Evolutionary Transitions in Individuality have been responsible for the major transitions in levels of selection and individuality in natural history, such as the origins of prokaryotic and eukaryotic cells, multicellular organisms, and eusocial insects. The integrated hierarchical organization of life thereby emerged as groups of individuals repeatedly evolved into new and more complex kinds of individuals. The Social Protocell Hypothesis proposes that the integrated hierarchical organization of human culture can also be understood as the outcome of an ETI—one that produced (...) a “cultural organism” from a substrate of socially learned traditions that were contained in growing and dividing social communities. The SPH predicts that a threshold degree of evolutionary individuality would have been achieved by 2.0–2.5 Mya, followed by an increasing degree of evolutionary individuality as the ETI unfolded. We here assess the SPH by applying a battery of criteria—developed to assess evolutionary individuality in biological units—to cultural units across the evolutionary history of Homo. We find an increasing agreement with these criteria, which buttresses the claim that an ETI occurred in the cultural realm. (shrink)

L'A. s'attache à étudier l'expérience de la temporalité dans la philosophie heidéggerienne de l'existence : elle prend la structure d'un être-avec repensé à neuf par Heidegger après le tournant visant à surmonter la métaphysique de la représentation et du sens et cherchant à atteindre l'Etre pur. L'A. montre le déploiement de cette pensée dans l'analyse existentielle.

BACKGROUND: Reasoning biases have been suggested as risk factors for delusional ideation in both patients and non-clinical individuals. Still, it is unclear how these biases are longitudinally related to delusions in the general population. We hence aimed to investigate longitudinal associations between reasoning biases and delusional ideation in the general population. METHODS: We conducted an online cohort study with 1184 adults from the German and Swiss general population. Participants completed measures on reasoning biases (jumping-to-conclusion bias JTC, liberal acceptance bias LA, (...) bias against disconfirmatory evidence BADE, possibility of being mistaken PM) and delusional ideation at baseline, and delusional ideation 7 to 8 months later. RESULTS: A greater JTC bias was associated with a greater increase in delusional ideation over the following months. This association was better described by a positive quadratic relationship. Neither BADE, LA nor PM were associated with subsequent changes in delusional ideation. CONCLUSIONS: This study suggests that jumping-to-conclusions predicts delusional ideation in the general population but that this association may follow a quadratic trajectory. While no other associations turned significant, future studies with shorter temporal distances may shed further light on the role of reasoning biases as risk factors for delusional ideation in non-clinical samples. (shrink)

L'A. élabore une pensée ontologique basée sur une phénoménologie du besoin inspirée de Heidegger, S. Weil et Claude Bruaire. En partant du dépassement heideggérien de la métaphysique classique, complété par l'idée de Bruaire d'une onto-do-logie centrée sur le besoin auto-affectif et la pensée de S.Weil selon laquelle le désir du Bien absolu réside dans notre être charnel, l'A. présente le besoin comme étant révélation d'absolu et oubli représentatif absolu.

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

We apply an online optimization process based on machine learning to the production of Bose-Einstein condensates. BEC is typically created with an exponential evaporation ramp that is optimal for ergodic dynamics with two-body s-wave interactions and no other loss rates, but likely sub-optimal for real experiments. Through repeated machine-controlled scientific experimentation and observations our ’learner’ discovers an optimal evaporation ramp for BEC production. In contrast to previous work, our learner uses a Gaussian process to develop a statistical model of the (...) relationship between the parameters it controls and the quality of the BEC produced. We demonstrate that the Gaussian process machine learner is able to discover a ramp that produces high quality BECs in 10 times fewer iterations than a previously used online optimization technique. Furthermore, we show the internal model developed can be used to determine which parameters are essential in BEC creation and which are unimportant, providing insight into the optimization process of the system. (shrink)

The problem of free will lies at the heart of modern scientific studies of consciousness. Some authors propose that actions are unconsciously initiated and awareness of intention is referred retrospectively to the action after it has been performed [e.g. Aarts, H., Custers, R., & Wegner, D. M. . On the inference of personal authorship: Enhancing experienced agency by priming effect information. Consciousness & Cognition, 14, 439–458]. This contrasts with the common impression that our intentions cause those actions. By combining a (...) stop signal paradigm and an intentional action paradigm we show that participants sometimes indicate to have intentionally initiated an action while reaction time data strongly suggest that they in fact failed to stop the action. In a second experiment we demonstrate that the number of trials in which participants misattributed their awareness of intention varied with the intentional involvement during action planning. Our data support the retrospective account of intentional action. Furthermore, we introduce an experimental approach that objectifies introspective judgments of awareness of intention. (shrink)

L’utilisation des données des plus grands catalogues électroniques des bibliothčques allemandes concernant les éditions des ouvrages de Franjo Petrić et leurs exemplaires permet d’arriver ŕ des résultats qu’il serait probablement impossible d’obtenir par d’autres moyens et instruments. Il existe de fortes indications qui montrent que la réception allemande de Petrić antérieure au XXe siecle diffčre sensiblement de sa réception dans d’autres pays . A ce stade-lŕ de réception, l’impact des ses Discussiones peripateticae et Militia romana est particuličrement évident. Les résultats (...) concernant l’impact des éditions de 1952 et postérieures different ŕ maints égards de ceux obtenus pour les éditions antérieures. Cet article est une étude de cas préliminaire utilisant, ŕ des fins de comparaison, des données puisées dans des sources britanniques et dans la banque de données AHCI. (shrink)

Scientific authority and physician authority are both challenged by Thomas Kuhn's concept of incommensurability. If competing “paradigms” or “world views” cannot rationally be compared, we have no means to judge the truth of any particular view. However, the notion of local or partial incommensurability might provide a framework for understanding the implications of contemporary philosophy of science for medicine. We distinguish four steps in the process of translating medical science into clinical decisions: the doing of the science, the appropriation (...) of the scientific findings by the clinician, the transfer of the findings from the clinician to the patient, and the choice of a treatment regimen. Incommensurability can play a role in each stage. There is at least some theory- and value-ladenness in science that is dependent on the world view of those who construct the scientific theories. Clinicians who must use the results of scientific research will inevitably interpret the research from the standpoint of their own world view. There may be further incommensurability when these data are communicated to the patient. Finally, clinician and patient values must come into play in any decision about choice of treatment. No stage of medical research or practice is value-free. This position does not imply relativism; some scientific accounts are better than others. However, the challenge of the incommensurabilists shows that further analysis is needed to establish how particular accounts are better or worse. (shrink)