Diffusion theory explains in physical terms how materials move through a medium, e.g. water or a biological fluid. There are strong and widely acknowledged grounds for doubting the applicability of this theory in biology, although it continues to be accepted almost uncritically and taught as a basis of both biology and medicine. Our principal aim is to explore how this situation arose and has been allowed to continue seemingly unchallenged for more than 150 years. The main shortcomings of diffusion theory (...) will be briefly reviewed to show that the entrenchment of this theory in the corpus of biological knowledge needs to be explained, especially as there are equally valid historical grounds for presuming that bulk fluid movement powered by the energy of cell metabolism plays a prominent note in the transport of molecules in the living body. First, the theory's evolution, notably from its origins in connection with the mechanistic materialist philosophy of mid nineteenth century physiology, is discussed. Following this, the entrenchment of the theory in twentieth century biology is analyzed in relation to three situations: the mechanism of oxygen transport between air and mammalian tissues; the structure and function of cell membranes; and the nature of the intermediary metabolism, with its implicit presumptions about the intracellular organization and the movement of molecules within it. In our final section, we consider several historically based alternatives to diffusion theory, all of which have their precursors in nineteenth and twentieth century philosophy of science. (shrink)

This paper considers Margaret Cavendish's distinctive anti-mechanist materialism, focusing on her 1664 Philosophical Letters, in which she discusses the views of Hobbes, Descartes, and More, among others. The paper examines Cavendish's views about natural, material souls: the soul of nature, the souls of finite individuals, and the relation between them. After briefly digressing to look at Cavendish's views about divine, supernatural souls, the paper then turns to the reasons for Cavendish's disagreement with mechanist accounts. There are disagreements over the (...) explanation of particular phenomena, but also a broader disagreement over what to take as one's most basic causal model. (shrink)

Robert Schofield explores the rational elements of British experimental natural philosophy in the 18th century by tracing the influence of two opposing concepts of the nature of matter and its action—mechanism and materialism. Both concepts rested on the Newtonian interpretation of their proponents, although each developed more or less independently. By integrating the developments in all the areas of experimental natural philosophy, describing their connections and the influences of Continental science, natural theology, and to a lesser degree social and (...) institutional changes, the author demonstrates that mechanistic concepts dominated interpretations from about 1687 to 1740, when they were replaced by materialistic concepts. A revival of the mechanistic approach early in the next century made England a fertile field for ideas on the dynamic interaction of forces. Originally published in 1970. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These paperback editions preserve the original texts of these important books while presenting them in durable paperback editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905. (shrink)

ABSTRACTThe paper focuses on the gradual separation between materialism and mechanism in early modern German philosophy. In Germany the distinction between the two concepts, originally introduced by Leibniz, was definitively stated by Wolff who was the first to provide a definition of the new philosophical term Materialismus, and of the related philosophical sect. In the first part I describe the initial identification of mechanism and materialism in German philosophy between the last decades of the seventeenth century and 1720. (...) Mechanism is here mostly conceived within a monistic metaphysics of body, which refers mainly to Hobbes and to some interpretations of Spinoza’s pantheism. This tight connection between a mechanical explanation of nature and the Deus sive natura issue leads to a negative judgement on mechanism and its materialistic implications, both charged with a form of more or less explicit atheism. In the second part I describe the gradual emancipation in Germany of mechanism fro... (shrink)

ABSTRACT: Hobbes belonged to philosophical and scientific circles grappling with the big question at the dawn of modern physics: materialism and its consequences for morality. ‘Matter in motion’ may be a core principle of this materialism but it is certainly inadequate to capture the whole project. In wave after wave of this debate the Epicurean view of a fully determined universe governed by natural laws, that nevertheless allows to humans a sphere of libertas, but does not require a (...) creator god or teleology to explain it, comes up against monotheism and its insistence on the incoherence of an ordered world in the absence of a God and his purposes. The following questions were central to this debate: Can we understand the universe as law-governed in the absence of a god? If so, what room is there in a fully determined mechanical universe for human freedom? If humans do enjoy freedom, does the same hold for other animals? Is this freedom compatible with standard views of morality? (shrink)

Urban Gottfried Bucher is one of the most surprising authors in early German enlightenment and has been rightly celebrated as a materialist and therefore radical thinker. But he did not teach the same kind of materialism as his contemporary Andreas Rüdiger who leaned toward Locke’s empiricism. Bucher is much closer to Hobbes’ mechanical materialism, to Spinoza’s criticism of free will, and to Tschirnhaus’ extending of the mathematical method to natural science. His explanation of the working of the human (...) soul, while materialistic, is rationalistic and mechanical. The difference between the two kinds of materialism becomes crystal-clear in Bucher’s and Rüdiger’s approach to the Copernican system they both embrace. For Rüdiger, the Copernican hypothesis is seen as a probable truth we can hold on to as long as we don’t obtain competing empirical sensiones and ideas, even if our globe should not really move around the sun. For Bucher though, it is a demonstrated truth that gains additional support by a machin... (shrink)

The word 'materialism' is ambiguous: it designates a moral doc trine as well as a philosophy and, indeed, an entire world view. Moral materialism is identical with hedonism, or the doctrine that humans should pursue only their own pleasure. Philosophical ma terialismis the view that the real worId is composed exclusively of material things. The two doctrines are logically independent: hedonism is consistent with immaterialism, and materialism is compatible with high minded morals. We shall be concerned ex (...) c1usively with philosophical materialism. And we shall not confuse it with realism, or the epistemological doctrine that knowIedge, or at any rate scientific knowledge, attempts to represent reality. Philosophical materialism is not a recent fad and it is not a solid block: it is as old as philosophy and it has gone through six quite different stages. The first was ancient materialism, centered around Greek and Indian atomism. The second was the revival of the first during the 17th century. The third was 18th century ma terialism, partly derived from one side of Descartes' ambiguous legacy. The fourth was the mid-19th century "scientific" material ism, which flourished mainly in Germany and England, and was tied to the upsurge of chemistry and biology. The fifth was dialec tical and historical materialism, which accompanied the consolida tion of the socialist ideology. And the sixth or current stage, evolved mainly by Australian and American philosophers, is aca demic and nonpartisan but otherwise very heterogeneous. Ancient materialism was thoroughly mechanistic. (shrink)

From Hegel to Engels, Sartre and Ruyer (Ruyer, 1933), to name only a few, materialism is viewed as a necropolis, or the metaphysics befitting such an abode; many speak of matter’s crudeness, bruteness, coldness or stupidity. Science or scientism, on this view, reduces the living world to ‘dead matter’, ‘brutish’, ‘mechanical, lifeless matter’, thereby also stripping it of its freedom (Crocker, 1959). Materialism is often wrongly presented as ‘mechanistic materialism’ – with ‘Death of Nature’ echoes of (...) de-humanization and hostility to the Scientific Revolution (which knew nothing of materialism!), also a powerful Christian theme in Cudworth, Clarke and beyond (Overhoff, 2000). Here I challenge this view, building on some aspects of Israel’s Radical Enlightenment concept (Israel, 2001), which has been controversial but for my purposes is a useful claim about the dissemination of a home-grown Spinozism, sometimes reformulated as an ontology of the life sciences, an aspect Israel does not address (compare Secrétan et al., eds., 2007; Citton, 2006). First, I examine some ‘moments’ of radical Enlightenment materialism such as La Mettrie and Diderot (including his Encyclopédie entry “Spinosiste”), but also anonymous, clandestine texts such as L’Âme Matérielle, to emphasize their distinctive focus on the specific existence of organic beings. Second, I show how this ‘embodied’, non-mechanistic character of Enlightenment ‘vital materialism’ makes it different from other episodes, and perhaps more of an ethics than is usually thought (also via the figure of the materialist as ‘laughing philosopher’). Third, I reflect on what this implies for our image of the Enlightenment – no longer a Frankfurt School and/or Foucaldian vision of ‘discipline’, regimentation and order (as in Mayr, 1986) – but ‘vital’, without, conversely, being a kind of holist vitalism “at odds with the universalizing discourse of Encyclopedist materialism, with its insistence on the uniformity of nature and the universality of physical laws” (Williams, 2003): vital materialism is still materialism. Its ethics tends towards hedonism, but its most radical proponents (Diderot, La Mettrie and later Sade) disagree as to what this means. (shrink)

The report of B. M. Hessen at the I All-Union Congress of physicists. The Congress was held in Odessa from 19 to 24 August 1930. At the plenary meeting B. M. Hessen, made a report on methodological issues of quantum physics, the relationship of physics and philosophy. Mechanistic materialism in his time came to replace the scholastic physics. But he could not solve the problems of development and specificity of forms of movement. B. M. Hessen believed that the (...) development of the basic concepts of natural science (matter, space and time, motion, wave and particle, pattern and randomness) coincides with the approach of dialectical materialism. (shrink)

The materialist approach to the body is often, if not always understood in ‘mechanistic’ terms, as the view in which the properties unique to organic, living embodied agents are reduced to or described in terms of properties that characterize matter as a whole, which allow of mechanistic explanation. Indeed, from Hobbes and Descartes in the 17th century to the popularity of automata such as Vaucanson’s in the 18th century, this vision of things would seem to be correct. In (...) this paper I aim to correct this inaccurate vision of materialism. On the contrary, the materialist project on closer consideration reveals itself to be, significantly if not exclusively, (a) a body of theories specifically focused on the contribution that ‘biology’ or rather ‘natural history’ and physiology make to metaphysical debates, (b) much more intimately connected to what we now call ‘vitalism’ (a case in point is the presence of Théophile de Bordeu, a prominent Montpellier physician and theorist of vitalism, as a fictional character and spokesman of materialism, in Diderot’s novel D’Alembert’s Dream), and ultimately (c) an anti-mechanistic doctrine which focuses on the unique properties of organic beings. To establish this revised vision of materialism I examine philosophical texts such as La Mettrie’s Man a Machine and Diderot’s D’Alembert’s Dream; medical entries in the Encyclopédie by physicians such as Ménuret and Fouquet; and clandestine combinations of all such sources (Fontenelle, Gaultier and others). (shrink)

I present a condensed exposé of systemic materialism, a synthesis of materialism and systemism originally proposed by Mario Bunge. Matter is identified with mutability of propertied particulars, and a concrete or material system is defined as an object with composition, structure, mechanism, and environment. I review different aspects of this ontology, and discuss some of its implications for epistemology, ethics, and aesthetics. I also try to identify some problems of this view and offer some ways to overcome the (...) difficulties. I conclude that systemic materialism is a promising philosophical project still in the making. (shrink)

Early modern critics of materialism (and of associated doctrines like determinism and mechanism) sometimes employed a transcendental argument form. If materialism were true, then some valuable feature of reality could not exist; but that feature does exist; therefore materialism is false. Depending on current context and concerns, the valuable 'X' in question might be God, the soul, hell, objective morality, free will, conscience, truth, knowledge, social order, or justice and the law: all, in the critics' eyes, obvious (...) and unchallengeable realities which materialism would, impossibly, extinguish.1 As David Hawkes notes in his delightfully provocative essay, it is because Hell is so manifestly real, in both the play and its world, that Faustus manifestly refutes himself in telling Mephistopheles that it is a fable. The success of such transcendental arguments relies on the truth of both their premises: Hell really must exist, and Faustus's materialism must really be incompatible with its existence. Hawkes celebrates early modern moralists who focussed on the alleged worldly and carnal roots and consequences of 'philosophical materialism', who attacked its proponents as villainous, self-interested, and depraved. (shrink)

The causal efficacy of a material system is usually thought to be produced by the law-like actions and interactions of its constituents. Here, a specific system is constructed and explained that produces a cause that cannot be understood in this way, but instead has novel and autonomous efficacy. The construction establishes a proof-of-feasibility of strong emergence. The system works by utilizing randomness in a targeted and cyclical way, and by relying on sustained evolution by natural selection. It is not vulnerable (...) to standard arguments against strong emergence, in particular ones that assume that the physical realm is causally closed. Moreover, it does not suffer from epiphenomenalism or causal overdetermination. The system uses only standard material components and processes, and is fully consistent with naturalism. It is discussed whether the emergent cause can still be viewed as ‘material’ in the way that term is commonly understood. (shrink)

New materialism challenges conventional theories of understanding human being and subjectivity, which it regards as shaped by mechanistic models characteristic of early modern philosophy that regarded matter as largely passive. Instead it gives weight to topics often overlooked in such accounts: the body, the role of affect and the emotions, gender, temporality, agency and vitalism. This collection, which includes an international roster of contributors from philosophy, history, literature and science, is the first to ask what is 'new' about (...) the new materialism and place it in interdisciplinary perspective. Against current theories of new materialism it argues for a deeper engagement with materialism's history; questions whether matter can be 'lively'; and asks whether new materialism's wish to revitalize of politics and the political lives up to its promise. (shrink)

Originally published in 1929, McDougall examines the pertinent conflict between religion and science. His work exhibits the failure of scientists to explain human action mechanistically, establishes purposive action as a type of event radically different from all mechanistic events, and justifies the belief in teleological causation without which there can be neither religion nor morals. This title will be of interest to students of both the Humanities and Sciences, particularly those studying psychology and philosophy.

This article deals with the concept of “mechanism” from a historical point of view, focusing on its relationship with the evolution of hylomorphism in the 17th century. I try to address the following questions: is mechanism structurally bound to materialism or does it rather represent a form of complete determinism, reconcilable with an “updated” version of hylomorphism? In the first part of the essay, I make the point that the very notion of “mechanism” must be clarified by means of (...) a distinction between Boylean experimental mechanism and what Daniel Garber has called the “pre-history of the Mechanical Philosophy”. My aim is to highlight how the deterministic (and nominalistic) hylomorphism developed in the 17th Century came quite close to mechanism. In this framework, I present the ‘strange case’ of Marin Cureau de La Chambre (1594-1669), which represents a characteristic compromise – based on the possibility of a not bodily extension – between a deterministic mechanization of the lower functions of the vegetative and sensitive soul and Campanella’s panpsychism. (shrink)

New materialism challenges conventional theories of understanding human being and subjectivity, which it regards as shaped by mechanistic models characteristic of early modern philosophy that regarded matter as largely passive. Instead it gives weight to topics often overlooked in such accounts: the body, the role of affect and the emotions, gender, temporality, agency and vitalism. This collection, which includes an international roster of contributors from philosophy, history, literature and science, is the first to ask what is 'new' about (...) the new materialism and place it in interdisciplinary perspective. Against current theories of new materialism it argues for a deeper engagement with materialism's history; questions whether matter can be 'lively'; and asks whether new materialism's wish to revitalize of politics and the political lives up to its promise. (shrink)

ABSTRACTBecause of their reliance on mechanistic metaphors and analogies referring to machines, the eighteenth-century materialists La Mettrie and Diderot have sometimes been described as ‘mechanistic materialists’. However, if one pays close attention to the ways in which mechanical analogies and metaphors were used in eighteenth-century French materialism, one sees that the recourse to these metaphors and comparisons in no way implies mechanism in the sense of physicalist reductionism. Instead, early instances of these comparisons appear in arguments pointing (...) out that technological artefacts have functional properties which are not reducible to their physical properties. When La Mettrie compares man to a machine in his L'homme machine, he insists at the same time on the fact that, just like a machine, man is a cultural artefact. According to La Mettrie, man's very existence depends on language and culture, and it is precisely this dependence on culture which distinguishes him from other animals. However... (shrink)

Sun Yatsen , pioneer of modern China's great democratic revolution, was a materialist philosopher. Inheriting the tradition of simple materialism of ancient China and absorbing modern Western mechanistic materialist thought, he relied on a knowledge of the natural sciences to develop his own naturalistic view of mechanistic materialism. This was an important element in the structure of his world view.

There is an enduring story about empiricism, which runs as follows: from Locke onwards to Carnap, empiricism is the doctrine in which raw sense-data are received through the passive mechanism of perception; experience is the effect produced by external reality on the mind or ‘receptors’. Empiricism on this view is the ‘handmaiden’ of experimental natural science, seeking to redefine philosophy and its methods in conformity with the results of modern science. Secondly, there is a story about materialism, popularized initially (...) by Marx and Engels and later restated as standard, ‘textbook’ history of philosophy in the English-speaking world. It portrays materialism as explicitly mechanistic, seeking to reduce the world of qualities, sensations, and purposive behaviour to a quantitative, usually deterministic physical scheme. Building on some recent scholarship, I aim to articulate the contrarian view according to which neither of these stories is true. On the contrary, empiricism turns out to be less ‘science-friendly’ and more concerned with moral matters; materialism reveals itself to be, in at least a large number of cases, a ‘vital’, anti-mechanistic doctrine which focuses on the unique properties of organic beings. This revision of two key philosophical episodes should reveal that our history of early modern philosophy is dependent to a great extent on ‘special interests’, whether positivistic or Kantian, and by extension lead us to rethink the relation and distinction between ‘science’ and ‘philosophy’ in this period. (shrink)

Neuroconstructivism is a hybrid of two incompatible philosophical traditions: a radical idealism insisting upon the free activity of the Subject; and a radical materialistic anthropomorphism, which ascribes inherent properties of humans (e.g., the ability to construct) to nonhuman objects or body parts (e.g., the brain). The two traditions can be combined only by obscuring or confusing the basic notions.

Argues for an evolutionary mechanism to underpin the functional explanations at the center of Karl Marx's theory of history.

Glenn Pearce, labels the identification of the firing of one's pain centres in the brain with feeling pain ‘a naive view,’ the refutation of which cannot much threaten any serious version of materialism. But in fact at least a dozen proponents of contemporary materialism have already hypothesized the identification of feeling pain with activation of a specific neural mechanism, although they picked the wrong mechanism, namely C-fibres. Just to take a recent example, James Cornman and Keith Lehrer, trying (...) to get around the objection to the identity theory that the language of neural processes and the language of feeling pains belong to different linguistic categories, suggest that the materialist could devise a new term to refer to the same entity across categories: ‘fibain.’They write,He would then claim that there are fibains, that is, entities with those properties usually associated with pains, and also with the properties usually associated with firing C-fibers. He can, then, avoid category mistakes by saying that what are thought to be pains and what are thought to be firing C-fibers are really fibains. (shrink)

What is the relationship between pain and the body? I claim that pain is best explained as a type of personal experience and the bodily response during pain is best explained in terms of a type of mechanical neurophysiologic operation. I apply the radical philosophy of identity theory from philosophy of mind to the relationship between the personal experience of pain and specific neurophysiologic mechanism and argue that the relationship between them is best explained as one of type identity. Specifically, (...) pain is a specific type of personal experience identical to a specific type of allostatic stress response comprised of interdependent nervous, endocrine and immune mechanical operations. (shrink)

I shall be concerned in this paper with the consideration of panpsychism and of materialism in new forms as alternatives. Extended reference will be made to C. S. Peirce's view of perception as realistic in intention and yet not quite clear as to its mechanism and how it attains objective import. I shall say little about Whitehead as a representative of panpsychism as I have just finished a detailed criticism of his epistemological framework. I shall, however, make comments on (...) William James's radical empiricism as tied in with his view of perception as direct and immediate--roughly speaking, the alternative to Locke's representation of "unperceived things" --and bring in my own theory of sensations as guiding perceiving. Russell's neutral monism, connected historically with James's radical empiricism, will be touched on here in connection with his rejection of materialism. Phenomenalism and materialism exclude each other. Materialism, as an ontology, requires a realistic epistemology. I shall also make some comments on Dewey's biological experientialism. One can often best explain a perspective by means of contrasts. (shrink)

What is the use of trying to describe a philosophy as ‘materialistic’ or ‘idealistic’? Why multiply the species of each genus? We have ‘subjective’, ‘absolute’, and ‘objective’ idealism, ‘mechanistic’ and ‘dialectical’ materialism, to which we must now add ‘uncertain’ or ‘random’ materialism. Must we worry if a philosophy belongs to this or that ‘trend’, ‘current’, or ‘tradition’? We find ourselves asking all these types of questions when reading Louis Althusser’s later work, in which he appears to have (...) devoted some effort to developing the idea of an “underground” or “subterranean” trend in philosophy. After some hesitation, he termed this “materialism of the encounter” or “uncertain materialism,” which I will refer to hereafter in abbreviated form as UM. (shrink)

We are concerned with two modes of describing the dynamics of natural systems. Global descriptions require simultaneous global coordination of all dynamical operations. Global dynamics, including mechanics, remain invariant in the absence of external perturbation. But, failing impossible global coordination, dynamical operations could actually become coordinated only locally. In local records, as in global ones, the law of the excluded middle would be strictly observed, but without global coordination it could only be fullfilled sequentially by passing causative factors forward onto (...) subsequent contiguous operations.The local dynamics of sequential operations would be indefinite with regard to how commitments will be made which will avoid violating the law of the excluded middle, but any resulting record will be as definite as if there had been global coordination. While maintaining an agential capacity for making contingent choices internally, local dynamics could be cumulated into a global record of seemingly simultaneous operations. Natural selection within a framework of local dynamics would have a capacity for making opportunistic commitments, but its effects in a posterior record can be reduced to the mechanistic neodarwinian version as if there had been a global dynamics. However, the resulting global description falsifies the actual material nature of the dynamics. (shrink)

The modern materialist approach to life has conspicuously failed to explain such central mind-related features of our world as consciousness, intentionality, meaning, and value. This failure to account for something so integral to nature as mind, argues philosopher Thomas Nagel, is a major problem, threatening to unravel the entire naturalistic world picture, extending to biology, evolutionary theory, and cosmology. Since minds are features of biological systems that have developed through evolution, the standard materialist version of evolutionary biology is fundamentally incomplete. (...) And the cosmological history that led to the origin of life and the coming into existence of the conditions for evolution cannot be a merely materialist history, either. An adequate conception of nature would have to explain the appearance in the universe of materially irreducible conscious minds, as such. Nagel's skepticism is not based on religious belief or on a belief in any definite alternative. In Mind and Cosmos, he does suggest that if the materialist account is wrong, then principles of a different kind may also be at work in the history of nature, principles of the growth of order that are in their logical form teleological rather than mechanistic. In spite of the great achievements of the physical sciences, reductive materialism is a world view ripe for displacement. Nagel shows that to recognize its limits is the first step in looking for alternatives, or at least in being open to their possibility. (shrink)

The aim of this paper is to paraphrase Theda Skocpol’s theory of social revolutions with the use of the conceptual apparatus of non-Marxian historical materialism. In the successive sections of this paper, the concepts of modernization, the nature of state power, an agrarian bureaucracy, and the mechanism of a victorious revolution are paraphrased. This paraphrase makes it possible to distinguish two kinds of agrarian bureaucracies, each resulting in social revolutions with different outcomes. A victorious revolution led to successful modernization (...) in the case of an economic agrarian bureaucracy, but not in the case of a political agrarian bureaucracy. (shrink)

Glenn Pearce, labels the identification of the firing of one's pain centres in the brain with feeling pain ‘a naive view,’ the refutation of which cannot much threaten any serious version of materialism. But in fact at least a dozen proponents of contemporary materialism have already hypothesized the identification of feeling pain with activation of a specific neural mechanism, although they picked the wrong mechanism, namely C-fibres. Just to take a recent example, James Cornman and Keith Lehrer, trying (...) to get around the objection to the identity theory that the language of neural processes and the language of feeling pains belong to different linguistic categories, suggest that the materialist could devise a new term to refer to the same entity across categories: ‘fibain.’They write,He would then claim that there are fibains, that is, entities with those properties usually associated with pains, and also with the properties usually associated with firing C-fibers. He can, then, avoid category mistakes by saying that what are thought to be pains and what are thought to be firing C-fibers are really fibains. (shrink)

Most theisms and atheisms share an assumption about what divine action would look like; if God is real and acts in the world, then God acts through intervention, invading the mechanistic world as an alien agent. Whitehead's Religious Thought takes dead aim at this contention, arguing that such conceptions of divine intervention emerge from and reinforce a problematic dualism that permeates western theological discourse. Throughout his text Daniel A. Dombrowski links dualistic conceptions of human experience with metaphysical dualism, but (...) also argues that materialistic or mechanistic conceptions of the universe all presume the same basic constituents: machines and ghosts. Materialism rids the world of ghosts and... (shrink)

Viktor Hamburger was a developmental biologist interested in the ontogenesis of the vertebrate nervous system. A student of Hans Spemann at Freiburg in the 1920s, Hamburger picked up a holistic view of the embryo that precluded him from treating it in a reductionist way; at the same time, he was committed to a materialist and analytical approach that eschewed any form of vitalism or metaphysics. This paper explores how Hamburger walked this thin line between mechanistic reductionism and metaphysical vitalism (...) in light of his work on the factors influencing growth of neurons into limb buds, and the discovery of nerve growth factor, work carried out with Rita Levi-Montalcini and Stanley Cohen. (shrink)

_René Descartes proposed an interactive dualism that posits an interaction between the_ _mind of a human being and some of the matter located in his or her brain. Isaac Newton_ _subsequently formulated a physical theory based exclusively on the material/physical_ _part of Descartes’ ontology. Newton’s theory enforced the principle of the causal closure_ _of the physical, and the classical physics that grew out of it enforces this same principle._ _This classical theory purports to give, in principle, a complete deterministic account (...) of the_ _physically described properties of nature, expressed exclusively in terms of these_ _physically described properties themselves. Orthodox contemporary physical theory_ _violates this principle in two separate ways. First, it injects random elements into the_ _dynamics. Second, it allows, and also requires, abrupt probing actions that disrupt the_ _mechanistically described evolution of the physically described systems. These probing_ _actions are called Process 1 interventions by von Neumann. They are psycho-physical_ _events. Neither the content nor the timing of these events is determined either by any_ _known law, or by the afore-mentioned random elements. Orthodox quantum mechanics_ _considers these events to be instigated by choices made by conscious agents. In von_ _Neumann’s formulation of quantum theory each such intervention acts upon the state of_ _the brain of some conscious agent. Thus orthodox von Neumann contemporary physics_ _posits an interactive dualism similar to that of Descartes. But in this quantum version the_ _effects of the conscious choices upon our brains are controlled, in part, by the known_ _basic rules of quantum physics. This theoretically specified mind-brain connection allows_ _many basic psychological and neuropsychological findings associated with the apparent_ _physical effectiveness of our conscious volitional efforts to be explained in a causal and_ _practically useful way.. (shrink)

René Descartes proposed an interactive dualism that posits an interaction between the mind of a human being and some of the matter located in his or her brain. Isaac Newton subsequently formulated a physical theory based exclusively on the material/physical part of Descartes’ ontology. Newton’s theory enforced the principle of the causal closure of the physical, and the classical physics that grew out of it enforces this same principle. This classical theory purports to give, in principle, a complete deterministic account (...) of the physically described properties of nature, expressed exclusively in terms of these physically described properties themselves. Orthodox contemporary physical theory violates this principle in two separate ways. First, it injects random elements into the dynamics. Second, it allows, and also requires, abrupt probing actions that disrupt the mechanistically described evolution of the physically described systems. These probing actions are called Process 1 interventions by von Neumann. They are psycho-physical events. Neither the content nor the timing of these events is determined either by any known law, or by the afore-mentioned random elements. Orthodox quantum mechanics considers these events to be instigated by choices made by conscious agents. In von Neumann’s formulation of quantum theory each such intervention acts upon the state of the brain of some conscious agent. Thus orthodox von Neumann contemporary physics posits an interactive dualism similar to that of Descartes. But in this quantum version the effects of the conscious choices upon our brains are controlled, in part, by the known basic rules of quantum physics. This theoretically specified mind-brain connection allows many basic psychological and neuropsychological findings associated with the apparent physical effectiveness of our conscious volitional efforts to be explained in a causal and practically useful way.. (shrink)

The subject of this study is the problem of the failure of attempts by the scientific community to come to a common understanding of what exactly information can be as something encoded into material structures and moved along with them. At the same time, the following aspects of this problem are considered in detail: what is the immediate cause of the information problem; what are the objective and subjective prerequisites for its appearance; why the unresolved nature of this problem does (...) not interfere with the creation and development of communication systems, control and other "smart" devices; is there any general guideline for finding solutions to such problems, and what is it; what role did the philosophy of information play in turning the problem of information from a private scientific problem into a problem of the ideological level. The main results of the conducted research are as follows: the immediate cause of the information problem has been identified and a comprehensively substantiated solution to this problem has been given; it has been revealed that the incompleteness of the materialistic theory of cognition has become a fertile ground for the appearance of this problem; the circumstances that prevented its completion have been identified; the natural mechanism of control and cognition has been revealed, as a result of which the materialistic theory of cognition has been further developed the source of the ideal in the material world is revealed; it is shown that the mechanistic idea of information coding made the concept of information incompatible with the presence of any objective content; it is revealed what is actually hidden behind the words about information coding and its measurement; the nature of signals and signs is revealed; a kind of bias of the philosophy of information and a general error is revealed all known concepts of information. (shrink)

Recent developments regarding the pharmacology of psychoactive substances are significant for treating depressions or opioid addictions. Current theories, hypotheses, and models of drug effects assume a cause–effect narrative, which is based on a stimulus/response mechanism. These narratives prioritize effects rather than conscious experiences. In this sense, drug experiences are quickly subsumed into common categories and codes of biological determinism. If subjective experiences are in the focus of the research, it quickly becomes a link to mystical, spiritual, or transcendental narratives. These (...) classifications lead to epistemological doublets (Gadamer). In this article, psychedelic experiences of drug users are analyzed in the frame of the pharmaco-analysis by Deleuze/Guattari. These framed psychedelic experiences are interpreted by means of a non-philosophical approach through philo-fictions (Laruelle), i.e., contradictory assumptions and hyperspeculations. In this respect, the aim of this article is to bring philo-fictions in relation to psychedelic experiences and to discuss them with models of information science, quantum mechanics, new materialism, and the philosophy of immanence. The result will be an open synthesis, with the assumption of further reflections on the agency, immanence, and the wholeness of matter. (shrink)

The reversibility problem (better known as the reversibility objection) is usually taken to be an internal problem in the kinetic theory of gases, namely the problem of how to account for the second law of thermodynamics within this theory. Historically, it is seen as an objection that was raised against Boltzmann's kinetic theory of gases, which led Boltzmann to a statistical approach to the kinetic theory, culminating in the development of statistical mechanics. In this paper, I show that in the (...) late nineteenth century, the reversibility problem had a much broader significance - it was widely discussed and certainly not only as an objection to Boltzmann's kinetic theory of gases. In this period, there was a conflict between mechanism and irreversibility in physics which was tied up with central issues in philosophy of science such as materialism, empiricism and the need for mechanistic foundations of physical theories, as well as with concerns about the heat death of the universe. I discuss how this conflict was handled by the major physicists of the period, such as Maxwell, Kelvin, Duhem, Poincaré, Mach and Planck, as well as by a number of lesser-known authors. (shrink)

Viktor Hamburger was a developmental biologist interested in the ontogenesis of the vertebrate nervous system. A student of Hans Spemann at Freiburg in the 1920s, Hamburger picked up a holistic view of the embryo that precluded him from treating it in a reductionist way; at the same time, he was committed to a materialist and analytical approach that eschewed any form of vitalism or metaphysics. This paper explores how Hamburger walked this thin line between mechanistic reductionism and metaphysical vitalism (...) in light of his work on the factors influencing growth of neurons into limb buds, and the discovery of nerve growth factor, work carried out with Rita Levi-Montalcini and Stanley Cohen. (shrink)

This paper draws on the cultural-materialist paradigm articulated by Raymond Williams to offer a radical historicisation of identity and identity-politics in capitalist societies. A keywords analysis reveals surprisingly that identity, as it is elaborated in the familiar categories of personal and social identity, is a relatively novel concept in Western thought, politics and culture. The claim is not the standard one that people’s ‘identities’ became more important and apparent in advanced capitalist societies, but that identity itself came to operate as (...) a new and key mechanism for construing, shaping and narrating experiences of selfhood and grouphood in this period. From a cultural-materialist perspective, the emergence and evolution of this idea of identity can only be properly understood in relation to the social contexts of its use, namely, the new contexts of consumption of capitalist societies, and the development of new forms of group-based struggle from the 1960s. What the analysis shows is that it was the commercialisation and politicisation of older essentialist understandings of selfhood and grouphood in these contexts that has given rise to the concepts of personal and social identity as we know them today.By exploring the material conditions that have given rise to the contemporary powerful attachment to ‘identity’, this paper offers a new point of departure from which to pursue many issues of concern to critical theorists and radical activists today, including the conflict over identity politics in radical circles, the historical and social processes behind their development and at least partial co-option, and their relation to neoliberal political-economic formations today. (shrink)