The KCTD family includes tetramerization (T1) domain containing proteins with diverse biological effects. We identified a novel member of the KCTD family, BTBD10. A comprehensive analysis of protein‐protein interactions (PPIs) allowed us to put forth a number of testable hypotheses concerning the biological functions for individual KCTD proteins. In particular, we predict that KCTD20 participates in the AKT‐mTOR‐p70 S6k signaling cascade, KCTD5 plays a role in cytokinesis in a NEK6 and ch‐TOG‐dependent manner, KCTD10 regulates the RhoA/RhoB pathway. Developmental regulator KCTD15 (...) represses AP‐2α and contributes to energy homeostasis by suppressing early adipogenesis. TNFAIP1‐like KCTD proteins may participate in post‐replication DNA repair through PCNA ubiquitination. KCTD12 may suppress the proliferation of gastrointestinal cells through interference with GABAb signaling. KCTD9 deserves experimental attention as the only eukaryotic protein with a DNA‐like pentapeptide repeat domain. The value of manual curation of PPIs and analysis of existing high‐throughput data should not be underestimated. (shrink)

This article correlates fine-grained semantic variability and change with measures of occurrence frequency to investigate whether a word’s degree of semantic change is sensitive to how often it is used. We show that this sensitivity can be detected within a short time span (i.e., 20 years), basing our analysis on a large corpus of German allowing for a high temporal resolution (i.e., per month). We measure semantic variability and change with the help of local semantic networks, combining elements of deep (...) learning methodology and graph theory. Our micro-scale analysis complements previous macro-scale studies from the field of natural language processing, corroborating the finding that high token frequency has a negative effect on the degree of semantic change in a lexical item. We relate this relationship to the role of exemplars for establishing form–function pairings between words and their habitual usage contexts. (shrink)

First published in 1994. Routledge is an imprint of Taylor & Francis, an informa company.

Abstractabstract There are estimated to be five million vegetarians in the United Kingdom and another four million in the United States. There are numerous vegetarians elsewhere in the world: around fifteen million, for instance, in India. Some of these vegetarians are parents. And some of the vegetarian parents will bring up their children to be vegetarian, too. Is this a permissible course of action? Or should vegetarian parents raise omnivorous offspring? In this article, I consider three arguments that aim to (...) show that a parent should not raise a child on a vegetarian diet. None of these arguments are convincing and I know of no better ones — so I conclude that it is permissible for a parent to raise her child as a vegetarian. (shrink)

What makes a measure of well-being valid? The dominant approach today, construct validation, uses psychometrics to ensure that questionnaires behave in accordance with background knowledge. Our first claim is interpretive—construct validation obeys a coherentist logic that seeks to balance diverse sources of evidence about the construct in question. Our second claim is critical—while in theory this logic is defensible, in practice it does not secure valid measures. We argue that the practice of construct validation in well-being research is theory avoidant, (...) favoring a narrow focus on statistical tests while largely ignoring relevant philosophical considerations. (shrink)

What sort of claims do scientific models make and how do these claims then underwrite empirical successes such as explanations and reliable policy interventions? In this paper I propose answers to these questions for the class of models used throughout the social and biological sciences, namely idealized deductive ones with a causal interpretation. I argue that the two main existing accounts misrepresent how these models are actually used, and propose a new account. *Received July 2006; revised August 2008. †To contact (...) the author, please write to: Department of Philosophy, University of Missouri, St. Louis, 599 Lucas Hall (MC 73), One University Blvd., St. Louis, MO 63121-4400; e-mail: [email protected]. (shrink)

In his influential paper, ‘General Criteria and Reasons in Aesthetics’, Frank Sibley outlines what is taken to be a generalist view (shared with Beardsley) such that there are general reasons for aesthetic judgement, and his account of the behaviour of such reasons, which differs from Beardsley's. In this paper my aim is to illuminate Sibley's position by employing a distinction that has arisen in meta-ethics in response to recent work by Jonathan Dancy in particular. Contemporary research involves two related yet (...) distinct debates: (i) that between the particularist and the generalist on the status of moral principles; and (ii) that between holists and atomists on the nature of reasons. This division of labour has no correlate within the aesthetic particularism–generalism debate, and I will show how the ideas developed in relation to meta-ethics illuminate a difficulty with Sibley's view. I argue that we should understand Sibley as subscribing to both particularism and a version of holism about aesthetic reasons. (shrink)

The article examines the theory of knowledge of the Russian philosopher of the XXth century V. E. Sesemann and his understanding of reality. The author emphasizes that in the field of epistemology, Sesemann, being influenced by E. Husserlʼs phenomenology, first of all, answers the question of the possibility of cognition of the reality of the surrounding world and the special role of perception in this process. However, unlike Husserl, Sesemann is convinced that true knowledge is achievable not only in relation (...) to the things of the world, but also in relation to their relationships and interrelations, which are seen in a special kind of intuition – a conceptual intuition. Seseman believes that the cognition of the surrounding world depends not only on the cognizing subject, but also on the objectivity itself, which may not always be accessible to cognition. The article pays close attention to Sesemannʼs understanding of reality as the reality of becoming, one of the types of which is movement. In this case, Sesemann argues, it is impossible to create a unified picture of the world, and our knowledge can only be probabilistic. The author examines the epistemological and ontological views of Seseman in the context of his time, comparing them with the main trends of philosophy of the XXth century, primarily with phenomenology and neo-Kantianism. (shrink)

In Valuing Health, Dan Hausman argues that well-being is not measurable, at least not in the way that science and policy would require. His argument depends on a demanding conception of well-being and on a pessimistic verdict upon the existing measures of subjective well-being. Neither of these reasons, I argue, warrant as much skepticism as Hausman professes.

This paper develops an inference system for natural language within the ‘Natural Logic’ paradigm as advocated by van Benthem, Sánchez and others. The system that we propose is based on the Lambek calculus and works directly on the Curry-Howard counterparts for syntactic representations of natural language, with no intermediate translation to logical formulae. The Lambek -based system we propose extends the system by Fyodorov et~al., which is based on the Ajdukiewicz/Bar-Hillel calculus Bar Hillel,. This enables the system to deal with (...) new kinds of inferences, involving relative clauses, non-constituent coordination, and meaning postulates that involve complex expressions. Basing the system on the Lambek calculus leads to problems with non-normalized proof terms, which are treated by using normalization axioms. (shrink)

The burgeoning science of well-being makes no secret of being value laden: improvement of well-being is its explicit goal. But in order to achieve this goal its concepts and claims need to be value adequate; that is, they need, among other things, to adequately capture well-being. In this article I consider two ways of securing this adequacy—first, by relying on philosophical theory of prudential value and, second, by the psychometric approach. I argue that neither is fully adequate and explore an (...) alternative. This alternative requires thorough changes in the way philosophers theorize about well-being. (shrink)

Julian Reiss correctly identified a trilemma about economic models: we cannot maintain that they are false, but nevertheless explain and that only true accounts explain. In this reply we give reasons to reject the second premise ? that economic models explain. Intuitions to the contrary should be distrusted.

As Justin Biddle and I have argued, climate skepticism can be epistemically problematic when it displays a systematic intolerance of producer risks at the expense of public risks : 261–278, 2015). In this paper, I will provide currently available empirical evidence that supports our account, and I discuss the normative consequences of climate skepticism by drawing upon Philip Kitcher’s “Millian argument against the freedom of inquiry.” Finally, I argue that even though concerns regarding inappropriate disqualification of dissent are reasonable, a (...) form of “targeting” dissent—namely revealing manufactured dissent—is required in order to identify epistemically detrimental dissent and, thus, to protect scientific and public discourse. (shrink)

Citizen-gathered evidence (CGE) gathered by individuals organized in collectives have the potential to demonstrate environmental and social wrongdoings in court. We identify (collective) agency and resistance in how individuals and communities that have been exposed to socio-environmental stressors turn to gather CGE. We explore the modes through which people gather scientific data, produce CGE, alert authorities to environmental harm, and the methods by which data can be shared with communities, beginning with the case studies of civic environmental monitoring addressing coal (...) ash pollution in North Carolina. We analyze the case studies through a theoretical lens built on (1) the theory of civic monitoring “as resistance;” (2) the argument that CGE can embody “collective intelligence;” and (3) the concept of “crowd science” through a decentralized yet coordinated network. In the first part of the article, we introduce the case studies. Then, we illustrate our theoretical frame as applied to the analysis of the cases. We discuss the cases and in particular the CGE at issue through the prism of the frame. We demonstrate how CGE can be valuable not only for civil society and civic organizations, but also for competent authorities. In our conclusion, we identify critical junctures of our case studies, such as that of “knowledge crowdsourcing” to demand justice that triggers the government to take action and the existence of a “coordinated” yet decentralized crowd to capture the full extension of the problem. Lastly, we outline the limitations of our study, a future research agenda, and still open questions. (shrink)

First-person reports are central to the study of subjective well-being in contemporary psychology, but there is much disagreement about exactly what sort of first-person reports should be used. This paper examines an influential proposal to replace all first-person reports of life satisfaction with introspective reports of affect. I argue against the reasoning behind this proposal, and propose instead a new strategy for deciding what measure is appropriate.

Can social phenomena be understood by analyzing their parts? Contemporary economic theory often assumes that they can. The methodology of constructing models which trace the behavior of perfectly rational agents in idealized environments rests on the premise that such models, while restricted, help us isolate tendencies, that is, the stable separate effects of economic causes that can be used to explain and predict economic phenomena. In this paper, I question both the claim that models in economics supply claims about tendencies (...) and also the view that economics, when successful, necessarily follows this method. When economics licenses successful policy interventions, as it did in the case of the Federal Communications Commission spectrum auctions, its method is not to study tendencies but rather to study the phenomenon as a whole. Key Words: economic models • tendencies • economic experiments • policy making • John Stuart Mill. (shrink)

Background: In modern healthcare, the role of solidarity, altruism and the natural response to moral challenges in life-threatening situations is still rather unexplored. The COVID-19 pandemic provided an opportunity to obtain a deeper understanding of nurses’ willingness to care for patients during crisis. Objective: To elucidate clinical expressions of ontological situational ethics through nurses’ willingness to work during a pandemic. Research design, participants and context: A qualitative study with an interpretive design was applied. Twenty nurses who worked in intensive care (...) unit at two Swedish hospitals during the first, second, and third waves of the COVID-19 pandemic were interviewed. The analysis was interpretative and applied a theoretical ethics perspective. Ethical considerations: The study was approved by the Swedish Ethical Review Authority and informed consent was obtained from all participants. Findings: From a philosophical perspective, the nurses expressed sovereign life expressions of mercy and compassion, which arose spontaneously in response to seeing vulnerable fellow humans. They referenced ‘‘the nurse inside me’’ and their choice of profession as motives to provide care. Ontological situational ethics in culture and norms were noted in the constructs of competence, responsibility, solidarity with colleagues and organization; and interest and learning were driving forces. Ethical demand was evident when nurses expressed ideas of meaningfulness in helping their fellow humans; but themes of ambiguity, exhaustion and unwillingness were also present. Conclusions: The nurses showed a high willingness to care for patients during a crisis. Responding to the ethical demand and to care for vulnerable human beings while risking their own health and lives could be interpreted as an inter-human vocation. These spontaneous altruistic actions saved the lives of many patients during the pandemic and need to be understood and supported. (shrink)

This article discusses two normative questions raised by cases of colonial settlement. First, is it sometimes wrong to migrate and settle in a previously inhabited land? If so, under what conditions? Second, should settler countries ever take steps to undo wrongful settlement, by enforcing repatriation and return? The article argues that it is wrong to settle in another country in cases where one comes with intent to colonize the population against their will, or one possesses an adequate territorial base somewhere (...) else, lacks an urgent interest in moving, and seeks to settle in a new place under conditions where settlement would severely harm the practices of prior occupants. It also argues for a presumption of repatriation and return in the first generation of wrongful settlement and holds that these remedies may be extended to second and higher generations in some – but not all – cases. (shrink)

This article is a mutual introduction of the science of well-being to philosophy of science and an explanation of how the two disciplines can benefit each other. In the process, I argue that the science of well-being is not helpfully viewed as a social or a natural, but rather as a mixed, science. Hence, its methodology will have to attend to its specific features. I discuss two of its methodological problems: justifying the role of values, and validating measures. I suggest (...) that tackling them calls for developing mid-level rather than high theories of well-being. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:1 & 2 Thessalonians by Douglas FarrowAnna Silvas1 & 2 Thessalonians by Douglas Farrow (Grand Rapids, MI: Brazos, 2020), xx + 336 pp.1 and 2 Thessalonians are probably the very first written testimonies of early Christianity. When Paul wrote 1 Thessalonians in AD 50, Our Lord Jesus Christ had "accomplished his exodus in Jerusalem" (see Luke 9:31) not twenty years before. Here we find the paradosis of the (...) Mystery of Christ among the Gentiles, the first articulations of Trinitarian faith (see 1 Thess 1:2-5), expressions of longing for the coming Parousia of Christ, warnings of a strange lawlessness already at work ripening towards a great apostasy and the coming of the "man of lawlessness."Douglas Farrow has pondered 1 and 2 Thessalonians for many years, attested by his numerous expositions and essays over three decades. He brings to his task a ready command of Greek, Hebrew, and Latin, and a vast reading of historical commentary and controversy, an intense personal and ecclesial faith, and a sense of historical, prophetic, and pastoral urgency.Throughout the book are excurses on themes opened up by the words and phrases of St Paul's text: Satan (82-86); the sexual body and virtue in sex, divorce, and remarriage (95-114); the remedial pains of purgatory (beginning in this life); the reality of final retribution, the finality of hell; the untenability of so-called "universalism" (131-41,178-84,192-96); the imminency and the delay of the Parousia (199-204); the apostasy / man of lawlessness / Antichrist; the temple in which the Antichrist seats himself (205-42); the mystery of lawlessness at work, especially in undermining the Church (245-61).In studying Paul's eschatological themes, Farrow necessarily ponders other scriptural texts leading in the same direction: Dani 7-12; Jesus's Olivet Discourse in its most extensive form at Matt 24:1-25:46 (though it really begins at 23:23); 2 Pet 2:1-5, 3:3-15; much of the Rev 6:1 through 19:21; [End Page 398] Deut 32:1-43 (Farrow says the Song of Moses encapsulates the whole of human history); Psalms 97 (LXX 96); 110 (LXX 109); Wis 4-5, 10-19; Sirach 50; Joel; Zech 8-14; Mai 3-4; 2 Mace 5-9; Isa 66:5,14-16; and so on. Farrow holds that Paul worked from knowledge of Jesus's apocalyptic teachings in aversion closest to Matthew's (138,142,184, 189, 205).Farrow takes companions in his exegesis: Irenaeus, Hippolytus, Cyril of Jerusalem, John Chrysostom, Augustine, Haimo, Anselm, Aquinas, and others. He knows Luther's hermeneutics and Calvinist disputes about supra- and infra-sessionism and double predestinationism. He consults more recent prophets, quoting at length from Newman's amazingly prescient 1838 discourses on the last times, Solovyovin 1899, and Fulton Sheen in 1948 and 1958. Another exegete is an artist: Luca Signorelli, whose Disputation of the Antichrist in Orvieto Cathedral Farrow refers to several times.Farrow shows his affinity with Irenaeus. That means cleaving to the visible and invisible truths of the Incarnation of God the Word, respecting concrete and embodied realities, keeping in view the transcendent goal ("The glory of God is a living man—and the life of man is in the vision of God"), instinctively flinching at gnosticizing tendencies—sophisticated re-interpretations of Scripture that elide the rule of faith and dissolve truth. It means a ruling sense of the Kingdom of God as an intervention from heaven rather than generating from man or from the earth. It means a spirit of obedience to the commandments, to the paradosis that descends to us from above in Christ, effected by the Spirit in the ecclesia, the company of brethren destined to "gather to Christ" at his coming (1 Thess 2:1), who practice that final gathering to Christ by participating in the Eucharist on the "Eighth Day," the Lord's Day.Farrow deplores the patchy reading of 1 and 2 Thessalonians in the lectionaries: "While 1 Thessalonians fares a little better, barely half of 2 Thessalonians is read in the Churches" (11). Missing is the eschatologically pivotal 2 Thess 2:3-15, where Paul, distinguishing... (shrink)

_Levinas, Subjectivity, Education_ explores how the philosophical writings of Emmanuel Levinas lead us to reassess education and reveals the possibilities of a radical new understanding of ethical and political responsibility. Presents an original theoretical interpretation of Emmanuel Levinas that outlines the political significance of his work for contemporary debates on education Offers a clear analysis of Levinas’s central philosophical concepts, including the place of religion in his work, demonstrating their relevance for educational theorists Examines Alain Badiou’s critique of Levinas’s work (...) Considers the practical implications of Levinas’ theories for concrete educational practices and frameworks. (shrink)

How can we explain the structure of perceptual experience? What is it that we perceive? How is it that we perceive objects and not disjoint arrays of properties? By which sense or senses do we perceive objects? This book investigates Aristotle's views on these and related questions.

Background: Ethics and dignity in prehospital emergency care are important due to vulnerability and suffering. Patients can lose control of their body and encounter unfamiliar faces in an emergency situation. Objective: To describe what specialist ambulance nurse students experienced as preserved and humiliated dignity in prehospital emergency care. Research design: The study had a qualitative approach. Method: Data were collected by Flanagan’s critical incident technique. The participants were 26 specialist ambulance nurse students who described two critical incidents of preserved and (...) humiliated dignity, from prehospital emergency care. Data consist of 52 critical incidents and were analyzed with interpretive content analysis. Ethical considerations: The study followed the ethical principles in accordance with the Declaration of Helsinki. Findings: The result showed how human dignity in prehospital emergency care can be preserved by the ambulance nurse being there for the patient. The ambulance nurses meet the patient in the patient’s world and make professional decisions. The ambulance nurse respects the patient’s will and protects the patient’s body from the gaze of others. Humiliated dignity was described through the ambulance nurse abandoning the patient and by healthcare professionals failing, disrespecting, and ignoring the patient. Discussion: It is a unique situation when a nurse meets a patient face to face in a critical life or death moment. The discussion describes courage and the ethical vision to see another human. Conclusion: Dignity was preserved when the ambulance nurse showed respect and protected the patient in prehospital emergency care. The ambulance nurse students’ ethical obligation results in the courage to see when a patient’s dignity is in jeopardy of being humiliated. Humiliated dignity occurs when patients are ignored and left unprotected. This ethical dilemma affects the ambulance nurse students badly due to the fact that the morals and attitudes of ambulance nurses are reflected in their actions toward the patient. (shrink)

On a common characterization, moral luck occurs when factors beyond agents’ control affect their moral responsibility. The existence of moral luck is widely contested, however. In this paper, I present a new challenge for deniers of moral luck. It seems that some factors beyond agents’ control—such as moral principles about blame- and praiseworthiness—clearly affect moral responsibility. Thus, moral luck deniers face a dialectical burden that has so far gone unnoticed. They must either point to a relevant difference between factors like (...) moral principles and the kind of factors that according to them do not affect moral responsibility or show how they can avoid having to point to such a difference. I argue that no obvious way to meet the challenge presents itself and that it thus amounts to a serious worry for deniers of moral luck. (shrink)

Ever since F. H. Bradley first formulated his famous regress argument philosophers have been hard at work trying to refute it. The argument fails, it has been suggested, either because its conclusion just does not follow from its premises, or it fails because one or more of its premises should be given up. In this paper, the Bradleyan argument, as well as some of the many and varied reactions it has received, is scrutinized.

Background Transcranial direct current stimulation (tDCS) is a brain stimulation technique currently being researched as an alternative or complimentary treatment for various neurological disorders. There is little knowledge about experiences of the participants of tDCS clinical research, especially from pediatric studies. Methods An interview study with typically developing minors (n = 19, mean age 13,66 years) participating in a tDCS study, and their parents (n = 18) was conducted to explore their views and experiences and inform the ethical analysis. Results (...) Children (10–13 years old) and adolescents (14–18 years old) reported good experiences with the stimulation. Next to financial incentives, main motives to participate in the study were curiosity and the possibility to help develop treatments for children affected by neurological disorders. They could also see a potential of using tDCS in a non-medical setting, especially regarding the provision of equal opportunity, e.g. in education. Parents also presented a positive attitude towards tDCS and their children participation in the basic research study. Nevertheless, their understanding of tDCS was rather poor. Even though many of them understood the techniques, they often did not see the link between the (current) lack of side effects and an absence of longitudinal studies. Parents were also cautious about using tDCS for non-medical/enhancement purposes. Conclusions The study findings show a need for more transparent information about the state of the art of tDCS, its function and what it might be able to offer, especially considering the good acceptability of tDCS. (shrink)

Action and Appearance is a collection of essays that look into the crucial and complex link between action and appearance in Hannah Arendt's political thought.Contributed by respected scholars, the essays articulate around the following themes: the emergence of political action when questioning the nature of law, subjectivity and individuality; the relationship between ethics and politics; the nexus of appearance, thinking and truth; and Arendt's writing as action and appearance. For Arendt, action is a worldly, public phenomenon that requires the presence (...) of others to have any effect. Therefore, to act is more than to decide as it is also to appear. Much has been said about Arendt's theory of action, but little attention has been paid to her approach to appearance as is done in this volume.Action and Appearance explores both Arendt's familiar texts and previously unpublished or recently rediscovered texts to challenge the established readings of her work. Adding to established debates, it will be a unique resource to anyone interested in Hannah Arendt, political thought, political theory, and political philosophy. (shrink)

SummaryIan Hunter's normative commitment is to civil philosophy. His sustained critique of metaphysical philosophy is to be understood in the context of his proposition that civil and moral philosophy are at war. Since civil philosophy is the only guarantor of social peace, the stakes are high.

The French Convention on Bioethics (États généraux de la bioéthique, 2009) were a perfect spot to observe new methods of organizing the participants of public debates into a hierarchy. Indeed, a privileged place was given to the citizen, and quite often the expert and the politician were devoid of their usual roles. This article will focus on the analysis of the very role given to the expert and to the expertise, both in the definition of the general framework of the (...) series of meetings and in public debates that took place in (among others) Marseille and Paris. This analysis makes obvious the idea that the major result of those Conventions does not consist in putting forward some original thoughts on biomedicine and its problems, but rather in promoting a new model of governance. In consequence, and if I am right, this promotion is being made precisely by diminishing the role of the expert (the intellectual). (shrink)

Стаття присвячена історії становлення жіночого рабинату в іудаїзмі США. Оскільки сміха (звання рабина) надається в теологічних навчальних закладах, то авторка акцентує свою увагу саме на них. Розглянуто позицію представників ортодоксального іудаїзму, які, базуючись на Галасі, забороняють жінкам ставати рабинами. Далі розглядається, яким чином навчальні заклади різних напрямів сучасного іудаїзму (реформістського, реконструктивістського та консервативного) приймали рішення про дозвіл жінкам вступати до рабинських факультетів та отримувати сміху. Авторка пов'язує ці зміни з феміністським рухом 1960-70 рр. Виділено загальні проблеми жінок під час навчання (...) та після його закінчення: жінки мають менше шансів стати рабинами в громадах, аніж чоловіки; жінкам важче знайти баланс між обов'язками рабина та їхніми жіночими функціями в сім'ї. Показано, що жінки привносять до рабинату нові цінності та стилі управління громадою ("спів-рабинат"). Вони також створюють релігійні обряди, присвячені суто жіночим життєвим циклам. (shrink)

The present reflection draws upon a tradition of energetic, world-facing critical legal scholarship to interrogate the anthropos assumed by the terminology of ‘anthropocentrism’ and of the ‘Anthropocene’. The article concludes that any ethically responsible future engagement with ‘anthropocentrism’ and/or with the ‘Anthropocene’ must explicitly engage with the oppressive hierarchical structure of the anthropos itself—and should directly address its apotheosis in the corporate juridical subject that dominates the entire globalised order of the Anthropocene age.

Computational explanations focus on information processing required in specific cognitive capacities, such as perception, reasoning or decision-making. These explanations specify the nature of the information processing task, what information needs to be represented, and why it should be operated on in a particular manner. In this article, the focus is on three questions concerning the nature of computational explanations: What type of explanations they are, in what sense computational explanations are explanatory and to what extent they involve a special, “independent” (...) or “autonomous” level of explanation. In this paper, we defend the view computational explanations are genuine explanations, which track non-causal/formal dependencies. Specifically, we argue that they do not provide mere sketches for explanation, in contrast to what for example Piccinini and Craver :283–311, 2011) suggest. This view of computational explanations implies some degree of “autonomy” for the computational level. However, as we will demonstrate that does not make this view “computationally chauvinistic” in a way that Piccinini or Kaplan :339–373, 2011) have charged it to be. (shrink)

This study examines the presence of ethical climates in skilled nursing facilities and identifies their antecedents (work group, job position, tenure). A cross-sectional survey design was implemented. A total of 359 facilities were selected in the Midwestern United States. Responses were received from nurses representing 100 of those facilities (28%). A total of 656 usable questionnaires were returned of the 3060 distributed (21.4% response rate). Descriptive statistics, confirmatory factor analysis, and multivariate and univariate analyses of variance were used. The results (...) confirmed the presence of five ethical climates. Significant differences between registered and licensed practical nurses with regard to egoistic and independence ethical climates were found. Furthermore, nurses in management and non-management positions differed significantly in their perceptions of caring and egoistic climates. The results suggest incongruence in value perceptions and imply that researchers and practitioners have to direct efforts towards preventing and identifying reasons behind this. (shrink)