A general framework by which dynamic interactions within a protein will promote the necessary series of structural changes, or “conformational cycle,” required for function is proposed. It is suggested that the free‐energy landscape of a protein is biased toward this conformational cycle. Fluctuations into higher energy, although thermally accessible, conformations drive the conformational cycle forward. The amino acid interaction network is defined as those intraprotein interactions that contribute most to the free‐energy landscape. Some network connections are consistent in (...) every structural state, while others periodically change their interaction strength according to the conformational cycle. It is reviewed here that structural transitions change these periodic network connections, which then predisposes the protein toward the next set of network changes, and hence the next structural change. These concepts are illustrated by recent work on tryptophan synthase. Disruption of these dynamic connections may lead to aberrant protein function and disease states. (shrink)

Drive en Mille Sons (Drifting in a Thousand Sounds)is a musical work that uses mobile media technology to artistically examine the relationship between music and the listener. Contemporary media technologies, be they at work, home or in your pocket, emphasize playback. These devices are designed to facilitate the storage and retrieval of pre-made media assets. This work leverages the processing capabilities that rest dormant within these technologies. Drawing from the writings of Guy Debord and the situationist/surrealist practice of the (...) drive, drifting becomes a metaphor for instrumental performance in which the openness and emergence of interactivity is articulated through sound, as music. (shrink)

When behaviors assemble into combinations, then synergies have a central role in the discovery of productive patterns of behavior. In our view—what we call the Synergy Emergence Principle (SEP)—synergies are dynamic attractors, drawing interactions toward greater returns as they happen, in the moment. This Principle offers an alternative to the two conventionally acknowledged routes to discovery: directed problem solving, involving forethought and planning; and the complete randomness of trial and error. Natural selection has a role in the process, in humans (...) favoring the maintenance and improvement of certain key underlying capabilities, such as prosocial helping and episodic foresight, but selection is not required for discovery by synergy (which occurs too rapidly for selection anyway). Here we discuss the consequences of the SEP for the evolution in humans of key synergies such as tool usage and interactions that reward cooperation, show how discovery by synergy and the selection of synergy-supporting abilities formed a positive feedback loop, and show how synergies can combine, forming clusters and packages that are the core of institutions and cultures. Finally, clusters and packages represent an intermediate level of organization above the individual and below whole society, with consequences for our understanding of the major transitions in evolution. (shrink)

The literature on self-driving cars and ethics continues to grow. Yet much of it focuses on ethical complexities emerging from an individual vehicle. That is an important but insufficient step towards determining how the technology will impact human lives and society more generally. What must complement ongoing discussions is a broader, system level of analysis that engages with the interactions and effects that these cars will have on one another and on the socio-technical systems in which they are embedded. To (...) bring the conversation of self-driving cars to the system level, we make use of two traffic scenarios which highlight some of the complexities that designers, policymakers, and others should consider related to the technology. We then describe three approaches that could be used to address such complexities and their associated shortcomings. We conclude by bringing attention to the “Moral Responsibility for Computing Artifacts: The Rules”, a framework that can provide insight into how to approach ethical issues related to self-driving cars. (shrink)

Social media advertisement is a growing phenomenon designed to reach and engage customers. However, despite their continued adoption, less remains known regarding the effectiveness of social media ads to co-create brand value. In response to this gap, this study aims to deepen the theoretical understanding of consumer value co-creation through social media advertising value. The data were collected using purposive sampling from 286 experienced social-media users, and the model was tested using partial least square -based structural equation modeling. The results (...) indicate that entertainment, aesthetic appeal, interactivity, and trendiness significantly affect the adverting value of social media ads. In turn, ad value affects consumers’ intention for value co-creation. Consequently, our findings suggest the importance of social media advertising value where marketers may enhance consumer-brand engagement by incorporating interesting content, which may encourage the customer’s interaction with the social media ads and strengthen value co-creation behavior. The results further contribute to nascent marketing literature by demonstrating that value co-creation acts as an antecedent to generating positive electronic word-of-mouth on social media platforms to drive consumers’ online brand purchase intention. (shrink)

Part II of Fichte’s System of Ethics is titled “Deduction of the Reality and Applicability of the Moral Law.” In this chapter, I argue that what motivates Fichte’s new deduction is a concern to avoid what he calls “empty formula philosophy,” that is, a philosophy which fails to explain how willing an object is possible. Fichte sets out to avoid this shortcoming by offering a complex theory of the drives, focusing first on what he calls our “lower capacity of desire.” (...) I argue that the key to understanding this section of the System of Ethics lies in Fichte's attempt to derive the character of our “natural drive” (Naturtrieb) from how we represent the system of “nature“ (Natur) as a whole. At the centre of this derivation we find Fichte drawing upon an organicist model of nature, according to which all the parts of natural systems reciprocally interact for the sake of the whole, and vice versa. While largely overlooked by scholars, I contend that this organicist model gives Fichte the resources to present an original theory of desire as an activity of “forming and being formed” by natural objects, in a way that foreshadows what he later calls our “ethical drive” (sittlicher Trieb) to unite with others, both cooperatively and reciprocally, in rational community. (shrink)

In this article we examine gender differences in nonverbal expressiveness, with a particular focus on crying and smiling. We show that women cry and smile more as well as show more facial expressiveness in general, but that the size of this gender difference varies with the social and emotional context. We interpret this variation within a contextual framework (see also Brody & Hall, 2008; Deaux & Major, 1987; LaFrance, Hecht, & Paluck, 2003). More specifically, we distinguish three factors that predict (...) the size of gender differences in emotional expressiveness: gender-specific norms, social role and situational constraints, and emotional intensity. These factors interact in different ways for smiling and crying. (shrink)

This essay argues that scientific progress in STEM areas and US national biosecurity are best achieved when US scientists self-regulate, work to influence the lawmaking process at every stage of their career, and welcome or even initiate interactions with the public. Events that draw negative public attention drive laws because laws are proposed by elected representatives of the public. Laws are therefore reactive in nature, as are regulations promulgated by agencies that implement these laws. Laws and regulations are difficult (...) and time-consuming to change.While scientists provide testimony and serve on expert panels that produce reports to Congress, only a very few... (shrink)

_Clinical Interaction and the Analysis of Meaning_ evinces a therapeutic vitality all too rare in works of theory. Rather than fleeing from the insights of other disciplines, Dorpat and Miller discover in recent research confirmation of the possibilities of psychoanalytic treatment. In Section I, "Critique of Classical Theory," Dorpat proposes a radical revision of the notion of primary process consonant with contemporary cognitive science. Such a revised conception not only enlarges our understanding of the analytic process; it also provides (...) analysis with a conceptual language that can articulate meaningful connections with a growing body of empirical research about the development and nature of human cognition. In Section II, "Interactional Theory," Miller reverses the direction of inquiry. He begins with the literature on cognitive development and functioning, and proceeds to mine it for concepts relevant to the clinical process. He shows how a revised understanding of the operation of cognition and affect can impart new meaning to basic clinical concepts such as resistance, transference, and level of psychopathology. In Section III, "Applications and Exemplifications," Dorpat concludes this exemplary collaboration by exploring select topics from the standpoint of his and Miller's new psychoanalytic theory. At the heart of the authors' endeavor it "meaning analysis," a concept that integrates an up-to-date model of human information processing with the traditional goals of psychoanalysis. The patient approaches the clinical encounter, they argue, with cognitive-affective schemas that are the accumulatice product of his life experience to date; the manifold meanings ascribed to the clinical interaction must be understood as the product of these schemas rather than as distortions deriving from unconscious, drive-related fantasies. The therapist's goal is to make the patient's meaning-making conscious and thus available for introspection. (shrink)

Rom Harré has recently proposed that there is a difference between the driving force behind the early and the later Wittgenstein. According to Harré, in the early work, the major inspiration came from science, while, in the later, it came from religion. I show that only Harré’s first proposal is fully justified. In section one of my paper, I examine the picture theory, the theory of truth-functions, the meaning of propositions, and Tractatus §6.3. In section two, about the Philosophical Investigations, (...) I show that Harré is misleading. In a first step, I argue that science plays the same role in this later work as in the Tractatus, namely the role of source of inspiration. In a second step, I show that science plays also the role of a contrast against which the rich world of meaning can be discerned. I examine this contrastive role not only as regards religion, but also as regards psychology, and as regards the repercussions of Wittgenstein’s later work on science-studies. My final proposal is that the distinction between science as source of inspiration and science as a contrast goes beyond Wittgenstein: it characterises much twentieth century philosophical work in this area. (shrink)

In animals, nervous systems regulate the ingestion of food and water in a manner that reflects internal metabolic need. While the coordination of these two ingestive behaviors is essential for homeostasis, it has been unclear how internal signals of hunger and thirst interact to effectively coordinate food and water ingestion. In the last year, work in insects and mammals has begun to elucidate some of these interactions. As reviewed here, these studies have identified novel molecular and neural mechanisms that coordinate (...) the regulation of food and water ingestion behaviors. These mechanisms include peptide signals that modulate neural circuits for both thirst and hunger, neurons that regulate both food and water ingestion, and neurons that integrate sensory information about both food and water in the external world. These studies argue that a deeper understanding of hunger and thirst will require closer examination of how these two biological drives interact. (shrink)

Sociocultural developmental psychology can drive new directions in gadgetry science. We use autobiographical memory, a compound capacity incorporating episodic memory, as a case study. Autobiographical memory emerges late in development, supported by interactions with parents. Intervention research highlights the causal influence of these interactions, whereas cross-cultural research demonstrates culturally determined diversity. Different patterns of inheritance are discussed.

Top-down synthetic biology makes partly synthetic cells by redesigning simple natural forms of life, and bottom-up synthetic biology aims to make fully synthetic cells using only entirely nonliving components. Within synthetic biology the notions of complexity and emergence are quite controversial, but the imprecision of key notions makes the discussion inconclusive. I employ a precise notion of weak emergent property, which is a robust characteristic of the behavior of complex bottom-up causal webs, where a complex causal web is one that (...) is incompressible and its behavior cannot be derived except by crawling through all of the gory details of the interactions in the web. The central thesis of this article is that synthetic biology centrally is the activity of engineering the desired weak emergent properties of synthetic cells. Synthetic biology has many different ways to engineer desired weak emergent properties of synthetic cells, including Edisonian trial and error, standardized parts, refactoring, and reprogramming synthetic genomes. The article ends by noting two philosophical consequences of engineering weak emergence. One is epistemological: synthesis is crucial for discovering weak emergent properties. The other is metaphysical: simple life forms are nothing but complex chemical mechanisms. (shrink)

A 90-year-old man is diagnosed with early dementia. There are concerns about whether he is still fit to drive his car safely, but he is determined to continue driving. In this case, the clinician finds that this decision on fitness to drive is essentially evaluative and normative. Given the conflict of interests involved, how should the clinician attempt to manage this challenging ethical dilemma? This increasingly common clinical ethics scenario warrants further attention. After presenting the case, this analysis (...) will consider the relevant issues in three dimensions: an ethical dilemma, a clinician–patient interaction, and a broader context. This analysis provides a potential framework for clinicians making decisions on fitness to drive in early dementia. (shrink)

The effect of recent experience on current behavior has been studied extensively in simple laboratory tasks. We explore the nature of sequential effects in the more naturalistic setting of automobile driving. Driving is a safety-critical task in which delayed response times may have severe consequences. Using a realistic driving simulator, we find significant sequential effects in pedal-press response times that depend on the history of recent stimuli and responses. Response times are slowed up to 100 ms in particular cases, a (...) delay that has dangerous practical consequences. Further, we observe a significant number of history-related pedal misapplications, which have recently been noted as a cause for concern in the automotive safety community. By anticipating these consequences of sequential context, driver assistance systems could mitigate the effects of performance degradations and thus critically improve driver safety. (shrink)

This paper intends to reveal the essential value of interactive media by fully understanding the complex interactive mechanism of human experience. Following Cartesian dualistic thought, interactive technology has primarily been utilized as a physical control device. It hasn’t sufficiently explored its gigantic potential as a true interactive medium. Interactive technology reflects our desire to interact with someone or something. Historically, human desire for interaction has been continuously manifested from the day of primitive ritual to contemporary cyberspace. Our interactive routines (...) have continued, from micro to macro scale, in order to confirm our existence in every day life. This universal repetitive pattern of human activity is ‘the ritual’. It is ritual because it is the archetypes of cycles driven by human instinct, regardless of their cultural and historical period. In this paper, I am defining ‘the form of ritual’, to explain the fundamental human process of interaction and becoming, and furthermore, to find the imperative potential of interactive media. The form of ritual will be explained in detail, with agent, driving force, process and by-product, taking reference from Korean shaman ritual, Yin/Yang process and Alfred North Whitehead’s process philosophy. My virtual puppetry with spiralling interaction, ‘Yong-Shin-Gud’ (calling-dragon-spirit), will be introduced as an art example to carry out the ritual. Interactive technology is an ongoing expression of human desire. Its essential value would be found in understanding human beings, nature and cosmos. Revealing its hidden essence, historical presence and spiritual value will be the next paradigm of interactive art practice. (shrink)

With the global pandemic of COVID-19, it has been striking psychological burdens on individuals. Under this background, more and more people get wellbeing by watching live broadcasts. However, the psychological mechanism behind this phenomenon is still a black box. This study finds that when people watch a live broadcast and interact with anchors and other people, an interaction ritual chain is formed, and emotional energy is generated, thus making people experience and understand the meaning of the live interaction (...) ritual chains. Under the effect of the meaning transfer model, people will generate wellbeing. Specifically, the basic meaning of live interaction drives people’s generation of wellbeing. The meanings of self-participation, self-display, self-concept, and self-renewal play a role in mediation in enhancing people’s wellbeing with the basic meaning of live broadcast interaction. (shrink)

This essay contends that reality is a creative evolutionary process by which the virtual is transformed into the actual and argues that our critical conception of realism in literature needs to be altered to reflect this purposive and progressive living reality in contrast to the static and dead actuality assumed by the conventional notion of realism as mimesis. Realist fiction writers who are profound creators have strategically employed metaphysically dipolar and ethically earnest literary genres in tandem with mimetic realism, resulting (...) in complexly interactive alternative and prophetic realisms that function as catalytic agents for progressive change in our world. (shrink)

This research focuses on the driving forces of technology development and the interactive relationships between technology and the factors that promote economic development and social progress. It aims at presenting a basic theory for sustainable development, as well as a foundation for decision-makers for drawing up an integrative strategy. As such it is an attempt at how to create harmonious relations between human progress, technology, economy, and society.

In the current pandemic situation, psychological science is increasingly considered by public health policy. Empathy is mainly recognized as a crucial drive for prosocial behavior. However, this rich body of evidence still lacks visibility and implementation. Effective social programs are needed, and little is known about how to elicit empathetic drives. The paper gives first a clear foundation to the role of empathy during stressful events. It provides then a comprehensive overview of innovative interventions triggering empathic response in the (...) public such as fiction, film, and theater. Moreover, it integrates interactive ways of sharing personal views that could elicit empathetic feelings in different people. Advances deriving from this perspective could be of significant public interest in the current and future health crises and help authorities develop innovative social programs, which should be the focus of further scientific inquiry. (shrink)

SNAREs (soluble N‐ethylmaleimide‐sensitive factor attachment protein receptors) are a large family of proteins that are present on all organelles involved in intracellular vesicle trafficking and secretion. The interaction of complementary SNAREs found on opposing membranes presents an attractive lock‐and‐key mechanism, which may underlie the specificity of vesicle trafficking. Moreover, formation of the tight complex between a vesicle membrane SNARE and corresponding target membrane SNAREs could drive membrane fusion. In synapses, this tight complex, also referred to as the synaptic (...) core complex, is essential for neurotransmitter release. However, recent observations in knockout mice lacking major synaptic SNAREs challenge the prevailing notion on the executive role of these proteins in fusion and open up several questions about their exact role(s) in neurotransmitter release. Persistence of a form of regulated neurotransmitter release in these mutant mice also raises the possibility that other cognate or non‐cognate SNAREs may partially compensate for the loss of a particular SNARE. Future analysis of SNARE function in central synapses will also have implications for the role of these molecules in other vesicle trafficking events such as endocytosis and vesicle replenishment. Such analysis can provide a molecular basis for synaptic processes including certain forms of short‐term synaptic plasticity. BioEssays 24:926–936, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

This paper is concerned with the outer exponential synchronization of the drive-response complex dynamical networks subject to time-varying delays. The dynamics of nodes is complex valued, the interactions among of the nodes are directed, and the two coupling matrices in the drive system and the response system are also different. The intermittent pinning control is proposed to achieve outer exponential synchronization in the aperiodical way. Some novel sufficient conditions are derived to guarantee outer exponential synchronization of the considered (...) complex-valued complex networks by using the Lyapunov functional method. Finally, two numerical examples are presented to illustrate the effectiveness of the proposed control protocols. (shrink)

Charles Darwin remarked that “males, with their superior strength, pugnacity, armaments, unwieldly passion and love songs, are almost always the more active and most often, the initiators of sexual interactions”.1 Here, we propose that such male sex drive directly impacts the genome by leading to its progressive masculinization—genes that possess sex-specific effects on male fitness accumulate to a much greater extent and are generally more diverged.2,3 The larger proportion of male versus female fitness modifiers in combination with stronger sexual (...) selection may generate evolutionary signatures such as a greater sensitivity to male sterility4 and a paucity of X-linked male-specific genes.5-8 Male sex-drive theory complements the female-choice theory of sexual selection and allows for the genetic variation of costly sexual traits to be continuously replenished. BioEssays 27: 518–525, 2005. © 2005 Wiley periodicals, Inc. (shrink)

This article critically examines the relations between epistemics in conversation analysis and linguistic and cognitivist conceptions of communicative interaction that emphasize information and information transfer. The epistemic program adheres to the focus on recorded instances of talk-in-interaction that is characteristic of CA, explicitly identifies its theoretical origins with ethnomethodology, and points to implications of its research for the social distribution of knowledge. However, despite such affiliations with CA and ethnomethodology, the EP is cognitivist in the way it emphasizes (...) information exchange as an underlying, extrasituational ‘driver’ in social interaction. To document how the EP draws upon cognitivist conceptions of information and knowledge, we review examples from the corpus of transcripts analyzed in key publications on epistemics. Our re-analysis casts doubt upon the way EP analysis invokes an underlying order that supposedly drives the evident sequential organization of those transcripts. (shrink)

With the existing research available on negative and malevolent creativity, this paper proposes a more narrowly defined concept: the bi-directional relationship between negative and malevolent creative thinking, which is intended to clarify the way forward for research in the area of negative and malevolent creativity. This paper uses qualitative research to identify and correlate an individual's concept of negative and malevolent creativity and uses a Inductive reasoning methodology to outline a preliminary theory. Following this, the preliminary theory was returned to (...) the primary sources for validation, continuous optimization, and presentation. To better demonstrate the bidirectional linkage mechanism of thinking between the two types, this paper constructed a model to describe the relationships between the variables. This study concludes that negative creative thinking is a kind of native thinking based on personal interests that are developed to emphasize the benefits of an individual's interests, while malevolent creative thinking is a kind of native thinking based on the value-added of personal interests and is deliberately harmful. Both types of thinking share a value orientation, environmental stimulation, and subjective motivation. However, they differ in terms of value goals, ways of thinking, and the scale of the subject. It is concluded from the intrinsic thinking logic of individual thinking as well as the temporal dimension of the individual creative process that value-added and intentions to exploit others are factors that drive the transformation of negative creative thinking into malevolent creative thinking, and personal intention is a vital factor for establishing a linkage between negative and malevolent creative thinking. (shrink)

In the context of health care the aim of the article is to bring another meaning to the concept “need” that goes beyond the human activity; the drive to satisfy needs. Another meaning incorporates an ethical and existential nature of life phenomena. An example from empirical research on living with a chronic disease as seen from the patient’s point of view provides the basis for arguing another meaning of the concept “need”. The meanings and nuances in the life phenomena (...) of hope, doubt and life courage are exemplified in qualitative interviews with chronic sufferers. A combination of empirical research and Danish life philosophy. Research has shown that the interaction between the professional health care provider and the patient and family may lead to a more or less unconscious and inappropriate administration of power. Research also indicates that by overlooking or ignoring the existential qualities in human life and suffering, the professional health care provider may deprive the patient and family of their room for action. To add a deeper understanding of the existential meaning of being a person with an illness, the article shows the different human dimensions concerning life phenomena and needs. Developing sensitive, situation-specific attention offers a response to the challenge faced by health care providers in collaboration with the patient: How can we open our eyes to the most significant features of the situation which arise on the onset of illness. (shrink)

Drawing on the transactional model of stress and leader-member exchange (LMX) theory, we examine the role of performance pressure in relation to unethical pro-organizational behavior (UPB). We propose that (1) employee perceived performance pressure and LMX interact to increase employees’ willingness to engage in UPB, and (2) employees’ threat appraisal mediates this interaction effect. The results from two studies based on samples of employees in the United States and China supported our theoretical model. We found that LMX moderated the (...) relation between performance pressure and the willingness to engage in UPB, such that the relation was stronger when LMX was high (Study 1). Moreover, the conditional indirect effect (i.e., performance pressure on UPB through threat appraisal with LMX as a moderator at the first stage) was also supported (Study 2). These findings highlight the role of performance pressure and LMX in inducing unethical work behaviors that are aimed at benefiting the organization (i.e., UPB). Theoretical and managerial implications are also discussed. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Videogames and Interactive FictionGrant TavinorIIn the third-person crime simulator Grand Theft Auto 3, the fictional performing of all sorts of criminal nuisance is a possibility. (Squeamish readers, or those that are adamant videogames are playing a decisive role in the moral degeneration of modern society might want to turn away now!) Here is one possibility for players of the game: while driving around in the rundown red-light district of (...) Portland Island, try stopping beside one of the women dressed in leather dresses and knee-high stockings who say things like "Have you ever been down south?" The fictional woman will bend down to the car window and eventually hop in. Now drive to a secluded area, stop the car, and wait. What happens? The car begins to rock up and down, slowly at first, and then more quickly, squeaking all the while. As it does, your health meter increases and the cash meter decreases. Eventually, after the car has stopped rocking, the prostitute exits and walks away. This is all obviously of questionable taste. But the really horrible part is that it is possible to mug the prostitute and take back your money!Though I am reluctant to tell you this, the first time I discovered the trick, I felt a sort of sadistic joy at my reprehensible behavior. Friends in the room at the time thought the whole incident hilarious; except for one who thought it extremely revolting. Perhaps now though, I feel guilty for what I did to the prostitute. (Hence my reluctance to let you know of my sinister fictional activities!) Of course, this episode raises a host of ethical questions; I will not attempt to answer them here. What I am interested in is the possibility of fictional interaction itself. The important point is that this fictive episode seems to show that it is possible in the case of videogames to feel guilty or ashamed for what one [End Page 24] does in a fictional world. But how is this possible? What does interacting with a videogame amount to that it allows for this intimate (and dubious) emotional connection?There is a wide and impressive literature in the analytic philosophy of the arts concerning the nature of fiction and the practice that surrounds it; this literature gives us an ideal theoretical basis from which to explore the topic of videogames. But also, videogames will allow us to return our attention to the theory, perhaps perceiving areas in which it can be improved, so as to become more generally applicable. I begin this paper by setting out some initial descriptive examples of the ways in which videogames are interactive fictions. After discussing an ambiguity in the notion of what it is to interact with a fiction, I deal with two prominent aspects of that interaction; that focused on fictive props, and the apparent interaction players have with fictional worlds. Next, I argue that the interactive nature of videogames alters the character of our interest in them. Rather than a focus on interpretive and sympathetic engagement with narratives, videogames involve their appreciators in an active engagement with the problem spaces or kinetic narratives of gameplay. Finally, I argue that because action and emotion are close cognitive bedfellows, and because emotion plays an important role in the psychology of fictive practice, that the emotions experienced by videogame players will be distinctive to that fictive form.IIVideogames provide their players with a variety of opportunities for interactive engagement. The last ten years have seen significant development in the extent of the fictive interactivity of videogames, especially with the advent of the "next generation" consoles such as Playstation 2 and X-Box, and the burgeoning genre of PC gaming. With the intention of providing some descriptive substance for the following theoretical discussions, in this section I present some examples of the ways in which modern videogames are interactive fictions, and how they differ to more traditional fictive forms in this respect.Many videogames involve exploring an environment. In Grand Theft Auto 3, the player, in the guise of a criminal protagonist, is able to explore the streets of Liberty City. Completing the objectives of the... (shrink)

Complex adaptation systems are the main development direction of China’s current green innovation research. New material industry is one of the key entry points to accelerate the construction of modern industrial system and promote innovation, green, and efficient development. Under the requirements of China’s current low-carbon development, China’s green innovation system is developing rapidly. Green innovation complicates traditional innovation models and their functions and improves economic development. The purpose of this paper is to study the theoretical analysis framework of applying (...) complex adaptive systems and to analyze and calculate the characteristics of the current status of green innovation systems in multiple industries in China’s manufacturing industry. Analysis is as follows. The experimental group and the control group are set for comparison, and the data are organized by applying complex adaptive system theory and data analysis methods. Experimental data show that the coordinated development of the green innovation systems in various industries in China is not balanced, with a difference of more than three times; the parameters of the various green innovation systems within the industry are unbalanced, and the difference is more than five times. The experimental results show that the green innovation subject can strategically interact by adjusting the ratio of resource allocation through the constructed green innovation system model. The green innovation system with complex adaptive system theory is conducive to the development of the green system. It can save about 23% of green innovation time and improve efficiency by about 15%, to promote the development of green innovation in China. (shrink)

Cultural routines, such as reading and writing direction (script direction), channel attention orientation. Depending on one's native language habit, attention is biased from left‐to‐right (LR) or from right‐to‐left (RL). Here, we further document this bias, as it interacts with the spatial directionality that grounds time concepts. We used a spatial cueing task to test whether script direction and the grounding of time in Portuguese (LR, Exp. 1) and Arabic (RL, Exp. 2) shape visuomotor performance in target discrimination. Temporal words (e.g., (...) tomorrow, yesterday) were presented as cues in two modalities: visual (Exp. 1–2) and auditory (Exp. 1). Gaze movement (Exp. 1) and speed of discrimination decisions (Exp. 1–2) of targets presented to the left or right sides of the screen were assessed. As predicted, the interaction between target location and time concepts was significant across both modalities and linguistic communities. Additionally, LR participants detected the target on the right side of the screen faster after a future word than the target on the left side of the screen after a past word cue. In contrast, RL participants detected the target on the left side of the screen faster when the cue word was a future word than the target on the right side of the screen cued by a past word. In both modalities, the initial eye‐gaze movement (Exp. 1) was responsive to the cue's time referent, further confirming that time orients attention. An additional bias was observed for the first fixation onset, which landed earlier on the target set that matched habitualized spatial routines. We conclude that scanning regularities are shaped by writing habits and bodily grounded categorical features. (shrink)

The most time consuming effort has been toward building a precision, servo-controlled rotary drive to turn the attractor. After discovering our Nanomotion HR1 Ultra-High-Vacuum motor was incapable of continuous operation in a vacuum environment (due to heat management issues), we were forced to redesign the system such that the motor remained in atmosphere. We are pleased with the final performance. Fig. 2.1-1A..

Starting with Houtkoop and Mazeland’s study of discourse units, and touching upon recent studies aimed at detailing unit projection in interaction, this article argues that the drive toward abstract and discrete models for units and unit projection is potentially misleading. While it has been established that to engage in talk-in-interaction, as it unfolds in real time, participants rely on projectable units, research aimed at defining units unintentionally backgrounds the contingency inherent in interaction. A central function of (...) language for collaborative action is the management of simultaneously unfolding facets of action, sound production, gesture, and grammar – produced by multiple participants. This article draws upon classic and current data analyses foregrounding linguistic/interactional practices designed to manage local contingencies. It is argued that attention to participants’ regular methods for managing and exploiting contingencies be incorporated from the outset in our descriptions of language and the nature of unit building in interaction. (shrink)

Complex work in teams requires coordination across team members and their technology as well as the ability to change and adapt over time to achieve effective performance. To support such complex interactions, recent efforts have worked toward the design of adaptive human-autonomy teaming systems that can provide feedback in or near real time to achieve the desired individual or team results. However, while significant advancements have been made to better model and understand the dynamics of team interaction and its (...) relationship with task performance, appropriate measures of team coordination and computational methods to detect changes in coordination have not yet been widely investigated. Having the capacity to measure coordination in real time is quite promising as it provides the opportunity to provide adaptive feedback that may influence and regulate teams’ coordination patterns and, ultimately, drive effective team performance. A critical requirement to reach this potential is having the theoretical and empirical foundation from which to do so. Therefore, the first goal of the paper is to review approaches to coordination dynamics, identify current research gaps, and draw insights from other areas, such as social interaction, relationship science, and psychotherapy. The second goal is to collate extant work on feedback and advance ideas for adaptive feedback systems that have potential to influence coordination in a way that can enhance the effectiveness of team interactions. In addressing these two goals, this work lays the foundation as well as plans for the future of human-autonomy teams that augment team interactions using coordination-based measures. (shrink)

Complex work in teams requires coordination across team members and their technology as well as the ability to change and adapt over time to achieve effective performance. To support such complex interactions, recent efforts have worked toward the design of adaptive human-autonomy teaming systems that can provide feedback in or near real time to achieve the desired individual or team results. However, while significant advancements have been made to better model and understand the dynamics of team interaction and its (...) relationship with task performance, appropriate measures of team coordination and computational methods to detect changes in coordination have not yet been widely investigated. Having the capacity to measure coordination in real time is quite promising as it provides the opportunity to provide adaptive feedback that may influence and regulate teams’ coordination patterns and, ultimately, drive effective team performance. A critical requirement to reach this potential is having the theoretical and empirical foundation from which to do so. Therefore, the first goal of the paper is to review approaches to coordination dynamics, identify current research gaps, and draw insights from other areas, such as social interaction, relationship science, and psychotherapy. The second goal is to collate extant work on feedback and advance ideas for adaptive feedback systems that have potential to influence coordination in a way that can enhance the effectiveness of team interactions. In addressing these two goals, this work lays the foundation as well as plans for the future of human-autonomy teams that augment team interactions using coordination-based measures. (shrink)

Although the field of psychiatry has witnessed the proliferation of studies on Gene x Environment (GxE) interactions, still limited is the knowledge we possess of GxE interactions regarding developmental disorders. In this perspective paper, we discuss why GxE interaction studies are needed to broaden our knowledge of developmental disorders. We also discuss the different roles of hazardous versus self-generated environmental factors and how these types of factors may differentially engage with an individual’s genetic background in predicting a resulting phenotype. (...) Then, we present exemplar studies that highlight the role of GxE in predicting atypical developmental trajectories as well as provide insight regarding treatment outcomes. Supported by these examples, we explicate the need to move beyond merely examining statistical interactions between genes and the environment, and to investigate specific genetic susceptibility and environmental contexts that drive developmental disorders. We propose that further parsing of genetic and environmental components is required to fully understand the unique contribution of each factor to the etiology of developmental disorders. Finally, with a greater appreciation of the complexities of GxE interaction, this discussion will converge upon the potential implications for clinical and translational research. (shrink)

Many conserved eukaryotic traits, including apoptosis, two sexes, speciation and ageing, can be causally linked to a bioenergetic requirement for mitochondrial genes. Mitochondrial genes encode proteins involved in cell respiration, which interact closely with proteins encoded by nuclear genes. Functional respiration requires the coadaptation of mitochondrial and nuclear genes, despite divergent tempi and modes of evolution. Free‐radical signals emerge directly from the biophysics of mosaic respiratory chains encoded by two genomes prone to mismatch, with apoptosis being the default penalty for (...) compromised respiration. Selection for genomic matching is facilitated by two sexes, and optimizes fitness, adaptability and fertility in youth. Mismatches cause infertility, low fitness, hybrid breakdown, and potentially speciation. The dynamics of selection for mitonuclear function optimize fitness over generations, but the same selective processes also operate within generations, driving ageing and age‐related diseases. This coherent view of eukaryotic energetics offers striking insights into infertility and age‐related diseases. (shrink)

Self-driving cars promise solutions to some of the hazards of human driving but there are important questions about the safety of these new technologies. This paper takes a qualitative social science approach to the question ‘how safe is safe enough?’ Drawing on 50 interviews with people developing and researching self-driving cars, I describe two dominant narratives of safety. The first, safety-in-numbers, sees safety as a self-evident property of the technology and offers metrics in an attempt to reassure the public. The (...) second approach, safety-by-design, starts with the challenge of safety assurance and sees the technology as intrinsically problematic. The first approach is concerned only with performance—what a self-driving system does. The second is also concerned with why systems do what they do and how they should be tested. Using insights from workshops with members of the public, I introduce a further concern that will define trustworthy self-driving cars: the intended and perceived purposes of a system. Engineers’ safety assurances will have their credibility tested in public. ‘How safe is safe enough?’ prompts further questions: ‘safe enough for what?’ and ‘safe enough for whom?’. (shrink)

Much of the debate on the ethics of self-driving cars has revolved around trolley scenarios. This paper instead takes up the political or institutional question of who should decide how a self-driving car drives. Specifically, this paper is on the question of whether and why passengers should be able to control how their car drives. The paper reviews existing arguments—those for passenger ethics settings and for mandatory ethics settings respectively—and argues that they fail. Although the arguments are not successful, they (...) serve as the basis to formulate desiderata that any approach to regulating the driving behavior of self-driving cars ought to fulfill. The paper then proposes one way of designing passenger ethics settings that meets these desiderata. (shrink)

The purpose of this article is to present a new distributed interactive career decision-making framework in which person and context together determine the development of a sustainable career. We build upon recent theories from two disciplines: decision theory and career theory. Our new conceptual framework incorporates distributed stakeholders into the career decision-making process and suggests that individuals make decisions through a system of distributed agency, in which they interact with their context to make each career decision, at varying levels of (...) participation, from proactive to reactive. We focus on two key career decision-making drivers originating from the person, and two key drivers from the career context. This manuscript challenges the individual-driven approach to career development, and instead proposes that a process of distributed career decision-making takes place between each person and the various stakeholders, both individual and institutional, that also drive their career. Career seekers and counselors can use this framework to supplement an individual-focused approach and incorporate the role of distributed decision-makers in sustaining an individual’s career. Empirical research is needed to explore and test the applicability of the framework to career decisions in practice. (shrink)

The extended mind thesis (EM) asserts that some cognitive processes are (partially) composed of actions consisting of the manipulation and exploitation of environmental structures. Might some processes at the root of social cognition have a similarly extended structure? In this paper, I argue that social cognition is fundamentally an interactive form of space management—the negotiation and management of ‘‘we-space”—and that some of the expressive actions involved in the negotiation and management of we-space (gesture, touch, facial and whole-body expressions) drive (...) basic processes of interpersonal understanding and thus do genuine social-cognitive work. Social interaction is a kind of extended social cognition, driven and at least partially constituted by environmental (non-neural) scaffolding. Challenging the Theory of Mind paradigm, I draw upon research from gesture studies, developmental psychology, and work on Moebius Syndrome to support this thesis. (shrink)