The ethical theories employed in health care today assume, in the main, a modern Western philosophical framework. Yet the diversity of cultural and religious assumptions regarding human nature, health and illness, life and death, and the status of the individual suggest that a cross-cultural study of health care ethics is needed. A Cross-Cultural Dialogue on Health Care Ethics provides this study. It shows that ethical questions can be resolved by examining the ethical principles present in each culture, critically assessing each (...) value, and identifying common values found within all traditions, It encourages the development of global awareness and sensitivity to and respect for the diversity of peoples and their values and will advance understanding as well as help to foster a greater balance and a fuller truth in consideration of the human condition and what makes for health and wholeness. (shrink)

Humans are an exceptionally cooperative species, but there is substantial variation in the extent of cooperation across societies. Understanding the sources of this variability may provide insights about the forces that sustain cooperation. We examined the ontogeny of prosocial behavior by studying 326 children 3–14 y of age and 120 adults from six societies (age distributions varied across societies). These six societies span a wide range of extant human variation in culture, geography, and subsistence strategies, including foragers, herders, horticulturalists, and (...) urban dwellers across the Americas, Oceania, and Africa. When delivering benefits to others was personally costly, rates of prosocial behavior dropped across all six societies as children approached middle childhood and then rates of prosociality diverged as children tracked toward the behavior of adults in their own societies. When prosocial acts did not require personal sacrifice, prosocial responses increased steadily as children matured with little variation in behavior across societies. Our results are consistent with theories emphasizing the importance of acquired cultural norms in shaping costly forms of cooperation and creating cross-cultural diversity. (shrink)

This study analyzes the influence of grandmothers’ household residency on the presence of low height-for-age and excessive fat, waist circumference, and sum of triceps and subscapular skinfolds in a sample of 247 6- to 8-year-old urban Maya children from Yucatan, Mexico. Between September 2011 and January 2014, we obtained anthropometric and body composition data from children and mothers, as well as socioeconomic characteristics of participants and households. Grandmothers’ place of residence was categorized as either in the same household as their (...) grandchildren or in separate households. Multiple logistic regression models were used to analyze the association between grandmothers’ residency and outcome variables. Models were adjusted for maternal anthropometric characteristics and the following socioeconomic variables: family size, location, maternal education, monthly family income, and household crowding. Models showed that the presence of grandmothers in their grandchildren’s households was not associated with any of the outcome variables. In contrast, larger family size, overcrowding in the household, and lower family income predicted low height-for-age in children. Larger family size decreased the risk for being overweight based on the three parameters of body composition. Overcrowding in the household increased the risk for greater skinfolds thickness, while low family income increased the risk for higher fat mass index. The residency of grandmothers in their adult daughters’ households is not significantly associated with the outcome variables in this sample of urban Maya families. Instead, maternal anthropometric characteristics and socioeconomic conditions of the family have a greater influence on the overall growth of children. (shrink)

When the COVID-19 surge hit New York City hospitals, the Division of Medical Ethics at Weill Cornell Medical College, and our affiliated ethics consultation services, faced waves of ethical issues sweeping forward with intensity and urgency. In this article, we describe our experience over an eight-week period (16 March through 10 May 2020), and describe three types of services: clinical ethics consultation (CEC); service practice communications/interventions (SPCI); and organizational ethics advisement (OEA). We tell this narrative through the prism of time, (...) describing the evolution of ethical issues and trends as the pandemic unfolded. We delineate three phases: anticipation and preparation, crisis management, and reflection and adjustment. The first phase focused predominantly on ways to address impending resource shortages and to plan for remote ethics consultation, and CECs focused on code status discussions with surrogates. The second phase was characterized by the dramatic convergence of a rapid increase in the number of critically ill patients, a growing scarcity of resources, and the reassignment/ redeployment of staff outside their specialty areas. The third phase was characterized by the recognition that while the worst of the crisis was waning, its medium- and long-term consequences continued to pose immense challenges. We note that there were times during the crisis that serving in the role of clinical ethics consultant created a sense of dis-ease as novel as the coronavirus itself. In retrospect we learned that our activities far exceeded the familiar terrain of clinical ethics consultation and extended into other spheres of organizational life in novel ways that were unanticipated before this pandemic. To that end, we defined and categorized a middle level of ethics consultation, which we have termed service practice communication intervention (SPCI). This is an underappreciated dimension of the work that ethics consult services are capable of in times of crisis. We believe that the pandemic has revealed the many enduring ways that ethics consultation services can more robustly contribute to the ethical life of their institutions moving forward. (shrink)

Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. We developed the Non-Coding RNA Ontology (NCRO) to handle this situation. By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of (...) large amounts of ncRNA biological and clinical data. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

In The Crane's Walk, Jeremy Barris seeks to show that we can conceive and live with a pluralism of standpoints with conflicting standards for truth--with the truth of each being entirely unaffected by the truth of the others. He argues that Plato's work expresses this kind of pluralism, and that this pluralism is important in its own right, whether or not we agree about what Plato's standpoint is.The longest tradition of Plato scholarship identifies crucial faults in Plato's theory of (...) Ideas. Barris argues that Plato deliberately displayed those faults, because he wanted to demonstrate that basic kinds of error or illogic have dimensions that are crucial to the establishing of truth. These dimensions legitimate a paradoxical coordination of logically incompatible conceptions of truth. Connecting this idea with emerging currents of Plato scholarship, he emphasizes, in addition to the dialogues' arguments, the importance of their nonargumentative features, including drama, myths, fictions, anecdotes, and humor. These unanalyzed nonargumentative features function rigorously, as a lever with which to examine the enterprise of rational argument itself, without presupposing its standards or illegitimately assimilating any position to the standards of another.Today, communities are torn apart by conflicts within and between a host of different pluralist and absolutist commitments. The possibility developed in this book-a coordination of absolute and relative truth that allows an understanding of some relativist and some absolutist positions as being fully legitimate and as capable of existing in a relation to their opposites-may contribute to perspectives for resolving these conflicts. (shrink)

This article argues that there is ultimately a very close convergence between prominent conceptions of being in mainstream Anglo‐American philosophy and mainstream postmodern Continental philosophy. One characteristic idea in Anglo‐American or analytic philosophy is that we establish what is meaningful and so what we can say about what is, by making evident the limits of sense or what simply cannot be meant. A characteristic idea in Continental philosophy of being is that being emerges through contrast and interplay with what it (...) is not, with what has no being at all and so is beyond sense. The two traditions consequently conceive being in significantly related ways. As a result, what the Continental tradition gets at with “the meaning of being as such and in general,” and how it gets at it, has much in common with what the Anglo‐American tradition gets at, and how it gets at it, by establishing “what can be meaningfully said.”. (shrink)

Sometimes Always True aims to resolve, through a re-understanding of the nature of sense, three connected problems central to philosophical thought: that genuine pluralism must make room for outlooks that exclude pluralism, that philosophy ultimately explores sense as a whole and so must in some way step outside of sense, and that our experience of the deep questions of life therefore similarly involves suspensions of sense itself.

What distinguishes philosophy is its attention to reality and sense as such, or what is traditionally called being and essence. As a result, philosophy as a way of life is, most fundamentally, not directly a matter of doing one kind of thing rather than another outside the classroom but instead of how we live with respect to our being. Enacting our being in one way rather than another inflects whatever it is we do. Consequently, even if we only study philosophy (...) in the conventional, apparently unlived way in the classroom, we are in active relation to our being and therefore fully living philosophy as a way of life. (shrink)

Fogelin’s Wittgensteinian view of deep disagreement as allowing no rational resolution has been criticized from both argumentation theoretic and epistemological perspectives. These criticisms typically do not recognize how his point applies to the very argumentative resources on which they rely. Additionally, more extremely than Fogelin himself argues, the conditions of deep disagreement make each position literally unintelligible to the other, again disallowing rational resolution. In turn, however, this failure of sense is so extreme that it partly cancels its own meaning (...) as a failure of sense. Consequently, it paradoxically opens new possibilities for sense and therefore rationally unexpected resolutions. (shrink)

The paper argues that metaphysical thought, or thought in whose context our general framework of sense is under scrutiny, involves, legitimates, and requires a variety of informal analogues of the ‘true contradictions’ supported in some paraconsistent formal logics. These are what we can call informal ‘legitimate logical inadequacies’. These paradoxical logical structures also occur in deeply pluralist contexts, where more than one, conflicting general framework for sense is relevant. The paper argues further that these legitimate logical inadequacies are real or (...) inherent in sense itself rather than conventional, shows how they can feature in argumentative practice in these metaphysical and pluralist contexts, and discusses some of their implications for metaphysical truth and for philosophical inquiry and disagreement. (shrink)

If we accept that at least some kinds of nonhuman animals are persons, a variety of paradoxes emerge in our ethical relations with them, involving apparently unavoidable disrespect of their personhood. We aim to show that these paradoxes are legitimate but can be illuminatingly resolved in the light of an adequate understanding of the nature of persons. Drawing on recent Western, Daoist, and Zen Buddhist thought, we argue that personhood is already paradoxical in the same way as these aspects of (...) our ethical relations with nonhuman animals, and in fact is the source of their paradoxical character. In both contexts, depth and shallowness turn out to be internal to or crucial parts of each other, with logically anomalous consequences. We try to show that the character of this paradoxical relation between depth and shallowness in the nature of personhood involves a crucial inflection in the case of nonhuman animal persons that allows us to make sense of and resolve these ethical paradoxes. (shrink)

It is a challenge in teaching early modern philosophy to balance historical faithfulness to the arguments and concerns of early modern philosophers and interpreting them as relevant to the kinds of thinking that contemporary undergraduate students find plausible. Early modern philosophy is unique, however, in applying modern scientific method directly to problems concerning nonphysical aspects of reality that our contemporary scientific thought, and with it mainstream contemporary culture, no longer find amenable in their own, independent right to reliable reasoned approaches. (...) At the same time, early modern philosophy often also takes seriously purely conceptual or logically consequential thought in the investigation of these topics, as our mainstream contemporary culture does not. This kind of thought, we argue, is distinctive of philosophy in general and appropriate to nonphysical aspects of reality. Early modern philosophy, then, offers a bridge between the kind of reasoned, objective thought our mainstream culture finds plausible and thought about nonphysical reality or, in general, the thought that characterizes philosophy. (shrink)

Abstract: This article considers how the formal structure of metaphysical thought is displayed in Oscar Wilde's Importance of Being Earnest . One frequent aim of metaphysics is to understand the world as a whole. We cannot gain such a global vantage point without separating ourselves from all the particular meanings things have for us within the world. But we start within the world, and so can only proceed on the basis of those particular meanings. Consequently we can only separate ourselves (...) from them if they work to cancel themselves in favor of the global understanding. When the separate range of meanings is established, however, it and the world it aims to understand no longer have any meaning for each other. Metaphysics therefore succeeds by establishing and canceling its relevant meaning, all at once. This self-canceling moment or process of thought constitutes a grasp of the world as a whole. It also allows different understandings of reality as a whole to recognize and so enter into dialogue with each other. The climactic moments of The Importance of Being Earnest are structured as a map of this insight-granting process of the self-cancellation of a global range of meanings. That is, they express the formal structure of metaphysical thought. (shrink)

The article proposes an analogue of conceptual change in the context of comprehensive or deep emotional change and growth, and explores some aspects of its logic in that context. This is not to reduce emotions to concepts, but to say that concepts express the sense that is already inherent in experience and reality. When emotional states change so thoroughly that their applicable concepts become completely different, they shift from one logical structure to another. At the moment or phase when one (...) conceptual structure transforms into another, two logically incompatible descriptions both apply to the same state at the same time. As a result, the correct description of this moment and its development involves conceptual confusion, non sequitur, and logical contradiction. In these contexts, the sense itself of the emotional experience and process is partly characterized by what are otherwise violations of sense. Failure of sense is part of how these experiences make sense. The article explores some of the consequences of this paradox of sense for the nature and experience of deep emotional change and for the meaning of change itself in this context. (shrink)

The article argues that there is a central problem with the concept of public philosophy, in that philosophy is partly defined by questioning reflection on its own sense, while public or popular culture characteristically relies unreflectively on its ultimate givens, and these are mutually exclusive modes of thought. The article proposes, however, that because of philosophy’s reflection on and potential questioning of its own sense it has a paradoxical structure of foundational and comprehensive conflict with itself and its own procedure, (...) and that this self-divergence allows a genuinely philosophical role for public philosophy. In the public context, acknowledged failure to understand beyond a certain point makes room for a limitation of sense that incompletely but effectively substitutes for the properly philosophical explicit and questioning reflection on the nature of sense as such and on the possibility that even what we do understand about the relevant issues fails to have sense. (shrink)

We want to propose a conception of wisdom with a view to exploring what insights it can give us into some basic dimensions of teaching in contemporary higher education. We hope to show that this conception allows us, on the one hand, to see some crucial inadequacies of existing approaches to critical thinking, multiculturalism, and global awareness or internationalism. On the other hand, we believe that it also gives us some insight into the existentially or spiritually meaningful dimensions of learning. (...) In this way, it bridges the most contemporary and practical foci of teaching and its most fundamental and timeless concerns. In the later part of the paper, we shall explore some of the characteristics of this conception further through the teachings of some of the longstanding wisdom traditions, including what they say about teaching itself. (shrink)

Paradox and the Possibility of Knowledge argues that psychoanalytic theory has certain mostly unnoticed features that bring out, with unusual clarity, a logic that is true of conceptual thought generally. This logic is paradoxical in that it is deliberately and productively self-canceling. The general relevance of this logic to conceptual thought and to theory offers a solution to some fundamental epistemological problems. First, it allows a solution to the problem of the ultimate circularity or infinite regress of knowledge, by showing (...) how the circle or regress eliminates itself in a variety of successful knowledge-grounding ways. Second, it offers some resulting insights into issues involving politically troublesome dimensions of knowledge, specifically into the procedure of ethical political dialogue. The book is written in the contexts of both Anglo-American philosophy and Continental or European philosophy. The argument is largely Wittgensteinian, and at the same time proceeds through detailed reference to Freud's and Lacan's work. On the way it addresses theory construction in general, including the claims of phenomenology and deconstruction. (shrink)

The paper proposes with Davidson that the talk of metaontology is literally meaningless, but with Wittgenstein that it is so in a way that grants a unique type of insight. More specifically, it argues both that Davidson’s arguments have a cogency that is hard to dismiss, and also that, since his own arguments are metaontological, they are self-referential, and consequently in turn undermine their own meaning as well. The paper argues further that metaontological statements cannot be avoided. Consequently, this kind (...) of statement constitutes an unavoidable self-referential paradox that means what it also excludes as capable of meaning. The result is a reinstatement of the meaning of ontological insight and in fact, the paper argues, a deep enrichment and also a particularly cogent justification of it. In addition, the logical peculiarity of the paradox involved has further useful consequences for the outcome of this justification, including a mutually illuminating commonality with some versions of metaethics. (shrink)

The paper argues that dreams consist partly in an awareness or experience of the conceptual fabric of our existence. Since what we mean by reality is intimately tied to the concepts given in our experience, dreams are therefore also partly an awareness of the fabric of what we mean by being itself and in general, that is, by objective as well as subjective reality. Further, the paper argues that this characteristic of dreams accounts for several other, more specific aspects of (...) dreams and their possible interpretation, and that it allows us to see how these aspects are related to each other. These more specific aspects are the peculiar types of conceptual or logical relations and transitions that occur within dreams, dreams’ distinctive feeling texture, and some dimensions of the grounds and nature of suitable methods of interpreting dreams. (shrink)

Philosophy often at least implicitly includes and depends on a logical structure which is also that of jokes. This is the case when philosophy involves questioning or establishing concepts in their own right, and when it involves the kinds of metaphysics which ask about reality and the world as a whole or as such. Taking this humour-like structure into account in presenting philosophy helps, among other things, to lay open part of the character of philosophy itself, to underscore the radical (...) self-perspective that is constitutive of philosophy, and to contextualise the often confusing experience of coming to grips with an unfamiliar philosophical framework. (shrink)

The paper tries to show that when the deepest or foundational aspects of truth are at issue, both consequentially logical argument and rhetoric that aims to establish truth or justified conviction must engage with the being, or the irreplaceable particularity, of its audience’s members and also that of the arguer, what we refer to in ordinary language as who the person is. Beyond the existing discussion of existential rhetoric, the paper argues that this engagement with being is necessary to establish (...) not only truth that directly concerns or turns on the arguer’s and audience’s being, but also truth or justification about fundamental aspects of things and issues in general. Further, the address of being requires us to suspend both our own and our addressees’ familiar conceptual frameworks in order to allow being to emerge in its own terms. As a result, in contrast with our usual understanding of argumentation, the rhetorician’s initial aim and procedure will be to achieve a genuine suspension of conviction and even of the appropriate concepts under which to proceed, and so to produce a fundamental confusion. The paper then outlines some consequences for rhetoric and reasoning and also the structure of the process of working with this fundamental confusion. (shrink)

Metaphysics, morals and science -- The classics : value -- The neo-classics : utility -- The Keynesian revolution -- Development and under-development -- What are the rules of the game?

"Speciesism: 'A failure, in attitude or practice, to accord any nonhuman being equal consideration and respect'"--From the book's cover.

Three claims about essential properties are frequently advanced in recent discussions: (1) a property belongs essentially to a thing only if that thing would cease to exist without that property, (2) an essential property is explanatory, And (3) an essential property is such that it must belong to everything to which it belongs. I argue that the "only if" in (1) cannot be changed to "if and only if" and (1) needs to be supplemented by (2), And that (2) is (...) an indispensable feature of aristotle's view of essential properties and that it casts doubt on (3), Although (2) is usually assumed to provide a reason for (3). (shrink)

_A new, definitive translation of Heidegger's most important work._.

Standard accounts on the nature of the firm are highly dependent on explanations by Coase, coupled with inputs from agency theory and shareholder theory. This paper carries out their critique in light of personalist and common good postulates. It shows how personalist and common good principles create a framework that not only accommodates business ethics better but also affords a more compelling understanding of business as a whole.

A psychoanalytic and philosophical exploration of sublimation as a key term in Jacques Lacan's theories of ethics and feminine sexuality.

This paper examines how in the ‘Critique of teleological judgment’ Kant characterized the concept of natural purpose in relation to and in distinction from the concepts of nature and the concept of purpose he had developed in his other critical writings. Kant maintained that neither the principles of mechanical science nor the pure concepts of the understanding through which we determine experience in general provide adequate conceptualizations of the unique capacities of organisms. He also held that although the concept of (...) natural purpose was derived through reflection upon an analogy to human purposive activity in artistic production and moral action, it articulates a unique notion of intrinsic purposiveness. Kant restricted his critical reflections on organisms to phenomena that can be given to us in experience, criticizing speculations on their first origins or final purpose. But I argue that he held that the concept of natural purpose is a product of the reflecting power of judgment, rather than an empirical concept, and represents only the relation of things to our power of judgment. Yet it is necessary for the identification of organisms as organized and self-organizing, and as subject to unique norms and causal relations between parts and whole. (shrink)

Most evolutionary analyses of animal communication suggest that low-cost signals can evolve only when both the signaller and the recipient rank outcomes in the same order. When there is a conflict of interest between sender and receiver, honest signals must be costly. However, recent work suggests that low-cost signals can be evolutionarily stable, even when the sender and the receiver rank outcomes in different orders, as long as the interest in achieving coordination is sufficiently great. In this paper, we extend (...) this body of work by analysing a game theory model that shows that low-cost signals can evolve when there are conflicts of interest and no interest in coordination, as long as individuals interact repeatedly. We also present an empirical example indicating that female rhesus macaques, Macaca mulatta, use honest, low-cost, vocal signals to facilitate interactions when conflicts of interest exist. (shrink)