O livro almeja ser representativo nos principais debates contemporâneos, oferecendo uma visão panorâmica sobre o campo na atualidade e permitindo-se aprofundar em algumas discussões selecionadas.O ambiente não pode ser reduzido ao “meio ambiente”, à natureza não humana. Ele não é meramente algo que “nos envolve”, um envoltório: o ambiente somos também nós, seres humanos, histórica e culturalmente situados. Quanto aos territórios, eles se estabelecem em íntima conexão com os ambientes em suas dimensões paisagística e material, quer sejam os processos geoecológicos, (...) quer sejam as formas e as dinâmicas socialmente produzidas. Analisar os territórios significa examinar como, a cada momento, os ambientes, seus recursos e significados são disputados e viram objeto de conflitos.O público-alvo principal são os estudantes dos últimos anos da graduação, além daqueles em nível de pós-graduação, de todas as áreas que lidam com problemas e conflitos ambientais. Afora os pesquisadores iniciantes e os jovens universitários em geral, porém, podemos presumir que profissionais experientes também poderão tirar proveito do material de diversos capítulos. É razoável, por fim, nutrir a expectativa de que muito do que este livro contém possa (retro)alimentar o ativismo ambiental crítico e a prática de combater as iniquidades e as distorções que se acumulam em nossas sociedades, principalmente as muitas situações de flagrante injustiça ambiental. (shrink)

XLRI, in association with a few Tata Group companies, established the XLRI-JRD Tata Foundation in Business Ethics in 1991 to mark their long-standing commitment and contribution to business ethics in India. The foundation seeks to address this by publicly affirming the urgent need for ethics in business and the need to bring about a conducive culture in which it can thrive.

Professional skepticism is a critical component of the auditor’s skill set. Developing this component takes time for accounting students and new auditors. Rather than waiting until they have an internship or a full-time auditing position, students can begin practicing this essential skill earlier in their academic careers. The case presents students in their first undergraduate auditing course an introduction to the need for more complex thinking and professional skepticism in the auditing and forensic accounting areas. The case focuses on risk (...) assessment and critical evaluation of audit evidence, primarily through audit interviews. In addition, the case allows students to learn the value of preparation and strategy uniquely: their first attempt at the case is almost impossible to solve. (shrink)

Convenções e costumes estabelecem que a denominação galinheiro prevaleça em espaços destinados abrigar bichos de pena de variadas extrações. Este o caso do galinheiro em questão, cujo domínio, em que pese a absoluta maioria galinácea, é ostensivamente exercido por casal de perus. Caminhos se abrem quando todo enfunado, rabo imponentemente aberto em leque, o senhor peru desanda grugrulejante e majestoso a desfilar.Fato de subidíssima relevância motiva-o no momento a incorporar com frequência essa postura de maneira menos casual: madame perua está (...) chocando. (shrink)

Nestes nossos tempos gerundistas e de valores-isopores o apelo ao eufemismo e à grandiloquência torna-se palavra de ordem e progresso. Oficinas mecânicas passam a ser chamadas de centros automotivos, açougues transmutam-se em butiques de carnes e sapatarias em recuperadoras de calçados.Daí a gente olha em volta e começa igualmente a não achar mais nem barbearias nem barbeiros.Quedê, perguntamos, a Tesoura de Ouro do Carlão? Pois seu salão ganhou a neomodernosa indicação de Cabeleireiro Masculino e virou ele esteticista capilar. Bate daí (...) saudade danada – possivelmente, diria. (shrink)

Conheci Raduan num sábado entre junho ou julho de 1996. Estimo os meses e garanto o dia e o ano em razão de Menina a caminho. Amizades comuns nos levaram então a participar de festa familiar no paulistano bairro do Pacaembu. Situado em rua tranquila, o restaurado sobrado compunha-se das variadas dependências requeridas em outros tempos por famílias de classes em fase de ascensão. No piso térreo, destacava-se o espaço destinado aos convidados: a ampla sala, integrada à copa e a (...) um ajardinado terraço. Sobretudo ali as crianças da casa e de vários convidados comiam, corriam e algazarreavam. (shrink)

Alci, Miguelzinho e Lazinho trouxeram espigas de milho, as primeiras colhidas no milharal de Ivo e Sueli, amigos e vizinhos, e Rosilene colocou na panela. Mais tarde, Alci, voltou com imensa abóbora que foi logo transformada em doce e ainda será quibebe e sopa, tudo em fogão de lenha. Neste recanto do sul de Minas, descoberto há cinco anos, conseguimos construir um pequeno refúgio. Marcia, arquiteta, decidiu que a casa teria grandes janelas e portas de vidro, abrindo para a floresta, (...) para vales e montanhas e, do lado direito, para a Pico do Papagaio, um dos símbolos de Minas Gerais. (shrink)

This work presents the diverse fields of expertize, various viewpoints, ideas and rich experiences in this field. This collection stresses on importance of the perception of Gift of Life in a Pluralistic Society .

Graphical AbstractDomains can spread among proteins in a process called domain shuffling and this has been identified as one of the major mechanisms leading to the formation of new proteins throughout evolution. This process has an impact on the topology of protein-protein interaction networks as it may create new hubs and also increase interconnectivity.

Human newborns can resolve some response conflicts in order to adapt their behaviour, suggesting that the newborn has consciousness according to Morsella et al.'s framework. However, we pose a range of developmental questions regarding Morsella et al.'s account, especially concerning the role of consciousness in the development of action.

Within the perception-action framework, the underlying mechanisms of empathy and its related processes of moral behavior need to be investigated. fMRI studies have shown different frontal cortex activation patterns during automatic processing and judgment tasks when stimuli have moral content. Clinical neuropsychological studies reveal different patterns of empathic alterations after dorsolateral versus orbital frontal cortex damage, related to deficient cognitive and emotional processing. These processing streams represent different neural levels and mechanisms underlying empathy.

This paper criticizes social revolution, by focusing on the reconfiguration of the notion from an ethical point of view. It is divided in three sections: Brother’s death; Remove the sandals; Thou wilt be as many as the stars. Each section contains Levinas’s thought as the main axis. Although it is well known that Levinas does not develop a theory of revolution, it is possible to find a fruitful analysis in light of his meditations about politics and ethics.

The will is one of the three pillars of the trilogy of mind that has pervaded Western thought for millennia, the other two being affectivity and cognition (Hilgard 1980). In the past century, the concept of will was imperceptibly replaced by the cognitive-oriented behavioral qualifiers “voluntary,” “goal-directed,” “purposive,” and “executive” (Tranel et al. 1994), and has lost much of its heuristic merits, which are related to the notion of “human autonomy” (Lhermitte 1986). We view catatonia as the clinical expression of (...) impairment of the brain mechanisms that promote human will. Catatonia is to the brain systems engaged in will, as coma is to the reticular ascending systems that promote sleep and wakefulness (Plum 1991). (shrink)

BackgroundPreprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completeness of reporting, as transparency can improve the reader’s ability to independently interpret data and reproduce findings.MethodsIn this observational study, we initially compared independent samples of articles published in bioRxiv and in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed paired comparisons (...) between preprints from bioRxiv to their own peer-reviewed versions in journals.ResultsPeer-reviewed articles had, on average, higher quality of reporting than preprints, although the difference was small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in the independent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easy it was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions did not correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journal publication.ConclusionsOur results suggest that, on average, publication in a peer-reviewed journal is associated with improvement in quality of reporting. They also show that quality of reporting in preprints in the life sciences is within a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea that preprints should be considered valid scientific contributions. (shrink)

Our goal was to explore self‐care practices among men who have sex with men in the context of Mpox in Brazil. This study used qualitative research methods, including interviews and thematic analysis, to collect and analyze data from male participants across the Brazilian territory. The narratives unveil men's perspectives on self‐care, risk reduction, and health beliefs during the Mpox pandemic. Our findings highlight a multifaceted approach to self‐care among men, encompassing hygiene, physical contact management, mask usage, skin lesion vigilance, and (...) adherence to official guidelines. Men's attitudes toward sexual behaviors emphasize the importance of reducing sexual partners, practicing safe sex, and combating misinformation through accurate information dissemination. The development of these behaviors and self‐care practices can be facilitated by nurses guided by Dorothea Orem's Self‐Care Theory, supported by patient‐centered care, with strategies to address and confront the stigma associated with the disease and provide emotional support. Thus, the study underscores the pivotal role of self‐care in mitigating infection risks, especially in the context of emerging infectious diseases. It acknowledges the impact of socio‐cultural factors and healthcare policies on men's preventive measures. However, it also recognizes limitations, such as potential bias due to stigma concerns and a nonrepresentative sample. Ultimately, the research advocates for tailored education, promotion of gender equity, and healthcare empowerment to effectively manage health risks in such contexts. (shrink)

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

Information transmission from tumor cells to non‐tumor cells in the surrounding microenvironment via microvesicles is a more recently studied form of intercellular signaling that can have a marked impact on the tumor microenvironment. Tumor‐derived microvesicles (TMVs) are packed with information including signaling proteins and nucleic acids, and can be taken up by target cells, enabling paracrine signaling. While previous research has focused on how vesicles released from pathologic cells differ from normal cells, the heterogeneity that exists within the TMV population (...) itself is not fully characterized, and only beginning to be appreciated. In this review, we summarize current understanding of the biogenesis and roles of shed TMVs in the tumor microenvironment, and speculate on the consequences for tumor cell signaling in light of the hypothesis that there exists variance within the TMV population. The analysis of differential signaling upon cell‐TMV interactions provides insights into potential mechanisms of intercellular communication. (shrink)

O texto propõe uma leitura da temática da justiça na obra de J. Derrida a partir não somente da interpretação dos textos em si mas também dos contextos de seu surgimento num determinado momento histórico-filosófico de reconsideração do estatuto da racionalidade e das consequências desta reconsideração para a filosofia em geral.

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

One of the first difficulties in interpreting Hume’s epistemological writings concerns precisely the meaning of the words ‘knowledge’ and ‘belief’. In this article it is shown, initially, how, from a humean point of view, the traditional epistemic criterion to define ‘knowledge’ and ‘belief’ appears very restrictive. Hume’s theory of causal belief is then briefly reviewed in the light of epistemological naturalism of the Michael J. Costa and Louis E. Loeb. Finally, it is submitted that the examination of all these topics (...) lends support to the Hume’s naturalistic theory of justification of beliefs. (shrink)

RESUME Dans cet article, j’aborde la perspective idéaliste de la « Phénoménologie de la perception » pour montrer que, dans cet ouvrage, l’expérience du corps propre est décrite à partir de la vision du cogito. Pour expliciter cet idéalisme, j’analyse la principale voix donnée au corps au début de la pensée de Merleau-Ponty: la voix pathologique. Les troubles de Schneider rendent explicite son impuissance symbolique, et cette impuissance est vraiment l’impuissance du corps. Le sujet malade est un être soumis à (...) la normativité immédiate de la vie, raison par laquelle il peut découvrir à chaque moment la finitude et la fragilité de l’existence. J’évoque par contre les notes du cours au Collège de France, de 1954-1955, sur la passivité et les cours sur la Nature, de 1957-1958, lorsque Merleau-Ponty examine la vie et la naissance du sens à partir d’une perspective tout à fait différente. J’analyse aussi la lecture qu’il a faite du « cas Dora » pour montrer que le philosophe trouve dans l’hystérie une expérience symbolique très particulière. Cette expérience exige la compréhension de la puissance symbolique du corps propre, l’abandon de la position idéaliste et la découverte du pouvoir de l’hystérique de narrer l’expérience de l’être. ABSTRACT In this article, I approach the idealistic perspective of the “Phenomenology of Perception” to show that in that work the experience of the body is described from a vision of the cogito. To explain this idealism, I asses the main voice given to the body in the beginning of the thought of Merleau-Ponty: the pathological voice. Schneider’s disturbances make explicit its symbolic powerlessness, and that powerlessness is in fact the body’s powerlessness. The sick is a being submitted to the immediate normativity of life, reason by which he can find out at every moment the finitude and fragility of existence. On the other hand, I evoke the course notes from Collège de France, of 1954-1955, about passivity, and the courses about Nature, of 1957-1958, when Merleau-Ponty analyses life and the birth in the sense from an entirely different perspective. Also, I analyze the reading of what he to “case Dora” to show that the philosopher finds in hysteria a very particular symbolic experience. This experience requires understanding the symbolic power of the body itself, the abandonment of the idealist position and the discovery of the power of the hysteric of narrating the experience of being. (shrink)

O autor realça a dicotomia entre asidéias de Homem e de Deus, igualmente enfocadaem J. P. Sartre e em Nietzsche. O conteúdo axiológicoem Deus contém a afirmação absoluta doHomem, logo, não são idéias contrárias, uma vezque o homem tende para Deus. As metas humanasestão contidas na idéias de Deus, portanto,não nos é lícito proclamar "a morte de Deus" antesque o homem se transforme em Deus...

Resenha : Engenharia Genética: busca da mercadoria perfeita? - SANDEL, Michael J. Contra a Perfeição: ética na era da engenharia genética. 1ª.ed. Tradução por Ana Carolina Mesquita. Rio de janeiro: Civilização Brasileira, 2013. 160p.

Rsenha da obra: GUTTMANN, Julius. 4 Filosofia do Judaismo — A História da Filosofia Judaica desde os Tempos Bíblicos até Franz Rosenzweig, São Paulo: Perspectiva, 2003, 480 p., Trad. de J. Guinsburg, Apresentação do Tradutor e Prefácio à edição Brasileira de Roberto Romano, Posfácio de Fritz Bamberger, ISBN 852730530-5.

D’Souza claims that near-death experiences (NDE) suggest that consciousness can outlive the breakdown of the body and cannot be explained as the product of dying brains. These experiences can be found in situations where a subject is not near death and have all the characteristics of hallucinations caused by oxygen deprivation. Despite thousands of cases, no one has every come back from an NDE with information that could not have been in their heads originally.

Bio-heteronormative conceptions of the family have long reinforced a nuclear ideal of the family as a heterosexual marriage, with children who are the genetic progeny of that union. This ideal, however, has also long been resisted in light of recent social developments, exhibited through the increased incidence and acceptance of step-families, donor-conceived families, and so forth. Although to this end some might claim that the bio-heteronormative ideal is not necessary for a social unit to count as a family, a more (...) systematic conceptualization of the family—the kind of family that matters morally—is relatively underexplored in the philosophical literature. This paper makes a start at developing and defending an account of the family that is normatively attractive and in line with the growing prevalence of non-conventional families and methods of family-formation. Our account, which we call a constitutive-affirmative model of the family, takes the family to be constituted by an ongoing process of relevant affective and affirmative relations between the putative family members. (shrink)

Austin takes on the problem of other minds, of how to respond to the question ‘how do you know?’, if this question is raised with regard to the thoughts, feelings, sensations, minds of other creatures. This problem has traditionally been understood as the problem of justifying our belief in the existence of other minds. Austin argues that believing in other persons, in authority and testimony, is an essential part of the act of communicating, and as such is an irreducible part (...) of our experience. While we can state certain advantages of communicative performances, there is no justification for our doing them as such. (shrink)