Along the same line as that in Ono (Ann Pure Appl Logic 161:246–250, 2009), a proof-theoretic approach to Glivenko theorems is developed here for substructural predicate logics relative not only to classical predicate logic but also to arbitrary involutive substructural predicate logics over intuitionistic linear predicate logic without exponentials QFLe. It is shown that there exists the weakest logic over QFLe among substructural predicate logics for which the Glivenko theorem holds. Negative translations of substructural predicate logics are studied by using (...) the same approach. First, a negative translation, called extended Kuroda translation is introduced. Then a translation result of an arbitrary involutive substructural predicate logics over QFLe is shown, and the existence of the weakest logic is proved among such logics for which the extended Kuroda translation works. They are obtained by a slight modification of the proof of the Glivenko theorem. Relations of our extended Kuroda translation with other standard negative translations will be discussed. Lastly, algebraic aspects of these results will be mentioned briefly. In this way, a clear and comprehensive understanding of Glivenko theorems and negative translations will be obtained from a substructural viewpoint. (shrink)

Introduction Good quality of care is dependent on nurses’ strong clinical skills and moral competencies, as well. While most nurses work with high moral standards, the moral performance of some nurses in some organizations shows a deterioration in their moral sensitivity and actions. The study reported in this paper aimed to explore the experiences of nurses regarding negative changes in their moral practice. Materials and methods This was a qualitative study utilizing an inductive thematic analysis approach, which was conducted from (...) February 2017 to September 2019. Twenty-five nurses participated in semi-structured interviews. Results The main theme that emerged from our analysis was one of moral neutralization in the context of an unethical moral climate. We found five sub-themes, including: feeling discouraged; normalization; giving up; becoming a justifier; and moral indifference. Conclusions Unethical moral climates in health organizations can result in deterioration of morality in nurses which can harm both patients and health systems. Some unethical behaviors in nurses can be explained by this process. (shrink)

Religion and culture play a central role in building harmonious relations between followers of different religions, both within the nuclear family and in the extended family. This study examines the revitalisation of religious moderation with a cultural approach in strengthening tolerance. Data was obtained qualitatively from in-depth interviews and observations of families of different religions, religious leaders, traditional leaders, and other relevant informants. The research findings show that the family institution is the most crucial place in carrying out moderate religious (...) culturalisation through the local wisdom values of kasiuluran [kinship], tengko situru [togetherness], and karapasan [tenacity]. Institutionally, traditional leaders, religious leaders, and clans in Tongkonan encourage peace in society, both in traditional and religious activities. Meanwhile, religious celebrations, traditional ceremonies, and community activities are occasions to socialise and interact by placing a firm tolerance for religious differences. CONTRIBUTION: This study contributes to the realisation of tolerance through the application of moderate religious values and local wisdom that the world needs today. Strengthening inter-religious relations is very important because the position of religion is complex and sensitive. This contribution is crucial in the midst of the rampant issue of radicalism in Indonesia lately. (shrink)

Religion and culture play a central role in building harmonious relations between followers of different religions, both within the nuclear family and in the extended family. This study examines the revitalisation of religious moderation with a cultural approach in strengthening tolerance. Data was obtained qualitatively from in-depth interviews and observations of families of different religions, religious leaders, traditional leaders, and other relevant informants. The research findings show that the family institution is the most crucial place in carrying out moderate religious (...) culturalisation through the local wisdom values of kasiuluran [kinship], tengko situru [togetherness], and karapasan [tenacity]. Institutionally, traditional leaders, religious leaders, and clans in Tongkonan encourage peace in society, both in traditional and religious activities. Meanwhile, religious celebrations, traditional ceremonies, and community activities are occasions to socialise and interact by placing a firm tolerance for religious differences. CONTRIBUTION: This study contributes to the realisation of tolerance through the application of moderate religious values and local wisdom that the world needs today. Strengthening inter-religious relations is very important because the position of religion is complex and sensitive. This contribution is crucial in the midst of the rampant issue of radicalism in Indonesia lately. (shrink)

BackgroundDiscrimination in health care is an international challenge and a serious obstacle to justice and equality in health.Research objectiveThe purpose of this study was to design a grounded theory of discrimination in health care based on the experiences and perceptions of Iranian healthcare providers and patients.Research designThis qualitative study was conducted using by the grounded theory method.Participants and research contextData were collected through semi-structured interviews with 18 healthcare providers including 11 nurses, two physicians, two nurse’s assistants, and three patients in (...) two general hospitals in Tehran, Iran. Participants were selected through purposeful sampling and analyzed simultaneously using the Corbin and Strauss (2015) approach.Ethical considerationsThe study was approved by the Research Ethics Committee of the University of Social Welfare and Rehabilitation Sciences (Ethics code: IR.USWR.REC.1398.023). Also, after explaining the objectives of the study, all the participants completed and signed the written consent form.FindingsThe “culture of discrimination” was the study’s core category, reflecting the nature of discrimination in health care. The theory of “culture of discrimination in health care” is the result of five main categories: “individual social stimuli,” “culture of discrimination,” “unintentional discrimination,” “conflict with discrimination,” and “dissatisfaction with discriminatory behavior.” These categories cover the underlying factors, strategies, and outcomes of the discrimination process in health care.DiscussionThe results of the study showed that nurses and other health care providers experience unintentional discrimination. Unintentional discrimination refers to discriminatory behaviors and practices of health care providers.ConclusionThe theory of culture of discrimination in health care can be used as a practical guide to describe and understand the role of health care providers, especially nurses. Further studies with a quantitative approach to applying this theory in medical settings are recommended. (shrink)

Religious moderation is a crucial issue, along with religious and cultural values that develop in society. Religious moderation’s success will significantly determine millennial Muslim youth’s tolerant attitudes, mediated by intellectual humility. This study aimed to identify and design a model of religious moderation on tolerance by mediating intellectual humility. The research used mixed methods; data analysis used NVivo 12 Plus (software by QSR International), to compile variable nominations; and Partial Least Squares - Structural Equation (PLS-SEM) creates research models. There were (...) 350 Indonesian youth informants in the study, which used interviews and focus group discussions. The results showed that religious moderation in youth, including national commitment, antiviolence and acceptance of local culture, can strengthen tolerance, mediated by intellectual humility. The tolerant attitude shows high and stable data and confirms the strengthening of religious moderation in young people. From the identification, a model of religious moderation in youth was designed and revised, and the results have met all the requirements for modelling so that it can be continued for testing.Contribution: This research provides essential assistance in implementing religious moderation for young people, which is currently the most prevalent issue in Indonesia. The world needs a moderate religious attitude to become a middle ground for various religious and cultural differences among people globally. (shrink)

Strengthening Muslim-Christian relations is very important for a nation such as Indonesia that has plurality in terms of tribes, ethnicity and religion. This study aims to analyse the role of Muslim women who live in a pluralistic socio-religious situation. This is a qualitative research that uses purposive sampling to determine the informants. The approach used by the Discovering Cultural Themes model is to understand the symptoms of the many themes, cultures, values and cultural symbols. Data analysis was conducted by using (...) software for qualitative research, which is needed in managing data found from the field, in this case, nVivo Basic 12.00 for Windows. The results show that Muslim women translate justice, empathy and rationality in religion by building relationships with other religions. This attitude is part of Islamic teachings that contain moderate, accommodating and tolerant aspects. In addition, culture has encouraged women to blend in and form egalitarian equality in the social and cultural realm. The culture of generosity and mutual help has become a tradition both in religious and customary activities. CONTRIBUTION: This article provides an insight into the contribution of Muslim women in strengthening Muslim-Christian relations. This agenda is very important because Islam and Christianity have the largest adherents in Indonesia. This contribution is very important and crucial in the midst of radicalism issues in Indonesia lately. (shrink)

La relation est au coeur de l'existence individuelle et les multiplicités, que déterminent les différents rapports pratiques, affectifs, sociaux et politiques, sont coextensives à l'invention continue de l'individualité par elle-même. Le présent essai veut rendre compte de la constitution, à partir de la seule activité des individus, des diverses formes d'existence et d'organisation que peut revêtir un ensemble pratique : rassemblements, dispositifs collectifs, réseaux et systèmes, associations et communautés plus ou moins étendues et diversement intégrées, institutions et Etats, sans oublier (...) les conflits et les luttes, avec leur développement historique. Affectée par des phénomènes de domination, la multiplicité reçoit la structure passive de l'union en altérité, comme si la liberté en venait à réaliser, malgré elle, la transmutation de la puissance singulière en impuissance. Mais une multiplicité active peut aussi se constituer en résistant à la servitude et en rompant avec l'être sériel : elle s'affirme alors dans l'expérience subjective du groupe, avec l'apparition du pouvoir normatif et critique appartenant à une multitude libre, qui crée de nouvelles formes de la vie sociale. (shrink)

Cross-cultural sex differences in mobility and harm avoidance have been widely reported, often emphasizing fitness benefits of long-distance travel for males and high costs for females. Data emerging from adults in small-scale societies, however, are challenging the assumption that female mobility is restricted during reproduction. Such findings warrant further exploration of the ontogeny of mobility. Here, using a combination of machine-learning, mixed-effects linear regression, and GIS mapping, we analyze range size, daily distance traveled, and harm avoidance among Hadza foragers during (...) middle childhood and adolescence. Distance traveled increased with age and, while male adolescents had the longest daily ranges, average daily distance traveled by each sex was similar. We found few age- or sex-related patterns in harm-avoidant responses and a high degree of individual variation. When queried on the same issues, children and their parents were often in alignment as to expectations pertaining to harm avoidance, and siblings tended to behave in similar ways. To the extent that sex differences in mobility did emerge, they were associated with ecological differences in physical threats associated with sex-specific foraging behaviors. Further, we found no strong association between harm avoidance and mobility. Young Hadza foragers of both sexes are highly mobile, regardless of how harm avoidant they are. Taken together, our findings indicate that the causal arrows between harm avoidance and mobility must be evaluated in ecologically specific frameworks where cultural expectations of juvenile mobility can be contextualized. (shrink)

We were delighted to be asked by the editors of the American Journal of Bioethics to provide this editorial in response to Dr. Ariane Lewis’s paper “An Overview of Ethical Issues Raised by Medicole...

This book is a theoretically and historically informed exploration of 'secularism' in Muslim contexts. It does this through a critical assessment of an influential tradition of thinking about Islam and secularism, derived from the work of anthropologist Talal Asad and his followers. The study employs the tools of comparative historical sociology and sociology of knowledge to engage with the assumptions of Asadian theory. Ultimately, Enayat argues against nativist assertions drawn from the experience of Western modernity and provides a qualified defense (...) of secularism. (shrink)

The study aim was 2-fold (i) to describe and compare the in-season variations of acute: chronic workload ratio (ACWR) coupled, ACWR uncoupled, and exponentially weighted moving average (EWMA) through session-rated perceived exertion (s-RPE), total distance (TD), high-speed running distance (HSRD), and sprint distance across different periods of a professional soccer season (early, mid, and end-season) between starters and non-starters; (ii) to analyze the relationship the aforementioned measures across different periods of the season for starters and non-starters. Twenty elite soccer players (...) (mean ± SD age, 29.4 ± 4.4 y; height, 1.8 ± 0.1 m; and body mass, 74.8 ± 2.3 kg). They were divided into starter and non-starter groups and were evaluated for 20 weeks. ACWR had general changes throughout the season. At the beginning and end of the mid-season, the highest ACWR was observed in three parameters: s-RPE, TD, and HSRD. ACWR and EWMA through sprint distance were higher at the beginning of the early-season than at any other time of the season.The ACWR coupled of s-RPE shows a significant higher value for non-starters than starters (p = 0.015;g = −1.01 [−1.98, −0.09]) and the ACWR coupled of TD shows a significant higher value for starters than non-starters in early-season (p < 0.01;g = 3.01 [1.78, 4.46]) and shows a significant higher value for non-starters than starters in mid-season (p < 0.01;g = −2.52 [−3.83, −1.39]), and end-season (p < 0.01;g = −2.57 [−3.89, −1.43]). While the EWMA of TD shows a significant higher value for starters than non-starters in early-season (p < 0.01;g = 2.25 [1.17, 3.49]) and mid-season (p < 0.01;g = 2.42 [1.31, 3.71]), and shows a significant higher value for non-starters than starters in end-season (p < 0.01;g = −2.23 [−3.47, −1.16]). Additionally, we found some correlations between external and internal load measures during three periods of the in-season. The study’s main finding was that the indexes of ACWR and EWMA were useful to detect differences between period and between playing status with the exception for the sprint variable. In addition, the necessary work for non-starter players’ improvement is not done during training, and these players lose their readiness as the season progresses. Consequently, these players perform poorly during the match. Therefore, coaches and their staff should consider devising new activities to keep non-starter players physically fit. This deficit must be accounted for in training because they compete in fewer matches and have less burden than starters. (shrink)

This study describes the weekly variations of well-being ratings relative to fatigue, stress, delayed-onset muscle soreness, sleep quality, and Hooper questionnaire throughout the season. In addition, the well-being variables for the playing position in different moments of the season were discussed. Twenty-one elite young soccer players U17 took part in this study. From the beginning of the pre-season, well-being status was monitored daily by the HQ method throughout 36 weeks, including four periods: pre-season, early-season, mid-season, and end-season. Players trained at (...) least 3 times per week throughout the season. The main outcome was that, in weeks 33 and 28, the highest [wFatigue: 15.85 ± 3.38 arbitrary units ; wHQ: 48.86 ± 9.23 AU] and the lowest wFatigue and wHQ occurred, respectively, although the lowest level of wDOMS happened in week 28, while the highest wDOMS was observed in week 5. The highest wSleep and wStress were observed in weeks 8 and 34, respectively, while the lowest wSleep and wStress were marked in week 29 coincidentally. In the HQ between every weekday, except recovery day, and the day of the match, considerable highest HQ was only revealed in 2 days after MD in contrast to overall team comparison. In the present study, we observed that the well-being changes between different phases of the season as well as between weeks and days of the week with the MD are significant. These results provide a great point of view for coaches and practitioners about well-being variations over a season in elite youth soccer level. As a result, coaches will be more aware about non-functional overreaching and taking measures to prevent it. (shrink)

Injuries in professional soccer are a significant concern for teams, and they are caused amongst others by high training load. This cohort study describes the relationship between workload parameters and the occurrence of non-contact injuries, during weeks with high and low workload in professional soccer players throughout the season. Twenty-one professional soccer players aged 28.3 ± 3.9 yrs. who competed in the Iranian Persian Gulf Pro League participated in this 48-week study. The external load was monitored using global positioning system (...) and the type of injury was documented daily by the team's medical staff. Odds ratio and relative risk were calculated for non-contact injuries for high- and low-load weeks according to acute, chronic, acute to chronic workload ratio, and AW variation values. By using Poisson distribution, the interval between previous and new injuries were estimated. Overall, 12 non-contact injuries occurred during high load and 9 during low load weeks. Based on the variables ACWR and Δ-AW, there was a significantly increased risk of sustaining non-contact injuries during high-load weeks for ACWR, and Δ-AW. Finally, the expected time between injuries was significantly shorter in high load weeks for ACWR [1.25 vs. 3.33, rate ratio time ] and Δ-AW respectively, compared to low load weeks. The risk of sustaining injuries was significantly larger during high workload weeks for ACWR, and Δ-AW compared with low workload weeks. The observed high OR in high load weeks indicate that there is a significant relationship between workload and occurrence of non-contact injuries. The predicted time to new injuries is shorter in high load weeks compared to low load weeks. Therefore, the frequency of injuries is higher during high load weeks for ACWR and Δ-AW. ACWR and Δ-AW appear to be good indicators for estimating the injury risk, and the time interval between injuries. (shrink)

Source: Author: Mohsen Mehrara, Yazdan Gudarzi Farahani, Farzan Faninam, Abbas Rezazadeh Karsalari This paper examines the relationship between stock market index and macroeconomic policies on Iran's economy using quarterly data in the period 1999-2013. This study employed cointegration test and vector autoregressive models to examine relationships between the stock market index and the macroeconomic variables. The empirical results reveal that a positive money shock can increase stocks return. According to impulse responses, the government expenditure had a slight impact on (...) stocks return in the short term. But the government expenditure has a positive effect on exchange index in long run. Also the effect of taxes on the stock's price index is negative, so that it reaches its maximum level after the third lag and then alleviates. The GDP shock has positive effect on the stock's price index. Increase in production level leads to increase in earnings and profitability, leading to a positive response from stocks index. Therefore the results showed that the macroeconomic variables such as inflation, exchange rate and GDP have significant effects on Tehran exchange price index. So the hypothesis that the improving economic factors can have a useful role in the booming capital market is confirmed. Also the effect of fiscal policy factors such as tax revenues and government expenditures is more than monetary policy factors on stock returns. ]]>. (shrink)

La théocratie hébraïque est un système unique de croyances, de conduites et de rites, qui a favorisé la cohésion du peuple et le consentement aux règles de la vie commune. Il est vrai que le régime dit théocratique des Hébreux n’est pas une simple illusion rétrospective, propre à tous ceux qui veulent appuyer le pouvoir politique sur l’illusion d’une intervention directe de Dieu dans les affaires de l’État. En effet, la théocratie juive, qui a effectivement existé dans les limites de (...) deux siècles environ, ne déroge pas, dans l’analyse qu’en livre Spinoza, à la thèse que tout pouvoir politique est immanent à la puissance de la multitude, puissance dont il provient et puissance à laquelle il conduit. Le pouvoir qu’a institué Moïse, ni monarchique, ni aristocratique, ni populaire, est une forme faible de démocratie instituée, où le pouvoir, dit appartenir à Dieu, n’appartient de fait à aucun homme. C’est en ce sens que la Loi apparaît comme l’altérité des prescriptions mêmes de la raison, dans des conditions historiques déterminées. (shrink)

For the average person, genetic testing has two very different faces. The rise of genetic testing is often promoted as the democratization of genetics by enabling individuals to gain insights into their unique makeup. At the same time, many have raised concerns that genetic testing and sequencing reveal intensely personal and private information. As these technologies become increasingly available as consumer products, the ethical, legal, and regulatory challenges presented by genomics are ever looming. Assembling multidisciplinary experts, this volume evaluates the (...) different models used to deliver consumer genetics and considers a number of key questions: How should we mediate privacy and other ethical concerns around genetic databases? Does aggregating data from genetic testing turn people into products by commercializing their data? How might this data reduce or exacerbate existing healthcare disparities? Contributing authors also provide guidance on protecting consumer privacy and safety while promoting innovation. (shrink)

The management control system aids administrators in guiding a business toward its organizational plans; as a result, management control is primarily concerned with the execution of the plan and plans. Financial and nonfinancial criteria are used to create management control systems. The financial element focuses on net income, earnings, and other financial metrics. The two components of leadership strategy in this study are cost and differentiation, which highlight the strategy of differentiation in attaining higher quality due to the robust strategy’s (...) attention on a particular area of the company. In this study, we presented a novel method named deep interaction neural network to predict the performance of the manufacturing companies based on their leading competitors using features cost leadership and differentiation strategies. Moreover, the management control system is classified into two financial and nonfinancial factors based on machine learning methods. Based on the results, the presented factors can accurately estimate the company’s performance based on management control criteria with a 93.48% R-square. Moreover, it can be seen that the DT method is presented with higher classification performance values. (shrink)

This paper examines disagreement strategies employed by speakers of Jordanian Spoken Arabic with a view to finding out whether variables like gender and social status affect the linguistic choices and disagreement strategies they employ. The subjects are 28 Jordanian Arabic-speaking students at the University of Jordan. The researchers analyze the students’ interactional recorded responses to a set of stimuli included in an oral discourse completion task prepared for this purpose. The ODCT comprises six scenarios in which the respondent is requested (...) to disagree with two peers, two higher-status interlocutors and two lower-status interlocutors. The findings show that male and female subjects’ disagreement strategies tend to be influenced by the topic under discussion rather than by the gender and status of their interlocutor. However, some topics are found to be more provocative to females than to males. (shrink)

According to a well-established view of desire satisfaction, a desire that p is satisfied iff p obtains. Call this the 'standard view'. The standard view is purely semantic, which means the satisfaction condition of desires is placed in the truth of the embedded proposition that indicates the content of the desire. This paper aims to defend the standard view against two frequently discussed problems: the problem of underspecification and desires conditional on their own persistence. The former holds that the standard (...) view cannot capture the specific ways of desire satisfaction. The latter holds that the standard view does not provide sufficient conditions for the satisfaction of desires conditional on their own persistence. To address the first problem, I will disambiguate different interpretations of desire ascriptions using de re/de dicto distinction. My argument to address the second problem rests on the disambiguation of different senses of satisfaction: semantic and agent. (shrink)

Researchers studying human behavioral genetics have made significant scientific progress in enhancing our understanding of the relative contributions of genetics and the environment in observed variations in human behavior. Quickly outpacing the advances in the science are its applications in the criminal justice system. Already, human behavioral genetics research has been introduced in the U.S. criminal justice system, and its use will only become more prevalent. This essay discusses the recent historical use of behavioral genetics in criminal cases, recent advances (...) in two gene variants of particular interest in the criminal law, MAOA and SLC6A4, the recent expert testimony on behalf of criminal defendants with respect to these two gene variants, and the future direction of behavioral genetics evidence in criminal cases. (shrink)

In the new era of technology, internet turns to be one of the main sources of information, since it is considered cheaper and easier to use. Hence in tourism, two main pull factors influencing potential tourist to visit a destination are recognized as nature and culture which a destination offers. The acceptance of culture as one of the important factors in tourists’ motivation, heritage sites become popular in many countries especially those which are nominated as world heritage sites. This paper (...) is to analyze the condition of available online information about George Town world heritage spots (Penang, Malaysia). As far as heritage is one of the products of tourism and tourism, on the other hand, is a big help for sustainability of heritage sites, providing sufficient information about tourism heritage sites as a promotional key is very important. Top ten tourism websites were chosen and content analysis was performed to find the current situation of those websites. By recognizing heritage as tangible and intangible, the result shows that although the intangible heritages need more concern in sustainability matter, but the information about them are not as complete as the tangible ones. Lack of proper information was seen in most websites and the focus of information was more on tangible heritage and among intangible heritage, the main focus was on food. To support the result of analysis, in-dept interviews were conducted by couple of heritage offices in the city. The main reason behind the lack of sufficient information about intangible heritage seems to be the lack of complete list of them and moreover, promoting this division of heritage needs negotiation with the local residence involving in those activities. The paper suggests providing a complete list of George Town world heritage as far as some of them are disappearing lately, and keeping this valuable world heritage sustainable for next generation needs detailed study and completing the list as soon as possible. In this regard those intangible heritages which are in hazard of disappearing can be maintained by the effort of key holders of the field. Moreover, providing the mentioned list helps the information providers, especially related websites to focus equally on tangible and intangible George Town world heritage. (shrink)

Topological indices are of incredible significance in the field of graph theory. Convex polytopes play a significant role both in various branches of mathematics and also in applied areas, most notably in linear programming. We have calculated some topological indices such as atom-bond connectivity index, geometric arithmetic index, K-Banhatti indices, and K-hyper-Banhatti indices and modified K-Banhatti indices from some families of convex polytopes through M-polynomials. The M-polynomials of the graphs provide us with a great help to calculate the topological indices (...) of different structures. (shrink)

A correction to this paper has been published: https://doi.org/10.1007/s12110-021-09403-x.

During the early Cambrian period metazoan life forms diverged at an accelerated rate to occupy multiple ecological niches on earth. A variety of explanations have been proposed to address this major evolutionary phenomenon termed the “Cambrian explosion.” While most hypotheses address environmental, developmental, and ecological factors that facilitated evolutionary innovations, the biological basis for accelerated emergence of species diversity in the Cambrian period remains largely conjectural. Herein, we posit that morphogenesis by self‐organization enables the uncoupling of genomic mutational landscape from (...) phenotypic diversification. Evidence is provided for a two‐tiered interpretation of genomic changes in metazoan animals wherein mutations not only impact upon function of individual cells, but also alter the self‐organization outcome during developmental morphogenesis. We provide evidence that the morphological impacts of mutations on self‐organization could remain repressed if associated with an unmet negative energetic cost. We posit that accelerated morphological diversification in transition to the Cambrian period has occurred by emergence of dormant (i.e., reserved) morphological novelties whose molecular underpinnings were seeded in the Precambrian period. (shrink)

ObjectivesThe breast cancer stigma affects Health-related quality of life, while general resilience resources, namely, sense of coherence, social support, and coping skills, are thought to alleviate this effect. The study aimed to explore the mediating/moderation role of GRRs in the relationship between stigma and HRQoL and its dimensions in Iranian patients with breast cancer.MethodsIn this cross-sectional study, Stigma Scale for Chronic Illness 8-item version, SOC-13, Medical Outcome Survey- Social Support Scale, Brief COPE, and Functional Assessment of Cancer Therapy-Breast were investigated (...) in a convenience sample of Iranian women with confirmed non-metastatic breast cancer. Following the establishment of correlations using Pearson’s correlation, single and parallel mediation analysis and moderation analysis were conducted to determine the extent to which each GRR might be impacted by stigma or decrease the adverse impact of stigma on HRQoL.ResultsAn analysis of 221 women with the mean age of 47.14 showed that stigma was negatively correlated to all HRQoL’s dimensions, SOC, social support, and the bulk of coping skills. In the single mediation analysis, stigma affected all facets of SOC, all subscales of social support, and positive reframing, which partially reduced breast cancer HRQoL. Stigma affects general HRQoL through damaging meaningfulness, social support, and positive reframing. Meaningfulness was marked as the most impacted GRR in terms of all domains of HRQoL. In parallel mediation, reduced meaningfulness, total social support, and positive reframing were highlighted as the pathways of diminished breast cancer HRQoL. Moderation analysis indicated the higher levels of humor, behavioral disengagement, and use of instrumental support behaviors to be functional in protecting different dimensions of HRQoL, while the results were mixed for venting, especially in patients with mastectomy surgery.ConclusionWhile GRRs may be impacted by stigma, they exert a relatively small protective effect against the impact of stigma on HRQoL. This study provides some novel findings, but longitudinal studies are needed to further verify these before any causal conclusion or recommendations for health policy can be drawn. (shrink)

The rise of neurotechnologies, especially in combination with artificial intelligence (AI)-based methods for brain data analytics, has given rise to concerns around the protection of mental privacy, mental integrity and cognitive liberty – often framed as “neurorights” in ethical, legal, and policy discussions. Several states are now looking at including neurorights into their constitutional legal frameworks, and international institutions and organizations, such as UNESCO and the Council of Europe, are taking an active interest in developing international policy and governance guidelines (...) on this issue. However, in many discussions of neurorights the philosophical assumptions, ethical frames of reference and legal interpretation are either not made explicit or conflict with each other. The aim of this multidisciplinary work is to provide conceptual, ethical, and legal foundations that allow for facilitating a common minimalist conceptual understanding of mental privacy, mental integrity, and cognitive liberty to facilitate scholarly, legal, and policy discussions. (shrink)

In May 2023, the world’s first whole-eye and partial-face transplant was performed, representing the first known whole-eye transplant in history and the “only successful combined transplant case of...