Francis Bacon, lawyer, statesman, and philosopher, remains one of the most effectual thinkers in European intellectual history. We can trace his influence from Kant in the 1700s to Darwin a century later. The Advancement of Learning , first published in 1605, contains an unprecedented and thorough systematization of the whole range of human knowledge. Bacon’s argument that the sciences should move away from divine philosophy and embrace empirical observation would forever change the way philosophers and natural scientists interpret their (...) world. (shrink)

This volume presents a survey exploring the profound influence of Socrates on the history of Western philosophy. It also discusses the life of Socrates and key philosophical doctrines associated with him.

Scepticism in the Sixth Century? Damascius' Doubts and Solutions Concerning First Principles SARA RAPPE THE Doubts and Solutions Concerning First Principles, an aporetic work of the sixth century Neoplatonist Damascius, is distinguished above all by its dialectical subtlety. Although the Doubts and Solutions belongs to the commentary tradi- tion on Plato's Parmenides, its structure and method make it in many ways unique among such exegetical works. The treatise positions itself, at least in part, as a response to Proclus' metaphysical system. (...) Thus the first principles alluded to in its title refer to a metaphysical structure consisting of five central elements, the Ineffable, the One, and the Noetic Triad, which Damascius both adumbrates in opposition to Proclus' as well as subjects to his own, internal critique. In this article, I will be asking whether or not Damascius' critique of Neoplatonic metaphysics is informed or inspired by ancient Scepticism. No doubt this question catches the reader off guard: if the last exponent of an- cient Scepticism is Sextus Empiricus, how could this sixth-century Neo- platonist Scholarch, the last officially appointed Platonic Successor, revert to a tradition that seemingly disappears for well over three centuries? ~ In what ~As is well known, Damascius modifies Proclus' own exposition of the Parmenidean hypothe- ses, positing a first principle to which he gives the title ~the Ineffable." For those interested in a.. (shrink)

This collection of qualitative case studies demonstrates how social groups create opposing symbolic meanings of Nature during conflict over wildlife issues. It highlights the untapped utility of constructionist approaches for understanding how different meanings can ultimately affect wildlife and people.

In lieu of an abstract, here is a brief excerpt of the content:Scepticism in the Sixth Century? Damascius’ Doubts and Solutions Concerning First PrinciplesSara RappeThe Doubts and Solutions Concerning First Principles, an aporetic work of the sixth century Neoplatonist Damascius, is distinguished above all by its dialectical subtlety. Although the Doubts and Solutions belongs to the commentary tradition on Plato’s Parmenides, its structure and method make it in many ways unique among such exegetical works. The treatise positions itself, at least (...) in part, as a response to Proclus’ metaphysical system. Thus the first principles alluded to in its title refer to a metaphysical structure consisting of five central elements, the Ineffable, the One, and the Noetic Triad, which Damascius both adumbrates in opposition to Proclus1 as well as subjects to his own, internal critique. In this article, I will be asking whether or not Damascius’ critique of Neoplatonic metaphysics is informed or inspired by ancient Scepticism. No doubt this question catches the reader off guard: if the last exponent of ancient Scepticism is Sextus Empiricus, how could this sixth-century Neoplatonist Scholarch, the last officially appointed Platonic Successor, revert to a tradition that seemingly disappears for well over three centuries?2 In what [End Page 337] follows, I suggest that a plausible historical context for such a reversion can be found in contemporaneous Neoplatonic allusions to Sceptical readings of Plato. I then analyze the Sceptical techniques deployed by Damascius in his critique of Neoplatonist metaphysics, focusing especially on his attacks on Neoplatonic theories of intellect and causation. I conclude by speculating on some ideological factors that shaped Damascius’ Sceptical affiliations, suggesting that here it is possible to see an initial volley in what was to become a centuries-long skirmish between reason and revelation.1. the neoplatonists read the sceptics?R. T. Wallis has suggested that Plotinus borrows from the Sceptics’ arsenal in voicing his own objections against Stoic or Stoicizing epistemology and theology. The seemingly radical stance that Plotinus takes against Stoic notions of divine rationality, virtue, and providence is anticipated by the Sceptics’ refusal to grant that an omniscient mind could stand in need of rational deliberation or exercise virtues that imply the presence of corresponding vices, etc. Not only is it the case that Plotinus makes a detailed use of specific Sceptical arguments in his own polemics against the Stoics, he seems to have been the first philosopher to have grasped the implications of Sceptical challenges to Stoic theology, and to have circumvented Sceptical dilemmas by means of his highly original formulations of nondiscursive thinking and negative theology.That this Platonist might side with Sceptics against dogmatic philosophy would hardly be surprising to the modern student of Plato, but it is also true that historically, this has been an uneasy alliance. In fact, it is just this question, the alliance between Platonists and the Sceptics, that gets rehearsed in the sixth century. Olympiodorus devotes Chapter 10 of his Prolegomena to the Study of Platonic Philosophy to the refutation of an ephectic, or nondogmatic Plato3: “Plato also superseded the philosophy of the New Academy since that school gave precedence to akatalepsia (nonapprehension), while Plato demonstrated that there do exist cognitions grounded in genuine knowledge. Nevertheless, some assert, assimilating Plato to the ephectics and to the Academicians, that he too maintained the doctrine of akatalepsia.” These remarks are curious, for we have no indication that a Sceptical reading of Plato was current or even conceivable at this time. In fact, as the context makes clear, the Sceptics are represented in this passage as a prior philosophical school; chapters 7 through 10 present a concise history of philosophy that is remarkably free from any notions of philosophical currency attributable to any of the views that fall [End Page 338] under its purvue: “there has been no shortage of philosophical haireseis [schools] both before and after Plato, yet he surpassed all of them by his teaching, his thought, and in every possible way”4 (Prolegomena, 7.1).Olympiodorus performs the exegete’s role throughout his refutation of a non-dogmatic Plato, turning first to the grammatical item, Plato’s use of what Olympiodorus terms the “hestitating” adverbs, such as “probably,” “perhaps,” and “as I imagine.” Nevertheless Olympiodorus manages... (shrink)

This is the first critical edition since the nineteenth century of Bacon's principal philosophical work in English, The Twoo Bookes of Francis Bacon. Of the proficience and advancement of Learning, divine and humane - traditionally known as The Advancement of Learning.

Damascius was head of the Neoplatonist academy in Athens when the Emperor Justinian shut its doors forever in 529. His work, Problems and Solutions Concerning First Principles, is the last surviving independent philosophical treatise from the Late Academy. It has never before been translated into English.

Professor d’Hoine claims that Proclus assigns a specific ontological function to the Form of Likeness in his Commentary on the Parmenides. According to d’Hoine, for Proclus, each individual must, qua individual striving to imitate the form, present a difference; this difference or unlikeness of one member of a coordinate kind to another, the plurality of participants in a Form, is Form’s by the Form of Unlikeness. And in a similar way, the Form of Likeness then guarantees the imitation of the (...) Form by the particular. I try to show that in other passages in Proclus’ oeuvre, likeness extends to include many more relationships than the Forms instantiation as a material particular. Hence, Likeness is not confined to this specific ontological function. (shrink)

This chapter contains sections titled: Introduction: Plato in Late Antiquity Middle Platonisms Neoplatonism Late Athenian Neoplatonism The Harmony of Plato and Aristotle Al‐Farabi Redivivus: Leo Strauss Epilogue: al‐Suhrawardi's Return to Plato Note.

[opening paragraph] -- Clark: The `astonishing hypothesis' which you put forward in your book, and which you obviously feel is very controversial, is that `You, your joys and sorrows, your memories and ambitions, your sense of personal identity and free will are, in fact, no more than the behaviour of a vast assembly of nerve cells. As Lewis Carroll's Alice might have phrased it: `You're nothing but a pack of neurons'.' But it seems to me that this is not so (...) astonishing a statement for a scientist to make. Isn't this what reductionist science has always believed? (shrink)

This far-ranging collection of essays represents a conference of the same name held at Emory University in conjunction with a meeting of the “Rethinking Plato’s Parmenides” seminar sponsored by the Society of Biblical Literature.In embracing authors as diverse as Plato himself, Epictetus, Ralph Cudworth, Yeats, and Levinas, to name a few of the Platonists identified herein, the volume clearly and deliberately stretches the meaning of this rubric to its outer limits. This review will reprise some of the articles from each (...) of the book’s sections—Ancient, Late Antique, Renaissance and Modern, and Post-modern Platonisms—in an effort to help readers gauge the argument of the book, which may or may not be endorsed by each of the individual contributors. The editors, at least in compiling this anthology, do so in the belief that Platonism might better be considered “as an inexhaustible mine of possible trajectories each of which helps us to see the richness of Platonic texts,” rather than “as a series of determinate doctrines” .Thomas Slezak opens the volume with a rehearsal of his programmatic way of reading Plato’s dialogues, involving two possibly competing claims: what Plato means by philosophy is not contained within the. (shrink)

Bradley's metaphysical views, akin to those of Hegel, with a special emphasis on the internal relations of the Absolute are developed at length in Appearance ...

Neoplatonism is a term used to designate the form of Platonic philosophy that developed in the Roman Empire from the third to the fifth century AD and that based itself on the corpus of Plato's dialogues. Sara Rappe's challenging and innovative study is the first book to analyse Neoplatonic texts themselves using contemporary philosophy of language. It covers the whole tradition of Neoplatonic writing from Plotinus through Proclus to Damascius. Addressing the strain of mysticism in these works from a fresh (...) perspective the author shows how these texts reflect actual meditational practices, methods of concentrating the mind, and other mental disciplines that informed the tradition as a whole. In providing the broadest available survey of Neoplatonic writing the book will appeal to classical philosophers, classicists, as well as students of religious studies. (shrink)

Argues that Socrates’s fundamental role in the dialogues is to guide us toward self-inquiry and self-knowledge. In this highly original and provocative book, Sara Ahbel-Rappe argues that the Platonic dialogues contain an esoteric Socrates who signifies a profound commitment to self-knowledge and whose appearances in the dialogues are meant to foster the practice of self-inquiry. According to Ahbel-Rappe, the elenchus, or inner examination, and the thesis that virtue is knowledge, are tools for a contemplative practice that teaches us how to (...) investigate the mind and its objects directly. In other words, the Socratic persona of the dialogues represents wisdom, which is distinct from and serves as the larger space in which Platonic knowledge—ethics, epistemology, and metaphysics—is constructed. Ahbel-Rappe offers complete readings of the Apology, Charmides, Alcibiades I, Euthyphro, Lysis, Phaedrus, Theaetetus, and Parmenides, as well as parts of the Republic. Her interpretation challenges two common approaches to the figure of Socrates: the thesis that the dialogues represent an “early” Plato who later disavows his reliance on Socratic wisdom, and the thesis that Socratic ethics can best be expressed by the construct of eudaimonism or egoism. (shrink)

Platonic discourses concerning the soul are incredibly rich and multitiered. Plato's own diverse and disparate arguments and images offer competing accounts of how we are to understand the nature of the soul. Consequently, it should come as no surprise that the accounts of Platonists who engage Plato’s dialogues are often riddled with questions. This volume takes up the theories of well-known philosophers and theologians, including Plato, Plotinus, Proclus, the emperor Julian, and Origen, as well as lesser-known but equally important figures (...) in a collection of essays on topics such as transmigration of the soul, the nature of the Platonist enlightenment experience, soul and gender, pagan ritual practices, Christian and pagan differences about the soul, mental health and illness, and many other topics. Contributors include Crystal Addey, Sara Ahbel-Rappe, Dirk Baltzly, Robert Berchman, Jay Bregman, Luc Brisson, Kevin Corrigan, John Dillon, John F. Finamore, Lloyd P. Gerson, Dorian Gieseler Greenbaum, Elizabeth Hill, Sarah Klitenic Wear, Danielle A. Layne, Ilaria L. E. Ramelli, Gregory Shaw, Svetla Slaveva-Griffine, Suzanne Stern-Gillet, Harold Tarrant, Van Tu, and John D. Turner. (shrink)

First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.

BackgroundConcurrent with efforts to establish national and regional biorepositories in Africa is widespread endorsement of ethics committees as stewards of the interests of individual donors and their communities. To date, ethics training programs for IRB members in Botswana have focused on ethical principles and international guidelines rather than on the ethical dimensions of specific medical technologies and research methodologies. Little is known about the knowledge and concerns of current and prospective IRB members in Botswana with respect to export, reuse, storage, (...) and benefit-sharing of biospecimens.MethodsThis qualitative study examined perspectives of IRB members in Botswana about the collection and use of biospecimens in research. Forty-one IRB members representing five committees in Botswana participated in discussions groups in March 2013. Transcriptions of audiotapes and field notes were analyzed to identify issues of concern that might be alleviated through education and capacity-building, and areas that required ongoing discussion or additional regulatory guidance.ResultsAreas of concern included lack of understanding among patients and providers about the use of biospecimens in clinical care and research; reuse of biospecimens, particularly issues of consent, ownership and decision-making; export of specimens and loss of control over reuse and potential benefits; and felt need for regulatory guidance and IRB-member training. Local belief systems about bodily integrity and strong national identity in the construct of benefits may be at odds with initiatives that involve foreign biorepositories or consider such collections to be global public goods.ConclusionEducation is needed to strengthen IRB-member capacity to review and monitor protocols calling for the collection and use of biospecimens, guided by clear national policy on priority-setting, partnerships, review, and oversight. Engagement with local stakeholders is needed to harmonize fundamentally different ways of understanding the human body and community identity with the aims of contemporary biomedicine. (shrink)

This article presents a review of the literature, summarizes current initiatives, and provides a heuristic for assessing the effectiveness of a range of institutional review board collaborative strategies that can reduce the regulatory burden of ethics review while ensuring protection of human subjects, with a particular focus on international research. Broad adoption of IRB collaborative strategies will reduce regulatory burdens posed by overlapping oversight mechanisms and has the potential to enhance human subjects protections.

BackgroundEthical and regulatory guidance on the collection and use of human biospecimens for research forms an essential component of national health systems in Sub-Saharan Africa, where rapid advances in genetic- and genomic-based technologies are fueling clinical trials involving HBS and the establishment of large-scale biobanks.MethodsAn extensive multi-level search for publicly available ethics regulatory guidance was conducted for each SSA country. A second review documented active trials listed in the WHO International Clinical Trials Registry Platform as of January 2015 in which (...) HBS collection was specified in the protocol. Findings were combined to determine the extent to which countries that are study sites for HBS-related research are supported by regulatory guidance language on the collection, use, ownership and storage of biospecimens.ResultsOf the 49 SSA countries, 29 had some form of national ethics guidance, yet only 17 provided language relating to HBS-related research, with specific guidance on consent, ownership, reuse, storage, and export/import/transfer. Ten countries accounted for 84 % of the active clinical trials involving the collection of HBS in SSA. All except one of these countries were found to have some national guidance in the form of regulations, codes of ethics, and/or standard operating procedures; however, only seven of the ten offered any language specific to HBS.ConclusionsDespite the fact that the bulk of registered clinical trials in SSA involving HBS, as well as existing and proposed sites for biorepositories under the H3Africa Initiative, are currently situated in countries with the most complete ethics and regulatory guidance, variability in the regulations themselves may create challenges for planned and future pan-African collaborations and may require legislative action at the national level to revise. Countries in SSA that still lack regulatory guidance on HBS will require extensive health system strengthening in ethics governance before they can be full participants in the modern research enterprise. (shrink)

First published in 1876, this forceful and vigorous classic of English moral philosophy, written in opposition to Utilitarianism by one of England's most eminent philosophers, is now available for the first time since 1977.

[opening paragraph] -- Clark: The `astonishing hypothesis' which you put forward in your book, and which you obviously feel is very controversial, is that `You, your joys and sorrows, your memories and ambitions, your sense of personal identity and free will are, in fact, no more than the behaviour of a vast assembly of nerve cells. As Lewis Carroll's Alice might have phrased it: `You're nothing but a pack of neurons'.' But it seems to me that this is not so (...) astonishing a statement for a scientist to make. Isn't this what reductionist science has always believed? (shrink)

THE LIFE Of FRANCIS BACON, LORD HIGH CHANCELLOR OF ENGLAND. THE ancient Egyptians had a law, which ordained that the actions and characters of their dead ...

First published in 1876, this forceful and vigorous classic of English moral philosophy, written in opposition to Utilitarianism by one of England's most eminent philosophers, is now available for the first time since 1977.

Noninvasive prenatal screening using cell-free DNA, which analyzes placental DNA circulating in maternal blood to provide information about fetal chromosomal disorders early in pregnancy and without risk to the fetus, has been hailed as a potential “paradigm shift” in prenatal genetic screening. Commercial provision of cell-free DNA screening has contributed to a rapid expansion of the tests included in the screening panels. The tests can include screening for sex chromosome anomalies, rare subchromosomal microdeletions and aneuploidies, and most recently, the entire (...) fetal genome. The benefits of this screening tool are generally framed, by both providers and commercial laboratories, as enhancing reproductive autonomy and choice by providing an earlier, simpler, and more accurate screening while potentially reducing the need for invasive follow-up testing. The majority of the literature has explored these issues empirically or conceptually from a European or North American vantage point, one that assumes normative priorities such as individual reproductive autonomy and the clinical availability of maternal health care or prenatal screening programs within which cell-free DNA screening is offered. While its implementation has raised both challenges and opportunities, very little is known about real-world experiences and the implications of the rapid introduction of cell-free DNA screening outside of North America and Europe, especially in low- and middle-income countries. To begin addressing this gap in knowledge, we organized a four-day international workshop to explore the ethical, legal, social, economic, clinical, and practical implications of the global expansion of cell-free DNA screening. We describe eight key insights that arose from the workshop. (shrink)

F. H. Bradley was the foremost philosopher of the British Idealist school, which came to prominence in the second half of the nineteenth century. Bradley, who was a life fellow of Merton College, Oxford, was influenced by Hegel, and also reacted against utilitarianism. He was recognised during his lifetime as one of the greatest intellectuals of his generation and was the first philosopher to receive the Order of Merit, in 1924. His work is considered to have been important to the (...) formation of analytic philosophy. In metaphysics, he rejected pluralism and realism, and believed that English philosophy needed to deal systematically with first principles. This work, first published in 1893, is divided into two parts: 'Appearance' deals with exposing the contradictions that Bradley believed are hidden in our everyday conceptions of the world; and in 'Reality', he builds his positive account of reality and considers possible objections to it. (shrink)