Biomedical research, especially pharmaceutical research, has been criticised for engaging in practices that lead to over-estimations of the effectiveness of medical treatments. A central issue concerns the reporting of absolute and relative measures of medical effectiveness. In this paper we critically examine proposals made by Jacob Stegenga to (a) give priority to the reporting of absolute measures over relative measures, and (b) downgrade the measures of effectiveness (effect sizes) of the treatments tested in clinical trials (Stegenga, 2015a). After exposing significant (...) flaws in a central case study used by Stegenga to bolster his first proposal (a), we go on to argue that neither of these proposals is defensible (a or b). We defend the practice, in line with the New England Journal of Medicine, of reporting both absolute and relative measures whenever feasible. (shrink)

This paper continues the defense of a version of scientific realism, Tautological Scientific Realism, that rests on the claim that, excluding some areas of fundamental physics about which doubts are entirely justified, many areas of contemporary science cannot be coherently imagined to be false other than via postulation of radically skeptical scenarios, which are not relevant to the realism debate in philosophy of science. In this paper we discuss, specifically, the threats of meaning change and reference failure associated with the (...) Kuhnian tradition, which depend on a descriptivist approach to meaning, and we argue that descriptivism is not the right account of the meaning and reference of theoretical terms. We suggest that an account along the lines of the causal-historical theory of reference provides a more faithful picture of how terms for unobservable theoretical entities and properties come to refer; we argue that this picture works particularly well for TSR. In the last section we discuss how our account raises concerns specifically for perspectival forms of scientific realism. (shrink)

The topics of gravitational field energy and energy-momentum conservation in General Relativity theory have been unjustly neglected by philosophers. If the gravitational field in space free of ordinary matter, as represented by the metric g ab itself, can be said to carry genuine energy and momentum, this is a powerful argument for adopting the substantivalist view of spacetime.This paper explores the standard textbook account of gravitational field energy and argues that (a) so-called stress-energy of the gravitational field is well-defined neither (...) locally nor globally; and (b) there is no general principle of energy-momentum conservation to be found in General Relativity. I discuss the nature and justification of the zero-divergence law for ordinary stress-energy, and its possible connection with the failure of General Relativity to realise Mach's principle. (shrink)

The goal of this paper is to sketch and defend a new interpretation or 'theory' of objective chance, one that lets us be sure such chances exist and shows how they can play the roles we traditionally grant them. The account is 'Humean' in claiming that objective chances supervene on the totality of actual events, but does not imply or presuppose a Humean approach to other metaphysical issues such as laws or causation. Like Lewis (1994) I take the Principal Principle (...) (PP) to be the key to understanding objective chance. After describing the main features of Humean objective chance (HOC), I deduce the validity of PP for Humean chances, and end by exploring the limitations of Humean chance. (shrink)

Since the death of strong reductionism, philosophers of science have expanded the horizons of their understandings of the physical, mental, and social worlds, and the complex relations among them. To give one interesting example, John Dupre has endorsed a notion of downward causation: ‘higher-level’ events causing events at a ‘lower’ ontological level. For example, my intention to type the letter ‘t’ causes the particular motions experienced by all the atoms in my left forefinger as I type it. The proper explanation (...) of the motions of an atom at the tip of my forefinger primarily involves my intentions, rather than the immediately preceding motions of other nearby atoms, or any other such particle–level events. (shrink)

mechanism" is frequently encountered in the social science literature, but there is considerable confusion about the exact meaning of the term. The article begins by addressing the main conceptual issues. Use of this term is the hallmark of an approach that is critical of the explanatory deficits of correlational analysis and of the covering-law model, advocating instead the causal reconstruction of the processes that account for given macro-phenomena. The term "social mechanisms" should be used to refer to recurrent processes generating (...) a specific kind of outcome. Explanation of social macro-phenomena by mechanisms typically involves causal regression to lower-level elements, as stipulated by methodological individualism. While there exist a good many mechanism models to explain emergent effects of collective behavior, we lack a similarly systematic treatment of generative mechanisms in which institutions and specific kinds of structural configurations play the decisive role. Key Words: causal regression • correlational analysis • emergent effects • micro-macro processes • social mechanisms • structural determinants. (shrink)

The underdetermination of theory by evidence must be distinguished from holism. The latter is a doctrine about the testing of scientific hypotheses; the former is a thesis about empirically adequate logically incompatible global theories or "systems of the world". The distinction is crucial for an adequate assessment of the underdetermination thesis. The paper shows how some treatments of underdetermination are vitiated by failure to observe this distinction, and identifies some necessary conditions for the existence of multiple empirically equivalent global theories. (...) We consider how empiricists should respond to the possibility of such systems of the world. (shrink)

This book explains how we can understand objective chance in a metaphysically neutral way, as reducible to certain patterns that can be discerned in the actual events of our world.

In this paper I defend fundamental physical laws from the arguments mounted by Nancy Cartwright in her (1999) book The Dappled World (and other publications). I argue, positively, that we have a good deal of evidence for mathematical laws—not just causal capacities—underlying many natural phenomena. I also argue, negatively, that Cartwright's main arguments unfairly demand that a fundamentalist be a strong reductionist.

Classical statistical mechanics posits probabilities for various events to occur, and these probabilities seem to be objective chances. This does not seem to sit well with the fact that the theory’s time evolution is deterministic. We argue that the tension between the two is only apparent. We present a theory of Humean objective chance and show that chances thus understood are compatible with underlying determinism and provide an interpretation of the probabilities we find in Boltzmannian statistical mechanics.

The story of Einstein's struggle to create a general theory of relativity, and his early discontentment with the final form of the theory , is well known in broad outline. Thanks to the work of John Norton and others, much of the fine detail of the story is also now known. One aspect of Einstein's work in this period has, however, been relatively neglected: Einstein's commitment to Mach's ideas on inertia, and the influence this commitment had on Einstein's work on (...) general relativity from 1907 to 1918. In this paper published writings and archival material are examined, to try to reconstruct the details of Einstein's thinking about inertia and gravitation, and the role that Mach's ideas played in Einstein's crucial work on the general theory. By the end, a clear picture of Einstein's conceptions of Mach's ideas on inertia, and their philosophical motivations, will emerge. Several surprising conclusions also emerge: Einstein's desire for a Machian gravitation theory was the central force driving his work from 1912 to 1915, keeping him going despite numerous frustrating setbacks; Einstein's continued commitment to Mach's ideas in 1916–1917 kept him at work trying various strategies of modification of the field equations, in order to exclude anti-Machian solutions ; and as late as early 1918, Einstein was ready to call the whole General Theory a failure if no way of squaring it with Mach's ideas on inertia could be found. But by 1920 Einstein advocated a view that granted spacetime independent existence with physical qualities of its own, a complete break with his earlier Machian views. (shrink)

The traditional absolutist-relationist debate is still clearly formulable in the context of General Relativity Theory (GTR), despite the important differences between Einstein's theory and the earlier context of Newtonian physics. This paper answers recent arguments by Robert Rynasiewicz against the significance of the debate in the GTR context. In his (1996) (‘Absolute vs. Relational Spacetime: An Outmoded Debate?’), Rynasiewicz argues that already in the late nineteenth century, and even more so in the context of General Relativity theory, the terms of (...) the original Descartes–Newton–Leibniz dispute about space are not to be found. Nineteenth-century ether theories of electromagnetism, and the metric field of GTR, he claims, do not lend themselves to being interpreted clearly as either absolute space à la Newton, or relational structures à la either Descartes or Leibniz. I argue that, while in some imaginable theories Rynasiewicz's claim that the classical debate dissolves would be correct, in fact in the most important historical theories he discusses, this is not the case. In particular, I argue that in both Lorentz's ether theory and General relativity theory, there is a clear and compelling way to establish connections to the classical absolutist-relationist disputes, and that in both these theories it is the absolutist position that is prima facie victorious. To support my arguments and give a clear overview of the whole debate, I end by offering definitional sketches of relationism and absolutism (substantivalism) about spacetime in the context of contemporary physics. The sketches show the clear connections between these views today and their ancestors in Newton and Leibniz. But at the same time, they indicate how both views are not just claims about existing physical theories, but rather also bets about how future physics will clarify the ontological picture. (shrink)

This book provides the first detailed account of Gramsci's work in the context of current critical and socio-cultural debates. Renate Holub argues that Gramsci was ahead of his time in offering a theory of art, politics and cultural production. Gramsci's achievement is discussed particularly in relation to the Frankfurt School (Adorno, Horkheimer, Benjamin, Bloch, Habermas), to Brecht's theoretical writings and to thinkers in the phenomenological tradition especially Merleau-Ponty. She argues for Gramsci's continuing relevance at a time of retreat from (...) Marxist positions on the postmodern left. Antonio Gramsci is distinguished by its range of philosophical grasp, its depth of specialized historical scholarship, and its keen sense of Gramsci's position as a crucial figure in the politics of contemporary cultural theory. (shrink)

In recent years attacks on the Kripke-Putnam approach to natural kinds and natural kind terms have proliferated. In a recent paper, Häggqvist and Wikforss (The British Journal for the Philosophy of Science, 1–23, 2017) attack the once-dominant essentialist account of natural kinds. Häggqvist & Wikforss also suggest that it is time to return to some sort of cluster-based descriptivist semantics for natural kind terms, thus targeting both the metaphysical and semantic tenets that underpin the Kripke-Putnam approach. In our paper we (...) want to challenge both parts of Häggqvist and Wikforss’ project. We will argue that the anti-essentialist considerations and arguments they raise against the Kripke-Putnam view are far from compelling in some cases, and certainly not decisive against a reasonable form of the view. On the semantic side, although Häggqvist and Wikforss give few details about what a viable cluster-based descriptivist theory should look like, we will argue that one can already see the approach to be a non-starter. Ignorance and error arguments of the kinds provided by Kripke and Putnam continue to be decisive objections. The only way we can see to save the cluster descriptivist approach is to make the essential properties postulated by Kripke and Putnam become essential features of the descriptive cluster. But this makes the success of the approach parasitic on the correctness of the Kripke-Putnam view. (shrink)

Modal logic is one of the most widely applied logical formalisms. Systems of modal logic are being used in many disciplines, ranging from artificial intelligence, computer science, mathematics, formal grammar and semantics to philosophy. This volume presents substantial recent advances in the relational and the algorithmic treatment of modal logics. It contains papers from the fifth conference on "Advances in Modal logic," held in Manchester (UK) in September 2004. Written by leading experts in the field, the present book is indispensable (...) for any advanced student and researcher in pure and applied modal logic. (shrink)

Wahrnehmen - was ist das? Worauf kommt es an bei der Wahrnehmung sozialer Wirklichkeit? Welche Zugange sind produktiv fur die Annaherung an die Wirklichkeit sozialer Berufe? Soziale bzw. helfende Berufe haben sehr viel damit zu tun, andere Menschen in ihrer Lebensbewaltigung zu unterstutzen und zu begleiten. Hierfur sind hilfreiche Strukturen in der Gesellschaft zu kultivieren. Die helfenden Professionen greifen dabei auf Menschenbilder, Gesellschaftsbilder, soziale Gegebenheiten, Strukturen und Ziele fur ein "gelingendes Leben" zu, bezogen auf den jeweils Anderen in seinen spezifischen (...) Kontexten sozialer Wirklichkeit. Den Anderen in seiner sozialen Wirklichkeit wahrnehmen ist damit Grundkompetenz in sozialen bzw. helfenden Berufen. (shrink)

This paper outlines a new interpretation of an argument of Kant's for the existence of absolute space. The Kant argument, found in a 1768 essay on topology, argues for the existence of Newtonian-Euclidean absolute space on the basis of the existence of incongruous counterparts (such as a left and a right hand, or any asymmetrical object and its mirror-image). The clear, intrinsic difference between a left hand and a right hand, Kant claimed, cannot be understood on a relational view of (...) space - for in terms of the spatial relations of their parts, there is no difference to be found. Kant's argument has been interpreted by, among others, Graham Nerlich (in 1973, Hands, Knees and Absolute Space, The Journal of Philosophy). I briefly discuss Nerlich, and then offer a different reconstruction of the argument, one that appears to be closer to Kant's text. The reconstruction, however, essentially involves ascription of primitive identity to parts of space. Comparing the Kantian absolutist account of incongruous counterparts using primitive identity to the correct relationist account, I conclude that the absolutist account pays a heavy metaphysical price, without buying any genuine explanatory advantage over the relationist. I go on to examine recent suggestions that parity-non-conservation phenomena in quantum physics allow a stronger version of Kant's challenge to relationism. On closer examination, it turns out that here too the absolutist or substantivalist must be appealing to space parts with primitive identity in order to claim an advantage over relationists; and here too, I argue the substantivalist story really has no advantage over the correct relationist account. (shrink)

Much is asked of the concept of chance. It has been thought to play various roles, some in tension with or even incompatible with others. Chance has been characterized negatively, as the absence of causation; yet also positively—the ancient Greek τυχη´ reifies it—as a cause of events that are not governed by laws of nature, or as a feature of the laws themselves. Chance events have been understood epistemically as those whose causes are unknown; yet also objectively as a distinct (...) ontological kind, sometimes called ‘pure’ chance events. Chance gives rise to individual unpredictability and disorder; yet it yields collective predictability and order—stable long-run statistics, and in the limit, aggregate behavior susceptible to precise mathematical theorems. Some authors believe that to posit chances is to abjure explanation; yet others think that chances are themselves explanatory. During the Enlightenment, talk of ‘chance’ was regarded as unscientific, unphilosophical, the stuff of superstition or ignorance; yet today it is often taken to be a fundamental notion of our most successful scientific theory, quantum mechanics, and a central concept of contemporary metaphysics. Chance has both negative and positive associations in daily life. The old word in English for it, hazard, which derives from French and originally from Arabic, still has unwelcome connotations of risk; ‘chance’ evokes uncertainty, uncontrollability, and chaos. Yet chance is also allied with luck, fortune, freedom from constraint, and diversity. And it apparently has various practical uses and benefits. It forms the basis of randomized trials in statistics, and of mixed strategies in decision theory and game theory; it is appealed to in order to resolve problems of fair division and other ethical.. (shrink)

On the face of it ‘deterministic chance’ is an oxymoron: either an event is chancy or deterministic, but not both. Nevertheless, the world is rife with events that seem to be exactly that: chancy and deterministic at once. Simple gambling devices like coins and dice are cases in point. On the one hand they are governed by deterministic laws – the laws of classical mechanics – and hence given the initial condition of, say, a coin toss it is determined whether (...) it will land heads or tails.2 On the other hand, we commonly assign probabilities to the different outcomes a coin toss, and doing so has proven successful in guiding our actions. The same dilemma also emerges in less mundane contexts. Classical statistical mechanics (which is still an important part of modern physics) assigns probabilities to the occurrence of certain events – for instance to the spreading of a gas that is originally confined to the left half of a container – but at the same time assumes that the relevant systems are deterministic. How can this apparent conflict be resolved? (shrink)

The epistemological problems of unification of two distinct theories are discussed. An approach related to the work of Soviet authors (Stepin, Podgoretzky and Smorodinsky) is used and developed. The notion of ‘crossbred objects’—theoretical objects with contradictory properties which are part of the domain of application of two independent theories—is introduced which helps to describe the dynamics of revolutionary theory change. The occurrence of the cross-contradiction of two theories is reconstructed and the reductionistic and the synthetic means of its elimination are (...) proposed. The results of the methodological analysis are applied to the paradox of equivalence. (shrink)

Precision medicine and digital phenotyping are two prominent data-based approaches within digital medicine. While precision medicine historically used primarily genetic data to find targeted treatment options, digital phenotyping relies on the usage of big data deriving from digital devices such as smartphones, wearables and other connected devices. This paper first focusses on the aspect of data type to explore differences and similarities between precision medicine and digital phenotyping. It outlines different ways of data collection and production and the consequences thereof. (...) Second, it shows how these sorts of data influence dominant beliefs in the field: The field of precision medicine relying on the dominant understanding of ‘genetic determinism’ imported from genetics, digital phenotyping building on the logic of ‘data fundamentalism’. In the end, the analysis shows how digital data informs potentials as well as challenges of precision medicine and digital phenotyping: a better health care for individuals connected with individualisation and responsibilisation for all, with a prognosed shift from reactive to preventive medicine. Additionally, data-based approaches might facilitate epistemological and ontological redirections for the whole field of medicine that will also affect knowledge production and a reassessment of the value of different types of knowledge with all its consequences. Institutionally, it might lead to shifts in distribution of power to experts in big data related technologies, i.e. private companies. (shrink)

Renate Holub provides a critical introduction to the philosophical foundations of human rights as developed by the Italian philosopher Giambattista Vico [1668-1744]. She demonstrate the profoundly innovative principles he contributed to and his contemporary relevance for a global theory of justice. Leading twentieth century transatlantic intellectuals, like Joseph Schumpeter, Arthur Nussbaum, Robert Cox who, though for quite different ultimate purposes, were variably working at the intersections between sociology, economic analysis, and international legal thought, squarely recognized the gravitas of the (...) unprecedented conceptual reach of the principles governing Vico’s social science. What is central to Vico’s international philosophy is an understanding of civilizational history not marked by permanent violence between individuals or groups of people. Rather, it is an understanding which outlines a broad historical tendency towards the reduction of violence in the internal and external organizations of social relations of peoples in all global regions. Vico’s political thought developed significant elements for a global theory of justice based not on legitimations of violence, as ‘just war’ theories, but for structuring, however minimally, the conditions of ‘permanent just global peace.’. (shrink)

Recent developments around the sharing economy bring to the fore questions of governability and broader societal benefit—and subsequently the need to explore effective means of public governance, from nurturing, on the one hand, to restriction, on the other. As sharing is a predominately urban phenomenon in modern societies, cities around the globe have become both locus of action and central actor in the debates over the nature and organization of the sharing economy. However, cities vary substantially in the interpretation of (...) potential opportunities and challenges, as well as in their governance responses. Building on a qualitative comparative analysis of 16 leading global cities, our findings reveal four framings of the sharing economy: ‘societal endangerment,’ ‘societal enhancement,’ ‘market disruption,’ and ‘ecological transition.’ Such framings go hand in hand with patterned governance responses: although there is considerable heterogeneity in the combination of public governance strategies, we find specific configurations of framings and public governance strategies. Our work reflects the political and ethical debates on various economic, social, and moral issues related to the sharing economy, and contributes to a better understanding of the field-level institutional arrangements—a prerequisite for examining moral behavior of sharing economy organizations. (shrink)

We prove completeness and decidability results for a family of combinations of propositional dynamic logic and unimodal doxastic logics in which the modalities may interact. The kind of interactions we consider include three forms of commuting axioms, namely, axioms similar to the axiom of perfect recall and the axiom of no learning from temporal logic, and a Church–Rosser axiom. We investigate the influence of the substitution rule on the properties of these logics and propose a new semantics for the test (...) operator to avoid unwanted side effects caused by the interaction of the classic test operator with the extra interaction axioms. (shrink)