ABSTRACT The aim of this article is to determine whether genetic engineering is ever acceptable. The prominent arguments which have been put forward by the opponents of genetic engineering are examined and evaluated. The arguments ‘we should not interfere with nature’, ‘we should not alter the genetic constitution of organisms’, and ‘we should not alter the genetic constitution of organisms to this extent’are found to be inadequate as valid arguments against all genetic engineering. However, it remains a possibility that there (...) is nothing intrinsically unethical about genetic engineering, but that the risks of misuse render the techniques ethically unacceptable. Since universal legislation is not possible, and the risks of genetic engineering are so real, this alone may be sufficient to dismiss all genetic engineering as wrong. (shrink)

Japanese conversational data reveal that Japanese speakers produce, and recipients orient to, smaller units of talk than what the conventional notion of a `turn constructional unit' represents. Unlike TCUs, such units may be grammatically, prosodically and pragmatically incomplete and may happen on the sub-phrasal level of discourse, as Japanese conversationalists prosodically break up even a single semantic constituent with the insertion of an interactional particle. In this article, I give numerous examples of how such practices of separating a segment of (...) talk are not random but are precisely embedded in the sequential organization of talk that participants co-create. I argue that such segmentation contributes to the interactional co-construction of a turn so as to highlight specifically a `move' Within the larger action that is implemented by the TCU. Doing so thereby provides opportunities for the participants to deal with local contingency problems without changing the global level of the pragmatic work of the turn. (shrink)

Sara Ahmed’s enquiry on what it means for sexuality to be lived as oriented from the work Queer Phenomenology inspired the art series ‘A Sexual Series’, based on post-humanist theory and asexual experience. Shapes of performative alter egos materialized from a queer cyborg position of technologically enhanced crip experiences (the strong symbolical constructing process of straightening scoliosis surgery). From being a glitch of the past towards a post-individualist future, the artificial intelligence sexbot is a metaphoric, elevated cyborg drag version of (...) the artist to embody asexuality and queer Otherness. Based on multitudes of CUNTraDICKtions to encourage self-reflection, the series explores the complexities of ob/scene and on/scene performances; the position of a sex positive asexual as well as questions of belonging as a naturally artificial rebel. (shrink)

Working with elders around the world has taught me that those living in grass huts in Africa with children at their feet are often happier than people in assisted‐living homes with a chandelier over their heads. My work in design consultancy and in fifteen years of running a nonprofit, Ibasho, that aims to co‐create socially integrated and sustainable communities that value their elders has allowed me to learn much about how architects and designers can contribute to helping people live a (...) good life in late life. People often need supportive services or other adaptations as they age, but do they really need—or want—the luxury environment few are accustomed to? The challenge for architects and designers is not to create a built environment whose carefully curated facades hide lives of quiet desperation. It is to help elders access the support they need without upending their lives or severing virtually all ties to their communities. (shrink)

There is a growing consensus that the offer of a reasonable compensation for oocyte donation for reproductive treatment is acceptable if it does not compromise voluntary and altruistically motivated donation. However, how to translate this ‘reasonable compensation’ in practice remains unclear as compensation rates offered to oocyte donors between different European Union countries vary significantly. Clinics involved in oocyte donation, as well as those in other medical contexts, might be encouraged in calculating a more consistent and transparent compensation for donors (...) if the elements that constitute a reasonable compensation are explicated. In doing so, lessons can be learnt from living organ donation and medical research participation. Practices in which the elements of a reasonable compensation for the individuals involved have already been more defined in the literature. By means of analogical reasoning, we will outline the different components of a reasonable compensation and subsequently apply these to the context of oocyte donation. We will argue that oocyte donors should first of all be reasonably reimbursed direct expenses related to the donation, without standard remuneration of lost wages. Second, donating oocytes requests a serious time investment, therefore donors are entitled to suitable compensation for their time spent and efforts made. Finally, we will explain that a reasonable compensation consisting of these two components allows for altruism to remain the key value of oocyte donation for reproductive treatment. However, if we acknowledge that donors’ motives are more complex and often include reasons from self-interest, the reasonable compensation may be complemented with modest (non)monetary benefits. (shrink)

We study price formulas suited for empirical research in financial markets in which put–call parity is satisfied. We find a connection between risk and the bid–ask spread. We further study the compatibility of the model with market frictions, and determine market subsets where the Fundamental Theorem of Asset Pricing applies. Finally, we characterize the price formula.

This article is concerned with the history and current state of research activities into medical expert systems (MES) in Japan. A brief review of expert systems' work over the last ten years is provided and here is a discussion on future directions of artificial intelligence (AI) applications in medicine, which we expect the Japanese AI community in medicine (AIM) to undertake.

This paper extends studies on intertextuality into a more explicitly interactional context. I examine the actual process of intertextuality where comedy audiences construct recombinant selves through making sense of various membership categories as well as through making sense of a certain kind of comedy. The examination of this process requires receptive research; however, most studies leave the interpretive process unanalyzed. Conducting both a sequential analysis and a membership categorization analysis will reveal that categories are not “pre-formed” but “per-formed” in situ. (...) To illustrate these points, I report on a receptive study of Local comedy in Hawai‘i. (shrink)

偶然を「運命」として生きる生き方とは何か。九鬼周造が哲学的思索の果てにたどりついた世界観を明らかにする。.

This article analyses the discourse of three prime ministers to explore how each leader identified the political self and constructed and promoted a particular relationship with the voter before the general elections. The outcome indicates the emergence of a new political communication style based on a partyconsumer. Whereas Aso's patronconsumer discourse of both Koizumi and Hatoyama demonstrates the entrepreneurial leadersconsumer model might have played a role in attracting a large number of unorganized voters to Koizumi in 2005 and in turn (...) to Hatoyama in 2009. (shrink)

From ancient times, western civilization has been driven by a trust in scientific progress. Is Science Biology and biogenetics promise spectacular advances, mathematics unfolds new areas of understanding. This work explores some of the possible consequences for society and for the future of science itself.".

It is often assumed that the reaction time of a saccade toward visual and/or auditory stimuli reflects the sensitivities of our oculomotor-orienting system to stimulus saliency. Endogenous factors, as well as stimulus-related factors, would also affect the saccadic reaction time. However, it was not clear how these factors interact and to what extent visual and auditory-targeting saccades are accounted for by common mechanisms. The present study examined the effect of, and the interaction between, stimulus saliency and audiovisual spatial congruency on (...) the SRT for visual- and for auditory-target conditions. We also analyzed pre-target pupil size to examine the relationship between saccade preparation and pupil size. Pupil size is considered to reflect arousal states coupling with locus-coeruleus activity during a cognitive task. The main findings were that the pattern of the examined effects on the SRT varied between visual- and auditory-auditory target conditions, the effect of stimulus saliency was significant for the visual-target condition, but not significant for the auditory-target condition, Pupil velocity, not absolute pupil size, was sensitive to task set, and there was a significant correlation between the pre-saccade absolute pupil size and the SRTs for the visual-target condition but not for the auditory-target condition. The discrepancy between target modalities for the effect of pupil velocity and between the absolute pupil size and pupil velocity for the correlation with SRT may imply that the pupil effect for the visual-target condition was caused by a modality-specific link between pupil size modulation and the SC rather than by the LC-NE system. These results support the idea that different threshold mechanisms in the SC may be involved in the initiation of saccades toward visual and auditory targets. (shrink)

大学、学会、企業、国家などと関わりながら「制度化」の歩みを進めて来た西洋科学。現代に至るまでの歴史を概観した入門書。.