Results for 'minimal gene set'

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  1.  92
    What Does Nozick's Minimal State Do?Gene E. Mumy - 1987 - Economics and Philosophy 3 (2):275-305.
    In the first half of the 1970s, two books appeared which have subsequently been regarded as major works in political philosophy: John Rawls's A Theory of Justice, and Robert Nozick's Anarchy, State, and Utopia. Economists have devoted a considerable amount of ink to commentary, pro and con, on A Theory of Justice; and it is getting to be a rare public finance textbook that does not, in its discussion of governmental redistribution, describe the Kantian contract made behind the veil of (...)
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  2.  41
    Synthetic biology as a technoscience: The case of minimal genomes and essential genes.Massimiliano Simons - 2021 - Studies in History and Philosophy of Science Part A 85:127-136.
    This article examines how minimal genome research mobilizes philosophical concepts such as minimality and essentiality. Following a historical approach the article aims to uncover what function this terminology plays and which problems are raised by them. Specifically, four historical moments are examined, linked to the work of Harold J. Morowitz, Mitsuhiro Itaya, Eugene Koonin and Arcady Mushegian, and J. Craig Venter. What this survey shows is a historical shift away from historical questions about life or descriptive questions about specific (...)
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  3.  7
    Oakeshott on Rome and America.Gene Callahan - 2012 - Imprint Academic.
    The political systems of the Roman Republic were based almost entirely on tradition, “the way of the ancestors”, rather than on a written constitution. While the founders of the American Republic looked to ancient Rome as a primary model for their enterprise, nevertheless, in line with the rationalist spirit of their age, the American founders attempted to create a rational set of rules that would guide the conduct of American politics, namely, the US Constitution.These two examples offer a striking case (...)
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  4.  30
    History is Not Historicism.Gene Callahan - 2009 - Critical Review: A Journal of Politics and Society 21 (4):467-474.
    ABSTRACT Nassim Taleb’s dismissal of history as based on the “narrative fallacy”—which reads our present knowledge of past events into our reconstruction of the past—is based on a fundamental misconception of what historians actually do. Historians do not, as Taleb presumes, try to infer general, predictive laws from “hard” facts, as do natural scientists; instead their aim is to discover the causes of unique historical facts among antecedent facts. This is no different, in principle, from “narrating” the cause of a (...)
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  5.  17
    History is Not Historicism.Gene Callahan - 2009 - Critical Review: A Journal of Politics and Society 21 (4):467-474.
    ABSTRACT Nassim Taleb’s dismissal of history as based on the “narrative fallacy”—which reads our present knowledge of past events into our reconstruction of the past—is based on a fundamental misconception of what historians actually do. Historians do not, as Taleb presumes, try to infer general, predictive laws from “hard” facts, as do natural scientists; instead their aim is to discover the causes of unique historical facts among antecedent facts. This is no different, in principle, from “narrating” the cause of a (...)
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  6.  54
    Adorno, Brecht and Debord: Three Models for Resisting the Capitalist Art System.Gene Ray - 2013 - Nordic Journal of Aesthetics 23 (44-45).
    The article presents three models of radical cultural practice: Adorno’s dissonant modernism, Brecht’s “functional transformation” or “re-functioning” of institutions through estrangement and dialectical realism, and Debord’s Situationist détournement of art, aiming to rupture and decolonize naturalized everyday life. The three models all begin with a critical appropriation of the traditions of art and aims at resisting the social power that passes through art, as an institutionalized field of production and activity. Each of the three modes establishes a set of productive (...)
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  7. The Writ against Religious Drama: Frater Taciturnus v. Søren Kierkegaard.Gene Fendt - 1997 - In Niels J. Cappelørn (ed.), Kierkegaard Revisited: Proceedings From the Conference. Berlin, Germany: de Gruyter. pp. 48-74.
    In a very literarily complicated setting, Frater Taciturnus sets a remark about Hamlet not being a Christian tragedy. After unpeeling that literary setting and noting that Taciturnus' remark aims more at Jacob Börne than at Shakespeare, the paper shows how Frater Taciturnus' remark calls into question the religious project of a certain danish author. For, Taciturnus' primary concern is to show that religious drama is not possible, or at least "ought not be." This general law applies to Hamlet as well, (...)
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  8.  3
    The Engineering Project: Its Nature, Ethics, and Promise.Gene Moriarty - 2015 - Pennsylvania State University Press.
    We all live our daily lives surrounded by the products of technology that make what we do simpler, faster, and more efficient. These are benefits we often just take for granted. But at the same time, as these products disburden us of unwanted tasks that consumed much time and effort in earlier eras, many of them also leave us more disengaged from our natural and even human surroundings. It is the task of what Gene Moriarty calls focal engineering to (...)
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  9.  66
    Confessions_’Bliss: Postmodern Criticism as a Palimpsest of Augustine's _Confessions.Gene Fendt - 1995 - Heythrop Journal 36 (1):30-45.
    This paper reads through some contemporary literary critical problems and theorizing about textuality to Augustine's Confessions, to the enrichment, if not the ecstasy of both contemporary and medieval thinking. It shows that Augustine is both aware of much that passes as new in theorizing about language, and that his text is argumentatively and rhetorically structured to set difference at play. Like Augustine's writing, this article is a performance piece: besides arguing, it acknowledges; beside demonstration, it questions; besides telling, it shows; (...)
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  10.  23
    Love Song for the Life of the Mind: An essay on the purpose of comedy.Gene Fendt - 2007 - Washington, DC, USA: Catholic University of America Press.
    Prefaced by an argument that the ancients understood mimesis as fundamental to being human, and art as therefore essential to human moral and intellectual development, this book starts from the problematic status of the (happily ending) Iphigenia in Poetics. How Aristotle must explicate tragedy to hold Iphigenia as the best thus sets up the exploration of comedy. Chapter two shows that comedy aims at the catharsis of desire and sympathy. This analysis is then applied in detail to Aristophanes’ Acharnians, Shakespeare’s (...)
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  11. The Anatomy of Truth: Literary Modes as a Kantian Model for Understanding the Openness of Knowledge and Morality to Faith.Gene Fendt - 2006 - In Chris L. Firestone & Stephen R. Palmquist (eds.), Kant and the New Philosophy of Religion. Bloomington, IN, USA: Indiana University Press. pp. 90-104.
    Kant's famous statement (from the first Critique) that he found it necessary to deny knowledge in order to make room for faith acknowledges a religious or theological telos to the entire critical project. This article outlines a series of relations of 'knowledge' to 'faith' in the architectonic repetitions with variation that plays from the first Critique through the Religion. Various deployments of 'truth' at each stage presume a kind of 'faith' or trust all the way along. These deployments are shown (...)
     
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  12.  51
    The empiricist looks at a poem.Gene Fendt - 1997 - Philosophy and Literature 21 (2):306-318.
    Why would an empiricist look at a poem? And if he did, what could he find? This paper begins with Hume's programmatic statement for literary renewal based on the empirical principles set forth in the first Enquiry, and raises the question about the worth of poetry according to those principles. There is little "abstract reasoning concerning quantity or number, or experimental reasoning concerning matter of fact and existence" in poetry and so "commit it to the flames." The second Enquiry allows (...)
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  13.  81
    Physicality for Physicalists.D. Gene Witmer - 2018 - Topoi 37 (3):457-472.
    How should the “physical” in “physicalism” be understood? I here set out systematic criteria of adequacy, propose an account, and show how the account meets those criteria. The criteria of adequacy focus on the idea of rational management: to vindicate philosophical practice, the account must make it plausible that we can assess various questions about physicalism. The account on offer is dubbed the “Ideal Naturalist Physics” account, according to which the physical is that which appears in an ideal theory that (...)
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  14.  56
    Dual carving and minimal rationalism.D. Gene Witmer - 2021 - Analytic Philosophy 62 (3):223-234.
    In his Consciousness and Fundamental Reality (2017) Philip Goff defends his anti-physicalist argument against what he calls the "Dual Carving" objection—the idea that two representations of the very same fact could both be conceptually independent and "transparent," that is, revealing of the essences of the entities in question. His defense invokes a thesis he calls "Minimal Rationalism." I explore exactly how Minimal Rationalism is supposed to turn aside the objection and argue that the formulation of Minimal Rationalism (...)
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  15. How to be a (sort of) A Priori physicalist.D. Gene Witmer - 2006 - Philosophical Studies 131 (1):185-225.
    What has come to be known as “a priori physicalism” is the thesis, roughly, that the non-physical truths in the actual world can be deduced a priori from a complete physical description of the actual world. To many contemporary philosophers, a priori physicalism seems extremely implausible. In this paper I distinguish two kinds of a priori physicalism. One sort – strict a priori physicalism – I reject as both unmotivated and implausible. The other sort – liberal a priori physicalism – (...)
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  16.  59
    Book review: Mimesis: Culture, Art, Society. [REVIEW]Gene Fendt - 1997 - Philosophy and Literature 21 (1):199-201.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Mimesis: Culture, Art, SocietyGene FendtMimesis: Culture, Art, Society, by Gunter Gebauer and Christoph Wulf; translated by Don Reneau; 400 pp. Berkeley: University of California Press, 1995, $45.00 cloth, $18.00 paper.The purpose of this book is to develop “a historical reconstruction of important phases in the development of mimesis” (p. 1) from a brief discussion of its pre-Platonic Greek significance through contemporary thinkers. It is, then, not strictly a (...)
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  17. Three overlooked key functional classes for building up minimal synthetic cells.Antoine Danchin - 2021 - Synthetic Biology 6 (1):ysab010.
    Assembly of minimal genomes revealed many genes encoding unknown functions. Three overlooked functional categories account for some of them. Cells are prone to make errors and age. As a first key function, discrimination between proper and changed entities is indispensable. Discrimination requires management of information, an authentic, yet abstract, cur- rency of reality. For example proteins age, sometimes very fast. The cell must identify, then get rid of old proteins without destroying young ones. Implementing discrimination in cells leads to (...)
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  18.  22
    The Uroboros Theory of Life’s Origin: 22-Nucleotide Theoretical Minimal RNA Rings Reflect Evolution of Genetic Code and tRNA-rRNA Translation Machineries.Jacques Demongeot & Hervé Seligmann - 2019 - Acta Biotheoretica 67 (4):273-297.
    Theoretical minimal RNA rings attempt to mimick life’s primitive RNAs. At most 25 22-nucleotide-long RNA rings code once for each biotic amino acid, a start and a stop codon and form a stem-loop hairpin, resembling consensus tRNAs. We calculated, for each RNA ring’s 22 potential splicing positions, similarities of predicted secondary structures with tRNA vs. rRNA secondary structures. Assuming rRNAs partly derived from tRNA accretions, we predict positive associations between relative secondary structure similarities with rRNAs over tRNAs and genetic (...)
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  19.  23
    Evolution of reduced prokaryotic genomes and the minimal cell concept: Variations on a theme.Luis Delaye & Andrés Moya - 2010 - Bioessays 32 (4):281-287.
    Prokaryotic genomes of endosymbionts and parasites are examples of naturally evolved minimal cells, the study of which can shed light on life in its minimum form. Their diverse biology, their lack of a large set of orthologous genes and the existence of essential linage (and environmentally) specific genes all illustrate the diversity of genes building up naturally evolved minimal cells. This conclusion is reinforced by the fact that sometimes the same essential function is performed by genes from different (...)
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  20.  25
    Research on small genomes: implications for synthetic biology.Lisa Klasson & Siv G. E. Andersson - 2010 - Bioessays 32 (4):288-295.
    Synthetic genomics is a new field of research in which small DNA pieces are assembled in a series of steps into whole genomes. The highly reduced genomes of host‐associated bacteria are now being used as models for de novo synthesis of small genomes in the laboratory. Bacteria with the smallest genomes identified in nature provide nutrients to their hosts, such as amino acids, co‐factors and vitamins. Comparative genomics of these bacteria enables predictions to be made about the gene sets (...)
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  21.  23
    Minimally incomplete sets of Ł ukasiewiczian truth functions.Herbert E. Hendry - 1983 - Notre Dame Journal of Formal Logic 24 (1):146-150.
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  22.  14
    Expressed gene sets: How different in different Tissues?A. S. Wilkins - 1985 - Bioessays 2 (2):80-82.
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  23.  26
    A minimal predicative set theory.Franco Montagna & Antonella Mancini - 1994 - Notre Dame Journal of Formal Logic 35 (2):186-203.
  24.  22
    Relevant deduction and minimally inconsistent sets.Keith Lehrer - 1973 - Philosophia 3 (2-3):153-165.
  25.  23
    Preventing a paradigm shift: A plea for the computational genome.Carmine Garzillo & Giuseppe Trautteur - 2012 - Behavioral and Brain Sciences 35 (5):365-366.
    Against the opinion that DNA as program is not sufficiently explanatory, we maintain that the cellular machinery is entirely computational, and we identify the crucial notion of the interpreter that expresses the gene with the minimal gene set. Epigenetics research does not so much need paradigm shifts as the unraveling of an exceedingly complex computational machine.
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  26.  22
    On the Turing degrees of minimal index sets.Jason Teutsch - 2007 - Annals of Pure and Applied Logic 148 (1):63-80.
    We study generalizations of shortest programs as they pertain to Schaefer’s problem. We identify sets of -minimal and -minimal indices and characterize their truth-table and Turing degrees. In particular, we show , , and that there exists a Kolmogorov numbering ψ satisfying both and . This Kolmogorov numbering also achieves maximal truth-table degree for other sets of minimal indices. Finally, we show that the set of shortest descriptions, , is 2-c.e. but not co-2-c.e. Some open problems are (...)
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  27.  1
    A min-flow algorithm for Minimal Critical Set detection in Resource Constrained Project Scheduling.Michele Lombardi & Michela Milano - 2012 - Artificial Intelligence 182-183 (C):58-67.
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  28.  16
    Unique persons and the replicable gene-sets of their reproducible bodies: a defence of human cloning.Hugh V. McLachlan - 2005 - Human Reproduction and Genetic Ethics 11 (2).
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  29.  30
    Setting risk thresholds in biomedical research: lessons from the debate about minimal risk.Annette Rid - 2014 - Monash Bioethics Review 32 (1-2):63-85.
    One of the fundamental ethical concerns about biomedical research is that it frequently exposes participants to risks for the benefit of others. To protect participants’ rights and interests in this context, research regulations and guidelines set out a mix of substantive and procedural requirements for research involving humans. Risk thresholds play an important role in formulating both types of requirements. First, risk thresholds serve to set upper risk limits in certain types of research. Second, risk thresholds serve to demarcate risk (...)
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  30. Omnipresent Maxwell’s demons orchestrate information management in living cells.Antoine Danchin Gregory Boel, Olivier Danot, Victor de Lorenzo & Antoine Danchin - 2019 - Microbial Biotechnology 12 (2):210-242.
    The development of synthetic biology calls for accurate understanding of the critical functions that allow construction and operation of a living cell. Besides coding for ubiquitous structures, minimal genomes encode a wealth of functions that dissipate energy in an unanticipated way. Analysis of these functions shows that they are meant to manage information under conditions when discrimination of substrates in a noisy background is preferred over a simple recognition process. We show here that many of these functions, including transporters (...)
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  31.  6
    A Minimal Set Low for Speed.Rod Downey & Matthew Harrison-Trainor - 2022 - Journal of Symbolic Logic 87 (4):1693-1728.
    An oracle A is low-for-speed if it is unable to speed up the computation of a set which is already computable: if a decidable language can be decided in time $t(n)$ using A as an oracle, then it can be decided without an oracle in time $p(t(n))$ for some polynomial p. The existence of a set which is low-for-speed was first shown by Bayer and Slaman who constructed a non-computable computably enumerable set which is low-for-speed. In this paper we answer (...)
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  32.  65
    Presburger sets and p-minimal fields.Raf Cluckers - 2003 - Journal of Symbolic Logic 68 (1):153-162.
    We prove a cell decomposition theorem for Presburger sets and introduce a dimension theory for Z-groups with the Presburger structure. Using the cell decomposition theorem we obtain a full classification of Presburger sets up to definable bijection. We also exhibit a tight connection between the definable sets in an arbitrary p-minimal field and Presburger sets in its value group. We give a negative result about expansions of Presburger structures and prove uniform elimination of imaginaries for Presburger structures within the (...)
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  33. Minimal semantics.Emma Borg - 2004 - New York: Oxford University Press.
    Minimal Semantics asks what a theory of literal linguistic meaning is for - if you were to be given a working theory of meaning for a language right now, what would you be able to do with it? Emma Borg sets out to defend a formal approach to semantic theorising from a relatively new type of opponent - advocates of what she call 'dual pragmatics'. According to dual pragmatists, rich pragmatic processes play two distinct roles in linguistic comprehension: as (...)
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  34. Definable sets in Boolean ordered o-minimal structures. II.Roman Wencel - 2003 - Journal of Symbolic Logic 68 (1):35-51.
    Let (M, ≤,...) denote a Boolean ordered o-minimal structure. We prove that a Boolean subalgebra of M determined by an algebraically closed subset contains no dense atoms. We show that Boolean algebras with finitely many atoms do not admit proper expansions with o-minimal theory. The proof involves decomposition of any definable set into finitely many pairwise disjoint cells, i.e., definable sets of an especially simple nature. This leads to the conclusion that Boolean ordered structures with o-minimal theories (...)
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  35.  12
    A Minimal Model for Set Theory.Paul J. Cohen - 1965 - Journal of Symbolic Logic 30 (2):250-251.
  36.  10
    Interpretable sets in dense o-minimal structures.Will Johnson - 2018 - Journal of Symbolic Logic 83 (4):1477-1500.
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  37.  42
    Definable sets in Boolean-ordered o-minimal structures. I.Ludomir Newelski & Roman Wencel - 2001 - Journal of Symbolic Logic 66 (4):1821-1836.
    We prove weak elimination of imaginary elements for Boolean orderings with finitely many atoms. As a consequence we obtain equivalence of the two notions of o-minimality for Boolean ordered structures, introduced by C. Toffalori. We investigate atoms in Boolean algebras induced by algebraically closed subsets of Boolean ordered structures. We prove uniqueness of prime models in strongly o-minimal theories of Boolean ordered structures.
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  38. Pseudoprojective strongly minimal sets are locally projective.Steven Buechler - 1991 - Journal of Symbolic Logic 56 (4):1184-1194.
    Let D be a strongly minimal set in the language L, and $D' \supset D$ an elementary extension with infinite dimension over D. Add to L a unary predicate symbol D and let T' be the theory of the structure (D', D), where D interprets the predicate D. It is known that T' is ω-stable. We prove Theorem A. If D is not locally modular, then T' has Morley rank ω. We say that a strongly minimal set D (...)
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  39.  15
    O-minimal analytic separation of sets in dimension 2.Andreas Fischer - 2009 - Annals of Pure and Applied Logic 157 (2-3):130-138.
    We study the Hardy field associated with an o-minimal expansion of the real numbers. If the set of analytic germs is dense in the Hardy field, then we can definably analytically separate sets in , and we can definably analytically approximate definable continuous unary functions. A similar statement holds for definable smooth functions.
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  40.  41
    Immunity and Hyperimmunity for Sets of Minimal Indices.Frank Stephan & Jason Teutsch - 2008 - Notre Dame Journal of Formal Logic 49 (2):107-125.
    We extend Meyer's 1972 investigation of sets of minimal indices. Blum showed that minimal index sets are immune, and we show that they are also immune against high levels of the arithmetic hierarchy. We give optimal immunity results for sets of minimal indices with respect to the arithmetic hierarchy, and we illustrate with an intuitive example that immunity is not simply a refinement of arithmetic complexity. Of particular note here are the fact that there are three (...) index sets located in Π3 − Σ3 with distinct levels of immunity and that certain immunity properties depend on the choice of underlying acceptable numbering. We show that minimal index sets are never hyperimmune; however, they can be immune against the arithmetic sets. Lastly, we investigate Turing degrees for sets of random strings defined with respect to Bagchi's size-function s. (shrink)
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  41.  38
    Grouplike minimal sets in ACFA and in T A.Alice Medvedev - 2010 - Journal of Symbolic Logic 75 (4):1462-1488.
    This paper began as a generalization of a part of the author's PhD thesis about ACFA and ended up with a characterization of groups definable in T A . The thesis concerns minimal formulae of the form x ∈ A ∧ σ(x) = f(x) for an algebraic curve A and a dominant rational function f: A → σ(A). These are shown to be uniform in the Zilber trichotomy, and the pairs (A, f) that fall into each of the three (...)
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  42.  9
    Minimal sets on propositional formulae. Problems and reductions.Joao Marques-Silva, Mikoláš Janota & Carlos Mencía - 2017 - Artificial Intelligence 252 (C):22-50.
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  43.  29
    Minimal elementary extensions of models of set theory and arithmetic.Ali Enayat - 1990 - Archive for Mathematical Logic 30 (3):181-192.
    TheoremEvery model of ZFChas a conservative elementary extension which possesses a cofinal minimal elementary extension.An application of Boolean ultrapowers to models of full arithmetic is also presented.
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  44. What are the minimal requirements of rational choice? Arguments from the sequential-decision setting.Katie Siobhan Steele - 2010 - Theory and Decision 68 (4):463-487.
    There are at least two plausible generalisations of subjective expected utility (SEU) theory: cumulative prospect theory (which relaxes the independence axiom) and Levi’s decision theory (which relaxes at least ordering). These theories call for a re-assessment of the minimal requirements of rational choice. Here, I consider how an analysis of sequential decision making contributes to this assessment. I criticise Hammond’s (Economica 44(176):337–350, 1977; Econ Philos 4:292–297, 1988a; Risk, decision and rationality, 1988b; Theory Decis 25:25–78, 1988c) ‘consequentialist’ argument for the (...)
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  45.  14
    Minimal Degrees and Recursively Inseparable Pairs of Recursively Enumerable Sets.Manuel Lerman - 1991 - Mathematical Logic Quarterly 37 (19‐22):331-342.
  46.  27
    Minimal Degrees and Recursively Inseparable Pairs of Recursively Enumerable Sets.Manuel Lerman - 1991 - Zeitschrift fur mathematische Logik und Grundlagen der Mathematik 37 (19-22):331-342.
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  47.  80
    On strongly minimal sets.J. T. Baldwin & A. H. Lachlan - 1971 - Journal of Symbolic Logic 36 (1):79-96.
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  48.  50
    DMP in Strongly Minimal Sets.Assaf Hasson & Ehud Hrushovski - 2007 - Journal of Symbolic Logic 72 (3):1019 - 1030.
    We construct a strongly minimal set which is not a finite cover of one with DMP. We also show that for a strongly minimal theory T, generic automorphisms exist iff T has DMP, thus proving a conjecture of Kikyo and Pillay.
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  49.  31
    Ultrafilters and non-Cantor minimal sets in linearly ordered dynamical systems.M. Hrušák, M. Sanchis & Á Tamariz-Mascarúa - 2008 - Archive for Mathematical Logic 47 (3):193-203.
    It is well known that infinite minimal sets for continuous functions on the interval are Cantor sets; that is, compact zero dimensional metrizable sets without isolated points. On the other hand, it was proved in Alcaraz and Sanchis (Bifurcat Chaos 13:1665–1671, 2003) that infinite minimal sets for continuous functions on connected linearly ordered spaces enjoy the same properties as Cantor sets except that they can fail to be metrizable. However, no examples of such subsets have been known. In (...)
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  50.  31
    Topological properties of sets definable in weakly o-minimal structures.Roman Wencel - 2010 - Journal of Symbolic Logic 75 (3):841-867.
    The paper is aimed at studying the topological dimension for sets definable in weakly o-minimal structures in order to prepare background for further investigation of groups, group actions and fields definable in the weakly o-minimal context. We prove that the topological dimension of a set definable in a weakly o-minimal structure is invariant under definable injective maps, strengthening an analogous result from [2] for sets and functions definable in models of weakly o-minimal theories. We pay special (...)
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