Everyone knows what is feels like to be in pain. Scraped knees, toothaches, migraines, giving birth, cancer, heart attacks, and heartaches: pain permeates our entire lives. We also witness other people - loved ones - suffering, and we 'feel with' them. It is easy to assume this is the end of the story: 'pain-is-pain-is-pain', and that is all there is to say. But it is not. In fact, the way in which people respond to what they describe as 'painful' has (...) changed considerably over time. In the eighteenth and nineteenth centuries, for example, people believed that pain served a specific (and positive) function - it was a message from God or Nature; it would perfect the spirit. 'Suffer in this life and you wouldn't suffer in the next one'. Submission to pain was required. Nothing could be more removed from twentieth and twenty-first century understandings, where pain is regarded as an unremitting evil to be 'fought'. Focusing on the English-speaking world, this book tells the story of pain since the eighteenth century, addressing fundamental questions about the experience and nature of suffering over the last three centuries. How have those in pain interpreted their suffering - and how have these interpretations changed over time? How have people learnt to conduct themselves when suffering? How do friends and family react? And what about medical professionals: should they immerse themselves in the suffering person or is the best response a kind of professional detachment? (shrink)

Each year thousands of individuals enrol in clinical trials as healthy volunteers to earn money. Some of them pursue research participation as a full-time or at least a part-time job. They call themselves professional or semiprofessional guinea pigs. The practice of paying healthy volunteers raises numerous ethical concerns. Different payment models have been discussed in literature. Dickert and Grady argue for a wage-payment model. This model gives research subjects a standardised hourly wage, and it is based on an assumption that (...) research participation is morally indistinguishable from other forms of unskilled labour. In this paper, I will challenge this assumption. I will argue that human guinea pigging has particular characteristics which taken together make it significantly different from other forms of labour. Participation in research is skill-independent. Healthy volunteers are valuable not because they are skilful persons, but because they are human bodies. The role of research volunteers is mainly passive. They are not asked to produce goods or deliver services. They are paid for enduring unpleasant, painful and risky interventions performed by investigators. Research volunteering involves inherent risks and uncertainties, and subjects have little or no control over their minimisation and materialisation. I conclude that participation in clinical research is a specific kind of activity. It is more like renting out one’s body to strangers, than working. Thus, research participation should not be treated on par with other forms of employment. (shrink)

RD, a 32-year-old male, was admitted to the hospital with hypoxic COVID pneumonia–a potentially life-threatening condition characterized by dangerously low levels of oxygen in the body- during one of the pandemic’s surges. While RD’s age gave the clinical team hope for his prognosis, his ability to recover was complicated by his being unvaccinated and having multiple comorbidities, including diabetes and obesity. His condition worsened to the point that he required extracorporeal membrane oxygenation (ECMO), a machine that maintains the functioning of (...) a person’s heart and lungs. -/- Given its scarcity–only 264 of the over 6,000 hospitals in the United States offer ECMO, according to the Extracorporeal Life Support Organization–as well as its high cost and the inadequate supply of staff required to maintain it, ECMO primarily serves as a bridge to support critically ill patients until they can receive an organ transplant or implanted medical device. For RD, ECMO was started to support him until he could be evaluated for, and possibly receive, a bilateral lung transplant. Despite its intended use as a treatment of last resort, some patients can remain on ECMO for weeks or months. And some are awake, alert, and capable of medical decision-making. -/- RD was one such patient. However, the transplant evaluation committee ruled out RD’s candidacy for bilateral lung transplantation, based on his poor potential for recovery and a lack of family and friends to provide post-transplant support. This determination raised the prospect of continued ECMO treatment being a bridge to nowhere. But RD was comfortable on ECMO and wanted to remain in the ICU. The ICU intensivist contacted the ethics consult service with questions about whether continued ECMO support was medically and ethically inappropriate. (shrink)

Studies show that rejection increases negative affect and aggression and decreases helping behavior toward the excluder. Less is known about emotions and behavior after rejection by a friend for someone else. In two experimental studies (N = 101 and N = 169), we tested the predictions that rejection would feel worse in a close relationship but would result in less aggression and more reconnecting behavior, especially when the reasons for rejection were unknown. The results of study 1 showed that, as (...) expected, among acquaintances, more aggression was noted only after comparative rejection, but among strangers, aggression was also observed after rejection with no stated reason. Negative feelings toward a new acquaintance were only marginally stronger than those toward a stranger in study 1, but study 2 confirmed that rejection by a best friend, and especially comparative rejection by a friend, felt worse than other conditions. Study 2 also showed that reconnecting behavior was more likely to dominate over aggressive behavior between people in close relationships than between strangers. The results are discussed mostly in light of the multimotive model of rejection. (shrink)

Antimicrobial resistance is a major and increasing problem globally. Economics has engaged with this issue increasingly over the last 20 years. Much of this concerns assessments of the cost of various forms of resistance, but it also includes economic analyses of interventions and policies designed to contain resistance. Analysis has, however, thus far largely neglected possible distributional issues associated with such interventions and analysis. The article explores three normative bases for the conduct of economic analysis: welfarism; extra-welfarism focused on health (...) gain; and extra-welfarism focused on capability assessment. It then considers issues intrinsic to antimicrobial resistance in terms of the distributional implications and how these might be handled within economic analyses from each of the normative perspectives, before considering the actual focus of empirical studies on these distributional issues. The article concludes that the different normative starting points for economic analysis will affect how distributional issues are incorporated into analysis, but suggests that all analyses could benefit from greater discussion of these issues. (shrink)

Knowledge about aspects that influence recovery and adaptation in the postacute phase of disabling health events is key to understanding how best to provide appropriate rehabilitation and health services. Qualitative longitudinal research makes it possible to look for patterns, key time points and critical moments that could be vital for interventions and supports. However, strategies that support robust data management and analysis for longitudinal qualitative research in health‐care are not well documented in the literature. This article reviews three challenges encountered (...) in a large longitudinal qualitative descriptive study about experiences of recovery and adaptation after traumatic brain injury in New Zealand, and the strategies and technologies used to address them. These were (i) tracking coding and analysis decisions during an extended analysis period; (ii) navigating interpretations over time and in response to new data; and (iii) exploiting data volume and complexity. Concept mapping during coding review, a considered combination of information technologies, employing both cross‐sectional and narrative analysis, and an expectation that subanalyses would be required for key topics helped us manage the study in a way that facilitated useful and novel insights. These strategies could be applied in other qualitative longitudinal studies in healthcare inquiry to optimise data analysis and stimulate important insights. (shrink)

One of the unmet challenges for risk–benefit assessment in biomedical research is whether there should be an upper limit of risk in non-beneficial studies involving competent and consenting participants, and if yes, how it should be defined. This chapter focuses on this second question. It examines the four dominant regulatory and conceptual approaches to setting a maximal risk threshold in research: no catastrophic harm/risk approach, pure procedural approach, numerical approach, and comparative approach. It then considers the pure procedural approach, which (...) leaves the judgment of risk acceptability to RECs discretion. The approach has significant advantages, but it is not free from certain shortcomings, such as unwarranted diversity and arbitrariness of RECs judgments. The chapter concludes by sketching the outlines of what is referred to as the “ELS procedural approach” that provides RECs with procedural recommendations for identifying an ethically, legally and socially acceptable upper limit of risk in non-beneficial research on volunteers. The ELS procedural approach is an improvement over the pure procedural approach. It is more standardized and accountable, but still context-sensitive and flexible. (shrink)

In contrast to most publications on the ethics of paying research subjects, which start by identifying and analyzing major ethical concerns raised by the practice (in particular, risks of undue inducement and exploitation) and end with a set of—more or less well-justified—ethical recommendations for using payment schemes immune to these problems, this paper offers a systematic, principle-based ethical analysis of the practice. It argues that researchers have aprima faciemoral obligation to offer payment to research subjects, which stems from the principle (...) of social beneficence. This principle constitutes an ethical “spine” of the practice. Other ethical principles of research ethics (respect for autonomy, individual beneficence, and justice/fairness) make up an ethical “skeleton” of morally sound payment schemes by providing additional moral reasons for offering participants (1) recompense for reasonable expenses; and (2a) remuneration conceptualized as a reward for their valuable contribution, provided (i) it meets standards of equality, adequacy and non-exploitation, and (ii) it is not overly attractive (i.e., it does not constitute undue inducement for participation or retention, and does not encourage deceptive behaviors); or (2b) remuneration conceptualized as a market-driven price, provided (i) it is necessary and designed to help the study achieve its social and scientific goals, (ii) it does not reinforce wider social injustices and inequalities; (iii) it meets the requirement of non-exploitation; and (iv) it is not overly attractive. The principle of justice provides a strong ethical reason for not offering recompenses for lost wages (or loss of other reasonably expected profits). (shrink)

Non-beneficial paediatric research is vital to improving paediatric healthcare. Nevertheless, it is also ethically controversial. By definition, subjects of such studies are unable to give consent and they are exposed to risks only for the benefit of others, without obtaining any clinical benefits which could compensate those risks. This raises ethical concern that children participating in non-beneficial research are treated instrumentally; that they are reduced to mere instruments for the benefit of science and society. But this would make the research (...) incompatible with the widely endorsed principle of the primacy of the human subject, which stipulates that the interests of the participating individual should prevail over the interests of science and society. This paper deals with this conflict. It analyses solutions to this problem developed in the literature, and shows that they are unsuccessful. Finally, it offers a new idea of how to reconcile the conduct of non-beneficial paediatric research with the PP. The paper argues for a new formula of the PP, and shows that it implies a specific non-comparative definition of the minimal risk threshold. (shrink)

Events in teaching often bubble up and demand attention because they stay with us long after the moment has passed, causing us to revisit and recreate them, perhaps to ask ourselves whether we might have responded differently. Deeper reflection and wider social enquiry become possible when incidents are recorded over time. Themes are identified and form the basis of theorizing and alternative action. Themes tend to emerge from awareness of our emotional responses to events and through an investigation of the (...) values and beliefs that have informed our reactions to them. Since I am aiming to encourage and strengthen children’s participation in the community of enquiry, a major theme in my own practice is locating barriers to my listening, obstacles that inhibit children’s involvement in philosophical dialogue, whose advocates have emphasized its democratic nature and transformative educational potential. This paper describes an experience of teaching which led me to explore taboos surrounding certain topics in primary schools. In the case reported, I suggest that the subject of ‘secrets’ alludes to wider insecurities in the social construction of intimacy in child and adult relations. These difficulties inhibit the educational process and obscure the voice of the child, even in the context of philosophical dialogue, which aims to increase children’s participation. I consider the moral panic in the UK about the safety of children and the effect on interactions in the ambiguous context of primary schools. I examine the exercise of professional judgement in respect of boundaries of private and public. Conscious of a missed opportunity, I explore secrecy, hiding, concealing and revealing and the part that these play in relationships and in the making of individual identity and the sense of self. Throughout the enquiry I seek to identify obstacles to listening that limit the potential for mutual education. (shrink)

This paper targets an orphan topic in research ethics, namely the so called principle of the primacy of the human being, which states that the interests of the human subject should always take precedence over the interests of science and society. Although the principle occupies the central position in the majority of international ethical and legal standards for biomedical research, it has been commented in the literature mainly in passing. With a few notable exceptions, there is little in-depth discussion about (...) the meaning and role of the principle. Several authors note that the principle is vogue, ambiguous and apparently conflicting with the accepted practice of conducting non-beneficial research on individuals unable to give consent. There are opinions that it is just “a vacuous figure of speech” and should be abandoned. This paper argues that the primacy principle is far from being “a vacuous figure of speech”, rather it should be seen as a threefold concept: a fundamental interpretative rule, a procedural rule, and a substantive rule aimed at protecting research subjects from instrumental treatment and unacceptable risks. This interpretation tracks back to the principle regulatory and normative origins in the Declaration of Helsinki of 1975, but also acknowledges changes in research ethics and practice, which took place at the turn on the twentieth and twenty-first centuries. Thus, the proposed reading of the principle is not only original, but also historically grounded and normatively fruitful. It provides a fresh and ethically rich perspective on extensively debated, but still controversial problem of an upper limit of permissible risks in non-beneficial studies. (shrink)

There is a continuous increase in the number of humanitarian crises around the world. The number of armed conflicts and attacks on civilians is increasing at an alarming rate. Natural disasters compounded by climate change and population growth are also occurring more frequently and with increasing intensity. Given that over 60 million people have been forcibly displaced worldwide, prolonged forced displacement has become the biggest humanitarian, development, political and economic challenge. The needs are increasingly outweighing resources, and humanitarian aid and (...) civil protection are becoming increasingly complex. Funds for humanitarian aid come from the budgets of individual countries. In situations of severe crisis, other state authorities may also decide to grant humanitarian aid from the funds at their disposal. In addition, there are many options for providing humanitarian aid. The purpose of the article is to present methods as crowdfunding for financing humanitarian crises that do not belong to state funds. Most often they come from community collections or projects where more people are involved. It must be admitted, however, that this assistance still seems disproportionately small in relation to the needs. (shrink)

This paper discusses strategic decision making in firms pursuing biotechnology innovation and the influence of risk regulation on firm strategy. Data from three research projects, involving interviews with over 60 managers from agricultural and food related biotechnology companies and also over 60 key participants in the regulatory process in the UK and EC, shows a diversity of strategy and opinion. While some industry representatives identified new risk regulations governing the release of genetically manipulated organisms (GMOs) as the primary constraint on (...) biotechnology innovation, the findings of the study painted a more complex picture. The controversies surrounding the issue of risk regulation and its impact on innovation are best understood if viewed in the context of other political and economic factors. We conclude that the actual impact of risk regulation on industry strategies is probably less than the rhetoric of industry lobbyists would suggest. At the same time, the very act of lobbying so forcefully could lead to a public backlash against industry that would be much more damaging than the regulation itself. (shrink)

The amount allocated to publicly funded health care for 2005/06 in New Zealand, a small country of some four million people, is $NZ 9.68 billion, or 6.2% of GDP, an increase from the 5.7% of GDP in 2000/01. The Minister of Finance has recently signalled that spending in health and education has outpaced economic growth, and that the present rate of growth in health spending, which has grown at about 7% a year over the last decade, is unsustainable. Despite these (...) big funding increases in recent years, the perception of New Zealanders is that the extra spending has made little difference, at least to hospital services and to people’s ability to access treatment. In surveys, health emerges as a leading concern for New Zealanders. Their concern is apparently less about the quality of services, than about their ability to access treatment - whether they will be able to access timely health care when they or their family members need it. (shrink)

The amount allocated to publicly funded health care for 2005/06 in New Zealand, a small country of some four million people, is $NZ 9.68 billion, or 6.2% of GDP, an increase from the 5.7% of GDP in 2000/01. The Minister of Finance has recently signalled that spending in health and education has outpaced economic growth, and that the present rate of growth in health spending, which has grown at about 7% a year over the last decade, is unsustainable. Despite these (...) big funding increases in recent years, the perception of New Zealanders is that the extra spending has made little difference, at least to hospital services and to people’s ability to access treatment. In surveys, health emerges as a leading concern for New Zealanders. Their concern is apparently less about the quality of services, than about their ability to access treatment - whether they will be able to access timely health care when they or their family members need it. (shrink)

Hannah Arendt began her scholarly career with an exploration of Saint Augustine's concept of _caritas_, or neighborly love, written under the direction of Karl Jaspers and the influence of Martin Heidegger. After her German academic life came to a halt in 1933, Arendt carried her dissertation into exile in France, and years later took the same battered and stained copy to New York. During the late 1950s and early 1960s, as she was completing or reworking her most influential studies of (...) political life, Arendt was simultaneously annotating and revising her dissertation on Augustine, amplifying its argument with terms and concepts she was using in her political works of the same period. The disseration became a bridge over which Arendt traveled back and forth between 1929 Heidelberg and 1960s New York, carrying with her Augustine's question about the possibility of social life in an age of rapid political and moral change. In _Love and Saint Augustine_, Joanna Vecchiarelli Scott and Judith Chelius Stark make this important early work accessible for the first time. Here is a completely corrected and revised English translation that incorporates Arendt's own substantial revisions and provides additional notes based on letters, contracts, and other documents as well as the recollections of Arendt's friends and colleagues during her later years. (shrink)

Hannah Arendt began her scholarly career with an exploration of Saint Augustine's concept of _caritas_, or neighborly love, written under the direction of Karl Jaspers and the influence of Martin Heidegger. After her German academic life came to a halt in 1933, Arendt carried her dissertation into exile in France, and years later took the same battered and stained copy to New York. During the late 1950s and early 1960s, as she was completing or reworking her most influential studies of (...) political life, Arendt was simultaneously annotating and revising her dissertation on Augustine, amplifying its argument with terms and concepts she was using in her political works of the same period. The disseration became a bridge over which Arendt traveled back and forth between 1929 Heidelberg and 1960s New York, carrying with her Augustine's question about the possibility of social life in an age of rapid political and moral change. In _Love and Saint Augustine_, Joanna Vecchiarelli Scott and Judith Chelius Stark make this important early work accessible for the first time. Here is a completely corrected and revised English translation that incorporates Arendt's own substantial revisions and provides additional notes based on letters, contracts, and other documents as well as the recollections of Arendt's friends and colleagues during her later years. (shrink)

The concept of biodiversity has played a central role within conservation biology over the last thirty years. Precisely how it should be understood, however, is a matter of ongoing debate. In this paper we defend what we call a classic multidimensional conception of biodiversity. We begin by introducing two arguments for eliminating the concept of biodiversity from conservation biology, both of which have been put forward in a recent paper by Santana. The first argument is against the concept’s scientific usefulness. (...) The other is against its value as a target of conservation. We show that neither of these objections is successful against the classic multidimensional conception of biodiversity. Biodiversity thus understood is important from a scientific perspective, because it plays important explanatory roles within contemporary ecology. Moreover, although it does not encompass all valuable features of the natural world, this does not show that we should abandon it as a target of conservation. Instead, biodiversity should be conceived as one of many grounds of value associated with ecosystems. This is consistent with concluding that a central aim of conservationists should be to protect biodiversity. (shrink)

A fundamental question in biology is whether phenotypes can be predicted by ecological or genomic rules. At least five cases of convergent evolution of the crab‐like body plan (with a wide and flattened shape, and a bent abdomen) are known in decapod crustaceans, and have, for over 140 years, been known as “carcinization.” The repeated loss of this body plan has been identified as “decarcinization.” In reviewing the field, we offer phylogenetic strategies to include poorly known groups, and direct evidence (...) from fossils, that will resolve the history of crab evolution and the degree of phenotypic variation within crabs. Proposed ecological advantages of the crab body are summarized into a hypothesis of phenotypic integration suggesting correlated evolution of the carapace shape and abdomen. Our premise provides fertile ground for future studies of the genomic and developmental basis, and the predictability, of the crab‐like body form. (shrink)

The paper aims at outlining the main points in stoic theology: Stoics' attitude to the Greek mythology, the proofs for god's existence, the concept of divinity and the characteristics of god according to the names given to him within the Stoic physics. Finally, the concepts of fate and providence are mentioned as they are strictly linked to the concept of god-logos and lead to most important problems of human freedom and theodicy. The paper does not include all the discussions held (...) by the stoics and their opponents over the question of divinity, as they were extant and well elaborated; it proves, though, the unique position theology has in Stoic philosophy as the one to explain the very sense of human existence and the world. (shrink)

This article signals at a dearth of critical engagement with Thomas Carlyle's Presbyterian heritage resulting from the received whiggish narrative of his Calvinism as unenlightened, anachronistic, and backward-looking. It proceeds to challenge this view by examining closely Carlyle's creative use of key Calvinist concepts in his cosmopolitan and enlightened dialogue with the contemporary periodical press over British and European cultures. Carlyle is shown to be an adept purveyor both of the Edinburgh Magazine's enlightened idiom and of Blackwood's morally conservative and (...) artistically cosmopolitan agendas, while also making creative capital of the Anti-Jacobin's powerful Gothic imagery and of the critical verve of the Westminster Review. The main addressees of Carlyle's reading of the signs of the times, I argue, are contemporary Whigs. Carlyle's depiction of Macaulay as a ‘spiritual hippopotamus’ spells Carlyle's broader critique of the modern lack of imagination of the spiritual which sponsors deterministic religious and secular readings of reality. Carlyle displays his enlightened Calvinist perspective in discussing the French Revolution through such key Scottish Enlightenment concepts as free will, conscience, civilisational and moral progress, and divine providence. Insightful and creative use of his inherited Scottish Calvinist heritage characterises Carlyle's open, cosmopolitan reading of the signs of the times. (shrink)

While it has often been assumed that, in humans, synonymous mutations would have no effect on fitness, let alone cause disease, this position has been questioned over the last decade. There is now considerable evidence that such mutations can, for example, disrupt splicing and interfere with miRNA binding. Two recent publications suggest involvement of additional mechanisms: modification of protein abundance most probably mediated by alteration in mRNA stability1 and modification of protein structure and activity,2 probably mediated by induction of translational (...) pausing. These case histories put a further nail into the coffin of the assumption that synonymous mutations must be neutral. BioEssays 29:515–519, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

Symbolic Annihilation or Alternative Femininity? The Portrayal of Women in Selected Polish Advertisements The year 1989 marks the beginning of sweeping political, economic and social changes in Poland. Since that time an expansion of women into top professional positions can be observed. Data from the last national census clearly indicate that women in Poland are better educated than their male counterparts, increasingly careeroriented as well as aggressively pursuing managerial occupations. A modern woman is, by popular belief, no longer obliged to (...) conform to the so-called dominant or emphasized [i.e. hegemonic] form of femininity. There appears to be greater social latitude for her professional development. The paper explores whether print advertisements of certain products incorporate new powerful discourse of femininity. The three advertised products and services selected for the analysis have been commonly associated in Poland with the dominant form of masculinity. Consequently, it is interesting to examine whether women function there, and if so, how. The analyzed advertisements have been collected over the period of one year from three magazines addressed to the emerging Polish middle class. Drawing on Goffman's concepts of function ranking and ritualization of subordination as well as Critical Discourse Analysis, I will attempt to determine whether the selected print advertisements reflect the new femininity in Poland. (shrink)

Numerous authors indicate that the influence of academic education extends beyond the growth of specialized knowledge gained by the graduates. Scholars are trying to identify and examine the potential impact of higher learning on students’ attitudes and choices. One of the dimensions considered by the researchers is the effect of university training on students’ moral choices. Our paper attempts to identify differences between the students’ declared moral choices and their majors (fields of studies). Working with a sample of university students (...) of Economics and Sociology (N = 181), and using three variants of the Trolley Problem, the subjects’ responses are used to identify the similarities and differences between their choices. The participants were asked to respond to three hypothetical situations regarding a runaway trolley. Their decision in the first scenario could save a person’s life or let her be run over by the trolley. In the second scenario, their decision could either let one person die and save five lives or save one life and let five people be killed. These two scenarios required pulling a lever to switch the trolley from one track to another. The third scenario requires pushing an obese person in front of the runaway trolley to stop it from killing five persons. As expected, we found a significant difference between the two groups (the economists and the sociologists) in the case of our third scenario, however, we found no evidence supporting the indoctrination hypothesis. We conclude that the existing differences between the choices made by the future economists and sociologists may support the preselection hypothesis. (shrink)

In an influential paper, James Lenman argues that consequentialism can provide no basis for ethical guidance, because we are irredeemably ignorant of most of the consequences of our actions. If our ignorance of distant consequences is great, he says, we can have little reason to recommend one action over another on consequentialist grounds. In this article, I show that for reasons to do with statistical theory, the cluelessness objection is too pessimistic. We have good reason to believe that certain patterns (...) of action will tend to have better consequences, and we have good reason to recommend acting in accordance with strategies based on those advantageous patterns. I close by saying something about the strategies that this argument should lead us to favour. (shrink)

"Of all creatures women be best, / Cuius contrarium verum est": Gendered Power in Selected Late Medieval and Early Modern Texts The aim of this paper is to examine images of the relationship between men and women in selected late medieval and early modern English texts. I will identify prevalent ideology of representation of women as well as typical imagery associated with them. I will in particular argue that men whose homosocial laughter performs a solidifying function of their community seek (...) to reiterate their superiority over women through seemingly playful and inclusive humour. I will attempt to show that what appears to be good-natured entertainment is actually a weapon used against women who, often accused of no sense of humour, are ridiculed and commanded to succumb to male authority. I will also discuss the triumphant tone of both poems and dramatic writings whose cheerful tone functions to marginalize women and to reinforce the misogynistic foundations of public life. (shrink)

For her entire childhood, Joanna's father, Bob, had a ritual: wake up at dawn, walk the dog, and sit down at the kitchen table with a blank pad of paper and plenty of colored markers to craft notes for his two children. Over the years, word games and puzzles for five-year-olds morphed into thoughtful guidance and reflections for his teenagers approaching adulthood. Now, with more than 3,500 of her father's colorful notes in hand, Joanna has decided that the (...) lessons tucked inside are worth sharing. Folded Wisdom highlights the collection of Bob's notes, telling a story filled with universal values that encourages meaningful self-reflection about how we all face successes and failures; express happiness and sadness; and communicate frustration, praise, and love to one another. Heartfelt and full of possibility for the future, a father's folded notes and drawings are timeless reminders of love. (shrink)

The debates about qualia are common in contemporary analytical philosophy, especially in the area of philosophy of mind or epistemology. Notwithstanding the significance of this notion in present-day investigations, there still appears to be a lack of agreement over how to understand the term “quale”. Due to this fact, our goal is to shed light on the concept of quale as it entered the modern history of philosophy. Strictly speaking, our concern shall be devoted to the American pragmatist philosophy of (...) C. S. Peirce and C. I. Lewis. Therefore, we intend to outline the understanding of quale within Peirce's theory of categories at the beginning, and afterwards we shall present Lewis' remarks on quale in the context of his theory of the given. This approach will not only provide the grounds for relating Peirce's and Lewis' views with each other, but also it will let us interpret Lewis' notion of quale within the pragmatic framework. (shrink)

The principal aim of this paper is to analyse the notion of identity and to clarify terminology relevant to this notion. I characterize two main types of identity occuring between objects: abstract identity and numerical identity. I introduce further subtypes and try to point out some of the relations between objects which are identical numerically, and those which are identical abstractly. Some of the qualities of identity are described. Then, I work over relationship between identity and the other relations: sameness, (...) kinship, likeness, equivalence, equality and difference. I also point out some of consequences of the view which reduces synonimity of expression to identity between these expressions' meanings. Finally, I consider the criterion which would make identification of identity possible. (shrink)

A scientifically proven method to overcome obstacles and make choices that lead us closer to our goals. WITH A FOREWORD BY MARTINA NAVRATILOVA What do weight gain, poor employee engagement, and climate change all have in common? All three are persistent problems for which solutions are known and readily available. Yet, on an individual and collective level, we continually make choices that lead us not closer to but further away from our stated objectives. Whether we choose the burger and fries (...) over the salad, top-down management over collaboration, or leniency over rigor in combatting climate change, it all comes down to the same thing. The Choice Point. The moment at which we each choose to take an action that we know will undermine our success, but we do it anyway. The Choice Point explains how we experience thousands of thoughts every day: 80 percent are negative, while only 5 percent are new thoughts. We make most of our decisions within two seconds, using mental autopilot systems that we've built through years of experiences, and some of our thoughts (like quitting during a challenge) can compromise our goals. But there's a strategy to change this: Functional Imagery Training (FIT). FIT teaches us how to pick the thoughts that deserve our attention, and how to stop the other, negative thoughts from impacting our actions. Through FIT, we can pause decisions that would typically conflict with our goals, lengthen our Choice Point, and go from passenger to driver of our own minds. Initially developed in 2005 by academics in the UK and Australia, with formal principles emerging through research in 2018, FIT blends motivational interviewing with imagery into a user-friendly model so we can learn, adapt, and adjust our behavior to go beyond what we think is possible. (shrink)

In the interview conducted with Giovanna Borradori, after the attack on the World Trade Centre, in September 2001, Jacques Derrida is pressed to specify connections between his own thinking, Heidegger's deployment of the term ‘event’, and the use of the term ‘event’ to pick out the unprecedented character of that attack. Derrida intimates that the attack is, perhaps, not as unprecedented, not the ‘wholly other’ which it has been framed as being. His reading of that event is to move it (...) from a naive status, as ‘wholly other’, to a philosophically inflected thinking of the political, in the mode of the ‘wholly otherwise’, that is, in a sense to be made out here, whereby politics takes precedence over physics, as the originator of the basic components to be thought, and whereby the future takes precedence over the past, as the site at which what is arrives. The principal aim of this article is to consider how to think this counter-factual ontology, in the mode of a future anteriority. The article will set out Heidegger's move from affirming a fundamental ontology, of Dasein, to an ontology in parentheses (vom Ereignis) but will show how both of these are objectionable, on different counts, to Derrida and to Levinas. Derrida explores the options of supplementing an inadmissible thetic stance, with respect to the future, and therefore with respect to what there is, by developing the notion of the prosthetic, that which stands in for the impossible, timelessly asserted thesis. Levinas invents a new mode of phenomenology which opens a route into this ‘wholly otherwise’. These two strands of enquiry contribute to an analysis displacing these versions of ontology, in favour of a reformulation of political ontology. A subsidiary aim is to clarify Derrida's reservations with respect to the Heideggerian notion of the event. These reservations about Heidegger's usage throw light on his reluctance to deploy the term, within an analysis of the destruction of the World Trade Centre. (shrink)

Wilhelm Dilthey in WrocławThe article above discusses 11 years of Wilhelm Dilthey’s creative presence in Wrocław, a philosopher whose contribution to the European culture has been never questioned. Dilthey was appointed to the University of Wrocław in March 1871. Same year in October, he moved to Wrocław, took over the department of philosophy from Christlieb Julius Braniβ and started academic lectures in autumn. Acclimatizing in the Silesian capital was dif ficult for the philosopher, in his letters he complained about the (...) climate and provinciality of the city. It has changed over time, so that Dilthey finally adjusted to the environment. It happened because of numerous connections with the people from the university, among others with Graf Yorck von Wartenburg, but not only. In Dilthey’s biography, years in Wrocław were extremely prolific. In Wrocław Dilthey matured to the work of his life: Introduction to the Human Sciences, called in the subject literature the “crowning of the period in Wrocław”. He presented the concept of his work in a letter, among others, to Theodor Althof f, an of ficial from the Prussian Ministry of Culture. The preserved sketch of the letter is interesting because of its concept, but also because it shows a certain dependence of onetime philosophers on the state system. The article above contains an annex—a translation of this letter into Polish. Dilthey was a lecturer at the University of Wrocław until the end of the summer semester in 1882, after that he was appointed to Berlin in July 1882. (shrink)

This piece uses a feminist approach to explore various aspects of ‘commodification’ in the lives and work of those teaching and researching in UK universities, and in particular its gender dimensions. After setting a historical context for the radical transformation of UK universities during the 1980s, it considers how this transformation was experienced by academics in terms of alienation, anxiety and accountability. Key features of that experience are loss of autonomy and control to the external power of competition and managerialism, (...) insecurity and casualization in employment, and exposure to increasing judgemental scrutiny. For women academics job insecurity and discrimination continue to be disproportionately important, although some of the challenges to old established academic convention and practice have opened up real possibilities to progress more pro-women agendas. In the future they will confront quite depressing developments in the reconstruction of academic identities and labour, but have the legacy of the gains/insights of feminist analysis and politics over the last twenty years with which to do so. (shrink)

In this article I propose a view which explains how it is possible that the disagreement concerning clear cases of a given vague predicate is genuine, whereas that concerning borderline cases is faultless. I take the possibility of faultless disagreement concerning borderline cases to be an important characteristic of vague predicates and in my view any adequate theory of vagueness should account for it. My proposal might be called “contextual supervaluationism” and it is inspired by Kölbel's relativist view from his (...) paper “Vagueness as Semantic”. Following Kölbel I claim that the range of admissible sharpenings assumed by supervaluationism is context‐dependent, but contrary to him I maintain that we need supertruth as well as truth at a sharpening. Moreover – again unlike Kölbel – I argue that utterances concerning borderline cases are permissible. I claim, however, that such utterances should be assertives rather than assertions, since they express only a weak belief of the speaker. It is the different illocutionary forces of utterances concerning clear cases and borderline cases that make it possible to explain the distinct nature of disagreements over such cases. (shrink)

The importance of forests is reflected in the national forest legislation which has been developed and implemented in European countries over recent years. Due to regional and national specificities, forest regulations include culturally immersed terms specific to the described area. The aim of this paper is to analyses the culturally driven legal terms existing in specific legal regulations concerning forestry in Germany, the United Kingdom, the United States of America and Poland, and identify possible ways of translating them. In order (...) to take the interdisciplinary nature of the issue into account, the degree of hybridity of the selected texts will be examined by means of corpus analysis. The methodology applied in the paper uses a comparative approach. Additionally, the authors also resort to the aforementioned corpus analysis, as well as the analysis of comparable texts and the analysis of terminology according to the three categories of equivalence as determined by Šarčević, and the techniques of providing equivalents for non-equivalent or partially equivalent terms as research methods. The material used for analysis comes from selected German, English and Polish legal acts regulating forest management and maintenance that are considered as corpora for the selection of culturally immersed terminology, namely: the Polish Act on Forests of 28th September 1991 [Ustawa z dnia 28 września 1991 r. o lasach], Title 16 U.S. Code Chapter 2—National Forests, Forestry Act 1967, Chapter 10, German Forestry Act 1975 [Gesetz zur Erhaltung des Waldes und zur Förderung der Forstwirtschaft von 1975]. The paper concerns potential problems that could occur in the translation of culturally immersed legal terminology due to the terms’ rigidity and high degree of specificity. The studies presented will allow conclusions to be drawn regarding the possibilities and strategies for translating culturally immersed terms. In addition, the availability of terminological dictionaries for these language pairs will be discussed. (shrink)

The question of enhancement occupies a prominent place not only in current bioethical debates but also in wider public discussions about our human future. In all of these, the problem of enhancement is usually articulated via two sets of questions: moral questions over its permissibility, extent and direction; and technical questions over the feasibility of different forms of regenerative and synthetic alterations to human bodies and minds. This article argues that none of the dominant positions on enhancement within the field (...) of bioethics is entirely satisfactory due to the limited, monadic, pre-technological and non-cultural conception of the human that is adopted in these models. Critically engaging with both opponents of enhancement (Habermas) and its advocates (Harris, Agar, Bostrom, Dworkin), Zylinska also takes some steps towards outlining a nonnormative ethics of enhancement. The latter sees its human and non-human subjects as always already enhanced, and hence dependent, relational and coevolving with technology. (shrink)

Why do we find agents less blameworthy when they face mitigating circumstances, and what does this show about philosophical theories of moral responsibility? We present novel evidence that the tendency to mitigate the blameworthiness of agents is driven both by the perception that they are less normatively competent—in particular, less able to know that what they are doing is wrong—and by the perception that their behavior is less attributable to their deep selves. Consequently, we argue that philosophers cannot rely on (...) the case strategy to support the Normative Competence theory of moral responsibility over the Deep Self theory. However, we also outline ways in which further empirical and philosophical work would shift the debate, by showing that there is a significant departure between ordinary concepts and corresponding philosophical concepts, or by focusing on a different type of coherence with ordinary judgments. (shrink)

A growing body of research is exploring corporate communication in relation to corporate social responsibility (CSR) activities on social media (SM). Nonetheless, while these studies have shown that SM communication may be an effective tool for reaching and engaging various stakeholders, how the design of corporate CSR communication engenders trustworthiness has yet to be examined. To address this gap, we suggest that SM communication may include important signals related to trust; thus, we investigate whether companies use sources of trustworthiness (reputation, (...) performance, and appearance) while communicating with stakeholders and the response of the latter to such communication. Our empirical analysis is based on a database containing over 66,000 CSR-related messages from eight companies focusing on communication extracted from Twitter. These data are coded according to three sources of trustworthiness and two dimensions of CSR communication (social and environmental). Our findings indicate that all three attributes of trustworthiness are used by companies in their CSR social media communication. We also document how corporate efforts to use CSR communication that engenders trustworthiness influence stakeholder engagement. Our study therefore contributes to the literature on trust in relation to CSR by illustrating the importance of signaling that includes different sources of trustworthiness or their combination in corporate communication. By analyzing how the various trust attributes included in CSR communication affect SM reactions, we also identify which attributes lead to greater stakeholder engagement overall, particularly for the two analyzed dimensions of CSR communication. (shrink)

The purpose of this study was to investigate the mediational role of relational psychological contract in social beliefs and work input attitude dependency. We analyzed data taken from employees in four different organizations operating in the Pomeranian market. A mediation analysis showed a strongly mediating role of psychological contract in the negative relationship between perception of life as a zero-sum game and work input. The motivational effect of the relational psychological contract, that is the role of job security, interesting work, (...) a career in the company, opportunities for promotion and other HRM practices prevail over the significance of personal beliefs, especially when these are negative. If the company lacks the appropriate HRM systems then day-to-day social exchanges can be crucial in modifying the social beliefs of the employee. (shrink)

The paper presents findings from an ethnography of dysmorphology, a specialism in genetic medicine, to explore genetic counselling as a process through which parents ‘become informed.’ Current professional and policy debate over the use of genetic technology in medicine emphasises the need for informed choice making, and for genetic services that provide parents with what is referred to as ‘non-directive genetic counselling.’ In the paper the process of becoming informed is shown to be very specific and to have its own (...) effects. Specifically, genetics is performed in dysmorphology as a space of ambiguity and uncertainty. In addition, parents are engaged by the clinic as participants in the very processes through which their child, and perhaps their family, are clinically classified. The paper examines the effects of parents’ immersion in this clinical space of deferral to suggest how the need for reproductive choice, and calculation, is predicated upon clinical processes that shift parents between the experience of definition and uncertainty. The paper thus troubles simple stories about autonomous and informed choice, particularly reproductive choice, as icons of contemporary versions of what it is to be fully human. (shrink)

This book is a tribute to Professor Ewa Orłowska, a Polish logician who was celebrating the 60th year of her scientific career in 2017. It offers a collection of contributed papers by different authors and covers the most important areas of her research. Prof. Orłowska made significant contributions to many fields of logic, such as proof theory, algebraic methods in logic and knowledge representation, and her work has been published in 3 monographs and over 100 articles in internationally acclaimed journals (...) and conference proceedings. The book also includes Prof. Orłowska’s autobiography, bibliography and a trialogue between her and the editors of the volume, as well as contributors' biographical notes, and is suitable for scholars and students of logic who are interested in understanding more about Prof. Orłowska’s work. (shrink)

This paper introduces Basic Intuitionistic Set Theory BIST, and investigates it as a first-order set theory extending the internal logic of elementary toposes. Given an elementary topos, together with the extra structure of a directed structural system of inclusions on the topos, a forcing-style interpretation of the language of first-order set theory in the topos is given, which conservatively extends the internal logic of the topos. This forcing interpretation applies to an arbitrary elementary topos, since any such is equivalent to (...) one carrying a dssi. We prove that the set theory BIST+Coll is sound and complete relative to forcing interpretations in toposes with natural numbers object . Furthermore, in the case that the structural system of inclusions is superdirected, the full Separation schema is modelled. We show that all cocomplete and realizability toposes can be endowed with such superdirected systems of inclusions.A large part of the paper is devoted to an alternative notion of category-theoretic model for BIST, which, following the general approach of Joyal and Moerdijkʼs Algebraic Set Theory, axiomatizes the structure possessed by categories of classes compatible with BIST. We prove soundness and completeness results for BIST relative to the class-category semantics. Furthermore, BIST+Coll is complete relative to the restricted collection of categories of classes given by categories of ideals over elementary toposes with nno and dssi. It is via this result that the completeness of the original forcing interpretation is obtained, since the internal logic of categories of ideals coincides with the forcing interpretation. (shrink)

This paper introduces Basic Intuitionistic Set Theory BIST, and investigates it as a first-order set theory extending the internal logic of elementary toposes. Given an elementary topos, together with the extra structure of a directed structural system of inclusions on the topos, a forcing-style interpretation of the language of first-order set theory in the topos is given, which conservatively extends the internal logic of the topos. This forcing interpretation applies to an arbitrary elementary topos, since any such is equivalent to (...) one carrying a dssi. We prove that the set theory BIST+Coll is sound and complete relative to forcing interpretations in toposes with natural numbers object. Furthermore, in the case that the structural system of inclusions is superdirected, the full Separation schema is modelled. We show that all cocomplete and realizability toposes can be endowed with such superdirected systems of inclusions.A large part of the paper is devoted to an alternative notion of category-theoretic model for BIST, which, following the general approach of Joyal and Moerdijkʼs Algebraic Set Theory, axiomatizes the structure possessed by categories of classes compatible with BIST. We prove soundness and completeness results for BIST relative to the class-category semantics. Furthermore, BIST+Coll is complete relative to the restricted collection of categories of classes given by categories of ideals over elementary toposes with nno and dssi. It is via this result that the completeness of the original forcing interpretation is obtained, since the internal logic of categories of ideals coincides with the forcing interpretation. (shrink)

We explore and critically reflect on the process of science and engineering research assistant skill development both within laboratory-based research teams and, when no team is present, within the faculty supervisor-research assistant interactions. Using a performance-based measure of research skill development, we identify research assistants who, over the course of an academic year of service as a researcher, markedly developed, modestly developed, or failed to develop their research skills. Interviews with these research assistants and their faculty supervisors, seen through the (...) lens of cognitive apprenticeship, provide insight into this variation. We found that within the contours of supervisory relationships and research teams, research skill development is indelibly shaped, for better or worse, by supervisor influence and abundant trial-and-error. (shrink)

The Agreement-Based Tests for Context Sensitivity In my paper, I present and discuss Cappelen and Lepore's context sensitivity tests, which appeal to says-that reports. In Relativism and Monadic Truth Cappelen and Hawthorne criticize those tests and propose agreement-based tests instead. I argue that such tests do not fare much better. The original Cappelen and Lepore's tests presupposed a minimal notion of says-that. One might postulate a parallel notion of "thin" agreement, according to which people agree that p if they all (...) believe the minimal proposition that p. In this sense we might say - as opposed to what Cappelen and Hawthorne say - that A and B agree that Nicola is smart, even though A thinks that she is smart because she stands way back against strong servers, while B thinks that she is smart because she invested all her money in penny stocks. The paper ends with a critical gloss concerning the case in which Joe Coach predicates tall of people who are over six-foot-eight and Joe Normal, who applies tall to anyone over six-foot tall. I conclude that agreement and disagreement tests are poor indicators of context sensitivity, since their result depends on the prior theoretical standpoint one adopts. (shrink)

The main focus of this thesis is indeterminate identity and its relations to vague objects and to imprecise designation. Evans's argument concerning indeterminate-identity statements is often regarded as a proof that vague objects cannot exist. In chapter I I try to argue that the argument may be refuted by vague objects theorists. In chapter II I present various accounts of what indeterminate identity between objects may consist in and three different characteristics of it. I argue that there are objects whose (...) identity is indeterminate and that such indeterminacy is ontic in the sense that it concerns individuation and spatio-temporal boundaries of objects. I also formulate the argument showing that terms designating indeterminately identical objects cannot be precise designators. Chapter III is devoted to problems concerning vagueness and identity-over-time. The indeterminate answer to the questions concerning diachronic identity in puzzling cases can be regarded as the correct response by both endurantists and perdurantists. However, while for perdurantists the whole vagueness of persistence conditions is a conceptual matter, for endurantists it deserves the name of "ontic vagueness". Chapter IV focuses on questions concerning vagueness and identity-at-a-time. I offer a new solution to the problem of the many, according to which in each case in which the problem arises there is - contrary to appearances - only one object present. The problem arises because each such object has many precisifications, which nevertheless have no ontological significance. I also propose a new account of what it takes for an object to be vague. Chapter V deals with indeterminate identity in the domain of quanta. The first part investigates the various problems concerning identity and individuation of quantum particles, whereas the second part is devoted to analysis and critique of E. J. Lowe's example of alleged indeterminate identity-over-time between electrons. (shrink)

Patients have received experimental pharmaceuticals outside of clinical trials for decades. There are no industry-wide best practices, and many companies that have granted compassionate use, or ‘preapproval’, access to their investigational products have done so without fanfare and without divulging the process or grounds on which decisions were made. The number of compassionate use requests has increased over time. Driving the demand are new treatments for serious unmet medical needs; patient advocacy groups pressing for access to emerging treatments; internet platforms (...) enabling broad awareness of compelling cases or novel drugs and a lack of trust among some that the pharmaceutical industry and/or the FDA have patients’ best interests in mind. High-profile cases in the media have highlighted the gap between patient expectations for compassionate use and company utilisation of fair processes to adjudicate requests. With many pharmaceutical manufacturers, patient groups, healthcare providers and policy analysts unhappy with the inequities of the status quo, fairer and more ethical management of compassionate use requests was needed. This paper reports on a novel collaboration between a pharmaceutical company and an academic medical ethics department that led to the formation of the Compassionate Use Advisory Committee. Comprising medical experts, bioethicists and patient representatives, CompAC established an ethical framework for the allocation of a scarce investigational oncology agent to single patients requesting non-trial access. This is the first account of how the committee was formed and how it built an ethical framework and put it into practice. (shrink)

Multiteam systems are complex organizational forms comprising interdependent teams that work towards their own proximal goals within and across teams to also accomplish a shared superordinate goal. MTSs operate within high-stakes, dangerous contexts with high consequences for suboptimal performance. We answer calls for nuanced exploration and cross-context comparison of MTSs “in the wild” by leveraging the MTS action sub-phase behavioral taxonomy to determine where and how MTS failures occur. To our knowledge, this is the first study to also examine how (...) key MTS attributes influence MTS processes and performance. We conducted historiometric analysis on 40 cases of failed MTS performance across various contexts to uncover patterns of within- and between-team behaviors of failing MTSs, resulting in four themes. First, component teams of failing MTSs over-engaged in within-team alignment behaviors by enacting acting, monitoring, and recalibrating behaviors more often within than between teams. Second, failing MTSs over-focused on acting behaviors and tended to not fully enact the action sub-phase cycle. Third and fourth, boundary status and goal type exacerbated these behavioral patterns, as external and physical MTSs were less likely to enact sufficient between-team behaviors or fully enact the action sub-phase cycle compared to internal and intellectual MTSs. We propose entrainment as a mechanism for facilitating MTS performance wherein specific, cyclical behavioral patterns enacted by teams align to facilitate goal achievement via three multilevel behavioral cycles. We argue that the degree to which these cycles are aligned both between teams and with the overarching MTS goal determines whether and how an MTS fails. Our findings add nuance beyond single-context MTS studies by showing that the identified behavioral patterns hold both across contexts and almost all types of MTS action-phase behaviors. We show that these patterns vary by MTS boundary status and goal type. Our findings inform MTS training best practices, which should be structured to integrate all component teams and tailored to both MTS attributes and situation type. (shrink)

‘‘Undone science’’ refers to areas of research that are left unfunded, incomplete, or generally ignored but that social movements or civil society organizations often identify as worthy of more research. This study mobilizes four recent studies to further elaborate the concept of undone science as it relates to the political construction of research agendas. Using these cases, we develop the argument that undone science is part of a broader politics of knowledge, wherein multiple and competing groups struggle over the construction (...) and implementation of alternative research agendas. Overall, the study demonstrates the analytic potential of the concept of undone science to deepen understanding of the systematic nonproduction of knowledge in the institutional matrix of state, industry, and social movements that is characteristic of recent calls for a ‘‘new political sociology of science.’’. (shrink)