Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Many word forms in natural language are polysemous, but only some of them allow for co-predication, that is, they allow for simultaneous predications selecting for two different meanings or senses of a nominal in a sentence. In this paper, we try to explain (i) why some groups of senses allow co-predication and others do not, and (ii) how we interpret co-predicative sentences. The paper focuses on those groups of senses that allow co-predication in an especially robust and stable way. We (...) argue, using these cases, but focusing particularly on the multiply polysemous word ‘school’, that the senses involved in co-predication form especially robust activation packages, which allow hearers and readers to access all the different senses in interpretation. (shrink)

Artificial intelligence (AI) is booming, and AI ethics is booming with it. Yet there is surprisingly little attention paid to what the discipline of AI ethics is and what it ought to be. This paper offers an ameliorative definition of AI ethics to fill this gap. We introduce and defend an original distinction between novel and applied research questions. A research question should count as AI ethics if and only if (i) it is novel or (ii) it is applied and (...) has gained new importance through the development of AI. We argue that a lack of such a definition contributes to six disciplinary problems: ethics washing and lobbying, limited applicability, dilution of the field, conceptual bloating, costs of AI ethics, and an internal dispute. Based on our definition, we construct a methodological framework for AI ethics and show how it helps address these problems. (shrink)

The aim of this paper is to explore the status of argumentative discourse. We argue that argumentation can contribute to instances of different discourse genres, regardless of whether it is functional to their purposes. By analyzing examples from the daily press in the light of an approach to discourse analysis inspired by pragmatics, we show that also texts that are not expected to be argumentative have underlying argumentative structures and that a text’s being argumentative is a matter of degree: the (...) understanding of underlying argumentative structures contributes to a varying extent to the understanding of what a text as a whole means and of its point in the speech situation. This role of argumentative structures in text understanding suggests considering argumentation as a cognitively-based dimension of discourse, connected to human rationality. (shrink)

Una cultura política orientada al entendimiento y la paz requiere, sostendré, no sólo que se tengan las disposiciones correctas, sino, ante todo, la convicción de que incluso nuestras disposiciones morales se encuentran enraizadas en la razón y la reflexión. Bajo este punto de vista, el cultivo de una cultura política respetuosa del otro y sensata supone que tanto la sociedad como sus instituciones ya han contribuido a un clima moral deliberativo, uno que no cree simplemente que la moral es sólo (...) el resultado de poseer la psicología o sensibilidad correctas, sino que sostiene que la moral debe ser promovida en la discusión pública y reflexiva. Por esta razón, en mi artículo examino y rechazo algunas fundamentaciones de la moral que separan demasiado tajantemente la razón del sentido moral. Examino la así llamada posición “internalista”, cuya figura más prominente fue Bernard Williams, y la confronto con una postura que admite una mayor participación de la deliberación racional en las decisiones morales, en particular en aquellas que conciernen la elección de principios de justicia. Sostengo que el internalismo moral sólo sirve a una teoría política que reduce la razón humana a la mera voluntad de poder. (shrink)

El presente artículo busca reflexionar sobre la convergencia de los conceptos “saber” y “sabor” en la gastronomía, desde las perspectivas antropológica (a partir del análisis cultural) y filosófica (a partir del análisis epistemológico). Este objetivo se sustenta en el postulado de la vigencia de la gastronomía como elemento, hecho y fenómeno cultural, como producto de valores simbólicos y funcionales que propician el desarrollo y el bienestar de los grupos humanos.

In all cultures, ethnomedical practices are largely the same for animals and people, whether in mode of administration of materia medica, in the materials themselves, or in surgical, mechanical, behavioral, medico-religious, and other realms. Below, parallels between veterinary and human ethnomedical techniques are outlined. Taken together, they suggest that a number of benefits could be gained by closer collaboration between veterinary and human medicine in the delivery of basic healthcare information and services.

The ability to sequence individual genomes is leading to the identification of an increasing number of genetic risk factors for serious diseases. Knowledge of these risk factors can often provide significant medical and psychological benefit, but also raises complex ethical and social issues. This paper focuses on one area of rapid progress: the identification of mutations causing long QT syndrome and other cardiac channel disorders, which can explain some previously unexplained deaths in infants (SIDS) and children and adults (SUDS) and (...) prevent others from occurring. This genetic knowledge, discovered posthumously in many cases, has implications for clinical care for surviving family members who might carry the same mutations. The information obtained from genetic testing, in the context of personal and family history, can guide individually tailored interventions that reduce risk and save lives. At the same time, obtaining and disclosing genetic information raises difficult issues about confidentiality and decision making within families. We draw on the experience of the Montefiore-Einstein Center for Cardiogenetics, which has played a leading role in the genetic diagnosis and clinical management of cardiac channel diseases, to explore some of the challenging ethical questions arising in affected families with adolescent children. We focus on the related issues of (1) family confidentiality, privacy and disclosure and (2) adolescent decision making about genetic risk, and argue for the value of interdisciplinary dialogue with affected families in resolving these issues. (shrink)

One of several important issues that inform contemporary philosophy of chemistry is the issue of structural explanation, precisely because modern chemistry is primarily concerned with microstructure. This paper argues that concern over microstructure, albeit understood differently than it is today, also informs the chemical philosophy of Robert Boyle. According to Boyle, the specific microstructure of ‘chymical atoms’, understood in geometric terms, accounts for the unique essential properties of different chemical substances. Because he considers the microstructure of ‘chymical atoms’ as semi-permanent, (...) Boyle considers these stable entities as operationally irreducible, even if they are not ontologically fundamental. While it is generally believed that our contemporary concern over structural explanation is a function of modern chemistry’s emphasis on microstructure, this discussion of structural explanation in Boyle will serve as a case study to illustrate the manner in which many of our contemporary concerns have deeply historical origins and the manner in which the history of chemistry can substantively inform issues in contemporary philosophy of chemistry. (shrink)

This essay proposes to discuss the manner in which Jan Baptista van Helmont helped to transform the Neoplatonic notions of vital spirit and of ferment by giving these notions an unambiguously chemical interpretation, thereby influencing the eventual naturalization of these ideas in the work of late seventeenth century chymists. This chemical interpretation of vital spirit and ferment forms part of Helmont’s hybrid ontology, which fuses a corpuscular conception of minima naturalia with a non-corporeal conception of semina rerum. For Helmont, chemical (...) alterations involve the minima as physical units but also depend upon ferments that are contained in the semina, which function as formative spiritual agents. Helmont’s nuanced ontology ultimately contributes to the development of modern corpuscularian theory by explaining many chemical reactions in fundamentally corpuscular terms, as the addition and subtraction of particles. (shrink)

The author deals with the nature of a relationship between art and morals. Since art refers to the expression of a sensibility and modern moral philosophy issaid to be based upon being in possession of a moral sense, it seems that theartistic personality would be in a better position than mere refle..

El trabajo somete a discusión algunos elementos y argumentos del ensayo Anti-Nietzsche. La crueldad de lo político de Jorge Polo Blanco. La obra es analizada desde la perspectiva del problema de la diversidad de caracterizaciones que obtiene la filosofía de Nietzsche en el pensamiento filosófico contemporáneo y el desafío que supone evaluar la filosofía de Nietzsche a la luz de nuestra sensibilidad democrática. Se examinan los capítulos de la obra apuntando algunas de las incorrecciones y aspectos más problemáticos de su (...) argumentario "anti-nietzscheano", incidiendo en la importancia del estudio de fuentes (Quellenforschung) y de la historia de las ediciones de la obra de Nietzsche. (shrink)

Este es un libro sobre la libertad y sobre la verdad. Y ahora ya podéis reír. Pero no os protejáis en la risa sarcástica, permitíos una risa impertinente. La libertad y la verdad son dos formas de impertinencia necesaria, cuando hemos comprendido que no somos realmente libres ni escaparemos nunca del error ni del engaño. De esto hablan estos textos, y lo hacen de la mano de diversos autores y personajes que han hecho de su impertinencia una forma de pensamiento. (...) Georg Büchner nos presenta a Danton y a Robespierre conversando ante la guillotina. Diderot y Sophie Volland escriben su amor en una eternidad sin Cielo. Joaquim Jordà filma a sus amigos mientras colectivizan la fábrica Numax y Teresa de Ávila corta cebollas en la cocina mientras charla con su inquisidor... El 'Torete' de Perros callejeros, Christa Leem, Ixiar Rozas o Santiago López Petit desafían la noche. Se añaden a ellos Albert Camus, conjurando la mentira, y los muertos de las comedias de Eduardo de Filippo, porque todo está lleno de muertos. Entre ellos y muchos más que recorren estas páginas, destaca la voz de mi abuela, Concepció Rubiés i Trias, quien vuelve directamente a nosotros a través de las cartas que escribió cuando tenía dieciocho años y se marchó al exilio. Todas estas voces organizan una cacofonía que es, para mí, una fiesta de la inteligencia, en un tiempo en el que se ha hecho muy difícil sentir la alegría de pensar. Las malas compañías no se escogen, pero se puede decidir seguirlas o no. A mí, siempre me han llevado por buen camino. (shrink)

This article reports the results of an investigation into the issues encountered by undergraduate language students while engaging in ‘the Grammar Project’ - a collaborative assessment task for the module Academic and Professional Skills for Language Learning - and shows how encouraging students to take ownership of their learning process with the support of a Virtual Learning Environment can increase their motivation and their understanding of the subject matter. It shows that students’ beliefs may hinder their learning experience, while maintaining (...) that an effective social-interactive environment can help them understand subject-specific concepts, particularly if this is supported by recording their reflections both within the VLE and in a portfolio. (shrink)

Содерж.: Грибная лихорадка ; Прости, пожалуйста, прости.

This article presents the results of the analysis of a number of linguistic metaphors found in a corpus of opinion articles published in the Spanish newspaper El País. The authors included in the corpus, who tend towards the left of the political spectrum, use metaphor to express moral judgements on the actions and decisions of the conservative, centre-right People’s party, which governs Spain with an overall majority. With the aim of describing this discourse, we have undertaken a qualitative analysis with (...) a conceptual framework deriving from CDA and cognitive linguistics. First, therefore, we have made use of the methodology developed by Steen and the Pragglejaz group to extract the discourse units that could be considered as the lexical expression of an underlying mapping between domains, that is, the metaphors; second, according to the descriptions of Talmy, Croft, Sweetser, Sullivan, and Dancygier and Sweetser, we have verified that the different types of grammatical structure in which the lexical items appeared also indicated the existence of a metaphorical thought process; and third, in the words of van Dijk, we have studied the ideological semantics underlying conceptual structures and conceptual content. As we have demonstrated, all the samples of linguistic metaphors found led readers to construct the same interpretation of the meaning: The Spanish People’s party government is the past, a past that provokes rejection and which was thought to be definitively ended. (shrink)

The article examines the conquest of the New World in the focus of interaction of different types of thinking in the clash and conflict of two civilizations, which develop in different ways and which are at different levels of social and economic development. The result of this clash was the destruction of the material, spiritual and intellectual traditions of indigenous cultures that existed on the American continent. The conquest of America is one of the most revealing examples of the clash (...) of civilizations, analyzing which, with particular clarity, one can observe contradictions between different types of world perception. The answer to questions about what kind of knowledge Nahua-speaking people possessed, what role knowledge played in their society, who was the creator, carrier and translator of knowledge about the world, reveals one of the main reasons that led to a rapid and irretrievable destruction of culture of “metaphors and numbers.” The author reveals the role of Catholic monks in preserving the spiritual, scientific and philosophical heritage of the Mexican culture, thanks to which we have the opportunity to touch the thought of the Nahua people, existing not in the form of traditional texts but in the form of an oral tradition, which accompanied visual images of graphic semantic writing. It shows how important the system of education and upbringing in the society of pre-Columbian Mexico was, how it solved the tasks of preparing young people for the performance of social functions. The destruction, as a result of the con- quest, of the system that regulated the daily life of each person and determined the ultimate destiny of the people in the shortest possible time led to the death of the entire civilization. (shrink)

This paper applies an Intersectionality Based Policy Analysis Framework to Ontario’s current mental health plan – The Roadmap: A Plan to Build Ontario’s Mental Health and Addictions Services – in order to identify the contextual influences, underlying values and assumptions, which promote or undermine the uptake of human rights and equity as a mental health policy priority in Ontario. We found that dominant framings of the “problem” of mental health (as lack of access, coordination or integration, as a fiscal drain, (...) as an economic burden, and as a clinical or medical problem) served to obscure and ignore the underlying social and structural conditions that impact mental health and the human rights violations that routinely occur in the context of “care.” We discuss the implications of The Roadmap ignoring social and structural determinants of health, and by way of contrast, explore how citizen engagement and activism can support rethinking mental health policy so that it is more just and equitable. (shrink)

El grano de ben es un fruto que ha sido utilizado con fines terapéuticos desde la Antigüedad. Su descripción está incluida en el libro VI del De simplicium medicamentorum facultatibus de Galeno (s. II), una de las obras farmacológicas más importantes de la historia de la medicina. En este artículo compararemos desde una perspectiva filológica la entrada que Galeno dedicó a este simple en dos de sus traducciones medievales: la árabe de Ḥunayn ibn Isḥāq (s. IX) y la latina de (...) Gerardo de Cremona (s. XII). Nuestro análisis ayudará a profundizar en el estudio de estas dos traducciones y en la técnica de Gerardo de Cremona, el traductor más prolífico de obras de medicina griega y árabe al latín en la Edad Media. (shrink)

The ‘1st Congress Churches and LGBTI+ Community: ecumenical dialogues for respect for diversity’ was held between 19th and 22nd of June 2019, in the city of São Paulo. The Congress was organised by the Parish of the Holy Trinity of the Episcopal Anglican Church in Brazil and Koinonia–Ecumenical Presence in Service. As we consider this congress a historic landmark in the debates concerning religions and sexualities that escape from cisheteronormativity in Brazil, in the course of this article, we propose to (...) analyse the social and political conjuncture that motivated the event. In a second step, we will briefly describe the structure of the event, as well as its objectives, in order to understand the assumptions that guided the construction of the Letter of São Paulo, the official and public document of the Congress, approved in plenary by the participants. We believe that the Congress and the Letter of São Paulo have political potential, as they claim the rights of lesbian, gay, bisexual, transgender, intersex+ people as people of faith and denounce forms of oppression, exclusion and marginalisation reinforced by conservative and hegemonic religious discourses. (shrink)