Used wisely the concepts of race and ethnicity in research have great potential, but used unwisely they can do immense damage. We need to consider the potential issues that might require a change of emphasis or application of ethics in a multi-ethnic society. Doing no harm is the most important ethical pillar in the ethnicity and health field. Ethnic differences can be used in damaging ways. Without the ethic of beneficence in place it is better not to draw attention to (...) ethnic differences. Respect is the pre-condition for autonomy. Autonomy of ethnic minority populations to live in their own traditional way is not easy to achieve in multi-ethnic societies. There are difficult issues in multi-ethnic societies that require great sensitivity to create a sense of fairness and justice. Justice is the core value that underpins equity. There is a deep paradox – to promote equality, we may need to treat people and groups unequally. Ethical codes need to be modified to emphasize the importance of including ethnic minority populations in research and not bypassing them, as has been happening. It is correct, for example, that potential research participants' personal details are guarded. If such a person, however, does not read it may be unethical to send written information about a project. It may be more ethical to tele phone or even call at the doorstep of such a person. The history of racism in research is worrying, not least the fear that it might return. We need a governing code of conduct. Ethical research can help ethnic minority groups to move from the shadows of society and participate in a vibrant, healthy, multi-ethnic society. (shrink)

Numerous studies have shown almost uniformly positive opinions among patients and physicians regarding theconceptof advance directives (either a healthcare proxy or living will). Several of these studies have also shown that the actual use of advance directives is significantly lower than this enthusiasm would suggest, but they have not explained the apparent discordance. Nor have researchers explained why members of minority groups are much less likely to complete advance directives than are white patients. In this study, we used a (...) class='Hi'>focus group methodology to examine the ways in which diverse populations of patients view the medical, philosophical, and practical issues surrounding advance directives. We were motivated by the significantly lower prevalence of advance directives among African-American and Hispanic patients at one urban teaching hospital (18% for Caucasians, 4% for African-Americans, and 2% for Hispanics). Our premise was that African-American and Hispanic populations, who have had higher rates of morbidity and mortality across numerous disease categories, and historically have had limited access to care and opportunities to discuss health concerns, may be more suspicious about the right of autonomy that an advance directive is designed to ensure. (shrink)

Numerous studies have shown almost uniformly positive opinions among patients and physicians regarding theconceptof advance directives (either a healthcare proxy or living will). Several of these studies have also shown that the actual use of advance directives is significantly lower than this enthusiasm would suggest, but they have not explained the apparent discordance. Nor have researchers explained why members of minority groups are much less likely to complete advance directives than are white patients. In this study, we used a (...) class='Hi'>focus group methodology to examine the ways in which diverse populations of patients view the medical, philosophical, and practical issues surrounding advance directives. We were motivated by the significantly lower prevalence of advance directives among African-American and Hispanic patients at one urban teaching hospital (18% for Caucasians, 4% for African-Americans, and 2% for Hispanics). Our premise was that African-American and Hispanic populations, who have had higher rates of morbidity and mortality across numerous disease categories, and historically have had limited access to care and opportunities to discuss health concerns, may be more suspicious about the right of autonomy that an advance directive is designed to ensure. (shrink)

This paper demonstrates that the property of Replication Invariance, generally considered to be an innocuous requirement for the extension of fixed-population poverty comparisons to variable-population contexts, is incompatible with other plausible variable- and fixed-population axioms. This fact raises questions about what constitutes an appropriate headcount assessment of poverty, in terms of whether one should focus on the proportion, or the absolute numbers, of the population in poverty. This observation, in turn, has important implications for tracking (...) poverty and setting targets for its reduction or elimination. (shrink)

This paper focuses on the relations between population ethics and metaethics. Population ethics gives rise to well-known paradoxes, such as the paradox of mere addition. After presenting a version of this paradox, it is argued that a different way to dismantle it might be by considering it as a way to change our standard view of justification in moral theory. Two possible views are considered: a non-cognitivist approach to justification and to the explanation of inconsistency in morals; Parfit's (...) suggestion that certain paradoxes might be «quarantined» without shaking our confidence in moral theories encapsulating them. (shrink)

The dissertation is a critical examination of theory evaluation in population genetics. There are three main philosophical approaches to theory evaluation in philosophy of science: confirmation and hypothesis testing, scientific change, and experimentation. Accounts that champion each of the main philosophical approaches to scientific theory evaluation are represented in philosophy of biology: confirmation and hypothesis testing by Elisabeth A. Lloyd, scientific change by Lindley Darden, and experimentation by David W. Rudge. I argue that each of the main approaches is (...) insufficient for evaluating population genetics theories. However, the accounts I critique are not fundamentally incompatible. I modify, unify, and extend them into a comprehensive account of theory evaluation for population genetics. ;My philosophical analysis is driven by a complex, important, and ongoing controversy in population genetics, viz., the R. A. Fisher-Sewall Wright controversy in population genetics. I use my historical case study to assess the adequacy of both the extant philosophical analyses of theory evaluation and my own account. Between 1929 and 1962 Fisher and Wright debated the main differences emanating from their alternative approaches to evolutionary theorizing. The debates between Fisher and Wright functionally ended with Fisher's death. However, Wright continued to clarify his position in the controversy until his death in 1988, and other biologists have continued work on the core debates. ;Recently, four scientific papers led by biologists Jerry A. Coyne and Michael J. Wade have been key in revisiting and rekindling the Fisher-Wright controversy with analyses of old theoretical and empirical issues as well as new developments that have spun off the older work. Four decades after the debates between Fisher and Wright, these papers have staked out, with substantial disagreement, claims about the evaluative status of the two predominant population genetics approaches to evolution in the field. A further task of this dissertation is to provide a non-partisan evaluation of the last 40 years of work on the controversy, i.e., the controversy since Fisher's death in 1962. It is hoped that such a critical analysis of the controversy will advance it to some extent. (shrink)

Human population genetic research (HPGR) seeks to identify the diversity and variation of the human genome and how human group and individual genetic diversity has developed. This book asks whether developing countries are well prepared for the ethical and legal conduct of human population genetic research, with specific regard to vulnerable target group protection. The book highlights particular issues raised by genetic research on populations as a whole, such as the capacity for current frameworks of Western developed countries (...) to provide adequate protections for target groups in human population genetic research, and explores potential groups of people that may suffer harm in this kind of research. Using The People's Republic of China as a key example, Yue Wang argues that since the target groups of HPGR are almost always vulnerable groups from isolated and rural areas of developing countries, the ethical and legal frameworks for human subject protection need to be reconsidered in order to eliminate, or at least reduce, the vulnerability of those groups. While most research in this field focuses on the impact on individuals, this book breaks new ground in exploring how the interests of target groups are also seriously implicated in genetic work. The book argues that current regulations are far from sufficient to prevent harm to vulnerable groups and puts forward an alternative model for group protection in the context of human population genetic research in developing countries. The book will be of great interest to students and academics of medical law, ethics, and the implications of genetic research. (shrink)

The debate between the Mendelians and the (largely Darwinian) biometricians has been referred to by R. A. Fisher as ‘one of the most needless controversies in the history of science’ and by David Hull as ‘an explicable embarrassment’. The literature on this topic consists mainly of explaining why the controversy occurred and what factors prevented it from being resolved. Regrettably, little or no mention is made of the issues that figured in its resolution. This paper deals with the latter topic (...) and in doing so reorients the focus of the debate as one between Karl Pearson and R. A. Fisher rather than between the biometricians and the Mendelians. One reason for this reorientation is that Pearson's own work in 1904 and 1909 suggested that Mendelism and biometry could, to some extent, be made compatible, yet he remained steadfast in his rejection of Mendelism. The interesting question then is why Fisher, who was also a proponent of biometric methods, was able to synthesise the two traditions in a way that Pearson either could not or would not. My answer to this question involves an analysis of the ways in which different kinds of assumptions were used in modelling Mendelian populations. I argue that it is these assumptions, which lay behind the statistical techniques of Pearson and Fisher, that can be isolated as the source of Pearson's rejection of Mendelism and Fisher's success in the synthesis. (shrink)

Nowadays, around half of the global population lives in urban areas. This rate is expected to increase up to two-thirds by the year 2050. Most studies analyze urban dynamics in wide geographic ranges, focusing mainly on cities. According to them, the global population is spatially distributed in two extremes: large urban agglomerations and rural deserts. However, this remark is excessively general and imprecise. For this reason, it remains essential to analyze these dynamics at other spatial scales. A close-up (...) look in thinly populated regions shows how urban dynamics are also noticeable. In this paper, we analyze spatiotemporal patterns of population distribution in a predominantly rural area by applying a local-scale approach. These patterns are represented by using spatial networks with nodes representing the human settlements and links showing hierarchies between nodes. This case study is conducted in a small municipality located in northwestern Spain. It is a predominantly rural area with a very particular spatial pattern of population distribution. (shrink)

Every year, millions of people are affected by disasters and atrocities. Violent and disastrous life events can have significant effects on a person’s physical and psychological wellbeing. Post-tra...

Wildlife populations in the northern reaches of the globe have long been observed to fluctuate or cycle periodically, with dramatic increases followed by catastrophic crashes. Focusing on the early work of Charles S. Elton, this article analyzes how investigations into population cycles shaped the development of Anglo-American animal ecology during the 1920s–1930s. Population cycling revealed patterns that challenged ideas about the “balance” of nature; stimulated efforts to quantify population data; and brought animal ecology into conversation with intellectual (...) debates about natural selection. Elton used the problem of understanding wildlife population cycles to explore a central tension in ecological thought: the relative influences of local conditions (food supply, predation) and universal forces (such as climate change and natural selection) in regulating wild animal populations. He also sought patronage and built research practices and the influential Bureau of Animal Population around questions of population regulation during the 1930s. Focusing on disease as a local population regulator that could interact with global climatic influences, Elton facilitated an interdisciplinary and population-based approach in early animal ecology. Elton created a network of epidemiologists, conservationists, pathologists and mathematicians, who contributed to population cycle research. I argue that, although these people often remained peripheral to ecology, their ideas shaped the young discipline. Particularly important were the concepts of abundance, density, and disease; and the interactions between these factors and natural selection. However, Elton’s reliance on density dependence unwittingly helped set up conditions conducive to the development of controversies in animal ecology in later years. While ecologists did not come to consensus on the ultimate causes of population cycles, this phenomenon was an important early catalyst for the development of theory and practice in animal ecology. (shrink)

From the 1960s, mathematical and computational tools have been developed to arrive at human population trees from various kinds of serological and molecular data. Focusing on the work of the Italian-born population geneticist Luigi Luca Cavalli-Sforza, I follow the practices of tree-building and mapping from the early blood-group studies to the current genetic admixture research. I argue that the visual language of the tree is paralleled in the narrative of the human diasporas, and I show how the tree (...) was actually mapped onto the surface of the earth. This visual and textual structure is mirrored in the liberal discourse of unity in diversity that has been criticized as running counter to the socio-political effects of human population genetics. From this perspective, one may ask how far the phylogenetic diagram in its various forms is a manifestation of the physics of power that according to Michel Foucault consists in mechanisms that analyse distributions, movements, series, combinations, and that uses instruments to render visible, to register, to differentiate and to compare. It is one among other disciplinary technologies that ensure the ordering of human diversity. In the case of intra-human phylogenetic trees, population samples and labels are one issue. Another is that the separated branches seem to show groups of people, who have in reality been interacting and converging, as isolated. Often based on so-called isolated peoples, molecular tree diagrams freeze a hierarchical kinship system that is meant to represent a state before the great historical population movements. (shrink)

This paper criticizes non-constructive uses of set theory in formal economics. The main focus is on results on preference aggregation and Arrow’s theorem for infinite electorates, but the present analysis would apply as well, e.g., to analogous results in intergenerational social choice. To separate justified and unjustified uses of infinite populations in social choice, I suggest a principle which may be called the Hildenbrand criterion and argue that results based on unrestricted axiom of choice do not meet this criterion. (...) The technically novel part of this paper is a proposal to use a set-theoretic principle known as the axiom of determinacy ), not as a replacement for Choice, but simply to eliminate applications of set theory violating the Hildenbrand criterion. A particularly appealing aspect of \ from the point of view of the research area in question is its game-theoretic character. (shrink)

This article is about ‘genogeographic’ maps produced by late-Soviet geneticists and published during post-Soviet time. It focuses on the visual and numerical techniques scientists used to project genetic data onto geographic space. Rather than discussing their representational character, I follow these visuals as ‘folded objects’, describing the layering and realigning of measurements and temporalities as well as the shifts in the practices and meanings of genetics. In the 1970s Soviet biological anthropologists transformed scattered data points by means of spatial statistics (...) into visually coherent maps for a ‘genogeographical atlas’, by interpolating data for the entire USSR territory. Computer-aided modelling rendered ‘populations’ as systemic entities and enacted specific cybernetic versions of population, evolution and difference. Tracing the history of their making helps one in understanding what these folded objects hold in store, in terms of data ranging from Russian imperial and colonial anthropology, through early Soviet traditions, to cold war technologies. Folded into those maps in intricate ways, they have co-shaped post-Soviet human genetics as an ever-active site for possible reinscriptions of difference. (shrink)

Explaining the persistence of populations is an important quest in ecology, and is a modern manifestation of the balance of nature metaphor. Increasingly, however, ecologists see populations (and ecological systems generally) as not being in equilibrium or balance. The portrayal of ecological systems as “non-equilibrium” is seen as a strong alternative to deterministic or equilibrium ecology, but this approach fails to provide much theoretical or practical guidance, and warrants formalisation at a more fundamental level. This is available in adaptation theory, (...) which allows population persistence to be explained as an epiphenomenon stemming from the maintenance, survival, movement and reproduction of individual organisms. These processes take place within a physicochemical and biotic environment that persists through structured annual cycles, but which is also spatiotemporally dynamic and subject to stochastic variation. The focus is thus shifted from the overproduction of offspring and the consequent density dependent population pressure thought to follow, to the adaptations and ecological circumstances that support those relatively few individuals that do survive. (shrink)

How do we characterize theoretical disagreement and how does this translate into strategies for practicing scientists? I integrate Kuhn’s (1962) notions of paradigms and problem-fields with Hull’s (1982,1988) concept of populational variation and Shapere’s (1974) characterization of domains in interpreting the Ox-Phos Controversy in bioenergetics (1961-1977). The analysis highlights the differences between intraparadigm disagreement (based on proposed solutions to shared problems) and interparadigm disagreement (based on the problems themselves and views of relevant domain).Kuhn (1959,1962) introduced the notion that a single, (...) uniform paradigm guides ‘normal science’. He further suggested that scientific communities undergo gestalt-like changes in research focus, implying that all disagreement is based on ‘incommensurable’ paradigms. Philosophers and historians of science concerned largely with how consensus is established (see Laudan 1984; Laudan and Laudan 1989) have found this problematic as a universal model (e.g., Lakatos and Musgrave 1970; Laudan 1977). (shrink)

The genetic revolution is well underway, with genetic research and knowledge expanding at an exponential rate. Much of the new genetics research is focused on population groups, and proponents of “population genomics” argue that such studies are necessary since genetic “variation” among human populations holds the most promise for technological innovations that can improve human health and lead to increased understanding of the origin of human populations. Population genomic research thus targets specific groups to discover variation that (...) could lead to knowledge about genetic disorders, possible cures, and the origin and migration patterns of distinctive peoples. Research on genetic differences among groups or populations, however, raises many pressing ethical and legal questions. For example, focus on biological differences of racial and ethnic groups has in the past lead to assumptions about superiority and inferiority between groups, and in practice resulted in stigmatization and discrimination. Consequently, attention on groups should raise legal and moral red flags and compel us to move cautiously in this area. Pragmatically, targeting population groups as the object of study requires the determination of the nature and scope of “population groups” for purposes of genetics research. (shrink)

This anthology collects some of the most important papers on what is believed to be the major force in evolution, natural selection. An issue of great consequence in the philosophy of biology concerns the levels at which, and the units upon which selection acts. In recent years, biologists and philosophers have published a large number of papers bearing on this subject. The papers selected for inclusion in this book are divided into three main sections covering the history of the subject, (...) explaining its conceptual foundations, and focusing on kin and group selection and higher levels of selection.One of the book's interesting features is that it draws together material from the biological and philosophical literatures. The philosophical literature, having thoroughly absorbed the biological material, now offers conceptual tools suitable for the reworking of the biological arguments. Although a full symbiosis has yet to develop, this anthology offers a unique resource for students in both biology and philosophy.Robert N. Brandon is Professor in the Philosophy Department, Duke University. Richard M. Burian is Professor of Philosophy and Department Chairman, Virginia Polytechnic Institute and State University.A Bradford Book. (shrink)

This is a review of contemporary philosophical discussions of population policies. The focus is on normative justification, and the main question is whether population policies can be ethically justified. Although few analytical philosophers have directly addressed this question – it has been discussed more in other academic fields – many arguments and considerations can be placed in the analytical philosophical discourse. This article offers a comprehensive review and analysis of ethically relevant aspects of population policies evaluated (...) on the basis of the main ethical theories. This analysis is preceded by a brief historical contextualisation of when and how population policies became ethically contentious and how this relates to philosophical debates in environmental ethics, population ethics and political philosophy. The article also includes a conceptual analysis of population policies in which the empirical intricacies around individual fertility decisions are sorted out and the different ways in which they can be affected are categorised in a taxonomy which highlight the most relevant ethical aspects of population policies. The ethical analysis shows that while population policies can be justified on the basis of most ethical theories, it all depends on what prior assumptions are made about what is at stake. (shrink)

Bioethics' traditional focus on clinical relationships and exotic technologies has led the field away from population health, health disparities, and issues of justice. The result: a myopic view that misses the institutional context in which clinical relationships operate and can overlook factors that affect health more broadly than do exotic technologies. A broader bioethics agenda would take up unresolved questions about the distribution of health and the development of fair policies that affect health distribution.

In this special issue we explore practices of scientific inquiry into human populations in Latin America in order to generate new insights into the complex historical and sociopolitical dynamics that have made certain human groups integral to the production of scientific knowledge in and about the region. In important contributions, other scholars have shown that the science of human difference is racist and all too often has been a mediator of development ideologies. To further unpack these arguments we focus (...) attention on the complex interaction between scientists and the populations they study. We explore cases from across the fields of evolutionary biology, demography, epidemiology... (shrink)

This article adopts a population-level bioethics approach to analyzing the ethical implications of novel deep-brain stimulation (DBS) technologies. I claim that a microlevel focus on costs and benefits is necessary but insufficient to address the concerns of social justice and health equity that attend the potential utilization of DBS technologies. A macrosocial, population-based analysis notes two ethically significant trends regarding novel health technologies: (1) that they are the prime mover of hyperinflationary health cost trajectories, and (2) that (...) even where they improve overall population health such technologies may expand health inequalities. Such an expansion could exacerbate what Powers and Faden have identified as “densely-woven patterns of disadvantage,” and therein could contravene mandates of social justice. Such concerns of justice and equity are sharpened by the fact that those populations that bear the highest risk of suffering the injuries and illnesses for which DBS technologies might be warranted are among the most disadvantaged groups in American society. Accordingly, ethical analysis of DBS technologies must include an assessment of the evidence suggesting that in their capacity to improve health and compress health inequalities, whole-population approaches that address the upstream factors that shape distributions of neuropsychiatric injuries and illness may be preferable to acute health interventions. However, the article warns against the false-choice fallacy, and notes that whole-population policies and acute care interventions can be simultaneously endorsed. The article concludes by suggesting that the ethical issue of relative priority between these approaches is best framed via a population-level analysis. (shrink)

A path scheme for a game is composed of a path, i.e., a sequence of coalitions that is formed during the coalition formation process and a scheme, i.e., a payoff vector for each coalition in the path. A path scheme is called population monotonic if a player’s payoff does not decrease as the path coalition grows. In this study, we focus on Shapley path schemes of simple games in which for every path coalition the Shapley value of the (...) associated subgame provides the allocation at hand. Obviously, each Shapley path scheme of a game is population monotonic if and only if the Shapley allocation scheme of the game is population monotonic in the sense of Sprumont (Games Econ Behav 2:378–394, 1990). We prove that a simple game allows for population monotonic Shapley path schemes if and only if the game is balanced. Moreover, the Shapley path scheme of a specific path is population monotonic if and only if the first winning coalition that is formed along the path contains every minimal winning coalition. We also show that each Shapley path scheme of a simple game is population monotonic if and only if the set of veto players of the game is a winning coalition. Extensions of these results to other efficient probabilistic values are discussed. (shrink)

Global human population expansion is rooted in a remarkably successful evolutionary innovation. The neolithic transformation of the natural world gave rise to a symbiosis between humans and their domesticated plant and animal partners that will expand from a current 20 per cent to 60 percent of terrestrial biomass by the middle of the coming century. Such an increase must necessarily be accompanied by a concomitant decrease in wildlife biomass. We suggest that current trends in population growth are unlikely (...) to abate for three reasons: first, there are intrinsic biological pressures to reproduce regardless of social engineering; second, the character of the domestic alliance makes it a formidable competitor to wildlife; and third, the timeframe before population doubling is, from a biological perspective, virtually instantaneous. This paper draws from a wide body of research in the biological and social sciences. We neither condone nor endorse this picture of inexorable population increase. Rather, we appeal for a change in the nature of the discussion of population among environmentalists, to focus on the question of how best to manage what wildlife will be left on the margins of a domesticated world. (shrink)

A deflationary perspective on theories of cultural evolution, in particular dual-inheritance theory, has recently been proposed by Lewens. On this ‘pop-culture’ analysis, dual-inheritance theorists apply population thinking to cultural phenomena, without claiming that cultural items evolve by natural selection. This paper argues against this pop-culture analysis of dual-inheritance theory. First, it focuses on recent dual-inheritance models of specific patterns of cultural change. These models exemplify population thinking without a commitment to natural selection of cultural items. There are grounds, (...) however, for doubting the added explanatory value of the models in their disciplinary context—and thus grounds for engaging in other potentially explanatory projects based on dual-inheritance theory. One such project is suggested by advocates of the theory. Some of the motivational narratives that they offer can be interpreted as setting up an adaptationist project with regard to cumulative change in cultural items. We develop this interpretation here. On it, dual-inheritance theory features two interrelated selection processes, one on the level of genetically inherited learning mechanisms, another on the level of the cultural items transmitted through these mechanisms. This interpretation identifies a need for further modelling efforts, but also offers scope for enhancing the explanatory power of dual-inheritance theory. (shrink)

This study explored drug users’ attitudes toward and understanding of randomized controlled trials testing addiction therapies. A video portraying a fictional consent conference for a randomized controlled trial with placebo arm was shown to poor male and female drug users of diverse ethnic status and sexual orientation. The video stimulated focus group discussion in which participants’ comments often reflected “experimental realism”—a realistic view of the trial—and adequate understanding of the uncertain efficacy of the treatment being tested, as well as (...) the concepts of randomization and placebo control. However, participants’ comprehension of the nature of placebos was compromised by the widespread view that placebos are a way of testing a subject’s willpower and personal control over his or her addiction. Comments also showed a mistrust of the video investigator’s integrity and competence and signs of therapeutic misconception and misestimation. The study’s findings underscore the importance of tailoring informed consent encounters to the personal and sociohistorical context of participants’ lived experiences. (shrink)

We study the coupled dynamics of two populations of random replicators by means of statistical mechanics methods, and focus on the effects of relative population size, strategy correlations and heterogeneities in the respective cooperation pressures. To this end we generalise existing path-integral approaches to replicator systems with random asymmetric couplings. This technique allows one to formulate an effective dynamical theory, which is exact in the thermodynamic limit and which can be solved for persistent order parameters in a fixed-point (...) regime regardless of the symmetry of the interactions. The onset of instability can be determined self-consistently. We calculate quantities such as the diversity of the respective populations and their fitnesses in the stationary state, and compare results with data from a numerical integration of the replicator equations. -/- . (shrink)

During the past few decades, philosophers of biology have debated the issue of reductionism versus anti-reductionism, with both sides often claiming a ‘pluralist’ position. However, both sides also tend to focus on a single research paradigm, which analyzes living things in terms of certain macromolecular components. I offer a case study where biologists pursue other analytic pathways, in a tradition of quantitative genetics that originates with the initially purely mathematical theories of R. A. Fisher, J. B. S. Haldane, and (...) Sewall Wright in the 1930s. Aster Models offers a class of statistical models designed for studying the fitness of plant and animal populations, by integrating the measurements of separate, sequential, non-normally distributed fitness components in novel ways. Their work generates important theoretical and practical results that do not require elaboration by molecular biology, and thus serves as a counterexample to the claims of philosophers whose ‘pluralism’ still harbors reductionist assumptions. (shrink)

The dynamics of neural populations capture the laws of the mindThis paper focuses on the level of neural networks. Examining the case of recurrent neural networks, the paper argues that the dynamics of neural populations form a privileged level of explanation in cognitive science. According to Schöner, this level is privileged, because it enables cognitive scientists to discover the laws governing organisms’ cognition and behaviour.

Philosophical discussions of prioritarianism, the view that we ought to give priority to those who are worse off, have hitherto been almost exclusively focused on cases involving a fixed population. The aim of this paper is to extend the discussion of prioritarianism to encompass also variable populations. I argue that prioritarianism, in its simplest formulation, is not tenable in this area. However, I also propose several revised formulations that, so I argue, show more promise.

We examine a general class of variable-value population principles. Our particular focus is on the extent to which such principles can avoid the repugnant and sadistic conclusions. We show that if a mild limit property is imposed, avoidance of the repugnant conclusion implies the sadistic conclusion. This result generalizes earlier observations by showing that they apply to a substantially larger class of principles. Our second theorem states that, under the limit property, the axiom of mere addition also conflicts (...) with avoidance of the repugnant conclusion. This result is a consequence of a similar observation that appears in the earlier literature. (shrink)

Interest among historians, philosophers and sociologists of science in population-based biomedical research has focused on the randomised controlled trial to the detriment of the longitudinal study, the temporally extended, serial observation of individuals residing in the same community. This is perhaps because the longitudinal study is regarded as having played a secondary role in the debates about the validity of populations-based approaches that helped to establish epidemiology as one of the constitutive disciplines of contemporary biomedicine. Drawing on archival data (...) and publications relating to the Baltimore Longitudinal Study of Aging, we argue however that the historical development of the longitudinal study is richer and more significant than has been appreciated. We argue that this history is shaped by the tension between two sets of epistemic practices, devices and norms. On the one side there were those who emphasised randomisation and sampling to evidence claims about, and justify policies with respect to, the aetiology of disease. On the other side there were those who evoked the technical repertoire of physiological research, especially the notion of the ‘model organism’, to argue for a different integration of the individual in modern society. (shrink)

Group-structured populations, of the kind prominent in discussions of multilevel selection, are contrasted with ‘neighbor-structured’ populations. I argue that it is a necessary condition on multilevel description of a selection process that there should be a nonarbitrary division of the population into equivalence classes (or an approximation to this situation). The discussion is focused via comparisons between two famous problem cases involving group structure (altruism and heterozygote advantage) and two neighbor-structured cases that resemble them. Conclusions are also drawn about (...) the role of correlated interaction in the evolution of altruism. 1 Introduction 2 Two Kinds of Population Structure 3 Objections and Replies 4 Particles on a Line 5 Conclusion Appendix: Neighborhoods and Selection CiteULike Connotea Del.icio.us What's this? (shrink)

It is notoriously difficult to find an intuitively satisfactory rule for evaluating populations based on the welfare of the people in them. Standard examples, like total utilitarianism, either entail the Repugnant Conclusion or in some other way contradict common intuitions about the relative value of populations. Several philosophers have presented formal arguments that seem to show that this happens of necessity: our core intuitions stand in contradiction. This paper assesses the state of play, focusing on the most powerful of these (...) ‘impossibility theorems’, as developed by Gustaf Arrhenius. I highlight two ways in which these theorems fall short of their goal: some appeal to a supposedly egalitarian condition which, however, does not properly reflect egalitarian intuitions; the others rely on a background assumption about the structure of welfare which cannot be taken for granted. Nonetheless, the theorems remain important: they give insight into the difficulty, if not perhaps the impossibility, of constructing a satisfactory population axiology. We should aim for reflective equilibrium between intuitions and more theoretical considerations. I conclude by highlighting one possible ingredient in this equilibrium, which, I argue, leaves open a still wider range of acceptable theories: the possibility of vague or otherwise indeterminate value relations. (shrink)

The concept of difference has a long and important research tradition. We identify and explicate a heretofore overlooked distinction in the meaning and measurement of two different meanings of 'difference': 'diversity' and 'heterogeneity'. We argue that ‘diversity’ can describe a population well enough but does not describe a collective well. In contrast, ‘heterogeneity’ describes a collective better than a population and therefore ought to describe a collective. We argue that ignoring these distinctions can lead to a surprising and (...) disturbing conflict between diversity and heterogeneity. In particular, focusing on the 'diversity' of human communities can be self-defeating for those who truly care about the importance of diversity, inclusion, and belonging. (shrink)

Economics and social sciences in general have a long tradition of using theories, models, concepts, and so forth borrowed from the natural sciences to describe and explain the properties and behaviours of economic and social entities. However, unwarranted application of theoretical elements from the natural sciences in the economic/social domain can have adverse consequences for organisations, their employees and society in general. Focusing on biology and organisation studies, we discuss the general problems that may arise when theoretical elements from natural (...) science are applied in the economic/social domain. We examine one particular case, the organisational ecology research programme, and we argue that organisational ecology rests on the metaphorical, rather than literal, use of the notion of evolution. We conclude by showing how the use of the evolutionary metaphor in organisation theory can have adverse consequences for both managerial practice and society in general. (shrink)

The standard mathematical models in population ecology assume that a population's growth rate is a function of its environment. In this paper we investigate an alternative proposal according to which the rate of change of the growth rate is a function of the environment and of environmental change. We focus on the philosophical issues involved in such a fundamental shift in theoretical assumptions, as well as on the explanations the two theories offer for some of the key (...) data such as cyclic populations. We also discuss the relationship between this move in population ecology and a similar move from first-order to second-order differential equations championed by Galileo and Newton in celestial mechanics. (shrink)

ArgumentMoreau (2019) has raised concerns about the use of DNA data obtained from vulnerable populations, such as the Uighurs in China. We discuss another case, situated in Europe and with a research history dating back 100 years: genetic investigations of Roma. In our article, we focus on problems surrounding representativity in these studies. We claim that many of the circa 440 publications in our sample neglect the methodological and conceptual challenges of representativity. Moreover, authors do not account for problematic (...) misrepresentations of Roma resulting from the conceptual frameworks and sampling schemes they use. We question the representation of Roma as a “genetic isolate” and the underlying rationales, with a strong focus on sampling strategies. We discuss our results against the optimistic prognosis that the “new genetics” could help to overcome essentialist understandings of groups. (shrink)

BackgroundHumanitarian crises and emergencies, events often marked by high mortality, have until recently excluded palliative care—a specialty focusing on supporting people with serious or terminal illness or those nearing death. In the COVID-19 pandemic, palliative care has received unprecedented levels of societal attention. Unfortunately, this has not been enough to prevent patients dying alone, relatives not being able to say goodbye and palliative care being used instead of intensive care due to resource limitations. Yet global guidance was available. In 2018, (...) the WHO released a guide on‘Integrating palliative care and symptom relief into the response to humanitarian emergencies and crises’—the first guidance on the topic by an international body.AimsThis paper argues that while a landmark document, the WHO guide took a narrowly clinical bioethics perspective and missed crucial moral dilemmas. We argue for adding a population-level bioethics lens, which draws forth complex moral dilemmas arising from the fact that groups having differential innate and acquired resources in the context of social and historical determinants of health. We discuss dilemmas concerning: limitations of material and human resources; patient prioritisation; euthanasia; and legacy inequalities, discrimination and power imbalances.ImplicationsIn parts of the world where opportunity for preparation still exists, and as countries emerge from COVID-19, planners must consider care for the dying. Immediate steps to support better resolutions to ethical dilemmas of the provision of palliative care in humanitarian and emergency contexts will require honest debate; concerted research effort; and international, national and local ethical guidance. (shrink)

Population policy has taken two divergent trajectories. In the developing part of the world, controlling population growth has been a major tune of the debate more than a half-century ago. In the more developed part of the world, an inverse pattern results in the discussion over the facilitation of population growth. The ethical debates on population policy have primarily focused on the former and ignored the latter. This paper proposes a more comprehensive account that justifies states’ (...) population policy interventions. We first consider the reasons that support pro-natalist policies to enhance fertility rates and argue that these policies are ethically problematic. We then establish an ethics of population policy grounded on account of self-sustaining the body politic, which consists of four criteria: survival, replacement, accountability, and solidarity. We discuss the implications of this account regarding birth-control and pro-natalist policies, as well as non-procreative policies such as immigration, adoption, and unintended baby-saving strategies. (shrink)

Emotion-Focused Training for Emotion Coaching is based on Emotion-focused Therapy findings and was developed to help participants deepen their emotional skills. The goal was to examine the efficacy of a 12-week EFT-EC group program the level of emotion intelligence, self-compassion and self-criticism in a student population. A quasi-experiment with no control group was conducted with pre- and post-measurements using The Self-compassion scale, the Forms of Self-Criticising/attacking & Self-Reassuring Scale, and the Trait Emotional Intelligence Questionnaire – short form. The EFT-EC (...) participants were128 students. The EFT-EC intervention had a significant effect on self-criticism and self-control latent scores as reported at post-measurement. The structural equation model with latent variables was not an adequate fit for the rest of the subscales. These results are promising and suggest that interventions intended to enhance emotion skills can also reduce self-criticism even when not directly addressing it. (shrink)

Population ethics is the subfield of philosophy that focuses on the moral aspects of how actions affect who exists in a particular population and what quality of life they have. The choices regarding what policies are adopted in response to climate change will affect the identities of those who exist in the future, the size of future populations, and the quality of life that future people will have. This chapter examines the nonidentity problem, various theoretical outlooks on (...) class='Hi'>population ethics, some recent policy proposals aimed at reducing fertility, and the relationship between population reduction and the impacts of climate change. After summarizing the relevant issues, the relevance of the discourse to climate policy is highlighted, and points of consensus and dissensus are noted. Disagreement on some of the key theoretical questions in population ethics is significant and poses a challenge for deriving meaningful conclusions about climate policy. Fortunately, emerging points of consensus on other aspects of climate policy and its relationship to population provide reasons to think moral decision-making about these matters is far from hopeless. (shrink)

Every organization has to deal with operational risks, arising from the execution of a company’s primary business functions. In this paper, we describe a legal knowledge management system which helps users understand the meaning of legislative text and the relationship between norms. While much of the knowledge requires the input of legal experts, we focus in this article on NLP applications that semi-automate essential time-consuming and lower-skill tasks—classifying legal documents, identifying cross-references and legislative amendments, linking legal terms to the (...) most relevant definitions, and extracting key elements of legal provisions to facilitate clarity and advanced search options. The use of Natural Language Processing tools to semi-automate such tasks makes the proposal a realistic commercial prospect as it helps keep costs down while allowing greater coverage. (shrink)

Every organization has to deal with operational risks, arising from the execution of a company’s primary business functions. In this paper, we describe a legal knowledge management system which helps users understand the meaning of legislative text and the relationship between norms. While much of the knowledge requires the input of legal experts, we focus in this article on NLP applications that semi-automate essential time-consuming and lower-skill tasks—classifying legal documents, identifying cross-references and legislative amendments, linking legal terms to the (...) most relevant definitions, and extracting key elements of legal provisions to facilitate clarity and advanced search options. The use of Natural Language Processing tools to semi-automate such tasks makes the proposal a realistic commercial prospect as it helps keep costs down while allowing greater coverage. (shrink)

I have attempted to clarify some of the pathways in the development of Darwin's thinking. The foregoing examples of influence by no means include all that can be found by comparing Darwin's writings with Humboldt's. However, the above examples seem adequate to show the nature and extent of this influence. It now seems clear that Humboldt not only, as had been previously known, inspired Darwin to make a voyage of exploration, but also provided him with his basic orientation concerning how (...) and what to observe and how to write about it. An important part of what Darwin assimilated from Humboldt was an appreciation of population analysis as a tool for assessing the state of societies and of the benefits and hardships which these societies can expect to receive from the living world around them.Darwin exhibited in his Journal of Researches a casual interest in the economic and political conditions of the countries he visited, but these considerations were much less important to him than to Humboldt. Instead, Darwin, with the assistance of Lyell's Principles of Geology, shifted from Humboldt's largely economic framework to a biological one built around the species question. This shift led Darwin away from a consideration of how the population biology of animals was related to man's economy to focus instead upon how population biology fitted into the economy of nature.Humboldt's Personal Narrative served very well as a model for Darwin's Journal of Researches, thereby helping Darwin gain scientific eminence. The Journal of Researches, like virtually all of Humboldt's writings, was a contribution to scientific orthodoxy. But Darwin had, along the way, acquired an urge to do more than just add his building blocks to the orthodox scientific edifice. He decided to rearrange those blocks of knowledge into a different structure, and for that task neither Humboldt's Personal Narrative nor any other of his works could serve as a model. Humboldt had lacked the confidence which Darwin needed that biogeography and the origin of species could be understood. Humboldt had not explored very far the possible connections between biology and geology. Nor had he provided a general synthetic account of population biology. Had he done so, he might have been more explicit about the extent of his endorsement of Malthus. But even if he had, Humboldt's strong orientation toward cooperation would probably have inhibited his recognition of the importance of competition in nature.Lyell, who had also benefited from reading Humboldt, gave Darwin insights that were lacking in Humboldt's Personal Narrative. Lyell admirably demonstrated how stratigraphy, paleontology, biogeography, and population biology could be interrelated, and his reasons for doing so were essentially the same as Darwin's. Lyell's understanding of biogeography and ecology came from the writings of Augustin-Pyramus de Candolle as much as from Humboldt's, and from the former Lyell derived an appreciation for the importance of competition and also a confidence that the mysteries of biogeography could be explained.117 Furthermore, Lyell's discussion of all these subjects and also of evolution in his Principles of Geology is a good synthetic argument that was the ideal model for Darwin's greatest book.Darwin, having become convinced that species change through time, was able to synthesize in his mind the contributions which he had derived from the writings of Humboldt and Lyell as they applied to the species question. When Darwin wrote his Journal of Researches there were two large gaps in his thinking about evolution that bothered him—the mechanism of evolution and the causes of extinction. It was only after reading Malthus in 1838 that he realized, as Lyell had more or less pointed out, how important was competition in nature. He now had the general outlines for his theory, and in the 1845 abridged edition of his Journal, now retitled The Voyage of the Beagle, he inserted a fuller discussion of competition in nature which showed his awareness of its importance as an ecological factor.118. (shrink)

This article describes how empirical discoveries in the 1930s–1950s regarding population variation for chromosomal inversions affected Theodosius Dobzhansky and Richard Goldschmidt. A significant fraction of the empirical work I discuss was done by Dobzhansky and his coworkers; Goldschmidt was an astute interpreter, with strong and unusual commitments. I argue that both belong to a mechanistic tradition in genetics, concerned with the effects of chromosomal organization and systems on the inheritance patterns of species. Their different trajectories illustrate how scientists’ commitments (...) affect how they interpret new evidence and adjust to it. Dobzhansky was moved to revised views about selection, while Goldschmidt moved his attention to different genetic phenomena. However different, there are significant connections between the two that enrich our understanding of their views. I focus on two: the role of developmental considerations in Dobzhansky’s thought and the role of neutrality and drift in Goldschmidt’s evolutionary account. Dobzhansky’s struggle with chromosomal variation is not solely about competing schools of thought within the selectionist camp, as insightfully articulated by John Beatty, but also a story of competition between selectionist thinking and developmental perspectives. In contraposition, Goldschmidt emphasized the role of low penetrance mutations that spread neutrally and pointed out that drift could result from developmental canalization. This account adds to the dominant story about Goldschmidt’s resistance to the splitting of development from genetics, as told by Garland Allen and Michael Dietrich. The story I tell illustrates how developmental thinking and genetic thinking conflicted and influenced researchers with different convictions about the significance of chromosomal organization. (shrink)