Many historical studies have been devoted to the French school of molecular biology, in particular to the work of Jacques Monod on adaptive enzymes. By focusing on Francois Jacob's studies on lysogeny between 1950 and 1960, we intend to redress the imbalance of historiography, as well as proposing a more fruitful point of view for understanding the relative importance of international contacts and local traditions in the genesis of the operon model.Elie Wollman and Jacob's work on temperate bacteriophages rendered respectable (...) a system that had been considered an artefact for more than two decades. They did this firstly by modelling their studies on those of the US phage group and secondly by basing these studies on a complex vision of the relations between bacteria and bacteriophages. The interaction between bacteria and temperate bacteriophages was considered ab initio as a biochemical process, the mechanisms of which would eventually be characterized. It was also considered as a ''normal'' phenomenon that could be used as a model to understand the process of differentiation, as well as the role of viruses in diseases and cancer. The temperate bacteriophage was a model system that was far more epistemologically open and, for this reason, in a sense more productive than the virulent phage studied by the US phage group. (shrink)

The notion of computation has changed the world more than any previous expressions of knowledge. However, as know-how in its particular algorithmic embodiment, computation is closed to meaning. Therefore, computer-based data processing can only mimic life’s creative aspects, without being creative itself. AI’s current record of accomplishments shows that it automates tasks associated with intelligence, without being intelligent itself. Mistaking the abstract for the concrete has led to the religion of “everything is an output of computation”—even the humankind that conceived (...) the computer. The hypostatized role of computers explains the increased dependence on them. The convergence machine called deep learning is only the most recent form through which the deterministic theology of the machine claims more than what it actually is: extremely effective data processing. A proper understanding of complexity, as well as the need to distinguish between the reactive nature of the artificial and the anticipatory nature of the living are suggested as practical responses to the challenges posed by machine theology. (shrink)

Background The worldwide increase in older persons demands technological solutions to combat the shortage of caregiving and to enable aging in place. Smart home health technologies (SHHTs) are promoted and implemented as a possible solution from an economic and practical perspective. However, ethical considerations are equally important and need to be investigated. Methods We conducted a systematic review according to the PRISMA guidelines to investigate if and how ethical questions are discussed in the field of SHHTs in caregiving for older (...) persons. Results 156 peer-reviewed articles published in English, German and French were retrieved and analyzed across 10 electronic databases. Using narrative analysis, 7 ethical categories were mapped: privacy, autonomy, responsibility, human vs. artificial interactions, trust, ageism and stigma, and other concerns. Conclusion The findings of our systematic review show the (lack of) ethical consideration when it comes to the development and implementation of SHHTs for older persons. Our analysis is useful to promote careful ethical consideration when carrying out technology development, research and deployment to care for older persons. Registration We registered our systematic review in the PROSPERO network under CRD42021248543. (shrink)

Cécile Wick's work, oscillating among photography, painting, and drawing, is one of the most important oeuvres in contemporary Swiss art. Solo exhibitions in various galleries and a large retrospective at the Museum of Fine Art in Berne have recently showcased her prints and etchings to great acclaim. Cécile Wick. Colored Waters offers readers the first glimpse of the artist's more recent photographs and, in particular, drawings. Watercolors, ink drawings, inkjet prints and photographs are presented in series, putting media and motifs (...) in a dialogue and revealing new aspects of Wick's work. Around 160 color reproductions of artworks are complemented with essays by Martin Jaeggi and Nadine Olonetzky on subjects such as light, traces, signs, buildings, nature, and rhythm in Wick's oeuvre. (shrink)

The artistic work of photographer Gudio Baselgia focuses on landscapes formed by nature s forces and, more recently, on the sky with the stellar and solar movements and phenomena as we see them from earth. Celestial mechanics have fascinated mankind in all known cultures, the Babylonians and ancient Egyptians as well as the Greek and Celts, the Maya, or the ancient Indians and Chinese. Until the present day we look at the sky and keep being amazed, and try to read (...) what it tells us. Many artists throughout history have been captivated by the spectacle we observe above us day and night. The modern term astrodynamics describes all movements of celestial bodies, in particular the solar system including the moon and other satellites, asteroids and comets, but also movements of stars within a stellar system or galaxy, or of galaxies towards each other. They are well understood today and depicted in coordinate systems and elaborate visualizations. Guido Baselgia s artistic project on astrodynamics and celestial phenomena has no scientific or didactic ambition. His analogue camera is used as a recorder inscribing the movement of stars on the light-sensitive surface of photographic paper. Thus Baselgia s images make traceable the trajectory of celestial bodies invisible to the human eye and show us astounding occurrences of light and shadow. Baselgia has been captivated in particular also by the phenomenon of the umbra, planet earth s shadow thrown into space. It becomes visible occasionally on a clear evening at sunset when a slight mist lies at the horizon: looking in opposite direction to the sun, a dark and sharply marked band of shadow can be seen rising while sun sets behind the observer. But also by recording sunrise and sunset at the polar circle or the tropic, Baselgia visualizes the geometry of celestial mechanics and the concurrence of forces, as well as the miracle of light as such that leaves us awestruck today as much as it did our ancestors. The new book "Guido Baselgia Light Fall" presents 80 outstanding black-and-white images from the artist s Light Fall project taken in Norway, the Tierra del Fuego archipelago in Argentina, in Ecuador, and the Swiss Alps. The brilliant tritone plates are complemented with essays by the German scholar Andrea Gnam and Swiss photography critic Nadine Olonetzky. ". (shrink)

For more than twenty years, Swiss photographer Tobias Madörin has been working on his photo series Topos. Creating staged tableaux in the manner of nineteenth-century painters, Madörin investigates the interaction between the inhabitants and their surrounding environments in countries as diverse as Spain, Uganda, Indonesia, and Japan. His large-scale images examine communal spaces, the outskirts of metropolises, waste disposals sites, and landscapes marked by agriculture and mining. Madörin's work reveals that these locations are the products of human visions and ideals, (...) yet they are also places of environmental exploitation. This tension, as well as Madörin's intelligent and empathetic approach to his subjects, makes his photographs evocative and complex. This book includes lavish, full-page photographs, many of which have never been published, and an introductory essay by Nadine Olonetzky that explains and contextualizes the photographer's oeuvre. (shrink)

According to how AI has defined itself from its beginning, thinking in non-living matter, i.e., without life, is possible. The premise of symbolic AI is that operating on representations of reality machines can understand it. When this assumption did not work as expected, the mathematical model of the neuron became the engine of artificial “brains.” Connectionism followed. Currently, in the context of Machine Learning success, attempts are made at integrating the symbolic and connectionist paths. There is hope that Artificial General (...) Intelligence (AGI) performance can be achieved. As encouraging as neuro-symbolic AI seems to be, it remains unclear whether AGI is actually a moving target as long as AI itself remains ambiguously defined. This paper makes the argument that the intelligence of machines, expressed in their performance, reflects how adequate the means used for achieving it are. Therefore, energy use and the amount of data necessary qualify as a good metric for comparing natural and artificial performance. (shrink)

Aus einer philosophisch-phanomenologischen und literaturwissenschaftlichen Perspektive heraus gewinnt Nadine Benz nahere Erkenntnisse uber das temporale Phanomen des Wartens. Zunachst wird die historische Entwicklung der Zeitvorstellung aus philosophisch-phanomenologischer Sicht thematisiert, spezifisch im Hinblick auf die Fragen nach Messbarkeit, Vermitteltheit und nach objektiven und subjektiven Komponenten von Zeiterfahrung in ihrer Aporetik. Im Anschluss wird vom Konzept der Lebenswelt zur Literatur ubergeleitet: Die vorliegende Studie bindet die Aporien der Zeit zunachst theoretisch in eine Narratologie von Zeiterfahrung ein, die vor allem den Faktor (...) des Fiktiven produktiv berucksichtigt. Schliesslich werden die gewonnenen Erkenntnisse und Instrumente fur eine Analyse von Erzahltexten des 20. und 21. Jahrhunderts fruchtbar gemacht. Hier erlangen die literarischen Konfigurationen von Wartezeit als Semantiken des Wartens fur die Subjekte der fiktiven Zeiterfahrung einen konstitutiven Status. (shrink)

Controversies in food and agriculture abound, with many portrayed as conflicts between polarized viewpoints. Framing such controversies as dichotomies, however, can at times obscure what might be a plurality of views and potential common ground on the subject. We used Q methodology to explore stakeholders’ views about pesticide safety, agricultural worker exposure, and human health concerns in the tree fruit industry of central Washington State. Using a purposive sample of English and Spanish-speaking agricultural workers, industry representatives, state agencies, educators, and (...) advocates, participants sorted 45 statements on pesticide use and perceived human safety risks in the tree fruit industry in 2011. We used PQMethod 2.33 statistical software program to identify viewpoints, based on differences between how participants sorted the statements. The results revealed three distinct viewpoints among 38 sorters that explained 52 percent of the variance. The viewpoints included the: skeptics who expressed concern over the environmental and human health impacts of pesticide use; acceptors who acknowledged inherent risks for using pesticides but saw the risks as known, small and manageable; and incrementalists who prioritized opportunities to introduce human capital and technological improvements to increase agricultural worker safety. We then brought representatives with these different viewpoints together to analyze the results of the Q study, and to brainstorm mutually acceptable improvements to health and safety in tree fruit orchards. In describing and analyzing this case study, we argue that Q methodology can serve as one potentially effective tool for collaborative work, in this case facilitating a process of orchard safety improvements despite perceived stakeholder polarization. (shrink)

La philosophie de Baudrillard est inédite puisqu'il possède une façon originale de voir le monde, ses yeux étant ceux d'un philosophe-critique, d'un sociologue, d'un journaliste et d'un pataphysicien. Ce faisant, il possède une manière fort intéressante de nommer les faits. D'où toute la série de termes qu'il revisite ou invente surtout ceux formés par le préfixe hyper comme hyperconsommation, hypermarché, hyperréel, hypercorps, hyperespace et bien d'autres. Malgré sa quête du sens et du réel, Baudrillard débouche sur le non-sens et proclame (...) moyennement l'absence du réel. C'est comme si tout l'objectif de sa quête était uniquement la description du réel disparu et non la recherche et l'instauration du réel voire d'un nouveau réel. La recherche conduite ici s'attaque à la pensée hyperréelle de Jean Baudrillard tout en présentant l'originalité de cette pensée singulière et controversée. (shrink)

Zusammenfassung Der Beitrag stellt eine differenzierungstheoretische Perspektive auf Sportbeteiligung und Sportinteresse der Erwachsenenbevölkerung vor. Zugrunde liegen empirische Daten aus einer eigenen repräsentativen Bevölkerungsumfrage in Deutschland vom Herbst 2003, in der die Inklusion der Erwachsenen in sämtliche gesellschaftlichen Teilsysteme ermittelt wurde. Die Inklusion in den Sport wird mit Bezug auf die sekundäre Leistungsrolle des Breitensportlers und die Publikumsrolle des Sportzuschauers betrachtet; sodann wird möglichen Zusammenhängen zwischen der Ausprägung der Inklusion in den Sport mit ungleichheitstheoretisch geläufigen Merkmalen sozialer Lage, darüber hinaus dann (...) auch mit der Ausprägung anderer Inklusionsverhältnisse nachgegangen. (shrink)

This article re-examines the profession of the late antique mechanikos, who is identified as a practising architect with a sound liberal arts education as well as practical training. Despite the practical orientation of his profession, the mechanikos was of high social standing. This was possible because the practical utility of a vocation was increasingly acknowledged favourably in late antiquity and is reflected in early Byzantine portrayals of patrons, who allegedly invested hard labour in prestigious building campaigns and posed as the (...) supreme architects. (shrink)

Warning research participants and patients about potential risks associated with participation/treatment is a fundamental part of consent. However, such risk warnings might cause negative expectations and subsequent nocebo effects (i.e., negative expectations cause negative outcomes) in participants. Because no existing review documents how past research has quantitatively examined nocebo effects – and negative expectations – arising from consent risk warnings, we conducted a pre-registered scoping review (N = 9). We identified several methodological issues across these studies, which in addition to (...) mixed findings, limit conclusions about whether risk warnings cause nocebo effects. (shrink)

With robots being introduced into caregiving, particularly for older persons, various ethical concerns are raised. Among them is the fear of replacing human caregiving. While ethical concepts like well-being, autonomy, and capabilities are often used to discuss these concerns, this paper brings forth the concept of social dignity to further develop guidelines concerning the use of robots in caregiving. By social dignity, we mean that a person’s perceived dignity changes in response to certain interactions and experiences with other persons. In (...) this paper, we will first present the concept of social dignity, and then identify a niche where robots can be used in caregiving in an ethical manner. Specifically, we will argue that, because some activities of daily living are performed in solitude to maintain dignity, a care recipient will usually prefer robotic assistance instead of human assistance for these activities. Secondly, we will describe how other philosophical concepts, which have been commonly used to judge robotic assistance in caregiving for the elderly so far, such as well-being, autonomy, and capabilities, are less useful in determining whether robotic assistance in caregiving is ethically problematic or not. To conclude, we will argue that social dignity offers an advantage to the other concepts, as it allows to ask the most pressing questions in caregiving. (shrink)

A partir de l’étude de corpus de textes, manuelle et informatique, nous présentons une réflexion sur l’analyse de texte ou de discours à travers l’exemple de l’exposition didactique. Celle-ci peut s’envisager à différents grains. Nous posons la question de la taille du texte, de son style collectif à travers sa disposition et ses marques. Nous interrogeons la pertinence du modèle choisi en relation avec la notion d’échelle. Enfin, nous posons la question de la résolution adéquate pour des logiciels d’analyse, à (...) l’aide d’une dizaine d’exemples. (shrink)

A partir de l’étude de corpus de textes, manuelle et informatique, nous présentons une réflexion sur l’analyse de texte ou de discours à travers l’exemple de l’exposition didactique. Celle-ci peut s’envisager à différents grains. Nous posons la question de la taille du texte, de son style collectif à travers sa disposition et ses marques. Nous interrogeons la pertinence du modèle choisi en relation avec la notion d’échelle. Enfin, nous posons la question de la résolution adéquate pour des logiciels d’analyse, à (...) l’aide d’une dizaine d’exemples. (shrink)

Pregnancy is thought to be a metabolically very expensive endeavor, yet investigations have produced inconsistent results concerning the responsiveness of human birth weight to maternal nutritional stress or nutritional intervention. These findings have led some researchers to conclude that fetal growth is strongly buffered against fluctuations in maternal energy balance, making the fetus in effect a “nearly perfect parasite.” This buffering would appear to be a reasonable adaptive response given the high risk of morbidity and mortality associated with low birth (...) weight. However, a life-history approach leads to the prediction that maternal investment strategies in pregnancy should be geared toward maximizing lifetime reproductive success rather than simply the success of the current pregnancy, and by extension that maternal investment strategies should vary with reproductive value. The physiology of human pregnancy in fact appears to include a number of mechanisms that protect maternal energy resources from diversion to the fetus and preserve them for future reproductive events. These mechanisms include adjustment of blood flow to the uterus and perhaps minor adjustments in gestation length, although evidence for the latter is scant. Suggestions are made for ways of investigating these maternal options. (shrink)

In his article “Issues of Pragmaticism” published in 1905, in The Monist, Charles S. Peirce complains that “Logicians have been at fault in giving Vagueness the go-by, so far as not even to analyze it.” That same year, occupying himself with the consequences of “Critical commonsensism,” he affirmed, “I have worked out the logic of vagueness with something like completeness,” a statement that causes the majority of the commentators on his work, including the editors of the Collected Papers to ask (...) where this logic is to be found. The fever for finding Peirce's manuscripts is fed by the hope of some researchers of discovering the logic of vagueness, a hope that has grown since Carolyn Eisele's publication of his mathematical works. Others - and I count myself among them - believe that in reality this is a matter of something already known. That is, they interpret the affirmation ending the paragraph of reproach addressed to logicians, “The present writer has done his best to work out the Stechiology, Critic, and Methodeutik of the subject,” as a tripartite semiotic of the vague, still limited, according to Peirce's older works, to symbols, that is, to the signs of natural language examined from the perspective of logic. (shrink)

Supervenient libertarianism maintains that indeterminism may exist at a supervening agency level, consistent with determinism at a subvening physical level. It seems as if this approach has the potential to break the longstanding deadlock in the free will debate, since it concedes to the traditional incompatibilist that agents can only do otherwise if they can do so in their actual circumstances, holding the past and the laws constant, while nonetheless arguing that this ability is compatible with physical determinism. However, we (...) argue that supervenient libertarianism faces some serious problems, and that it fails to break us free from this deadlock within the free will debate. (shrink)

The current assumptions of knowledge acquisition brought about the crisis in the reproducibility of experiments. A complementary perspective should account for the specific causality characteristic of life by integrating past, present, and future. A “second Cartesian revolution,” informed by and in awareness of anticipatory processes, should result in scientific methods that transcend the theology of determinism and reductionism. In our days, science, itself an expression of anticipatory activity, makes possible alternative understandings of reality and its dynamics. For this purpose, the (...) study advances G-complexity for defining and comparing decidable and undecidable knowledge. AI and related computational expressions of knowledge could benefit from the awareness of what distinguishes the dynamics of life from any other expressions of change. (shrink)

Fox and Spector use multiple instances of the exhaustivity operator EXH to derive the correct meaning of utterances that include pitch-focus marked disjunction in downward-entailing environments. They argue that the \ operator evaluates alternatives to be used by EXH. Though the method is sound and gets the right result, we argue that the way in which EXH would need to interact with other instances of EXH, as well as other focus-sensitive elements, is at odds with how EXH is used to (...) explain other phenomena. Specifically, the analysis in Fox and Spector predicts intervention effects for cases where EXH interacts with other focus-sensitive elements. This is problematic for many cases in which EXH is used to derive the desired inferences. We propose a different way of focus association for EXH that would work for the approach introduced in Fox and Spector as well as elsewhere. In addition, our account does not require a covert element to be focused. (shrink)

Trois lois ont, entre 1993 et 2002, codifié le dispositif français dit de « l’accouchement sous X », qui autorise une femme à accoucher gratuitement dans une maternité sans révéler son identité. La première a durci ce dispositif en l’insérant dans le code civil, la seconde a tenté de l’assouplir et la dernière a créé un organisme chargé de faciliter, pour les personnes nées « sous X », l’accès à la connaissance de leurs origines. Dans les débats parlementaires qui ont (...) précédé l’adoption de ces lois, l’histoire a largement été utilisée comme argument, mais on est passé de l’histoire nationale à l’histoire personnelle, et de la « tradition française » justifiant le maintien du secret de l’accouchement, au droit à la vérité de la biographie légitimant la possibilité de la réversibilité du secret. (shrink)

Cet important ouvrage de l’historienne Sasha Turner porte sur la période de 1780 à 1834 à la Jamaïque, période pendant laquelle la perspective de l’abolition de la traite (qui interviendra en 1807), puis de l’esclavage lui-même, conduisit, là comme ailleurs, les différents acteurs du système esclavagiste à réviser la politique jusqu’alors menée en matière de reproduction de la main d’œuvre et à adopter, bon gré mal gré, une politique nataliste. La connaissance des conditions de vie des femmes...

In her recently published monography Transformative Experience L.A. Paul has defended a concept of ‘lived experience’ that is meant to account for the transformative effects of major life decisions. According to Paul, “humans vary so much and so deeply, that even small differences (contextually speaking) in experiences between people can prevent us from knowing what it is like to be a different type of person” (Paul 2014, 7). In this article I will argue that Paul's account results from a problematic (...) conception of lived experience that cannot account for the intersubjective dimensions of personal experience, i.e. for the fact that our lived experience is intrinsically tied to our relationships with others. These, however, are of central import to our ethical practice, e. g. in raising awareness for the particular experiences and needs of others. After providing some introductory remarks concerning the concept of ‘lived experience’ in section I, the aim of section II is to critically investigate Paul's conception of ‘lived experience’ and to show that her approach not only rests on highly contestable assumptions but yields several unplausible consequences. Given these problems, I will suggest an alternative account of lived experience in section III. I will argue that mental phenomena like pain, sadness or desperation have characteristic manifestations in linguistic and non-linguistic behaviour which are part of the concept of a particular mental phenomenon. It is due to this that we possess intersubjective criteria that enable us to ascribe mental properties to ourselves as well as to others. The alternative account can thereby avoid the problems that are concomitant with Paul's approach. It can nevertheless take into account the distinct perspective of first person ‘lived experiences’. (shrink)

Values and virtues play an important role in military organizations. In particular, armies can be understood as institutions that are guided by values and virtues, endeavoring to promote them. A common understanding within the military organization relating the relevant values and virtues is therefore essential. In many armed forces, there are lists of relevant values and virtues that have mostly grown historically. In the context of this volume, special emphasis has been devoted to the value and virtue culture and its (...) importance within a military organization. Specifically, the dimensional structure of values and virtues was analyzed. Through a systematic survey of the military target groups and a factor analytical assessment within the Swiss Armed Forces, the core values and virtues were categorized and defined. These values and virtues describe the current culture of the Swiss Armed Forces and contribute to a more binding support of the objectives of military education. (shrink)

Susser and Cabrera (2024) assess the role of bespoke neuro-privacy regulations including the creation of a novel right to mental privacy. They argue that focusing on what distinguishes mental priva...