We show that if T is a trivial uncountably categorical theory of Morley Rank 1 then T is model complete after naming constants for a model.

Long noncoding RNAs have been described in cell lines and various whole tissues, but lncRNA analysis of development in vivo is limited. Here, we comprehensively analyze lncRNA expression for the adult mouse subventricular zone neural stem cell lineage. We utilize complementary genome-wide techniques including RNA-seq, RNA CaptureSeq, and ChIP-seq to associate specific lncRNAs with neural cell types, developmental processes, and human disease states. By integrating data from chromatin state maps, custom microarrays, and FACS purification of the subventricular zone lineage, we (...) stringently identify lncRNAs with potential roles in adult neurogenesis. shRNA-mediated knockdown of two such lncRNAs, Six3os and Dlx1as, indicate roles for lncRNAs in the glial-neuronal lineage specification of multipotent adult stem cells. Our data and workflow thus provide a uniquely coherent in vivo lncRNA analysis and form the foundation of a user-friendly online resource for the study of lncRNAs in development and disease. © 2013 Elsevier Inc. (shrink)

This study investigated the relationship between concussions and medication adherence among 247 adults experiencing homelessness in Oklahoma City, Oklahoma, who were prescribed medication for a psychiatric disorder. Participants were asked whether they had “ever experienced a blow to the head that caused a concussion,” and medication adherence was measured by asking participants whether they had taken their psychiatric medication yesterday. The data were analyzed using univariate and multivariable logistic regressions. Results showed that more than half of the sample had a (...) concussion history, and homeless adults with a concussion history had higher odds of non-adherence to psychiatric medications compared with those who reported no concussion history [OR = 2.13 ]. Findings suggest that medication non-adherence is associated with incurred concussions. Raising awareness among service providers of the relationship between traumatic brain injury and medication adherence may increase efforts to improve adherence in this underserved population. (shrink)

One of this century’s most important philosophers here focuses on Plato’s Protagoras, Phaedo, Republic, and Philebus and on Aristotle’s three moral treatises to show the essential continuity of Platonic and Aristotelian reflection on the nature of the good.“Well translated and usefully annotated by P. Christopher Smith.... Gadamer’s book exhibits a broad and grand vision as well as a great love for the Greek thinkers.”-Alexander Nehemas, New York Times Book Review“The translation is highly readable. The translator’s introduction and frequent annotation provide (...) special elucidation on points of doctrinal complexity, giving ample references to other works and rival interpretations.”-Choice“This book is an important addition to the steadily growing number of Gadamer’s works available in English. In it, we see Gadamer at his best, that is, engaged in the practice of interpreting important texts from the philosophical tradition, and also at his most controversial.... I enthusiastically recommend this...challenging book as one that rewards all efforts to understand the important claims it makes on its readers.”-Francis J. Ambrosio, International Philosophy QuarterlyHans-Georg Gadamer is professor of philosophy emeritus at the University of Heidelberg. He is the author of numerous books, including two others translated by Smith: Dialogue and Dialectic: Eight Hermeneutical Studies on Plato and Hegel’s Dialectic: Five Hermeneutical Studies. (shrink)

The posterior cortex, hippocampus, and prefrontal cortex in the Leabra architecture are specialized in terms of various neural parameters, and thus are predilections for learning and processing, but domain-general in terms of cognitive functions such as face recognition. Also, these areas are not encapsulated and violate Fodorian criteria for modularity. Anderson's terminology obscures these important points, but we applaud his overall message.

Ecological developmental biology (eco‐devo) explores the mechanistic relationships between the processes of individual development and environmental factors. Recent studies imply that some of these relationships have deep evolutionary origins, and may even pre‐date the divergences of the simplest extant animals, including cnidarians and sponges. Development of these early diverging metazoans is often sensitive to environmental factors, and these interactions occur in the context of conserved signaling pathways and mechanisms of tissue homeostasis whose detailed molecular logic remain elusive. Efficient methods for (...) transgenesis in cnidarians together with the ease of experimental manipulation in cnidarians and sponges make them ideal models for understanding causal relationships between environmental factors and developmental mechanisms. Here, we identify major questions at the interface between animal evolution and development and outline a road map for research aimed at identifying the mechanisms that link environmental factors to developmental mechanisms in early diverging metazoans.Also watch the Video Abstract. (shrink)

Despite organizational ethical training programs, some employees still engage in unethical behavior. As such, organizational researchers have sought to examine why employees engage in unethical behavior and whether interventions can improve ethical misconduct. While some instruments measure moral development or ethical/unethical behaviors toward the organization, this study utilized a unique scale which evaluates perceptions of ethical misconduct (PEMS). Data from a large Midwestern university, a large Southeastern university, and Amazon’s Mechanical Turk were used in the analyses. An exploratory and confirmatory (...) factor analyses were used in the creation of the PEMS. To examine the validity of the scale, the PEMS was correlated to scales which measure Dark Triad traits and Counterproductive Work Behaviors (CWBs). Findings showed a significant positive correlation between the PEMS and both scales. The results also show that the PEMS mediates the relationship between psychopathy and CWBs. (shrink)

The traditional emphasis on the physics of the very small is questioned, and the suggestion made that a crucial test of contributions to the philosophy of science ought to be their applicability to areas which are more representative of the scientific enterprise. Life science is cited as just such an area. It is quantum physics, rather than biology, which nurtures anti-realism. The most respected anti-realism today is that provided by Bas C van Fraassen; and the persuasiveness of his "Constructive Empiricism" (...) is attested to by the failure of avowed realists, such as Ian Hacking, to distance themselves very far from van Fraassen's ideas. A detailed critique of van Fraassen is presented with particular attention paid to his ideas on scientific explanation - the question of whether good explanations are true explanations being one which tends to divide realist and anti-realist. The conclusion is reached that, while realism raises - and fails to answer - a number of philosophical questions, the anti-realism provided by Bas van Fraassen is no better at answering those questions. Moreover, it is argued, van Fraassen's ideas lack plausibility as a description of science and the attitudes of scientists - particularly when attention is shifted from physics to biology. Finally, a number of suggestions are made as to how the philosophical questions posed by realism might be answered in the future. (shrink)

This book assesses how Vatican II opened up the Catholic Church to encounter, dialogue, and engagement with other world religions. Opening with a contribution from the President of the Pontifical Council for Interreligious Dialogue, Cardinal Jean-Louis Tauran, it next explores the impact, relevance, and promise of the Declaration Nostra Aetate before turning to consider how Vatican II in general has influenced interfaith dialogue and the intellectual and comparative study of world religions in the postconciliar decades, as well as the contribution (...) of particular past and present thinkers to the formation of current interreligious and comparative theological methods. Additionally, chapters consider interreligious dialogue vis-à-vis theological anthropology in conciliar documents; openness to the spiritual practices of other faith traditions as a way of encouraging positive interreligious encounter; the role of lay and new ecclesial movements in interreligious dialogue; and the development of Monastic Interreligious Dialogue. Finally, it includes a range of perspectives on the fruits and future of Vatican’s II’s opening to particular faiths such as Judaism, Islam, Hinduism, and Buddhism. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

This handbook presents a comprehensive introduction to the core areas of philosophy of education combined with an up-to-date selection of the central themes. It includes 95 newly commissioned articles that focus on and advance key arguments; each essay incorporates essential background material serving to clarify the history and logic of the relevant topic, examining the status quo of the discipline with respect to the topic, and discussing the possible futures of the field. The book provides a state-of-the-art overview of philosophy (...) of education, covering a range of topics: Voices from the present and the past deals with 36 major figures that philosophers of education rely on; Schools of thought addresses 14 stances including Eastern, Indigenous, and African philosophies of education as well as religiously inspired philosophies of education such as Jewish and Islamic; Revisiting enduring educational debates scrutinizes 25 issues heavily debated in the past and the present, for example care and justice, democracy, and the curriculum; New areas and developments addresses 17 emerging issues that have garnered considerable attention like neuroscience, videogames, and radicalization. The collection is relevant for lecturers teaching undergraduate and graduate courses in philosophy of education as well as for colleagues in teacher training. Moreover, it helps junior researchers in philosophy of education to situate the problems they are addressing within the wider field of philosophy of education and offers a valuable update for experienced scholars dealing with issues in the sub-discipline. Combined with different conceptions of the purpose of philosophy, it discusses various aspects, using diverse perspectives to do so. Contributing Editors: Section 1: Voices from the Present and the Past: Nuraan Davids Section 2: Schools of Thought: Christiane Thompson and Joris Vlieghe Section 3: Revisiting Enduring Debates: Ann Chinnery, Naomi Hodgson, and Viktor Johansson Section 4: New Areas and Developments: Kai Horsthemke, Dirk Willem Postma, and Claudia Ruitenberg. (shrink)

Human moral judgement may have evolved to maximize the individual's welfare given parochial culturally constructed moral systems. If so, then moral condemnation should be more severe when transgressions are recent and local, and should be sensitive to the pronouncements of authority figures (who are often arbiters of moral norms), as the fitness pay-offs of moral disapproval will primarily derive from the ramifications of condemning actions that occur within the immediate social arena. Correspondingly, moral transgressions should be viewed as less objectionable (...) if they occur in other places or times, or if local authorities deem them acceptable. These predictions contrast markedly with those derived from prevailing non-evolutionary perspectives on moral judgement. Both classes of theories predict purportedly species-typical patterns, yet to our knowledge, no study to date has investigated moral judgement across a diverse set of societies, including a range of small-scale communities that differ substantially from large highly urbanized nations. We tested these predictions in five small-scale societies and two large-scale societies, finding substantial evidence of moral parochialism and contextual contingency in adults' moral judgements. Results reveal an overarching pattern in which moral condemnation reflects a concern with immediate local considerations, a pattern consistent with a variety of evolutionary accounts of moral judgement. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

The sense of touch informs us of the physical properties of our surroundings and is a critical aspect of communication. Before touches are perceived, mechanical signals are transmitted quickly and reliably from the skin's surface to mechano‐electrical transduction channels embedded within specialized sensory neurons. We are just beginning to understand how soft tissues participate in force transmission and how they are deformed. Here, we review empirical and theoretical studies of single molecules and molecular ensembles thought to be involved in mechanotransmission (...) and apply the concepts emerging from this work to the sense of touch. We focus on the nematode Caenorhabditis elegans as a well‐studied model for touch sensation in which mechanics can be studied on the molecular, cellular, and systems level. Finally, we conclude that force transmission is an emergent property of macromolecular cellular structures that mutually stabilize one another. (shrink)

Research on escalation of commitment has predominantly been studied in the context of a single decision without consideration for the psychological consequences of escalating. This study sought to examine a) the extent to which people escalate their commitment to a failing course of action in a sequential decision-making task, b) confidence and anger as psychological consequences of escalation of commitment, and c) the reciprocal relationship between escalation of commitment and confidence and anger. Participants were 110 undergraduate students who completed a (...) series of investment decisions regarding a failing endeavor. Results revealed that although a high proportion of individuals escalate through all decisions, the extent to which they escalated decreased with each decision as they were less willing to invest money in the project. Furthermore, as participants escalated, confidence in one’s decision decreased and anger increased. Lastly, the analyses revealed that the relationship between escalation and confidence is reciprocal. Escalation was negatively associated with confidence, and confidence predicted escalation in the subsequent decision. These results highlight the importance of considering both the determinants and psychological consequences of escalation of commitment. (shrink)

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

This volume contains essays by some of the leading scholars in the study of the Jewish religious ideas in the Second Temple period, that led up to the development of early forms of Rabbinic Judaism and Christianity. Close attention is paid to the cosmological ideas to be found in the Ancient Near East and in the Hebrew Bible and to the manner in which the translators of the Hebrew Bible into Greek reflected the creativity with which Judaism engaged Hellenistic ideas (...) about the cosmos and the creation. The concepts of heaven and divine power, human mortality, the forces of nature, combat myths, and the philosophy of wisdom, as they occur in 2 Maccabees, Ben Sira, Wisdom of Solomon and Tobit, are carefully analysed and compared with Greek and Roman world-views. There are also critical examinations of Dead Sea scroll texts, early Jewish prayers and Hebrew liturgical poetry and how they these adopt, adapt and alter earlier ideas. The editors have included appreciations of two major figures who played important roles in the study of the Second Temple period and in the history and development of the ISDCL, namely, Otto Kaiser and Alexander Di Lella, who died recently and are greatly missed by those in the field."--Provided by publisher. (shrink)

Lewis et al. (2011) attempted to restore the reputation of Samuel George Morton, a 19th century physician who reported on the skull sizes of different folk-races. Whereas Gould (1978) claimed that Morton's conclusions were invalid because they reflected unconscious bias, Lewis et al. alleged that Morton's findings were, in fact, supported, and Gould's analysis biased. We take strong exception to Lewis et al.’s thesis that Morton was “right.” We maintain that Gould was right to reject Morton's analysis as inappropriate and (...) misleading, but wrong to believe that a more appropriate analysis was available. Lewis et al. fail to recognize that there is, given the dataset available, no appropriate way to answer any of the plausibly interesting questions about the “populations” in question (which in many cases are not populations in any biologically meaningful sense). We challenge the premise shared by both Gould and Lewis et al. that Morton's confused data can be used to draw any meaningful conclusions. This, we argue, reveals the importance of properly focusing on the questions asked, rather than more narrowly on the data gathered. (shrink)

ABSTRACT. May scientists rely on substantive, a priori presuppositions? Quinean naturalists say "no," but Michael Friedman and others claim that such a view cannot be squared with the actual history of science. To make his case, Friedman offers Newton's universal law of gravitation and Einstein's theory of relativity as examples of admired theories that both employ presuppositions (usually of a mathematical nature), presuppositions that do not face empirical evidence directly. In fact, Friedman claims that the use of such presuppositions (...) is a hallmark of "science as we know it." But what should we say about the special sciences, which typically do not rely on the abstruse formalisms one finds in the exact sciences? I identify a type of a priori presupposition that plays an especially striking role in the development of empirical psychology. These are ontological presuppositions about the type of object a given science purports to study. I show how such presuppositions can be both a priori and rational by investigating their role in an early flap over psychology's contested status as a natural science. The flap focused on one of the field's earliest textbooks, William James's Principles of Psychology. The work was attacked precisely for its reliance on a priori presuppositions about what James had called the "mental state," psychology's (alleged) proper object. I argue that the specific presuppositions James packed into his definition of the "mental state" were not directly responsible to empirical evidence, and so in that sense were a priori; but the presuppositions were rational in that they were crafted to help overcome philosophical objections (championed by neo-Hegelians) to the very idea that there can be a genuine science of mind. Thus, my case study gives an example of substantive, a priori presuppositions being put to use—to rational use—in the special sciences. In addition to evaluating James's use of presuppositions, my paper also offers historical reflections on two different strands of pragmatist philosophy of science. One strand, tracing back through Quine to C. S. Peirce, is more naturalistic, eschewing the use of a priori elements in science. The other strand, tracing back through Kuhn and C. I. Lewis to James, is more friendly to such presuppositions, and to that extent bears affinity with the positivist tradition Friedman occupies. (shrink)

Spiel und Arbeit gelten oft als Gegensätze: Das Spiel als freie Betätigung menschlicher Vermögen, die Arbeit als deren Subordination unter einen äußeren Zweck. Die Festlegung des Spiels auf konsequenzlose Wiederholbarkeit hat ihm den Ruf des Unernsten eingetragen, während das Abzwecken der Arbeit auf die Nützlichkeit ihres Resultats im Bund mit der Sorge ums Dasein steht. Auf einen zweiten Blick scheint dieser Gegensatz jedoch, gerade in den hochentwickeltsten Ausprägungen beider Tätigkeitsformen, zu verschwinden. So kann eine hochgradige Rationalisierung von Spielpraktiken in Arbeit (...) umschlagen, wie etwa im Leistungssport, oder ein komplexer Arbeitsvorgang selbstzweckhafte Momente und Eigendynamiken gewinnen, die ihm Spielcharakter verleihen. Auch andere technologische Entwicklungen geben Anlass dazu, das Verhältnis von Spiel und Arbeit noch einmal grundsätzlich zu bedenken, etwa im Hinblick auf: adaptive Systeme in der Robotik, serious games, Kreativitätstechniken in Unternehmenskulturen, wissenschaftliche Experimentalanordnungen, Online-Rollenspiele oder die Kommodifizierung nicht-zweckrationaler Lebensvollzüge, die traditionell vom Begriff produktiver Arbeit ausgeschlossen waren – einschließlich der Spielräume, die durch neue Umwelt- und Biotechniken erschlossen werden. Die Beschaffenheit der jeweils zum Einsatz kommenden Mittel und Verfahren sowie die Setzung, Variation oder Preisgabe von Zwecken können den Charakter von Spiel und Arbeit sowie ihr Verhältnis zueinander bestimmen oder verändern. Mit Beiträgen von Francesco Amigoni, Andreas Brenneis, Petra Gehring, Armin Grunwald, Florian Heßdörfer, Wolfram Ette, Christoph Hubig, Andreas Kaminski, Nicole C. Karafyllis, Christian Klager, Alexander Kluge, Uwe Küster, Oliver Laas, Hildrun Lampe, Pieter Lemmens, Stefan Meißner, Alfred Nordmann, Felix Raczkowski, Markus Rautzenberg, Michael Resch, Nicole J. Saam, Viola Schiaffonati, Alexander Schmidl, Jan C. Schmidt und G. Günter Voß. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 35.1 (2002) 77-89 [Access article in PDF] Time and Judgment in Demosthenes' De Corona 1 - [PDF] Michael S. Kochin Hannah Arendt concludes the first volume of The Life of the Mind thus: If judgment is our faculty for dealing with the past, the historian is the inquiring man who by relating it sits in judgment over it. If that is so, we may reclaim (...) our human dignity, win it back, as it were, from that pseudo-divinity named History of the modern age, without denying history's importance but denying its right to being the ultimate judge. Old Cato... has left us a curious phrase which aptly sums up the political principle implied in the enterprise of reclamation. He said: "Victrix causa deis placit, sed victa Catoni" ("The victorious cause pleased the gods, but the defeated one pleases Cato"). (1978, 1: 216) 2This article is an exercise in reclamation of the kind that Hannah Arendt describes. I wish to reclaim the cause for which Demosthenes struggled, the cause of democratic freedom, from the judgment of history expressed in the defeat of Athens and her allies at the hands of Philip of Macedon. Though politics is attenuated in the contemporary world, we can understand the peculiar characteristics of political action by reconstructing in our imagination those moments in the past when political life was richest. Here I am going to take up an aspect of political action that is particularly well-illuminated in Demosthenes' speech On the Crown: the role of time in the judgment of political action. 3We can approach Demosthenes' political career for a variety of purposes: The easiest to understand, because it is in many ways the most superficial, is with the motives of the humanist. We study the political speeches of Demosthenes in order to be inspired to value political freedom [End Page 77] and to learn how it can be defended. The trouble with this view is that it assumes that the conditions for political action are present for us, as they were for Demosthenes in the Athens of his time, and that political action is itself something serious men (and now women) ought to undertake. That these two assumptions are edifying and patriotic does not make them true.We can also approach Demosthenes as an exercise in historical science (that is, historische Wissenschaft). The scientific historian wants to learn the facts about the rise of Philip's hegemony over Greece. The scientific historian therefore prefers objectivity to edification. As George Cawkwell, a leading participant in the Demosthenesstreit in the '60s and '70s, wrote, "Moral edification and history can be kept separate" (1969, 166).I find this the most difficult purpose to understand, because it is unclear how this scientific-historical perspective can be connected with the human-all-too-human perspectives of the participants. When, for example, Cawkwell writes of the age of Demosthenes that "The central fact of the age is military, not moral—viz. the huge preponderance in military potential of the Macedonian state over the power of any Greek state," he cites a fact whose truth he himself perceives in part from Philip's victory over the Thebans and Athenians at Chaeroneia in 338 B.C.E. and Alexander's campaign against Thebes in 335. 4 Cawkwell does not trouble himself to explain how Demosthenes or anybody else could possibly have learned the fact of Philip's greater military strength and resources prior to these events. Nor does Cawkwell refute the claim that given Philip's failures before Perinthos and Byzantium in 340, at the very time that Demosthenes led the Athenians to war it was reasonable to suppose Philip much weaker than he had seemed, or seems to us (Pickard-Cambridge 1979, 491). 5 He does not even show how Philip could have known his own capabilities prior to his success. It is thus unclear what use historical-scientific judgment could be, since it is not clear how to relate historical-scientific judgment to the judgment of participants in human affairs.I should stop here, not least because I... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 35.1 (2002) 77-89 [Access article in PDF] Time and Judgment in Demosthenes' De Corona 1 - [PDF] Michael S. Kochin Hannah Arendt concludes the first volume of The Life of the Mind thus: If judgment is our faculty for dealing with the past, the historian is the inquiring man who by relating it sits in judgment over it. If that is so, we may reclaim (...) our human dignity, win it back, as it were, from that pseudo-divinity named History of the modern age, without denying history's importance but denying its right to being the ultimate judge. Old Cato... has left us a curious phrase which aptly sums up the political principle implied in the enterprise of reclamation. He said: "Victrix causa deis placit, sed victa Catoni" ("The victorious cause pleased the gods, but the defeated one pleases Cato"). (1978, 1: 216) 2This article is an exercise in reclamation of the kind that Hannah Arendt describes. I wish to reclaim the cause for which Demosthenes struggled, the cause of democratic freedom, from the judgment of history expressed in the defeat of Athens and her allies at the hands of Philip of Macedon. Though politics is attenuated in the contemporary world, we can understand the peculiar characteristics of political action by reconstructing in our imagination those moments in the past when political life was richest. Here I am going to take up an aspect of political action that is particularly well-illuminated in Demosthenes' speech On the Crown: the role of time in the judgment of political action. 3We can approach Demosthenes' political career for a variety of purposes: The easiest to understand, because it is in many ways the most superficial, is with the motives of the humanist. We study the political speeches of Demosthenes in order to be inspired to value political freedom [End Page 77] and to learn how it can be defended. The trouble with this view is that it assumes that the conditions for political action are present for us, as they were for Demosthenes in the Athens of his time, and that political action is itself something serious men (and now women) ought to undertake. That these two assumptions are edifying and patriotic does not make them true.We can also approach Demosthenes as an exercise in historical science (that is, historische Wissenschaft). The scientific historian wants to learn the facts about the rise of Philip's hegemony over Greece. The scientific historian therefore prefers objectivity to edification. As George Cawkwell, a leading participant in the Demosthenesstreit in the '60s and '70s, wrote, "Moral edification and history can be kept separate" (1969, 166).I find this the most difficult purpose to understand, because it is unclear how this scientific-historical perspective can be connected with the human-all-too-human perspectives of the participants. When, for example, Cawkwell writes of the age of Demosthenes that "The central fact of the age is military, not moral—viz. the huge preponderance in military potential of the Macedonian state over the power of any Greek state," he cites a fact whose truth he himself perceives in part from Philip's victory over the Thebans and Athenians at Chaeroneia in 338 B.C.E. and Alexander's campaign against Thebes in 335. 4 Cawkwell does not trouble himself to explain how Demosthenes or anybody else could possibly have learned the fact of Philip's greater military strength and resources prior to these events. Nor does Cawkwell refute the claim that given Philip's failures before Perinthos and Byzantium in 340, at the very time that Demosthenes led the Athenians to war it was reasonable to suppose Philip much weaker than he had seemed, or seems to us (Pickard-Cambridge 1979, 491). 5 He does not even show how Philip could have known his own capabilities prior to his success. It is thus unclear what use historical-scientific judgment could be, since it is not clear how to relate historical-scientific judgment to the judgment of participants in human affairs.I should stop here, not least because I... (shrink)

"Neofunctionalism and After" brings together for the first time in one volume all of Alexander's writings on neofunctionalism, the present volume also contains ...

Abstract: In this article, I offer a proposal to clarify what I believe is the proper relation between value maximization and stakeholder theory, which I call enlightened value maximization. Enlightened value maximization utilizes much of the structure of stakeholder theory but accepts maximization of the long-run value of the firm as the criterion for making the requisite tradeoffs among its stakeholders, and specifies long-term value maximization or value seeking as the firm’s objective. This proposal therefore solves the problems that arise (...) from the multiple objectives that accompany traditional stakeholder theory. I also discuss the Balanced Scorecard, which is the managerial equivalent of stakeholder theory, explaining how this theory is flawed because it presents managers with a scorecard that gives no score—that is, no single-valued measure of how they have performed. Thus managers evaluated with such a system (which can easily have two dozen measures and provides no information on the tradeoffs between them) have no way to make principled or purposeful decisions. The solution is to define a true (single dimensional) score for measuring performance for the organization or division (and it must be consistent with the organization’s strategy), and as long as their score is defined properly, (and for lower levels in the organization it will generally not be value) this will enhance their contribution to the firm. (shrink)

The arguments for redistribution of wealth, and for prohibiting certain transactions such as price-gouging, both are based in mistaken conceptions of exchange. This paper proposes a neologism, “euvoluntary” exchange, meaning both that the exchange is truly voluntary and that it benefits both parties to the transaction. The argument has two parts: First, all euvoluntary exchanges should be permitted, and there is no justification for redistribution of wealth if disparities result only from euvoluntary exchanges. Second, even exchanges that are not euvoluntary (...) should generally be permitted, because access to market exchange may be the only means by which people in desperate circumstances can improve their position. (shrink)

What methodology should philosophers follow? Should they rely on methods that can be conducted from the armchair? Or should they leave the armchair and turn to the methods of the natural sciences, such as experiments in the laboratory? Or is this opposition itself a false one? Arguments about philosophical methodology are raging in the wake of a number of often conflicting currents, such as the growth of experimental philosophy, the resurgence of interest in metaphysical questions, and the use of formal (...) methods. This outstanding collection of specially-commissioned chapters by leading international philosophers discusses these questions and many more. It provides a comprehensive survey of philosophical methodology in the most important philosophical subjects: metaphysics, epistemology, philosophy of language, philosophy of mind, phenomenology, philosophy of science, ethics, and aesthetics. A key feature of the collection is that philosophers discuss and evaluate contrasting approaches in each subject, offering a superb overview of the variety of methodological approaches - both naturalistic and non-naturalistic - in each of these areas. They examine important topics at the heart of methodological argument, including the role of intuitions and conceptual analysis, thought experiments, introspection, and the place that results from the natural sciences should have in philosophical theorizing. The collection begins with a fascinating exchange about philosophical naturalism between Timothy Williamson and Alexander Rosenberg, and also includes contributions from the following philosophers: Lynne Rudder Baker, Matt Bedke, Greg Currie, Michael Devitt, Matthew C. Haug, Jenann Ismael, Hilary Kornblith, Neil Levy, E.J. Lowe, Kirk Ludwig, Marie McGinn, David Papineau, Matthew Ratcliffe, Georges Rey, Jeffrey W. Roland, Barry C. Smith, Amie L. Thomasson, Valerie Tiberius, Jessica Wilson, and David W. Smith. (shrink)

This paper defends Mereological Universalism(the thesis that, for any set S of disjoint objects, there is an object that the members of S compose. Universalism is unpalatable to many philosophers because it entails that if there are such things as my left tennis shoe, W. V. Quine, and the Taj Mahal, then there is another object that those three things compose. This paper presents and criticizes Peter van Inwagen's argument against Universalism and then presents a new argument in favor of (...) Universalism. It turns out that the most reasonable way to resist the argument for Universalism is to deny the existence of artifacts; thus, if we believe in artifacts, we have no real choice other than to embrace Universalism. (shrink)

This paper defends Mereological Universalism (the thesis that, for any set S of disjoint objects, there is an object that the members of S compose. Universalism is unpalatable to many philosophers because it entails that if there are such things as my left tennis shoe, W. V. Quine, and the Taj Mahal, then there is another object that those three things compose. This paper presents and criticizes Peter van Inwagen’s argument against Universalism and then presents a new argument in favor (...) of Universalism. It turns out that the most reasonable way to resist the argument for Universalism is to deny the existence of artifacts; thus, if we believe in artifacts, we have no real choice other than to embrace Universalism. (shrink)

There are five individually plausible and jointly incompatible assumptions underlying four familiar puzzles about material constitution. The problem of material constitution just is the fact that these five assumptions are both plausible and incompatible. I will begin by providing a very general statement of the problem. I will present the five assumptions and provide a short argument showing how they conflict with one another. Then, in subsequent sections, I will go on to show how these assumptions underlie each of the (...) four puzzles. I will conclude by providing an exhaustive taxonomy of possible solutions to the problem. (shrink)

The European Legacy, Volume 17, Issue 4, Page 568-569, July 2012.

In debate about the nature of persistence over time, the view that material objects endure has played the role of "champion" and the view that they perdure has played the role of the "challenger." It has fallen to the perdurantists rather than the endurantists to motivate their view, to provide reasons for accepting it that override whatever initial presumption there is against it. Perdurantists have sought to discharge their burden in several ways. For example, perdurantism has been recommend on the (...) grounds that: (i) it solves several of the puzzles that raise the problem of material constitution; (ii) it is (at least) suggested by the special theory of relativity (hereafter "SR"); (iii) it is the only view that makes sense out of the possibility of intrinsic change; (iv) it is the only view consistent with the doctrine of Humean supervenience; and (v) it makes better sense than its competitor out of the possibility of fission. There are primary and most powerful claims that have been made on behalf of perdurantism. They are individually persuasive and together they constitute a formidable assault upon the hegemony of endurantism. Endurantists of course, have not been without reply. However, since endurantists typically respond to these claims one at a time and in different ways, it is easy to get the impression that perdurantism offers a single, neat solution to a host of problems whereas endurantism requires a patchwork of different strategies. But this impression is an illusion. In Rea 1995, I argued that though perdurantism does solve some of the puzzles that raise the problem of material constitution, it does not solve the problem of material constitution itself. Thus, the problem of material constitution really has no bearing on the debate between endurantists and perdurantists. In his paper, I will show that the same is true with respect to SR, the problem of intrinsic change, the doctrine of Humean supervenience, and the possibility of fission. In short, I will argue that none of (ii-v) is true and that therefore the doctrine of temporal parts stands unmotivated. (shrink)

There are various puzzles that set our intuitions about composition and identity against one another. Four that are particularly well known are the Growing Argument, the Ship of Theseus Puzzle, the Body-minus Argument, and Allan Gibbard’s puzzle about Lumpl and Goliath. Such puzzles have received a great deal of attention in the literature over the past thirty years, and there is an impressive and growing variety of solutions available for each of them. Surprisingly, however, no one has really discussed how (...) all of the different puzzles, and their solutions, are interrelated. On the surface, they seem to raise different problems; but clearly the puzzles are related somehow. They raise similar questions and generate similar sets of possible solutions. But, as yet, nothing has been said about how far the similarities extend. (shrink)

In debate about the nature of persistence over time, the view that material objects endure has played the role of “champion” and the view that they perdure has played the role of “challenger.” As in other contests, the champion’s job is merely to defend her title, whereas the challenger’s job is to prove herself worthy. I have no view about how these roles came to be assigned; but the historical fact is that perdurantists have traditionally borne the proverbial burden of (...) proof in this debate. It has fallen to the perdurantists rather than the endurantists to motivate their view, to provide reasons for accepting it that override whatever initial presumption there is against it. (shrink)

Griffiths and Tenenbaum (2006) asked individuals to make predictions about the duration or extent of everyday events (e.g., cake baking times), and reported that predictions were optimal, employing Bayesian inference based on veridical prior distributions. Although the predictions conformed strikingly to statistics of the world, they reflect averages over many individuals. On the conjecture that the accuracy of the group response is chiefly a consequence of aggregating across individuals, we constructed simple, heuristic approximations to the Bayesian model premised on the (...) hypothesis that individuals have access merely to a sample of k instances drawn from the relevant distribution. The accuracy of the group response reported by Griffiths and Tenenbaum could be accounted for by supposing that individuals each utilize only two instances. Moreover, the variability of the group data is more consistent with this small‐sample hypothesis than with the hypothesis that people utilize veridical or nearly veridical representations of the underlying prior distributions. Our analyses lead to a qualitatively different view of how individuals reason from past experience than the view espoused by Griffiths and Tenenbaum. (shrink)

Social theory between progress and apocalypse -- Autonomy and domination: Weber's cage -- Barbarism and modernity: Eisenstadt's regret -- Integration and justice: Parsons' utopia -- Despising others: Simmel's stranger -- Meaning evil -- De-civilizing the civil sphere -- Psychotherapy as central institution -- The frictions of modernity and their possible repair.

The strong predominance of right-handedness appears to be a uniquely human characteristic, whereas the left-cerebral dominance for vocalization occurs in many species, including frogs, birds, and mammals. Right-handedness may have arisen because of an association between manual gestures and vocalization in the evolution of language. I argue that language evolved from manual gestures, gradually incorporating vocal elements. The transition may be traced through changes in the function of Broca's area. Its homologue in monkeys has nothing to do with vocal control, (...) but contains the so-called “mirror neurons,” the code for both the production of manual reaching movements and the perception of the same movements performed by others. This system is bilateral in monkeys, but predominantly left-hemispheric in humans, and in humans is involved with vocalization as well as manual actions. There is evidence that Broca's area is enlarged on the left side in Homo habilis, suggesting that a link between gesture and vocalization may go back at least two million years, although other evidence suggests that speech may not have become fully autonomous until Homo sapiens appeared some 170,000 years ago, or perhaps even later. The removal of manual gesture as a necessary component of language may explain the rapid advance of technology, allowing late migrations of Homo sapiens from Africa to replace all other hominids in other parts of the world, including the Neanderthals in Europe and Homo erectus in Asia. Nevertheless, the long association of vocalization with manual gesture left us a legacy of right-handedness. Key Words: cerebral dominance; gestures; handedness; hominids; language evolution; primates; speech; vocalization. (shrink)