In lieu of an abstract, here is a brief excerpt of the content:The 2008 Meeting of the Society for Buddhist-Christian StudiesPeter A. HuffThe Society for Buddhist-Christian Studies (SBCS) sponsored two sessions in conjunction with the 2008 annual meeting of the American Academy of Religion (AAR). The first session addressed the topic "Cognitive Science, Religious Practices, and Human Development: Buddhist and Christian Perspectives." The second session focused on the life and legacy of Trappist monk, spiritual writer, and interfaith pioneer Thomas Merton (...) (1915–1968).The first session, moderated by Sandra Costen Kunz (Phillips Theological Seminary), featured five papers probing the relationship between research in the natural and social sciences and lessons from the experience of Buddhist and Christian practice: "The Body and the Mind: Buddhist Bowing and Neuroscience," presented by Paula K. Arai (Louisiana State University) and coauthored with Sascha du Lac (Salk Institute for Biological Sciences); "Who Hears? A Zen Buddhist Perspective" by Robert Aitken Roshi, founder and retired Zen master of the Diamond Sangha in Honolulu (read by Ruben Habito, Southern Methodist University); "'Your Cell Will Teach You Everything': Old Wisdom, Modern Science, and the Art of Attention" by Noreen Herzfeld (St. John's University); "Verbal Imagining: Scientific Reflection on Visual Cognition in Light of Traditional Tibetan and Christian Theologies of the Image" by Thomas Cattoi (Jesuit School of Theology, Berkeley); and "Cognitive Error and Contemplative Practices: The Cultivation of Discernment in Mind and Heart" by Wesley J. Wildman (Boston University). Revised versions of three of these papers with an introductory essay by Prof. Costen Kunz are included in this issue of Buddhist-Christian Studies.The theme for the society's second session, chaired by Alice Keefe (University of Wisconsin), was "Thomas Merton Forty Years after His Death: Buddhist and Christian Perspectives." Four presenters examined and evaluated Merton's distinctive contributions to Buddhist-Christian relations, theological reflection, and interreligious dialogue. In her paper "Self-Surrender in Merton's Writings and Contemplative Psychology," Daijaku Judith Kinst (California Institute of Integral Studies) concentrated on the place of subjective transformation in Merton's thought, describing his [End Page 143] "great gift" to the literature on the contemplative life as the "fearless" rejection of self-centeredness in the practice of prayer and spiritual formation. "Thomas Merton Meets Tibetan Buddhism" by Judith Simmer-Brown (Naropa University) shed new light on the impact of the dzogchen ("great completion") tradition on Merton's evolving spirituality, particularly as expressed in the letters, speeches, and private documents included in the posthumously published Asian Journal of Thomas Merton (1973). In "Non-Dual Wisdom as Feminine: Sophia and Prajnaparamita in Merton's Poem 'Hagia Sophia,'" Paula Hirschboeck (Edgewood College) explored suggestive parallels between Christian mystical experience and Buddhist madhyamika teaching in Merton's long, dreamlike Marian hymn from the early 1960s. Kristin Johnston Largen (Lutheran Theological Seminary, Gettysburg) concluded the session with an analysis of the role of Buddhism-inspired insights in Merton's approach to soteriological questions, especially as seen in his changing attitudes toward traditional Christian doctrines of hell, purgatory, eschatology, and the human person.Between sessions, members and friends of the society participated in the annual SBCS/AAR field trip to a local site significant for its relevance to interdisciplinary Buddhist-Christian studies. This year members visited the Chicago Cultural Center of Soka Gakkai International-USA (SGI-USA), the Buddhist association for peace, culture, and education based on the teachings of thirteenth-century Japanese monk and reformer Nichiren Daishonin. Located at 1455 South Wabash Avenue in downtown Chicago, the cultural center serves as the primary facility for SGI-USA activities in the Midwest. Mr. Guy McCloskey, senior vice president, publisher, and member of the board of directors for SGI-USA, organized the event. The evening's program included a tour of the center's award-winning architecture, an informal overview of the aims and initiatives of SGI-USA, and a delicious dinner served by members of the organization. [End Page 144]Peter A. HuffCentenary College of LouisianaCopyright © 2009 University of Hawai'i Press... (shrink)

Corruption involves greed, money, and risky decision-making. We explore the love of money, pay satisfaction, probability of risk, and dishonesty across cultures. Avaricious monetary aspiration breeds unethicality. Prospect theory frames decisions in the gains-losses domain and high-low probability. Pay dissatisfaction (in the losses domain) incites dishonesty in the name of justice at the individual level. The Corruption Perceptions Index, CPI, signals a high-low probability of getting caught for dishonesty at the country level. We theorize that decision-makers adopt avaricious love-of-money aspiration (...) as a lens and frame dishonesty in the gains-losses domain (pay satisfaction-dissatisfaction, Level 1) and high-low probability (CPI, Level 2) to maximize expected utility and ultimate serenity. We challenge the myth: Pay satisfaction mitigates dishonesty across nations consistently. Based on 6500 managers in 32 countries, our cross-level three-dimensional visualization offers the following discoveries. Under high aspiration conditions, pay dissatisfaction excites the highest- (third-highest) avaricious justice-seeking dishonesty in high (medium) CPI nations, supporting the certainty effect. However, pay satisfaction provokes the second-highest avaricious opportunity-seizing dishonesty in low CPI entities, sustaining the possibility effect—maximizing expected utility. Under low aspiration conditions, high pay satisfaction consistently leads to low dishonesty, demonstrating risk aversion—achieving ultimate serenity. We expand prospect theory from a micro and individual-level theory to a cross-level theory of monetary wisdom across 32 nations. We enhance the S-shaped Curve to three 3-D corruption surfaces across three levels of the global economic pyramid, providing novel insights into behavioral economics, business ethics, the environment, and responsibility. (shrink)

Construction and Schemata in Mathematics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4..

This talk was given Monday 13 May 2002 at Monash University in Melbourne, Australia, and previously to summer visitors at the IBM Watson Research Center in 2001. There are no section titles; the displayed material is what I wrote on the whiteboard as I spoke.

This volume, an expanded edition of the philosophy of language issue of the journal Midwest Studies in Philosophy (1977), includes essays by some of the ...

We investigated the definition, prevalence, perceived prevalence and severity of, as well as justifications for and expected responses to, academic dishonesty at the graduate level in a sample of 246 graduate students, 49 faculty, and 20 administrators. Between 2.5% and 55.1% of students self-reported engaging in academically dishonest behaviors, depending on the nature of the behavior. Students and faculty rated 40 examples of academically dishonest behaviors similarly in terms of severity, but faculty tended to underestimate the prevalence of academic dishonesty. (...) Students and faculty also reported how they would idealistically and realistically expect themselves to respond to cheating situations. Students rated 21 behaviors in terms of their likeliness to increase or decrease academically dishonest behavior. Suggestions are given for developing a climate or culture of academic integrity to address academic dishonesty. (shrink)

This collection of essays focuses on a current issue of central important in contemporary philosophy, the relationship between philosophy and empirical studies. Explores in detail a range of examples which demonstrate how the older paradigm – philosophy as conceptual analysis – is giving way to a more varied set of models of philosophical work Each of the featured papers is a previously unpublished contribution by a major scholar.

The philosophy of language has emerged in the 20th century as a fundamental area of philosophic inquiry. It is unquestionably central to research in many other areas, and some have even suggested that it should now be seen as the foundation of philosophy.

Rich with historical and cultural value, these works are published unaltered from the original University of Minnesota Press editions.

This addition to the Midwest Studies in Philosophy series comprises the most recent volume on the philosophy of Ludwig Wittgenstein to date. Here 16 philosophers explore both the challenges Wittgenstein presented to philosophy as well as the responses to those challenges from such noted thinkers as Kripke. By addressing various questions raised by Wittgenstein's work, these original essays aim to illuminate in one way or another the impact Wittgenstein's legacy has had on 20th-century philosophy.

Transplantation experiments have shown that developing metazoan organs carry intrinsic information about their size and shape. Organ and body size are also sensitive to extrinsic cues provided by the environment, such as the availability of nutrients. The genetic and molecular pathways that contribute to animal size and shape are numerous, yet how they cooperate to control growth is mysterious. The recent identification and characterization of several mutations affecting growth in Drosophila melanogaster promises to provide insights. Many of these mutations affect (...) the extrinsic control of animal size; others affect the organ‐intrinsic control of pattern and size. In this review, we summarize the characteristics of some of these mutations and their roles in growth and size control. In addition, we speculate about possible connections between the extrinsic and intrinsic pathways controlling growth and pattern. BioEssays 24:54–64, 2002. © 2002 John Wiley & Sons, Inc. (shrink)

This work presents 26 essays that address the issue of moral concepts. Many of the essays contain examples that should make this volume suitable for teaching moral concepts in a college or university.

Truth and Its Deformities is the 32nd volume in the Midwest Studies in Philosophy series. It contains major new contributions on a range of topics related to the general theme of the volume by some of the most important philosophers writing on truth in recent years.

In recent years naturalism has become a focal point in the discussions of many contemporary philosophers. Philosophical Naturalism in the series Midwest Studies in Philosophy offers a broad sampling of previously unpublished essays that represent the current status of discussions of naturalism.

Although generally philosophers have put a high valuation on reason, increasingly the role of emotions in motivating action is being recognized. The essays in this volume explore the emotions from a variety of perspectives, ranging from Aristotelian views of the passions to the new findings of cognitive science, and from such diverse starting points as medieval literature and psychological studies.

Contemporary Perspectives on the History of Philosophy was first published in 1983. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions. The authors of the 27 appears in Volume 8, Midwest Studies in Philosophy,have established reputations as historians of philosophy, but their vantage point, here, is from "contemporary perspectives" - they use contemporary analytic skills to examine problems and issues considered by past philosophers. The (...) papers, arranged in historical order, fall into six groups: ancient philosophy (the Pythagoreans, Plato, and Aristotle); the seventeenth-century rationalists (Descartes, Leibniz and Spinoza); the empiricists (Locke, Berkeley, and Hume); Kant; the nineteenth century (Hegel, Schopenhauer, and Mill); and, in conclusion, an essay on Wittgenstein's Tractatus and two broad, retrospective papers entitled "Old Analyses of the Physical World and new Philosophies of Language" and "Moral Crisis and the History of Ethics.". (shrink)

Philosophy and Poetry is the 33rd volume in the Midwest Studies in Philosophy series. It begins with contributions in verse from two world class poets, JohnAshbery and Stephen Dunn, and an article by Dunn on the creative processthat issued in his poem. The volume features new work from an internationalcollection of philosophers exploring central philosophical issues pertinent topoetry as well as the connections between the two domains.

This volume in the Midwest Studies in Philosophy series contains 18 essays which discuss the range of of religious traditions which inform the discussion of contemporary issues.

The 21 essays collected in this volume of Midwest Studies in Philosophy question and debate the primary assumptions of science. These are its conception of an orderly universe; its ability to define; and its ability to explain. The contributors approach these topics from varying perspectives, including the historic development of our understanding of the scientific enterprise; the controversy of opposing paradigms; and the challenges raised by quantum mechanics.

Rich with historical and cultural value, these works are published unaltered from the original University of Minnesota Press editions.

This is Volume V in the series Midwest Studies in Philosophy In 1979 the University of Minnesota Press assumed publication of the annual Midwest Studies in ...

Presents essays (previously unpublished) by prominent philosophers on topics such as rationality and alien cultures, moral realism and social science, human sciences in the case of literature, Foucault's genealogical method, Vigotsky and artificial intelligence. No index. Annotation copyrighted by Book News, Inc., Portland, OR.

Film and the Emotions explores the complicated relationship between filmed entertainment, such as movies and television shows, and our capacity to feel emotions. This volume of The Midwest Studies in Philosophy covers topics such as the role of imagination in our capacity to respond emotionally to films, how emotions felt in response to films relate to emotions felt about real events, and the moral implications of responding emotionally to fictions, among others. This collection includes nineteen original articles from experts on (...) film and emotion, including Noel Carroll, Gregory Currie, Susan Feagin, Stacie Friend, Robert Hopkins, Peter Lamarque and Peter Goldie, Derek Matravers, Carl Plantinga, and Murray Smith. (shrink)

This volume of the classic series is devoted to the claims, arguments, and perspectives of the New Atheists. The volume collects original work on these topics of leading thinkers in the philosophy of religion, epistemology, and metaphysics, and philosophy of science. These studies are punctuated by an original short story by a leading novelist.

Topos Theory is a subject that stands at the junction of geometry, mathematical logic and theoretical computer science, and it derives much of its power from the interplay of ideas drawn from these different areas. Because of this, an account of topos theory which approaches the subject from one particular direction can only hope to give a partial picture; the aim of this compendium is to present as comprehensive an account as possible of all the main approaches and thereby to (...) demonstrate the overall unity of the subject. The material is organised in such a way that readers interested in following a particular line of approach may do so by starting at an appropriate point in the text. (shrink)

Topos Theory is an important branch of mathematical logic of interest to theoretical computer scientists, logicians and philosophers who study the foundations of mathematics, and to those working in differential geometry and continuum physics. This compendium contains material that was previously available only in specialist journals. This is likely to become the standard reference work for all those interested in the subject.

Topos Theory is a subject that stands at the junction of geometry, mathematical logic and theoretical computer science, and it derives much of its power from the interplay of ideas drawn from these different areas. Because of this, an account of topos theory which approaches the subject from one particular direction can only hope to give a partial picture; the aim of this compendium is to present as comprehensive an account as possible of all the main approaches and thereby to (...) demonstrate the overall unity of the subject. The material is organised in such a way that readers interested in following a particular line of approach may do so by starting at an appropriate point in the text. (shrink)

By a classifying topos for a first-order theory , we mean a topos such that, for any topos models of in correspond exactly to open geometric morphisms → . We show that not every first-order theory has a classifying topos in this sense, but we characterize those which do by an appropriate ‘smallness condition’, and we show that every Grothendieck topos arises as the classifying topos of such a theory. We also show that every first-order theory has a conservative extension (...) to one which possesses a classifying topos, and we obtain a Heyting-valued completeness theorem for infinitary first-order logic. (shrink)

Having a confirmation bias sometimes leads us to hold inaccurate beliefs. So, the puzzle goes: why do we have it? According to the influential argumentative theory of reasoning, confirmation bias emerges because the primary function of reason is not to form accurate beliefs, but to convince others that we’re right. A crucial prediction of the theory, then, is that confirmation bias should be found only in the reasoning domain. In this article, we argue that there is evidence that confirmation bias (...) does exist outside the reasoning domain. This undermines the main evidential basis for the argumentative theory of reasoning. In presenting the relevant evidence, we explore why having such confirmation bias may not be maladaptive. (shrink)

Which systems/organisms are conscious? New tests for consciousness (‘C-tests’) are urgently needed. There is persisting uncertainty about when consciousness arises in human development, when it is lost due to neurological disorders and brain injury, and how it is distributed in nonhuman species. This need is amplified by recent and rapid developments in artificial intelligence (AI), neural organoids, and xenobot technology. Although a number of C-tests have been proposed in recent years, most are of limited use, and currently we have no (...) C-tests for many of the populations for which they are most critical. Here, we identify challenges facing any attempt to develop C-tests, propose a multidimensional classification of such tests, and identify strategies that might be used to validate them. (shrink)

© Copyright 2015, Mary Ann Liebert, Inc..Signal transducer and activator of transcription factor 3 is hyperactivated in head and neck squamous cell carcinomas. Cumulative evidence indicates that IL-6 production by HNSCC cells and/or stromal cells in the tumor microenvironment activates STAT3 and contributes to tumor progression and drug resistance. A library of 94,491 compounds from the Molecular Library Screening Center Network was screened for the ability to inhibit interleukin-6 -induced pSTAT3 activation. For contractual reasons, the primary high-content screening campaign was (...) conducted over several months in 3 distinct phases; 1,068 primary HCS actives remained after cytotoxic or fluorescent outliers were eliminated. One thousand one hundred eighty-seven compounds were cherry-picked for confirmation; actives identified in the primary HCS and compounds selected by a structural similarity search of the remaining MLSCN library using hits identified in phases I and II of the screen. Actives were confirmed in pSTAT3 IC50 assays, and an IFNγ-induced pSTAT1 activation assay was used to prioritize selective inhibitors of STAT3 activation that would not inhibit STAT1 tumor suppressor functions. Two hundred three concentration-dependent inhibitors of IL-6-induced pSTAT3 activation were identified and 89 of these also produced IC50s against IFN-γ-induced pSTAT1 activation. Forty-nine compounds met our hit criteria: they reproducibly inhibited IL-6-induced pSTAT3 activation by ≥70% at 20 μM; their pSTAT3 activation IC50s were ≤25 μM; they were ≥2-fold selective for pSTAT3 inhibition over pSTAT1 inhibition; a cross target query of PubChem indicated that they were not biologically promiscuous; and they were ≥90% pure. Twenty-six chemically tractable hits that passed filters for nuisance compounds and had acceptable drug-like and ADME-Tox properties by computational evaluation were purchased for characterization. The hit structures were distributed among 5 clusters and 8 singletons. Twenty-four compounds inhibited IL-6-induced pSTAT3 activation with IC50s ≤20 μM and 13 were ≥3-fold selective versus inhibition of pSTAT1 activation. Eighteen hits inhibited the growth of HNSCC cell lines with average IC50s ≤ 20 μM. Four chemical series were progressed into lead optimization: the guanidinoquinazolines, the triazolothiadiazines, the amino alcohols, and an oxazole-piperazine singleton. (shrink)