Explorations of different philosophies of science, their (metaphysical, epistemological, ontological and other assumptions).These are the institutionalized empiricist approaches and the post-cognitive ones, but still anthropo-centered and (inter) subject-oriented ones. Their pre-suppositions are identified and alternatives are suggested.

A paramount, yet unresolved issue in personalised medicine is that of automated reasoning with clinical guidelines in multimorbidity settings. This entails enabling machines to use computerised generic clinical guideline recommendations and patient-specific information to yield patient-tailored recommendations where interactions arising due to multimorbidities are resolved. This problem is further complicated by patient management desiderata, in particular the need to account for patient-centric goals as well as preferences of various parties involved. We propose to solve this problem of automated reasoning with (...) interacting guideline recommendations in the context of a given patient by means of computational argumentation. In particular, we advance a structured argumentation formalism ABA+G (short for Assumption-Based Argumentation with Preferences (ABA+) and Goals) for integrating and reasoning with information about recommendations, interactions, patient’s state, preferences and prioritised goals. ABA+G combines assumption-based reasoning with preferences and goal-driven selection among reasoning outcomes. Specifically, we assume defeasible applicability of guideline recommendations with the general goal of patient well-being, resolve interactions (conflicts and otherwise undesirable situations) among recommendations based on the state and preferences of the patient, and employ patient-centered goals to suggest interaction-resolving, goal-importance maximising and preference-adhering recommendations. We use a well-established Transition-based Medical Recommendation model for representing guideline recommendations and identifying interactions thereof, and map the components in question, together with the given patient’s state, prioritised goals, and preferences over actions, to ABA+G for automated reasoning. In this, we follow principles of patient management and establish corresponding theoretical properties as well as illustrate our approach in realistic personalised clinical reasoning scenaria. (shrink)

The paper examines the epistemological side of the Laclau’s political theory, incorporating tools that aim to convert discourse theory into a rigorous, useful, and valid method for socio-political and critical analysis in social sciences. In the first part, it displays some epistemological assumptions and arguments. The second part analyses some problematic epistemological aspects derived from the arguments. The proposal is based on Laclau’s main texts, complementing the analysis with related tools from critical hermeneutics and existential phenomenology. It is argued that (...) the incorporation of these tools to political discourse analysis contribute to solve some of the methodological and epistemic deficits of the theory of hegemony. El trabajo examina el plano epistemológico de la teoría política de Ernesto Laclau, aportando herramientas que tienen por objeto convertir a la teoría del discurso en un método riguroso, útil y válido para el análisis sociopolítico y crítico en ciencias sociales. En la primera parte, despliega una serie de postulados y presupuestos epistémicos. En la segunda parte, analiza algunos aspectos gnoseológicos problemáticos que se derivan de los postulados. Para desarrollar la propuesta, se toman como base los principales textos de Laclau, complementando el análisis con herramientas afines provenientes de la hermenéutica crítica y la fenomenología existencialista. Se sostiene que la incorporación de estas herramientas al análisis político del discurso contribuye a resolver algunos de los déficits metodológicos y epistémicos que presenta la teoría de la hegemonía. (shrink)

Philosophy of the Social Sciences, Volume 51, Issue 6, Page 574-599, December 2021. In “Different Cultures, Different Rationalities” Stephen Lukes weighs in on the controversies concerning the killing of Captain Cook by Hawaiians and what it says about the role of rationality assumptions in translation. While at first seeming to adopt a Davidsonian anti-relativist position concerning the enabling role of assumptions of common rationality in interpretation, Lukes rejects Davidson’s view, and opts instead for a “totalizing” strategy inspired by Mauss. Here (...) I explore rationales for Lukes’ position and endeavor to reconcile Lukes’, Davidson’s, and Mauss’s positions by developing a case for a limited interpretive requirement of shared rationality. (shrink)

Charney's dismissal of well-established methods in behavioral genetic research is misguided. He claims that studies of heritability and genetic association depend for their validity on six assumptions, but he cites no sources to support this claim. We explain why none of the six assumptions is strictly necessary for the utility of either method of genetic analysis.

Although in some contexts the notions of an ordinary argument’s presumption, assumption, and presupposition appear to merge into the one concept of an implicit premise, there are important differences between these three notions. It is argued that assumption and presupposition, but not presumption, are basic logical notions. A presupposition of an argument is best understood as pertaining to a propositional element (a premise or the conclusion) e of the argument, such that the presupposition is a necessary condition for (...) the truth of e or for a term in e to have a referent. In contrast, an assumption of an argument pertains to the argument as a whole in that it is integral to the reasoning or inferential structure of the argument. A logical assumption of an argument is essentially a proposition that must be true in order for the argument aside from that proposition to be fully cogent. Nothing that is both comparable and distinguishing can be said about presumptions of arguments. Rather, presumptions of arguments are distinctively conventional; they are introduced through conventional rules (e.g., those that concern how to treat promises). So not all assumptions and not all presuppositions of arguments are presumptions of those arguments, although all presumptions of arguments are either assumptions or presuppositions of those arguments. This account avoids making the (monological) notion of presumption vacuous and dissolving the distinction between assumption and presumption, which is a vulnerability of alternative views such as Hansen’s and Bermejo-Luque’s, as is shown. (shrink)

We offer thoughts on Shadmehr and Ahmed's foundational assumption that behavioral intensity (vigor) is proportional to the perceived value of outcomes driving behavior (incentives). The assumption is reasonable considering classical motivational thought and scholarship in related literatures but called into question by an influential contemporary theory of motivation by Brehm. Brehm's theory suggests that the assumption is warranted in some, but not all, performance circumstances. Furthermore, proportionality between vigor and value might be generated through a deliberative goal-setting (...) process rather than through intrinsic neural linkages. (shrink)

What is difficult to imagine is also surprising to perceive. This indicates that active visual imagery is an integral part of active visual perception. Erroneous mental transformations provide clues to prior assumptions in visual imagery, just as visual illusions provide clues to perceptual assumptions. Visual imagery and perception share generic assumptions about invariants in images of rigid objects.

With the widespread infusion of online technology there has been an increase in various studies investigating the practices in online communities including also philosophical perspectives. What those debates have in common is that they call for more critical thinking about the theory of online communication. Drawing on Techno-Anthropological research perspectives, our interest is placed on exploring and identifying human interactions and technology in intersectional spaces. This article explores information systems that allow for interchanges of different users. We discuss ontological assumptions (...) that focus on understanding the kind of dialogue that can be captured between different expert groups when they utilize information systems. We present the notion of ‘dialogic’ by Mikhail Bakhtin and contextualize it through an analysis of online dialogue. Dialogic or ‘conversation and inquiry’ is discussed as being mediated through human relationships. Acknowledging the existence of at least two voices the underlying differences between dialogue partners are highlighted. (shrink)

John Bell showed that a big class of local hidden-variable models stands in conflict with quantum mechanics and experiment. Recently, there were suggestions that empirically adequate hidden-variable models might exist which presuppose a weaker notion of local causality. We will show that a Bell-type inequality can be derived also from these weaker assumptions.

As a positive thesis, philosophical anarchism claims that political authority is always at odds with practical rationality insomuch as authoritative directives are best analysed as content-independent reasons. The aim of this paper is to clarify the metaethical assumptions behind such a claim. Since philosophical anarchists reject as irrational the possibility that an agent can follow content-independent reasons issued by another agent, emphasising agents’ responsibility to assess the content of every directive before acting in conformity with it, it is safe to (...) say that philosophical anarchists must be cognitivist in metaethics. At the very least, were there no right or wrong answers to questions such as “what does one have reason to do in these circumstances?”, answers such as “one should follow authoritative directives” would be as good as any other. However, philosophical anarchism requires much more than metaethical cognitivism; indeed, it requires a very specific (and ambitious) type of cognitivism. I intend to show which one. (shrink)

Multiverses are predictions based on theories. Focusing on each theory’s assumptions is key to evaluating a proposed multiverse. Although accepted theories of particle physics and cosmology contain non-intuitive features, multiverse theories entertain a host of “strange” assumptions classified as metaphysical topics such as: infinity, duplicate yous, hypothetical fields, more than three space dimensions, Hilbert space, advanced civilizations, and reality established by mathematical relationships. It is easy to confuse multiverse proposals because many divergent models exist. This overview defines the characteristics of (...) eleven popular multiverse proposals. The characteristics compared are: initial conditions, values of constants, laws of nature, number of space dimensions, number of universes, and fine tuning explanations. Future scientific experiments may validate selected assumptions; but until they do, proposals by philosophers may be as valid as theoretical scientific theories. (shrink)

This paper addresses the question of what existential assumptions are needed for the Aristotelian interpretation of the relationships between the four categorical propositions. The particular relationships in question are those unique to the Aristotelian logic, namely, contrariety, subcontrariety, subaltemation, conversion by limitation, and contraposition by limitation. The views of several recent authors of logic textbooks are surveyed. While most construe the Aristotelian logic as capable of being preserved by assuming that the subject class has a member, Irving Copi construes that (...) logic as requiring that four assumptions about class membership be made. These are that the subject, predicate, complement of subject, and complement of predicate classes all have members. It is argued that only three assumptions about class membership are needed, viz., that subject, predicate, and complement of predicate classes have members. (shrink)

This paper considers two subjective measures of the existence of unconscious mental states - the guessing criterion, and the zero correlation criterion - and considers the assumptions underlying their application in experimental paradigms. Using higher order thought theory the impact of different types of biases on the zero correlation and guessing criteria are considered. It is argued that subjective measures of consciousness can be biased in various specified ways, some of which involve the relation between first order states and second (...) order thoughts, and hence are not errors in measurement of the conscious status of mental states; but other sorts of biases are measurement errors, involving the relation between higher order thoughts and their expression. Nonetheless, it is argued this type of bias does not preclude subjective measures - both the guessing criterion and the zero correlation criterion - as being amongst the most appropriate and useful tools for measuring the conscious status of mental states. (shrink)

Reichle et al. specify two assumptions as being basic to E-Z Reader: Words are sequentially attended during fixations, and saccades are triggered by a cognitive event. We point out that there is little evidence for the first assumption and counterevidence for the second. Also, the labile/nonlabile stage distinction in saccade preparation seems to be contrary to current evidence. An alternative explanation of saccade onset times in reading assumes that saccades are strategically generated, independent of language processing, but are delayed (...) on a probabilistic basis by processing difficulties. (shrink)

SummaryThe working logician begins with whatever operations are necessary to make computation possible. He does not inquire into the foundations which the carrying out of his operations assumes; no axioms, no assumptions, just the computations themselves. Yet in logic of all places the starting‐point should be defensible. After examining the logical assumptions, the constructions of proofs, individuals and classes, and the metaphysical assumptions, the conclusion is reached that the net effect of operational logic is to assimilate logic to mathematics rather (...) than to consider mathematics an extension of logic. The price to be paid for this preference is to leave them both unexplained. It would mean that the metaphysics of mathematics would have to proceed without logic. (shrink)

This 2007 article (based around an invited conference talk at Wayne State in early 2007) addresses risk assessment and cost benefit analysis as mechanisms in counterterrorism policy. It argues that although policy is often best pursued by agreeing to set aside deep foundational differences, in order to obtain a strategic plan for an activity such as counterterrorism, foundational differences must be addressed in order that policy not merely devolve into a policy minimalism that is always and damagingly tactical, never strategic, (...) in order to avoid domestic democratic political conflict. The article takes risk assessment in counterterrorism, using cost benefit analysis, as an example of a foundational disagreement that cannot easily be elided. Examining an extreme, indeed crude, recent example of cost benefit analysis applied to the risks of terror and the costs of counterterrorism - John Mueller's widely noticed Overblown - the article suggests that cost benefit analysis, at least applied in this way, runs roughshod over other important values in counterterrorism policy, such as justice, but in addition, makes radical yet unstated assumptions about what cost benefit analysis seeks to compare in establishing counterterrorism policy or estimating the risks and costs of terrorism - unstated assumptions that, in fact, assume the conclusion. The article notes that cost benefit analysis tends to promote a policy-minimalizing "event specific catastrophism" - seeking above all to prevent simply the next, serial terrorist attack, with however no greater strategic vision. Indeed, the article says in conclusion (as Philip Bobbitt has noted) cost benefit analysis is "relentlessly tactical," not strategic; it also tends toward serial 'event specific catastrophism' as its analytic frame; and it is a method of evaluating proposed courses of action, not generating them, and hence promotes a strategically questionable tendency to reaction as a response to terrorism. This article presents these ideas in brief fashion, however, as the first draft in a larger project on cost benefit analysis and counterterrorism, and it does so by reference to a book that is unabashedly crude in its approach to both cost benefit analysis and terrorism/counterterrorism. The critical project will extend beyond this particular article, which is in effective a a first pass at developing a critique. It is also an article that does not extend beyond events of early 2007 (when the original address was given) and should be read in that light. (shrink)

One of the most widely used procedures applied to non-human animals or pre-linguistic humans is the “violation of expectation paradigm”. Curiously there is almost no discussion in the philosophical literature about it. Our objective will be to provide a first approach to the meta-theoretical nature of the assumptions behind the procedure that appeals to the violation of expectation and to extract some consequences. We show that behind them exists an empirical principle that affirms that the violation of the expectation of (...) certain mental rules generates surprise. We then proceeded to discuss the nature of these “mental rules”. We show that, as is often the case with theoretical concepts proposed by theories, they do not have a fixed interpretation. This will allow us to show that the usual relationship found in the developmental psychology literature between this experimental paradigm and cognitive approaches (which interpret experimental results in terms of higher-level mental activities) is not necessary. Finally, we relate this experimental design with the mark test and the inequity aversion test and discuss the possible ampliation of the application of the empirical principle of violation of expectation. (shrink)

Abstract Noting that the use of modern instruments of war had unpredictable and revolutionary consequences, Morris Janowitz introduced the concept of a ?constabulary force? to show how a professional military in a liberal democratic state might use modern weapons and yet conserve the existing political order. This article explores the meaning of this concept in three ways. First, it examines the strategic assumptions underlying the concept to explain why Janowitz thought it offered an approach to containing the revolutionary consequences of (...) the use of force that was more promising than alternative concepts of military force. Second, it explores the moral implications of the concept (which Janowitz did not do), identifying key moral commitments a constabulary force must meet to sustain a liberal democratic order as it attempts to resolve dilemmas posed by the use of force. Third, it considers in what way these moral commitments are particular to a constabulary force, while yet preserving an approach to the use of force that could be applied across the spectrum of force by military structures of various kinds. (shrink)

This essay discusses a core tenet of pessimism, Afropessimism, in particular. Pessimism claims to be a metatheory analyzing the assumptive logics of the system it critiques. Afropessimists hold that a logical treatment of pessimism is unwarranted because pessimism does not employ a logical treatment of its object. We’ll discuss Afropessimism and, by extension, pessimism, in general, on their own terms as metatheory. We’ll see that a metatheory indirectly follows the logic its object follows directly. From this, a metatheory must hold (...) an assumptive logic of its own, even if superficially disavowed. Consequently, we’ll arrive at a puzzling result when, in this particular case, the metatheory’s claims empty its object of its content, hence the pessimism. (shrink)

John Bell showed that a big class of local hidden-variable models stands in conflict with quantum mechanics and experiment. Recently, there were suggestions that empirically adequate hidden-variable models might exist which presuppose a weaker notion of local causality. We will show that a Bell-type inequality can be derived also from these weaker assumptions. IntroductionThe EPR-Bohm experimentLocal causalityBell's inequality from separate common causes4.1 A weak screening-off principle4.2 Perfect correlation and ‘determinism’4.3 A minimal theory for spins4.4 No conspiracyDiscussion.

It is not uncommon for patients with advanced disease to express a wish to hasten death. Qualitative studies of the WTHD have found that such a wish may have different meanings, none of which can be understood outside of the patient’s personal and sociocultural background, or which necessarily imply taking concrete steps to ending one’s life. The starting point for the present study was a previous systematic review of qualitative studies of the WTHD in advanced patients. Here we analyse in (...) greater detail the statements made by patients included in that review in order to examine their moral understandings and representations of illness, the dying process and death. We identify and discuss four classes of assumptions: assumptions related to patients’ moral understandings in terms of dignity, autonomy and authenticity; assumptions related to social interactions; assumptions related to the value of life; and assumptions related to medicalisation as an overarching context within which the WTHD is expressed. Our analysis shows how a philosophical perspective can add to an understanding of the WTHD by taking into account cultural and anthropological aspects of the phenomenon. We conclude that the knowledge gained through exploring patients’ experience and moral understandings in the end-of-life context may serve as the basis for care plans and interventions that can help them experience their final days as a meaningful period of life, restoring some sense of personal dignity in those patients who feel this has been lost. (shrink)

This paper evaluates the economic assumptions of economic theory via an examination of the capitalist transformation of creditor–debtor relations in the 18th century. This transformation enabled masses of people to obtain credit without moral opprobrium or social subordination. Classical 18th century economics had the ethical concepts to appreciate these facts. Ironically, contemporary economic theory cannot. I trace this fault to its abstract representations of freedom, efficiency, and markets. The virtues of capitalism lie in the concrete social relations and social meanings (...) through which capital and commodities are exchanged. Contrary to laissez faire capitalism, the conditions for sustaining these concrete capitalist formations require limits on freedom of contract and the scope of private property rights. (shrink)

Assumption of risk - the notion that one cannot complain about a harmful state to which one has willingly exposed oneself - figures prominently in our extra-legal lived experience. In spite of its deep roots in our common-sense morality, the tort doctrine of assumption of risk has long been discredited by many leading tort scholars, restatement reporters, courts, and legislatures. In recent years, however, growing concerns about junk food consumption, and about obesity more generally, have given rise to (...) considerations that are traditionally associated with the principles underlying the doctrine of assumption of risk. Against this backdrop, I shall advance two claims: one negative and the other affirmative. The negative claim is that the major objections to the doctrine of assumption of risk are either misplaced or overblown. And affirmatively, I argue that this doctrine can provide an illuminating framework with which to address pressing social concerns such as the one associated with junk food’s harmful side-effects. (shrink)

Contributors to the debate on ethical rationing bring with them assumptions about the proper role of moral theories in practical discourse, which seem reasonable, realistic and pragmatic. These assumptions function to define the remit of bioethical discourse and to determine conceptions of proper methodology and causal reasoning in the area. However well intentioned, the desire to be realistic in this sense may lead us to judge the adequacy of a theory precisely with reference to its ability to deliver apparently determinate (...) answers to questions that strike most practitioners and patients as morally arbitrary. By providing ethical solutions that work given the world as it is, work in clinical ethics may serve to endorse or protect from scrutiny the very structures that need to change if real moral progress is to be possible. Such work can help to foster the illusion that fundamentally arbitrary decisions are ‘grounded’ in objective, impartial reasoning, bestowing academic credibility on policies and processes, making it subsequently harder for others to criticise those processes. As theorists, we need to reflect on our political role and how best to foster virtuous, critical practice, if we are to avoid making contributions to the debate that not only do no good, but may even be harmful. A recent debate in this journal illustrates these issues effectively. (shrink)

Ethical concerns about randomising persons to a no-treatment arm in the context of Ebola epidemic led to consideration of alternative designs. The stepped wedge design, in which participants or clusters are randomised to receive an intervention at different time points, gained popularity. Common arguments in favour of using this design are when an intervention is likely to do more good than harm, all participants should receive the experimental intervention at some time point during the study and the design might be (...) preferable for practical reasons. We examine these assumptions when considering Ebola vaccine research. First, based on the claim that a stepped wedge design is indicated when it is likely that the intervention will do more good than harm, we reviewed published and ongoing SW trials to explore previous use of this design to test experimental drugs or vaccines, and found that SW design has never been used for trials of experimental drugs or vaccines. Given that Ebola vaccines were all experimental with no prior efficacy data, the use of a stepped wedge design would have been unprecedented. Second, we show that it is rarely true that all participants receive the intervention in SW studies, but rather, depending on certain design features, all clusters receive the intervention. Third, we explore whether the SW design is appealing for feasibility reasons and point out that there is significant complexity. In the setting of the Ebola epidemic, spatiotemporal variation may have posed problematic challenges to a stepped wedge design for vaccine research. Finally, we propose a set of points to consider for scientific reviewers and ethics committees regarding proposals for SW designs. (shrink)

In their book EVALUATING CRITICAL THINKING Stephen Norris and Robert Ennis say: “Although it is tempting to think that certain [unstated] assumptions are logically necessary for an argument or position, they are not. So do not ask for them.” Numerous writers of introductory logic texts as well as various highly visible standardized tests (e.g., the LSAT and GRE) presume that the Norris/Ennis view is wrong; the presumption is that many arguments have (unstated) necessary assumptions and that readers and test takers (...) can reasonably be expected to identify such assumptions. This paper proposes and defends criteria for determining necessary assumptions of arguments. Both theoretical and empirical considerations are brought to bear. (shrink)

The most common argument against the use of rational choice models outside economics is that they make unrealistic assumptions about individual behavior. We argue that whether the falsity of assumptions matters in a given model depends on which factors are explanatorily relevant. Since the explanatory factors may vary from application to application, effective criticism of economic model building should be based on model-specific arguments showing how the result really depends on the false assumptions. However, some modeling results in imperialistic applications (...) are relatively robust with respect to unrealistic assumptions. Key Words: unrealistic assumptions • economics imperialism • rational choice • as if • robustness. (shrink)

Proofs from assumptions are amongst the most fundamental reasoning techniques. Yet the precise nature of assumptions is still an open topic. One of the most prominent conceptions is the placeholder view of assumptions generally associated with natural deduction for intuitionistic propositional logic. It views assumptions essentially as holes in proofs, either to be filled with closed proofs of the corresponding propositions via substitution or withdrawn as a side effect of some rule, thus in effect making them an auxiliary notion subservient (...) to proper propositions. The Curry–Howard correspondence is typically viewed as a formal counterpart of this conception. I will argue against this position and show that even though the Curry–Howard correspondence typically accommodates the placeholder view of assumptions, it is rather a matter of choice, not a necessity, and that another more assumption-friendly view can be adopted. (shrink)

Proof-theoretic semantics is an inferentialist theory of meaning, usually developed in a multiple-assumption and single-conclusion framework. In that framework, this theory seems unable to justify classical logic, so some authors have proposed a multiple-conclusion reformulation to accomplish this goal. In the first part of this paper, the debate originated by this proposal is briefly exposed and used to defend the diverging opinion that proof-theoretic semantics should always endorse a single-assumption and single-conclusion framework. In order to adopt this approach (...) some of its _criteria_ of validity, especially separability, need to be weakened. This choice is evaluated and defended. The main argument in this direction is based on the circular dependences of meaning between multiple assumptions and conjunctions, and between multiple conclusions and disjunctions. In the second part of this paper, some systems that suit the new requirements are proposed for both intuitionistic and classical logic. A proof that they are valid, according to the weakened _criteria_, is sketched. (shrink)

Institute of Theoretical Physics, Exact Sciences Sidlerstrasse 5, University of Bern, CH-3012 Bern Switzerland portmann{at}itp.unibe.ch' + u + '@' + d + ''//--> awuethr{at}itp.unibe.ch' + u + '@' + d + ''//--> John Bell showed that a big class of local hidden-variable models stands in conflict with quantum mechanics and experiment. Recently, there were suggestions that empirically adequate hidden-variable models might exist which presuppose a weaker notion of local causality. We will show that a Bell-type inequality can be derived also (...) from these weaker assumptions. Introduction The EPR-Bohm experiment Local causality Bell's inequality from separate common causes 4.1 A weak screening-off principle 4.2 Perfect correlation and ‘determinism’ 4.3 A minimal theory for spins 4.4 No conspiracy Discussion. (shrink)

This volume explores assumptions and frameworks concerning violence, nonviolence, war, conflict, and reconciliation, and considers what would be needed in order for people to see nonviolence as a viable approach to contemporary problems.

A research community must share assumptions, such as about accepted knowledge, appropriate research practices, and good evidence. However, community members also hold some divergent assumptions, which they—and we, as analysts of science—tend to overlook. Communities with different assumed values, knowledge, and goals must negotiate to achieve compromises that make their conflicting goals complementary. This negotiation guards against the extremes of each group’s desired outcomes, which, if achieved, would make other groups’ goals impossible. I argue that this diversity, as a form (...) of value pluralism, regularly influences scientific practice and can make scientific evidence and knowledge more useful and more reliable. As an example, I examine vertebrate paleontology laboratories, which house a variety of workers with different training and priorities, particularly about the meaning of time. Specifically, scientists want to study fully prepared fossils immediately, conservators want to preserve fossils for future use, and preparators mediate between the other groups’ conflicting goals. After all, one cannot study a fossil encased in rock, and one cannot remove that rock without removing information from that specimen. In response, these coworkers articulate their assumptions in everyday deliberations about how scientific evidence should be made and used. I argue that this exchange of assumptions is crucial for a research community to achieve mutually beneficial compromises that benefit current and future knowledge construction. (shrink)

Scientific risk evaluations are constructed by specific evidence, value judgements and biological background assumptions. The latter are the framework-setting suppositions we apply in order to understand some new phenomenon. That background assumptions co-determine choice of methodology, data interpretation, and choice of relevant evidence is an uncontroversial claim in modern basic science. Furthermore, it is commonly accepted that, unless explicated, disagreements in background assumptions can lead to misunderstanding as well as miscommunication. Here, we extend the discussion on background assumptions from basic (...) science to the debate over genetically modified (GM) plants risk assessment. In this realm, while the different political, social and economic values are often mentioned, the identity and role of background assumptions at play are rarely examined. We use an example from the debate over risk assessment of stacked genetically modified plants (GM stacks), obtained by applying conventional breeding techniques to GM plants. There are two main regulatory practices of GM stacks: (i) regulate as conventional hybrids and (ii) regulate as new GM plants. We analyzed eight papers representative of these positions and found that, in all cases, additional premises are needed to reach the stated conclusions. We suggest that these premises play the role of biological background assumptions and argue that the most effective way toward a unified framework for risk analysis and regulation of GM stacks is by explicating and examining the biological background assumptions of each position. Once explicated, it is possible to either evaluate which background assumptions best reflect contemporary biological knowledge, or to apply Douglas' 'inductive risk' argument. (shrink)

Psychiatric genetic research investigates the genetic basis of psychiatric disorders with the aim of more effectively understanding, treating, or, ultimately, preventing such disorders. Given the challenges of recruiting research participants into such studies, the potential for long‐term benefits of such research, and seemingly minimal risk, a strong claim could be made that all non‐acute psychiatric inpatients, including forensic and involuntary patients, should be included in such research, provided they have capacity to consent. There are tensions, however, regarding the ethics of (...) recruiting psychiatric inpatients into such studies. In this paper our intention is to elucidate the source of these tensions from the perspective of research ethics committee interests and decision‐making. We begin by defining inpatient status and outline some of the assumptions surrounding the structures of inpatient care. We then introduce contemporary conceptions of vulnerability, including Florencia Luna’s account of vulnerability which we use as a framework for our analysis. While psychiatric inpatients could be subject to consent‐related vulnerabilities, we suggest that a particular kind of exploitation‐related vulnerability comes to the fore in the context of our case study. Moreover, a subset of these ethical concerns takes on particular weight in the context of genetic research in low‐ and middle‐income countries. At the same time, the automatic exclusion of inpatients from research elicits justice‐related vulnerabilities. (shrink)

Name der Zeitschrift: Semiotica Jahrgang: 2016 Heft: 209 Seiten: 15-30.

Most current theoretical models of dreaming are built around an assumption that dream reports collected on awakening provide unbiased sampling of previous cognitive activity during sleep. However, such data are retrospective, requiring the recall of previous mental events from sleep on awakening. Thus, it is possible that dreaming occurs throughout sleep and differences in subsequent dream reports are owing to systematic differences in our ability to recall mentation on awakening. For this reason, it cannot be concluded with certainty that (...) sleep cognition is more predominant or in any way different during REM compared to NREM sleep. It is our contention that REM sleep and ponto-geniculo-occipital (PGO) waves do not necessarily represent stimulation of the cortex in the generation of dreams, but might rather represent enhanced arousal of attention mechanisms during sleep, which results in the subsequent recall of attended mentation on awakening. (shrink)

Pierre Olivier distinguishes between two radically different concep-tions of legal fictions: on the one hand, the conception of legal fiction developed by the commentators of the Middle Ages, which culminates in Bartolus’s defini-tion; on the other hand, the conception developed by the 19th Century German scholar Gustav Demelius, who was followed, among others, by Joseph Esser. The main difference between the two approaches is individuated by Olivier in the fact that, while the former consider legal fictions as essentially implying an (...) actual fic-tional element, the latter deny this. In other words, according to Demelius and those who follow him, the term “legal fiction” is a misnomer. In this article, I first provide an example of a legal fiction. In the second and third section, I rely on this example to analyze and assess the two competing accounts. Finally, in the fourth part, I advance a syncretistic account of legal fictions, which should thus point to a possible middle ground between the two competing positions. As it is often the case, there is probably some truth to both accounts; the problem – I will argue – is that both theories tell only a part and not the whole of the story. More precisely, it will be argued that legal fictions essentially involve the structure of “as if”-statements, and that the one-sidedness of the two competing accounts derives from the fact that one focuses too much on the “if”-component (the assumption), whereas the other focuses too much on the “as”-component (the comparison). (shrink)