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    “The keeping is the problem”: A qualitative study of IRB-member perspectives in Botswana on the collection, use, and storage of human biological samples for research.Francis Barchi, Keikantse Matlhagela, Nicola Jones, Poloko M. Kebaabetswe & Jon F. Merz - 2015 - BMC Medical Ethics 16 (1):1-11.
    BackgroundConcurrent with efforts to establish national and regional biorepositories in Africa is widespread endorsement of ethics committees as stewards of the interests of individual donors and their communities. To date, ethics training programs for IRB members in Botswana have focused on ethical principles and international guidelines rather than on the ethical dimensions of specific medical technologies and research methodologies. Little is known about the knowledge and concerns of current and prospective IRB members in Botswana with respect to export, reuse, storage, (...)
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  2.  24
    Fostering IRB Collaboration for Review of International Research.Francis Barchi, Megan Kasimatis Singleton & Jon F. Merz - 2014 - American Journal of Bioethics 14 (5):3-8.
    This article presents a review of the literature, summarizes current initiatives, and provides a heuristic for assessing the effectiveness of a range of institutional review board collaborative strategies that can reduce the regulatory burden of ethics review while ensuring protection of human subjects, with a particular focus on international research. Broad adoption of IRB collaborative strategies will reduce regulatory burdens posed by overlapping oversight mechanisms and has the potential to enhance human subjects protections.
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  3.  26
    National ethics guidance in Sub-Saharan Africa on the collection and use of human biological specimens: a systematic review.Francis Barchi & Madison T. Little - 2016 - BMC Medical Ethics 17 (1):64.
    BackgroundEthical and regulatory guidance on the collection and use of human biospecimens for research forms an essential component of national health systems in Sub-Saharan Africa, where rapid advances in genetic- and genomic-based technologies are fueling clinical trials involving HBS and the establishment of large-scale biobanks.MethodsAn extensive multi-level search for publicly available ethics regulatory guidance was conducted for each SSA country. A second review documented active trials listed in the WHO International Clinical Trials Registry Platform as of January 2015 in which (...)
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