Molecular motor proteins, fueled by energy from ATP hydrolysis, move along actin filaments or microtubules, performing work in the cell. The kinesin microtubule motors transport vesicles or organelles, assemble bipolar spindles or depolymerize microtubules, functioning in basic cellular processes. The mechanism by which motor proteins convert energy from ATP hydrolysis into work is likely to differ in basic ways from man‐made machines. Several mechanical elements of the kinesin motors have now been tentatively identified, permitting researchers to begin to decipher the (...) mechanism of motor function. The force‐producing conformational changes of the motor and the means by which they are amplified are probably different for the plus‐ and minus‐end kinesin motors. BioEssays 25:1212–1219, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

The cellular processes of transport, division and, possibly, early development all involve microtubule‐based motors. Recent work shows that, unexpectedly, many of these cellular functions are carried out by different types of kinesin and kinesin‐related motor proteins. The kinesin proteins are a large and rapidly growing family of microtubule‐motor proteins that share a 340‐amino‐acid motor domain. Phylogenetic analysis of the conserved motor domains groups the kinesin proteins into a number of subfamilies, the members of which exhibit a common molecular organization and (...) related functions. The kinesin proteins that belong to different subfamilies differ in their rates and polarity of movement along microtubules, and probably in the particles/organelles that they transport. The kinesins arose early in eukaryotic evolution and gene duplication has allowed functional specialization to occur, resulting in a surprisingly large number of different classes of these proteins adapted for intracellular transport of vesicles and organelles, and for assembly and force generation in the meiotic and mitotic spindles. (shrink)

A framework for understanding the complex movements of mitosis and meiosis has been provided by the recent discovery of microtubule motor proteins, required for the proper distribution of chromosomes or the structural integrity of the mitotic or meiotic spindle. Although overall features of mitosis and meiosis are often assumed to be similar in mechanism, it is now clear that they differ in several important aspects. These include spindle structure and assembly, and timing of chromosome segregation to opposite poles. Here we (...) review progress in the functional characterization of several newly identified microtubule motor proteins, emphasizing their possible roles in spindle structure and function. (shrink)

While feminist epistemologists have made important contributions to the deconstruction of the traditional representationalist model, some elements of the Cartesian legacy remain. For example, relativism continues to play a role in the underdetermination thesis used by Longino and Keller. Both argue that because scientific theories are underdetermined by evidence, theory choice must be relative to interpretive frameworks. Utilizing Davidson's philosophy of language, I offer a nonrepresentationalist alternative to suggest how relativism can be more fully avoided.

In lieu of an abstract, here is a brief excerpt of the content:Moral Distress for the Physician AssistantSharyn L. KurtzMy morning rounds as an inpatient medical oncology physician assistant began as usual. I arrived at the hospital early to receive 7 a.m. sign out from the covering resident. The overnight report began favorably. All patients remained stable. Even my patient, whom I will call Mrs. Walker,* had a quiet night. However, given her tenuous admission presentation, including altered mental status, hypercalcemia (...) (high levels of calcium in the blood), atrial fibrillation with rapid ventricular response (irregular, rapid heart function), widespread metastatic lung cancer, and recent neurosurgery to stabilize her spine, I decided to prioritize Mrs. Walker’s morning evaluation.Examining her medical chart proved reassuring. Her tachycardia (rapid heart rate) had been better controlled over the past two days. Her hypercalcemia had been treated, such that she was no longer somnolent. In fact, she was now arousable, conversant, and able to offer some input regarding her healthcare wishes. However, because she was experiencing intermittent delirium, her husband continued to act as her primary medical decision–maker.As her health care proxy, Mr. Walker had experienced conflict with the medical team during his wife’s prior hospital admission. However, even though Mr. Walker lived greater than 45 minutes from the hospital and was not able to visit regularly, he and I spoke daily by phone, which allowed me the opportunity to offer regular medical updates. Mr. Walker felt overwhelmed with his wife’s condition, but he was comfortable with the care the medical team had provided thus far. He was encouraged by the small improvements we had noted since her hospital admission five days prior.Mr. Walker stated on hospital admission that he wished for DNR/I orders to be placed, since this cohered with his wife’s previously stated wishes. However, he still wanted “everything else done” in terms of treating his wife’s medical conditions, including treatment of her atrial fibrillation, pain, and electrolyte anomalies. Most of all, he hoped Mrs. Walker would soon have increased mobility, which he felt would grant his wife the best quality of life possible. He was adamant that “being active” was what Mrs. Walker wished for, and that she had never wanted to be confined to bed.Mr. Walker’s requests seemed reasonable. Although Mrs. Walker’s lung cancer was widespread, and although many on the medical team felt she would not improve to the point where palliative chemotherapy could be considered, [End Page E13] she had stabilized. Her recent spine surgery had been successful, and she was healing adequately. The neurosurgeons had cleared Mrs. Walker for increased activity out of bed as soon as she could be fitted with a lumbar brace. The pain and palliative care specialists felt that Mrs. Walker’s residual back pain and delirium could be well managed with oral medications.Prior to my entering Mrs. Walker’s room to begin her physical evaluation, I was met by her seasoned nurse, whom I will call Amy. “Sharyn,” Amy warned, “Mrs. Walker’s heart rate is 150 and she is complaining of chest pain.” I entered Mrs. Walker’s room, and she was notably uncomfortable, grasping her chest. The monitor showed that Mrs. Walker’s heart rate was in fact in the 150’s. She was pale, short of breath, and wheezing. “Mrs. Walker,” I asked, “how severe is your chest pain on a scale from 1 to 10?” Mrs. Walker replied, “Nine.” I asked Amy to obtain an EKG, to provide oxygen, and to administer an IV medication that would slow Mrs. Walker’s heart rate. I stepped out of the room to place the computer orders, and I paged my attending physician to let him know about Mrs. Walker’s change in status. After hearing the update, my attending physician, whom I will call Dr. Clark, stated that he agreed with all of my treatment decisions thus far. He was on his way into the hospital. I planned out my next steps with him on the phone and returned to the patient’s room.The monitor gave evidence that Mrs. Walker’s heart rate was improving. Mrs. Walker reported that her pain was now “4 out of... (shrink)

Clough shows how inadequate empirical philosophy is in creating real change in the sciences. Instead, she supports a more pragmatic approach based on the work of Richard Rorty and Donald Davidson. This work encourages Clough's fellow feminists to refocus their critiques and discard their philosophical debates about epistemology.

Feminist theorists have shown that knowledge is embodied in ways that make a difference in science. Intemann properly endorses feminist standpoint theory over Longino’s empiricism, insofar as the former better addresses embodiment. I argue that a pragmatist analysis further improves standpoint theory: Pragmatism avoids the radical subjectivity that otherwise leaves us unable to account for our ability to share scientific knowledge across bodies of different kinds; and it allows us to argue for the inclusion, not just of the knowledge produced (...) from marginalised bodies, but of the marginalised themselves. (shrink)

Racist beliefs express value judgments. According to an influential view, value judgments are subjective, and not amenable to rational adjudication. In contrast, we argue that the value judgments expressed in, for example, racist beliefs, are false and objectively so. Our account combines a naturalized, philosophical account of meaning inspired by Donald Davidson, with a prominent social-psychological theory of values pioneered by the social-psychologist Milton Rokeach. We use this interdisciplinary approach to show that, just as with beliefs expressing descriptive judgments, beliefs (...) expressing value judgments have empirical content, or can be inferentially linked to beliefs that do; the truth or falsity of that content can be objectively assigned; and that assignment is amenable to rational assessment. While versions of this objective view of value judgments have been defended by moral realists of various metaphysical stripes, our argument has the virtue of appealing, instead, to accounts that are as naturalistically informed as possible. And, unlike the influential subjective view of value judgments, and racist beliefs more particularly, our arguments are better able to account for instances where rational, persuasive strategies have been effective in reducing the ubiquity of racism in American culture. (shrink)

Fact/value holism has become commonplace in philosophy of science, especially in feminist literature. However, that facts are bearers of empirical content, while values are not, remains a firmly-held distinction. I support a more thorough-going holism: both facts and values can function as empirical claims, related in a seamless, semantic web. I address a counterexample from Kourany where facts and values seem importantly discontinuous, namely, the simultaneous support by the Nazis of scientifically sound cancer research and morally unsound political policies. I (...) conclude that even by the criteria available at the time, Nazi cancer research was empirically weak, and the weaknesses in their research are continuous with their moral failures in just the ways predicted by the holism I support. (shrink)

Despite increasing numbers of women lawyers, gender segregation within the legal profession in the United States continues. The present article examines interorganizational differences in the employment of 34 men and 34 women lawyers in 12 in-house legal departments that varied by size and industry in corporations located in the northeast United States. There were differences among the firms with respect to the number, position, and salary of men and women lawyers. The findings suggest that women in-house counsel do not enter (...) the same type of practice or organizations, obtain the same positions, or earn the same salaries as men. The differential employment patterns, the article concludes, stem largely from organizational contingencies, such as a firm's market position, perceived needs, the kinds of rewards and training offered, and recruitment strategies. It also suggests that men's and women's differential location in the labor pool results not from their own career choices but from employer's hiring and work-allocation decisions that provide them with different experiences and expertise, which in turn constrain future employment options. (shrink)

In assessing the appropriateness of a scientific community's research effort, Solomon considers a number of "decision vectors," divided into the empirical and non-empirical. Value judgments get sorted as non-empirical vectors. By way of contrast, I introduce Anderson's discussion of the evidential role of value judgments. Like Anderson, I argue that value judgments are empirical in the relevant sense. I argue further that Solomon's decision matrix needs to be reconceptualized: the distinction should not be between the empirical vs. non-empirical, but between (...) the relevant vs. irrelevant. Whether particular value judgments are relevant or not is an empirical question, to be decided on a case-by-case basis. (shrink)

This chapter’s main topic revolves around Davidson’s account of radical interpretation and the concept of triangulation as a necessary feature of communication and the formation of beliefs. There are two important implications of this model of belief formation for feminists studying the effects of social location on knowledge production generally, and the production of scientific knowledge in particular. The first is Davidson’s argument that whatever there is to the meaning of any of our beliefs must be available from the radical (...) interpreter’s external, third-person perspective. The second important implication of triangulation is that Davidson’s model is a holistic one that shows that there is no substantive difference in the triangulation process by which we form beliefs concerning basic descriptive features of the world and beliefs concerning evaluative features of the world. (shrink)

Recent cases in the United States and Australia have catapulted surrogacy into the forefront of debates and public policy regarding new procreative technologies, even though gestating and birthing a baby for another woman does not necessarily involve artificial insemination or in vitro fertilization. Feminists have condemned commercial surrogacy because it borders on baby selling and exploits women. Similar criticism has appeared in the mass media, but these forums, as well as the medical profession, have considered noncommercial surrogacy as more acceptable (...) because of the absence of monetary exchange. Using two cases of surrogacy, this article argues that the distinction between commercial and altruistic surrogacy is socially constructed rather than based on self-evident or intrinsic differences. Both types of surrogacy involve the application of pervasive gender norms specifying that women's motivations to have children should be based on emotion, selflessness, and caring, not on self-interest, financial incentives, or pragmatism. Applying these norms renders commercial surrogacy deviant, but altruistic arrangements more acceptable. However, the article's central argument is that both types of agreement can entail exploitation, the denial of the birth mother's rights, and the severe reduction of her autonomy. (shrink)

Within the New Zealand curriculum, hauora has been co-opted as an underlying and interdependent concept at the heart of the learning area of health and physical education. Hauora is identified as a Māori philosophy of well-being, advocating a Māori world view of hauora. Contemporary understandings of hauora as a Māori philosophy of health are constructed within dominant English-medium curriculum discourses. At first glance the juxtaposition of ‘hauora’ with ‘well-being’, and hauora being defined as ‘a Māori philosophy of health’ seems like (...) an opportunity to promote an indigenous perspective of health into English-medium curriculum, but the philosophical questions of what knowledge is valued, why we should teach it, and its worth of what is taught for human well-being, remain fraught. The notion of hauora is much richer than the word ‘health’ allows. I explore some issues associated with the equivalence between hauora and health, and some of the potential nuances of hauora in light of a counter-colonial Māori philosophy of holism. I invite the reader to consider the terms ‘whakapapa’ and ‘wairua’ in light of a proposed metaphysics. I show that the terms—and the objects they point to—share a relationship with each other and that recognition of that interdependence are necessary to their well-being. (shrink)

Within the New Zealand curriculum, hauora has been co-opted as an underlying and interdependent concept at the heart of the learning area of health and physical education. Hauora is identified as a Māori philosophy of well-being, advocating a Māori world view of hauora. Contemporary understandings of hauora as a Māori philosophy of health are constructed within dominant English-medium curriculum discourses. At first glance the juxtaposition of ‘hauora’ with ‘well-being’, and hauora being defined as ‘a Māori philosophy of health’ seems like (...) an opportunity to promote an indigenous perspective of health into English-medium curriculum, but the philosophical questions of what knowledge is valued, why we should teach it, and its worth of what is taught for human well-being, remain fraught. The notion of hauora is much richer than the word ‘health’ allows. I explore some issues associated with the equivalence between hauora and health, and some of the potential nuances of hauora in light of a counter-colonial Māori philosophy of holism. I invite the reader to consider the terms ‘whakapapa’ and ‘wairua’ in light of a proposed metaphysics. I show that the terms—and the objects they point to—share a relationship with each other and that recognition of that interdependence are necessary to their well-being. (shrink)

In a recent essay — “How Can Feminist Theories of Evidence Assist Clinical Reasoning and Decision-making?” — Maya Goldenberg discusses criticisms of evidence-based medicine (or EBM) (Goldenberg 2013). She is particularly interested in those criticisms that make use of an epistemic appeal to the underdetermination of theory by evidence...

Though the overall numbers of women judges remain small, higher proportions of women have been appointed to many lower courts in common law, and particularly in civil law, countries. This paper investigates whether the experiences of judging and judicial work differ among women and men magistrates in Australia’s lower courts. The particular focus is satisfaction with their work as judges. In so doing, it helps build up a picture of the extent of the gendered nature of the judiciary as an (...) occupation. Measures of overall job satisfaction identify few gender differences; more refined measures highlight areas of divergence between men and women magistrates, suggesting gendered experiences of judicial work which result from particular characteristics of the occupation, as presently constituted, rather than the nature of judging itself. (shrink)

Empirical legal research into courts and adjudication starts with a formal model of trial courts and the nature of adjudication. This article discusses empirical legal research on trial courts and adjudication and divides them into three dimensions of analysis, macro, meso, and micro, to frame the discussion of empirical legal studies into courts and adjudication, the various methods researchers use, and significant findings. Empirical research may be theoretical, pragmatic or policy oriented. A large body of research approaches the study of (...) courts and adjudication from an organizational perspective, looking at court structures and how they affect daily operation. Examining trial court judges' approaches to their work, including adjudication, using survey research has also been undertaken in non-English speaking jurisdictions. Each type of research design has specific strengths and advantages, as well as limitations, but each contributes to advancing knowledge about the nature, role, and reality of trial courts and adjudication. (shrink)

I have argued that political values are beliefs informed, more or less well, by the evidence of experience and that, where relevant and well-supported by evidence, the inclusion of political values in scientific theorizing can increase the objectivity of research. The position I endorse has been called the “values-as-evidence” approach. In this essay I respond to three kinds of resistance to this approach, using examples of feminist political values. Solomon questions whether values are beliefs that can be tested, Alcoff argues (...) that even if our values are beliefs that can be tested, testing them might not be desirable because doing so assigns these important values a contingency that weakens their normative force, and Yap argues that the approach is too idealistic in its articulation of the role of evidence in our political deliberations. In response, I discuss the ways that values can be tested, I analyze the evidential strength of feminist values in science, and I argue that the evidence-based nature of these values is neither a weakness nor an idealization. Problems with political values affecting science properly concern the dogmatic ways that evaluative beliefs are sometimes held—a problem that arises with dogmatism toward descriptive beliefs as well. I conclude that scientists, as with the rest of us, ought to adopt a pragmatically-inclined appreciation of the fallible, inductive process by which we gather evidence in support of any of our beliefs, whether they are described as evaluative or descriptive. (shrink)

The dominant image of judicial authority is emotional detachment; however, judicial work involves emotion. This presents a challenge for researchers to investigate emotions where they are disavowed. Two projects, one in Australia and another in Sweden, use multiple sociological research methods to study judicial experience, expression, and management of emotion. In both projects, observational research examines judicial officers’ display of emotion in court, while interviews investigate judicial emotional experiences. Surveys in Australia identify emotions judicial officers generally find important in their (...) work; in Sweden, shadowing allows researchers to investigate individual judicial emotion experiences and expression. Evaluating the different methods used demonstrates the limitations and effectiveness of particular research designs, the value of multiple methods and the challenges for researching emotion. (shrink)

The hygiene hypothesis offers an explanation for the correlation, well-established in the industrialized nations of North and West, between increased hygiene and sanitation, and increased rates of asthma and allergies. Recent studies have added to the scope of the hypothesis, showing a link between decreased exposure to certain bacteria and parasitic worms, and increased rates of depression and intestinal auto- immune disorders, respectively. What remains less often discussed in the research on these links is that women have higher rates than (...) men of asthma and allergies, as well as many auto-immune disorders, and also depression. The current paper introduces a feminist understanding of gender socialization to the epidemiological and immunological picture. That standards of cleanliness are generally higher for girls than boys, especially under the age of five when children are more likely to be under close adult supervision, is a robust phenomenon in industrialized nations, and some research points to a cross- cultural pattern. I conclude that, insofar as the hygiene hypothesis successfully identifies standards of hygiene and sanitation as mediators of immune health, then attention to the relevant patterns of gender socialization is important. The review also makes clear that adding a feminist analysis of gender socialization to the hygiene hypothesis helps explain variation in morbidity rates not addressed by other sources and responds to a number of outstanding puzzles in current research. Alternative explanations for the sex differences in the relevant morbidity rates are also discussed (e.g., the effects of estrogens). Finally, new sources of evidence for the hygiene hypothesis are suggested in the form of cross-cultural and other natural experiments. (shrink)

In this review article we describe the current scope, methods, and contents of medical ethics education in medical schools in Western English speaking countries (mainly the United Kingdom, the United States, and Australia). We assess the strengths and weaknesses of current medical ethics curricula, and students’ levels of satisfaction with different teaching approaches and their reported difficulties in learning medical ethics concepts and applying them in clinical practice. We identify three main challenges for medical ethics education: counteracting the bad effects (...) of the “hidden curriculum,” teaching students how to apply ethical knowledge and critical thinking to real cases in clinical practice, and shaping future doctors’ right character through ethics education. We suggest ways in which these challenges could be addressed. On the basis of this analysis, we propose practical guidelines for designing, implementing, teaching, and assessing a medical ethics program within a four-year medical course. (shrink)

In lieu of an abstract here is the first paragraph: -/- I mean the subtitle of my essay both as praise for the clarity with which Elizabeth Anderson writes about what is at stake in debates about values in science, and as a promise to outline an even more direct route to the heart of the matter. I begin with a quick review of the steps in Anderson’s argument that seem necessary and, indeed, laudable, followed by a brief discussion of (...) those steps in her argument that we might fruitfully skip. The hope is that we will arrive at roughly the same location but with a firmer foothold. (shrink)

The works of the later Wittgenstein resonate with aspects of the pragmatist tradition in American philosophy. Davidson’s work is similarly informed. We argue that because of their association with the pragmatist tradition, their work can be put to use by philosophers interested in social justice issues, including, for example, feminism, and critical race theory. Philosophers concerned with social justice continue to struggle between the extremes of an untenable foundationalism and a radical relativism. Given their holistic understanding of knowledge, meaning and (...) communication, the work of Wittgenstein and Davidson is particularly suited to dissolving the foundationalist/relativist dichotomy. We explore how this and other features of their work facilitates philosophy for social change. (shrink)

An anencephalic infant, who came to be known as Baby K, was born at Fairfax Hospial in Falls Church, Virginia, on October 13, 1992. From, the moment of birth and repeatedly thereafter, the baby's mother insisted that aggressive measures be pursued, including cardiopulmonary resuscitation and ventilator support, to keep the baby alive as long as possible. The physicians complied. However, following the baby's second admission for respiratory failure, the hospital sought declaratory relief from the court permitting it to forgo emergency (...) life support on the grounds that “a requirement to provide respiratory assistance would exceed the prevailing standard of medical care,” and that “because any treatment of their condition is futile, the prevailing standard of medical care for infants with anencephaly is to provide warmth, nutrition, and hydration.” The United States Court of Appeals for the Fourth Circuit ruled in favor of the baby's mother, citing the federal Emergency Medical Treatment and Active Labor Act , which contained no “standard of care” exception to the requirement to provide “treatment necessary to prevent the material deterioration of the individual's condition.” An appeal to the United States Supreme Court was rejected. The baby died some two and one-half years later of cardiac arrest during her sixth visit to the emergency department of Fairfax Hospital for respiratory failure. (shrink)

Peace literacy shows why public philosophy and activism for peace and justice are better together while providing a practical framework designed to make the collaboration stronger and more effective. In this chapter, the authors begin with an overview of peace literacy and then show how it operates as an effective lens through which to read the strengths of various approaches to public philosophy and activism for peace and justice, from the eighteenth to the twentieth centuries and into the contemporary period. (...) Then, they turn to the development of peace literacy themes as we find them in the work of philosophers dedicated to publicly engaged activism for peace and justice, especially in American movements for the abolition of chattel slavery, anti‐war and nonviolence, and civil rights. (shrink)

Malcolm Acock attempts to show that three widely accepted “solutions” to the philosophical problem of theory choice between the ordinary account of the age of the universe, and “Russell's hypothesis” that the world sprang into existence five minutes ago, are unsatisfactory. In the following paper we shall attempt to show why “Russell's hypothesis” is defective as a cosmological explanation of the age of the universe.

Journal of Human Values, Volume 28, Issue 1, Page 29-43, January 2022. The COVID-19 crisis has revealed a need for rethinking approaches to education and livelihoods. Education in its present dispensation does not provide equitable access to children from marginalized segments of the population. It also suffers from deficits in the areas of social and emotional skills, over-emphasis on the three Rs, language used as a medium of instruction, and excessive competition for scoring marks, among others. There is very low (...) uptake of vocational education. The National Education Policy 2020 tries to address some of these issues and plans on closer integration of vocational education with the school framework. High unemployment rates of educated youth, along with underemployment due to skill mismatch, show poor school-to-work transition and underscore the importance of TVET for youth in the future. Skill already exists in the economy in informal knowledge systems which are largely undocumented and thus not acknowledged in the formal system. These need to be combined with Western-centric knowledge systems so that the imbalance between formally educated/trained workers and informally trained workers is redressed. There is also a need to bring back the joy of learning, as Tagore’s experimentation with education has demonstrated. (shrink)

Compiled by an archaeologist and philosopher of science, Science at the Frontiers: Perspectives on the History and Philosophy of Science supplements current literature in the history and philosophy of science with essays approaching the traditional problems of the field from new perspectives and highlighting disciplines usually overlooked by the canon. William H. Krieger brings together scientists from a number of disciplines to answer these questions and more in a volume appropriate for both students and academics in the field.

L’idea che vi sia una netta dicotomia tra fatti e valori è uno dei dogmi dell’empirismo. Secondo questa concezione, i giudizi fattuali, in quanto verificabili o falsificabili empiricamente, riguardano le aree di razionalità «pura» e omogenea e sono ancorati naturalisticamente al mondo. Gli enunciati di valore, invece, sarebbero da relegare nella sfera di ciò che è semplicemente «soggettivo», emotivo, irrazionale. Questo assunto, che ha dominato per molto tempo le scienze e la filosofia, è stato messo in dubbio dai pragmatisti e (...) da alcuni dei più influenti pensatori contemporanei, che, intervenendo al dibattito sull’oggettività dell’etica, hanno mostrato come la presunta eterogeneità tra giudizi descrittivi e giudizi valutativi sia ormai insostenibile. Sulla scia della prospettiva inaugurata da questi pensatori, gli autori di questo libro mostrano come la dicotomia fatto/valore abbia corrotto il nostro pensiero, impedendoci di rivolgere l’attenzione alle intersezioni, le sinergie e le relazioni che esistono tra processi cognitivi e coefficienti valutativi, tra scienza e etica. Con saggi di S. Clough, D. Copp, D. Davidson, G. Marchetti, H. Putnam, R. A. Putnam B. Stroud, K. A. Taylor, V. Walsh. (shrink)

In this paper we study the variety \(\textsf{WL}\) of bounded distributive lattices endowed with an implication, called weak Lewis distributive lattices. This variety corresponds to the algebraic semantics of the \(\{\vee,\wedge,\Rightarrow,\bot,\top \}\) -fragment of the arithmetical base preservativity logic \(\mathsf {iP^{-}}\). The variety \(\textsf{WL}\) properly contains the variety of bounded distributive lattices with strict implication, also known as weak Heyting algebras. We introduce the notion of WL-frame and we prove a representation theorem for WL-lattices by means of WL-frames. We extended (...) this representation to a topological duality by means of Priestley spaces endowed with a special neighbourhood relation between points and closed upsets of the space. These results are applied in order to give a representation and a topological duality for the variety of weak Heyting–Lewis algebras, i.e., for the algebraic semantics of the arithmetical base preservativity logic \(\textsf{iP}^{-}\). (shrink)

The book from which these sections are excerpted is concerned with the prospects for assimilating the study of human intelligence and its products to the natural sciences through the investigation of cognitive structures, understood as systems of rules and representations that can be regarded as These mental structui′es serve as the vehicles for the exercise of various capacities. They develop in the mind on the basis of an innate endowment that permits the growth of rich and highly articulated structures along (...) an intrinsically determined course under the triggering and partially shaping effect of experience, which fixes parameters in an intricate system of predetermined form. It is argued that the mind is modular in character, with a diversity of cognitive structures, each with its specific properties arid principles. Knowledge of language, of the behavior of objects, and much else crucially involves these mental structures, and is thus not characterizable in terms of capacities, dispositions, or practical abilities, nor is it necessarily grounded in experience in the standard sense of this term. (shrink)

Though many philosophers of mind have taken an interest in the great developments in the brain sciences, the interest is seldom reciprocated by scientists, who frequently ignore the contributions philosophers have made to our understanding of the mind and brain. In a rare collaboration, a world famous brain scientist and an eminent philosopher have joined forces in an effort to understand how our brain interacts with the world. Does the brain behave as a calculator, combining sensory data before deciding how (...) to act? Or does it behave as an emulator endowed with innate models of the world, which it corrects according to the results of experiences obtained by the senses? The two authors come from very different backgrounds - the philosopher Jean-Luc Petit belongs to the philosophical tradition of Husserlian phenomenology. Alain Berthoz has long been interested in the physiology of action (movement, posture, decision-making, perception, etc.). Drawing on cutting-edge research from the cognitive sciences, the authors have produced a highly original volume showing how phenomenology and physiology can interact to further our understanding of the brain and the mind. (shrink)

The main objective o f this descriptive paper is to present the general notion of translation between logical systems as studied by the GTAL research group, as well as its main results, questions, problems and indagations. Logical systems here are defined in the most general sense, as sets endowed with consequence relations; translations between logical systems are characterized as maps which preserve consequence relations (that is, as continuous functions between those sets). In this sense, logics together with translations form a (...) bicomplete category of which topological spaces with topological continuous functions constitute a full subcategory. We also describe other uses of translations in providing new semantics for non-classical logics and in investigating duality between them. An important subclass of translations, the conservative translations, which strongly preserve consequence relations, is introduced and studied. Some specific new examples of translations involving modal logics, many-valued logics, para- consistent logics, intuitionistic and classical logics are also described. (shrink)

I first present a conception of the relata involved in the dialogic relation. I and thou are persons endowed with a first-person perspective and concepts through which they can represent themselves as distinct of anyone or anything else. Then I briefly discuss the epistemology and metaphysics of persons as agents. I adopt a realist view against any epistemological projects denying (or feigning to deny) the existence of the second person. Then I expose the complementary view of the secondperson perspective, which (...) close the gap between the first- and third-person perspectives. I expose some historical milestones recognizing the importance of the second-person perspective in dialogue. After an examination of the conditions for the use of mental terms, I propose an analysis of dialogue in sequences of illocutionary acts, stressing the importance of perlocutionary plans. Any dialogue worthy of the name involves mutual understanding. In my reconstruction, I use distinctions proposed by Burge, Dummett and Austin. There are degrees of understanding in dialogue. In the highest degree, we have a real “meeting of minds.” Finally, a genuine dialogue is different from a fictional dialogue. I also suggest, taking side with Descartes, that the interaction man-machine cannot be classified as genuine dialogue. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Status of the Person in the Humanism of Giovanni Gentile" A. ROBERT CAPONIGRI THE HUMANISMOf Giovanni Gentile has gradually come to be recognized as one of the major speculative achievements of our time. The great strength and appeal of this position lie chiefly in the manner in which it meets the exigencies of the modem analysis of man and human existence while retaining the basic classical insights of (...) western thought. It achieves a synthesis which possesses at once historical, speculative, and cultural value and which rectifies many of the unilateral analyses so much in evidence. At the same time, serious limitations have been alleged to mar the Gentilean view of man. The most important of these allegations concerns the notion most intimately associated with the humanism of the west: the person. Strangely, it has been charged that the humanism of Gentile not only fails to develop an adequate concept of the person but directly involves the diminution and constriction of this concept as it has developed historically and influenced the western view of man. His, it is asserted, is a humanism without the person, which is but a small remove from the paradoxical assertion that it is a humanism without man? In many ways this charge is most perplexing. Were it correct, it would certainly have the limiting and constrictive effects his critics have pointed out. The real perplexity resides, however, not in spelling out the probable consequences of the allegation, but in determining how it might ever have arisen and gained such credence and championship. The fact is that nothing could be further from Gentile's intention and (what is more important) more alien to the burden of his text than the least diminution of the person. On the contrary, the person constitutes the central and pivotal notion of the entire structure of Gentilean humanism. The constructive effort of his thought is directed principally to the elaboration and validation of this * This paper was read before the Thirteenth International Congress of Philosophy, Mexico City (September, 1963), but has not been included in the Proceedings of the Congress. 1 M. F. Sclacca, II XX Secolo (1947), Vol. I, pp. 400 ft.; R. Holmes, The Idealism of Giovanni Gentile (1957), passim; H. S. Harris, The Social Philosophy of Giovanni Gentile (1960), passim. [6q 62 HISTORY OF PHILOSOPHY concept of the person. Once established, this concept becomes the cardinal principle upon which all his subsequent explorations and assertions in the areas of art, ethics, social and political theory, and education hinge. Consequently, it seems of utmost importance, for the comprehension of his thought and of its place in the total prospect of contemporary philosophy, to place in clear relief the basic lineaments of the concept of the person as it emerges from the critical stages of Gentile's thought as well as the role it plays in all subsequent constructive efforts. Formation of the Concept of the Person in Gentile's Thought To understand the emergence of the concept of the person in actualism, it is necessary to determine clearly Gentile's basic point of departure. This is established firmly in the history of philosophy: a fact which corroborates Harris's perception that Gentile's thought is essentially an historical enterprise? One of Gentile's chief and most sustained fields of effort is the history of philosophy and his work in this area served a double purpose. The first was the properly historical and critical work of establishing an interpretation of the course of the history of western philosophy; s the second was to locate his own thought in the context of the history of philosophy as thus established and thus to endow it with a firm scientific and "public" character, to assign it a "public" basis. This public basis was the achievement of western philosophy which his analysis had recognized as solid and beyond cavil. This achievement, he reasoned, must constitute the point of departure of any further relevant speculation. Gentile took the philosophical position of Hegel as representing this indubitable achievement of western thought in its most salient features. This statement must be correctly understood to be of any help and importance in approaching his thought. Gentile did not... (shrink)

A graph-theoretic account of logics is explored based on the general notion of m-graph (that is, a graph where each edge can have a finite sequence of nodes as source). Signatures, interpretation structures and deduction systems are seen as m-graphs. After defining a category freely generated by a m-graph, formulas and expressions in general can be seen as morphisms. Moreover, derivations involving rule instantiation are also morphisms. Soundness and completeness theorems are proved. As a consequence of the generality of the (...) approach our results apply to very different logics encompassing, among others, substructural logics as well as logics with nondeterministic semantics, and subsume all logics endowed with an algebraic semantics. (shrink)

A Hilbert algebra with supremum is a Hilbert algebra where the associated order is a join-semilattice. This class of algebras is a variety and was studied in Celani and Montangie . In this paper we shall introduce and study the variety of $${H_{\Diamond}^{\vee}}$$ H ◊ ∨ -algebras, which are Hilbert algebras with supremum endowed with a modal operator $${\Diamond}$$ ◊ . We give a topological representation for these algebras using the topological spectral-like representation for Hilbert algebras with supremum given in (...) Celani and Montangie . We will consider some particular varieties of $${H_{\Diamond}^{\vee}}$$ H ◊ ∨ -algebras. These varieties are the algebraic counterpart of extensions of the implicative fragment of the intuitionistic modal logic $${\mathbf{IntK}_{\Diamond}}$$ IntK ◊ . We also determine the congruences of $${H_{\Diamond}^{\vee}}$$ H ◊ ∨ -algebras in terms of certain closed subsets of the associated space, and in terms of a particular class of deductive systems. These results enable us to characterize the simple and subdirectly irreducible $${H_{\Diamond}^{\vee }}$$ H ◊ ∨ -algebras. (shrink)

The introductory ode of Horace's fourth book has been given comparatively little critical attention, although it might have been expected to arouse exceptional interest, being the first-fruits of the lyricist's autumnal harvest. The neglect is due partly to the poem's deceptive simplicity but much more to the unease which it arouses in Horace's admirers: Venus does not seem the most fitting deity for the poet laureate to invoke, and moreover this is not so much an invocation as an appeal to (...) be left alone; the young man who is the subject of Horace's eulogy was hardly a person of much eminence at the time of writing, though he became prominent later and is now prosopographically well endowed; above all, there is the disturbing picture of the elderly poet testily acknowledging an amorous urge and surrendering his dignity in pederastic dreams. (shrink)

Recent research on algebraic models of _quasi-Nelson logic_ has brought new attention to a number of classes of algebras which result from enriching (subreducts of) Heyting algebras with a special modal operator, known in the literature as a _nucleus_. Among these various algebraic structures, for which we employ the umbrella term _intuitionistic modal algebras_, some have been studied since at least the 1970s, usually within the framework of topology and sheaf theory. Others may seem more exotic, for their primitive operations (...) arise from algebraic terms of the intuitionistic modal language which have not been previously considered. We shall for instance investigate the variety of _weak implicative semilattices_, whose members are (non-necessarily distributive) meet semilattices endowed with a nucleus and an implication operation which is not a relative pseudo-complement but satisfies the postulates of Celani and Jansana’s strict implication. For each of these new classes of algebras we establish a representation and a topological duality which generalize the known ones for Heyting algebras enriched with a nucleus. (shrink)

Unlike the traditional earnings tax which is based on the individual’s actual income, the endowment tax is based on the individual’s maximum potential income. The endowment tax raises a frightful prospect: an individual taxed according to her potential income as, say, a corporate lawyer might be forced to give up her preferred occupation as a philosophy professor and to work as a corporate lawyer in order to pay her taxes. Although this seems to be an impermissible intrusion on freedom, the (...) challenge is to specify why the endowment tax is impermissible in a way that does not rule out all forms of taxation. After showing why the solutions put forward by John Rawls and by Liam Murphy and Thomas Nagel fail, I provide my own solution. I claim that the endowment tax is impermissible not because it forecloses more options but because of which options it forecloses. Thus, in order to explain the impermissibility of the endowment tax, we first need to distinguish the options to which individuals have a legitimate moral claim. I suggest one way of drawing this distinction by appealing to two principles widely embraced in the philosophical literature. If my argument is right, then the income tax as it is currently implemented is also morally impermissible. (shrink)

The article traces origins of the contradiction that calls into being the polemics on the moral status of duties to close persons. Special obligations are created by the unique life narrative of an actor that makes different recipients of her actions more or less distant. Those who are less distant are “close ones.” Those who are more distant are “strangers.” The basis of this distance can be different: individual sympathy, consanguinity, belonging to cultural, territorial and political communities. Special obligations presuppose (...) that the preferential treatment of “close ones” is not only permissible but obligatory. This feature of moral duties to close persons makes moral philosophers suspicious because they are prone to endow moral requirements with two interrelated properties: universality and the high level of generality. The main reason for this is that the typical moral duty is a duty of every human being to another human being without any further qualifications. Against the background of such duties, any preference to close persons looks like the breach of moral equality and manifestation of impermissible partiality. Though, common moral beliefs persistently include special obligations in the whole system of moral duty. R. Goodin thinks that they have a priority over positive general duties and yield to negative general duties. The empirical researches of moral evaluations which reviewed in this article in general confirm this conclusion. The ethical theory cannot ignore fundamental features of common moral beliefs. That is why it is doomed to look for ways of reconciling the moral equality and impartiality with the preferential treatment of close persons embedded into special obligations. (shrink)

Though it is held that some models in science have explanatory value, there is no conclusive agreement on what provides them with this value. One common view is that models have explanatory value vis-à-vis some target systems because they are developed using an abstraction process. Though I think this is correct, I believe it is not the whole picture. In this paper, I argue that, in addition to the well-known process of abstraction understood as an omission of features or information, (...) there is also a family of abstraction processes that involve aggregation of features or information and that these processes play an important role in endowing the models they are used to build with explanatory value. After offering a taxonomy of abstraction processes involving aggregation, I show by considering in detail several models drawn from different sciences that the abstraction processes involving aggregation that are used to build these models are responsible for their having explanatory value. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The University and Democracy: A Response to “Dewey, Implementation, and Creating a Democratic Civic University”Lee A. McBride IIIira harkavy has given us much to consider. His paper, “Dewey, Implementation, and Creating a Democratic Civic University,” invites us to critically assess our democracy and the role of colleges and universities in the propagation of our democratic way of life. Harkavy suggests that universities are failing to fulfill their function, that (...) is, “to educate students to be ethical, empathetic, engaged, democratic citizens, and advance knowledge for the continuous betterment of the human condition” (50). He suggests that universities are central societal institutions in the world, and research universities are most central—“they develop new ideas and technologies, incubate businesses, serve as cultural and artistic centers, and are engines of local, national, and global economics” (50). Our universities produce our teachers and our teachers’ teachers; they shape the learning, values, and the aspirations of students (Harkavy 50). But, again, universities are not fulfilling their social function of “creating and sustaining an inclusive, just democratic society” (Harkavy 51). Harkavy boldly asserts that a revolutionary change is required in higher education if it is to fulfill its democratic function.Closed LoopI have a concern about the role of Research 1 (R1) universities in this picture. I am led to believe that R1 universities, like the University of Pennsylvania, exist in rarefied air. Penn, for example, has a ridiculous endowment—more than $20 billion. Penn apparently accepts only 9% of its applicants. The resources and demographics of R1 institutions are unlike those at state schools and small liberal arts colleges. The various canons, the faculty, and the student body at elite R1 universities have historically represented the thoughts, [End Page 76] experiences, and perplexities of well-heeled white heteronormative men. The vast majority of the faculty and students at R1 universities are predominantly of Anglo-European descent and a higher socioeconomic status. This gives me pause. If R1 universities are placed as the central engines of democratic fomenting, I worry that the faculty and students at R1 universities will direct research and social amelioration projects in particular directions and retain particular presuppositions that will buttress the continued flourishing of elite R1 universities. A closed loop. I worry that both the material and the social capital needed to (re)shape social conditions will arise only from and circulate only between those who attend elite R1 universities. I mean, Harkavy suggests that the departments, programs, and institutes at R1 universities create and sustain those knowledges and skills that produce the scholars and thoughtful people who will drive our K–12 education, who will fashion new cooperatives and entrepreneurial ventures, and who will become our community activists and political leaders. As such, the knowledge and skills to implement a more just and inclusive democracy will be disseminated from the R1 university. Harkavy also explains that it is necessary that universities strive to be democratic civic universities, sites where university folk work alongside members of the surrounding communities to address and ameliorate the problems on the ground. This “would involve significant and ongoing engagement of an institution’s comprehensive assets (academic, human, cultural, and economic) in partnership with community members to produce knowledge and educate ethical students with the ability to help create and maintain just, anti-racist, democratic societies” (Harkavy 53). The democratic civic university would then nurture a culture of democracy that exceeds mere voting practices— democracy as a way of life (Dewey 226). Prima facie, this seems like a noble goal. And yet, I still worry that those university folks who do this work will be a small representative group of people who bear particular life experiences and perhaps phenotypic markers.I would suggest that other sites outside of the R1 university (e.g., the trade union meeting, the settlement house, the church, the community garden, etc.) will need to be taken as legitimate sites of knowledge creation or legitimate sites of communication and joint activity (Collins 269). This would at least bring differing life experiences to the table; that is, it would bring differing life experiences to the fore and recognize alternative non-academic sources of insight and wisdom. These sites and alternative... (shrink)

Fibring has been shown to be useful for combining logics endowed withtruth-functional semantics. However, the techniques used so far are unableto cope with fibring of logics endowed with non-truth-functional semanticsas, for example, paraconsistent logics. The first main contribution of thepaper is the development of a suitable abstract notion of logic, that mayalso encompass systems with non-truth-functional connectives, and wherefibring can still be dealt with. Furthermore, it is shown that thisextended notion of fibring preserves completeness under certain reasonableconditions. This completeness transfer (...) result, the second main contributionof the paper, generalizes the one established in Zanardo et al. (2001) butis obtained using new techniques that explore the properties of a suitablemeta-logic (conditional equational logic) where the (possibly)non-truth-functional valuations are specified. The modal paraconsistentlogic of da Costa and Carnielli (1988) is studied in the context of this novel notionof fibring and its completeness is so established. (shrink)

The latest volume in the splendid critical edition of the Opera philosophica et theologica of William of Ockham in progress at the Franciscan Institute of St. Bonaventure University under the general editorship of Gedeon Gál, O.F.M. The project itself is something of a phenomenon in the area of critical editions of medieval Latin texts in terms of the rapidity at which quality volumes are produced at remarkably reasonable costs. Since 1967 five quarto volumes, totaling some three thousand four hundred pages, (...) have appeared. Three of these contain the first portion of Ockham’s most important theological work, the Ordinatio of his "commentary" on book 1 of the Sentences. The final portion is scheduled to appear early in 1979 as volume 4 of the Opera theologica. Volume 1 of the philosophical opera contains the monumental Summa Logicae, and volume 3 will also appear this year, thus completing with the present volume the edition of the most important of Ockham’s logical works. Editors are also assigned and are already at work on the other major non-political writings, notably the Quodlibet and commentaries on Aristotle’s Physics. Since the Opera politica Guillelmi de Ockham were published in three octavo volumes by the University of Manchester Press, we may expect to have very shortly substantially all the works of the Venerable Inceptor, thanks to the exceptional industry of a team of highly qualified researchers as well as substantial grants by the National Endowment for the Humanities and the De Rance Corporation. Two of the editors of individual works in the present volume are deceased. Father Philotheus Boehner, O.F.M., who came to the Franciscan Institute from Germany before the outbreak of World War II, first conceived of and began work on the critical edition. His text of the Tractatus de praedestinatione was first published in 1945 in Franciscan Institute Publications, Text Series No. 2 and was subsequently translated into English by M. M. Adams and N. Kretzmann in 1969. It differs little in Brown’s revision, which adds variants from the Bruges MS, unavailable to Boehner because of the war. The other posthumous edition is that of E. A. Moody. This too appeared in the aforesaid Text Series as No. 14. The present text is identical with the earlier version, but observations and suggested alternate readings by the general editor are added in footnotes. The thirty-two pages of introduction contains a wealth of information. To mention but two items: One concerns the probable reason why Ockham only incepted in theology but never served as regent master. This apparently had little or nothing to do with Lutterall’s opposition, as Chancellor of the University, to Ockham’s views and his summons later to the papal court at Avignon. It stemmed rather from the Franciscan custom of promoting those bachelors who had completed their magisterial studies to regent master on the basis of seniority. At his time a junior like Ockham could expect a wait of eight to ten years. It was during this period, beginning probably in 1321 that he began his lectures on logic, probably at the Franciscan house of studies in London where he later composed the Summa Logicae and his exposition of Aristotle’s Physics, before the summer of 1324 when he went to Avignon. Another item is the effective refutation of the authenticity views of Prantl and Anneliese Maier of the Expositiones and their relationship to the spurious and derivative Notabilia. As a final comment, we note that this second volume of the Opera philosophica contains all the works of Ockham edited by Marcus de Benevento under the title Expositio aurea et admodum utilis super artem veterem edita per Ven. Inceptorem Guilielmum de Occham, [[sic]] cum quaestionibus Alberti Parvi de Saxonia.—A.B.W. (shrink)