The main idea of S-curve diagram is to assign different angle values to different nucleotide acid residues or to different protein amino acids, and then according to cos α j and sin α j, the values are accumulated to construct an S-curve diagram, which is in strict one-to-one correspondence with the biological sequence. In addition, the S-curve diagram proves to be without the degeneracy phenomenon, so that both the degeneracy problem represented by diagrams and the problem of visualization for biological (...) sequence data are solved. Meanwhile, a new approach to differentiate the similarity of biological sequences—the degree of similarity—is put forward on the basis of the S-curve diagram. To put it in detail, the least square approach is first adopted to obtain a straight line equation according to the S-curve diagram, then according to the distance formula of the point to the straight line, the average ratio of square sum for the distance between the S-curve and the straight line is calculated, and finally, the similarity of the biological sequences is presented by the new standard—the degree of similarity. As is shown by the experimental results, the S-curve diagram can better represent biological sequences within Cartesian coordinate system, and the mutation point of biological sequence. Thus, it turns out that the new standard—the degree of similarity is of obviously great advantage. (shrink)

本书是作者晚年在老朋友的建议下撰写的回忆录，内容涉及与他交往密切的老朋友、个人经历和治学活动，以及生活情趣等等。.

Economy is one of the major issues in the United States presidential election campaign. In order to investigate the impact of the US presidential election on the economy, this paper first constructs an analysis model of the economic impact on the United States based on stepwise regression and principal component analysis to analyze the focus of different candidates’ attention on the economic issues and its possible impact on the US economy in the election year and after the election; secondly, a (...) Chinese economic impact analysis model based on factor analysis and machine learning logistic regression was constructed to analyze the impact of the US presidential election on the Chinese economy. At the same time, the future economic development of the United States and China based on the time series prediction model is forecast and analyzed, respectively. Finally, the countermeasures and policy suggestions on China’s related economic development are put forward. (shrink)

BackgroundIn the early days of COVID-19 outbreak, the normally orderly health system was severely challenged by large numbers of feverish patients and shortage of healthcare workers. The outbreak played a harmful role in the mental health of these healthcare workers.ObjectiveWe aim to assess the prevalence of moderate or severe anxiety and depression symptoms of healthcare workers in different regions during COVID-19 disaster and identify the potential risk factors.MethodsWe did a cross-sectional study on ADS of healthcare workers in epicenter-Hubei province and (...) regions in lower epidemic-other provinces by questionnaire online. The data of ADS, the demographic characteristics, occupational exposure, physical condition, family situation, and coping styles were collected and analyzed.ResultsA total of 24.68% of the respondents had experienced moderate or severe ADS. Moderate or severe ADSs were in a higher prevalence in Hubei than other provinces. Suspicious symptoms on their own and in family members were independent risk factors of moderate or severe ADS of all health workers. Working on the frontline was the independent risk factor for participants in Hubei province, whereas quarantine was the independent risk factor for those in other provinces. Moreover, among all participants, those with negative coping style were more than four times more likely to have moderate or severe ADS than those with positive coping style.ConclusionModerate or severe ADSs were in a higher prevalence in healthcare workers of Hubei province during COVID-19 outbreak. The coping style may have major impact on ADS in such situation. (shrink)

Background and ObjectiveThere is a paucity of research that has explored “False Alarm” mechanisms. In order to remedy this deficiency in knowledge, the present study used event-related potential technology to reveal the mechanisms underlying False Alarm in response to fear stimuli.MethodsThis study selected snakes as experimental materials and the “oddball paradigm” was used to simulate the conditions of False Alarm. The mechanism underlying False Alarm was revealed by comparing cognitive processing similarities and differences between real snakes and toy snakes.ResultsEvent-related potential (...) findings demonstrated that there was no significant difference between N1 and P2 components induced by real and toy snakes in the early processing stage. Compared with toy snakes, real snakes induced smaller N2 amplitude, larger P3 amplitude, and a shorter P3 latency at the late processing stage. The results of brain topographic mapping analysis showed that the brain regions activated by a real or toy snake were basically the same within the time windows of 110–150 and 220–270 ms, respectively. In the time window of 300–360 and 400–500 ms, the degree of brain regions activation with a real snake was significantly greater than that induced by a toy snake.ConclusionFalse Alarm is caused by the brain’s inability to distinguish, in the early stage of cognitive processing, stimulus objects with similar appearances. When the brain is able to distinguish the differences between different stimulus objects in the late stage of cognitive processing, False Alarm disappears. (shrink)

Developing World Bioethics, Volume 22, Issue 3, Page 170-178, September 2022.

Due to the close relationship among intrinsic/extrinsic motivation, regulatory focus, and creativity revealed by previous literature, intrinsic/extrinsic motivation may play a mediating role between regulatory focus and creativity. Therefore, the present study aimed to investigate the relationship between regulatory focus and creativity by combining intrinsic/extrinsic motivation. In this study, senior high school students completed the Regulatory Focus Questionnaire, the Working Preference Inventory, the Williams Creativity Assessment Packet, and the Kirton Adaption–Innovation Inventory. The correlation analysis showed that both promotion and prevention (...) focus positively correlated with intrinsic motivation; intrinsic motivation and promotion focus positively correlated with creativity personality and innovative-adaptive cognitive style; and extrinsic motivation and prevention focus negatively correlated with innovative–adaptive cognitive style. Furthermore, a path model showed that promotion focus positively predicted creativity through the mediation of intrinsic motivation. In general, our study suggests that intrinsic motivation plays a mediating role between promotion focus and creativity. Our results complement those of previous studies and serve as inspiration for the cultivation of creativity in classroom or enterprise settings. (shrink)

Pain has not only sensory, but also emotional and cognitive, components. Some studies have explored the effect of pain on time perception, but the results remain controversial. Whether individual pain-related emotional and cognitive factors play roles in this process should also be explored. In this study, we investigated the effect of electrical stimulation–induced pain on interval timing using a temporal bisection task. During each task session, subjects received one of five types of stimulation randomly: no stimulus and 100 and 300 (...) ms of non-painful and painful stimulation. Pain-related emotional and cognitive factors were measured using a series of questionnaires. The proportion of “long” judgments of a 1,200-ms visual stimulus duration was significantly smaller with 300 ms painful stimulation than with no stimulus and 100 ms and 300 ms non-painful stimulation. The point of subjective equality did not differ among sessions, but the average Weber fraction was higher for painful sessions than for no-stimulus session. The pain fear score correlated positively with the PSE under 100 ms non-painful and painful and 300 ms painful stimulation. Pain catastrophizing and pain anxiety scores correlated significantly with the WF under no stimulus and 100 ms non-painful stimulation, respectively. These results suggest that electrical stimulation–induced pain affects temporal sensitivity, and that pain-related emotional and cognitive factors are associated with the processing of time perception. (shrink)

Electroacupuncture (EA) and electroconvulsive therapy (ECT) are often used in the management of schizophrenia. This study sought to determine whether additional EA and ECT could augment antipsychotic response and reduce related side effects. In this retrospective controlled study, 287 hospitalized schizophrenic patients who received antipsychotics (controls, n = 50) alone or combined with EA (n = 101), ECT (n = 55) or both (EA+ECT, n = 81) were identified. EA and ECT were conducted for 5 and 3 sessions per week, (...) respectively, with a maximum of 12 sessions for ECT during hospitalization. The Scale for the Assessment of Positive Symptoms (SAPS) and Scale for the Assessment of Negative Symptoms (SANS) were used to assess the severity of psychotic symptoms. Clinical response on SAPS and SANS, weight gain, and adverse events were compared. Survival analysis revealed that the ECT and EA+ECT groups had markedly greater clinical response rate than controls on SAPS [72.7% and 90.1% vs. 64.0%; relative risk (RR), 1.974 and 2.628, respectively, P ≤ 0.004] and on SANS (67.3% and 70.4% vs. 42.0%; RR, 1.951 and 2.009, respectively, P ≤ 0.015). A significantly greater response rate on SANS than controls was also observed in the EA group (64.4% versus 42.0%; RR = 1.938, P = 0.008). EA-containing regimens remarkably reduced weight gain and incidences of headache, insomnia, dry mouth, and electrocardiographic abnormalities. These results suggest that EA and ECT can serve as additional treatment for enhancing antipsychotic response and reduce the side effects in hospitalized patients with schizophrenia. (shrink)

Throughout the COVID-19 pandemic, shortages of scarce healthcare resources consistently presented significant moral and practical challenges. While the importance of vaccines as a key pharmaceutical intervention to stem pandemic scarcity was widely publicized, a sizable proportion of the population chose not to vaccinate. In response, some have defended the use of vaccination status as a criterion for the allocation of scarce medical resources. In this paper, we critically interpret this burgeoning literature, and describe a framework for thinking about vaccine-sensitive resource (...) allocation using the values of responsibility, reciprocity, and justice. Although our aim here is not to defend a single view of vaccine-sensitive resource allocation, we believe that attending critically with the diversity of arguments in favor (and against) vaccine-sensitivity reveals a number of questions that a vaccine-sensitive approach to allocation should answer in future pandemics. (shrink)

These essays engage Jin Y. Park’s recent translation of the work of Kim Iryŏp, a Buddhist nun and public intellectual in early twentieth-century Korea. Park’s translation of Iryŏp’s Reflections of a Zen Buddhist Nun was the subject of two book panels at recent conferences: the first a plenary session at the annual meeting of the Society for Asian and Comparative Philosophy and the second at the Eastern Division of the American Philosophical Association on a group program session sponsored by the (...) International Society for Buddhist Philosophy. This exchange also includes a response from Park. (shrink)

This study centers on a valuable specimen of the early vernacular Chinese novel, San Sui pingyao zhuan, to explore dynamic possibilities at the formative stage of the Chinese novel. Close inspection of the physical aspects of the extant edition of the work suggests it is a reprint bearing traces of multiple earlier editions. The analysis of the obscure chuanqi play Si xi ji shows that the story tradition of “Three Sui quelling the rebels” already existed in the mid-sixteenth century. San (...) Sui pingyao zhuan shares much common ground with early zaju drama, fifteenth-century cihua (chantefables), and pinghua (historical novels). Linking this novel with other early examples of popular literature that preceded or were contemporaneous with it, my study deepens our understanding of the formation of the early vernacular novel as well as the world of popular literature in which the novel was situated. (shrink)

With the development of information technology and the Internet of Things, the distance between people has decreased. This has brought great convenience to people’s lives, but it has also greatly changed human life. Video games and short videos have become dominant forms of entertainment, significantly influencing children's attention and time allocation. Children should be learning and developing, but entertainment that primarily focuses on superficial engagement and instant gratification have invaded children’s lives, making it difficult for them to think deeply. This (...) has resulted in many social problems. As an emerging discipline, philosophy for children (P4C) invites us to investigate how to improve children’s mental lives, allowing them to engage in independent thinking and judgment in the era of the decline of critical thinking skills and reflective capacities. This paper introduces the origin of P4C, explores its educational principles and methodologies, and presents two case studies illustrating its application in fostering collaborative learning with children in a hyper-connected society, thus illustrating the potential of P4C in addressing societal challenges arising from technological development, including issues like existential meaninglessness, depression, social isolation, and excessive gaming. (shrink)

Han Fei was a central figure in Chinese Legalism, which was a leading school of thought in the Warring States period of China, and which left a huge imprint on political culture in imperial China. This article examines the complex duality of public and private interests in Han Fei’s political thought, a crucial aspect of his thinking. I argue that Han Fei adopted a sophisticated statist approach to understanding public and private interests. For Han Fei, public interests are embodied in (...) the state while private ones have dual functions. On the one hand, private interests threaten public ones by inviting corrupt material interests, personal morality, and knowledge, as well as human relationships. On the other hand, self-centered human psychology plays a dialectic role in strengthening the state. (shrink)

Two of the lead articles in this issue examine the emerging practice of organ procurement by normothermic regional perfusion (NRP) in terms of whether or not these patients are “dead” at the time t...

Let U be an initial segment of $^*{\mathbb N}$ closed under addition (such U is called a cut) with uncountable cofinality and A be a subset of U, which is the intersection of U and an internal subset of $^*{\mathbb N}$ . Suppose A has lower U-density α strictly between 0 and 3/5. We show that either there exists a standard real $\epsilon$ > 0 and there are sufficiently large x in A such that | (A+A) ∩ [0, 2x]| > (...) (10/3+ $\epsilon$ ) | A ∩ [0, x]| or A is a large subset of an arithmetic progression of difference greater than 1 or A is a large subset of the union of two arithmetic progressions with the same difference greater than 2 or A is a large subset of the union of three arithmetic progressions with the same difference greater than 4. (shrink)

本书包括:后现代性与德国解释学;后现代性与中国传统思想;后现代“帝国”的扩张;后现代理论家如是说等内容。.

本书包括“间性”的凸现——比较诗学与比较文化的多元主义与对话交往、寻找新的问题域——比较文学—比较文化的当代课题、西方与中国:二十世纪的语言论转向、西方当代作者中心论的兴起与衰落、西方当代文本中心论的 兴起与衰落等。.

Food prices are a daily concern in many households’ decision-making, especially when people want to have healthier diets. Employing Bayesian Mindsponge Framework (BMF) analytics on a dataset of 710 Indonesian citizens, we found that people from wealthier households are less likely to have concerns about food prices. However, the degree of health considerations in food consumption was found to moderate against the above association. In other words, people of higher income-based social classes may worry more about food prices if they (...) care more about the health impacts of their food choices. These findings provide more insights for policymakers on the psychological aspects of promoting the balance between finance and health in food consumption. (shrink)

Zen philosophy of language is discussed by exploring the concepts of live and dead words, involvement with meaning and involvement with words, and the three mysterious gates as they are employed in Pojo Chinul's huatou meditation. A comparison is made between the Zen use of language and Merleau-Ponty's philosophy of visibility, Julia Kristeva's idea of the semiotic and the symbolic, and Kierkegaard's concept of anxiety, in an attempt to provide a paradigm to understand the Zen Buddhist vision.

Gitik and Rinot :1771–1795, 2012) proved assuming the existence of a supercompact that it is consistent to have a strong limit cardinal \ of countable cofinality such that \, there is a very good scale at \, and \ fails along some reflecting stationary subset of \\). In this paper, we force over Gitik and Rinot’s model but with a modification of Gitik–Sharon :311, 2008) diagonal Prikry forcing to get this result for \.

Fontanella :193–207, 2014) showed that if \ is an increasing sequence of supercompacts and \, then the strong tree property holds at \. Building on a proof by Neeman, we show that the strong tree property at \ is consistent with \, where \ is singular strong limit of countable cofinality.