This article explores the influence of modernity in India, within the larger framework of state-led modernity and its impact on identity and locality. The discourse on modernity has retained the common thread of transience and reflexivity as two constitutive features, both of which are taken up to explain the uncertain and provisional influence of modernity on the Indian society and identity, and the radical engagement of social movements with modernity. The article studies the complex functioning of modernity in India by (...) presenting a theoretical outline on the contested nature of the concept, with an emphasis on the discussion around reflexivity, which forms one of the core attributes for the creation of multiple and alternative modernities, by reviewing state-led modernity in India and its impact on identity formation as a consequence of the numerous and variable cultural and value systems that confront individuals and by looking at the local appropriation of contested spaces to enter into a radical, value-based engagement with global modernity. (shrink)

This volume explores Nietzsche's decisive encounter with the ancient philosopher, Epicurus. The collected essays examine many previously unexplored and underappreciated convergences, and investigate how essential Epicurus was to Nietzsche's philosophical project through two interrelated overarching themes: nature and ethics. Uncovering the nature of Nietzsche's reception of, relation to, and movement beyond Epicurus, contributors provide insights into the relationship between suffering, health and philosophy in both thinkers; Nietzsche's stylistic analysis of Epicurus; the ethics of self-cultivation in Nietzsche's Epicureanism; practices of eating (...) and thinking in Nietzsche and Epicurus; the temporality of Epicurean pleasure; the practice of the gay science, and Epicureanism and politics. The essays also provide creative comparisons with the Stoics, Hobbes, Mill, Guyau, Buddhism, and more. Nietzsche and Epicurus offers original and illuminating perspectives on Nietzsche's relation to the Hellenistic thinker, in whom Nietzsche saw the embodiment of the practice of philosophy as an art of existing. (shrink)

Two recent works will be considered that discuss Heidegger and Nietzsche in the context of the problem of overcoming metaphysics and the onto-theological tradition. A common criticism will be that these works in their attempt to retrieve a conception of religion, politics or faith beyond onto-theology and metaphysics tend to justify or idealize particular historically and culturally conditioned perspectives, which are not immune from further philosophical critique. Simon Oliai’s approach to countering the burgeoning fundamentalisms in our global age is ultimately (...) not very convincing, representing as it does, a Western, liberal, Eurocentric worldview. The author’s use of Nietzsche or Heidegger for this purpose is also not very compelling. The remainder of this review essay appraises the volume edited by Cimino and van der Heiden, which attempts to rethink faith beyond onto-theology in several interesting ways. Although meant to be a comparative study, several contributions subscribe to a general Heideggerian (or Heidegger-inspired phenomenological-hermeneutical) theoretical framework, which itself is not rigorously scrutinized. A problematic implication is that Nietzsche’s own critical and constructive views of philosophy, his critique of religion and history, and his positive appraisal of faith and divinity are not seriously considered on their own terms: they are either mostly ignored, or they are selectively interpreted through a Heideggerian lens, with the result that this volume puts forward a mostly unfavorable view of Nietzsche. Some of the conceptual moves credited to Heidegger in the volume have their equivalents in Nietzsche’s philosophy, which a comparative and evaluative study such as this one must seriously take into account by resisting the uncritical acceptance of Heidegger’s own view of Nietzsche. (shrink)

We appreciated the important commentary provided by Michelle Oberman on our paper, (CQ Vol. 6, No. 1). For the most part we agree with Oberman's analysis of the issues, but there are seven points of variance, either of conception, emphasis, or accuracy. We wish to clarify these and welcome the chance her commentary provided to offer aspects of the social situation surrounding the case we presented.

Serial analysis of gene expression (SAGE) is a powerful technique that can be used for global analysis of gene expression. Its chief advantage over other methods is that it does not require prior knowledge of the genes of interest and provides qualitative and quantitative data of potentially every transcribed sequence in a particular cell or tissue type. This is a technique of expression profiling, which permits simultaneous, comparative and quantitative analysis of gene‐specific, 9‐ to 13‐basepair sequences. These short sequences, called (...) SAGE tags, are linked together for efficient sequencing. The sequencing data are then analyzed to identify each gene expressed in the cell and the levels at which each gene is expressed. The main benefit of SAGE includes the digital output and the identification of novel genes. In this review, we present an outline of the method, various bioinformatics methods for data analysis and general applications of this important technology. BioEssays 26:916–922, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

We address Northcott’s criticism of Pearson’s correlation coefficient ‘r’ in measuring causal strength by replacing Pearson’s linear regressions by nonparametric nonlinear kernel regressions. Although new proof shows that Suppes’ intuitive causality condition is neither necessary nor sufficient, we resurrect Suppes’ probabilistic causality theory by using nonlinear tools. We use asymmetric generalized partial correlation coefficients from Vinod [2014] as our third criterion in addition to two more criteria. We aggregate the three criteria into one unanimity index, UI in [-100; 100], (...) quantifying causal strengths associated with causal paths: Xi -> Xj, Xj -> Xi, and Xi Xj. (shrink)

The goal of this article is to trace the transformations in Nietzsche's early thinking that led to the ideas published in Human, All Too Human, the first book of his mature philosophy. In contrast to his early works, in which he sides with art and philosophy in criticizing the scientific culture of his time, Nietzsche, in Human, All Too Human, hails the methodology of science as a way to overcome the metaphysical delusions of philosophy, art, and religion. However, in disagreement (...) with popular scholarly view, I show that Human, All Too Human does not represent a complete break with his earlier writings, but rather a shift in emphasis. I argue that the overall project connecting Nietzsche's early thought to Human, All Too Human is, first, the attempt to come to terms with the upheavals introduced into the cultural terrain by the Socratic turn, and second, to affirm a higher culture. (shrink)

“Ethical dilemmas…are rarely simple and stark but are, instead, multifaceted, complex, and gut wrenching for parents and care givers alike.” This is never more the case than when one must treat vulnerable babies who are not, nor ever can be competent to offer us some guidance about that treatment. The ethical problems are heightened when the parents, or the single mother, are incompetent to make decisions themselves, for example, because of drug addiction. In such cases, when the baby is premature (...) and suffering the effects of the drugs the mother has taken, and the mother herself is either no longer available for consultation or so damaged by her own addiction that she is not a reliable decisionmaker, the usual trend In the United States is to initiate treatment and continue until it is virtually certain that the infant will die. (shrink)

Paul Raimond Daniels’s Nietzsche and The Birth of Tragedy is an engaging, instructive, and clearly written study of Nietzsche’s first book. It is a particularly fine achievement given the difficulties, in terms of both style and content, that Nietzsche’s text presents to the reader. Daniels’s aim is to present BT as an ideal introduction to Nietzsche’s philosophy, and, in light of its problematizing of the relation between art and truth, to argue that BT is crucial for evaluating the aims, successes, (...) and shortcomings of Nietzsche’s later philosophy. Furthermore, Daniels presents an “affirmative” interpretation, arguing that BT champions a life-affirming worldview that finds its highest expression in... (shrink)

It frequently happens in philosophy that a philosopher, in trying to resolve a long-standing dispute between two opposing schools of thought, comes up with a schema that not only resolves the targeted dispute, but in addition necessarily imposes a residual set of regulations and norms, to which it had to subscribe in its attempt to solve the dispute, given its own presuppositions and points of departure. This residual set of norms is then viewed by the subsequent generation of thinkers, who (...) start off their philosophy from a slightly different set of presuppositions, as being superfluous to what they conceive as the real project of the previous thinker. Hence, these subsequent philosophers build their philosophy by fundamentally modifying the stance of the previous thinker, all the while acknowledging the resolution of the dispute the latter carried out in his philosophy. One can view this process of fundamental shifts in orientation as the process of transition from one revolution to another in the history of philosophy. (shrink)

Nationwide, almost 11% of women abuse drugs during their pregnancy. In some communities, these numbers are as high as 25–30%. Drug abuse is not limited to the poor or to African Americans, but is seen among affluent and white Americans as well. It is widespread, irrespective of race or social class. Annually, nearly 375,000 infants are exposed to drugs in America. Because of the terrible suffering caused by these births, and the conflicts caregivers experience in the treatment of these infants, (...) Trollope's quote is very apropos. Although caregivers have good motives in trying to rescue these babies and helping place them in a nurturing environment, despair about this objective is always close to the surface. (shrink)

We appreciated the important commentary provided by Michelle Oberman on our paper, “Discontinuing Life Support in an Infant of a Drug-Addicted Mother: Whose Decision Is It?” . For the most part we agree with Oberman's analysis of the issues, but there are seven points of variance, either of conception, emphasis, or accuracy. We wish to clarify these and welcome the chance her commentary provided to offer aspects of the social situation surrounding the case we presented.

A key question for cognitive theories of reasoning is whether logical reasoning is inherently a sentential linguistic process or a process requiring spatial manipulation and search. We addressed this question in an event-related fMRI study of syllogistic reasoning, using sentences with and without semantic content. Our findings indicate involvement of two dissociable networks in deductive reasoning. During content-based reasoning a left hemisphere temporal system was recruited. By contrast, a formally identical reasoning task, which lacked semantic content, activated a parietal system. (...) The two systems share common components in bilateral basal ganglia nuclei, right cerebellum, bilateral fusiform gyri, and left prefrontal cortex. We conclude that syllogistic reasoning is implemented in two distinct systems whose engagement is primarily a function of the presence or absence of semantic content. Furthermore, when a logical argument results in a belief–logic conflict, the nature of the reasoning process is changed by recruitment of the right prefrontal cortex. (shrink)

Although deductive reasoning is a closed system, one's beliefs about the world can influence validity judgements. To understand the associated functional neuroanatomy of this belief-bias we studied 14 volunteers using event-related fMRI, as they performed reasoning tasks under neutral, facilitatory and inhibitory belief conditions. We found evidence for the engagement of a left temporal lobe system during belief-based reasoning and a bilateral parietal lobe system during belief-neutral reasoning. Activation of right lateral prefrontal cortex was evident when subjects inhibited a prepotent (...) response associated with belief-bias and correctly completed a logical task, a finding consistent with its putative role in cognitive monitoring. By contrast, when logical reasoning was overcome by belief-bias, there was engagement of ventral medial prefrontal cortex, a region implicated in affective processing. This latter involvement suggests that belief-bias effects in reasoning may be mediated through an influence of emotional processes on reasoning. (shrink)

This paper argues that for Nietzsche it is only when the strong type decays on its own terms that it is possible for a weak type to come into dominance by inverting the values of the strong. It sets right a latent inconsistency in Deleuze’s work, Nietzsche and Philosophy , which traces back the origin of decadence to the subterranean struggle between reactive forces. I show that Deleuze’s reading runs contrary to his own contention that for Nietzsche the negative is (...) a result of activity. I argue that the decadence of the strong is a consequence of its very creative activity and abundant health. Relying on Nietzsche’s later works, I isolate and analyze four typical traits of the strong type which not only determine this type as what it is but also make it vulnerable to decadence. (shrink)

In matters of discontinuation of life-sustaining treatment, traditional role of the family to speak on behalf of the incompetent patient is questionable. We explore the reasons why physicians perceive patient autonomy to be transferrable to family members. Principle of patient autonomy may not suffice when futile treatment is demanded and may serve to erode the ethical integrity of medical profession. An enhanced role for bioethics committees is proposed when physicians propose to discontinue life-sustaining treatment against the wishes of the patient (...) or their families. (shrink)

In this article, we examine the American Institute of Certified Public Accountants’ (AICPA) efforts to conceal the offshoring of tax return preparation services by U.S. Certified Public Accountants (CPAs) through recommending an inadequate disclosure format for this type of work. We draw on Giddens’ theory of trust and expert systems, the professionalism literature, and Flyvbjerg’s concept of power to analyze the underlying agenda behind the revised ethics rulings (AICPA Ethics Ruling No. 112 under Rule 102, No. 12 under Rule 201, (...) and No. 1 under Rule 301). Specifically, we examine (1) the AICPA leadership’s stated professional justifications for outsourcing and its recommended client disclosures, (2) risks associated with outsourcing tax return preparation work overseas and the trust issues that result, and (3) the resistance to the AICPA leadership’s recommended outsourcing disclosure rules within the rank and file of the CPA profession. We argue that our analysis reveals the AICPA’s on-going promotion of their private interests, thus continuing to raise systemic concerns regarding the public’s trust in the U.S. public accounting profession. (shrink)

Cognitive science uses the notion of computational information processing to explain cognitive information processing. Some philosophers have argued that anything can be described as doing computational information processing; if so, it is a vacuous notion for explanatory purposes.An attempt is made to explicate the notions of cognitive information processing and computational information processing and to specify the relationship between them. It is demonstrated that the resulting notion of computational information processing can only be realized in a restrictive class of dynamical (...) systems called physical notational systems (after Goodman's theory of notationality), and that the systems generally appealed to by cognitive science-physical symbol systems-are indeed such systems. Furthermore, it turns out that other alternative conceptions of computational information processing, Fodor's (1975) Language of Thought and Cummins' (1989) Interpretational Semantics appeal to substantially the same restrictive class of systems. (shrink)

It is proposed that there are important generalizations about problem solving in design activity that reach across specific disciplines. A framework for the study of design is presented that (a) characterizes design as a radial category and fleshes out the task environment of the prototypical cases; (b) takes the task environment seriously; (c) shows that this task environment occurs in design tasks, but does not occur in every nondesign task; (d) explicates the impact of this task environment on the design (...) problem space; and (e) demonstrates that, given the structure of the information-processing system, the features noted in the problem spaces of design tasks will not all occur in problem spaces where the task environment is vastly different. This analysis leads to the claim that there are a set of invariant features in the problem spaces of design situations that collectively constitute a design problem space. Protocol studies are reported in which the problem spaces of three design tasks in architecture, mechanical engineering, and instructional design are explored and compared with several protocols from nondesign problem-solving tasks. (shrink)

It is proposed that there are important generalizations about problem solving in design activity that reach across specific disciplines. A framework for the study of design is presented that (a) characterizes design as a radial category and fleshes out the task environment of the prototypical cases; (b) takes the task environment seriously; (c) shows that this task environment occurs in design tasks, but does not occur in every nondesign task; (d) explicates the impact of this task environment on the design (...) problem space; and (e) demonstrates that, given the structure of the information-processing system, the features noted in the problem spaces of design tasks will not all occur in problem spaces where the task environment is vastly different. This analysis leads to the claim that there are a set of invariant features in the problem spaces of design situations that collectively constitute a design problem space. Protocol studies are reported in which the problem spaces of three design tasks in architecture, mechanical engineering, and instructional design are explored and compared with several protocols from nondesign problem-solving tasks. (shrink)

A symbolic computer model, employing the perceptual strategy, is presented for solving Tower of Hanoi problems. The model is calibrated—in terms of the number of problems solved, time taken, and number of moves made—to the performance of 20 normal subjects. It is then “lesioned” by increasing the decay rate of elements in working memory to model the performance of 20 patients with lesions to the prefrontal cortex. The model captures both the main effects of subject groups (patients and normal controls) (...) performance, and the subject groups (patients and normal controls) by problem difficulty interactions. This leads us to support the working memory hypothesis of frontal lobe functions, but for a narrow range of problems. (shrink)

There is an important hemispheric distinction in the functional organization of prefrontal cortex (PFC) that has not been fully recognized and explored. Research with split-brain patients provides considerable evidence for a left hemisphere (LH) “interpreter” that abhors indeterminacy and automatically draws inferences to complete patterns (real or imaginary). It is suggested that this “interpreter” function may be a byproduct of the linguistic capabilities of the LH. This same literature initially limited the role of the right hemisphere (RH) to little more (...) than visual organization. Recent reviews have garnered evidence for several different roles for the right PFC in reasoning, problem solving, and decision-making. We here focus on the beneficial but neglected role of indeterminacy in real-world problem solving and argue that the right PFC complements the left PFC “interpreter” by maintaining, and even enhancing indeterminacy. Successful real-world functioning is a delicate balancing act between these two systems. (shrink)

We respond to Farah (1994) by making some general remarks about information encapsulation and locality and asking how these are violated in her computational models. Our point is not that we disagree, but rather that Farah's treatment of the issues is not sufficiently rigorous to allow an evaluation of her claims.

Many cognitive accounts of emotional processing assume that emotions have representational content that can be influenced by beliefs and desires. It is generally thought that emotions also have non-cognitive, affective components, including valence and arousal. To clarify the impact of cognition on these affective components we asked participants to rate sentences along cognitive and affective dimensions. For the former case, participants rated the believability of the material. For the latter case, they provided valence and arousal ratings. Across two experiments, we (...) show that valence and arousal are differently influenced by beliefs, suggesting that these two largely independent affective components of emotion differ in their cognitive penetrability. While both components depended upon overall comprehension of sentence meaning, only valence was influenced by the consistency of the sentences with participants’ beliefs (i.e., whether it was believable or unbelievable). We discuss the implications of these findings for understanding cognition–emotion relationships. (shrink)

Spirituality in the workplace is gaining recognition and value among researchers, academicians, and business professionals. The aim of this paper is to examine the impact of spirituality in the workplace on job satisfaction by measuring four dimensions of spirituality in the workplace: meaningful work, sense of community, organizational values, and compassion. The impact of each dimension on job satisfaction is hypothesized. A cross-sectional survey was used to collect data from 100 payroll employees in private insurance companies in Punjab. A correlation (...) analysis showed a positive relationship between all the dimensions of spirituality in the workplace and job satisfaction. A regression analysis revealed that although all the dimensions of spirituality in the workplace are important, organizational values and a sense of community are the most important in terms of the job satisfaction level of employees. This work will help insurance companies to better understand the concept of spirituality in the workplace and its importance. Insurance companies can improve their functioning by encouraging employee spirituality in the workplace. (shrink)