We describe here recent work on the molecular genetics of mitosis in the filamentous fungus Aspergillus nidulans. Aspergillus is one of three simple eukaryotes with powerful genetic systems that have been used to analyze mitosis. The modern molecular biological techniques available with this organism have made it possible to use mutations to identify genes and proteins that play an important role in mitosis. Three Aspergillus genes that affect mitosis are described. One gene, nimA, is specifically expressed late in the cell (...) cycle and codes for a putative protein kinase that induces mitosis, even in cells blocked in S‐phase. The second gene, bimG, codes for a putative phosphatase that interacts functionally with the nimA kinase. The third gene, bimE, codes for a protein that suppresses mitosis during interphase, apparently by keeping nimA turned off. None of these genes appear to be similar to any of the genes affecting mitosis that have been characterized in other eukaryotes, but rather appear to be elements of a system that prevents mitosis from occurring during interphase. (shrink)

he Kansas Board of Education voted 6 to 4 to remove evolution, and the Big Bang theory as well, from the state's science curriculum. In so doing, the board transported its jurisdiction to a never-never land where a Dorothy of the new millennium might exclaim, "They still call it Kansas, but I don't think we're in the real world anymore." The new standards do not forbid the teaching of evolution, but the subject will no longer be included in statewide (...) tests for evaluating students—a virtual guarantee, given the realities of education, that this central concept of biology will be diluted or eliminated, thus reducing courses to something like chemistry without the periodic table, or American history without Lincoln. (shrink)

Dorothy Emmet, in two books, one of which was based on extensive personal contact with Robert Merton and Columbia sociology, provides the closest thing we have to an authorized philosophical defense of Merton. It features a deflationary account of functionalism which dispenses with the idea of general teleological ends. What it replaces it with is an account of “structures” that have various consequences and that are maintained because, on Emmet’s account, of the mutual reinforcement of motives produced by the (...) structure. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Approaches to Teaching Spenser’s “Faerie Queene”Patricia B. PhillippyApproaches to Teaching Spenser’s “Faerie Queene,” edited by David Lee Miller and Alexander Dunlop; ix & 207 pp. New York: Modern Language Association of America, 1994, $37.50.In many respects, the teaching of Spenser’s Faerie Queene is an experience that most completely encapsulates both the challenges and the rewards of introducing students to the literature of the early modern period. As a (...) work whose length, complex narratives, substantial cast of characters, and polyvocal allegories are often daunting to undergraduates, Spenser’s epic can easily appear as a riddle to be solved rather than a work to be appreciated, let alone enjoyed. Too frequently the constraints of the syllabus and the resistance of students result in a one-dimensional rendering of the text, which permits students to feel that they have “learned something” about Spenser, and about literature generally, by seeing simple, point-by-point allegorizations (Archimago as the Pope, Duessa as Catholicism) as the work’s whole meaning. However, if these difficulties can be surmounted, few other works can equal the great opportunities available in The Faerie Queene to enrich students’ understanding of Elizabethan aesthetic, ethical, social, and political climates, and, perhaps more significantly, to impress upon them the fact that literature, as the most self-conscious of written works, seeks to elicit a multiplicity of meanings from its readers. Thus the task of critical reading appropriately moves toward expansiveness rather than inclusiveness, toward calling forth a plethora of meanings rather than eliminating all but the one “right” reading.Valuable help in overcoming the problems posed by Spenser’s work in the classroom is found in Approaches to Teaching Spenser’s “Faerie Queene.” The collection includes six essays that suggest various strategies for introducing the text to students, and nine essays devoted to more advanced study of the poem. The majority of essays in the former group concentrate on Book 1, and negotiate the practical difficulties of incorporating The Faerie Queene into undergraduate survey courses by suggesting methods to help students to bridge the gap between the work’s cultural context and their own, while also stressing the need to appreciate the text’s distinctiveness.The “special topics” essays treat individual books and themes within a variety of methodological frameworks and in light of cultural touchstones, such as the Renaissance association of painting and poetry (aided by the volume’s eight illustrations), Elizabethan colonial and imperial attitudes about Ireland, and early modern treatises and conduct books describing women’s character. A “Materials” section includes a descriptive bibliography of texts for classroom use and for students’ assigned readings, a wonderfully inclusive bibliography describing editions, reference works, background reading, and critical interpretations for the instructor’s use, and an outline of aids to teaching, such as portraits, films, and music. Even the experienced teacher of Spenser will find this a useful summary of the available materials. [End Page 278]While rooted in practical pedagogy, the essays in this collection also, for the most part, offer provocative comments on Spenser’s poem that are of scholarly interest beyond the classroom as well. Julia M. Walker’s discussion of Britomart alongside Elizabethan portraiture and Dorothy Stephens’ reading of the “feminine” in Book 4 are abridgments of longer articles from Modern Philology and ELH, respectively, and Theresa M. Krier’s provocative comments on the gendering of Spenserian symbol and allegory point toward her work in progress. Overall, the collection recommends numerous innovative techniques to energize and enliven one’s teaching of the poem and to enhance students’ experiences of it. While teachers’ awareness of the demographics and dynamics of their own students may preclude the adoption of specific approaches suggested in this volume, its essays dramatically illustrate the need to avoid reductive readings of The Faerie Queene and, at the same time, offer worthwhile guidance to prevent students from wandering endlessly through the woods of semiotic indeterminacy, error, and despair.Patricia B. PhillippyTexas A&M UniversityCopyright © 1996 The Johns Hopkins University Press... (shrink)

An examination of verbal hallucinations and thought insertion as examples of "alienated self-consciousness.".

Recently, several philosophers have challenged the view that evolutionary theory is usefully understood by way of an analogy with Newtonian mechanics. Instead, they argue that evolutionary theory is merely a statistical theory. According to this alternate approach, natural selection and random genetic drift are not even causes, much less forces. I argue that, properly understood, the Newtonian analogy is unproblematic and illuminating. I defend the view that selection and drift are causes in part by attending to a pair of important (...) distinctions—that between process and product and that between natural selection and fitness. (shrink)

The norms of simplicity, convenience, unfussiness, and self-control guide Diogenes the Cynic, Zeno of Citium, Chrysippus, Seneca, Musonius Rufus, Epictetus, and Marcus Aurelius in approaching food. These norms generate the precept that meat and dainties are luxuries, so Stoics should eschew them. Considerations of justice, environmental harm, anthropogenic global climate change, sustainability, food security, feminism, harm to animals, personal health, and public health lead contemporary Stoics to condemn the meat industrial complex, debunk carnism, and select low input, plant-based foods.

An overview of the ancient philosophers and their philosophical system (divided into the fields of logic, physics, and ethics) comprising the living, organic, enduring, and evolving body of interrelated ideas identifiable as the Stoic perspective.

Hilary Kornblith argues that many traditional philosophical accounts involve problematic views of reflection (understood as second-order mental states). According to Kornblith, reflection does not add reliability, which makes it unfit to underlie a separate form of knowledge. We show that a broader understanding of reflection, encompassing Type 2 processes, working memory, and episodic long-term memory, can provide philosophy with elucidating input that a restricted view misses. We further argue that reflection in fact often does add reliability, through generalizability, flexibility, and (...) creativity that is helpful in newly encountered situations, even if the restricted sense of both reflection and knowledge is accepted. And so, a division of knowledge into one reflexive (animal) form and one reflective form remains a plausible, and possibly fruitful, option. (shrink)

One of the most difficult problems facing anyone who would discuss Professor Carl Hempel's thesis about explanation is the following: which of the many objections that have been made are actually relevant to the thesis? Professor Hempel has claimed that several of these objections are not relevant at all. In order to evaluate such replies, let me first state what I take to be the three claims which constitute Professor Hempel's thesis.His first claim is that all adequate scientific explanations possess (...) a certain property:... all scientific explanations and their everyday counterparts claim or presuppose at least implicitly the deductive or inductive subsumability of whatever is to be explained under general laws or theoretical principles. (shrink)

Responding to the climate crisis requires social and economic innovation—because climate change is a symptom of patriarchal capitalist systems that are concentrating—rather than distributing—wealth and power. Despite the need for social and economic innovation, technological innovation continues to be prioritized in climate policy and climate investments. This paper reviews the dangers of technological optimism in climate policy by exploring its links to patriarchal systems and masculinity. The disproportionate focus on science and technology emerges from and reinforces “climate isolationism,” a term (...) that I use to refer to the common framing of climate change as an isolated discrete, scientific problem in need of technological solutions. This framing stems from assumptions of patriarchal white-male conceptions of privilege and power that evolve from a colonizing and controlling mindset. Masculine technological optimism is dangerous because it is exclusive, it minimizes the need for social change and social innovation, and it is ineffective in catalyzing inclusive societal transformation. This paper argues that embracing feminist, antiracist values is necessary for transformative climate policies, economic justice, and climate justice. (shrink)

I show that in Epictetus’ view (1) the wise man genuinely loves (στέργειv) and is affectionate (φιλόστoργoς) to his family and friends; (2) only the Stoic wise man is, properly speaking, capable of loving—that is, he alone actually has the power to love; and (3) the Stoic wise man loves in a robustly rational way which excludes passionate, sexual, ‘erotic’ love (’έρως). In condemning all ’έρως as objectionable πάθoς Epictetus stands with Cicero and with the other Roman Stoics, Seneca and (...) Musonius Rufus, and against the Greeks of the early Stoa. Epictetus’ conception of love excludes erotic passion because of its intrinsic excessiveness and uncontrollableness, which inevitably endanger mental serenity, but includes and emphasizes the soberly rational, purely positive joy of interpersonal affiliation. Epictetus’ account of how the Stoic Sage loves is, I think, more consistent and less problematic than that of the Greek Stoics. (shrink)

The ancient Stoics believed that virtue is the only true good and as such both necessary and sufficient for happiness. Accordingly, they classified food as among the things that are neither good nor bad but "indifferent." These "indifferents" included health, illness, wealth, poverty, good and bad reputation, life, death, pleasure, and pain. How one deals with having or lacking these things reflects one’s virtue or vice and thus determines one’s happiness or misery. So, while the Stoics held that food in (...) itself contributes nothing to a person’s happiness, how one obtains, prepares, and serves it, and both what and how one eats, all reveal a person’s character as good or bad. Thus, understanding the purpose of food, the necessity of frugality, and the virtue of temperance are all important in Stoicism. This paper traces the ethical views on food from Zeno of Citium and Chrysippus to Seneca, Musonius Rufus, Epictetus, and Marcus Aurelius. They agree that the wise and temperate know that simple, inexpensive foods in moderate amounts produced locally are easy to get and prepare, healthy for the body, and good for the mind. Thus, Stoicism dictates frugality of diet and the rejection of ambitious eating, gluttony, luxuries, delicacies, and gustatory extravagance. Some Stoics favor vegetarianism. All Stoics think it wise to limit eating and drinking to strict bodily need and to eradicate all food anxieties. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Commentary on “Free Will in the Light of Neuropsychiatry”G. Lynn Stephens (bio)A necessary condition of our having free will is that we initiate some of our actions by our own will or decision. Spence argues that, in light of certain empirical findings, we can accept that willing causes action, only if we acknowledge that willing is a non-conscious phenomenon. “If the notion of free will is retained... it (...) will be a free will which is essentially non-conscious.... [A] conscious free will (in the sense of consciousness initiating action) is incompatible with the evidence....” I shall argue that Spence’s conclusion depends upon a highly questionable understanding of what it is for a decision to be conscious.The evidence to which Spence refers above comes from experimental studies by Libet. This work suggests that, at least for simple motor performances, we become aware of willing the action only after the act has been initiated. This raises the possibility that our subjective experience of willing an action generally follows rather than precedes initiation of the relevant act and, hence, does not cause that action.What does all this entail concerning the causal efficacy of willing or deciding? Spence carefully refrains from drawing the conclusion that decisions never cause actions. Rather he concludes that “conscious decisions do not cause acts.... “Our decision or freedom is illusory (if by these terms we mean conscious phenomena).” We can continue to maintain that our decisions sometimes initiate actions, but only provided that we regard our decisions as non-conscious.In order to evaluate the claim that conscious decisions do not cause actions, we need to distinguish two questions: (1) Does my decision, of which I am conscious, cause me to do A? and (2) Does my being conscious of my decision cause me to do A?We might answer (1) in the affirmative, but (2) in the negative. That is, it might be true that my decision to do A caused me to do A and that I was conscious of that decision, but false that my being conscious of my decision caused me to do A. Indeed, we might suppose that, although my decision caused me to do A, I did not become conscious of that decision until after I had done A. How could this be? Suppose that my subjective experience of deciding to do A results from an (internal) perceptual process and that this process takes time. In that case it is possible that, having decided to do A, it requires more time for me to become conscious of that decision than is required for the decision to initiate my doing A. By the time I become aware of my decision, I have already done what I decided to do.The evidence Spence offers is incompatible with the hypothesis that the subjective experience of [End Page 97] my decision to do A causes me to do A, but quite compatible with the hypothesis that my decision to do A, of which I was conscious, caused me to do A. When he expresses his point by saying, “decisions to act arise prior to our consciousness of them,” or “The role of consciousness in volition is not that of initiator,” he is drawing the conclusion warranted by his evidence.However, he goes beyond his evidence when he says, “Thus our decision or freedom is illusory (if by these terms we mean conscious phenomena),” or “Conscious decision do not cause acts.” To justify these conclusions he needs to argue that something counts as a conscious decision only if we become conscious of it at precisely the instant at which it occurs. (Compare: Something counts as an event that we see, only if we begin to see it precisely at the instant at which it occurs.) Absent some defense of this view, a defense provided nowhere in Spence’s paper, we may continue to maintain that conscious decisions do cause actions.Related ArticlesFeature Article: Free Will in the Light of NeuropsychiatryCommentary: Commentary by FrithCommentary: Commentary by LibetCommentary: Commentary by StephensResponse: Response to the CommentariesG. Lynn Stephens G. Lynn Stephens, Ph.D., Department of Philosophy, University of Alabama... (shrink)

First, the thorny problem of locating the Midwest is treated. Second, the ancient Stoics’ understanding of nature is proposed as a fertile field of ecological wisdom. The significance of nature in Stoicism is explained. Stoic philosophers (big-S Stoics) are distinguished from stoical non-philosophers (small-s stoics). Nature’s lessons for living a good Stoic life are drawn. Are such lessons too theoretical to provide practical guidance? This worry is addressed by examining the examples of Cincinnatus and Cato the Elder—ancient Romans lauded for (...) their virtues who worked the land. They exhibited the virtues of civic responsibility, justice, self-sufficiency, parsimony, perseverance, equanimity, modesty, and respect for limits—an agrarian virtue dear to Wendell Berry. Agrarianism views rural society as superior to urban society and the independent farmer as superior to the paid worker. Reflection on the virtues of stoical Roman agrarians suggests that features of Roman Stoic agrarianism resonate with a contemporary instantiation of Stoicism in the Midwest. The main thesis is that Midwest Stoic agrarianism (MSA), guided by an array of earthy virtues, promotes agricultural practices that harmonize with nature and support living in agreement with nature, while rejecting agricultural practices contrary to nature and propelled by vice. MSA endorses, e.g., locally sourced, sustainably grown crops instead of CAFOs. MSA tackles the ecological and sociopolitical pressures confronting Midwest farmers in the Anthropocene and can fortify environmental virtue ethics beyond this region. (shrink)

We discuss how the Arab Spring is a reflection of the resiliency of the human rights regime. In order to accomplish this, we explore the extent to which the Arab Spring represents norm diffusion among Middle East and North Africa states. Specifically, we examine the cases of Tunisia, Egypt, and Bahrain and consider how economic and demographic changes created space for human rights discourse in these countries. We find that, in the case of MENA states, the Arab Spring represents significant (...) pressure from below. Access to new forms of social media allowed civil society to organize, publicize, and protest relatively efficiently. Social media expanded the potential role of individuals and created newly empowered latent human rights activists who emerged as leaders of the norm diffusion process. The resulting diffusion of human rights norms in the Arab region represents one of the most significant expansions of the human rights regime since the regime’s inception. (shrink)

The traditional view of evolutionary theory asserts that we can usefully understand natural selection, drift, mutation, migration, and the system of mating as forces that cause evolutionary change. Recently, Denis Walsh and Robert Brandon have objected to this view. Walsh argues that the traditional view faces a fatal dilemma and that the force analogy must be rejected altogether. Brandon accepts the force analogy but argues that drift, rather than the Hardy-Weinberg law, is the best candidate for a zero-force law. Here (...) I defend the traditional view against these objections. (shrink)

"Responding to the growing epidemic of academic dishonesty, this authoritative text lays the groundwork for a positive school makeover. This guide--which culled research from six high schools in Connecticut that indicated that more than 90 percent of students participate in some form of cheating during the average school year--provides teachers, school administrators, and parents with a toolkit of resources and strategies needed to engender a culture of scholastic honesty. With reproducible handouts and instruction on establishing an Academic Integrity Committee, this (...) unique resource provides a plan and policies that support a climate of honesty and hard work. A CD-ROM with copies of each handout and additional references is also included"-- Provided by publisher. (shrink)

Stephens and Grahamset themselves an apparently modest task, to understand why people who experience alien voices and inserted thoughts do not believe that they themselves are the source of these experiences. However, it soon becomes clear that there are many connected issues here. In eight short chapters, they address the phenomenology and ontology of consciousness, the phenomenology of alien voices, inserted thoughts, obsessive-compulsive thoughts and feelings, and other cases of unusual experience often associated with psychopathology, including brief discussion of (...) multiple personality disorder. They survey some of the main empirical explanations of the phenomenology, set out the shortcomings of these theories, and end by proposing their own schematic account. (shrink)

The Roman imperial Stoics were familiar with exile. This paper argues that the Stoics’ view of being a refugee differed sharply from their view of what is owed to refugees. A Stoic adopts the perspective of a cosmopolitēs, a “citizen of the world,” a rational being everywhere at home in the universe. Virtue can be cultivated and practiced in any locale, so being a refugee is an “indifferent” that poses no obstacle to happiness. Other people are our fellow cosmic citizens, (...) however, regardless of their language, race, ethnicity, customs, or country of origin. Our natural affinity and shared sociability with all people require us to help refugees and embrace them as welcome neighbors. Failure to do so violates our common reason, justice, and the gods’ cosmic law. (shrink)

Biologists rely extensively on the iterated Prisoner's Dilemma game to model reciprocal altruism. After examining the informal conditions necessary for reciprocal altruism, I argue that formal games besides the standard iterated Prisoner's Dilemma meet these conditions. One alternate representation, the modified Prisoner's Dilemma game, removes a standard but unnecessary condition; the other game is what I call a Cook's Dilemma. We should explore these new models of reciprocal altruism because they predict different stability characteristics for various strategies; for instance, I (...) show that strategies such as Tit-for-Tat have different stability dynamics in these alternate models. (shrink)

We defend two theses: (1) Knowledge how and knowledge that are two distinct forms of knowledge, and; (2) Stanley-style intellectualism is neuro-psychologically implausible. Our naturalistic argument for the distinction between knowledge how and knowledge that is based on a consideration of the nature of slips and basic activities. We further argue that Stanley’s brand of intellectualism has certain ontological consequences that go against modern cognitive neuroscience and psychology. We tie up our line of thought by showing that input from cognitive (...) neuroscience and psychology, on multiple levels of analysis, cohere in supporting the distinction between two separate forms of knowledge. The upshot is a neuro-psychologically plausible understanding of knowledge. (shrink)