BackgroundInformed consent forms for clinical research are several and variable at international, national and local levels. According to the literature, they are often unclear and poorly understood by participants. Within the H2020 project CORBEL—Coordinated Research Infrastructures Building Enduring Life-science Services—clinical researchers, researchers in ethical, social, and legal issues, experts in planning and management of clinical studies, clinicians, researchers in citizen involvement and public engagement worked together to provide a minimum set of requirements for informed consent in clinical studies.MethodsThe template (...) was based on a literature review including systematic reviews and guidelines searched on PubMed, Embase, Cochrane Library, NICE, SIGN, GIN, and Clearinghouse databases, and on comparison of templates gathered through an extensive search on the websites of research institutes, national and international agencies, and international initiatives. We discussed the draft versions step-by-step and then we referred to it as the “matrix” to underline its modular character and indicate that it allows adaptation to the context in which it will be used. The matrix was revised by representatives of two international patient groups.ResultsThe matrix covers the process of ensuring that the appropriate information, context and setting are provided so that the participant can give truly informed consent. It addresses the key topics and proposes wording on how to clarify the meaning of placebo and of non-inferiority studies, the importance of individual participants’ data sharing, and the impossibility of knowing in advance how the data might be used in future studies. Finally, it presents general suggestions on wording, format, and length of the information sheet.ConclusionsThe matrix underlines the importance of improving the process of communication, its proper conditions (space, time, setting), and addresses the participants’ lack of knowledge on how clinical research is conducted. It can be easily applied to a specific setting and could be a useful tool to identify the appropriate informed consent format for any study. The matrix is mainly intended to support multicentre interventional randomized clinical studies, but several suggestions also apply to non-interventional research. (shrink)

Lorsque la controverse sur les gaz de schiste a éclaté au Québec, les pouvoirs publics ont fait le pari de miser sur la science et les nouvelles connaissances pour refroidir le débat et construire l’acceptabilité sociale de la filière. Or, si la stratégie retenue a permis de documenter la technique de fracturation sous ses multiples aspects et d’approfondir les connaissances sur le milieu physique, biologique, économique et social ainsi que sur l’encadrement juridique, les recherches scientifiques sur la filière des (...) gaz de schiste n’ont pas calmé le jeu, tant s’en faut. Le dispositif mis en place pour piloter les études, le Comité sur l’évaluation environnementale stratégique sur les gaz de schiste, a très tôt suscité une vive opposition en raison de sa composition et de son mandat ; parallèlement, une science de contestation s’est développée à travers la mise sur pied d’un réseau de scientifiques opposés à la filière. Si bien que loin de pacifier les débats, la démarche scientifique a participé de la controverse jusqu’à la fin du processus marqué par la publication du second rapport du Bureau d’audiences publiques sur l’environnement. Le présent article propose de retracer les rapports entre science et acceptabilité sociale dans le dossier des gaz de schiste au Québec à l’échelle de la filière elle-même, mais aussi du processus décisionnel mis en place par le gouvernement pour fixer sa politique en la matière. (shrink)

This article explores Carter G. Woodson’s The Mis‐Education of the Negro in terms of its political philosophical content. It examines how Woodson’s account of the miseducation of Black people and the accordant miseducation of whites is involved in the production and reproduction of an unjust basic structure, with reference to John Rawls and Frantz Fanon. It then turns to Woodson’s critique of leadership and its relationship to miseducation, drawing on E. Franklin Frazier’s study of the Black bourgeoisie and the political (...) philosophy of Enrique Dussel. Finally, it examines miseducation as a site for the reproduction of racist knowledge production in light of the work of Anténor Firmin and examines how, for Woodson, rigor in the human sciences was essential for counteracting miseducation and serving the greater cause of liberation. (shrink)

Science in the Changing World, first published in 1933, contains a series of broadcasted presentations on the relationship between science and the development of European civilisation in the first half of the 20th century. Specifically, each talk attempts to reflect the crisis through which the world seemed to be passing at the time, and to make an analysis of those forces of transformation in science, art, economics, and social life which were associated most closely with the advent (...) of the 'scientific' century. Included among the presenters are such eminent and diverse thinkers as Julian Huxley, Bertrand Russell and Hilaire Belloc. Science at Your Service: First published in 1945, this collection of twelve BBC broadcasts focuses on the influence of science in everyday life, and demonstrates that not all science is remote and theoretical. Each speaker deals with some aspect of mid-20th century scientific advance as it related to subjects of practical importance, from textiles and tunnels to fishing and ship design. Offering a glimpse into the attitudes towards science current in the middle of the Second World War, this brief and accessible collection will be of interest to cultural historians as well as to the general science enthusiast. (shrink)

Some of the most significant policy responses to cases of fraudulent and questionable conduct by scientists have been to strengthen professionalism among scientists, whether by codes of conduct, integrity boards, or mandatory research integrity training programs. Yet there has been little systematic discussion about what professionalism in scientific research should mean. In this paper I draw on the sociology of the professions and on data comparing codes of conduct in science to those in the professions, in order to examine (...) what precisely the model of professionalism implies for scientific research. I argue that professionalism, more than any other single organizational logic, is appropriate for scientific research, and that codes of conduct for scientists should strengthen statements concerning scientific autonomy and competence, as well as the scientific service ideal. (shrink)

Georgius Trapezuntius Cretensis (or George of Trebizond) (1396-1472), an eminent humanist scholar who immigrated to Italy from Crete, is well appreciated for his translations, commentaries and treatises on philosophy, rhetoric and science. While there is a good deal of scholarship on Byzantine scholars in the Italian Renaissance, the topic of their contribution to mathematics and science in general has not to date been thoroughly addressed. This paper purports to fill this lacuna. On the basis of major evidence, I (...) will attempt to show the way Trapezuntius treated mathematics and physical sciences in order to serve his personal goals in the mid 15th century. (shrink)

L'esprit des Lumières du xvii-xviiie siècle, celui de la raison, de la science, de l'humanisme et du progrès - par opposition à l'obscurantisme, a conduit à l'émergence de connaissances scientifiques disruptives - même en ce qui concerne les fondements de la Société - et indiscutables pour quiconque fait appel à sa raison. Il a ainsi induit de nombreuses transformations dans tous les secteurs de la Société.Aujourd'hui, les technologies numériques, par l'observation de phénomènes invisibles - qui seraient impossibles sans elles (...) - ont déjà induit une multitude de pratiques perturbatrices. Comme cet effet et ses inévitables implications continuent de s'accélérer dans le futur, leur intégration dans la progression de la Société et de l'entreprise est maintenant absolument impérative.Ce livre a pour objet de faire ressortir l'intelligence de la progression de la Société ou de l'entreprise en permettant à l'intelligence du vivre ensemble (Sciences humaines), à l'intelligence des solutions (Sciences exactes) et à l'intelligence de l'artificiel (Sciences de l'ingénieur, y compris le numérique), de se relier entre elles par l'intelligence informationnelle des services. Une telle connexion est établie grâce à la science des services. Elle constitue la base des Lumières informationnelles. (shrink)

From 1687, the year when Newton published his Principia, to the Crystal Palace Exhibition of 1851, science gradually became central to Western thought and economic development. The book examines how, despite powerful opposition on the Continent, a Newtonian understanding gained acceptance and practical application.

Artificial insemination was the first conceptive technology to be widely used in agriculture. Whereas at the beginning of the twentieth century all cows in England and Wales were mated to bulls, by the end of the 1950s 60% conceived through artificial insemination. By then a national network of ‘cattle breeding centres’ brought AI within the reach of every farmer. In this paper I explore how artificial insemination, which had few supporters in the 1920s and 1930s, was transformed into an ‘indispensable’ (...) method for reproducing cattle. I discuss the factors that made organised AI possible , including changes in cultures of cattle breeding, novel State involvement in bovine reproduction, the rise of new ‘animal breeding research’ centres at Cambridge, Edinburgh and Reading universities, war preparations and central planning by the Milk Marketing Board . I go on to show that the unprecedented focus on bovine reproduction set in motion by the AI centres effectively generated new networks of reproductive research, through these the ‘biopower’ of the farm was incorporated into the clinic. The example of AI shows that by combining the history of reproductive technology in agriculture and medicine we can give a richer account of modern reproduction. (shrink)

This study aims to investigate the awareness and perception level of bioethical issues among pre-service science teachers at one of the Malaysian Education Institutions. A total of 67 respondents studying science major and science elective were involved. A questionnaire based survey with an alpha Cronbach of approximately 0.93 was used. Data were analysed using SPSS version 22. The results showed that the average awareness and perception level were =4.218±0.758 (very high level) and =3.991±0.923 (high level), respectively. (...) There was a statistically significant difference according to religion and course. Cloning showed the highest awareness level followed by organ donation, genetic modification, stem cells, abortion, gene therapy, gene screening and euthanasia. Overall, the findings indicated that pre-service science teachers were aware of the existence of bioethical issues. However, the authorities may implement bioethical issues more firmly in the future to increase pre-service science teachers’ awareness and perception level. (shrink)

The article sheds light on psychological and work science aspects of the design and utilization of service robots. An initial presentation of the characteristics of man–robot interaction is followed by a discussion of the principles of the division of functions between human beings and robots in service area work systems. The following aspects are to be considered: (1) the organisation of societal work (such as the different employment and professional profiles of service employees), (2) the work (...) tasks to be performed by humans and robots (such as handling, monitoring or decision-making tasks), (3) the possibilities and the limitations of realizing such tasks by means of information technology (depending, for example, on the motoric capabilities, perception and cognition of the robot). Consideration of these three design perspectives gives rise to criteria of usability. Current debate focuses on the (work science) principles of man–machine communication, though in future these should be supplemented with robot-specific criteria such as "motoric capabilities" or "relationship quality." The article concludes by advocating the convergence and combination of work science criteria with ideas drawn from participative design approaches in the development and utilization of service robots. (shrink)

Profit-oriented service sectors such as tourism, hospitality, and entertainment are increasingly looking at how professional service robots can be integrated into the workplace to perform socio-cognitive tasks that were previously reserved for humans. This is a work in which social and labor sciences recognize the principle role of emotions. However, the models and narratives of emotions that drive research, design, and deployment of service robots in human–robot interaction differ considerably from how emotions are framed in the sociology (...) of labor and feminist studies of service work. In this paper, we explore these tensions through the concepts of affective and emotional labor, and outline key insights these concepts offer for the design and evaluation of professional service robots. Taken together, an emphasis on interactionist approaches to emotions and on the demands of affective labor, leads us to argue that service employees are under-represented in existing studies in human–robot interaction. To address this, we outline how participatory design and value-sensitive design approaches can be applied as complimentary methodological frameworks that include service employees as vital stakeholders. (shrink)

Ecosystems services are provisions that humans derive from nature. Ecologists trying to value ecosystems have proposed five categories of these services: preserving, supporting, provisioning, regulating and cultural. While this ecosystem services framework attributes 'material' value to nature, sacred natural sites are areas of 'non-material' spiritual significance to people. Can we reconcile the material and non-material values? Ancient classical traditions recognise five elements of nature: earth, water, air, fire and ether. This commentary demonstrates that the perceived properties of these elements correspond (...) with the ecosystem services framework. Whilst the two can be reconciled, the 'elements of nature' framework is argued to be more suitable to make a case for conservation of sacred natural sites because it can be attractive to traditional societies whilst being acceptable to Western science. (shrink)

Nombre de naturalistes du XVIIIe siècle sont des clercs. Ils ont investi cette science à des fins apologétiques.

Most historians of science eagerly acknowledge that the early modern period witnessed a shift from a prevailing Aristotelian, spherical, centered conception of space to a prevailing Cartesian, rectilinear, oriented spatial framework. Indeed, this shift underlay many of the important advances for which the period is celebrated. However, historians have failed to engage the general conceptual shift, focusing instead on the particular explanatory developments that resulted. This historical lacuna can be attributed to a historiographical problem: the lack of an adequate (...) unit of analysis by which to investigate the conceptual change. Here, a philosophical argument is made for representations of space as an appropriate category of historical investigation, and methods of textual interrogation are suggested to this end. Finally, two examples, taken from Aristotle and Newton, demonstrate the feasibility and importance of this project. (shrink)

Fondée en 1928 par Magnus Hirschfeld, la Ligue Mondiale pour la Réforme Sexuelle entendait rassembler médecins et « profanes » dans le but de diffuser dans l’opinion publique les acquis de la nouvelle « science sexuelle » et d’influencer les gouvernements dans un sens progressiste, sur des questions aussi variées que le contrôle des naissances, le mariage et le divorce, l’homosexualité, la prostitution ou l’eugénisme. Très vite pourtant, elle fut déchirée entre des tendances contradictoires, et dans l’incapacité de mener (...) à bien ses objectifs, alors que la crise des années trente rendait son combat pour une nouvelle morale sexuelle rationnelle et humaniste de plus en plus utopique et que son pouvoir d’action se trouvait limité à la tenue de Congrès et à la dénonciation des lois injustes. (shrink)

We are fixated on technology and technological success, and we have no sustained or systematic approach to field-based social understanding of our adversaries' motivation, intent, will, and the dreams that drive their strategic vision, however strange those dreams and vision may seem to us.