosocial affect did not mediate the link between experimental condition and intellectual humility in debate. Self-reported intellectual humility and other personality variables were uncorrelated with expert-coded intellectual humility. Implications of these findings for understanding the social psychological mechanisms underpinning intellectual humility are considered. (shrink)

Research Ethics, Volume 18, Issue 2, Page 126-131, April 2022. Engaging citizens and patients in research has become a truism in many fields of health research. It is now seen as a laudable—if not compulsory—activity in research for yielding more impactful and meaningful citizen/patient outcomes and steering research in the right direction. Although this research approach is increasingly common and commendable, we recently encountered a major obstacle in obtaining an ethics certificate from an institutional review board to conduct a study (...) that places citizen/patient perspectives on equal footing with those of academic/policy experts. The obstacle was the interpretation of fairness in terms of compensation for research participation. In terms of research ethics, this raised an important question: Should all types of participants be compensated equally, or should exceptions be made for citizen/patient participants? We argue that there are good reasons for exceptionalism and that clearer guidance on citizen/patient engagement in research should be embedded into research ethics doctrine. (shrink)

Engaging citizens and patients in research has become a truism in many fields of health research. It is now seen as a laudable—if not compulsory—activity in research for yielding more impactful and meaningful citizen/patient outcomes and steering research in the right direction. Although this research approach is increasingly common and commendable, we recently encountered a major obstacle in obtaining an ethics certificate from an institutional review board to conduct a study that places citizen/patient perspectives on equal footing with those of (...) academic/policy experts. The obstacle was the interpretation of fairness in terms of compensation for research participation. In terms of research ethics, this raised an important question: Should all types of participants be compensated equally, or should exceptions be made for citizen/patient participants? We argue that there are good reasons for exceptionalism and that clearer guidance on citizen/patient engagement in research should be embedded into research ethics doctrine. (shrink)

In light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries—such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna—challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results (...) and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms. Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences. Contributors. Thomas Bürglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Müller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf. (shrink)

Regular musical activity as a complex multimodal lifestyle activity is proposed to be protective against age-related cognitive decline and Alzheimer’s disease. This cross-sectional study investigated the association and interplay between musical instrument playing during life, multi-domain cognitive abilities and brain morphology in older adults from the DZNE-Longitudinal Cognitive Impairment and Dementia Study study. Participants reporting having played a musical instrument across three life periods were compared to controls without a history of musical instrument playing, well-matched for reserve proxies of education, (...) intelligence, socioeconomic status and physical activity. Participants with musical activity outperformed controls in global cognition, working memory, executive functions, language, and visuospatial abilities, with no effects seen for learning and memory. The musically active group had greater gray matter volume in the somatosensory area, but did not differ from controls in higher-order frontal, temporal, or hippocampal volumes. However, the association between gray matter volume in distributed frontal-to-temporal regions and cognitive abilities was enhanced in participants with musical activity compared to controls. We show that playing a musical instrument during life relates to better late-life cognitive abilities and greater brain capacities in OA. Musical activity may serve as a multimodal enrichment strategy that could help preserve cognitive and brain health in late life. Longitudinal and interventional studies are needed to support this notion. (shrink)

This book revives the study of conventional implicatures in natural language semantics. H. Paul Grice first defined the concept. Since then his definition has seen much use and many redefinitions, but it has never enjoyed a stable place in linguistic theory. Christopher Potts returns to the original and uses it as a key into two presently under-studied areas of natural language: supplements and expressives. The account of both depends on a theory in which sentence meanings can be multidimensional. The (...) theory is logically and intuitively compositional, and it minimally extends a familiar kind of intensional logic, thereby providing an adaptable, highly useful tool for semantic analysis. The result is a linguistic theory that is accessible not only to linguists of all stripes, but also philosophers of language, logicians, and computer scientists who have linguistic applications in mind. (shrink)

This wide-ranging introduction to classical Indian philosophy is philosophically rigorous without being too technical for beginners. Through detailed explorations of the full range of Indian philosophical concerns, including some metaphilosophical issues, it provides readers with non-Western perspectives on central areas of philosophy, including epistemology, logic, metaphysics, ethics, philosophy of language, and philosophy of religion. Chapters are structured thematically, with each including suggestions for further reading. This provides readers with an informed overview, whilst enabling them to focus on particular topics if (...) needed. Translated Sanskrit texts are accompanied by authorial explanations and contextualizations, giving the reader an understanding of the argumentative context and philosophical style of Indian texts. A detailed glossary and a guide to Sanskrit pronunciation equip readers with the tools needed for reading and understanding Sanskrit terms and names. The book will be an essential resource for both beginners and advanced students of philosophy and Asian studies. (shrink)

This article discusses the concept of mathematical metaphor as a tool for analyzing the formation of mathematical knowledge. It reflects on the work of Lakoff and Núñez as a reference point against which to rearticulate a richer notion of mathematical metaphor that can account for actual mathematical evolution. To reach its goal this article analyzes historical case studies, draws on cognitive research, and applies lessons from the history of metaphors in philosophy as analyzed by Derrida and de Man.

Reading Genesis 1 and 2, we are tempted to see only problems to solve. Yet these two chapters burst with glorious truths about God, our world, and ourselves. In fact, their foundational doctrines are among the richest sources of insight as we pursue robust, sensitive, and constructive engagement with others about contemporary culture and ideas. -/- With deftness and clarity, Christopher Watkin reclaims the Trinity and creation from their cultural despisers and shows how they speak into, question, and reorient (...) some of today's most important debates. (shrink)

At least since Locke, philosophers and psychologists have usually held that concepts arise out of sensory perceptions, thoughts are built from concepts, and language enables speakers to convey their thoughts to hearers. Christopher Gauker holds that this tradition is mistaken about both concepts and language. The mind cannot abstract the building blocks of thoughts from perceptual representations. More generally, we have no account of the origin of concepts that grants them the requisite independence from language. Gauker's alternative is to (...) show that much of cognition consists in thinking by means of mental imagery, without the help of concepts, and that language is a tool by which interlocutors coordinate their actions in pursuit of shared goals. Imagistic cognition supports the acquisition and use of this tool, and when the use of this tool is internalized, it becomes the very medium of conceptual thought. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:One True Ring or Many?Religious Pluralism in Lessing's Nathan the WiseChristopher AdamoIn the Central Scene of Nathan the Wise, Nathan responds to Saladin's pointed question pertaining to the "true religion" with the famous parable of the three rings.1 As John Pizer notes, Lessing deliberately crafts ambiguous fables to cultivate the reader's capacity for autonomous exercise of hermeneutic skill.2 That Gotthold Ephraim Lessing's Nathan the Wise evokes a wide variety (...) of interpretations, therefore, should be no surprise.3 However, for Pizer, Lessing's use of fable additionally represents a "key to his Enlightenment ideals, the inculcation of the idea that individuals are responsible for their own actions and for their own maturation as social beings, as later articulated by Kant" (Pizer, p. 101). If the genre of fable itself, for Lessing, serves as a pedagogic tool to cultivate in his readers the rational autonomy as envisioned by Kant in the opening lines of "What is Enlightenment?," then might that suggest Lessing's ring-parable is best read as an Enlightenment-humanist response to the theological and political problem of the plurality of revealed religions?Several recent Lessing scholars have taken this line. In his study Lessing's Philosophy of Religion and the German Enlightenment, Toshimasa Yasukata approvingly reads the parable of the rings as illustrative of Lessing's view of a "true religion" that "transcends all of the historical religions and yet underlies the truth of each.... [A] religion based on real and universal humanity."4 Astrid Oesmann, in her article "Nathan der Weise: Suffering Lessing's 'Erziehung,'" develops a similar interpretation but then, based upon it, turns a critical eye toward such a project as it requires Nathan to suppress his Judaic identity—not merely in his confrontation with Saladin but additionally by suppressing his suffering [End Page 139] at the hands of a Crusader pogrom that took the lives of his wife and seven children.5 For both these commentators, Lessing's Nathan the Wise champions a vision of a universal religion based on reason alone, for good or for ill.With this interpretation of Lessing's Nathan in the background, I intend to highlight moments in Lessing's Nathan that invite a more pluralistic reading. Both readings above interpret the ambiguous ending of the parable in light of the teleological history of revealed religion constructed by Lessing in "The Education of the Human Race" thus, implying there remains a singular, genuine, ring, i.e., a "true" religion that even may be identifiable with one of the three in question. The reading developed here interprets the ambiguous ending of the ring parable in light of the final scenes of Nathan, focusing on Recha's rich genealogical origins and her universal regard among persons of diverse faiths. The question as to which is the correct [recht] ring gives way to the question of which bearer(s) possesses a genuine [echt] ring, a significant shift in focus and reflective of Lessing's "primacy of ethics" over explanation in an approach to the plurality of revealed religions.6 Second, though both an Enlightenment reading and the present reading move the focus of religion away from orthodoxy towards a primacy of ethics, the present reading would be better equipped to respond to a charge like Oesmann's that defusing inter-religious tensions in a multicultural polity can come only by the sacrifice of one's cultural and historical particularity as Jewish, Muslim, Christian.INathan the Wise is set in Jerusalem during the close of the Third Crusade (1189–1192). A cease-fire has just been breached by the Knights Templar. Each side prepares to resume the hostilities. Previous acts of internecine violence reverberate throughout the play. Several of the play's characters suffer from (Nathan) and perpetrate (the Templar, the Sultan) sectarian violence. We discover in the first act that Saladin has just executed nineteen prisoners of war, sparing only one Templar. We discover in the fourth act that Nathan's entire family had been murdered by Crusaders roughly eighteen years previous. The political, pragmatic peace between rival parties is unraveling.The action begins when Nathan, a wealthy Jewish merchant, returns from his... (shrink)

We have developed a first generation tool for the unbiased identification and characterization of human pluripotent stem cells, termed PluriTest. This assay utilizes all the information contained on a microarray and abandons the conventional stem cell marker concept. Stem cells are defined by the ability to replenish themselves and to differentiate into more mature cell types. As differentiation potential is a property that cannot be directly proven in the stem cell state, biologists have to rely on correlative measurements in stem (...) cells associated with differentiation potential. Unfortunately, most, if not all, of those markers are only valid within narrow limits of specific experimental systems. Microarray technologies and recently next‐generation sequencing have revolutionized how cellular phenotypes can be characterized on a systems‐wide level. Here we discuss the challenges PluriTest and similar global assays need to address to fulfill their enormous potential for industrial, diagnostic and therapeutic applications. (shrink)

Recent work in argumentation theory has emphasized the nature of arguers and arguments along with various theoretical perspectives. Less attention has been given to the third feature of any argumentative situation - the audience. This book fills that gap by studying audience reception to argumentation and the problems that come to light as a result of this shift in focus. Christopher W. Tindale advances the tacit theories of several earlier thinkers by addressing the central problems connected with audience considerations (...) in argumentation, problems that earlier philosophical theories overlook or inadequately accommodate. The main tools employed in exploring the central issues are drawn from contemporary philosophical research on meaning, testimony, emotion and agency. These are then combined with some of the major insights of recent rhetorical work in argumentation to advance our understanding of audiences and suggest avenues for further research. (shrink)

This chapter focuses on the views of Australian philosopher-physicist Ernst Mach, the earliest and most systematic writer on thought experiments. It discusses Mach's response to the problem of informativeness. It then details the book's disagreements with Mach. It is argued that Mach's mistakes can be traced to his sensationalism and a one-sided diet of examples. His sensationalism led him to overemphasize the mentalistic aspects of thought experiment and to throw away tools needed to explain its genuinely a priori features. Perhaps (...) because of this, Mach's attention gravitated toward thought experiments he could explain and away from the recalcitrant normative examples. To get a complete account of thought experiments, we should reject sensationalism and consider how armchair inquiry works in general. (shrink)

Germline Gene Editing has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, GGE has been strongly resisted. In this article, we analyse the ethical arguments for and against pursuing GGE by allowing and funding its development. We argue there is a strong case for pursuing GGE for the prevention of disease. We then examine objections that have been raised against pursuing GGE and argue that these fail. We conclude (...) that the moral case in favour of pursuing GGE is stronger than the case against. This suggests that pursuing GGE is morally permissible and indeed morally desirable. (shrink)

The normative notion of fittingness figures saliently in the work of a number of ethical theorists writing in the late nineteenth and mid-twentieth centuries and has in recent years regained prominence, occupying an important place in the theoretical tool kits of a range of contemporary writers. Yet the notion remains strikingly undertheorized. This article offers a (partial) remedy. I proceed by canvassing a number of attempts to analyze the fittingness relation in other terms, arguing that none is fully adequate. In (...) explaining why various analyses of fittingness fail, I draw into relief certain of the relation’s constitutive features and spotlight some of its interesting and important connections to various other properties. Along the way, I highlight the relation’s relevance to a number of ongoing debates in normative and metanormative philosophy. I conclude by indicating some directions for further research. (shrink)

“Probabilistic Causation” designates a group of theories that aim to characterize the relationship between cause and effect using the tools of probability theory. The central idea behind these theories is that causes change the probabilities of their effects. This article traces developments in probabilistic causation, including recent developments in causal modeling. A variety of issues within, and objections to, probabilistic theories of causation will also be discussed.

Contemporary recognition theory has developed powerful tools for understanding a variety of social problems through the lens of misrecognition. It has, however, paid somewhat less attention to how to conceive of appropriate responses to misrecognition, usually making the tacit assumption that the proper societal response is adequate or proper affirmative recognition. In this paper I argue that, although affirmative recognition is one potential response to misrecognition, it is not the only such response. In particular, I would like to make the (...) case for derecognition in some cases: derecognition, in particular, through the systematic deinstitutionalization or uncoupling of various reinforcing components of social institutions, components whose tight combination in one social institution has led to the misrecognition in the first place. I make the case through the example of recent United States debates over marriage, especially but not only with respect to gay marriage. I argue that the proper response to the misrecognition of sexual minorities embodied in exclusively heterosexual marriage codes is not affirmative recognition of lesbian and gay marriages, but rather the systematic derecognition of legal marriage as currently understood. I also argue that the systematic misrecognition of women that occurs under the contemporary institution of marriage would likewise best be addressed through legal uncoupling of heterogeneous social components embodied in the contemporary social institution of marriage. (shrink)

Engineering the Climate: The Ethics of Solar Radiation Management is a wide-ranging and expert analysis of the ethics of the intentional management of solar radiation. This book will be a useful tool for policy-makers, a provocation for ethicists, and an eye-opening analysis for both the scientist and the general reader with interest in climate change.

Many environmental ethicists believe that any adequate environmental ethic should attribute ‘direct moral standing’ to plants, animals, and the rest of nature. But certain interpretations of Hindu environmental ethics apparently attribute only instrumental value to nature. This places them in direct conflict with the purported adequacy condition on an environmental ethic. So, is such a Hindu ethical view really inadequate? In his recent book Hinduism and Environmental Ethics, Christopher Framarin claims that it is because Hindu instrumentalism about nature is (...) either viciously circular or unacceptably arbitrary. I argue, however, that Framarin’s claim founders in virtue of his misconstruing the logical structure of instrumental value. (shrink)

Engineering the Climate: The Ethics of Solar Radiation Management is a wide-ranging and expert analysis of the ethics of the intentional management of solar radiation. This book will be a useful tool for policy-makers, a provocation for ethicists, and an eye-opening analysis for both the scientist and the general reader with interest in climate change.

Background: Smart sensors have been developed as diagnostic tools for rehabilitation to cover an increasing number of geriatric patients. They promise to enable an objective assessment of complex movement patterns. -/- Objective: This research aimed to identify and analyze the conflicting ethical values associated with smart sensors in geriatric rehabilitation and provide ethical guidance on the best use of smart sensors to all stakeholders, including technology developers, health professionals, patients, and health authorities. -/- Methods: On the basis of a systematic (...) literature search of the scientific databases PubMed and ScienceDirect, we conducted a qualitative document analysis to identify evidence-based practical implications of ethical relevance. We included 33 articles in the analysis. The practical implications were extracted inductively. Finally, we carried out an ethical analysis based on the 4 principles of biomedical ethics: autonomy, beneficence, nonmaleficence, and justice. The results are reported in categories based on these 4 principles. -/- Results: We identified 8 conflicting aims for using smart sensors. Gains in autonomy come at the cost of patient privacy. Smart sensors at home increase the independence of patients but may reduce social interactions. Independent measurements performed by patients may result in lower diagnostic accuracy. Although smart sensors could provide cost-effective and high-quality diagnostics for most patients, minorities could end up with suboptimal treatment owing to their underrepresentation in training data and studies. This could lead to algorithmic biases that would not be recognized by medical professionals when treating patients. -/- Conclusions: The application of smart sensors has the potential to improve the rehabilitation of geriatric patients in several ways. It is important that patients do not have to choose between autonomy and privacy and are well informed about the insights that can be gained from the data. Smart sensors should support and not replace interactions with medical professionals. Patients and medical professionals should be educated about the correct application and the limitations of smart sensors. Smart sensors should include an adequate representation of minorities in their training data and should be covered by health insurance to guarantee fair access. (shrink)

Thought uses meaning but not necessarily language. Meaning, in the form of a set of possible concepts and ideas, is a nonphysical reality that lay waiting for brains to become smart enough to represent these ideas. Thus, the brain evolved, whereas meaning was discovered, and language was invented – collectively – as a tool to help the brain use meaning.