Widespread preservation of fossilized biomolecules in many fossil animals has recently been reported in six studies, based on Raman microspectroscopy. Here, we show that the putative Raman signatures of organic compounds in these fossils are actually instrumental artefacts resulting from intense background luminescence. Raman spectroscopy is based on the detection of photons scattered inelastically by matter upon its interaction with a laser beam. For many natural materials, this interaction also generates a luminescence signal that is often orders of magnitude more (...) intense than the light produced by Raman scattering. Such luminescence, coupled with the transmission properties of the spectrometer, induced quasi‐periodic ripples in the measured spectra that have been incorrectly interpreted as Raman signatures of organic molecules. Although several analytical strategies have been developed to overcome this common issue, Raman microspectroscopy as used in the studies questioned here cannot be used to identify fossil biomolecules. (shrink)

Simone Weil (1909-1943), philosophe reconnue, engagée, mystique, ne laisse personne indifférent. Son année d'enseignement à Bourges (octobre 1935-juin 1936) est une année charnière, un moment de répit dans une courte vie mouvementée. Elle y réfléchit et y médite. Professeur de philosophie, elle a laissé une forte impression sur ses jeunes élèves du lycée de jeunes filles de Bourges. Ce sont ses cours, retrouvés grâce à deux anciennes élèves, que vous lirez dans cet ouvrage.

The emotions are at the centre of our lives and, for better or worse, imbue them with much of their significance. The philosophical problems stirred up by the existence of the emotions, over which many great philosophers of the past have laboured, revolve around attempts to understand what this significance amounts to. Are emotions feelings, thoughts, or experiences? If they are experiences, what are they experiences of? Are emotions rational? In what sense do emotions give meaning to what surrounds us? (...) -/- The Emotions: A Philosophical Introduction introduces and explores these questions in a clear and accessible way. The authors discuss the following key topics: -/- the diversity and unity of the emotions the relations between emotion, belief and desire the nature of values the relations between emotions and perceptions emotions viewed as evaluative attitudes the link between emotions and evaluative knowledge the nature of moods, sentiments, and character traits. -/- Including chapter summaries and guides to further reading, The Emotions: A Philosophical Introduction is an ideal starting point for any philosopher or student studying the emotions. It will also be of interest to those in related disciplines such as psychology and the social sciences. (shrink)

The safety conception of knowledge holds that a belief constitutes knowledge iff relevantly similar beliefs—its epistemic counterparts—are true. It promises an instructive account of why certain general principles of knowledge hold. We focus on two such principles that anyone should endorse: the closure principle that knowledge is downward closed under competent conjunction elimination, and the counter-closure principle that knowledge is upward closed under competent conjunction introduction. We argue that anyone endorsing the former must also endorse the latter on pains of (...) an unacceptable form of bootstrapping. We devise new formal models to identify necessary and sufficient conditions for these principles to hold on conceptions that construe knowledge in terms of true counterparts. These conditions state that counterparts of premise and conclusion beliefs are coordinated in certain ways whenever these beliefs stand in the relevant inferential relations. We show that the safety conception faces insuperable problems vindicating these coordination principles, because its epistemic counterpart relation is symmetric. We conclude that it thus proves unable to account for minimal closure properties of knowledge. More generally, our formal results establish parameters within which any conception must operate that construes knowledge in terms of true counterparts. (shrink)

In this paper, we develop a fresh understanding of the sense in which emotions are evaluations. We argue that we should not follow mainstream accounts in locating the emotion–value connection at the level of content and that we should instead locate it at the level of attitudes or modes. We begin by explaining the contrast between content and attitude, a contrast in the light of which we review the leading contemporary accounts of the emotions. We next offer reasons to think (...) that these accounts face substantial problems since they locate the link emotions bear to values at the level of content. This provides the incentive to pursue an alternative approach according to which emotions qualify as evaluations because they are specific types of attitudes, an approach we substantiate by appealing to felt bodily stances. We conclude by considering two reasons why this approach may be resisted; they respectively pertain to the alleged impossibility of drawing the attitude–content contrast in the case of the emotions and to the suspicion that so doing raises qualia-related worries. (shrink)

One puzzle concerning highly idealized models is whether they explain. Some suggest they provide so-called ‘how-possibly explanations’. However, this raises an important question about the nature of how-possibly explanations, namely what distinguishes them from ‘normal’, or how-actually, explanations? I provide an account of how-possibly explanations that clarifies their nature in the context of solving the puzzle of model-based explanation. I argue that the modal notions of actuality and possibility provide the relevant dividing lines between how-possibly and how-actually explanations. Whereas how-possibly (...) explanations establish claims of possible explanations, how-actually explanations establish claims of actual ones. Models, in turn, simply provide evidence for these claims. (shrink)

According to the fitting attitude (FA) analysis of value concepts, to conceive of an object as having a given value is to conceive of it as being such that a certain evaluative attitude taken towards it would be fitting. Among the challenges that this analysis has to face, two are especially pressing. The first is a psychological challenge: the FA analysis must call upon attitudes that shed light on our value concepts while not presupposing the mastery of these concepts. The (...) second challenge is normative: the FA analysis must account for the fittingness of the relevant attitudes in terms of a kind of normativity intimately related to these attitudes, but again without presupposing the mastery of the relevant value concepts. In this paper, we show that real progress is possible if we pay close attention to the nature of the attitudes recruited by the analysis. More specifically, we claim that an FA analysis that appeals to emotions conceived as evaluative attitudes — as opposed to, for instance, evaluative judgements or evaluative perceptions — has the best prospects of meeting the two challenges and of putting the FA analysis on a strong footing. (shrink)

The safety conception of knowledge holds that a belief constitutes knowledge iff relevantly similar beliefs—its epistemic counterparts—are true. It promises an instructive account of why certain general principles of knowledge hold. We focus on two such principles that anyone should endorse: the closure principle that knowledge is downward closed under competent conjunction elimination, and the counter-closure principle that knowledge is upward closed under competent conjunction introduction. We argue that anyone endorsing the former must also endorse the latter on pains of (...) an unacceptable form of bootstrapping. We devise new formal models to identify necessary and sufficient conditions for these principles to hold on conceptions that construe knowledge in terms of true counterparts. These conditions state that counterparts of premise and conclusion beliefs are coordinated in certain ways whenever these beliefs stand in the relevant inferential relations. We show that the safety conception faces insuperable problems vindicating these coordination principles, because its epistemic counterpart relation is symmetric. We conclude that it thus proves unable to account for minimal closure properties of knowledge. More generally, our formal results establish parameters within which any conception must operate that construes knowledge in terms of true counterparts. (shrink)

In this article, I side with those who argue that the debate about the definition of “disease” should be reoriented from the question “what is disease” to the question of what it should be. However, I ground my argument on the rejection of the naturalist approach to define disease and the adoption of a normativist approach, according to which the concept of disease is normative and value-laden. Based on this normativist approach, I defend two main theses: (1) that conceptual analysis (...) is not the right method to define disease and that conceptual engineering should be the preferred method and (2) that the method of conceptual engineering should be implemented following the principles of Alexandrova’s account of social objectivity in the context of the definition of disease. (shrink)

The ethics of safe sex in the gay community has, for many years, been focused on debates surrounding the responsibility regarding the use of condoms to prevent HIV transmission, once the only tool available. With the development of Truvada as a pre-exposure prophylaxis for HIV, for the first time in the history of the HIV/AIDS epidemic there is the potential to significantly reduce the risk of HIV transmission during sex without the use of condoms. The introduction of PrEP necessitates a (...) renewed discussion about the politics and ethics of safe sex for men who have sex with men. We present the arguments of authors who hold radically opposite positions with regard to the ethics of condom use by gay men, but who currently both criticize the use of PrEP. We offer a critique of their arguments and advance the position that the use of PrEP, even without condoms, can be acceptable and part of a safe sex ethics framework for MSM. (shrink)

The phenomenon of species extinction raises more and more concern among ecologists facing the actual crisis of biodiversity. Scientific investigations of the causes and effects of extinction must be completed by a philosophical analysis of the concept of extinction that aims to clarify the meanings of the term ‘extinction’ and to analyse modalities, criteria and degrees of extinction. We will focus our attention on the apparent paradox of the possible ‘resurrection’ of species in the near future with the help of (...) genetic biotechnology and cloning techniques. The ontological background of the extinction concept is analysed in relation to the idea of species as classes. We will also show that there is no simple analogy between death and species extinction, and develop a conceptualist and dualistic system of supra-individual entities , supported by an instrumentalist approach to genetic manipulations which transform species into interactive kinds, which can go extinct and be recreated. (shrink)

How does shame differ from guilt? Empirical psychology has recently offered distinct and seemingly incompatible answers to this question. This article brings together four prominent answers into a cohesive whole. These are that (a) shame differs from guilt in being a social emotion; (b) shame, in contrast to guilt, affects the whole self; (c) shame is linked with ideals, whereas guilt concerns prohibitions and (d) shame is oriented towards the self, guilt towards others. After presenting the relevant empirical evidence, we (...) defend specific interpretations of each of these answers and argue that they are related to four different dimensions of the emotions. This not only allows us to overcome the conclusion that the above criteria are either unrelated or conflicting with one another, it also allows us to tell apart what is constitutive from what is typical of them. -/- . (shrink)

Abstract The content of an emotion, unlike the content of a perception, is directly dependent on the motivational set of the subject experiencing the emotion. Given the instability of this motivational set, it might be thought that there is no sense in which emotions can be said to pick up information about the environment in the same way that perception does. Whereas it is admitted that perception tracks for us what is the case in the environment, no such tracking relation, (...) it is argued, holds between one's emotions and what they are about. It is to this worry – that the construal of the emotions as perceptions inevitably raises – that this paper tries to respond. In this paper, I suggest that when it is realized that one dimension of perception itself is directly dependent on the perceiver's perspective on her environment, then emotion, which is also essentially perspectival in this sense, bears the comparison with perception very well. After having clarified the nature and the role that perspective plays in perception, I argue that, in the case of emotions, the same perspectival role can be played by agents’ long-standing evaluative tendencies and character traits. The resulting conception of emotion as perception is then tested against possible objections. (shrink)

Is shame social? Is it superficial? Is it a morally problematic emotion? Researchers in disciplines as different as psychology, philosophy, and anthropology have thought so. But what is the nature of shame and why are claims regarding its social nature and moral standing interesting and important? Do they tell us anything worthwhile about the value of shame and its potential legal and political applications? -/- In this book, Julien Deonna, Raffaele Rodogno, and Fabrice Teroni propose an original philosophical account (...) of shame aimed at answering these questions. The book begins with a detailed examination of the evidence and arguments that are taken to support what they call the two dogmas about shame: its alleged social nature and its morally dubious character. Their analysis is conducted against the backdrop of a novel account of shame and ultimately leads to the rejection of these two dogmas. On this account, shame involves a specific form of negative evaluation that the subject takes towards herself: a verdict of incapacity with regard to values to which she is attached. One central virtue of the account resides in the subtle manner it clarifies the ways in which the subject's identity is at stake in shame, thus shedding light on many aspects of this complex emotion and allowing for a sophisticated understanding of its moral significance. -/- This philosophical account of shame engages with all the current debates on shame as they are conducted within disciplines as varied as ethics, moral, experimental, developmental and evolutionary psychology, anthropology, legal studies, feminist studies, politics and public polic. (shrink)

In this paper, my goal is to use an epistemic injustice framework to extend an existing normative analysis of over-medicalization to psychiatry and thus draw attention to overlooked injustices. Kaczmarek has developed a promising bioethical and pragmatic approach to over-medicalization, which consists of four guiding questions covering issues related to the harms and benefits of medicalization. In a nutshell, if we answer “yes” to all proposed questions, then it is a case of over-medicalization. Building on an epistemic injustice framework, I (...) will argue that Kaczmarek’s proposal lacks guidance concerning the procedures through which we are to answer the four questions, and I will import the conceptual resources of epistemic injustice to guide our thinking on these issues. This will lead me to defend more inclusive decision-making procedures regarding medicalization in the DSM. Kaczmarek’s account complemented with an epistemic injustice framework can help us achieve better forms of medicalization. I will then use a contested case of medicalization, the creation of Premenstrual Dysphoric Disorder in the DSM-5 to illustrate how the epistemic injustice framework can help to shed light on these issues and to show its relevance to distinguish good and bad forms of medicalization. (shrink)

There is a traditional conception of knowledge but it is not the Justified True Belief analysis Gettier attacked. On the traditional view, knowledge consists in having a belief that bears a discernible mark of truth. A mark of truth is a truth-entailing property: a property that only true beliefs can have. It is discernible if one can always tell that a belief has it, that is, a sufficiently attentive subject believes that a belief has it if and only if it (...) has it. Requiring a mark of truth makes the view infallibilist. Requiring it to be discernible makes the view internalist. I call the view Classical Infallibilism. (shrink)

Argumentation has been an important topic in knowledge representation, reasoning and multi-agent systems during the last twenty years. In this paper, we propose a new abstract framework where arguments are associated with a strength, namely a quantitative information which is used to determine whether an attack between arguments succeeds or not. Our Strength-based Argumentation Framework combines ideas of Preference-based and Weighted Argumentation Frameworks in an original way, which permits to define acceptability semantics sensitive to the existence of accruals between arguments. (...) The question of accruals arises in situations where several arguments defending the same position against another argument are unable to individually defeat this argument, but could do it collectively if they combine their strengths. We investigate some of the theoretical and computational properties of our new framework and semantics, and present a reasoning algorithm that is based on a translation of the problem into pseudo-boolean constraint satisfaction. This paper proposes an intuitive framework which allows strength compensations in an argumentation context where attacks may not succeed, completed by an approach which detects accruals throughout the reasoning process without requiring the elicitation of all compensatory combinations of arguments as an input. (shrink)

El artículo enfoca la crítica de la imagen dogmática en Deleuze desde un análisis retrospectivo del papel que desempeña la noción de «imagen del pensamiento» en su obra. Tras desgranar brevemente los distintos sentidos e interpretaciones con que el autor la utiliza y cerrar la introducción con la exposición del uso plenamente positivo que ese sintagma acabará adquiriendo en él, nos remontamos hasta el uso crítico y cronológicamente anterior –que no primero– de la expresión, donde la palabra «Imagen» señala esa (...) preconcepción tradicional, común a la filosofía y al buen sentido, de un pensamiento pretendidamente «natural», con el fin de arrojar una luz nueva sobre los principales ejes en torno a los cuales semejante Imagen se estructura. (shrink)

Why think that emotions are kinds of evaluations? This chapter puts forward an original account of emotions as evaluations apt to circumvent some of the chief difficulties with which alternative approaches find themselves confronted. We shall proceed by first introducing the idea that emotions are evaluations (sec. I). Next, two well-known approaches attempting to account for this idea in terms of attitudes that are in and of themselves unemotional but are alleged to become emotional when directed towards evaluative contents are (...) explored. According to the first approach, emotions are nothing but evaluative judgments. Sec. II reminds the reader of the problems associated with this idea: one of its consequences is to deprive creatures with limited cognitive capacities of any sort of partaking of emotional life. According to the second approach, which is often praised for its capacity to avoid the pitfalls facing an appeal to evaluative judgments, emotions are perception-like experiences of evaluative properties and are as such within the reach of creatures bereft of conceptual capacities. This perceptual theory is taken up in sect. III, in which we explain why it remains unsatisfactory insofar as it shares with the evaluative judgement theory the idea that what makes emotions evaluations is the specific contents that they have. On this basis, we proceed by outlining in sect. IV an alternative—the attitudinal theory of emotions. Its main point of departure from current theorizing about the emotions consists in elucidating the fact that emotions are evaluations not in terms of what they represent, but rather in terms of the sort of attitude subjects take towards what they represent. We explore here what sorts of attitudes emotions are and defend the idea that they are felt bodily attitudes. (shrink)

La série d’articles écrits par Michel Foucault sur le soulèvement iranien de 1978 a été l’objet de vives polémiques. L’analyse sérieuse et attentive d’un tel corpus montre pourtant l’intérêt qui est le sien tant sur le plan historique que conceptuel. C’est sur la notion de « spiritualité politique », certainement la plus importante des articles, que nous nous arrêterons tout particulièrement ici. Nous tenterons d’abord de comprendre pourquoi, comment et contre quoi une telle notion a émergé dans l’entreprise de description (...) de l’événement. Nous verrons ensuite les pistes et hypothèses qu’elle ouvre aujourd’hui, tant pour la recherche proprement foucaldienne que pour les recherches d’ordre théologico-politique. (shrink)

A scientific mathematical law is causal if and only if it is a process law that contains a time derivative. This is the intrinsic criterion for causal laws we propose. A process is a space-time line along which some properties are conserved or vary. A process law contains a time variable, but only process laws that contain a time derivative are causal laws. An effect is identified with what corresponds to a time derivative of some property or magnitude in a (...) process law, whereas the other terms correspond to the cause(s). According to our criterion, causes are simultaneous with their effects and causality has no temporal direction. Several examples from natural and social disciplines support the applicability of our criterion to all scientific laws. Various objections to our proposal are presented and refuted. The merits our intrinsic theory of causality vis-à-vis the Salmon–Dowe conserved quantity theory are discussed. (shrink)

Taking our lead from Solomon’s emphasis on the importance of the intentional object of emotion, we review the history of repeated attempts to make this object disappear. We adduce evidence suggesting that in the case of James and Schachter, the intentional object got lost unintentionally. By contrast, modern constructivists seem quite determined to deny the centrality of the intentional object in accounting for the occurrence of emotions. Griffiths, however, downplays the role objects have in emotion noting that these do not (...) qualify as intentional. We argue that these disappearing acts, deliberate or not, generate fruitless debate and add little to the advancement of our understanding of emotion as an adaptive mechanism to cope with events that are relevant to an organism’s life. (shrink)

ABSTRACT: Are there justified emotions? Can they justify evaluative judgements? We first explain the need for an account of justified emotions by emphasizing that emotions are states for which we have or lack reasons. We then observe that emotions are explained by their cognitive and motivational bases. Considering cognitive bases first, we argue that an emotion is justified if and only if the properties the subject is aware of constitute an instance of the relevant evaluative property. We then investigate the (...) roles of motivational bases. Finally, we argue that justified emotions are sufficient for justified evaluative judgements. View HTML Send article to KindleTo send this article to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle. Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply. Find out more about the Kindle Personal Document Service.From Justified Emotions to Justified Evaluative Judgements*Volume 51, Issue 1JULIEN A. DEONNA and FABRICE TERONI DOI: https://doi.org/10.1017/S0012217312000236Your Kindle email address Please provide your Kindle [email protected]@kindle.com Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Dropbox To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Dropbox. From Justified Emotions to Justified Evaluative Judgements*Volume 51, Issue 1JULIEN A. DEONNA and FABRICE TERONI DOI: https://doi.org/10.1017/S0012217312000236Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Google Drive To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Google Drive. From Justified Emotions to Justified Evaluative Judgements*Volume 51, Issue 1JULIEN A. DEONNA and FABRICE TERONI DOI: https://doi.org/10.1017/S0012217312000236Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Export citation Request permission. (shrink)

When spelled out properly infallibilism is a viable and even attractive view. Because it has long been summary dismissed, however, we need a guide on how to properly spell it out. The guide has to fulfil four tasks. The first two concern the nature of knowledge: to argue that infallible belief is necessary, and that it is sufficient, for knowledge. The other two concern the norm of belief: to argue that knowledge is necessary, and that it is sufficient, for justified (...) certainty. With such a guide in hand infallibilism can be evaluated on its own merits. The most controversial parts are the first and fourth. The idea that knowledge requires infallible belief is thought to be excessively sceptical. The idea that knowledge warrants certainty is thought to be excessively dogmatic. The present paper addresses the first. It argues that knowledge requires infallible belief. (shrink)

How can we use models to understand real phenomena if models misrepresent the very phenomena we seek to understand? Some accounts suggest that models may afford understanding by providing causal knowledge about phenomena via how-possibly explanations. However, general equilibrium models, for example, pose a challenge to this solution since their contribution appears to be purely mathematical results. Despite this, practitioners widely acknowledge that it improves our understanding of the world. I argue that the Arrow–Debreu model provides a mathematical how-possibly explanation (...) which establishes claims of mathematical dependence. The account developed reveals how mathematical knowledge can inform claims about the world, allow ‘what-if-things-had-been-different’ inferences, and thus improve our understanding. (shrink)

Ne serait-ce que par son titre, dont l’oxymore est d’emblée assumée (p.11) et dont les protagonistes sont associés d’une manière qui ne laisse de surprendre, l’ouvrage de Julien Boudon publié dans la collection « Les sens du droit » des éditions Dalloz, mériterait de retenir l’attention.Dans ce court opus, l’auteur entend, à travers un examen qui puise tout à la fois aux sources de l’histoire, de la philosophie, du droit, de la science politique, et qui emprunte à la fois (...) au style de la monog.. (shrink)

L'art comme empreinte revisite les fondamentaux de l'art en explorant sa nature pour définir l'art comme une empreinte. La trace d'un charbon sur un mur ou d'un pinceau sur une toile font jaillir l'oeuvre, mais explorer cette apparente banalité de l'empreinte révèle le mystère et la complexité de l'art. Rencontre entre l'homme et la matière, l'art tout comme l'empreinte est une frontière en perpétuelle mutation qui permet à l'humanité l'exploration de soi et du monde. Car si l'art est techniquement une (...) empreinte, il est aussi la projection de la personnalité de l'artiste qui en façonnant la matière se découvre toujours un peu plus, et vient aussi nourrir la culture de son temps. Son art vient en effet transformer à leur tour ceux qui le contemplent, et qui en sont changés comme la toile sous le pinceau. L'empreinte est ce qui reste quand celui qui l'a laissée a disparu, la part de l'autre en nous qui fait avancer notre humanité. Voie de connaissance et de transmission, l'empreinte est ce qui permet l'interaction et donc l'évolution, ce qui met l'art en perpétuel mouvement. Figure fondamentale de l'être, elle constitue une force de changement qui est à la base de la vie et de la beauté du monde. (shrink)

Volume 1. Égypte antique, Grèce antique, Empire romain, judaïsme, islam, Perse mazdéenne, hindouisme -- volume 2. Des débuts du christianisme à aujourd'hui.

In this paper, I argue for a new way to understand the integration of facts and values in the concept of mental disorder that has the potential to avoid the flaws of previous hybrid approaches. I import conceptual tools from the account of procedural objectivity defended by Helen Longino to resolve the controversy over the definition of mental disorder. My argument is threefold: I first sketch the history of the debate opposing objectivists and constructivists and focus on the criticisms that (...) led to the emergence of the debate. Second, I offer a reconstruction of the “Natural Function Approach” argument to make explicit an unsound assumption underlying this approach. The reconstruction will allow me to show that the NFO’s argument depends on the ideal of value-free science that I will criticize. Then I propose an alternative ideal for psychiatry: social objectivity. I argue that the concept of mental health should be seen as “socially objective” rather than value-free, moving the debate towards the social procedures by which the definition is produced rather than the normative and factual content of its definition. (shrink)

The introduction of pre-exposure prophylaxis (PrEP) for HIV has triggered critical analysis within the social sciences. For example, some have signalled how PrEP may lead to a renewed medicalisation of gay and other homosexually-active men’s sexuality. This chapter challenges some of those accounts. Adopting a public health ethics perspective, it argues that gay men should be understood as agentic in their use of PrEP, as opposed to being the passive victims of medicalisation, and that greater attention should be paid to (...) questions of pleasure in PrEP use. Applying a reproductive justice framework, the chapter argues that the worldwide inaccessibility of PrEP constitutes a more serious ethical issue than the potential problem of the medicalisation of gay men’s sexuality. (shrink)

RNA polymerase II (RNAP II) non‐coding transcription is now known to cover almost the entire eukaryotic genome, a phenomenon referred to as pervasive transcription. As a consequence, regions previously thought to be non‐transcribed are subject to the passage of RNAP II and its associated proteins for histone modification. This is the case for the nucleosome‐depleted regions (NDRs), which provide key sites of entry into the chromatin for proteins required for the initiation of coding gene transcription and DNA replication. In this (...) review, recent data on the effects of pervasive transcription through NDRs are summarized and a model is proposed to explain how RNAP II‐driven transcription is able to modify the nucleosomes flanking the NDRs, leading to nucleosome repositioning and NDR closure. Even though much of the mechanistic detail underlying these events remains to be elucidated, such a model provides a basis to explain how non‐coding transcription through NDRs can regulate the initiation of coding gene expression and DNA replication. (shrink)

Models typically have actual, existing targets. However, some models are viewed as having non-actual targets. I argue that this interpretation comes at various costs and propose an alternative that fares better along two dimensions: (1) agreement with practice and (2) ontological and epistemological parsimony. My proposal is that many of these models actually have actual targets.

For the past two decades, philosophers of religion have paid close attention to the debates on public reason taking place within the context of political philosophy. Some thinkers claim that religious arguments should play a very limited role in political discourse, as this would amount to a politically sanctioned imposition of religious beliefs on people with different religious or non-religious worldviews. Others claim that excluding religious reasons would lead to an unfair exclusion of religious citizens from democratic processes. Underlying these (...) positions is a highly problematic idea of what it means to be a religious citizen. On the one hand, religious citizens are conceptualized as highly self-reflective theologians. Others instead imagine religious citizens to be wholly incapable of such self-reflection and of distinguishing between public and non-public spheres. In my article I attempt to criticize these underlying assumptions and point towards a more nuanced conception of the religious citizen. (shrink)

From the Tin Pan Alley 32-bar form, through the cyclical forms of modal jazz, to the more recent accumulation of digital layers, beats, and breaks in Electronic Dance Music, repetition as both an aesthetic disposition and a formal property has stimulated a diverse range of genres and techniques. From the angles of musicology, psychology, sociology, and science and technology, Over and Over reassesses the complexity connected to notions of repetition in a variety of musical genres. The first edited volume on (...) repetition in 20th- and 21st-century popular music, Over and Over explores the wide-ranging forms and use of repetition - from large repetitive structures to micro repetitions - in relation to both specific and large-scale issues and contexts. The book brings together a selection of original texts by leading authors in a field that is, as yet, little explored. Aimed at both specialists and neophytes, it sheds important new light on one of the fundamental phenomena of music of our times. (shrink)

In this paper, we contrast the different ways in which the representationalist and the attitudinalist in the theory of emotions account for the fact that emotions have evaluative correctness conditions. We argue that the attitudinalist has the resources to defend her view against recent attacks from the representationalist. To this end, we elaborate on the idea that emotional attitudes have a rich profile and explain how it supports the claim that these attitudes generate the wished-for evaluative correctness conditions. Our argument (...) rests on the idea that emotional attitudes manifest a sensitivity to evaluative evidence and that this sensitivity secures the kind of normativity we expect of the emotions. We bring our discussion to a close by assessing whether the psychological underpinnings of this sensitivity to evaluative evidence are such as to threaten the foundation of attitudinalism: the idea that emotions do not represent values. Given the available models of how we might access values prior to emotional experience, we conclude that the attitudinalist is still in the game. (shrink)

For Hannah Arendt, authority is the shape educational responsibility assumes. In our time, authority in Arendt’s sense is under pressure. The figure of Greta Thunberg shows the failure of adult generations, taken collectively, to take responsibility for the world and present and future generations of newcomers. However, in reflecting on Arendt’s use of authority, we argue that her account of authority also requires amendments. Arendt’s situating of educational authority in-between past and future adequately captures its temporal dimension. We make explicit (...) another, spatial, dimension: authority in-between world and earth. Arendt’s neglect of the material earth also has implications for the relational dimension of authority. Arendt’s authority depends on a dichotomy between the private and the public sphere. This is problematic. First, we agree with Arendt’s feminist critics that the personal can be made into the site of the political. Second, we point once more to Thunberg, the child, taking the public stage, thereby contesting the division between public and private. In response, we situate the relational dimension of authority in-between private and public. The three dimensions of educational authority taken together imply that it is situated in-between domains that cannot be reduced to each other or taken as absolutes: past and future, world and earth, and the private and public sphere. This brings us to our concept of ambiguous authority, which expresses the Arendtian nature of our reflections and the ways in which we seek to renew her original insights on educational authority. (shrink)

In this article, the authors examine and debate the categories of emotions, moods, temperaments, character traits and sentiments. They define them and offer an account of the relations that exist among the phenomena they cover. They argue that, whereas ascribing character traits and sentiments (dispositions) is to ascribe a specific coherence and stability to the emotions (episodes) the subject is likely to feel, ascribing temperaments (dispositions) is to ascribe a certain stability to the subject's moods (episodes). The rationale for this (...) distinction, the authors claim, lies in the fact that, whereas appeal to character traits or sentiments in explanation is tantamount to making sense of a given behaviour in terms of an individual's specific evaluative perspective - as embodied in this individual's emotional profile - appeal to temperaments makes sense of it independently of any such evaluative perspective. (shrink)