All of our information about the world is derived from the function of our senses, and thus they are the principal source of all our knowledge. This was recognized explicitly by early Greek philosophers, remained an important point of discussion for nineteenth‐century philosophers, and continues to be a key issue for present‐day philosophers, psychologists, and neuroscientists. It is a key issue in cognitive science because, by initiating the processes that store and evaluate information, sensory information transmission can be considered a (...) cognitive initiator. In a very real sense, who we are and how we see the world are the result of the experiences that are mediated by our sensory systems. These are some of the reasons why the study of sensory systems has occupied such a prominent place in modern cognitive neuroscience. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

Fish, S. Georgics of the mind: Bacon's philosophy and the experience of his Essays.--Brett, R. L. Thomas Hobbes.--Watt, I. Realism and the novel.--Tuveson, E. Locke and Sterne.--Kampf, L. Gibbon and Hume.--Frye, N. Blake's case against Locke.--Abrams, M. H. Mechanical and organic psychologies of literary invention.--Ryle, G. Jane Austen and the moralists.--Schneewind, J. B. Moral problems and moral philosophy in the Victorian period.--Donagan, A. Victorian philosophical prose: J. S. Mill and F. H. Bradley.--Pitcher, G. Wittgenstein, nonsense, and Lewis Carroll.--Bolgan, A. C. (...) The philosophy of F. H. Bradley and the mind and art of T. S. Eliot: an introduction.--Davie, D. Yeats, Berkeley, and Romanticism.--Ross, M. L. The mythology of friendship: D. H. Lawrence, Bertrand Russell, and "The Blind man".--Rosenbaum, S. P. The philosophical realism of Virginia Woolf.--Bibliography (p. 357-360). (shrink)

Various attempts have been made in recent years to present Christianity in such a way that no use is made of the traditional dichotomy between the ‘natural’ and the ‘supernatural’. Braithwaite, Hare, and van Buren, for instance, appear to have no use for the dichotomy; and I think that, without too much distortion, one can say the same of Bultmann, Tillich, and Robinson. I am not, however, concerned in this paper with the work of any one thinker as such, but (...) rather with a general climate of opinion. What I want to do is to examine the grounds on which it might be argued that belief in the supernatural is discredited. The issue seems to me of special importance at the present time, since, if these grounds are inadequate, programmes of reform under the general heading ‘Christianity without the supernatural’lose much of their point; if, on the other hand, the grounds are compelling, then reform of some kind is forced upon us whatever the accompanying difficulties. (shrink)

Martin Heidegger's explication of Pindar's assertion that ‘to glorify was the essence of poetry’ puts it quite well. He tells us that for Pindar the word does not derive its force from what is already complete in itself. For then man would be glorifying what is already glorious, that which already has the power to impress men. At best the word then would denote an acknowledgment or a confession of being impressed. Instead, he insists, the word denotes the power of (...) making to appear, or to extol a place. 1. (shrink)

In this paper I shall examine a variety of situations in which human agents make use of force. Section I will be concerned with the use of force in medical contexts, Section Ii with the use of force in defence of property, and Section in with the use of force in resolving international disputes. I shall argue that the boundary between what is and is not morally permissible needs to be, drawn more stringently than is commonly supposed. While agreeing that (...) in some medical contexts and in some situations where defence of property is involved the use of force may be necessary and even morally required, I shall suggest that in the absence of any suitably constituted world court the use of force in attempting to resolve international disputes creates a morally different situation. (shrink)

The key points in Meynell's argument seem to me to be as follows: It is logically absurd to say of an action or of a state of affairs that it is good unless at least some or other of the qualities w, x, y, z, etc. are present. Similarly it is logically absurd to talk of human flourishing unless some or other specifiable features are present in a person's life. The Heimler questionnaire shows us the sorts of ways in which (...) the notion of human flourishing might be ‘unpacked’, viz, in terms of satisfaction through friendship, etc. I am in full agreement with him over and I shall simply add some further comments on the notion of ‘evaluating’; but as far as is concerned I shall voice some doubts and reservations. (shrink)

T. R. Miles; IV—The “Mental” - “Physical” Dichotomy, Proceedings of the Aristotelian Society, Volume 64, Issue 1, 1 June 1964, Pages 71–84, https://doi.org/10.1.

What is sexual orientation? The contemporary consensus among philosophers is that it is a disposition. Unsurprisingly, recent debates about the metaphysics of sexual orientation are almost entirely intramural. Behavioral dispositionalists argue that sexual orientation is a disposition to behave sexually. Desire dispositionalists argue that it is a disposition to desire sexually. We argue that sexual orientation is not best understood in terms of dispositions to behave or dispositions to desire before arguing that dispositions tout court fail to illuminate sexual orientation. (...) We then introduce and defend the idea that sexual orientation is best understood in terms of categorical phenomenal properties of sexual arousal. (shrink)

Originally published in 1955. The Madhyamika philosophy is, in the author's view, the philosophy which created a revolution in Buddhism and through that in the whole range of Indian philosophy. This volume is a study of the Madhyamika philosophy in all its important aspects and is divided into three parts: Historical: this traces the origin and development of the Madhyamika philosophy. The second part concentrates on a full and critical exposition of the Madhyamika philosophy, the structure of its dialectic, its (...) conception of the Absolute and its ethics and religion. The last part of the book compares the Madhyamika with some of the well-known dialectical systems of the West (Kant, Hegel and Bradley) and undertakes a short study of the different absolutisms (Madhyamika, Vijnanavada and the Vedanta). (shrink)

We argue that abduction does not work in isolation from other inference mechanisms and illustrate this through an inference scheme designed to evaluate multiple hypotheses. We use game theory to relate the abductive system to actions that produce new information. To enable evaluation of the implications of this approach we have implemented the procedures used to calculate the impact of new information in a computer model. Experiments with this model display a number of features of collective belief-revision leading to consensus-formation, (...) such as the influence of bias and prejudice. The scheme of inferential calculations invokes a Peircian concept of ‘belief’ as the propensity to choose a particular course of action. (shrink)

This chapter contains sections titled: Hunting as the Pursuit of Wild “Life” Carnal Bonds and the Way of All Flesh Saintly Chewing and the Corruption of the Flesh The Vital Paradox: The Acceptance of Death as Affirmation of Life Notes.

While there is a history of sorts clearly evident in the Preliminaries of James Harrington's Commonwealth of Oceana, one can hardly escape noticing the model qualities of the Commonwealth as it is proposed. Accepting this apparent dualism as an obstacle, Pocock has noted that Oceana cannot be understood as utopia unless first understood as history. Others would not necessarily agree. Yet, given that Harrington located his explanation for the dissolution of the government upon the failure of the nobility to maintain (...) English arms in time of crisis, I argue that in seeking a solution he turned to a series of debates regarding the history of the contemporary alternative to those failed feudal armies, the English militia. Having identified a crisis of arms, Harrington found tactical models dealing with the organization of a militia -- both contemporary and ancient -- to be a perfect historical model for his own commowealth. Considered in this context, the utopian status of the Commonwealth's orders becomes questionable and the work appears much more historical throughout. (shrink)

Within contemporary evangelical theology, a peculiar controversy has been brewing over the past few decades with regard to the doctrine of the Trinity. A good number of prominent evangelical theologians and philosophers are rejecting the doctrine of divine processions within the eternal life of the Trinity. In William Hasker’s recent Metaphysics and the Tri-Personal God, Hasker laments this rejection and seeks to offer a defense of this doctrine. This paper shall seek to accomplish a few things. In section I, I (...) shall first set the stage for a proper understanding of the discussion. Section II will articulate the basic Trinitarian desiderata that must be satisfied by any model of the doctrine of the Trinity. This will help one understand the debate between Hasker and the procession deniers. Section III will offer an articulation of what the doctrine of divine processions teaches. Section IV will examine Hasker’s defense of the doctrine point by point. I shall argue that his defense of the doctrine of the divine processions fails. (shrink)

T. R. Miles; IV—The “Mental” - “Physical” Dichotomy, Proceedings of the Aristotelian Society, Volume 64, Issue 1, 1 June 1964, Pages 71–84, https://doi.org/10.1.

When Cicero uncovered and suppressed the Catilinarian Conspiracy as consul in 63 B.c., supporters hailed him ‘father of his country’ and proposed that he be awarded the oak crown normally given to a soldier who had saved the life of a comrade in battle . Our sources connect these honours with earlier heroes such as Romulus, Camillus and Marius, but the Elder Pliny writes as if Cicero was the first before Caesar and the Emperors to be given the title pater (...) patriae. Pliny's point may revolve around Senatorial initiative, and assuming this to be the case he really should have stressed that Cicero received the informal support of a limited number of Senators only, whereas Caesar and the Emperors were honoured by formal vote of the entire Senate. Perhaps Pliny was fooled by the prominence of those who spoke on Cicero's behalf, such as Cato, Catulus and Gellius Publicola. Opponents, on the other hand, angrily rejected calls that Cicero be recognised as the saviour of the state. In their eyes his execution of the Catilinarians marked him as a cruel tyrant. Metellus Nepos proposed Pompey's recall from the East in order to free Rome from Cicero's tyranny. Aside from echoes of patria potestas, it seems obvious that the Romans were thinking in terms of the conventional Greek antithesis between the good king who is like a father to his people and the selfish tyrant who treats his subjects as slaves. The Younger Pliny employs the same basic ideas in his Panegyricus: the cruel tyrant Domitian suppressed freedom and desired honour as a god ; the gentle Trajan is a citizen and father not a tyrant and master . Tacitus has this basic distinction in mind too. Nevertheless, as is well known, Pliny regularly addresses Trajan not as ‘father’ but as ‘master’ in Book 10 of his Letters. This was plainly an acceptable practice on the social plane, if not quite yet on the political. Augustus, Tiberius and Claudius indicated their opposition to dominus as a title for themselves, evidently for its connotations of autocracy and servitude. Domitian, damned as a tyrant, was accused of demanding to be addressed as dominus et deus. The title dominus existed from at least the first century A.d. as a common form of polite address between inferiors and superiors of free birth, not only between masters and slaves. It gradually gained acceptance as an official title of the Emperor through the second century and was advertised widely by the Severi. And yet its tone throughout this period could also be critical when understood in terms of the good king/tyrant antithesis. (shrink)

That the concepts of confirmation and requirement are very similar has recently been suggested by the discovery of four analogies between them. This conjecture is tested by comparing examples of each relation. I show that both of these relations can be "defeated" in two similar ways. But I also argue for two important dissimilarities between them: 1) when faced with certain inconsistencies, requirement suffers much more drastically than confirmation, and 2) confirmation is partiresultant in a sense in which requirement is (...) not. (shrink)

That the concepts of confirmation and requirement are very similar has recently been suggested by the discovery of four analogies between them. This conjecture is tested by comparing examples of each relation. I show that both of these relations can be "defeated" in two similar ways. But I also argue for two important dissimilarities between them: 1) when faced with certain inconsistencies, requirement suffers much more drastically than confirmation, and 2) confirmation is partiresultant in a sense in which requirement is (...) not. (shrink)

Puzzle-solving, like several other everyday activities, appears in a more sophisticated and ramified form in the realm of natural science. Improving on Thomas Kuhn's rudimentary account of puzzles in science, this paper formulates logical and functional criteria for the occurrence of scientific puzzles, and examines the two-fold nature of their solutions. Then, with the aid of erotetic logic, puzzle-posing questions are identified, their presuppositional relations to scientific theory and explanations are explored, and a new tool for history of science research (...) is developed. (shrink)

Objective: To determine if the medical record might overestimate the quality of care through false, and potentially unethical, documentation by physicians.Design: Prospective trial comparing two methods for measuring the quality of care for four common outpatient conditions: structured reports by standardised patients who presented unannounced to the physicians’ clinics, and abstraction of the medical records generated during these visits.Setting: The general medicine clinics of two veterans affairs medical centres.Participants: Twenty randomly selected physicians from among eligible second and third year internal (...) medicine residents and attending physicians.Main measurements: Explicit criteria were used to score the medical records of physicians and the reports of SPs generated during 160 visits . Individual scoring items were categorised into four domains of clinical performance: history, physical examination, treatment, and diagnosis. To determine the false positive rate, physician entries were classified as false positive , false negative, true positive, and true negative.Results: False positives were identified in the medical record for 6.4% of measured items. The false positive rate was higher for physical examination and diagnosis than for history and treatment . For individual physician subjects, the false positive rate ranged from 0.098 to 0.397.Conclusions: These data indicate that the medical record falsely overestimates the quality of important dimensions of care such as the physical examination. Though it is doubtful that most subjects in our study participated in regular, intentional falsification, we cannot exclude the possibility that false positives were in some instances intentional, and therefore fraudulent, misrepresentations. Further research is needed to explore the questions raised but incompletely answered by this research. (shrink)

Leontius of Jerusalem is considered the most accomplished of the neo-Chalcedonian theologians of the sixth century. He shows himself, in his Testimonies of the Saints, to be an ecumenical theologian attempting to convince Syrian anti-Chalcedonians that their objections to Chalcedon are baseless, since all agree, beneath their antithetical formulae, on a christology of hypostatic union. They are urged to abandon their self-important yet discredited mentor, Severus, and to see that Chalcedon had no secret agenda. Gray's edition of this important early (...) Christian treatise provides an introduction, the Greek text, and notes, together with a new translation into readable, modern English. (shrink)

To model behavioral and neural correlates of language comprehension in naturalistic environments, researchers have turned to broad‐coverage tools from natural‐language processing and machine learning. Where syntactic structure is explicitly modeled, prior work has relied predominantly on context‐free grammars (CFGs), yet such formalisms are not sufficiently expressive for human languages. Combinatory categorial grammars (CCGs) are sufficiently expressive directly compositional models of grammar with flexible constituency that affords incremental interpretation. In this work, we evaluate whether a more expressive CCG provides a better (...) model than a CFG for human neural signals collected with functional magnetic resonance imaging (fMRI) while participants listen to an audiobook story. We further test between variants of CCG that differ in how they handle optional adjuncts. These evaluations are carried out against a baseline that includes estimates of next‐word predictability from a transformer neural network language model. Such a comparison reveals unique contributions of CCG structure‐building predominantly in the left posterior temporal lobe: CCG‐derived measures offer a superior fit to neural signals compared to those derived from a CFG. These effects are spatially distinct from bilateral superior temporal effects that are unique to predictability. Neural effects for structure‐building are thus separable from predictability during naturalistic listening, and those effects are best characterized by a grammar whose expressive power is motivated on independent linguistic grounds. (shrink)

The Sovereignty of Law presents Trevor Allan's most recent and fully elaborated defence of common law constitutionalism - an account of the unwritten or non-codified constitution as a complex articulation of legal and moral principles, defining what in the British context are the requirements of the rule of law. The British constitution is conceived as a coherent set of fundamental principles of the rule of law, legislative supremacy, and separation of powers. These principles.

The figure of Myroslav Shkavrytko as an active figure and ideologist of the Ukrainian religious movement is virtually unknown to modern scholars. Also unknown are the doctrines and activities of the Holy Faith - Native Faith created by M. Shkavrytko.