Many conserved eukaryotic traits, including apoptosis, two sexes, speciation and ageing, can be causally linked to a bioenergetic requirement for mitochondrial genes. Mitochondrial genes encode proteins involved in cell respiration, which interact closely with proteins encoded by nuclear genes. Functional respiration requires the coadaptation of mitochondrial and nuclear genes, despite divergent tempi and modes of evolution. Free‐radical signals emerge directly from the biophysics of mosaic respiratory chains encoded by two genomes prone to mismatch, with apoptosis being the default (...) penalty for compromised respiration. Selection for genomic matching is facilitated by two sexes, and optimizes fitness, adaptability and fertility in youth. Mismatches cause infertility, low fitness, hybrid breakdown, and potentially speciation. The dynamics of selection for mitonuclear function optimize fitness over generations, but the same selective processes also operate within generations, driving ageing and age‐related diseases. This coherent view of eukaryotic energetics offers striking insights into infertility and age‐related diseases. (shrink)

Recent work on a small European cave salamander (Proteus anguinus) has revealed that it has exceptional longevity, yet it appears to have unexceptional defences against oxidative damage. This paper comes at the end of a string of other studies that are calling into question the free‐radical damage theory of ageing. This theory rose to prominence in the 1990s as the dominant theory for why we age and die. Despite substantial correlative evidence to support it, studies in the last (...) five years have raised doubts over its importance. In particular, these include studies of mice with the major antioxidant genes knocked out (both singly and in combination), which show the expected elevation in oxidative damage but no impact on lifespan. Combined, these findings raise fundamental questions over whether the free‐radical damage theory remains useful for understanding the ageing process, and variation in lifespan and life histories.Editor's suggested further reading in BioEssays Blind cave salamanders age very slowly: A new member of Methuselah's Bestiary Abstract. (shrink)

The continuing viability of the free‐radical theory of ageing has been questioned following apparently incompatible recent results. We show by modelling positional effects of the generation and primary targets of reactive oxygen species that many of the apparently negative results are likely to be misleading. We conclude that there is instead a need to look more closely at the mechanisms by which free radicals contribute to age‐related dysfunction in living systems. There also needs to be deeper understanding (...) of the dynamics of accumulation and removal of the various kinds of molecular damage, in particular mtDNA mutations. Finally, the expectation that free‐radical damage on its own might cause ageing needs to be relinquished in favour of the recognition that the free‐radical theory is just one of the multiple mechanisms driving the ageing process. (shrink)

For more than a century, science has cultivated a sober public image for itself. But the truth is very different: many of our most successful scientists have more in common with libertines than librarians. This thrilling exploration of some of the greatest breakthroughs in science reveals the extreme lengths some scientists go to in order to make their theories public. Inspiration can come from the most unorthodox of places: Nobel laureates sometimes get their ideas through drugs, dreams and hallucinations. Science (...) is a highly competitive and ruthless discipline, and only its most determined and passionate practitioners make headlines - and history. That's why fraud, suppressing evidence and unethical or reckless PR games are sometimes necessary to bring the best and most brilliant discoveries to the world's attention. In science, anything goes. (shrink)

Over recent years, evidence has been accumulating in favour of the free radical theory of aging, first proposed by Harman. Despite this, an understanding of the mechanism by which cells might succumb to the effects of free radicals has proved elusive. This paper proposes such a mechanism, based on a previously unexplored hypothesis for the proliferation of mutant mitochondrial DNA: that mitochondria with reduced respiratory function, due to a mutation or deletion affecting the respiratory chain, suffer less (...) frequent lysosomal degradation, because they inflict free radical damage more slowly on their own membranes. Once such a mutation occurs in a mitochondrion of a non‐dividing cell, therefore, mitochondria carrying it will rapidly populate that cell, thereby destroying the cell's respiratory capability. The accumulation of cells that have undergone this transition results in aging at the organismal level. The consistency of the hypothesis with known facts is discussed, and technically feasible tests are suggested, of both the proposed mechanism and its overall contribution to mammalian aging. (shrink)

Only by the method of free-association could Sigmund Freud have demonstrated how human consciousness is formed by the repression of thoughts and feelings that we consider dangerous. Yet today most therapists ignore this truth about our psychic life. This book offers a critique of the many brands of contemporary psychoanalysis and psychotherapy that have forgotten Freud's revolutionary discovery. Barnaby B. Barratt offers a fresh and compelling vision of the structure and function of the human psyche, building on the pioneering (...) work of theorists such as André Green and Jean Laplanche, as well as contemporary deconstruction, feminism, and liberation philosophy. He explores how ‘drive’ or desire operates dynamically between our biological body and our mental representations of ourselves, of others, and of the world we inhabit. This dynamic vision not only demonstrates how the only authentic freedom from our internal imprisonments comes through free-associative praxis, it also shows the extent to which other models of psychoanalysis tend to stray disastrously from Freud's original and revolutionary insights. This is a vision that understands the central issues that imprison our psychic lives - the way in which the reflections of consciousness are based on the repression of our innermost desires, the way in which our erotic vitality is so often repudiated, and the way in which our socialization oppressively stifles our human spirit. Radical Psychoanalysis restores to the discipline of psychoanalysis the revolutionary impetus that has so often been lost. It will be essential reading for psychoanalysts, psychoanalytic psychotherapists, mental health practitioners and students and academics with an interest in the history of psychoanalysis. (shrink)

The free will problem and the basic alternative ways of dealing with it have been known for some 2000 years, and have engaged the greatest philosophers through the ages. In the last 50 years much philosophical progress has been added on top of that ancient cumulative understanding. Hence it would be natural to wonder why I think that any new proposal can be made on this classic problem, let alone two radical proposals.

A major obstacel to the study of mammalian development, and to the practical application of knowledge gained from it in the clinic during therapeutic in vitro fertilisation and embryo transfer (IVF‐ET), is the propensity of embryos to become retarded or arrested during their culture in vitro. The precise developmental cell cycle in which embryos arrest or delay is characteristic for the species and coincides with the earliest period of embryonic gene expression. Much evidence reviewed here implicates free oxygen radicals (...) (FORs) in the process of arrest. Thus, studies on the development of mouse preimplantation embryos in vitro have shown that (i) FORs are elevated in vitro, but not in vivo, at the time at which embryos become arrested or delayed, (ii) systems for removing reactive oxygen species to limit the formation of hydroxy radicals are present, although they have not yet been assessed quantitatively and may differ qualitatively from those in adult cells, (iii) metabolic and possibly genetic adaptations to oxidative damage are evident, (iv) published procedures for overcoming in vitro arrest are explicable in terms of FOR‐mediated damage or responses and (v) the arrest or delay of most embryos in vitro can be reduced or prevented experimentally by addition of metal chelators to limit hydroxy radical formation and lipid hydroperoxidation. (shrink)

My objective in this article is to question whether the problem of free will can, within our current conceptual system, be framed coherently. It is already widely recognized that a mental faculty, the will, needed to initiate action, no longer fits with current thought. However, we can still ask whether human decisions and actions are determined by something other than the agent. So the important question is whether we still have a cogent concept of determinism. The two prevalent alternatives (...) are a closed set of deterministic laws of nature, and a simple distillation of the principle of sufficient reason: all events must have a cause. I first provide examples showing that philosophical concepts come and go as categorial frameworks change. The modern concept of deterministic laws of nature was developed during the latter half of the modern period and is now being called seriously into question. G. W. Leibniz’s principle of sufficient reason could only be justified in theological terms, which most contemporary Western scholars reject. I end with an inadequate account of a dawning worldview based on complex adaptive systems theory, in which most human actions are best described in terms of non-necessitating propensities. (shrink)

In this article thinking on corporate social responsibility is compared with the dominant political theory of the market: theneoclassical theory. The comparison shows that thinking on CSR fundamentally collides with that theory. For example, their respectivenormative views on man are incompatible, as are their respective views on the modus operandi of the market. Given that CSR is desirable it follows that a new political theory of the market is needed. This article suggests some initial steps toward developing that new political (...) theory of the market. For example, it defends the proposition that the neoclassical idea of the market as a harmonic sphere must be replaced by the idea of the market as a fragile system. (shrink)

Free radicals are generally perceived as highly reactive species which are harmful to biological systems. There are, however, a number of enzymes that use carbon‐based radicals to catalyse a variety of important and unusual reactions. The most prominent example is ribonucleotide reductase, an enzyme which is crucial for the synthesis of DNA. In general, radicals are used to remove hydrogen from unreactive positions in the substrate, and in this way the substrate is activated to undergo chemical transformations that would (...) otherwise be difficult to achieve. Several different mechanisms have evolved which allow enzymes to generate and maintain radicals in increasingly aerobic enviroments. An unexpected finding is the existance of stable protein‐based radicals, residing on a variety of amino‐acid side chains, which serve to link the radical‐generating and catalytic sites and to store the radical between turnovers. (shrink)

Radical New Testament disciples may benefit from placing the 16th century South German Anabaptist theologian Pilgram Marpeck in conversation with the 20th century Swiss Reformed theologian Karl Barth. Marpeck and Barth will enrich ecumenical Christfollowers within both the Reformed and the Free Church traditions even as they remain confessional. Our particular effort is to construct a soteriology grounded in discipleship through correlating the coinherent work of the Word with the Spirit in revelation, through placing human agency within a (...) divinely granted response to the gracious sovereignty of God, and through providing a holistic doctrine of individual and communal life in union with Christ. (shrink)

Innovatively combining existentialist philosophy with cutting edge post-structuralist and psychoanalytic perspectives, this book boldly reconsiders market freedom. Bloom argues that present day capitalism has robbed us of our individual and collective ability to imagine and implement alternative and more progressive economic and social systems; it has deprived us of our radical freedom to choose how we live and what we can become. Since the Great Recession, capitalism has been increasingly blamed for rising inequality and feelings of mass social and (...) political alienation. In place of a deeper liberty, the free market offers subjects the opportunity to continually reinvest their personal and shared hopes within its dogmatic ideology and policies. This embrace helps to temporarily alleviate growing feelings of anxiety and insecurity at the expense of our fundamental human agency. What has become abundantly clear is that the free market is anything but free. Here, Bloom exposes our present day bad faith in the free market and how we can break free from it. (shrink)

It has been claimed that quantum mechanics, unlike classical mechanics, allows for free will. In this paper I articulate that claim and explain how a complex physical system possessing fractal-like self similarity could exhibitboth self consciousness and self determination. I use complexity theory to show how quantum mechanical indeterminacies at the neural level could “percolate up” to the levels of scale within the brain at which sensory-motor information transformations occur. Finally, I explain how macro level indeterminacy could be coupled (...) with self determination to provide a physical system with the capacity for radically free willing. (shrink)

Denialism concerning free will and moral responsibility combines, in its minimal form, the rejection of libertarian free will and the rejection of compatibilism. I will address the more ambitiously “happy” or “optimistic” version of denialism, which also claims that we are better off without belief in free will and moral responsibility, and ought to try to radically reform our moral, social and personal lives without such beliefs. I argue that such denialism involves, for various reasons, a dangerous (...) gamble, which it would be morally irresponsible to follow. I conclude by reflecting upon the implications. (shrink)

Where does the notion of free will come from? How and when did it develop, and what did that development involve? In Michael Frede's radically new account of the history of this idea, the notion of a free will emerged from powerful assumptions about the relation between divine providence, correctness of individual choice, and self-enslavement due to incorrect choice. Anchoring his discussion in Stoicism, Frede begins with Aristotle--who, he argues, had no notion of a free will--and ends (...) with Augustine. Frede shows that Augustine, far from originating the idea, derived most of his thinking about it from the Stoicism developed by Epictetus. (shrink)

Most people assume that, even though some degenerative or criminal behavior may be caused by influences beyond our control, ordinary human actions are not similarly generated, but rather are freely chosen, and we can be praiseworthy or blameworthy for them. A less popular and more radical claim is that factors beyond our control produce all of the actions we perform. It is this hard determinist stance that Derk Pereboom articulates in Living Without Free Will. Pereboom argues that our (...) best scientific theories have the consequence that factors beyond our control produce all of the actions we perform, and that because of this, we are not morally responsible for any of them. He seeks to defend the view that morality, meaning and value remain intact even if we are not morally responsible, and furthermore, that adopting this perspective would provide significant benefit for our lives. (shrink)

Do humans have a free choice of which actions to perform? Three recent developments of modern science can help us to answer this question. First, new investigative tools have enabled us to study the processes in our brains which accompanying our decisions. The pioneer work of Benjamin Libet has led many neuroscientists to hold the view that our conscious intentions do not cause our bodily movements but merely accompany them. Then, Quantum Theory suggests that not all physical events are (...) fully determined by their causes, and so opens the possibility that not all brain events may be fully determined by their causes, and so maybe - if neuroscience does not rule this out - there is a role for intentions after all. Finally, a theorem of mathematics, Godel's theory, has been interpreted to suggest that the initial conditions and laws of development of a mathematician's brain could not fully determine which mathematical conjectures he sees to be true. Papers by Patrick Haggard, Tim Bayne, Harald Atmanspacher and Stefan Rotter, Solomon Feferman, and John Lucas investigate these issues. The extent to which human behaviour is determined by brain events may well depend on whether conscious events, such as intentions, are themselves merely brain events, or whether they are separate events which interact with brain events (perhaps in the radical form that intentions are events in our soul, and not in our body). The papers of Frank Jackson, Richard Swinburne, and Howard Robinson investigate these issues. The remaining papers, of Galen Strawson, Helen Steward, and R.A. Duff, consider what kind of free will we need in order to be morally responsible for our actions or to be held guilty in a court of law. Is it sufficient merely that our actions are uncaused by brain events, or what? (shrink)

Ecological psychology is one of the most influential theories of perception in the embodied, anti-representational, and situated cognitive sciences. However, radical enactivists claim that Gibsonians tend to describe ecological information and its ‘pick up’ in ways that make ecological psychology close to representational theories of perception and cognition. Motivated by worries about the tenability of classical views of informational content and its processing, these authors claim that ecological psychology needs to be “RECtified” so as to explicitly resist representational readings. (...) In this paper, we argue against this call for RECtification. To do so, we offer a detailed analysis of the notion of perceptual information and other related notions such as specificity and meaning, as they are presented in the specialized ecological literature. We defend that these notions, if properly understood, remain free of any representational commitment. Ecological psychology, we conclude, does not need to be RECtified. (shrink)

Jonathan I. Israel claims that Christian ‘controversialists’ endeavoured first to obscure or efface Spinozism, materialism, and non-authoritarian free thought, and then, in the early eighteenth century, to fight these openly, and desperately. Israel appears to have adopted the view of enlightenment as a battle against what Voltaire has called ‘l’infâme’, and David Hume has labelled ‘stupidity, Christianity, and ignorance’. These authors’ barbs were launched later in the century, however, in the period of the high Enlightenment, following polarizing controversies of (...) mid-century. This chapter argues that many Enlightenment figures, including Hume and Voltaire, were far more involved within a culture in the second quarter of the century that was less divided against Christian interlocutors, less rigid, and more complex than these two wished to suggest, in retrospect, after mid-century. A Christian literary and scientific circle was productive and prominent in French Enlightenment culture, particularly in the personages of François Prévost, Pierre Desfontaines, Samuel Formey and Noël Pluche, and in the pages of ubiquitous journals and occasional publications. Many of the Catholics among these lumières held the education and retained the status of ‘abbé’, a title with prophylactic properties that legitimated expansive inquiry – into topics such as libertinism and atheism – and facilitated in-print exchanges with Voltaire and other less orthodox figures. This wing of the Enlightenment developed a culture that reflected, and sometimes promoted, Christian theology – especially in the tradition of natural theology – and displayed broadly Christian and politically conservative values. The latter aspect served in part to motivate concerted efforts toward their marginalization by others, but the French Enlightenment of the eighteenth century’s second quarter was actually very mixed, and not so very radical; rather, it became polarized at mid-century, and in retrospect, the Christians of this wing were written out of the history by the likes of Voltaire and Hume. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Toward a Radical Female Imaginary: Temporality and Embodiment in Irigaray’s EthicsEwa Plonowska Ziarek* (bio)An important intervention of Irigaray’s work on sexual difference into the postmodern debates on ethics is the mediation between two different lines of ethical inquiry: one represented by the work of Nietzsche, Deleuze, Foucault, and, to a certain degree, Castoriadis, and the other by the work of Levinas, Derrida, and Lyotard. Although the two trajectories (...) both depart from the notion of morality as a universal system of law and judgment, they represent different approaches to freedom and obligation. For Levinas, Derrida, and Lyotard, the ethical significance of alterity disrupts social systems of signification and, in this sense, marks transcendence as a break in discourse, whereas for Nietzsche, Deleuze, and Foucault, otherness is expressed within the endless variations of becoming. To elucidate this difference, it might be useful to recall John Caputo’s distinction between two kinds of postmodern ethics—the Nietzschean heteromorphism and the Levinasian heteronomy. In its emphasis on becoming and change, heteromorphism, Caputo claims, puts forward the claim of liberation but cannot accommodate an obligation to the other: “In heteromorphism, the aim is freedom from inhibition and blockage, freedom from... the weight of values... from everything that weighs the will down....” By contrast, the Levinasian ethics of alterity gives priority to the obligation to the other, which calls the freedom of the subject into question: “freedom is suspect, suspended, held in question, because it is aggressive, self-accumulative, and eventually, finally murderous. Heteronomism wants the other to be free while one is oneself held hostage” [Caputo 60].In my discussion of the radical female imaginary I would like to show that Irigaray’s work refuses to align itself with either side of this divide. Originating in the very gap between liberation and responsibility, self and other, immanence and transcendence, freedom and obligation, the feminist ethics of sexual difference cannot disregard any of these claims. For Irigaray, the ethics of sexual difference has to enable different trajectories of gendered becomings without forgetting the obligation to the other. In fact, Irigaray argues that the responsibility to the other who differs sexually is the very source of such becomings. Irigaray’s ethics maintains neither the rigid separation between freedom and obligation, as is the case in Levinas’s work, nor their symmetrical reversibility, as is the case in Kant’s ethics. By contesting the oppositions between carnal passions and ethical obligations, between the respect for the other and the becoming of the self, Irigaray allows us to think through the disjunction between the two main ethical trajectories of postmodernism and to find the means to negotiate between them. In this essay I would like [End Page 60] to focus on two moments of such negotiation: the becoming of sexed bodies and the temporality of the female imaginary.One of Irigaray’s famous claims is the charge of the forgetting of sexed bodies in the discourses of philosophy, science, linguistics, and politics. Although this claim is certainly not new in feminist theory, what is original in Irigaray’s work is the diagnosis of the numerous symptoms of such forgetting, for instance, the relation she makes between the erasure of the sexed body and the nihilism of Western culture. For Irigaray, the forgetting of sexual difference manifests itself not only in the disregard for the specificity of feminine embodiment, desires, and genealogies but also in the disembodied character of linguistic analyses, in the erasure of the drama of enunciation evident in the privilege given to predication, in the separation of the subject of knowledge from carnality and desire, in the infatuation with formalism and with its obverse side, the crippling nostalgia for the maternal body, and, finally, in the rigid separation between the immanence of flesh and the transcendence of the spirit. 1 Even more striking is the originality of Irigaray’s intervention, which links the question of sexual difference with the temporality of the body.An important element of Irigaray’s ethics of sexual difference is the recovery of “that repressed entity, the female imaginary” [TS 28]. Despite numerous excellent discussions of the imaginary in Irigaray’s work, the complexity of her negotiations around this... (shrink)

Radical ontic structural realism (ROSR) asserts an ontological commitment to ‘free-standing’ physical structures understood solely in terms of fundamental relations, without any recourse to relata that stand in these relations. Bain ([2013], pp.1621–35) has recently defended ROSR against the common charge of incoherence by arguing that a reformulation of fundamental physical theories in category-theoretic terms (rather than the usual set-theoretic ones) offers a coherent and precise articulation of the commitments accepted by ROSR. In this essay, we argue that (...) category theory does not offer a more hospitable environment to ROSR than set theory. We also show that the application of category-theoretic tools to topological quantum field theory and to algebraic generalizations of general relativity do not warrant the claim that these theories describe ‘object-free’ structures. We conclude that category theory offers little if any comfort to ROSR. 1 Introduction: Ridding Structures of Objects2 The Set-theoretic Peril for Radical Ontic Structural Realism3 Bain’s Categorial Strategy to Save Radical Ontic Structural Realism4 Throwing out the Relations with the Relata5 Categorial and Set-theoretical Structures6 Radical Suggestions from Topological Quantum Field Theory?7 Sheaves of Einstein Algebras as Radical Structures?8 Conclusions. (shrink)

Jonathan I. Israel claims that Christian ‘controversialists’ endeavoured first to obscure or efface Spinozism, materialism, and non-authoritarian free thought, and then, in the early eighteenth century, to fight these openly, and desperately. Israel appears to have adopted the view of enlightenment as a battle against what Voltaire has called ‘l’infâme’, and David Hume has labelled ‘stupidity, Christianity, and ignorance’. These authors’ barbs were launched later in the century, however, in the period of the high Enlightenment, following polarizing controversies of (...) mid-century. This chapter argues that many Enlightenment figures, including Hume and Voltaire, were far more involved within a culture in the second quarter of the century that was less divided against Christian interlocutors, less rigid, and more complex than these two wished to suggest, in retrospect, after mid-century. A Christian literary and scientific circle was productive and prominent in French Enlightenment culture, particularly in the personages of François Prévost, Pierre Desfontaines, Samuel Formey and Noël Pluche, and in the pages of ubiquitous journals and occasional publications. Many of the Catholics among these lumières held the education and retained the status of ‘abbé’, a title with prophylactic properties that legitimated expansive inquiry – into topics such as libertinism and atheism – and facilitated in-print exchanges with Voltaire and other less orthodox figures. This wing of the Enlightenment developed a culture that reflected, and sometimes promoted, Christian theology – especially in the tradition of natural theology – and displayed broadly Christian and politically conservative values. The latter aspect served in part to motivate concerted efforts toward their marginalization by others, but the French Enlightenment of the eighteenth century’s second quarter was actually very mixed, and not so very radical; rather, it became polarized at mid-century, and in retrospect, the Christians of this wing were written out of the history by the likes of Voltaire and Hume. (shrink)

Jonathan I. Israel claims that Christian ‘controversialists’ endeavoured first to obscure or efface Spinozism, materialism, and non-authoritarian free thought, and then, in the early eighteenth century, to fight these openly, and desperately. Israel appears to have adopted the view of enlightenment as a battle against what Voltaire has called ‘l’infâme’, and David Hume has labelled ‘stupidity, Christianity, and ignorance’. These authors’ barbs were launched later in the century, however, in the period of the high Enlightenment, following polarizing controversies of (...) mid-century. This chapter argues that many Enlightenment figures, including Hume and Voltaire, were far more involved within a culture in the second quarter of the century that was less divided against Christian interlocutors, less rigid, and more complex than these two wished to suggest, in retrospect, after mid-century. A Christian literary and scientific circle was productive and prominent in French Enlightenment culture, particularly in the personages of François Prévost, Pierre Desfontaines, Samuel Formey and Noël Pluche, and in the pages of ubiquitous journals and occasional publications. Many of the Catholics among these lumières held the education and retained the status of ‘abbé’, a title with prophylactic properties that legitimated expansive inquiry – into topics such as libertinism and atheism – and facilitated in-print exchanges with Voltaire and other less orthodox figures. This wing of the Enlightenment developed a culture that reflected, and sometimes promoted, Christian theology – especially in the tradition of natural theology – and displayed broadly Christian and politically conservative values. The latter aspect served in part to motivate concerted efforts toward their marginalization by others, but the French Enlightenment of the eighteenth century’s second quarter was actually very mixed, and not so very radical; rather, it became polarized at mid-century, and in retrospect, the Christians of this wing were written out of the history by the likes of Voltaire and Hume. (shrink)

European Journal of Political Theory, Volume 21, Issue 1, Page 25-46, January 2022. This article explains how 19th-century radical republicans answered the following question: how is it possible to be free in a social order that fosters economic dependence on others? I focus on the writings of a group of French thinkers called the solidarists who advocated “liberty organized for everyone.” Mutualism and social right were two components of the solidarist strategy for limiting domination in commercial/industrial society. While (...) the doctrine of mutualism was rooted in pre-industrial artisan culture, social right was a novel idea that built on Durkheim’s analysis of the division of labour. In this article, I describe the main features of the solidarist account: solidarity, social property, quasi-contractual debt, and restorative justice. Classical republicanism was deeply concerned with citizen participation and the balance between popular and elite power, but 19th-century radical republicans thought that these goals must be approached differently in market societies in which enormous power is exercised outside the state. The solidarists cautiously embraced the state as a mechanism for regulating the market in order to ensure equal liberty. Social right and mutualism were also conceived as ways of limiting the centralization of state power. (shrink)

The no free lunch theorem is a radicalized version of Hume’s induction skepticism. It asserts that relative to a uniform probability distribution over all possible worlds, all computable prediction algorithms—whether ‘clever’ inductive or ‘stupid’ guessing methods —have the same expected predictive success. This theorem seems to be in conflict with results about meta-induction. According to these results, certain meta-inductive prediction strategies may dominate other methods in their predictive success. In this article this conflict is analyzed and dissolved, by means (...) of probabilistic analysis and computer simulation. (shrink)

This paper sets Scott’s original film Blade Runner (1982) and Villeneuve’s Blade Runner 2049 (2017) in a ‘disjunctive synthesis’ in order to provide critical analyses of both films with respect to some complex configurations of the body along two axes: bio-politics and the spectacle. We offer a reading of these configurations by focusing on the relationships between the human (organic), the non-human (android) and the immaterial (holographic); the eye (optics), the hand (haptics), and aesthetics; slavery, instrumental labour and free-play; (...) the politics of bodies and of memories; the potentialities of revolution and the transmission of ‘tradition of the oppressed’. In this, we foreground two seemingly marginal characters – J. F. Sebastian and Ana Stelline. These ‘little people’ embody and inhabit the convolutions of Blade Runner’s ‘more human than human’ world through ‘free use’ of the body and playfulness which, superficially innocent, nevertheless bear within them the promise of radical political change. (shrink)

Foucault’s invitation to the subject is to become free of themselves by learning to think differently. Such a project has as its goal the mastery of the self, and can be understood as a Foucaultian ‘politics of ourselves’. Foucault’s ethical turn is an invitation for subjectivity to undertake its own radical education. Whilst this invitation has characteristics unique to Foucault’s philosophical discipline, I argue that it sheds light upon a diversity of practices of subjectivity from the psychotherapeutic and (...) mystic traditions. By seeing these currently available technologies of self in the Foucaultian lens we are given the opportunity to appreciate their work on subjectivity as necessarily political and social, a radical education not limited to the realm of individualistic aspiration and narcissistic temptations. The paper concludes by drawing attention to some implications for education, and for a teacher education that embraces the ‘radical reflexivity’ of some psycho-spiritual practices. (shrink)

The aim of this paper is to give a description of the free algebras in some varieties of Glivenko MTL-algebras having the Boolean retraction property. This description is given (generalizing the results of [9]) in terms of weak Boolean products over Cantor spaces. We prove that in some cases the stalks can be obtained in a constructive way from free kernel DL-algebras, which are the maximal radical of directly indecomposable Glivenko MTL-algebras satisfying the equation in the title. (...) We include examples to show how we can apply the results to describe free algebras in some well known varieties of involutive MTL-algebras and of pseudocomplemented MTL-algebras. (shrink)

The aim of this paper is to give a description of the free algebras in some varieties of Glivenko MTL-algebras having the Boolean retraction property. This description is given (generalizing the results of [9]) in terms of weak Boolean products over Cantor spaces. We prove that in some cases the stalks can be obtained in a constructive way from free kernel DL-algebras, which are the maximal radical of directly indecomposable Glivenko MTL-algebras satisfying the equation in the title. (...) We include examples to show how we can apply the results to describe free algebras in some well known varieties of involutive MTL-algebras and of pseudocomplemented MTL-algebras. (shrink)

It’s been agreed for decades that not only does Determinism pose a big problem for our choosing from available alternatives, but its denial seems to pose a bit of a problem, too. It’s argued here that only Determinism, and not its denial, means no real choice for us.But, what explains the appeal of the thought that, where things aren’t fully determined, to that extent they’re just a matter of chance? It's the dominance of metaphysical suppositions that, together, comprise Scientiphicalism: Wholly (...) composed of such mindless physical parts as electrons, you are a being whose powers are all physical powers, physically deriving from the powers of your parts and their physical arrangements. Scientiphicalisrn conflicts with your having real choice.Some fairly conservative alternatives to Scientiphicalism may allow for choice. Two are briefly discussed: On the further-fetched, you are a Cartesian mental being, a nonphysical being in powerful interaction with physical things. On the more conservative approach, you are wholly composed of physical parts, but some of your powers are radically emergent, including your power to choose.Finally, it’s argued that, if you choose, you must be, to some extent, exempt from natural laws. (shrink)

Applying fresh tools from economics to explain puzzling behaviors of religious radicals: Muslim, Christian, and Jewish; violent and benign. How do radical religious sects run such deadly terrorist organizations? Hezbollah, Hamas, Lashkar-e-Taiba, and the Taliban all began as religious groups dedicated to piety and charity. Yet once they turned to violence, they became horribly potent, executing campaigns of terrorism deadlier than those of their secular rivals. In Radical, Religious, and Violent, Eli Berman approaches the question using the economics (...) of organizations. He first dispels some myths: radical religious terrorists are not generally motivated by the promise of rewards in the afterlife (including the infamous seventy-two virgins) or even by religious ideas in general. He argues that these terrorists (even suicide terrorists) are best understood as rational altruists seeking to help their own communities. Yet despite the vast pool of potential recruits—young altruists who feel their communities are repressed or endangered—there are less than a dozen highly lethal terrorist organizations in the world capable of sustained and coordinated violence that threatens governments and makes hundreds of millions of civilians hesitate before boarding an airplane. What's special about these organizations, and why are most of their followers religious radicals? Drawing on parallel research on radical religious Jews, Christians, and Muslims, Berman shows that the most lethal terrorist groups have a common characteristic: their leaders have found a way to control defection. Hezbollah, Hamas, and the Taliban, for example, built loyalty and cohesion by means of mutual aid, weeding out “free riders” and producing a cadre of members they could rely on. The secret of their deadly effectiveness lies in their resilience and cohesion when incentives to defect are strong.These insights suggest that provision of basic social services by competent governments adds a critical, nonviolent component to counterterrorism strategies. It undermines the violent potential of radical religious organizations without disturbing free religious practice, being drawn into theological debates with Jihadists, or endangering civilians. (shrink)

Review of Van Parijs and Vanderborght's book, Basic Income: A Radical Proposal for a Free Society and a Sane Economy. Van Parijs refers to this book as not only a "toolkit for the people advocating Basic Income around the world, but also for people criticizing it." This book is a must-read for anyone interested in Basic Income.

I argue that a powers-based metaphysics radically reconfigures the existing free will problematic. This is different from claiming that such an approach solves the ill-conceived problems that emerge from Humean-Kantian default commitments.

The main claim of this thesis is that value-judgments should play a profound role in the construction and evaluation of species classifications. The arguments for this claim will be presented over the course of five chapters. These are divided into two main parts; part one, which consists of the two first chapters, presents an argument for a radical form of species pluralism; part two, which comprises the remaining chapters, discusses the implications of radical species pluralism for the role (...) of values in species classification. The content of the five chapters is as follows. Chapter 1 starts with a discussion of the theoretical assumptions concerning species and natural kinds that form the broad framework within which the arguments of the thesis are placed. The aim of this chapter is to introduce a set of relatively uncontroversial assumptions that frame the rest of the thesis. On the basis of these assumptions, chapter 2 presents an argument for radical species pluralism. The chapter substantiates this argument with a broad range of examples, and compares this position to other forms of species pluralism. Chapter 3 returns to the main interest of the thesis, namely, the role of values in species classification. It introduces the notion of values and presents an argument for the value-ladenness of taxonomy on the basis of the considerations in the first two chapters. It then sketches three important views on values in science in the literature. Chapter 4 argues that the case presented in chapter 3 provides strong support for one of these views, called the ‘Aims View’, and against two other prominent views, called the ‘Epistemic Priority View’ and the ‘Value-Free Ideal’. The resulting view, in line with the Aims View, is that value-judgments should play a particularly substantial role in species classification. Chapter 5 then considers the popular assumption that these value-judgments in taxonomy commonly take the shape of generally accepted classificatory norms, and argues that this assumption is not tenable. Finally, a brief concluding chapter points at some implications of the claims and arguments in this thesis. (shrink)

This article explains how 19th-century radical republicans answered the following question: how is it possible to be free in a social order that fosters economic dependence on others? I focus on the writings of a group of French thinkers called the solidarists who advocated “liberty organized for everyone.” Mutualism and social right were two components of the solidarist strategy for limiting domination in commercial/industrial society. While the doctrine of mutualism was rooted in pre-industrial artisan culture, social right was (...) a novel idea that built on Durkheim’s analysis of the division of labour. In this article, I describe the main features of the solidarist account: solidarity, social property, quasi-contractual debt, and restorative justice. Classical republicanism was deeply concerned with citizen participation and the balance between popular and elite power, but 19th-century radical republicans thought that these goals must be approached differently in market societies in which enormous power is exercised outside the state. The solidarists cautiously embraced the state as a mechanism for regulating the market in order to ensure equal liberty. Social right and mutualism were also conceived as ways of limiting the centralization of state power. (shrink)

The notion of radical evil plays a more important role in Kant's moral theory than is typically recognized. In Religion Within the Limits of Mere Reason, radical evil is both an innate propensity and a morally imputable act – a paradoxical status that has prompted commentators to reject it as inconsistent with the rest of Kant's moral theory. In contrast, I argue that the notion of radical evil accounts for the beginning of moral responsibility in Kant's theory, (...) since the act of attributing radical evil to one's freedom is an inauguration into the autonomous stance.Send article to KindleTo send this article to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle. Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply. Find out more about the Kindle Personal Document Service.Kant on Radical Evil and the Origin of Moral ResponsibilityVolume 18, Issue 1Irene McMullin DOI: https://doi.org/10.1017/S1369415412000283Your Kindle email address Please provide your Kindle email.@free[email protected] Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Dropbox To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Dropbox. Kant on Radical Evil and the Origin of Moral ResponsibilityVolume 18, Issue 1Irene McMullin DOI: https://doi.org/10.1017/S1369415412000283Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Send article to Google Drive To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Google Drive. Kant on Radical Evil and the Origin of Moral ResponsibilityVolume 18, Issue 1Irene McMullin DOI: https://doi.org/10.1017/S1369415412000283Available formats PDF Please select a format to send. By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel Send ×Export citation. (shrink)

Applying fresh tools from economics to explain puzzling behaviors of religious radicals: Muslim, Christian, and Jewish; violent and benign. How do radical religious sects run such deadly terrorist organizations? Hezbollah, Hamas, Lashkar-e-Taiba, and the Taliban all began as religious groups dedicated to piety and charity. Yet once they turned to violence, they became horribly potent, executing campaigns of terrorism deadlier than those of their secular rivals. In Radical, Religious, and Violent, Eli Berman approaches the question using the economics (...) of organizations. He first dispels some myths: radical religious terrorists are not generally motivated by the promise of rewards in the afterlife (including the infamous seventy-two virgins) or even by religious ideas in general. He argues that these terrorists (even suicide terrorists) are best understood as rational altruists seeking to help their own communities. Yet despite the vast pool of potential recruits—young altruists who feel their communities are repressed or endangered—there are less than a dozen highly lethal terrorist organizations in the world capable of sustained and coordinated violence that threatens governments and makes hundreds of millions of civilians hesitate before boarding an airplane. What's special about these organizations, and why are most of their followers religious radicals? Drawing on parallel research on radical religious Jews, Christians, and Muslims, Berman shows that the most lethal terrorist groups have a common characteristic: their leaders have found a way to control defection. Hezbollah, Hamas, and the Taliban, for example, built loyalty and cohesion by means of mutual aid, weeding out “free riders” and producing a cadre of members they could rely on. The secret of their deadly effectiveness lies in their resilience and cohesion when incentives to defect are strong.These insights suggest that provision of basic social services by competent governments adds a critical, nonviolent component to counterterrorism strategies. It undermines the violent potential of radical religious organizations without disturbing free religious practice, being drawn into theological debates with Jihadists, or endangering civilians. (shrink)

In our present-day Western society, there has been an increasing tendency towards individualism and indifference and away from altruism and empathy. This has led to a resurgence of ethical concerns in contemporary Continental philosophy. Following the thinking of philosophers such as Emmanuel Levinas, ethics has come to be defined in terms of a disinterested and selfless concern for the well-being of others. Levinas claims that taking care of others in need is not a free, rational decision, but a fundamental (...) responsibility that is pre-consciously felt. We are passively obligated before we can actively choose to help. Levinas therefore argues that the needy other incapacitates our normal selfish ways, and that this ‘radical passivity’ enables us to recognise our inherent responsibility towards others in need. Levinas's own thinking on this subject is not unambiguous, however. While his early works stress the fact that we cannot care for others if we do not first take care of ourselves, his later works focus exclusively on the other as locus of our ethical responsibility. Following this line of thinking, a false opposition has emerged between an absolutised egoism and a crushing altruism that threatens to undermine the recent resurgence of ethical concerns. For how can we continue to care for others if we fail to recognise the duties we have towards ourselves? Moreover, what is the moral significance of responsible action if it is not freely chosen but passively imposed? (shrink)

In Part I, I reflect in some detail upon the free will problem and about the way its understanding has radically changed. First I outline the four questions that go into making the free will problem. Second, I consider four paradigmatic shifts that have occurred in our understanding of this problem. Then I go on to reflect upon this complex and multi-level situation. In Part II of this essay, I explore the major alternative positions, and defend my views, (...) in new ways. Instead of trying to spread over many issues, I present one new argument against compatibilism, which I call “The Trap”. This tries to explicate the main problem that I find with this position. Then I present an exposition of what we nevertheless need to follow, which I call “the Appreciation of Agency”. This supports a measure of compatibilism in a more modest form, and opposes hard determinism. On this basis, we can confront the philosophical and practical questions, as to what we ought to believe and how we ought to live, with respect to free will and moral responsibility. This leads to what I call “The Bubble,” which addresses the way in which we deal with the tension between the absence of libertarian free will and The Trap, and the crucial need for the Appreciation of Agency. I conclude by reflecting upon three attributes of the free will problem that I consider central, but that have been neglected in the debate: complexity, risk and tragedy. (shrink)

In the Ethics, Spinoza famously rejects freedom of the will. He also offers an error theory for why many believe, falsely, that the will is free. Standard accounts of his arguments for these claims focus on their efficacy against incompatibilist views of free will. For Spinoza, the will cannot be free since it is determined by an infinite chain of external causes. And the pervasive belief in free will arises from a structural limitation of our self-knowledge: (...) because we are aware of our actions but unaware of their causes, we suppose that we alone must be responsible for them. Yet I argue that the standard accounts miss a further element of Spinoza’s arguments that also targets compatibilist views on which free will is consistent with a specific kind of determination—namely, self-determination in accordance with our value judgments. For Spinoza, we are misled not only in supposing that our actions lack external determination but also in thinking that they are determined by our representations of value. In fact, our actions are determined by our appetites, which are blind to our value judgments. And the pervasive belief that our actions are determined by such judgments arises from the projection of value onto the objects we seek. As he denies us free will, then, Spinoza also denies us a capacity central to agency—the capacity to determine our actions in accordance with our ideas of the good. This makes his arguments against free will more consequential, and more radical, than commonly assumed. (shrink)

Contemporary civil libertarians claim that their works preserve a worthy American tradition of defending free-speech rights dating back to the framing of the First Amendment. _Transforming Free Speech_ challenges the worthiness, and indeed the very existence of one uninterrupted libertarian tradition. Mark A. Graber asserts that in the past, broader political visions inspired libertarian interpretations of the First Amendment. In reexamining the philosophical and jurisprudential foundations of the defense of expression rights from the Civil War to the present, (...) he exposes the monolithic free-speech tradition as a myth. Instead of one conception of the system of free expression, two emerge: the conservative libertarian tradition that dominated discourse from the Civil War until World War I, and the civil libertarian tradition that dominates later twentieth-century argument. The essence of the current perception of the American free-speech tradition derives from the writings of Zechariah Chafee, Jr., the progressive jurist most responsible for the modern interpretation of the First Amendment. His interpretation, however, deliberately obscured earlier libertarian arguments linking liberty of speech with liberty of property. Moreover, Chafee stunted the development of a more radical interpretation of expression rights that would give citizens the resources and independence necessary for the effective exercise of free speech. Instead, Chafee maintained that the right to political and social commentary could be protected independent of material inequalities that might restrict access to the marketplace of ideas. His influence enfeebled expression rights in a world where their exercise depends increasingly on economic power. Untangling the libertarian legacy, Graber points out the disjunction in the libertarian tradition to show that free-speech rights, having once been transformed, can be transformed again. Well-conceived and original in perspective, _Transforming Free Speech_ will interest political theorists, students of government, and anyone interested in the origins of the free-speech tradition in the United States. (shrink)