With In Search of Mechanisms, Carl F. Craver and Lindley Darden offer both a descriptive and an instructional account of how biologists discover mechanisms. Drawing on examples from across the life sciences and through the centuries, Craver and Darden compile an impressive toolbox of strategies that biologists have used and will use again to reveal the mechanisms that produce, underlie, or maintain the phenomena characteristic of living things. They discuss the questions that figure in the search for mechanisms, characterizing (...) the experimental, observational, and conceptual considerations used to answer them, all the while providing examples from the history of biology to highlight the kinds of evidence and reasoning strategies employed to assess mechanisms. At a deeper level, Craver and Darden pose a systematic view of what biology is, of how biology makes progress, of how biological discoveries are and might be made, and of why knowledge of biological mechanisms is important for the future of the human species. (shrink)

What does it mean to think about technology philosophically? Why try? These are the issues that Carl Mitcham addresses in this work, a comprehensive, critical introduction to the philosophy of technology and a discussion of its sources and uses. Tracing the changing meaning of "technology" from ancient times to our own, Mitcham identifies the most important traditions of critical analysis of technology: the engineering approach, which assumes the centrality of technology in human life and the humanities approach, which is (...) concerned with its moral and cultural boundaries. Mitcham bridges these two traditions through an analysis of discussions of engineering design, of the distinction between tools and machines, and of engineering science itself. He looks at technology as it is experienced in everyday life--as material objects (from kitchenware to computers), as knowledge ( including recipes, rules, theories, and intuitive "know-how"), as activity (design, construction, and use), and as volition (knowing how to use technology and understanding its consequences). By elucidating these multiple aspects, Mitcham establishes criteria for a more comprehensive analysis of ethical issues in applications of science and technology. This book will guide anyone wanting to reflect on technology and its moral implications. (shrink)

Alle Ideologie beruht auf Verdrängung der Gewalt; noch dort, wo sie Gewalt fetischisiert, bildet der blinde Fleck des Souveräns den Ursprung. Denn ausgeblendet wird ja nicht Gewalt als solche, sondern dass durch sie die Einheit der Gesellschaft erst Bestand hat. An diesem blinden Fleck tritt im Politischen selbst zutage, wie Aufklärung sich weigert, ihre eigenen Bedingungen zu begreifen – darin ist sie zunächst nichts anderes als die frühe Gestalt des Engagements. In dieser ›Dialektik des Leviathan‹, wie sie der erste Teil (...) des Buchs im Anschluss an die Dialektik der Aufklärung zu umreißen versucht, erhält die Gegenüberstellung von Hobbes und Spinoza eine Schlüsselrolle. Die These lautet, dass ein kritischer Begriff des Staats ohne die Kritik der spinozistischen Auffassung von Substanz nicht zu haben sei, deren problematische Aspekte nicht zufällig in der französischen (und italienischen) Linken (Althusser, Deleuze, Negri…) wiederkehrten. Umgekehrt war es gerade die Problematik dieses Substanzbegriffs, die es Marx erst ermöglichte – zusammen mit der Hegelschen Dialektik und zugleich gegen sie gerichtet – die Kritik der politischen Ökonomie zu entfalten. Wenn die neueste Ideologie der Linken wie der Rechten, in Frankreich wie in Deutschland, vielfach das Heideggersche »Sein« und den Carl Schmitt’schen »Begriff des Politischen« an die Stelle von Substanz und Souveränität setzt (Agamben, Badiou, Mouffe…), ist es mit jener ›Dialektik des Politischen‹ auf dem Boden der klassischen Metaphysik und Aufklärung nicht mehr getan. Dem heutigen Triumph Heideggers und Schmitts zu widersprechen, geht es im zweiten Teil des Buchs: Jean-Paul Sartres »Engagement gegen den Tod« und Jean Amérys Appell, den Leib zu »substantiieren« (wie das Manfred Dahlmann jüngst ausgedrückt hat), bedeuten einerseits Annäherung an die entscheidenden Fragen einer Philosophie nach Auschwitz – gerade auch, was die Frage des Souveräns betrifft. Andererseits verkehrte sich bei beiden regelmäßig die kritische Intention, sobald man den Gegenstand des Engagements mit der politischen Linken teilen und also Politik machen wollte. Dass sie vielmehr zu sabotieren sei, hat allerdings Améry – ohne sich dessen unbedingt bewusst zu sein – in seiner Parteinahme für Israel vorgeführt wie kaum ein anderer. Der von Adorno formulierte kategorische Imperativ, der zugleich das Politische als »Stand der Unfreiheit« begreift, erweist sich als die einzige Möglichkeit, dieser Sabotage auf den Grund zu gehen. Hier spannt sich aber auch der Bogen zum ersten Teil des Buchs zurück: Aus der Kritik an Spinozas Substanzbegriff lässt sich keine Kritik an Heideggers Sein zum Tode entwickeln, so wie auch der Gegensatz zwischen der Vernunft als Selbsterhaltung, die in der Dialektik der Aufklärung kritisiert wird, und der Vernichtung um der Vernichtung willen, die das Selbstopfer einschließt, dialektischer Vermittlung nicht mehr zugänglich ist, sondern zur Intervention nötigt. Davon legt jener Imperativ Zeugnis ab. Nur wer sich dabei jedoch die eigene Ohnmacht immer wieder eingesteht, die im notwendigen Engagement gegen den Antisemitismus so fatal wie nirgendwo hervortritt – spätestens dann, wenn der eben erst bezwungene Antisemit in neuer Gestalt wiederaufersteht –, wird auch die antisemitische bzw. antizionistische Gewalt nicht unterschätzen. (Diese Unterschätzung ist das Merkmal aller liberalen Anstrengungen, die Antisemiten zurückzudrängen.) Der dritte Teil schließlich versammelt – in Anlehnung an Adornos Engagement-Essay – Einzelstudien zur Kritik des politischen Engagements, wie sie sich an und in den Werken von Literatur und Essay, Musik und Film erschließt (Thomas Bernhard, Berthold Brecht, Hanns Eisler, Jean-Luc Godard, Elfriede Jelinek, Imre Kertész, Claude Lanzmann, Georg Lukács…). (shrink)

This book explores the phenomenon of the Third Reich from a philosophical perspective. It concentrates on the ways in which the subjects and experiences of Nazi Germany, the Holocaust and Anti-Semitism are conceived by eight German thinkers from the Continental tradition. These eight intellectuals include Martin Heidegger, Hannah Arendt, Karl Löwith, Carl Schmitt, Ernst Jünger, Jean Améry, Hans-Georg Gadamer, and Jan Assmann. Based on careful philosophical examinations of both known and unknown texts of these eight thinkers (including an English (...) translation of two forgotten texts by Schmitt and Jünger), this study exposes and then explores the tension between ideology and philosophy, between submission to authority and genuine critical thinking, all of which constitute the essence of the Continental philosophical tradition. This title was made Open Access by libraries from around the world through Knowledge Unlatched.--Provided by publisher. (shrink)

Luck egalitarianism is a family of egalitarian theories of distributive justice that aim to counteract the distributive effects of luck. This article explains luck egalitarianism's main ideas, and the debates that have accompanied its rise to prominence. There are two main parts to the discussion. The first part sets out three key moves in the influential early statements of Dworkin, Arneson, and Cohen: the brute luck/option luck distinction, the specification of brute luck in everyday or theoretical terms and the specification (...) of advantage as resources, welfare, or some combination of these. The second part covers three later developments: the democratic egalitarian critique of luck egalitarianism, the luck egalitarian acceptance of pluralism, and luck egalitarian doubts about the significance of the brute luck/option luck distinction. (shrink)

Mr. Wellman’s highly original contribution to the relatively new field of justification in ethics consists of characterizing the different ways in which ethical statements can be challenged and showing how each sort of challenge can be met by an appropriate response, enabling reasonable men to appropriately discuss or reflect on ethical issues. In developing his unique, systematic, methodology of ethics, Mr. Wellman has, first, rigorously reviewed and refuted the main arguments for the view of the nature of all reasoning as (...) deductive and, second, convincingly presented arguments for the existence of nondeductive evidences in ethics. Mr. Wellman’s broad definition of reasoning and his rejection of the identification of justification with reasoning reveals new dimensions of justification which will have wide implications in other areas of human speculation. (shrink)

Biologists rely heavily on the language of information, coding, and transmission that is commonplace in the field of information theory developed by Claude Shannon, but there is open debate about whether such language is anything more than facile metaphor. Philosophers of biology have argued that when biologists talk about information in genes and in evolution, they are not talking about the sort of information that Shannon’s theory addresses. First, philosophers have suggested that Shannon’s theory is only useful for developing a (...) shallow notion of correlation, the so-called causal sense of information. Second, they typically argue that in genetics and evolutionary biology, information language is used in a semantic sense, whereas semantics are deliberately omitted from Shannon’s theory. Neither critique is well-founded. Here we propose an alternative to the causal and semantic senses of information: a transmission sense of information, in which an object X conveys information if the function of X is to reduce, by virtue of its sequence properties, uncertainty on the part of an agent who observes X. The transmission sense not only captures much of what biologists intend when they talk about information in genes, but also brings Shannon’s theory back to the fore. By taking the viewpoint of a communications engineer and focusing on the decision problem of how information is to be packaged for transport, this approach resolves several problems that have plagued the information concept in biology, and highlights a number of important features of the way that information is encoded, stored, and transmitted as genetic sequence. (shrink)

Here, for the first time, the world's two leading authorities—Tom Regan, who argues for animal rights, and Carl Cohen, who argues against them—make their respective case before the public at large. The very terms of the debate will never be the same. This seminal moment in the history of the controversy over animal rights will influence the direction of this debate throughout the rest of the century.

Many political philosophers maintain that beneficiaries of injustice are under special obligations to assist victims of injustice. However, the examples favoured by those who endorse this view equally support an alternative luck egalitarian view, which holds that special obligations should be assigned to those with good brute luck. From this perspective the distinguishing features of the benefiting view are (1) its silence on the question of whether to allocate special obligations to assist the brute luck worse off to those who (...) are well off as a matter of brute luck but not as a result of injustice, and (2) its silence on the question of whether to allocate assistance to those who are badly off as a matter of brute luck but not as a result of injustice. In this new light, the benefiting view is harder to justify. (shrink)

Hodgkin and Huxley’s model of the action potential is an apparent dream case of covering‐law explanation in biology. The model includes laws of physics and chemistry that, coupled with details about antecedent and background conditions, can be used to derive features of the action potential. Hodgkin and Huxley insist that their model is not an explanation. This suggests either that subsuming a phenomenon under physical laws is insufficient to explain it or that Hodgkin and Huxley were wrong. I defend Hodgkin (...) and Huxley against Weber’s heteronomy thesis and argue that explanations are descriptions of mechanisms. †To contact the author, please write to: Department of Philosophy, Philosophy‐Neuroscience‐Psychology Program, Washington University in St. Louis, One Brookings Drive, Wilson Hall, St. Louis, MO 63130; e‐mail: [email protected]. (shrink)

_Not exercising as much as you should? Counting your calories in your sleep? Feeling ashamed for not being happier? You may be a victim of the wellness syndrome._ In this ground-breaking new book, Carl Cederström and André Spicer argue that the ever-present pressure to maximize our wellness has started to work against us, making us feel worse and provoking us to withdraw into ourselves. The Wellness Syndrome follows health freaks who go to extremes to find the perfect diet, corporate (...) athletes who start the day with a dance party, and the self-trackers who monitor everything, including their own toilet habits. This is a world where feeling good has become indistinguishable from being good. Visions of social change have been reduced to dreams of individual transformation, political debate has been replaced by insipid moralising, and scientific evidence has been traded for new-age delusions. A lively and humorous diagnosis of the cult of wellness, this book is an indispensable guide for everyone suspicious of our relentless quest to be happier and healthier. (shrink)

Understanding the 'making-up' relations, to put things neutrally, posited in mechanistic explanations the sciences is finally an explicit topic of debate amongst philosophers of science. In particular, there is now lively debate over the nature of the so-called 'realization' relations between properties posited in such explanations. Despite criticism (Gillett, Analysis 62: 316-323, 2002a), the most common approach continues to be that of applying machinery developed in the philosophy of mind to scientific concepts in what is known as the 'Flat' or (...) 'Subset' model of 'realization' (Kim, Mind in a physical world, 1998; Shapiro, J Philos XCVII: 635-654, 2000; Clapp, J Philos XCVIII: 111-136,2001 ; Wilson, Philos Stud 145: 149-169,2009). My primary goal in this paper is to show in still more detail that the Subset model of realization is inadequate for the descriptive task of describing the 'making-up' relations posited between properties or their instances in mechanistic explanations in the higher sciences. And my secondary goal is to highlight why this critique of the Subset view as a first-order descriptive account also shows there are deep difficulties in using the Subset account to address second-order issues in the philosophy of science as well. (shrink)

Based on author's dissertation--Yale University.

This chapter contains sections titled: Introduction The Once Received View (ORV) Criticisms of the ORV The “Model Model” of Scientific Theories Mechanisms: Investigating Nonformal Patterns in Scientific Theories Conclusion.

Bioethics is now taken seriously. Is there a danger of its being taken in or taken over? Might it be influenced in other ways, less visible and less easily avoided? As private corporations and bioethicists build relationships with each other, bioethicists must ask themselves about the opportunities, the constraints, and the subtle shifts in attitude and focus that such ties might create.

I have experienced the tribulations of fate.Victories and defeats, revolutions and restorations.Inflations and deflations, bombings,Defamations, broken regimes and broken pipes,Hunger and cold, internment and solitary confinement.Through it all I have passed,And through me it all has passed.I am acquainted with the abundant varieties of terror,The terror from above and the terror from below,Terror on the land and terror from the air,Terror legal and extra-legal,Brown, red and checkered terror,And worst of all, the terror none dares to name.I am acquainted with them (...) all and know their grip. (shrink)

Name der Zeitschrift: Deutsche Zeitschrift für Philosophie Jahrgang: 64 Heft: 6 Seiten: 894-924.

Rorty regards himself as furthering the project of the Enlightenment by separating Enlightenment liberalism from Enlightenment rationalism. To do so, he rejects the very need for explicit metaphysical theorizing. Yet his commitments to naturalism, nominalism, and the irreducibility of the normative come from the metaphysics of Wilfrid Sellars. Rorty's debt to Sellars is concealed by his use of Davidsonian arguments against the scheme/content distinction and the nonsemantic concept of truth. The Davidsonian arguments are used for Deweyan ends: to advance secularization (...) and anti-authoritarianism. However, Rorty's conflation of theology and metaphysics conceals the possibility of post-theological metaphysics. The key distinction lies between “metaphysics” and “Metaphysics.” The former provisionally models the relations between different vocabularies; the latter continues theology by other means. Sellars shows how to do metaphysics without Metaphysics. This approach complements Rorty's prioritization of cultural politics over ontology and his vision of Enlightenment liberalism without Enlightenment rationalism. (shrink)

Zhuangzi and Henry David Thoreau share a critical interest in the relations between wandering, nature, and experience. Their attitudes toward nature provide a basis for their views of human well-being, which in turn inform their attitudes toward language, society, and politics. Both celebrate nature as a source of constant novelty, change, and nourishing life. These values clash against social conformity and political homogeneity. For both Zhuangzi and Thoreau, how we experience life is already constitutive of human well-being. Wandering thus provides (...) a unique vision of freedom, one that binds experience, nature, and social-political criticism. (shrink)

Morphogen gradient theories have enjoyed considerable popularity since the beginning of this century, but conclusive evidence for a role of morphogens in controlling multicellular development has been elusive. Recently, work on three secreted signalling proteins, Activin in Xenopus, and Wingless and Dpp in Drosophila, has stongly suggested that these proteins function as morphogens. In order to define a factor as a morphogen, it is necessary to show firstly, that it has a direct effect on target cells and secondly, that it (...) affects the development of target cells in a concentration‐dependent manner. With these criteria in mind, the evidence available for a variety of proposed morphogens is discussed. While the evidence is not conclusive in most of the cases considered, there is a strong case in favour of the three proteins mentioned above, which suggests that morphogens are potentially of general importance in controlling the development of multicellular organisms. (shrink)

Several authors have made the argument that because blind evolutionary processes produced human intelligence on Earth, it should be feasible for clever human engineers to create human-level artificial intelligence in the not-too-distant future. This evolutionary argument, however, has ignored the observation selection effect that guarantees that observers will see intelligent life having arisen on their planet no matter how hard it is for intelligent life to evolve on any given Earth-like planet. We explore how the evolutionary argument might be salvaged (...) from this objection, using a variety of considerations from observation selection theory and analysis of specific timing features and instances of convergent evolution in the terrestrial evolutionary record. We find that, depending on the resolution of disputed questions in observation selection theory, the objection can either be wholly or moderately defused, although other challenges for the evolutionary argument remain. (shrink)

This remarkable book presents a rich and up-to-date view of evolution that explores the far-reaching implications of Darwin's theory and emphasizes the power, significance, and relevance of evolution to our lives today. After all, we ourselves are the product of evolution, and we can tackle many of our gravest challenges -- from lethal resurgence of antiobiotic-resistant diseases to the wave of extinctions that looms before us -- with a sound understanding of the science.

How should we understand the familiar demand that journalists ‘be objective’? One possibility is that journalists are under an obligation to report only the facts of the matter. However, facts need to be interpreted, selected, and communicated. How can this be done objectively? This paper aims to explain the concept of journalistic objectivity in methodological terms. Specifically, I will argue that the ideal of journalistic objectivity should be recast as a commitment to John Rawls’s conception of public reason. Journalism plays (...) a vital role in the operation of all modern liberal democracies, functioning as the public watchdog, the fourth estate, or the conduit through which vital information flows to the citizenry. Journalism is, therefore, an institution that is best understood as part of the basic structure of society. In Political Liberalism, Rawls explicitly excludes media of any kind from the demands of public reason because he doesn’t think that they play a political role that is important enough to bring them under the official auspices of public reason. I will argue that overlooking the political significance of journalism is a mistake, but one that can be corrected while keeping within the spirit and most important elements of his theory. This revision will widen the scope for what counts as journalism beyond traditional outlets and forms of media but will impose the demands of public reason on anyone who intends to participate in the institution. (shrink)

In his follow-up to Tavern League: Portraits of Wisconsin Bars, Carl Corey turns his camera on Wisconsin family-owned businesses in existence fifty years or longer. The businesses portrayed here—bakeries and barbecue joints, funeral homes and furniture builders, cheesemakers, fishermen, ferry boat drivers—have survived against all the odds, weathering tough economic times and big-business competition. The owners are loyal to their employees, their families, and themselves. And they are integral to their local economies and social fabric. The services and goods (...) they provide are usually for neighbors and friends. Generations serve generations, creating lasting relationships and strong, vibrant neighborhoods and rural communities. In For Love and Money, Carl Corey provides indelible glimpses of an increasingly endangered way of life. The Museum of Wisconsin Art’s Graham Reid has said, “As current and future generations come and go, these pictures will survive in the hands of the subjects, collectors, museums, and galleries. Will the businesses featured enjoy a similar longevity? Only time will tell, and we can only watch and hope, but Carl Corey has ensured that they will not be forgotten.”. (shrink)

Racial preferences are among the most contentious issues in our society, touching on fundamental questions of fairness and the proper role of racial categories in government action. Now two contemporary philosophers, in a lively debate, lay out the arguments on each side. Carl Cohen, a key figure in the University of Michigan Supreme Court cases, argues that racial preferences are morally wrong--forbidden by the 14th Amendment to the Constitution, and explicitly banned by the Civil Rights Act of 1964. He (...) also contends that such preferences harm society in general, damage the universities that use them, and undermine the minorities they were intended to serve. James P. Sterba counters that, far from being banned by the Constitution and the civil rights acts, affirmative action is actually mandated by law in the pursuit of a society that is racially and sexually just. The same Congress that adopted the 14th Amendment, he notes, passed race-specific laws that extended aid to blacks. Indeed, there are various kinds of affirmative action--compensation for past discrimination, remedial measures aimed at current discrimination, the guarantee of diversity--and Sterba reviews the Supreme Court cases that build a constitutional foundation for each. Affirmative action, he argues, favors qualified minority candidates, not unqualified ones. Both authors offer concluding comment on the University of Michigan cases decided in 2003. Half a century after Brown v. Board of Education, issues pertaining to racial discrimination continue to grip American society. Ideal for courses in political, social, ethical, and legal philosophy, this penetrating debate explores the philosophical and legal arguments on all sides of affirmative action, but also reveals the passions that drive the issue to the forefront of public life. (shrink)

Recent ethical misconduct in American business has resulted in volumes of written commentary, various legislative responses, as well as litigation by those identified as victims. While legislators, judges, juries, and the Securities and Exchange Commission (SEC) pursue an increasing number of cases, there is little attention devoted to understanding what drives executives and other leaders to behave in ways that violate the ethical and legal standards of business in the United States. This understanding is a prerequisite to selecting leaders and (...) designing interventions that prevent future misconduct. Understanding leadership’s nature and functioning is one key to understanding the ethical behavior of an organization as a system and of the people who lead the organization. Two models or frameworks provide the foundation for this paper. The first is a model of leadership competencies. This model identifies five key areas of competence related to overall, long-term leadership success. The second model targets leadership effectiveness. This model has three components – motivational patterns, decision criteria, and competencies. Using the Leadership Effectiveness Model to frame the discussion, the authors describe the nature and importance of the models, with particular focus on motivational patterns. Research suggests these patterns often account for 40–60% of overall leadership effectiveness. This article defines motivational patterns and describes key patterns that may impact ethical behavior of leaders. The article concludes with a discussion of how to use data on motivational patterns in leadership selection, development, and evaluation processes. (shrink)

The question “What makes a group of simultaneous experiences the experiences of a single person?” has been nearly ignored in the philosophical literature for the past few decades. The most common answer to this much neglected question is “Two simultaneous experiences belong to a single person if there is a common consciousness or awareness of them.” However, consciousness and awareness are difficult concepts to analyze, so that little of substance has been said of the answer. Recently, Oaklander has argued that (...) the awareness answer is deficient for a different reason, claiming that it fails because “it ultimately rests on an analysis of the unity of consciousness that is itself circular or otherwise inadequate” Oaklander 1987, p. 525). Oaklander's criticism is especially interesting because, according to it, the awareness account of synchronic personal identity falls prey to the main problem facing the memory account of diachronic identity, namely the problem of branching. In this paper, I shall argue that there is no important symmetry. Whatever its other flaws may be, the awareness account is immune to the branching problem; its immunity is due to formal differences between synchronic and diachronic identity. (shrink)

The main claim of this work is that scientific realism is of no great use in the philosophy of science. I define scientific realism as the claim that truth is neither to be regarded as an epistemological concept nor to be relativized to conceptual scheme. After clarifying my definition and showing how it relates to other characterizations of realism, I turn to the possible uses of scientific realism in the philosophy of science. Proponents of scientific realism claim that only their (...) position can ensure the possibility of communication between adherents of different scientific theories and that their position provides the best or only explanation for scientific progress. Scientific realists tend to regard these two areas as their position's areas of strength. I show that the scientific realist can solve these problems no better than his opponent. I conclude that if scientific realism is to be embraced as the only acceptable position in the philosophy of science, it will be because anti-realism is incoherent rather than pragmatically inferior. (shrink)

Among the many explanations for antibiotic overprescription, some doctors cite the risk of malpractice liability if they deny a patient's request for an antibiotic and the patient's condition worsens. In this paper, I examine the merits of this concern—i.e., whether physicians could, in fact, face malpractice liability for refusing to prescribe an antibiotic when, from a public health perspective, the use of the antibiotic would be considered inappropriate. I conclude that the potential for liability cannot be dismissed entirely, but the (...) risk is remote—even in cases where there is a chance that the antibiotic might have benefited the patient. (shrink)