Phillips argues that blindsight is due to response criterion artefacts under degraded conscious vision. His view provides alternative explanations for some studies, but may not work well when one considers several key findings in conjunction. Empirically, not all criterion effects are decidedly non-perceptual. Awareness is not completely abolished for some stimuli, in some patients. But in other cases, it was clearly impaired relative to the corresponding visual sensitivity. This relative dissociation is what makes blindsight so important and interesting.

The grounds of justice -- "Un pouvoir ordinaire": shared membership in a state as a ground of -- Justice -- Internationalism versus statism and globalism: contemporary debates -- What follows from our common humanity? : the institutional stance, human rights, and nonrelationism -- Hugo Grotius revisited : collective ownership of the Earth and global public reason -- "Our sole habitation" : a contemporary approach to collective ownership of the earth -- Toward a contingent derivation of human rights -- Proportionate use (...) : immigration and original ownership of the Earth -- "But the earth abideth for ever" : obligations to future generations -- Climate change and ownership of the atmosphere -- Human rights as membership rights in the global order -- Arguing for human rights : essential pharmaceuticals -- Arguing for human rights : labor rights as human rights -- Justice and trade -- The way we live now -- "Imagine there's no countries" : a reply to John Lennon -- Justice and accountability : the state -- Justice and accountability : the World Trade Organization. (shrink)

Priority setting in health care is ubiquitous and health authorities are increasingly recognising the need for priority setting guidelines to ensure efficient, fair, and equitable resource allocation. While cost-effectiveness concerns seem to dominate many policies, the tension between utilitarian and deontological concerns is salient to many, and various severity criteria appear to fill this gap. Severity, then, must be subjected to rigorous ethical and philosophical analysis. Here we first give a brief history of the path to today’s severity criteria in (...) Norway and Sweden. The Scandinavian perspective on severity might be conducive to the international discussion, given its long-standing use as a priority setting criterion, despite having reached rather different conclusions so far. We then argue that severity can be viewed as a multidimensional concept, drawing on accounts of need, urgency, fairness, duty to save lives, and human dignity. Such concerns will often be relative to local mores, and the weighting placed on the various dimensions cannot be expected to be fixed. Thirdly, we present what we think are the most pertinent questions to answer about severity in order to facilitate decision making in the coming years of increased scarcity, and to further the understanding of underlying assumptions and values that go into these decisions. We conclude that severity is poorly understood, and that the topic needs substantial further inquiry; thus we hope this article may set a challenging and important research agenda. (shrink)

The associative theory of creativity states that creativity is associated with differences in the structure of semantic memory, whereas the executive theory of creativity emphasises the role of top-down control for creative thought. For a powerful test of these accounts, individual semantic memory structure was modelled with a novel method based on semantic relatedness judgements and different criteria for network filtering were compared. The executive account was supported by a correlation between creative ability and broad retrieval ability. The associative account (...) was independently supported, when network filtering was based on a relatedness threshold, but not when it was based on a fixed edge number or on the analysis of weighted networks. In the former case, creative ability was associated with shorter average path lengths and higher clustering of the network, suggesting that the semantic networks of creative people show higher small-worldness. (shrink)

This article highlights the continuing relevance of a classic bioethical text, “Bioethics as a Discipline,” published by the Hastings Center’s cofounder Daniel Callahan in 1973. Connecting the text’s programmatic recommendations with later reflections and interventions Callahan wrote about the development of bioethics illuminates how the vision Callahan established and the reality this vision helped create were interrelated—just not in the way Callahan had hoped for. Although this portrait relies on an individual perception of the development of bioethics, it might nevertheless, (...) through its unique linkage of different bioethical temporalities, contribute to a broader reassessment of what bioethics became and why. (shrink)

In a recent extended essay, philosopher Daniel Hausman goes a long way towards dismissing severity as a morally relevant attribute in the context of priority setting in healthcare. In this response, we argue that although Hausman certainly points to real problems with how severity is often interpreted and operationalised within the priority setting context, the conclusion that severity does not contain plausible ethical content is too hasty. Rather than abandonment, our proposal is to take severity seriously by carefully mapping the (...) possibly multiple underlying accounts to well-established ethical theories, in a way that is both morally defensible and aligned with the term’s colloquial uses. (shrink)

von Lothar Brock Wer dieses Buch zur Hand nimmt, sollte sich einen Autor vorstellen, der einer Gruppe hartgesottener Geschäftsleute aus der Wüste von New Mexico morgens um sieben mit charmanter Leichtigkeit und spärlichen, aber Verbindung stiftenden Gesten einen Vortrag über die EU als einer vorgestellten Gemeinschaft hält und dafür überschwenglich gefeiert wird. Oder einen Theoretiker mit verblüffend praktischen Kenntnissen über Höhenmedizin und der unter bestimmten Umständen lebensrettenden Fähigkeit, panischen Berggefährten den Anblick der Tiefe erträglich zu machen. Oder den lead-Sänger einer (...) ziemlich professionellen Musikgruppe, die sich die öffentliche Pflege des Liedgutes der Rolling Stones zur Aufgabe gemacht hat und als Meister der Reproduktion die Bewunderer des Originals in Taumel versetzt - von Stockholm bis OfIenbach. Auf keinen Fall aber sollte man sich einen Autor vorstellen wie man ihn sich vorstellt, wenn man dieses Buch zur Hand nimmt. Oder doch? Doch! Es könnte ja sein, daß jemand dieses Buch nicht nur als lohnende Strapaze erlebt, sondern auch als Vergnügen, wenn er erst einmal über den Untertitel hinweggekommen ist. Zur Sache:,,Fallen der Welt-Ordnung" - die Fallen oder das Fallen? Das Thema verrät es nicht; denn zwischen Moderne und Postmoderne ist ein weites Feld, auf dem alles mögliche passieren kann. Worum also geht es? Mathias Albert versteht das Arbeitsgebiet der Internationalen Beziehungen (also der Lehre und Forschung über diesen Gegenstandsbereich) als jenen Teilbereich der Sozialwissenschaften, der sich mit der Weltordnung befaßt. (shrink)

Poly(ADP‐ribosyl)ation is a post‐translational modification occurring in the nucleus. The most abundant and best‐characterized enzyme catalyzing this reaction, poly(ADP‐ribose) polymerase 1 (PARP1), participates in fundamental nuclear events. The enzyme functions as molecular “nick sensor”. It binds with high affinity to DNA single‐strand breaks resulting in the initiation of its catalytic activity. Activated PARP1 promotes base excision repair. In addition, PARP1 modifies several transcription factors and thereby precludes their binding to DNA. We propose that a major function of PARP1 includes the (...) silencing of transcription preventing expression of damaged genes. Concomitant stimulation of DNA repair suggests that PARP1 acts as a switch between transcription and DNA repair. Another PARP‐type enzyme, tankyrase, is involved in the regulation of telomere elongation. Tankyrase modifies a telomere‐associated protein and thereby prevents it masking telomeric repeats providing access of telomerase for telomere elongation. Therefore, poly(ADP‐ribosyl)ation reactions may act as molecular switches in DNA metabolism. BioEssays 23:543–548, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

This essay reconstructs the place of utopia in realist political theory, by examining the ways in which the literary genre of critical utopias can productively unsettle ongoing discussions about “how to do political theory.” I start by analyzing two prominent accounts of the relationship between realism and utopia: “real utopia” and “dystopic liberalism”. Elaborating on Raymond Geuss’s recent reflections, the essay then claims that an engagement with literature can shift the focus of these accounts. Utopian fiction, I maintain, is useful (...) for comprehending what is and for contemplating what might be. Ursula K. Le Guin’s novel The Dispossessed deploys this double function in an exemplary fashion: through her dynamic and open-ended portrayal of an Anarchist community, Le Guin succeeds in imagining a utopia that negates the status quo, without striving to construct a perfect society. The book’s radical, yet ambiguous, narrative hence reveals a strategy for locating utopia within realist political theory that moves beyond the positions dominating the current debate. Reading The Dispossessed ultimately demonstrates that realism without utopia is status quo–affirming, while utopia without realism is wishful thinking. (shrink)

This chapter examines the role of parameterParametercalibrationCalibration in the confirmation and validation of complex computer simulation models. I examine the question to what extent calibration data can confirm or validate the calibrated model, focusing in particular on Bayesian approaches to confirmation. I distinguish several different Bayesian approaches to confirmation and argue that complex simulation models exhibit a predictivist effect: Complex computer simulation models constitute a case in which predictive success, as opposed to the mere accommodation of evidence, provides a more (...) stringent test of the model. DataData used in tuning do not validate or confirm a model to the same extent as data successfully predicted by the model do. (shrink)

The idea that morality and prudence are incommensurable normative domains—a central idea in normative pluralism—tends to be rejected because of the argument from nominal–notable comparisons. The argument relies on a premise that there are situations of moral–prudential conflict where we have a clear intuition that there are things we ought to do “all things considered”. It is usually concluded that this shows that morality and prudence must be comparable. I argue that normative pluralists, who defend this type of incommensurability, can (...) account for these intuitions by arguing that an “ought all things considered” need not presuppose inter-type comparability among the reasons it covers, and by endorsing more sophisticated theories of prudence; theories for which there are good, independent reasons to endorse, in any case. By following these steps, normative pluralism does not need to have the counterintuitive implications it is often thought to have. (shrink)

Der Philosoph Johann Gottlieb Fichte (1762–1814) gilt mit seiner sogenannten ›Wissenschaftslehre‹ als einer der bedeutendsten Vertreter einer transzendentalen Theorie über – modern gesprochen – Wissenschaftstheorie. Könnten so seine Entdeckungen nicht auch für die Theologie systematische Bedeutung haben, insbesondere in der Frage, ob diese selber eine Wissenschaft sein kann? Mathias Müller versucht anhand einer systematischen Konstruktionsanalyse von Fichtes Schrift »Die Principien der Gottes- Sitten- u. Rechtslehre. Februar und März 1805« zu zeigen, dass und wie in der Wissenschaftslehre diese selber eine (...) Grundlegung bildet, die als eine Grundlagentheorie der Theologie eingesehen werden kann. Mittels des Modells des ›Transzensus‹ wird versucht, einen für das transzendentale Ich gangbaren Weg nachzuzeichnen und anzubieten, um so – performativ erlebbar – die Wissenschaftlichkeit einer Theologie als transzendentale Fundamentaltheologie zu erschliessen. (shrink)

ABSTRACTThis paper considers the moral justifiability of military conscription. Philosopher James Pattison has developed a theoretical framework for this purpose that he calls the Moderate Instrumentalist Approach, which assesses forms of military recruitment in light of a weighted comparison of three main factors: military effectiveness, democratic control and proper treatment of military personnel. According to Pattison, all-volunteer force systems are morally preferable by comparing better when it comes to these factors than other systems of military recruitment, notably conscription. However, I (...) argue that Pattison fails to evaluate certain hybrid systems, in particular what I call the Nordic Model of Conscription. I show that there are good reasons to think that such a hybrid system compares just as well or even better than an all-volunteer force, making the Nordic Model of Conscription at least as morally justifiable and arguably also morally preferable. (shrink)

In this paper we present applications of the ACGT Master Ontology (MO) which is a new terminology resource for a transnational network providing data exchange in oncology, emphasizing the integration of both clinical and molecular data. The development of a new ontology was necessary due to problems with existing biomedical ontologies in oncology. The ACGT MO is a test case for the application of best practices in ontology development. This paper provides an overview of the application of the ontology within (...) the ACGT project thus far. (shrink)

Speech planning is a sophisticated process. In dialog, it regularly starts in overlap with an incoming turn by a conversation partner. We show that planning spoken responses in overlap with incoming turns is associated with higher processing load than planning in silence. In a dialogic experiment, participants took turns with a confederate describing lists of objects. The confederate’s utterances (to which participants responded) were pre‐recorded and varied in whether they ended in a verb or an object noun and whether this (...) ending was predictable or not. We found that response planning in overlap with sentence‐final verbs evokes larger task‐evoked pupillary responses, while end predictability had no effect. This finding indicates that planning in overlap leads to higher processing load for next speakers in dialog and that next speakers do not proactively modulate the time course of their response planning based on their predictions of turn endings. The turn‐taking system exerts pressure on the language processing system by pushing speakers to plan in overlap despite the ensuing increase in processing load. (shrink)

Much has been written on the role of causal notions and causal reasoning in the so-called 'special sciences' and in common sense. But does causal reasoning also play a role in physics? Mathias Frisch argues that, contrary to what influential philosophical arguments purport to show, the answer is yes. Time-asymmetric causal structures are as integral a part of the representational toolkit of physics as a theory's dynamical equations. Frisch develops his argument partly through a critique of anti-causal arguments and (...) partly through a detailed examination of actual examples of causal notions in physics, including causal principles invoked in linear response theory and in representations of radiation phenomena. Offering a new perspective on the nature of scientific theories and causal reasoning, this book will be of interest to professional philosophers, graduate students, and anyone interested in the role of causal thinking in science. (shrink)

Mathias Frisch provides the first sustained philosophical discussion of conceptual problems in classical particle-field theories. Part of the book focuses on the problem of a satisfactory equation of motion for charged particles interacting with electromagnetic fields. As Frisch shows, the standard equation of motion results in a mathematically inconsistent theory, yet there is no fully consistent and conceptually unproblematic alternative theory. Frisch describes in detail how the search for a fundamental equation of motion is partly driven by pragmatic considerations (...) (like simplicity and mathematical tractability) that can override the aim for full consistency. The book also offers a comprehensive review and criticism of both the physical and philosophical literature on the temporal asymmetry exhibited by electromagnetic radiation fields, including Einstein's discussion of the asymmetry and Wheeler and Feynman's influential absorber theory of radiation. Frisch argues that attempts to derive the asymmetry from thermodynamic or cosmological considerations fail and proposes that we should understand the asymmetry as due to a fundamental causal constraint. The book's overarching philosophical thesis is that standard philosophical accounts that strictly identify scientific theories with a mathematical formalism and a mapping function specifying the theory's ontology are inadequate, since they permit neither inconsistent yet genuinely successful theories nor thick causal notions to be part of fundamental physics. (shrink)

In diesem Buch werden die zwei Grundsäulen der "Kritischen Patriarchatstheorie" - die Matriarchale Naturphilosophie und die Patriarchatskritische Geschichtsphilosophie - vorgestellt und im Rahmen einer kritischen Auseinandersetzung mit der Naturphilosophie Giordano Brunos sowie der Geschichtsphilosophie Martin Heideggers erläutert.

After critical appraisal of mathematical and biological characteristics of the model, we discuss how a classical hippocampal neural network expresses functions similar to those of the chaotic model, and then present an alternative stimulus-driven chaotic random recurrent neural network (RRNN) that learns patterns as well as sequences, and controls the navigation of a mobile robot.

Christians, and those of the Roman Catholic Church, have made significant adjustments to their participation in Sunday liturgy in the wake of the coronavirus disease 2019 (COVID-19) pandemic. This is especially the case for Catholic Christians at the ‘Our Lady of Loreto’ (OLL) Church in Kempton Park in South Africa. Sunday Church services that used to be compulsory for most Catholic families and community members, are now attended by few and in some cases none from staunch Catholic families and communities. (...) However, this is not a new phenomenon in the Catholic Church. It signals the extent to which the COVID-19 pandemic has altered and continues to affect Christian families and their commitment to the Sunday liturgy. Drawing from qualitative interviews conducted with eight staunch Catholic community leaders of OLL Church in Kempton Park, Johannesburg, this paper explores the motivations for their continuous participation and/or non-participation in the Sunday liturgy in the wake of the pandemic. The findings reveal that certain behavioural patterns or activities associated with the COVID-19 pandemic motivate Catholic Christians and families to continue to participate and/or not participate in the Sunday liturgy. Contribution: The article explored and examined the way in which COVID-19 has affected Catholic Christians’ ability to attend Sunday liturgy. It discovered that while some Christians returned to church after the pandemic, others have continued to worship from home because of the influence of changes adopted during the pandemic. (shrink)

The potential conflicts between morality and self-interest lie at the heart of ethics. These conflicts arise because both moral and prudential considerations apply to our choices. A widespread assumption in philosophical ethics is that by weighing moral and prudential reasons against each other, we can compare their relative weights and determine what we ought to do in the face of such conflicts. While this assumption might seem innocuous and fruitful, a closer examination suggests that it lacks both justification and the (...) necessary content that would allow it to do the normative work it promises. In this book, Mathea Slåttholm Sagdahl grapples with these cases of conflict, but argues that there may be no simple answer to the question of what we ought to do all things considered. Sagdahl argues against the assumption of comparability and defends an alternative pluralist theory of normativity where morality and prudence form two separate and incommensurable normative standpoints, much like in Henry Sidgwick's "Dualism of Practical Reason." This type of view has tended to be quickly dismissed by its opponents, but Sagdahl argues that the theory is in fact a well-motivated theory of normativity and that the typical objections that tend to target it are much weaker than they are usually thought to be. (shrink)

Volume 52, Issue 6, June - July 2020, Page 602-612.

Richard Matheson seeded several weird fish in the deep and dark waters of the American myth pool, not least as a prominent screenwriter for the legendary 1960s TV series The Twilight Zone. I Am Legend, a post-apocalyptic science fiction/horror novel, published in 1954 and set in 1976, remains one of his best known works.1 It shows up persistently on "Best of Horror" lists and is generally regarded as a milestone in modern Gothic fiction. What is it about this novel that (...) has invested it with canonical status? It tells a surpassingly bleak story, one that seems to encode very specific and largely outdated cultural anxieties. And as prophecy, it falls rather flat: Matheson depicts a vampire holocaust, and the .. (shrink)

Dans cet ouvrage, l'auteur se livre à une comparaison conceptuelle entre le principe de précaution et le principe responsabilité. Il combat la démarche tendancieuse des penseurs de la précaution qui, à l'image de Corinne Lepage, dont la conception a été reprise par le chef de l'Etat français lors du " Grenelle de l'Environnement ", assimilent précaution et responsabilité, réduisant la seconde à la première. Précaution et responsabilité ne sont en réalité absolument pas réductibles, et le principe responsabilité tel que défini (...) par Hans Jonas contient les germes d'une remise en question du mode de développement occidental, dont la notion de développement durable est actuellement le fer de lance, que le principe de précaution ne permet pas - et qu'il interdit même. Politique de Cassandre dévoile ainsi l'escroquerie politico-intellectuelle dont le principe de précaution est la manifestation, et dont le " Grenelle de l'environnement " est le dernier avatar. La responsabilité politique ne consiste à intervenir ni en aval de la catastrophe comme nous y oblige le développement techno-scientifique, ni en amont de la catastrophe et en aval des causes de cette catastrophe comme nous y incite le principe de précaution, mais en amont des causes de la catastrophe. Cet essai, à la fois philosophique, politique et poétique, tente d'allier la rigueur de la démarche intellectuelle, le souci moral de la pratique et la sensibilité humaine. (shrink)

This paper explores the nature and value of melancholy and the rationality of being in such a state. I defend a view of melancholy as a highly complex mood-like state. This complexity shows itself...

Vor dem Hintergrund der Debatte um nichtbegriffliche Vorstellungsinhalte sucht diese Arbeit ein adäquates Verständnis von Kants Lehre der Erkenntnisquellen, Sinnlichkeit und Verstand, und der Ungleichartigkeit der anschaulichen und begrifflichen Vorstellungsweise, speziell bezüglich der Transzendentalen Ästhetik, der Lehre der transzendentalen Synthesis der Einbildungskraft (Selbstaffektion) und der Theorie des transzendentalen Schematismus. -/- Engaging in the Kantian debate on the existence of non-conceptual content, this work attempts to provide an adequate understanding of Kant’s doctrine of the two sources of human knowledge, sensibility and (...) understanding, and of their heterogeneous ways of representing, through intuitions and concepts. It elaborates on a consistent reading of this dualism in relation to the Transcendental Aesthetic, the synthesis of imagination, and the schematism. (shrink)

Der Band setzt sich mit den Bedingungen und Möglichkeiten internationalen oder globalen Regierens in einer sozialen Umwelt (Weltgesellschaft) unter drei Perspektiven auseinander: der Perspektive von Theorien globaler Ordnung, der Perspektive spezifischer Formen globaler Ordnungsbildung und der Perspektive die Normativität globaler Ordnung. Die Beiträge des Bandes besetzen Schnittstellen in einer Reihe von Diskussionen, die in den Internationalen Beziehungen zu Ordnung und Ordnungsbildung in der internationalen Politik, zum Regieren jenseits des Nationalstaates, sowie zur Stellung internationaler Politik in der Weltgesellschaft geführt werden.

This book assesses the impact of the work of Chris Brown in the field of International Political Theory. The volume engages with general issues of IPT as well as basic issues such as the use and role of practical reasoning and presents a nuanced understanding about issues regarding the legitimacy of war and violence. It explores questions that pertain to human rights, morality, and ethics, and generally an outlook for devising a ‘better’ world. The project is ideal for audiences with (...) interest in International Relations, Ethics and Morality Studies and International Political Theory. (shrink)

Cet essai à teneur philosophique s'intéresse à la force d'évocation et d'invocation de la musique. à son charme magique dirait Nietzsche. Comment la musique me parle-t-elle '? Que suggère-t-elle? Pourquoi parle-t-elle de moi? Quelle fonction a-t-elle dans l'humanité '? L'argumentation de l'auteur utilise la philosophie et la psychologie musicales afin d'expliquer la scandaleuse disproportion entre la puissance à dire de la musique et l'inévidence foncière de ce qu'elle dit (pour reprendre les mots de Jankelé?itch). disproportion en laquelle réside selon l'auteur (...) tout son mystère, en laquelle réside tout son sens. Ce texte court mais dense s'adresse aux musicologues ainsi qu'à tout lecteur ou musicien éclairé voulant densifier son horizon de compréhension de la musique et de ses effets. Il puise ses exemples dans de nombreux corpus : musiques classique et romantique, avant-gardes, jazz, musiques de film."--Page 4 of cover. (shrink)