This paper is concerned with the formulation and analysis of an epidemic model of COVID-19 governed by an eight-dimensional system of ordinary differential equations, by taking into account the first dose and the second dose of vaccinated individuals in the population. The developed model is analyzed and the threshold quantity known as the control reproduction number R0\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\mathcal {R}_{0}$$\end{document} is obtained. We investigate the equilibrium stability of the system, and the COVID-free equilibrium (...) is said to be locally asymptotically stable when the control reproduction number is less than unity, and unstable otherwise. Using the least-squares method, the model is calibrated based on the cumulative number of COVID-19 reported cases and available information about the mass vaccine administration in Malaysia between the 24th of February 2021 and February 2022. Following the model fitting and estimation of the parameter values, a global sensitivity analysis was performed by using the Partial Rank Correlation Coefficient (PRCC) to determine the most influential parameters on the threshold quantities. The result shows that the effective transmission rate (α)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$(\alpha )$$\end{document}, the rate of first vaccine dose (ϕ)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$(\phi )$$\end{document}, the second dose vaccination rate (σ)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$(\sigma )$$\end{document} and the recovery rate due to the second dose of vaccination (η)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$(\eta )$$\end{document} are the most influential of all the model parameters. We further investigate the impact of these parameters by performing a numerical simulation on the developed COVID-19 model. The result of the study shows that adhering to the preventive measures has a huge impact on reducing the spread of the disease in the population. Particularly, an increase in both the first and second dose vaccination rates reduces the number of infected individuals, thus reducing the disease burden in the population. (shrink)

An important method for finding the optimal solution for linear and nonlinear models is the graphical method, which is used if the linear or nonlinear mathematical model contains one, two, or three variables. The models that contain only two variables are among the most models for which the optimal solution has been obtained graphically, whether these models are linear or non-linear in references and research that are concerned with the science of operations research, when the data of the issue (...) under study is classical data. In this research, we will present a study through, which we present the graphical method for solving Neutrosophical nonlinear models in the following case: A nonlinear programming issue, the objective function is a nonlinear function, and the constraints are linear functions. Note that we can use the same method if (i) the objective function follower is a linear follower and the constraints are nonlinear; (ii) the objective function is a non-linear follower and the constraints are non-linear. In the three cases, the nonlinear models are neutrosophic, and as we know, the mathematical model is a nonlinear model if any of the components of the objective function or the constraints are nonlinear expressions, and the nonlinear expressions may be in both. At the left end of the constraints are neutrosophic values, at least one or all of them. Then, the possible solutions to the neutrosophic nonlinear programming problem are the set of rays that fulfills all the constraints. As for the region of possible solutions, it is the region that contains all the rays that fulfill the constraints. The optimal solution is the beam that fulfills all constraints and at which the function reaches a maximum or minimum value, depending on the nature of the issue under study (noting that it is not necessary to be alone). (shrink)

In this paper, I discuss the discovery of the DNA structure by Francis Crick and James Watson, which has provoked a large historical literature but has yet not found entry into philosophical debates. I want to redress this imbalance. In contrast to the available historical literature, a strong emphasis will be placed upon analysing the roles played by theory, model, and evidence and the relationship between them. In particular, I am going to discuss not only Crick and Watson's well-known model (...) and Franklin's x-ray diffraction pictures (the evidence) but also the less well known theory of helical diffraction, which was absolutely crucial to Crick and Watson's discovery. The insights into this groundbreaking historical episode will have consequences for the ‘new’ received view of scientific models and their function and relationship to theory and world. The received view, dominated by works by Cartwright and Morgan and Morrison ([1999]), rather than trying to put forth a ‘theory of models’, is interested in questions to do with (i) the function of models in scientific practice and (ii) the construction of models. In regard to (i), the received view locates the model (as an idealized, simplified version of the real system under investigation) between theory and the world and sees the model as allowing the application of the former to the latter. As to (ii) Cartwright has argued for a phenomenologically driven view and Morgan and Morrison ([1999]) for the ‘autonomy’ of models in the construction process: models are determined neither by theory nor by the world. The present case study of the discovery of the DNA structure strongly challenges both (i) and (ii). In contrast to claim (i) of the received view, it was not Crick and Watson's model but rather the helical diffraction theory which served a mediating purpose between the model and the x-ray diffraction pictures. In particular, Cartwright's take on (ii) is refuted by a comparison of Franklin's bottom-up approach with Crick and Watson's top-down approach in constructing the model. The former led to difficulties, which only a strong confidence in the structure incorporated in the model could circumvent. How to Get to the Structure 1.1 X-ray diffraction and its synthesis 1.2 Model building and Pauling's panache 1.3 The structure of proteins 1.3.1 A failed inference to the best explanation 1.3.2 The misleading 5.1 Å spot in proteins and how to get rid of it 1.3.3 Derived predictions from Pauling's alpha-helix of protein molecules The CCV Theory of Helical X-Ray Diffraction 2.1 The role of the CCV theory in the discovery of the DNA structure Killing the Helix 3.1 Appreciating all evidence—in vain Conclusion Epilogue: Chargaff's Ratios CiteULike Connotea Del.icio.us What's this? (shrink)

We show that the quantifier elimination result for the Shelah-Spencer almost sure theories of sparse random graphs $$G(n,n^{-\alpha })$$ given by Laskowski (Isr J Math 161:157–186, 2007) extends to their various analogues. The analogues will be obtained as theories of generic structures of certain classes of finite structures with a notion of strong substructure induced by rank functions and we will call the generics Baldwin–Shi hypergraphs. In the process we give a method of constructing extensions whose ‘relative rank’ is (...) negative but arbitrarily small in context. We give a necessary and sufficient condition for the theory of a Baldwin–Shi hypergraph to have atomic models. We further show that for certain well behaved classes of theories of Baldwin–Shi hypergraphs, the existentially closed models and the atomic models correspond. (shrink)

The present authors have given a mathematical model of Mach's principle and of the Mach–Einstein doctrine about the complete induction of the inertial masses by the gravitation of the universe. The analytical formulation of the Mach–Einstein doctrine is based on Riemann's generalization of the Lagrangian analytical mechanics (with a generalization of the Galilean transformation) on Mach's definition of the inertial mass and on Einstein's principle of equivalence. All local and cosmological effects—which are postulated as consequences of Mach's principle by (...) C. Neumann, Mach, Friedländer and Einstein—result from the Riemannian dynamics with the Mach–Einstein doctrine. In celestial mechanics it follows, in addition, Einstein's formula for the perihelion motion. In cosmology, the Riemannian mechanics yields two models of an evolutionary universe with the expansion lows R ~ t or R ~ t2. In this paper, secular consequences of the Mach–Einstein doctrine are examined concerning palaeogeophysics and celestial mechanics. The research predicted secular decrease of the Earth's flattening and secular acceleration of the motion of the Moon and of the planets. The numerical values of this secular effect agree very well with the empirical facts. In all cases, the secular variation $\dot{\alpha}$ of the parameter α is the order of magnitude $\dot{\alpha}=-H_0 \alpha$ , where H0 is the instantaneous value of the Hubble constant: $H_0 =\left({\dot{R}/R} \right)_0 \approx \left( {0.5-1.0} \right) \times 10^{-10}a^{-1}$ . The relation of the secular consequences of the Mach–Einstein doctrine to those of Dirac's hypothesis on the expanding Earth, and to Darwin's theory of tidal friction are also discussed. (shrink)

I argue that the contrast between models and theories is important for public policy issues. I focus especially on the way a mathematical model explains just one aspect of the data.

Mathematical models of biological patterns are central to contemporary biology. This paper aims to consider what these models contribute to biology through the detailed consideration of an important case: Hamilton’s selfish herd. While highly abstract and idealized, Hamilton’s models have generated an extensive amount of research and have arguably led to an accurate understanding of an important factor in the evolution of gregarious behaviors like herding and flocking. I propose an account of what these models are able to achieve (...) and how they can support a successful scientific research program. I argue that the way these models are interpreted is central to the success of such programs. (shrink)

Mathematical models provide explanations of limited power of specific aspects of phenomena. One way of articulating their limits here, without denying their essential powers, is in terms of contrastive explanation.

This chapter contains section titled: Some Personal Prefatory Remarks Introduction: Wittgenstein's Chief Contribution? The Reception of Wittgenstein's Philosophy of Mathematics in His Own Lifetime The Post 1956 Reaction.

Introduction 1. Perspectives on Wittgenstein: An Intermittently Opinionated Survey: Hans-Johann Glock. 2. Wittgenstein's Method: Ridding People of Philosophical Prejudices: Katherine Morris. 3. Gordon Baker's Late Interpretation of Wittgenstein: P. M. S. Hacker. 4. The Interpretation of the Philosophical Investigations: Style, Therapy, Nachlass: Alois Pichler. 5. Ways of Reading Wittgenstein: Observations on Certain Uses of the Word 'Metaphysics': Joachim Schulte. 6. Metaphysical/Everyday Use: A Note on a Late Paper by Gordon Baker: Hilary Putnam. 7. Wittgenstein and Transcendental Idealism: A. W. Moore. (...) 8. Simples and the Idea of Analysis in the Tractatus: Marie McGinn. 9. Words, Waxing and Waning: Ethics in/and/of the Tractatus Logico-Philosophicus: Stephen Mulhall. 10. The Uses of Wittgenstein's Beetle: Philosophical Investigations §293 and Its Interpreters: David G. Stern. 11. Bourgeois, Bolshevist or Anarchist?: The Reception of Wittgenstein's Philosophy of Mathematics: Ray Monk. 12. Wittgenstein and Ethical Naturalism: Alice Crary. (shrink)

It is one of the central aims of the philosophy of science to elucidate the meanings of scientific terms and also to think critically about their application. The focus of this essay is the scientific term predict and whether there is credible evidence that animal models, especially in toxicology and pathophysiology, can be used to predict human outcomes. Whether animals can be used to predict human response to drugs and other chemicals is apparently a contentious issue. However, when one empirically (...) analyzes animal models using scientific tools they fall far short of being able to predict human responses. This is not surprising considering what we have learned from fields such evolutionary and developmental biology, gene regulation and expression, epigenetics, complexity theory, and comparative genomics. (shrink)

One establishes oneself within science from the start. One does not reconstitute it from scratch. One does not found it. Alain Badiou, Le Concept de modèle1 [T]here are no crises within science, nor can there be, for science is the pure affirmation of difference. Alain Badiou, "Marque et manque" 2.

(2001). Family Physicians and the Family Covenant Model's Usefulness in Solving Genetic Testing Conflicts. The American Journal of Bioethics: Vol. 1, No. 3, pp. 28-29.

This article contributes to the revision of the procedure of robustness analysis of mathematical models in epistemic democracy using the systematic review method. It identifies the drawbacks of robustness analysis in epistemic democracy in terms of sample universality and inference from samples with the same results. To exemplify the effectiveness of systematic review, this article conducted a pilot review of diversity trumps ability theorem models, which are mathematical models of deliberation often cited by epistemic democrats. A review of (...) nine models extracted from 352 papers exemplifies the effectiveness of robustness analysis supplemented by systematic review in epistemic democracy. (shrink)

Rene Descartes (1596 – 1650) is considered the founder of modern philosophy. Profoundly influenced by the new physics and astronomy of Kepler and Galileo, Descartes was a scientist and mathematician whose most long-lasting contributions in science were the invention of Cartesian coordinates, the application of algebra to geometry, and the discovery of the law of refraction, what we now call Snell’s law.His most important books on philosophy were The discourse on method(1637) and The meditations(1642). Descartes’ writings display an exemplary degree (...) of clarity and an aversion to pedantry. I explore Descartes' break with Aristotle, but also shine a light on the intellectual continuity Descartes had with Aristotle's thought. I also draw attention to some overlooked but interesting possibilities for an experimental test of a dualistic theory of mind. (shrink)

The article presents a verbal and mathematical model of medium-term business cycles (with a characteristic period of 7–11 years) known as Juglar cycles. The model takes into account a number of approaches to the analysis of such cycles; in the meantime it also takes into account some of the authors' own generalizations and additions that are important for understanding the internal logic of the cycle, its variability and its peculiarities in the present-time conditions. The authors argue that the most (...) important cause of cyclical crises stems from strong structural disproportions that develop during economic booms. These are not only disproportions between different economic sectors, but also disproportions between different societal subsystems; at present these are also disproportions within the World System as a whole. The proposed model of business cycle is based on its subdivision into four phases: – recovery phase (which could be subdivided into the start sub-phase and the acceleration sub-phase); – upswing/prosperity/expansion phase (which could be subdivided into the growth sub-phase and the boom/overheating sub-phase); – recession phase (within which one may single out the crash/bust/acute crisis subphase and the downswing sub-phase); – depression/stagnation phase (which we could subdivide into the stabilization subphase and the breakthrough sub-phase). The article provides a detailed qualitative description of macroeconomic dynamics at all the phases; it specifies driving forces of cyclical dynamics and the causes of transition from one phase to another (including psychological causes); a special attention is paid to the turning point from the peak of overheating to the acute crisis, as well as to the turning point from the downswing to recovery. The proposed mathematical model of Juglar cycle takes into account the following effects that are typical for the market economy: • positive feedbacks between various economic processes; • presence of a certain inertia, time lags in reactions of the economic subsystem to the change in conditions; • amplification by the financial subsystem of positive feedbacks and time lags in the economic subsystem; • excessive reaction to changing conditions during the acute crisis sub-phase. The authors suggest that the current crisis turns out to be rather similar to classical Juglar crises; however, there is also a significant difference, as the current crisis occurs at a truly global scale. Yet, due to this truly global scale of the current crisis, the possibilities of regulation with the national state's measures have turned out to be ineffective,whereas the suprastate regulation of financial processes hardly exists. It is shown that all these have led to the reproduction of the current crisis according to a classical Juglar scenario. (shrink)

In his classic 1936 essay "On the Concept of Logical Consequence", Alfred Tarski used the notion of satisfaction to give a semantic characterization of the logical properties. Tarski is generally credited with introducing the model-theoretic characterization of the logical properties familiar to us today. However, in his book, The Concept of Logical Consequence, Etchemendy argues that Tarski's account is inadequate for quite a number of reasons, and is actually incompatible with the standard model-theoretic account. Many of his criticisms are meant (...) to apply to the model-theoretic account as well. In this paper, I discuss the following four critical charges that Etchemendy makes against Tarski and his account of the logical properties: (1) (a) Tarski's account of logical consequence diverges from the standard model-theoretic account at points where the latter account gets it right. (b) Tarski's account cannot be brought into line with the model-theoretic account, because the two are fundamentally incompatible. (2) There are simple counterexamples (enumerated by Etchemendy) which show that Tarski's account is wrong. (3) Tarski committed a modal fallacy when arguing that his account captures our pre-theoretical concept of logical consequence, and so obscured an essential weakness of the account. (4) Tarski's account depends on there being a distinction between the "logical terms" and the "non-logical terms" of a language, but (according to Etchemendy) there are very simple (even first-order) languages for which no such distinction can be made. Etchemendy's critique raises historical and philosophical questions about important foundational work. However, Etchemendy is mistaken about each of these central criticisms. In the course of justifying that claim, I give a sustained explication and defense of Tarski's account. Moreover, since I will argue that Tarski's account and the model theoretic account really do come to the same thing, my subsequent defense of Tarski's account against Etchemendy's other attacks doubles as a defense against criticisms that would apply equally to the familiar model-theoretic account of the logical properties. (shrink)

John P. Burgess, Mathematics, Models, and Modality: Selected Philosophical Essays. Cambridge: Cambridge University Press, 2008. xiii + 301 pp. $90.00, £50.00. ISBN 978-0-521-88034-3. Adobe eBook, $...

A version of nonstandard analysis, Internal Set Theory, has been used to provide a resolution of Zeno's paradoxes of motion. This resolution is inadequate because the application of Internal Set Theory to the paradoxes requires a model of the world that is not in accordance with either experience or intuition. A model of standard mathematics in which the ordinary real numbers are defined in terms of rational intervals does provide a formalism for understanding the paradoxes. This model suggests that in (...) discussing motion, only intervals, rather than instants, of time are meaningful. The approach presented here reconciles resolutions of the paradoxes based on considering a finite number of acts with those based on analysis of the full infinite set Zeno seems to require. The paper concludes with a brief discussion of the classical and quantum mechanics of performing an infinite number of acts in a finite time. (shrink)

If one investigates a process that has several causes but assumes that it has only one cause, one risks ruling out important causal factors. Three mechanisms account for this mistake: either the significance of the single cause under test is masked by noise contributed by the unsuspected and uncontrolled factors, or the process appears only when two or more causes interact, or the process appears when there are present any of a number of sufficient causes which are not mutally exclusive. (...) In ecology and evolutionary biology, experiments usually test single factor hypotheses, and many scientists apparently believe that hypotheses incorporating several factors are so much more difficult to test that to do so would not be practical. We discuss several areas in ecology and evolutionary biology in which the presupposition of simple causation has apparently impeded progress. We also examine a more mature field, the study of atherosclerosis, in which single factor studies did significantly delay progress towards understanding what now appears to be a multifactor process. The problem has three solutions: either factorial experiments, dynamic models that make quantitative predictions, response-surface methods, or all three. In choosing a definition for ‘cause’, we make a presupposition that profoundly influences subsequent observations and experimental designs. Alternative definitions of causation should be considered as contributing to potential cures for research problems. (shrink)

A reasoned argument or tarka is essential for a wholesome vāda that aims at establishing the truth. A strong tarka constitutes of a number of elements including an anumāna based on a valid hetu. Several scholars, such as Dharmakīrti, Vasubandhu and Dignāga, have worked on theories for the establishment of a valid hetu to distinguish it from an invalid one. This paper aims to interpret Dignāga’s hetu-cakra, called the wheel of grounds, from a modern philosophical perspective by deconstructing it into (...) a simple probabilistic mathematical model. The objective is to understand how and why a vāda based on a probabilistically weaker hetu can degrade into a Jalpa or vitaṇḍā. To do so, the paper maps the concept of ‘Bounded Rationality’ onto the hetu-cakra. Bounded Rationality, an idea coined by the management thinker Herbert Simon, is often employed in understanding decision-making processes of rational agents. In the context of this paper, the concept would state that the prativādin and ālocaka (debater) may not hold unbounded information to back their pratijñā (proposition). The paper argues that within the probabilistically deconstructed hetu-cakra model, most people argue in the ‘Zone of Bounded Rationality’, and thus, the probability of a debate degrading into Jalpa or vitaṇḍā is high. -/- . (shrink)

In the present article we attempt to show that Aristotle's syllogistic is an underlying logiC which includes a natural deductive system and that it isn't an axiomatic theory as had previously been thought. We construct a mathematical model which reflects certain structural aspects of Aristotle's logic. We examine the relation of the model to the system of logic envisaged in scattered parts of Prior and Posterior Analytics. Our interpretation restores Aristotle's reputation as a logician of consummate imagination and skill. (...) Several attributions of shortcomings and logical errors to Aristotle are shown to be without merit. Aristotle's logic is found to be self-sufficient in several senses: his theory of deduction is logically sound in every detail. (His indirect deductions have been criticized, but incorrectly on our account.) Aristotle's logic presupposes no other logical concepts, not even those of propositional logic. The Aristotelian system is seen to be complete in the sense that every valid argument expressible in his system admits of a deduction within his deductive system: every semantically valid argument is deducible. (shrink)

Mathematics is obviously important in the sciences. And so it is likely to be equally important in any effort that aims to understand God in a scientifically significant way or that aims to clarify the relations between science and theology. The degree to which God has any perfection is absolutely infinite. We use contemporary mathematics to precisely define that absolute infinity. For any perfection, we use transfinite recursion to define an endlessly ascending series of degrees of that perfection. That series (...) rises to an absolutely infinite degree of that perfection. God has that absolutely infinite degree. We focus on the perfections of knowledge, power, and benevolence. Our model of divine infinity thus builds a bridge between mathematics and theology. (shrink)

A practical viewpoint links reality, representation, and language to calculation by the concept of Turing (1936) machine being the mathematical model of our computers. After the Gödel incompleteness theorems (1931) or the insolvability of the so-called halting problem (Turing 1936; Church 1936) as to a classical machine of Turing, one of the simplest hypotheses is completeness to be suggested for two ones. That is consistent with the provability of completeness by means of two independent Peano arithmetics discussed in Section (...) I. Many modifications of Turing machines cum quantum ones are researched in Section II for the Halting problem and completeness, and the model of two independent Turing machines seems to generalize them. Then, that pair can be postulated as the formal definition of reality therefore being complete unlike any of them standalone, remaining incomplete without its complementary counterpart. Representation is formal defined as a one-to-one mapping between the two Turing machines, and the set of all those mappings can be considered as “language” therefore including metaphors as mappings different than representation. Section III investigates that formal relation of “reality”, “representation”, and “language” modeled by (at least two) Turing machines. The independence of (two) Turing machines is interpreted by means of game theory and especially of the Nash equilibrium in Section IV. Choice and information as the quantity of choices are involved. That approach seems to be equivalent to that based on set theory and the concept of actual infinity in mathematics and allowing of practical implementations. (shrink)

This comprehensive analysis dives deep into the intricate interplay between artificial intelligence (AI) and human agency, examining the remarkable capabilities and inherent limitations of large language models (LLMs) such as GPT-3 and ChatGPT. The paper traces the complex trajectory of AI's evolution, highlighting its operation based on statistical pattern recognition, devoid of self-consciousness or innate comprehension. As AI permeates multiple spheres of human life, it raises substantial ethical, legal, and societal concerns that demand immediate attention and deliberation. The metaphorical illustration (...) of humans as “shepherds” of AI, coupled with a thought-provoking examination of “agency without intelligence,” engenders deep reflections on the future of human-AI interplay and the associated philosophical, ethical, and practical ramifications. The paper further elucidates critical challenges associated with AI, such as ethical dilemmas, “agency without intelligence,” the role of human oversight, and the environmental impact of AI technologies. In the pursuit of solutions, the paper maps prospective directions, emphasizing the need for robust AI policies, improved AI literacy, sustainable AI practices, and a continued dialogue on the multifaceted issues surrounding AI. Through a holistic exploration of AI, this paper underlines the necessity for a multidisciplinary, collaborative approach to chart an ethical, beneficial, and sustainable AI future, enabling society to harness the potential of AI responsibly while mitigating the associated risks. (shrink)

The article presents three models of radical cultural practice: Adorno’s dissonant modernism, Brecht’s “functional transformation” or “re-functioning” of institutions through estrangement and dialectical realism, and Debord’s Situationist détournement of art, aiming to rupture and decolonize naturalized everyday life. The three models all begin with a critical appropriation of the traditions of art and aims at resisting the social power that passes through art, as an institutionalized field of production and activity. Each of the three modes establishes a set of productive (...) strategies. (shrink)

We review mathematical models of HIV dynamics, disease progression, and therapy. We start by introducing a basic model of virus infection and demonstrate how it was used to study HIV dynamics and to measure crucial parameters that lead to a new understanding of the disease process. We discuss the diversity threshold model as an example of the general principle that virus evolution can drive disease progression and the destruction of the immune system. Finally, we show how mathematical models (...) can be used to understand correlates of long‐term immunological control of HIV, and to design therapy regimes that convert a progressing patient into a state of long‐term non‐progression. BioEssays 24:1178–1187, 2002. © 2002 Wiley‐Periodicals, Inc. (shrink)

Games of chance are developed in their physical consumer-ready form on the basis of mathematical models, which stand as the premises of their existence and represent their physical processes. There is a prevalence of statistical and probabilistic models in the interest of all parties involved in the study of gambling – researchers, game producers and operators, and players – while functional models are of interest more to math-inclined players than problem-gambling researchers. In this paper I present a structural analysis (...) of the knowledge attached to mathematical models of games of chance and the act of modeling, arguing that such knowledge holds potential in the prevention and cognitive treatment of excessive gambling, and I propose further research in this direction. (shrink)

First published in 1999. Routledge is an imprint of Taylor & Francis, an informa company.

We have developed a simple mathematical model with three physiologically significant states to describe the changes in intrauterine pressure associated with a contraction during human parturition. The myometrium is modelled as a set of smooth muscle cells, each of which is in one of three states (quiescent, contracted, refractory) at a given time. These states are occupied according to a cycle governed by three temporal parameters. The solutions of the equations describing the model show an oscillatory behavior for particular (...) values of these parameters, which is very similar to the time dependant development of intrauterine pressure during labor. Due to its non-linear terms, our model could lead to chaotic oscillations (in the mathematical sense), whose clinical counterpart may occur in cases of dystocia. Despite its simplicity, this model appears to be a useful guide to further investigations of the oscillatory behavior of the myometrium, or other smooth muscles, in normal and pathological situations. (shrink)

Scientists use models to know the world. It i susually assumed that mathematicians doing pure mathematics do not. Mathematicians doing pure mathematics prove theorems about mathematical entities like sets, numbers, geometric figures, spaces, etc., they compute various functions and solve equations. In this paper, I want to exhibit models build by mathematicians to study the fundamental components of spaces and, more generally, of mathematical forms. I focus on one area of mathematics where models occupy a central role, namely (...) homotopy theory. I argue that mathematicians introduce genuine models and I offer a rough classification of these models. (shrink)

Metaphor influences the construction of biological models and theories and the analysis of its use can reveal important tools of thought. Some aspects of biological organisation are investigated through the analysis of metaphors associated with treating biosystems as a kind of text. In particular, the use of glue and verbs is considered. Some of the reasons why glue is important in the construction of hierarchies are pursued in the light of specific examples, and some of the conceptual links between glue (...) in biology and other domains is discussed. Verbs are shown to be important in the construction of networks. Some of the relations between glue, verb and text are considered and the text metaphor is placed within a much broader context of ideas associated with form, relation and system. The paper concludes with comments on the nature of biological information and the need for extending or better understanding the verbal vocabulary. (shrink)

Through the use of Bayesian probability theory and Communication theory, a formal mathematical model of a Churchmanian Dialectical Inquirer is developed. The Dialectical Inquirer is based on Professor C. West Churchman's novel interpretation and application of Hegelian dialectics to decision theory. The result is not only the empirical application of dialectical inquiry but also its empirical (i.e., scientific) investigation. The Dialectical Inquirer is seen as especially suited to problems in strategic policy formation and in decision theory. Finally, specific application (...) of the inquirer is made to Popper's notions for ‘The Test of Severity’ of a scientific theory. (shrink)

The problem with model-theoretic modal semantics is that it provides only the formal beginnings of an account of the semantics of modal languages. In the case of non-modal language, we bridge the gap between semantics and mere model theory, by claiming that a sentence is true just in case it is true in an intended model. Truth in a model is given by the model theory, and an intended model is a model which has as domain the actual objects of (...) discourse, and which relates these objects in an appropriate manner. However, the same strategy applied to the modal case seems to require an intended modal model whose domain includes mere possibilia. Building on recent work by Christopher Menzel (Synthese 85 (1990)), I give an account of model-theoretic semantics for modal languages which does not require mere possibilia or intensional entities of any kind. Menzel has offered a representational account of model-theoretic modal semantics that accords with actualist scruples, since it does not require possibilia. However, Menzel's view is in the company of other actualists who seek to eliminate possible worlds, but whose accounts tolerate other sorts of abstract, intensional entities, such as possible states of affairs. Menzel's account crucially depends on the existence of properties and relations in intension. I offer a purely extensional, representational account and prove that it does all the work that Menzel's account does. The result of this endeavor is an account of model theoretic semantics for modal languages requiring nothing but pure sets and the actual objects of discourse. Since ontologically beyond what is prima facie presupposed by the model theory itself. Thus, the result is truly an ontology-free model-theoretic semantics for modal languages. That is to say, getting genuine modal semantics out of the model theory is ontologically cost-free. Since my extensional account is demonstrably no less adequate, and yet is at the same time more ontologically frugal, it is certainly to be preferred. (shrink)

First published in 1999. Routledge is an imprint of Taylor & Francis, an informa company.

Chronic pain is one of the most disabling medical conditions globally, yet, to date, we lack a satisfying theoretical framework for research and clinical practice. Over the prior decades, several frameworks have been presented with biopsychosocial models as the most promising. However, in translation to clinical practice, these models are often applied in an overly reductionist manner, leaving much to be desired. In particular, they often fail to characterize the complexities and dynamics of the lived experience of chronic pain. Recently, (...) an enactive, affordance-based approach has been proposed, opening up new ways to view chronic pain. This model characterizes how the persistence of pain alters a person’s field of affordances: the unfolding set of action possibilities that a person perceives as available to them. The affordance-based model provides a promising perspective on chronic pain as it allows for a systematic investigation of the interactive relation between patients and their environment, including characteristic alterations in the experience of their bodies and the space they inhabit. To help bridge the gap from philosophy to clinical practice, we unpack in this paper the core concepts of an affordance-based approach to chronic pain and their clinical implications, highlighting aspects that have so far received insufficient attention. We do so with an analogy to playing video games, as we consider such comparative illustration a useful tool to convey the complex concepts in an affordance-based model and further explore central aspects of the lived experience of chronic pain. (shrink)

We present a mathematical bioeconomic model of a fishery with a variable price. The model describes the time evolution of the resource, the fishing effort and the price which is assumed to vary with respect to supply and demand. The supply is the instantaneous catch while the demand function is assumed to be a monotone decreasing function of price. We show that a generic market price equation (MPE) can be derived and has to be solved to calculate non trivial (...) equilibria of the model. This MPE can have 1, 2 or 3 equilibria. We perform the analysis of local and global stability of equilibria. The MPE is extended to two cases: an age-structured fish population and a fishery with storage of the resource. (shrink)

Rift Valley Fever is a vector-borne disease mainly transmitted by mosquito. To gain some quantitative insights into its dynamics, a deterministic model with mosquito, livestock, and human host is formulated as a system of nonlinear ordinary differential equations and analyzed. The disease threshold $$\mathcal{R}_0$$ is computed and used to investigate the local stability of the equilibria. A sensitivity analysis is performed and the most sensitive model parameters to the measure of initial disease transmission $$\mathcal{R}_0$$ and the endemic equilibrium are determined. (...) Both $$\mathcal{R}_0$$ and the disease prevalence in mosquitoes are more sensitive to the natural mosquito death rate, d m . The disease prevalence in livestock and humans are more sensitive to livestock and human recruitment rates, $$\Uppi_l$$ and $$\Uppi_h$$, respectively, suggesting isolation of livestock from humans is a viable preventive strategy during an outbreak. Numerical simulations support the analytical results in further exploring theoretically the long-term dynamics of the disease at the population level. (shrink)

In this essay I argue against I. Bernard Cohen's influential account of Newton's methodology in the Principia: the 'Newtonian Style'. The crux of Cohen's account is the successive adaptation of 'mental constructs' through comparisons with nature. In Cohen's view there is a direct dynamic between the mental constructs and physical systems. I argue that his account is essentially hypothetical-deductive, which is at odds with Newton's rejection of the hypothetical-deductive method. An adequate account of Newton's methodology needs to show how Newton's (...) method proceeds differently from the hypothetical-deductive method. In the constructive part I argue for my own account, which is model based: it focuses on how Newton constructed his models in Book I of the Principia. I will show that Newton understood Book I as an exercise in determining the mathematical consequences of certain force functions. The growing complexity of Newton's models is a result of exploring increasingly complex force functions (intra-theoretical dynamics) rather than a successive comparison with nature (extra-theoretical dynamics). Nature did not enter the scene here. This intra-theoretical dynamics is related to the 'autonomy of the models'. (shrink)

Product acceptance determination using similarity measure index by neutrosophic statistics / Muhammad Aslam and Rehan Ahmed Khan Sherwani -- New concepts of strongly edge irregular interval-valued neutrosophic graphs / A.A.Talebi, Hossein Rashmanlou and Masoomeh Ghasemi -- The link between neutrosophy and learning : through the related concepts of representation and compression / Philippe Schweizer -- Neutrosophic soft cubic M-subalgebras of B-algebras / Mohsin Khalid, Neha Andaleeb Khalid and Hasan Khalid -- Alpha, beta and gamma product of neutrosophic graphs / (...) Nasir Shah, Said Broumi, Abdul Raheem and Tahir Imran -- Neutrosophic cubic normal ideal and neutrosophic cubic closed normal ideal of PS-algebra / Mohsin Khalid, Hasan khalid and Neha Andaleeb Khalid -- Neutrosophic multisets : an overview / Vakkas Uluçay -- Neutrosophy as a model for knowledge : the influence of representative models on thinking / Philippe Schweizer -- When neutrosophic theory meets three-way decisions / Rui Ren, Chao Zhang and Deyu Li -- Neutrosophic economic order quantity model with more than one price breaks / R. Surya, M. Mullai and G. Madhan Kumar -- General non-square systems of linear equations in single-valued triangular neutrosophic number environment / S.A. Edalatpanah -- Hesitant neutrosophic soft set relations / Abhijit Saha -- Computer application of neutrosophic set operations / S. Saranya, M. Vigneshwaran, Said Broumi -- Triangular bipolar neutrosophic based transportation problem / Avishek Chakraborty -- Studying neutrosophic variables / Rafif Alhabib and Ahmad Salama -- Decision making for logistics center location selection in trapezoidal neutrosophic environment / Kalyan Mondal and Surapati Pramanik -- Weighted similarity measure and decision making model for clinical application of single valued neutrosophic set / R.Binu and P. Isaac -- Rough neutrosophic set : an overview / Surapati Pramanik -- Some new concepts on normalized SVTN-number and multiple criteria decision making / İrfan Deli and Emel Kırmızı Öztürk. (shrink)