The amygdala is a key brain area regulating responses to stress and emotional stimuli, so improving our understanding of how it is regulated could offer novel strategies for treating disturbances in emotion regulation. As we review here, a growing body of evidence indicates that the gut microbiota may contribute to a range of amygdala-dependent brain functions from pain sensitivity to social behavior, emotion regulation, and therefore, psychiatric health. In addition, it appears that the microbiota is necessary for normal development of (...) the amygdala at both the structural and functional levels. While further investigations are needed to elucidate the exact mechanisms of microbiota-to-amygdala communication, ultimately, this work raises the intriguing possibility that the gut microbiota may become a viable treatment target in disorders associated with amygdala dysregulation, including visceral pain, post-traumatic stress disorder, and beyond. Also see the video abstract here: https://youtu.be/O5gvxVJjX18 The amygdala plays a central role in regulating many aspects of behavior in rodents and humans, from pain responding to social interaction and psychiatric function. Accumulating evidence suggests microbiota-to-amygdala communication along the gut-brain axis is a key modulator of these amygdala-dependent behaviors, with critical implications for health and disease. (shrink)

© 2016 Regents of the University of California.The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,062 new measurements from 721 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark photons, etc. All the particle properties and search limits are listed in Summary Tables. We also give numerous (...) tables, figures, formulae, and reviews of topics such as Higgs Boson Physics, Supersymmetry, Grand Unified Theories, Neutrino Mixing, Dark Energy, Dark Matter, Cosmology, Particle Detectors, Colliders, Probability and Statistics. Among the 117 reviews are many that are new or heavily revised, including those on Pentaquarks and Inflation. The complete Review is published online in a journal and on the website of the Particle Data Group. The printed PDG Book contains the Summary Tables and all review articles but no longer includes the detailed tables from the Particle Listings. A Booklet with the Summary Tables and abbreviated versions of some of the review articles is also available. (shrink)

Among several possibilities for what reality could be like in view of the empirical facts of quantum mechanics, one is provided by theories of spontaneous wave function collapse, the best known of which is the Ghirardi–Rimini–Weber theory. We show mathematically that in GRW theory there are limitations to knowledge, that is, inhabitants of a GRW universe cannot find out all the facts true of their universe. As a specific example, they cannot accurately measure the number of collapses that a given (...) physical system undergoes during a given time interval; in fact, they cannot reliably measure whether one or zero collapses occur. Put differently, in a GRW universe certain meaningful, factual questions are empirically undecidable. We discuss several types of limitations to knowledge and compare them with those in other versions of quantum mechanics, such as Bohmian mechanics. Most of our results also apply to observer-induced collapses as in orthodox quantum mechanics. 1 Introduction1.1 Known examples of limitations to knowledge1.2 Remarks2 Brief Review of GRW Theories2.1 The GRW process2.2 GRWm2.3 GRWf3 First Examples of Limitations to Knowledge in GRW Theories4 Measurements of Flashes in GRWf, or of Collapses in GRWm4.1 An example in which ψ is known4.2 Other choices of ψ4.3 Experiments beginning before t24.4 If ψ is random4.5 Optimal way of distinguishing two density matrices4.6 If ψ is unknown5 Measurements of m in GRWmAppendix. (shrink)

Contributors: Steven M. Cahn, James W. Nickel, J. L. Cowan, Paul W. Taylor, Michael D. Bayles, William A. Nunn III, Alan H. Goldman, Paul Woodruff, Robert A. Shiver, Judith Jarvis Thomson, Robert Simon, George Sher, Robert Amdur, Robert K. Fullinwider, Bernard R. Boxhill, Lisa H. Newton, Anita L. Allen, Celia Wolf-Devine, Sidney Hook, Richaed Waaserstrom, Thomas E. Hill, Jr., John Kekes.

We provide additional support for Cowan's claim that short term memory (STM) involves a range of 3–5 tokens, on the basis of language correlational analyses. If language is at least partly learned, linguistic dependency structure should reflect properties of the cognitive components mediating learning; one such component is STM. In this view, the range over which statistical regularity extends in ordinary text would be suggestive of STM span. Our analyses of eight languages are consistent with STM span being about (...) four chunks. (shrink)

Cowan postulates that the capacity of short-term memory is limited to the number of items to which attention can be simultaneously directed. Unfortunately, he endows attention with unexplained properties, such as being able to locate the most recent inputs to short-term memory, so his theory does little more than restate the data.

"This is one of the most interesting texts I have read for many years ... It is authoritative and clearly written. It provides a rich set of examples of teaching, and a reflective discourse." Professor George Brown "...succeeds in inspiring the reader by making the process of reflective learning interesting and thought provoking ... has a narrative drive which makes it a book too good to put down." Dr Mary Thorpe "...a delightful and unusual reflective journey...the whole book is driven (...) by a cycle of questions, examples, strategies and generalizations from the examples. In all, it is the clearest example of practise-what-you-preach that I have seen." Professor John Biggs This unusual, accessible and significant book begins each chapter by posing a question with which college and university teachers can be expected to identify; and then goes on to answer the question by presenting a series of examples; finally, each chapter closes with 'second thoughts', presenting a viewpoint somewhat distinct from that taken by John Cowan. This book will assist university teachers to plan and run innovative activities to enable their students to engage in effective reflective learning; it will help them adapt other teachers' work for use with their own students; and will give them a rationale for the place of reflective teaching and learning in higher education. (shrink)

This study described the relationships between academic class and student moral sensitivity and reasoning and between curriculum design components for ethics education and student moral sensitivity and reasoning. The data were collected from freshman (n = 506) and senior students (n = 440) in eight baccalaureate nursing programs in South Korea by survey; the survey consisted of the Korean Moral Sensitivity Questionnaire and the Korean Defining Issues Test. The results showed that moral sensitivity scores in patient-oriented care and conflict were (...) higher in senior students than in freshman students. Furthermore, more hours of ethics content were associated with higher principled thinking scores of senior students. Nursing education in South Korea may have an impact on developing student moral sensitivity. Planned ethics content in nursing curricula is necessary to improve moral sensitivity and moral reasoning of students. (shrink)

In this Introduction we introduce the central themes of the Evaluative Perception volume. After identifying historical and recent contemporary work on this topic, we discuss some central questions under three headings: (1) Questions about the Existence and Nature of Evaluative Perception: Are there perceptual experiences of values? If so, what is their nature? Are experiences of values sui generis? Are values necessary for certain kinds of experience? (2) Questions about the Epistemology of Evaluative Perception: Can evaluative experiences ever justify evaluative (...) judgments? Are experiences of values necessary for certain kinds of justified evaluative judgments? (3) Questions about Value Theory and Evaluative Perception: Is the existence of evaluative experience supported or undermined by particular views in value theory? Are particular views in value theory supported or undermined by the existence of value experience? (shrink)

Earlier versions of all the essays were given at a colloquium at Assumption College, Sept. 21-22, 2007.

Jeffery et al. propose a non-uniform representation of three-dimensional space during navigation. Fittingly, we recently revealed asymmetries between horizontal and vertical path integration in humans. We agree that representing navigation in more than two dimensions increases computational load and suggest that tendencies to maintain upright head posture may help constrain computational processing, while distorting neural representation of three-dimensional navigation.

Miller (1956) summarized evidence that people can remember about seven chunks in short-term memory (STM) tasks. However, that number was meant more as a rough estimate and a rhetorical device than as a real capacity limit. Others have since suggested that there is a more precise capacity limit, but that it is only three to five chunks. The present target article brings together a wide variety of data on capacity limits suggesting that the smaller capacity limit is real. Capacity limits (...) will be useful in analyses of information processing only if the boundary conditions for observing them can be carefully described. Four basic conditions in which chunks can be identified and capacity limits can accordingly be observed are: (1) when information overload limits chunks to individual stimulus items, (2) when other steps are taken specifically to block the recoding of stimulus items into larger chunks, (3) in performance discontinuities caused by the capacity limit, and (4) in various indirect effects of the capacity limit. Under these conditions, rehearsal and long-term memory cannot be used to combine stimulus items into chunks of an unknown size; nor can storage mechanisms that are not capacity-limited, such as sensory memory, allow the capacity-limited storage mechanism to be refilled during recall. A single, central capacity limit averaging about four chunks is implicated along with other, noncapacity-limited sources. The pure STM capacity limit expressed in chunks is distinguished from compound STM limits obtained when the number of separately held chunks is unclear. Reasons why pure capacity estimates fall within a narrow range are discussed and a capacity limit for the focus of attention is proposed. Key Words: attention; enumeration; information chunks; memory capacity; processing capacity; processing channels; serial recall; short-term memory; storage capacity; verbal recall; working memory capacity. (shrink)

A common objection to Sosa’s epistemology is that it countenances, in an objectionable way, unsafe knowledge. This objection, under closer inspection, turns out to be in far worse shape than Sosa’s critics have realised. Sosa and his defenders have offered two central response types to the idea that allowing unsafe knowledge is problematic: one response type adverts to the animal/reflective knowledge distinction that is characteristic of bi-level virtue epistemology. The other less-discussed response type appeals to the threat of dream scepticism, (...) and in particular, to the idea that many of our everyday perceptual beliefs are unsafe through the nearness of the dream possibility. The latter dreaming response to the safety objection to Sosa’s virtue epistemology has largely flown under the radar in contemporary discussions of safety and knowledge. We think that, suitably articulated in view of research in the philosophy and science of dreaming, it has much more going for it than has been appreciated. This paper further develops, beyond what Sosa does himself, the dreaming argument in response to those who think safety (as traditionally understood) is a condition on knowledge and who object to Sosa’s account on the grounds that it fails this condition. The payoffs of further developing this argument will be not only a better understanding of the importance of insights about dreaming against safety as a condition on knowledge, but also some reason to think a weaker safety condition, one that is relativised to SSS (i.e., skill/shape/situation) conditions for competence exercise, gets better results all things considered as an anti-luck codicil on knowledge. (shrink)

Epistemic Perceptualists claim that emotions are sources of immediate defeasible justification for evaluative propositions that can sometimes ground undefeated immediately justified evaluative beliefs. For example, fear can constitute the justificatory ground for a belief that some object or event is dangerous. Despite its attractiveness, the view is apparently vulnerable to several objections. In this paper, I provide a limited defence of Epistemic Perceptualism by responding to a family of objections which all take as a premise a popular and attractive view (...) in value theory – Neo-Sentimentalism – according to which values are analysed in terms of fitting emotions. (shrink)

The terms complexity, complex adaptive systems, and sciences of complexity are found often in recent scientific literature, reflecting the remarkable growth in collaborative academic research focused on complexity from the origin and dynamics of organisms to the largest social and political organizations. One of the great challenges in this field of research is to discover which features are essential and shared by all of the seemingly disparate systems that are described as complex. Is there sufficient synthesis to suggest the possibility (...) of an overarching science of complexity? This report describes current views on this subject held by various eminent scholars associated with the Santa Fe Institute.The physical sciences have traditionally been concerned with “simple” systems whose dynamics can be described in mathematical terms with precision and certainty. In contrast, the biological and social sciences are inevitably concerned with self-organized or social “complex” systems whose detailed behaviors appear to be unpredictable. The two categories differ greatly in size and diversity, prompting the late mathematician Stanislaus Ulam to remark that research on complex systems might be compared to the study of non-elephants. Nevertheless, certain integrative themes have begun to emerge.Rising activity in this field of research runs completely counter to the trend toward increasing fragmentation and specialization in the sciences. It has stimulated a resurgence of interest in a broad synthesis involving mathematics, computational science, physics, chemistry, biology, neuroscience, and the social sciences. The growth of effort in this very extended field has been greatly stimulated by the development of new computational tools that are capable of dealing with vast, interrelated databases. Many of the participants in complexity research feel that it is now time to reintegrate the fragmented interests of much of the academic community. The reader is encouraged to consider whether such views are sparking a historic renaissance of scholarship or represent a passing scientific diversion. (shrink)

In the recent metaethical literature there has been significant interest in the prospects for what I am denoting ‘Perceptual Intuitionism’: the view that normal ethical agents can and do have non-inferential justification for first-order ethical beliefs by having ethical perceptual experiences, e.g., Cullison 2010, McBrayer 2010, Vayrynen 2008. If true, it promises to constitute an independent a posteriori intuitionist epistemology, providing an alternative to intuitionist accounts which posit a priori intuition and/or emotion as sources of non-inferentially justified ethical beliefs. As (...) it is formulated, it is plausible that a necessary con- dition for the view is the truth of Ethical Perception: normal ethical agents can and do have perceptual experiences as of the instantiation of ethical properties. In this paper a sophisticated and promising account of Ethical Perception is offered. Extant objections are shown to fail. However, it will be argued that it is far from obvious that the account of Perceptual Intuitionism which emerges constitutes an independent alternative to other intuitionist accounts. This is because we have reason to think that ethical perceptual experience may be epistemically dependent on other epistemic sources, e.g. a priori intuition or emotion. (shrink)

C.D. Broad’s Reflections stands out as one of the few serious examinations of Moral Sense Theory in twentieth century analytic philosophy. It also constitutes an excellent discussion of the interconnections that allegedly exist between questions concerning what Broad calls the ‘logical analysis’ of moral judgments and questions about their epistemology. In this paper I make three points concerning the interconnectedness of the analytical and epistemological elements of versions of Moral Sense Theory. First, I make a general point about Broad’s association (...) between the Naïve Realist Moral Sense Theory (an epistemological view) and Objectivist Moral Sense Theory (a ‘logical analysis’). Second, I raise doubts about one of Broad’s arguments that Trans-Subjectivist Moral Sense Theory (logical analysis) can account for the apparent synthetic necessity of general moral propositions (epistemological). Third, I briefly discuss a view about logical analysis that should be of interest to contemporary Moral Sense Theorists – Neo-Sentimentalism – and respond to an argument whose conclusion is that this analysis is incompatible with a particular kind of epistemological view. (shrink)

Epistemic Sentimentalism is the view that emotional experiences such as fear and guilt are a source of immediate justification for evaluative beliefs. For example, guilt can sometimes immediately justify a subject’s belief that they have done something wrong. In this paper I focus on a family of objections to Epistemic Sentimentalism that all take as a premise the claim that emotions possess a normative property that is apparently antithetical to it: epistemic reason-responsiveness, i.e., emotions have evidential bases and justifications can (...) be demanded of them. I respond to these objections whilst granting that emotions are reason-responsive. This is not only dialectically significant vis-à-vis the prospects for Epistemic Sentimentalism, but also supports a broader claim about the compatibility of a mental item’s being reason-responsive and its being a generative source of epistemic justification. (shrink)

In recent years there has been renewed philosophical interest in the thesis that perceptual experience is cognitively penetrable, i.e., roughly, the view that the contents and/or character of a subject's perceptual experience can be modified by what a subject believes and desires. As has been widely noted, it is plausible that cognitive penetration has implications for perception's epistemic role. On the one hand, penetration could make agents insensitive to the world in a way which epistemically 'downgrades' their experience. On the (...) other hand, cognitive penetration may sometimes be epistemically beneficial by making agents more sensitive to the way the world is, i.e., by enabling them to see things that others cannot. For example, penetration could ground a 'high-level' view of perceptual content, according to which agents can have experiences as of 'complex' properties, e.g., natural kind and aesthetic properties. Relatedly, it could elucidate the view that agents can gain perceptual expertise by learning. A type of sophisticated perception which has hitherto received little attention in relation to cognitive penetration is ethical perception. In this paper I examine the significance of cognitive penetration for 'Perceptualist' views in ethics which appeal to a notion of 'ethical perception'. Although cognitive penetration could ground a literalist model of Ethical Perception according to which agents can have perceptual experiences of the instantiation of ethical properties, the results are otherwise somewhat mixed: cognitive penetrability does not support Perceptual Intuitionism, although it may provide some limited support for Virtue Ethics and Cornell Realism. However, as I stress, the significance of cognitive penetration for Perceptualism should not be overstated. (shrink)

Ce texte a déjà paru dans la revue October, N° 131, Winter 2010, p. 23–50. Nous remercions Michael Cowan de nous avoir autorisé à le reproduire ici. In September of 1925, readers leafing through Der Kinematograph or Lichtbildbühne or another such film journal might have encountered a strangely familiar sight : in an advertisement for a major exhibition of the German film and photography industries entitled “Kipho” (“Kino und Photo”), which was to be held in Berlin from September 25th (...) to (...) - Cinéma, animation et vidéo – GALERIE – Nouvel article. (shrink)

Ibn al-ʻArabī, 1165-1240; views on freedom; Sufism; Islamic philosophy.