Results for 'E2F family'

995 found
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  1.  6
    DREAM a little dREAM of DRM: Model organisms and conservation of DREAM‐like complexes.Marion Hoareau, Aurore Rincheval-Arnold, Sébastien Gaumer & Isabelle Guénal - 2024 - Bioessays 46 (2):2300125.
    DREAM complexes are transcriptional regulators that control the expression of hundreds to thousands of target genes involved in the cell cycle, quiescence, differentiation, and apoptosis. These complexes contain many subunits that can vary according to the considered target genes. Depending on their composition and the nature of the partners they recruit, DREAM complexes control gene expression through diverse mechanisms, including chromatin remodeling, transcription cofactor and factor recruitment at various genomic binding sites. This complexity is particularly high in mammals. Since the (...)
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  2.  6
    A conserved blueprint for the eye?Patrizia Lavia & Pidder Jansen-Dürr - 1999 - Bioessays 21 (10):843-850.
    In this review, we will focus on the role played by transcription factors of the E2F/DP family in controlling the expression of genes that carry out important cell‐cycle control functions, thereby ensuring ordered progression through the mammalian cell division cycle. The emerging picture is that cell‐cycle progression depends on the execution of a regulatory cascade of gene expression, driven by E2F/DP transcription factors, which are in turn regulated by the products of some of these genes. That E2F factors are (...)
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  3.  21
    Transcriptional regulation of the dihydrofolate reductase gene.Jill E. Slansky & Peggy J. Farnham - 1996 - Bioessays 18 (1):55-62.
    As cells approach S phase, many changes occur to create an environment conducive for DNA synthesis and commitment to cell division. The transcription rate of many genes encoding enzymes involved in DNA synthesis, including the dihydrofolate reductase (dhfr) gene, increases at the G1/S boundary of the cell cycle. Although a number of transcription factors interact to finely tune the levels of dhfr RNA produced, two families of transcription factors, Sp1 and E2F, play central roles in modulating dhfr levels. A region (...)
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  4.  10
    The pragmatist family romance.Family Romance - 2008 - In Cheryl Misak (ed.), The Oxford handbook of American philosophy. New York: Oxford University Press.
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  5.  5
    Immigration Law Exceptionalism and the Administrative Procedure Act.Jill E. Family - 2023 - Public Affairs Quarterly 37 (3):209-225.
    Immigration law is exceptional enough to deserve an administrative law focus of its own. The Administrative Procedure Act (APA) does not demand uniformity in adjudication. Therefore, it may be counterintuitive to argue that any one area of administrative adjudication is exceptional. Removal adjudication is indeed exceptional because it is an extremely dysfunctional system, it operates in a double void of fewer constitutional protections and without the protections of the APA, it relies on a vast network of civil detention, and it (...)
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  6. Just a Minute.Region Family Law Professionals - forthcoming - Ethos: Journal of the Society for Psychological Anthropology.
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  7. The Origin of the Family, Private Property and the State.Friedrich Engels - 2010 - Penguin Books.
    The Origin of the Family, Private Property and the State (1884), was a provocative and profoundly influential critique of the Victorian nuclear family. Engels argued that the traditional monogamous household was in fact a recent construct, closely bound up with capitalist societies. Under this patriarchal system, women were servants and, effectively, prostitutes. Only Communism would herald the dawn of communal living and a new sexual freedom and, in turn, the role of the state would become superfluous.
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  8.  22
    Cross-Domain Effects of Ethical Leadership on Employee Family and Life Satisfaction: the Moderating Role of Family-Supportive Supervisor Behaviors.Shuxia Zhang & Yidong Tu - 2018 - Journal of Business Ethics 152 (4):1085-1097.
    Drawing on the work–family enrichment theory, the present study investigates the cross-domain effects of ethical leadership on employees’ family and life satisfaction. Moreover, it focuses on the mediating role of work–family enrichment and the moderated mediation process of family-supportive supervisor behaviors underlying the relationship between ethical leadership and employees’ family and life satisfaction. Using a sample of 371 employees and their immediate supervisors in China, we found that WFE mediated the relationship between ethical leadership and (...)
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  9.  31
    Contributions of the Family Resemblance Approach to Nature of Science in Science Education.Sibel Erduran, Zoubeida R. Dagher & Christine V. McDonald - 2019 - Science & Education 28 (3-5):311-328.
    The emergence of the Family Resemblance Approach to nature of science has prompted a fresh wave of scholarship embracing this new approach in science education. The FRA provides an ambitious and practical vision for what NOS-enriched science content should aim for and promotes evidence-based practices in science education to support the enactment of such vision. The present article provides an overview of research and development efforts utilizing the FRA and reviews recent empirical studies including those conducted in preservice science (...)
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  10.  3
    The Work-Family Spillover Effects of Customer Mistreatment for Service Employees: The Moderating Roles of Psychological Detachment and Leader–Member Exchange.Ran Zhang, Yunqiao Wu & Karen Ferreira-Meyers - 2019 - Frontiers in Psychology 10.
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  11.  11
    The Chinese Classic of Family Reverence: A Philosophical Translation of the X Iaojing.Henry Rosemont - 2008 - University of Hawai'i Press. Edited by Roger T. Ames.
    Few if any philosophical schools have championed family values as persistently as the early Confucians, and a great deal can be learned by attending to what they had to say on the subject. In the Confucian tradition, human morality and the personal realization it inspires are grounded in the cultivation of family feeling. One may even go so far as to say that, for China, family reverence was a necessary condition for developing any of the other human (...)
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  12.  6
    Account episodes in family discourse: the making of morality in everyday interaction.Laur A. Sterponi - 2003 - Discourse Studies 5 (1):79-100.
    This article investigates account episodes in Italian family dinner conversations and illustrates how sequential patterns and participation are organized in terms of preferences indexical of moral ideology and moral order. Accounts have been mostly examined as speech acts abstracted from embedding sequential environment; this article shows that different design features of the priming move in account episodes retrospectively define different aspects of a situation as problematic and prospectively activate the relevance for distinctive remedial moves. On an ideological level, narrative (...)
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  13.  36
    Un-Coupling Family Law: The Legal Recognition and Protection of Adult Unions Outside of Conjugal Coupledom.Frederik Swennen - 2020 - Feminist Legal Studies 28 (1):39-60.
    This article sets out to research and resolve the conceptual lag between the family as defined and recognised in law and the multiplicity of queer constellations of ‘intimate citizenship’ in which families are actually done. The focus is on adult unions outside of conjugal coupledom. The family law practices, and awareness and expectations of adults in such unions were analysed through 21 interviews and the content analysis of 40 documents and were projected against the applicable legal mould. The (...)
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  14.  27
    Values, Spirituality and Religion: Family Business and the Roots of Sustainable Ethical Behavior.Joseph H. Astrachan, Claudia Binz Astrachan, Giovanna Campopiano & Massimo Baù - 2020 - Journal of Business Ethics 163 (4):637-645.
    The inclusion of morally binding values such as religious—or in a broader sense, spiritual—values fundamentally alter organizational decision-making and ethical behavior. Family firms, being a particularly value-driven type of organization, provide ample room for religious beliefs to affect family, business, and individual decisions. The influence that the owning family is able to exert on value formation and preservation in the family business makes religious family firms an incubator for value-driven and faith-led decision-making and behavior. They (...)
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  15. Genetic links, family ties, and social bonds: Rights and responsibilities in the face of genetic knowledge.Rosamond Rhodes - 1998 - Journal of Medicine and Philosophy 23 (1):10 – 30.
    Currently, some of the most significant moral issues involving genetic links relate to genetic knowledge. In this paper, instead of looking at the frequently addressed issues of responsibilities professionals or institutions have to individuals, I take up the question of what responsibilities individuals have to one another with respect to genetic knowledge. I address the questions of whether individuals have a moral right to pursue their own goals without contributing to society's knowledge of population genetics, without adding to their (...)'s knowledge of its genetic history, and without discovering genetic information about themselves and their offspring. These questions lead to an examination of the presumed right to genetic ignorance and an exploration of a variety of social bonds. Analyzing cases in light of these considerations leads to a surprising conclusion about a widely accepted precept of genetic counseling, to some ethical insights into typical problems, and to some further unanswered questions about personal responsibility in the face of genetic knowledge. (shrink)
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  16. The Family Romance of the French Revolution.Lynn Hunt - 1995 - Diderot Studies 26:298-299.
     
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  17. The state of nature, the family and the state.Simone Zurbuchen - 2022 - In Mark Somos & Anne Peters (eds.), The state of nature: histories of an idea. Boston: Brill Nijhoff.
     
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  18.  68
    XII—Universals and Family Resemblances.Renford Bambrough - 1961 - Proceedings of the Aristotelian Society 61 (1):207-222.
    Renford Bambrough; XII—Universals and Family Resemblances, Proceedings of the Aristotelian Society, Volume 61, Issue 1, 1 June 1961, Pages 207–222, https://doi.
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  19.  25
    Family Matters: Feminist Concepts in African Philosophy of Culture.Nkiru Uwechia Nzegwu - 2006 - State University of New York Press.
    Charts new trends in gender studies through a compelling analysis of Igbo society.
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  20.  33
    Assessment of Burden Among Family Caregivers of Schizophrenia: Psychometric Testing for Short-Form Zarit Burden Interviews.Yu Yu, Zi-wei Liu, Wei Zhou, Xiao-Chuan Chen, Xing-yu Zhang, Mi Hu & Shui-Yuan Xiao - 2018 - Frontiers in Psychology 9.
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  21.  50
    How do clinicians prepare family members for the role of surrogate decision-maker?V. Cunningham Thomas, P. Scheunemann Leslie, M. Arnold Robert & White Douglas - 2018 - Journal of Medical Ethics 44 (1):21-26.
    Purpose Although surrogate decision-making is prevalent in intensive care units and concerns with decision quality are well documented, little is known about how clinicians help family members understand the surrogate role. We investigated whether and how clinicians provide normative guidance to families regarding how to function as a surrogate. Subjects and methods We audiorecorded and transcribed 73 ICU family conferences in which clinicians anticipated discussing goals of care for incapacitated patients at high risk of death. We developed and (...)
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  22.  25
    How do clinicians prepare family members for the role of surrogate decision-maker?Thomas V. Cunningham, Leslie P. Scheunemann, Robert M. Arnold & Douglas White - 2017 - Journal of Medical Ethics Recent Issues 44 (1):21-26.
    Purpose Although surrogate decision-making is prevalent in intensive care units and concerns with decision quality are well documented, little is known about how clinicians help family members understand the surrogate role. We investigated whether and how clinicians provide normative guidance to families regarding how to function as a surrogate. Subjects and methods We audiorecorded and transcribed 73 ICU family conferences in which clinicians anticipated discussing goals of care for incapacitated patients at high risk of death. We developed and (...)
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  23.  50
    Downsizing and Stakeholder Orientation Among the Fortune 500: Does Family Ownership Matter?Eleni Stavrou, George Kassinis & Alexis Filotheou - 2007 - Journal of Business Ethics 72 (2):149-162.
    While downsizing has been widely studied, its connection to firm ownership status and the reasons behind it are missing from extant research. We explore the relationship between downsizing and family ownership status among Fortune 500 firms. We␣propose that family firms downsize less than non-family firms, irrespective of performance, because their relationship with employees is based on normative commitments rather than financial performance alone. We suggest that their actions are related to employee- and community-friendly policies. We find that (...)
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  24.  35
    Family Resemblances and Family Trees: Two Cognitive Metaphors.Carlo Ginzburg - 2004 - Critical Inquiry 30 (3):537.
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  25.  17
    Ethical Concerns of Patients and Family Members Arising During Illness or Medical Care.Marion Danis, Christine Grady, Mariam Noorulhuda, Ben Krohmal, Henry Silverman, Lee Schwab, Hae Lin Cho, Melissa Goldstein & Paul Wakim - 2023 - AJOB Empirical Bioethics 14 (4):218-226.
    Patients and family members (N = 671) were surveyed in five Mid-Atlantic U.S. hospitals to ascertain the number and kinds of ethical concerns they are presently experiencing or have previously experienced while being sick or receiving medical care. Seventy percent of participants had at least one (range 0–14) type of ethical concern or question. The most commonly experienced concerns pertained to being unsure how to plan ahead or complete an advance directive (29.4%), being unsure whether someone in the (...) was able to make their own decisions (29.2%), deciding about limiting life-sustaining treatments (28.6%), wondering about disclosing personal medical information to others in the family (26.4%) and not being sure whether to undergo treatment because of cost (26.2%). Most were interested to some degree in getting help from ethics consultants in the future (76.6%). Given this prevalence, common concerns might usefully be addressed systematically, rather than exclusively on a case-by-case basis. (shrink)
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  26.  25
    A Family of Neighborhood Contingency Logics.Jie Fan - 2019 - Notre Dame Journal of Formal Logic 60 (4):683-699.
    This article proposes the axiomatizations of contingency logics of various natural classes of neighborhood frames. In particular, by defining a suitable canonical neighborhood function, we give sound and complete axiomatizations of monotone contingency logic and regular contingency logic, thereby answering two open questions raised by Bakhtiari, van Ditmarsch, and Hansen. The canonical function is inspired by a function proposed by Kuhn in 1995. We show that Kuhn’s function is actually equal to a related function originally given by Humberstone.
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  27.  43
    The Family in Medical Decision Making: Japanese Perspectives.Michael D. Fetters - 1998 - Journal of Clinical Ethics 9 (2):132-146.
  28. A Confucian Worldview and Family-Based Informed Consent: A Case of Concealing Illness from the Patient in China.Wenqing Zhao - 2015 - In Ruiping Fan (ed.), Family-Oriented Informed Consent: East Asian and American Perspectives. Cham: Springer Verlag.
     
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  29.  26
    Family-Oriented Informed Consent: East Asian and American Perspectives.Ruiping Fan (ed.) - 2015 - Cham: Springer Verlag.
    In recent years, Confucian ethics has been considered as an alternative to the individual-oriented model of medical decision-making that is dominating in the modern West.
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  30.  17
    Ideology and the Patriarchal Family: Nerval and Flora Tristan.Phyllis Zuckerman - 1976 - Substance 5 (15):146.
  31.  7
    The Family Wage.Hilary Land - 1980 - Feminist Review 6 (1):55-77.
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  32.  10
    Embodied reminders in family interactions: Multimodal collaboration in remembering activities.Fátima Galiana Castelló & Lucas M. Bietti - 2013 - Discourse Studies 15 (6):665-686.
    The aim of our study is to show the ways in which family members coordinate their minds, bodies and language in a functional and goal-oriented manner when they are jointly remembering shared events that they had experienced together as a group. So far, little attention has been paid to the influence that the interplay of multiple behavioral channels have in collaborative remembering in small groups. Our goal is to specifically examine the central role that direct questions have when they (...)
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  33.  3
    The holy family.Karl Marx & Friedrich Engels - 1956 - Moscow,: Foreign Languages Pub. House. Edited by Karl Marx.
    A new 2023 translation into American English of Marx's influential 1845 "Die heilige Familie oder Kritik der kritischen Kritik" from the original manuscript. This edition includes a new introduction by the translator and reference materials including a Glossary of Philosophic and Economic Marxist Terminology, an Index of Personalities Associated with Marx and a Timeline of Marx’s Life and Works. This is Volume IV in The Complete Works of Karl Marx by NL Press. The Holy Family is Marx's first foray (...)
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  34.  30
    Revisiting the Effect of Family Involvement on Corporate Social Responsibility: A Behavioral Agency Perspective.Victor Cui, Shujun Ding, Mingzhi Liu & Zhenyu Wu - 2018 - Journal of Business Ethics 152 (1):291-309.
    This paper sheds light on the incongruent findings concerning the relationship between family involvement and firms’ corporate social responsibility. While prior studies have mainly taken the perspective of families’ socioemotional wealth preservation, we approach this relationship from the perspective of behavioral agency theory, highlighting the important role played by CEOs’ family memberships. Specifically, we posit that family firms are more likely to invest in CSR when their CEOs are members of the controlling families. Furthermore, we examine how (...)
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  35.  45
    Family Friendship in Aristotle’s Ethics.Elizabeth Belfiore - 2001 - Ancient Philosophy 21 (1):113-132.
  36.  16
    Family Loneliness: Its Effects in the Development of Empathy, Teamwork and Lifelong Learning Abilities in Medical Students.Nancy Berduzco-Torres, Pamela Medina, Begonia Choquenaira-Callañaupa, Montserrat San-Martín, Roberto C. Delgado Bolton & Luis Vivanco - 2020 - Frontiers in Psychology 11.
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  37.  37
    Revisiting W ittgenstein on Family Resemblance and Colour(s).Lin Ma & Jaap van Brakel - 2016 - Philosophical Investigations 39 (3):254-280.
    We argue that all general concepts are family resemblance concepts. These include concepts introduced by ostension, such as colour(s). Concepts of colour and of each of the specific colours are family resemblance concepts because similarities concerning an open‐ended range of colour or of appearance features crop up and disappear. After discussing the notion of “same colour” and Wittgenstein's use of the phrase “our colours”, we suggest family resemblance concepts in one tradition can often be extended to (...) resemblance concepts in another tradition, illustrated by Wittgenstein's use of the words Spiel and “game”. (shrink)
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  38.  10
    Family Environment Variables as Predictors of School Absenteeism Severity at Multiple Levels: Ensemble and Classification and Regression Tree Analysis.Mirae J. Fornander & Christopher A. Kearney - 2019 - Frontiers in Psychology 10.
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  39.  42
    Family tombs and tomb cult in ancient Athens: tradition or traditionalism?Sarah C. Humphreys - 1980 - Journal of Hellenic Studies 100:96-126.
    Fustel de Coulanges' thesis that ancient society was founded upon the cult of ancestral tombs has had, for a thoroughly self-contradictory argument, a remarkably successful career. Neither Fustel himself nor the many subsequent scholars who have quoted his views with approval faced clearly the difficulty of deriving a social structure dominated by corporate descent groups from the veneration of tombs placed in individually owned landed property. On the whole, historians have tended to play down Fustel's insistence on the relation between (...)
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  40.  13
    Effects of Family Demographics and Household Economics on Sidama Children’s Nutritional Status.Baili Gall, Hui Wang, Samuel J. Dira & Courtney Helfrecht - 2022 - Human Nature 33 (3):304-328.
    Weight- (WAZ), height- (HAZ), and BMI-for-age (BMIZ) are frequently used to assess malnutrition among children. These measures represent different categories of risk and are usually hypothesized to be affected by distinct factors, despite their inherent relatedness. Life history theory suggests weight should be sacrificed before height, indicating a demonstrable relationship among them. Here we evaluate impact of family composition and household economics on these measures of nutritional status and explore the role of WAZ as a factor in HAZ. Anthropometrics, (...)
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  41.  67
    Justice and the family.Francis Schrag - 1976 - Inquiry: An Interdisciplinary Journal of Philosophy 19 (1-4):193 – 208.
    Using Rawls's theory as illustration, I argue that any conception of justice which includes a commitment to equality of opportunity eventually must collide with a commitment to the family. I then contend that the link between justice and equality of opportunity cannot be severed by showing that one powerful attempt to do so founders. Borrowing from Martin Buber, I try to show that the perspective required by justice is different from and opposed to that required for intimate relations. Moreover, (...)
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  42.  29
    Orientation Toward Key Non-family Stakeholders and Economic Performance in Family Firms: The Role of Family Identification with the Firm.Mª de la Cruz Déniz-Déniz, Mª Katiuska Cabrera-Suárez & Josefa D. Martín-Santana - 2020 - Journal of Business Ethics 163 (2):329-345.
    Based on the literature on stakeholder management and family firm dynamics, this research analyses the relationship between three constructs: the identification of business families with their family firms, FFs’ orientation toward key non-family stakeholders, and the achievement of better economic performance. Data analyses from 374 family and non-family members of 173 Spanish FFs show that a high level of family identification with their firms affects the orientation of FFs toward key non-family stakeholders in (...)
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  43.  22
    The Study of the Relations among Ethical Considerations, Family Management and Organizational Performance in Corporate Governance.C. -F. Wu - 2006 - Journal of Business Ethics 68 (2):165-179.
    Corporate governance is increasingly becoming an issue of global concern, not least because we are more and more living in a corporate world that transcends international boundaries. The main purpose and motivation of this study is to determine how the international community should motivate businesses in fostering exemplary corporate governance, therefore eliminating obstacles to ethically exemplary behavior. The empirical approach utilized here has been applied to 161 businesses, both listed and over-the-counter (OTC) companies, with the results indicating that ethical considerations, (...)
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  44.  11
    Intentional Parenthood and the Nuclear Family.Liezl Zyl - 2002 - Journal of Medical Humanities 23 (2):107-118.
    Reproductive techniques and practices, ranging from ordinary birth-control measures and artificial insemination to embryo transfer and surrogate motherhood, have greatly enhanced our range of reproductive choices. As a consequence, they pose a number of difficult moral and legal questions with regard to the formation of a family and our conception of parenthood. A view that is becoming increasingly common is that parental rights and responsibilities should not be based on genetic relationships but should instead be seen as arising from (...)
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  45.  33
    Staff and family relationships in end-of-life nursing home care.Elisabeth Gjerberg, Reidun Førde & Arild Bjørndal - 2011 - Nursing Ethics 18 (1):42-53.
    This article examines the involvement of residents and their relatives in end-of-life decisions and care in Norwegian nursing homes. It also explores challenges in these staff—family relationships. The article is based on a nationwide survey examining Norwegian nursing homes’ end-of-life care at ward level. Only a minority of the participant Norwegian nursing home wards ‘usually’ explore residents’ preferences for care and treatment at the end of their life, and few have written procedures on the involvement of family caregivers (...)
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  46.  78
    Family-oriented Health Savings Accounts: Facing the Challenges of Health Care Allocation.R. Fan, X. Chen & Y. Cao - 2012 - Journal of Medicine and Philosophy 37 (6):507-512.
  47.  9
    The Right to Family Unification for Refugees.Eilidh Beaton - 2023 - Social Theory and Practice 49 (1):1-28.
    A handful of scholars have offered explanations for why states with otherwise restrictive immigration laws should relax their demands for people applying to immigrate for family reasons. However, much less has been said about the family unification rights of refugees. This paper extends the existing discussion on family-based immigration to refugees, arguing that: (1) states have stronger duties to reunite refugee families; (2) some refugees should be entitled to reunite with their “extended” family; (3) refugee (...) reunion should not be subject to financial conditions; and (4) the right to family reunion is especially strong for refugee children. (shrink)
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  48. The Experiences and Challenges Faced by COVID-19 Family Survivors: A Phenomenological Study of Mothers' Perspectives.Riabel Sy, Joy Almarie Aglamma, Arlan Deluna, Shainalhyn Gado, Luis Maranan, Alyssa Lara Termulo & Jhoselle Tus - 2022 - Psychology and Education: A Multidisciplinary Journal 12 (1):133-167.
    Due to the outbreak of COVID-19 many families experience the threat of the COVID-19. This study aims to explore the lived experiences, challenges, and coping mechanisms of COVID-19 Family Survivors. The study employed the Interpretative Phenomenological Analysis with ten (10) participants. Based on the findings, the following conclusions were drawn: (1) Most of the participants consulted health professionals for their medications and advised herbal medicines in boosting their immune system. (2) Family survivors had to make adaptations to their (...)
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  49.  9
    The family traditions of the gens Marcia between the fourth and third centuries B.c.Davide Morelli - 2021 - Classical Quarterly 71 (1):189-199.
    In the mid fourth century b.c. some Roman gentes drew on a Pythagorean tradition. In this tradition, Numa's role of Pythagoras’ disciple connected Rome with Greek elites and culture. The Marcii, between 304 and 300 b.c., used Numa's figure, recently reshaped by the Aemilii and the Pinarii for their propaganda, to promote the need for a plebeian pontificate. After the approval of the Ogulnium plebiscite, the needs for this kind of propaganda fell away. When Marcius Censorinus became censor, Numa's pontificate (...)
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  50.  59
    Revisiting Wittgenstein on Family Resemblance and Colour.Lin Ma & Jaap Brakel - 2016 - Philosophical Investigations 39 (2):254-280.
    We argue that all general concepts are family resemblance concepts. These include concepts introduced by ostension, such as colour. Concepts of colour and of each of the specific colours are family resemblance concepts because similarities concerning an open-ended range of colour or of appearance features crop up and disappear. After discussing the notion of “same colour” and Wittgenstein's use of the phrase “our colours”, we suggest family resemblance concepts in one tradition can often be extended to (...) resemblance concepts in another tradition, illustrated by Wittgenstein's use of the words Spiel and “game”. (shrink)
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