Recent studies suggest that insects use pattern recognition molecules to distinguish prokaryotic pathogens and fungi from “self” structures. Less understood is how the innate immune system of insects recognizes endoparasitic Hymenoptera and other eukaryotic invaders as foreign. Here we discuss candidate recognition factors and the strategies used by parasitoids to overcome host defense responses. We suggest that host–parasitoid systems are important experimental models for studying how the innate immune system of insects recognizes foreign invaders that are phylogenetically more closely related (...) to their hosts. The strategies used by parasitoids suggest that insects may employ “hidden-self” recognition molecules for attacking foreign objects intruding the open circulatory system. BioEssays 23:344–351, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

This paper serves as an introduction to the special section on Global Culture Revisited which commemorates the 30th anniversary of the publication of the 1990 Global Culture special issue. It examines the development of interest in the various strands of globalization and the question of whether there can be a global culture. The paper discusses the emergence of alternative global histories and the problematization of global knowledge. It examines the view that the current Covid-19 pandemic signals a turning point, or (...) change of epoch, that marks the end of peak globalization. The paper also discusses the view that global was always a limited cartographic term which failed to adequately grasp our terrestrial location on the earth. Currently, there is considerable speculation about the emergent politics of a new world order, with civilizational states set alongside nation-states, opening up an epoch of greater pluriversality, and at the same time greater uncertainty. (shrink)

In this book, Mike W. Martin interprets Schweitzer's 'reverence for life' as an umbrella virtue, drawing together the specific virtues--authenticity, love, compassion, gratitude, justice and peace loving--in individual chapters. Martin's treatment of his subject is sympathetic yet critical, and for the first time clearly places Schweitzer's environmental ethics within the wider framework of his ethical theory.

From the inception of philosophical counseling an attempt was made to distinguish it from (psychological) therapy by insisting that therapy could not be more misleading. It is true that philosophical counselors should not pretend to be able to heal major mental illness; nevertheless they do contribute to positive health—health understood as something more than the absence of mental disease. This thesis is developed by critiquing Lou Marinoff’s book, Plato not Prozac!, but also by ranging more widely in the literature on (...) philosophical counseling. I also interpret philosophical counseling as a form of philosophical ethics. (shrink)

Yuval Noah Harari contends that human rights are an outdated myth. He calls for replacing them with a new global ethic to meet crises as varied as environmental destruction, disruptive technologies, and extreme gaps between rich and poor. Toward that end, he outlines an ethics that exalts compassion and elides justice, an ethics that animates his trilogy: Sapiens, Homo Deus, and 21 Lessons for the 21st Century. I draw together the key elements in his personal ethics, tracing them to a (...) combination of scientism, postmodernism, and Buddhism. I then argue that he misunderstands human rights, inflates the role of science in moral matters, and fails to reconcile his moral passion with his moral skepticism. (shrink)

'The Probabilistic Mind' is a follow-up to the influential and highly cited 'Rational Models of Cognition'. It brings together developments in understanding how, and how far, high-level cognitive processes can be understood in rational terms, and particularly using probabilistic Bayesian methods.

Legally defining “death” in terms of brain death unacceptably obscures a value judgment that not all reasonable people would accept. This is disingenuous, and it results in serious moral flaws in the medical practices surrounding organ donation. Public policy that relies on the whole-brain concept of death is therefore morally flawed and in need of revision.

Using a unique data set of causal usage drawn from research articles published between 2006–2008 in the American Journal of Sociology and American Sociological Review, this article offers an empirical assessment of causality in American sociology. Testing various aspects of what we consider the conventional wisdom on causality in the discipline, we find that “variablistic” or “covering law” models are not the dominant way of making causal claims, research methods affect but do not determine causal usage, and the use of (...) explicit causal language and the concept of “mechanisms” to make causal claims is limited. Instead, we find that metaphors and metaphoric reasoning are fundamental for causal claims-making in the discipline. On this basis, we define three dominant causal types used in sociology today, which we label the Probabilistic, Initiating and Conditioning types. We theorize this outcome as demonstrating the primary role that cognitive models play in providing inference-rich metaphors that allow sociologists to map causal relationships on to empirical processes. (shrink)

This white paper outlines the plans of the History Philosophy Culture Working Group of the Next Generation Event Horizon Telescope Collaboration.

There is currently a strong focus on responsible research in relation to the development of nanoscience and nanotechnology. This study presents a series of conversations with nanoresearchers, with the ‘European Commission recommendation on a code of conduct for responsible nanosciences and nanotechnologies research’ (EC-CoC) as its point of departure. Six types of reactions to the document are developed, illustrating the diversity existing within the scientific community in responses towards this kind of new approaches to governance. Three broad notions of responsible (...) nanoresearch are presented. The article concludes by arguing that while the suggestion put forward in the EC-CoC brings the concept of responsible nanoresearch a long way, one crucial element is to be wanted, namely responsible nanoresearch as increased awareness of moral choices. (shrink)

Based on metatheoretical considerations, this article discusses what kinds of traffic forecasts are possible and what kinds are impossible to make with any reasonable degree of accuracy. It will be argued on ontological and epistemological grounds that it is inherently impossible to make exact predictions about the magnitude of the ‘general’ traffic growth 20-30 years ahead, since many of the influencing factors depend on inherently unpredictable geopolitical trajectories as well as contested political decision-making. Due to the context-dependency of each particular (...) planning situation, it is also hardly possible to make exact, quantitative predictions about the impact of implementing a specific infrastructure project, compared to ‘doing nothing’. Instead of relying on traffic model simulations as the general forecasting and assessment tool in transport planning, we propose to separate the so-called strategic, tactical and operational levels of traffic forecasting into three distinct methodological approaches reflecting the different degrees of openness/closure of the systems at hand: scenario analyses at the strategic level; theory-informed, mainly qualitative analyses supplemented with simple calculations at the tactical level; while more traditional micro-simulations should be applied only at a detailed operational level. (shrink)

This paper presents new results from a detailed study of the structure of autocatalytic sets. We show how autocatalytic sets can be decomposed into smaller autocatalytic subsets, and how these subsets can be identified and classified. We then argue how this has important consequences for the evolvability, enablement, and emergence of autocatalytic sets. We end with some speculation on how all this might lead to a generalized theory of autocatalytic sets, which could possibly be applied to entire ecologies or even (...) economies. (shrink)

We begin by considering two principles, each having the form causal completeness ergo screening-off. The first concerns a common cause of two or more effects; the second describes an intermediate link in a causal chain. They are logically independent of each other, each is independent of Reichenbach's principle of the common cause, and each is a consequence of the causal Markov condition. Simple examples show that causal incompleteness means that screening-off may fail to obtain. We derive a stronger result: in (...) a rather general setting, if the composite cause C1 & C2 & … & Cn screens-off one event from another, then each of the n component causes C1, C2, …, Cn must fail to screen-off. The idea that a cause may be ordinally invariant in its impact on different effects is defined; it plays an important role in establishing this no-go theorem. Along the way, we describe how composite and component causes can all screen-off when ordinal invariance fails. We argue that this theorem is relevant to assessing the plausibility of the two screening-off principles. The discovery of incomplete causes that screen-off is not evidence that causal completeness must engender screening-off. Formal and epistemic analogies between screening-off and determinism are discussed. (shrink)

Nanoscale objects are presented by ever more sophisticated pictures. There is a need to reflect on the status of such nano images, because the “seeing” involved is of a highly indirect kind. The aim of this paper is to complement existing philosophical critique of nano images with a scientific practitioner's perspective. First, we show some reasons to consider seeing and imaging as complex endeavours not only on the micro and nano scale, but also on the macro level. Secondly, we argue (...) that practising scientists are not only accustomed to interpret pictures and other graphical presentations of data as being partial and simplified, but that simplification is deliberate and internal. Rather than requiring that “true” images have to be representational, the paper advocates for the fruitfulness of understanding and judging images by the amount and nature of the information they convey. Scientific literacy could be improved by creative development of visualization techniques, but also by improved public understanding of images and their correct and cautious interpretation. (shrink)

Brent Kious has recently attacked several arguments generally adduced to support anti-doping in sports, which are widely supported by the sports medicine fraternity, international sports federations, and international governments. We show that his attack does not succeed for a variety of reasons. First, it uses an overly inclusive definition of doping at odds with the WADA definition, which has global, if somewhat contentious, currency. Second, it seriously misconstrues the position it attacks, rendering the attack without force against a more balanced (...) construal of an anti-doping position. Third, it makes unwarranted appeals to matters Kious considers morally ‘clear’, while simultaneously attacking a position many others take to be equally morally ‘clear’, namely that of anti-doping. Such an inconsistency, attacking and appealing to the moral status quo as befits one’s argument, is not acceptable without further qualification. Fourth, his position suffers from a general methodological flaw of over-reliance upon argumentation by analogy. Moreover, it is argued that the analogies, being poorly selected and developed, fail to justify his conclusion that the anti-doping lobby lacks philosophical and moral authority for its stance. These issues are symptomatic of a more fundamental problem: any attempt at providing a blanket solution to the question of whether doping is morally acceptable or not is bound to run up against problems when applied to highly specific contexts. Thus, rather than reaching any particular conclusion for or against doping products or processes in this article, we conclude that an increased context-sensitivity will result in a more evenhanded appraisal of arguments on the matter. (shrink)

Interest in postmodernity has stagnated over the past decade and has come to be partially replaced by a concern with globalization. While the two terms are often considered to be divergent there is continuity as theoretical discourse transfers from one to the other. In what follows, we first distill the heuristic models employed by various knowledge-geographical traditions of social thought in conceptualizing postmodernism. We then transpose these models into recent debates on globalization. Globalization theory has become the provenance of British (...) and American theorists because of a contiguity that extends back to a propitious model employed to understand postmodernism. Globalization theory in France and Germany are largely non-existent or tangential for similar reasons that find opposite tendencies. The spatial and temporal aspect inherent to both the modern and postmodern indicates that both already present a stance on globalization. Among the key factors predicting the fortunes of heuristic models is the continuation of classical theoretical concerns in the present situation of globalization. Post-classical tendencies in heuristic models indicate that more cloistered postmodern concerns do not transfer well to globalization. Those heuristic models that conceive of a postmodernist break are those whose application to present instantiations of globalization is subsequently limited. (shrink)

In a recent commentary, Kim and colleagues argued that minimal-risk research should be deregulated so that such studies do not require review by an institutional review board. They claim that regulation of minimal-risk studies provides no adequate counterbalancing good and instead leads to a costly human subjects oversight system. We argue that the counterbalancing good of regulating minimal-risk studies is that oversight exists to ensure that respect for persons and justice requirements are satisfied when they otherwise might not be.

In the formation of the multi-disciplinary field that investigates the participation of disabled persons in all forms of physical activity, little ethical and philosophical work has been published. This essay serves to contextualise a range of issues emanating from adapted physical activity (APA) and disability sports. First, we offer some general historical and philosophical remarks about the field which serve to situate those issues at the crossroads between the philosophy of disability and the philosophy of sports. Secondly, we bring brief (...) but critical attention to the contestation of key concepts such as ?ability? and ?normality? and the recent criticisms of polarisation of the medical and social models of disability. Finally, we show how these conceptual issues are implicated in the whole spectrum of contexts of APA and disability sports from the ethics of research with and for the disabled, to coaching, rehabilitation and teaching, and sports administration, that are predicated on key ethical concepts including empathy, entitlement and equity. (shrink)

Brent Kious has objected to our previous criticism of his views on doping, maintaining that we, by and large, misrepresented his position. In this response, we strengthen our original misgivings, arguing that (1) his views on risk of harm in sport are either uncontroversially true (not inconsistent with the views of many doping opponents) or demonstrably false (attribute to doping opponents an overly simplistic view), (2) his use of analogies (still) indicates an oversimplification of many issues surrounding the question of (...) doping in sports, and (3) his doping analogies are insufficiently precise to support his conclusions. (shrink)

In this paper, we examine how SMEs successfully implement proactive social and environmental strategies (PSEs). Using inductive theory building on 8 case studies of small and medium enterprises (SMEs) operating in both developing and developed country contexts, we identify four dynamic capabilities that explain how SMEs overcome time, resources, knowledge, and power constraints when implementing proactive social and environmental strategies. We introduce three moderating variables to explain how level of country development, organizational lifecycle, and availability of supporting institutions could impact (...) the level of capability importance. Furthermore, we discuss the interconnectedness of these capabilities to fully explore their dynamism in explaining how SMEs engage in sustainable business practices. (shrink)

In the model theory of modules the Ziegler spectrum, the space of indecomposable pure-injective modules, has played a key role. We investigate the possibility of defining a similar space in the context of G-sets where G is a group.

How can a critical analysis of entrepreneurial intention inform an appreciation of ethics in social enterprise business models? In answering this question, we consider the ethical commitments that inform entrepreneurial action and the hybrid organisations that emerge out of these commitments and actions. Ethical theory can be a useful way to reorient the field of social enterprise so that it is more critical of bureaucratic and market-driven enterprises connected to neoliberal doctrine. Social enterprise hybrid business models are therefore reframed as (...) outcomes of both ethical and entrepreneurial intentions. We challenge the dominant conceptualisation of social enterprise as a hybrid blend of mission and market by reframing hybridity in terms of the moral choice of economic system and social value orientation. We deconstruct the political foundations of charitable trading activities, co-operative and mutual enterprises and socially responsible businesses by examining the rationalities and ethical commitments that underpin them. Whilst conceptual modelling of social enterprise is not new, this paper contributes to knowledge by developing a theory of social enterprise ethics based on the moral/political choices that are made by entrepreneurs when choosing between systems of economic exchange and social value orientation, then expressing it through a legal form. (shrink)

In response to calls for greater interdisciplinary involvement from the social sciences and humanities in the development, governance, and study of artificial intelligence systems, this paper presents one sociologist’s view on the problem of algorithmic bias and the reproduction of societal bias. Discussions of bias in AI cover much of the same conceptual terrain that sociologists studying inequality have long understood using more specific terms and theories. Concerns over reproducing societal bias should be informed by an understanding of the ways (...) that inequality is continually reproduced in society—processes that AI systems are either complicit in, or can be designed to disrupt and counter. The contrast presented here is between conservative and radical approaches to AI, with conservatism referring to dominant tendencies that reproduce and strengthen the status quo, while radical approaches work to disrupt systemic forms of inequality. The limitations of a conservative approach to racial bias are discussed through the specific example of biased criminal risk assessments and Indigenous overrepresentation in Canada’s criminal justice system. This illustrates the dangers of treating racial bias as a generalizable problem and equality as a generalizable solution, emphasizing the importance of considering inequality in context. Societal issues can no longer be out of scope for AI and machine learning, given the impact of these systems on human lives. This requires engagement with a growing body of critical AI scholarship that goes beyond biased data to analyze structured ways of perpetuating inequality, opening up the possibility for interdisciplinary engagement and radical alternatives. (shrink)

This article is concerned with the relationship between body, image and affect within consumer culture. Body image is generally understood as a mental image of the body as it appears to others. It is often assumed in consumer culture that people attend to their body image in an instrumental manner, as status and social acceptability depend on how a person looks. This view is based on popular physiognomic assumptions that the body, especially the face, is a reflection of the self: (...) that a person’s inner character or personality will shine through the outer appearance. The modification and cosmetic enhancement of the body through a range of regimes and technologies can be used to construct a beautiful appearance and thereby a beautiful self. The article begins by examining body images in consumer culture and their relation to photography and moving images. This is followed by an examination of the consumer culture transformative process through a discussion of cosmetic surgery. The article then questions the over-simplistic logic that assumes that transformative techniques will automatically result in a more positive and acceptable body image. The new body and face may encourage people to look at the transformed person in a new way. But the moving body, the body without image, which communicates through proprioceptive senses and intensities of affect, can override the perception of the transformed appearance. A discussion of the affective body follows, via a closer examination of the body without image, the opening of the body to greater affect and indeterminacy. The affective body image and its potential greater visibility through new media technologies are then discussed through some examples taken from digital video art. The article concludes by examining some of the implications of these shifts within consumer culture and new media technologies. (shrink)

Are people rational? This question was central to Greek thought and has been at the heart of psychology and philosophy for millennia. This book provides a radical and controversial reappraisal of conventional wisdom in the psychology of reasoning, proposing that the Western conception of the mind as a logical system is flawed at the very outset. It argues that cognition should be understood in terms of probability theory, the calculus of uncertain reasoning, rather than in terms of logic, the calculus (...) of certain reasoning. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:What Now?Mike AbellThe cry broke the church’s uncomfortable silence. It actually was more of a moan than a cry. It was deeper, coming from her core. I’d heard it only once before and knew it as a sound caused by a loss that will never be recovered. No one in the church had to turn to discover its source. We all knew the mother had entered to say (...) goodbye to her 19–month–old son.We watched as the now composed mother, along side her husband, followed the small casket—a family rendered incomplete. As they passed our pew, my wife clutched my arm and we wept tears of sympathy, guilt and fear.Just 15 months earlier our now, 2–and ½–year–old son, Jun, had been diagnosed with a brain tumor not dissimilar from the child in the casket. The tumor has a different name, but it’s equally complicated, and comparably rare and aggressive.Over nine months, Jun endured two craniotomies, three rounds of induction chemo, three rounds of high dose chemo with stem cell rescue, 28 days of proton radiation, a sub–dural shunt placement, a port placed and removed, a broviac placed and removed and many, many blood and [End Page 16] platelet transfusions. As of his last scan, there was no evidence of tumor.Jun has now been out of treatment for six months. His hair has grown back. He’s stronger. The meals have stopped arriving. And we no longer are the recipients of sad eyes at playgrounds and restaurants.In many ways we have returned to a somewhat normal life. If you didn’t know Jun was in remission for a brain tumor, you wouldn’t know. Despite all this, cancer still strangles us with fear.Brain tumors often come back. Too often. We’ve heard a few different numbers on the likelihood. And while we’ve never paid too much attention to statistics, they are too scary to ignore. Especially knowing that should it recur, there is no cure. This is our day–to–day reality.A lot of our time is spent analyzing, over analyzing and obsessing. We watch him closely. Every time he stumbles, coughs, or sleeps fifteen minutes longer than normal, we wonder if it’s something more. I’ve called our oncologist about a 99–degree temperature. Something I wouldn’t have done during treatment (I usually waited to 100). I’ve questioned whether hiccups are a sign of recurrence. Admittedly, I’ve even Googled that last one just to be sure.All the anxiety builds the closer you get to an MRI date. My son has scans every three months so I’m beginning to recognize the cycle. It starts a couple weeks out. Normally it begins as a twinge the moment the date is set. But each day it grows, occupying more and more of my mind. This is not to say, I don’t think about it everyday. I do. But the thoughts become more paranoid and frequent. Worst–case scenarios play out. It’s different from the time during treatment. We always had the comfort of knowing that there is still more treatment.By the time we reach MRI day, bring Jun back to the machine room, watch the anesthesiologist put him under, and leave him to be scanned for the next two and half hours, I feel close to nauseas. In my mind, at this point, someone knows. I know they may be a technician and are not necessarily trained to read an MRI. But they know. They’ve seen it before.There usually is a waiting period between the time of the scan and the time you can meet with your oncologist or someone else qualified to read and interpret the scan. I do whatever I can to make that window as narrow as possible. I leave radiology with a disc in hand and head directly to the clinic to pass it off. I’ve heard of people waiting days for an appointment. That’s not an option for me. There would be no eating, no sleeping, and no resting heart rate without knowing. Fortunately, our oncologist is... (shrink)

Part of understanding the meaning and power of algorithms means asking what new demands they might make of ethical frameworks, and how they might be held accountable to ethical standards. I develop a definition of networked information algorithms as assemblages of institutionally situated code, practices, and norms with the power to create, sustain, and signify relationships among people and data through minimally observable, semiautonomous action. Starting from Merrill’s prompt to see ethics as the study of “what we ought to do,” (...) I examine ethical dimensions of contemporary NIAs. Specifically, in an effort to sketch an empirically grounded, pragmatic ethics of algorithms, I trace an algorithmic assemblage’s power to convene constituents, suggest actions based on perceived similarity and probability, and govern the timing and timeframes of ethical action. (shrink)

Mike Murray's excellent new book attacks the narrow high stakes accountability and marketized vision which has distorted our education system and offers a radical optimistic vision of how we can emerge from the current impasse.

There are few, if any, aspects of contemporary sport that do not raise ethical questions. From on-field relationships between athletes, coaches and officials, to the corporate responsibility of international sports organizations and businesses, ethical considerations permeate sport at every level. This important new collection of articles showcases the very best international scholarship in the field of sports ethics, and offers a comprehensive, one-stop resource for any student, scholar or sportsperson with an interest in this important area. It addresses cutting-edge contemporary (...) themes within sports ethics, such as gene doping, as well as introducing classic ethical debates that define our understanding of sport, sporting conduct and sport in practice. _The Ethics of Sports_ is arranged into seven thematic sections, each of which includes an introduction by the editor that highlights the key themes and places each article in context, and offers suggestions for further reading. _The Ethics of Sports _sheds new light on a wide range of issues within contemporary sports studies including doping, disability, gender and ethnicity; the practice of physical education and sports coaching; sports media; sports business and sports medicine. It is essential reading for all students with an interest in sport or applied ethics. (shrink)

The paper aims to show that, if S5 is the logic of metaphysical necessity, then no state of affairs in any possible world constitutes any non-trivial evidence for or against the existence of the traditional God. There might well be states of affairs in some worlds describing extraordinary goods and extraordinary evils, but it is false that these states of affairs constitute any (non-trivial) evidence for or against the existence of God. The epistemological and metaphysical consequences for philosophical theology of (...) assuming that S4 or Kσρ is the logic of metaphysical necessity are equally untenable. S4 guarantees that God does not exist if there is the slightest evidence against the existence of God. And Kσρ guarantees that God might survive the loss or acquisition of any essential property at all. (shrink)

This book explores a new approach to understanding the human mind - rational analysis - that regards thinking as a facility adapted to the structure of the world. This approach is most closely associated with the work of John R Anderson, who published the original book on rational analysis in 1990. Since then, a great deal of work has been carried out in a number of laboratories around the world, and the aim of this book is to bring this work (...) together for the benefit of the general psychological audience. The book contains chapters by some of the world's leading researchers in memory, categorisation, reasoning, and search, who show how the power of rational analysis can be applied to the central question of how humans think. It will be of interest to students and researchers in cognitive psychology, cognitive science, and animal behaviour. (shrink)

This paper addresses the apparent mismatch between the normative and descriptive literatures in the cognitive science of conditional reasoning. Descriptive psychological theories still regard material implication as the normative theory of the conditional. However, over the last 20 years in the philosophy of language and logic the idea that material implication can account for everyday indicative conditionals has been subject to severe criticism. The majority view is now apparently in favour of a subjective conditional probability interpretation. A comparative model fitting (...) exercise is presented that shows that a conditional probability model can explain as much of the data on abstract indicative conditional reasoning tasks as psychological theories that supplement material implication with various rationally unjustified processing assumptions. Consequently, when people are asked to solve laboratory reasoning tasks, they can be seen as simply generalising their everyday probabilistic reasoning strategies to this novel context. (shrink)