Cloud computing paradigm is growing rapidly, and it allows users to get services via the Internet as pay-per-use and it is convenient for developing, deploying, and accessing mobile applications. Currently, security is a requisite concern owning to the open and distributed nature of the cloud. Copious amounts of data are responsible for alluring hackers. Thus, developing efficacious IDS is an imperative task. This article analyzed four intrusion detection systems for the detection of attacks. Two standard benchmark datasets, namely, NSL-KDD and (...) UNSW-NB15, were used for the simulations. Additionally, this study highlights the proliferating challenges for the security of sensitive user data and gives useful recommendations to address the identified issues. Finally, the projected results show that the hybridization method with support vector machine classifier outperforms the existing techniques in the case of the datasets investigated. (shrink)

Coronavirus disease 2019 is a fast-developing viral pandemic spreading across the globe. Due to lack of availability of proven medicines against COVID-19, physicians have resorted to treatments through large trials of investigational drugs with poor evidence or those used for similar diseases. Large trials randomize 100–500+ patients at multiple hospitals in different countries to either receive these drugs or standard treatment. In order to expedite the process, some regulatory agencies had also given permission to use drugs approved for other diseases, (...) despite a lack of evidence of efficacy in COVID-19. In this review, we highlight the potential ethical issues that should be addressed during the use of investigational drugs with little prior evidence as a treatment options during a pandemic. We discuss the impact of design of randomized clinical trials using LOTUS trial as an example and that of off-label use of drugs like chloroquine/hydroxychloroquine on the safety of patients during COVID-19. We conclude that the adaptive randomized clinical trial designs offer a flexible and efficient approach, enabling patients to quickly switch to successful treatments, while minimizing the number of patients on standard of care. Randomized clinical trial design should consider blinding of investigators and only representative patients who can provide consent should be included. We also conclude the emergency approvals of drugs should be carefully issued and off-label use should be restricted in pandemics. Streamlined regulatory guidelines for emergency drug use in a pandemic can also help in providing benefit and minimizing harm to patients in the future. (shrink)

Drawing on social cognitive theory, this study extends our understanding of the relationship between ethical leadership and employee work engagement, by exploring self-efficacy as an important mediating variable. In addition, we propose that the quality of LMX moderates the relationships such that the direct and indirect relationships between ethical leadership, self-efficacy, and work engagement are stronger when the quality of LMX is high. Data collected in two-waves from 373 respondents working in different manufacturing organizations of Pakistan supported our hypothesized theoretical (...) model. Theoretical and practical implications are discussed. (shrink)

Mitter's study argues that until the late Qing, concepts of international order and justice were alien to China's imperial rulers. Subsequently, however, in the nineteenth and early twentieth centuries, China perceived itself to be the victim in an unjust world of aggressive, powerful, Western states. Contemporary Chinese perceptions of a just international order have been shaped by such past experiences and encompass a strong element of restitution. Its justice claims start with the Chinese state itself rather than with the needs (...) of a broader global community. (shrink)

The focus of this study is an examination of what it means to be a legal person and the role that the law plays in bestowing the legal status of being a person. This study highlights the underpinning rationalities and human interest that establish a hierarchy between person, defined as “human”, at a superior level to everything else, defined as “nonhuman”. In this respect, there is a core notion concerning human exceptionalism based on the rational sovereignty that justifies and consolidates (...) the mastery of nature. To understand the fundamental premises of legal personhood, it begins from the first usage of person in history and philosophy, since the concept of legal personhood has been established through historical and philosophical developments. Analysing the meaning of person through different conceptualisations can allow a deeper insight into the legal interpretation of personhood. As a result of such investigation, two main dualistic structures of legal personhood reveal: the person-property dualism and the human being-person dualism. Thus, legal personhood simultaneously includes personalisation and depersonalisation, and always operates in a hierarchical array. Although the division between persons and things in the concept of personhood is rigid, being a “person” or a “thing” is open to interpretation in different circumstances through legal practices of exclusion and inclusion. Recently, there have been an increasing number of court rulings and a tendency of legislation to recognise the legal personhood of natural entities as a legal way of conserving the environment. This leads to an interpretation that legal recognition is a matter of institutional interest and attempts. Nevertheless, legal practitioners mostly prefer to confer certain rights or the status of a legal person on nature without the consideration of legal personhood’s background as seen in the case discussed in this study - the Tierra Digna case in Colombia. While this study endeavours to demonstrate the anthropocentric standard view of legal personhood, its principal purpose is to indicate the malleable nature of legal personhood as a product of legal fiction. In this context, this study aims to conclude that law’s imaginary nature should be used for producing a new legal reasoning and for offering a real paradigm shift that is congruent with the plasticity of and the fluidity of nature. (shrink)

This article examines the development of the ritual of mubāhala, a category of oaths and mutual self-cursing, during which two individuals seek to confirm the veracity of their creedal position by appealing to God’s curse upon them. Based on a prophetic precedent embedded in Q 3:61 and reported as a challenge purportedly employed by the Companions Ibn Masʿūd and Ibn ʿAbbās, I argue that the practice of resorting to mubāhala in the Sunni tradition goes through two main phases of reinvention (...) and legitimation before its reappearance in the contemporary Muslim world. The first phase belongs to the anti-Monist controversies of the seventh to ninth/thirteenth to fifteenth centuries, while the second appears among reformist scholars starting in the late eighteenth century. (shrink)

Earlier evidence suggests that besides humans, some species of mammals and birds demonstrate visual self-recognition, assessed by the controversial “mark” test. Whereas, there are high levels of inter-individual differences amongst a single species, some species such as macaques and pigeons which do not spontaneously demonstrate mirror self-recognition can be trained to do so. We were surprised to discover that despite being widely used as a model system for avian research, the performance of zebra finches on the mark test had not (...) been studied earlier. Additionally, we studied the behavioral responses of another species of passerine songbirds to a mirror and the MSR mark test. Although a small number of adult male zebra finches appeared to display heightened responses toward the mark while observing their reflections, we could not rule out the possibility that these were a part of general grooming rather than specific to the mark. Furthermore, none of the house crows demonstrated mark-directed behavior or increased self-exploratory behaviors when facing mirrors. Our study suggests that self-directed behaviors need to be tested more rigorously in adult male zebra finches while facing their reflections and these findings need to be replicated in a larger population, given the high degree of variability in mirror-directed behaviors. (shrink)

Bacteria use trans‐translation to rescue stalled ribosomes and target incomplete proteins for proteolysis. Despite similarities between tRNAs and transfer‐messenger RNA (tmRNA), the key molecule for trans‐translation, new structural and biochemical data show important differences between translation and trans‐translation at most steps of the pathways. tmRNA and its binding partner, SmpB, bind in the A site of the ribosome but do not trigger the same movements of nucleotides in the rRNA that are required for codon recognition by tRNA. tmRNA‐SmpB moves from (...) the A site to the P site of the ribosome without subunit rotation to generate hybrid states, and moves from the P site to a site outside the ribosome instead of to the E site. During catalysis, transpeptidation to tmRNA appears to require the ribosomal protein bL27, which is dispensable for translation, suggesting that this protein may be conserved in bacteria due to trans‐translation. These differences provide insights into the fundamental nature of trans‐translation, and provide targets for new antibiotics that may have decrease cross‐reactivity with eukaryotic ribosomes. (shrink)

ABSTRACTAdults use a variety of strategies to reason about fraction magnitudes, and this variability is adaptive. In two studies, we examined the relationships between mathematics anxiety, working memory, strategy variability and performance on two fraction tasks: fraction magnitude comparison and estimation. Adults with higher mathematics anxiety had lower accuracy on the comparison task and greater percentage absolute error on the estimation task. Unexpectedly, mathematics anxiety was not related to variable strategy use. However, variable strategy use was linked to more accurate (...) magnitude comparisons, especially among adults with lower working memory performance or those who use mathematics less frequently, as well as lower PAE on the estimation task. These findings shed light on the role of strategy variability in fraction problem solving and demonstrate a link between mathematics anxiety and fraction magnitude reasoning, a key predictor of general mathematics achievement. (shrink)

Wittgenstein’s philosophical methods have had a wide influence in the fields of ethics and moral philosophy. The aim of the volume Ethics After Wittgenstein: Contemplation and Critique is to outlin...

This paper presents a profile of the welfare regime in Lebanon which is posited on the twin precepts of human ethics and welfare particularism. It highlights the key role that moral values play in the conceptualization and implementation of social policy, as well as in the measurement of welfare outcomes. This is marked by the dominance of duty, traditionalism and elitism in the ethics of religious welfare in Lebanon. The paper argues that the social welfare regime in Lebanon overlaps with (...) the debates on the ethics of care and on virtue ethics in Western moral philosophy. This is also linked in with contemporary conceptualizations of religious ethics in Judaism, Christianity and Islam. The paper asserts that religious ethics is a valid endeavour in its own right and an ever more pertinent subject matter for the study of social welfare and social policy. This challenges the traditional dichotomy between reason and faith which has subdued the relevance of religion to public life. Indeed, religion, the nuclear family and clientelism networks are shown to play a critical role in Lebanese social welfare, such that, in spite of state incapacity, the welfare regime there cannot be considered rudimentary. The method adopted for this research was a large qualitative case study involving service providers and users at the Ministry of Social Affairs and five leading Christian and Muslim religious welfare organizations in Lebanon. (shrink)

This book offers a resolution of the paradox posed by the pleasure of tragedy by returning to its earliest articulations in archaic Greek poetry and its subsequent emergence as a philosophical problem in Plato's Republic. Socrates' claim that tragic poetry satisfies our 'hunger for tears' hearkens back to archaic conceptions of both poetry and mourning that suggest a common source of pleasure in the human appetite for heightened forms of emotional distress. By unearthing a psychosomatic model of aesthetic engagement implicit (...) in archaic poetry and philosophically elaborated by Plato, this volume not only sheds new light on the Republic's notorious indictment of poetry, but also identifies rationally and ethically disinterested sources of value in our pursuit of aesthetic states. In doing so the book resolves an intractable paradox in aesthetic theory and human psychology: the appeal of painful emotions. (shrink)

The correlation coefficient between two variables plays an important role in statistics. Also, the accuracy of relevance assessment depends on information from a set of discourses. The data collected from numerous statistical studies are full of exceptions. The Pythagorean fuzzy hypersoft set is a parameterized family that deals with the subattributes of the parameters and an appropriate extension of the Pythagorean fuzzy soft set. It is also the generalization of the intuitionistic fuzzy hypersoft set, which is used to accurately assess (...) insufficiency, anxiety, and uncertainties in decision-making. The PFHSS can accommodate more uncertainties compared to the IFHSS, and it is the most substantial methodology to describe fuzzy information in the decision-making process. The core objective of the this study is to develop the notion and features of the correlation coefficient and the weighted correlation coefficient for PFHSS and to introduce the aggregation operators such as Pythagorean fuzzy hypersoft weighted average and Pythagorean fuzzy hypersoft weighted geometric operators under the PFHSS scenario. A prioritization technique for order preference by similarity to the ideal solution under PFHSS based on correlation coefficients and weighted correlation coefficients is presented. Through the developed methodology, a technique for solving multiattribute group decision-making problem is planned. Also, the importance of the developed methodology and its application in indicating multipurpose antivirus mask throughout the COVID-19 pandemic period is presented. A brief comparative analysis is described with the advantages, effectiveness, and flexibility of numerous existing studies that demonstrate the effectiveness of the proposed method. (shrink)

Research on human subjects is ethically justified when its anticipated results would ultimately benefit the society or public and not only the individuals participating in this research. Besides contributing to scientific knowledge, social benefits of scientific research may extend to all aspects of the public’s life including health, education, and security. In this paper, we aimed to discuss the social benefits principle as an ethical requirement for the conduct of scientific research in general and nursing research in particular. We critically (...) examined the current situation of nursing research in developing countries including its adherence to the social benefits principle and provided exemplars of both hindered and successful utilization of nursing research evidence in developing countries. We concluded that the utilization of nursing research evidence in clinical practice, education, and policy making is almost nonexistent and faces many challenges in most developing countries. Thus, most nursing research in developing countries are not currently meeting the social benefit principle of the ethical conduct of scientific research. We provided recommendations to promote the utilization of nursing research in evidence-based practice, nursing education, and health policy. (shrink)

Abstract The apparent contradictory relationship between Islam and evolution is important because it has been cited as an example of contradiction between religion and science by both thinkers in the West and Muslims. Muslim scholars and scientists mainly disagree with evolution's legitimacy. Islam's Quantum Question by Nidhal Guessoum is a unique narrative providing in one of its first chapters an overview of evolution from neo-Darwinists to creationists, including the views of scholars throughout Islamic history. Guessoum then proceeds to advocate for (...) evolution. Drawing from Nidhal Guessoum's work, I highlight the reasons why there is an apparent contradiction between Islam and science—and, in particular, Islam and evolution—which include lack of freedom of thought and misinterpretation of the Qur’an. In doing so, I suggest setting the stage for a new Einsteinian theory of evolution, which involves the dimension of time and human cognition. (shrink)

The literature on Black youth culture, especially hip-hop culture, has focused primarily on the experiences of young men, with the experiences of Black girls being all but ignored. However, the recent appearance of Black women performers, songwriters, and producers in Black popular culture has called attention to the ways in which young Black women use popular culture to negotiate social existence and attempt to express independence, self-reliance, and agency. This article is an exploration of the representations of Black womanhood as (...) expressed in the music videos of Black women performers. The author first identifies themes that reflect controlling images of Black womanhood, then those that exemplify an expression of agency, and finally those appearing ambivalent and contradictory. Overall, the music videos express how young Black women must negotiate sexuality and womanhood in their everyday lives. (shrink)

Understanding the impact of the p53 tumor suppressor pathway on the regulation of genome integrity, cancer development, and cancer treatment has intrigued scientists and clinicians for decades. It appears that the p53 pathway is a central node for nearly all cell stress responses, including: gene expression, DNA repair, cell cycle arrest, metabolic adjustments, apoptosis, and senescence. In the past decade, it has become increasingly clear that p53 function is directly regulated by poly(ADP‐ribose) polymerase‐1 (PARP‐1), a nuclear enzyme involved in DNA (...) repair signaling. Here, we will discuss the impact of PARP‐1 on p53 function, along with a recently described novel role for the reciprocal regulation of p53 regulated, PARP‐1 dependent necrosis following DNA damage. (shrink)

Study on the concept of cognition and metaphysical theory of causation in Vedanta school in Hindu philosophy.

Religion (dharma) plays a vital role in the Hindu (Sanatana) quest for understanding and practicing harmony between nature and humanity that result into the formation of a cosmological awakening, i.e. 'transcending the universe.' The importance and applicability of such new consciousness is a sign in promoting global humanism in the 21st century, where environmental ethics and sustainability are the wheels of making the future more humane and peaceful. Arne Naess, who coined the term 'deep ecology' conceiving humankind as an integral (...) part of its environment, gives credit to Gandhi. Gandhi’s contributions help to re-awaken the human spirit to self-realisation, finally leading to revelation promoting human coexistence with nature sustainably, mostly through re-interpretation of Vedantic thought. Under the SDGs (Sustainable Development Goals) the ideas of Gandhi are recognised as a path that makes human coexistence stronger, feasible and co-sharedness, sustainable in peace and harmony with nature. This essay presents ecospiritual contextuality and its vitality concerning a sustainable perspective in line with Gandhi's vision and way of life. (shrink)

Introduction: Globally, vitamin D deficiency is one of the most common deficiencies, affecting nearly half the world's population. The objective of this survey was to assess and compare the knowledge about vitamin D and the perceived state of health in Emirati and international tourist female students in Dubai, UAE. Methods: This is a cross-sectional study that took place in universities in Dubai, UAE. This survey consisted of 17 multiple choice questions. The first part of the survey assessed levels of supplementation, (...) diet and UV exposure. Another section evaluated the participants’ self-assessed state of health regarding vitamin D testing, symptoms related to vitamin D deficiency and general welbeing. The collected data were statistically analyzed using SPSS statistics for windows version 26.0 (SPSS Inc., Chicago, IL). Statistical significance was set at P<0.05. Results: 105 respondents were Emiratis and 65 were international students. The average age was 21, with an average BMI 23.3. Almost one-third of each group reported using Vitamin D supplements once weekly. The majority of both groups reported rarely getting tanned. Almost all participants reported regular consumption of Vitamin-D rich foods. In both groups, more than half reported consuming milk and cheese regularly and up to one-third reported consuming fish in a regular manner. Although more than half of the students rated their health as good; more than two-thirds reported experiencing muscle pain; only half reported having their blood Vitamin D levels measured once; half reported experiencing problems with concentration and more than three-quarters reported experiencing bad mood in the past month. The prevalence of these symptoms was almost similar across different categories of vitamin D supplementation, tanning habits, dietary intake, or nationality. No statistically significant differences were noted between the 2 groups. Conclusion: more Emirati students were aware of the association between vitamin D and osteoporosis than International tourist students (40% vs. 21.9%, respectively; p<0.05). On the other hand, both groups had lower knowledge about the relationship between vitamin D deficiency and depression, Rheumatoid Arthritis and Hypertension, and the optimal vitamin D level; however, no statistically significant differences were noted regarding this knowledge of Emiratis and international students. (shrink)

This article is a preliminary draft for initiating and commencing a new pioneer dimension of expression. To deal with higher-dimensional data or information flowing in this modern era of information technology and artificial intelligence, some innovative super algebraic structures are essential to be formulated. In this paper, we have introduced such matrices that have multiple layers and clusters of layers to portray multi-dimensional data or massively dispersed information of the plithogenic universe made up of numerous subjects their attributes, and sub-attributes. (...) For grasping that field of parallel information, events, and realities flowing from the micro to the macro level of universes, we have constructed hypersoft and hyper-super-soft matrices in a Plithogenic Fuzzy environment. These Matrices classify the non-physical attributes by accumulating the physical subjects and further sort the physical subjects by accumulating their non-physical attributes. We presented themasPlithogenicAttributiveSubjectivelyWholeHyper-Super-Soft-Matrix(PASWHSS-Matrix)andPlithogenic Subjective Attributively Whole-Hyper-Super-Soft-Matrix (PSAWHSS-Matrix). Several types of views and level-layers of these matrices are described. In addition, some local aggregation operators for Plithogenic Fuzzy Hypersoft Set (PPFHS-Set) are developed. Finally, few applications of these matrices and operators are used as numerical examples of COVID-19 data structures. (shrink)

Purpose This study aims to address the existing knowledge gap by investigating teachers’ adoption of ChatGPT for educational purposes. The study specifically focuses on identifying the factors that motivate and inhibit teachers in adoption of ChatGPT in higher education institutions (HEIs). Design/methodology/approach This research has used interpretative phenomenological analysis – a qualitative approach. Through in-depth interviews among the teachers, data was collected to identify the motivating and inhibiting factors that impacted teachers’ willingness to adopt ChatGPT. The data was collected from (...) 48 teachers working across HEIs of Uttarakhand region in India. Findings The analysis revealed seven themes under motivating factors that encourage teachers to adopt ChatGPT for their educational purposes. These include time factor, tool for competitive edge, learning enhancement tool for students, research facilitator, benefits in educational settings, troubleshooter and easy to use. On the other hand, inhibiting factors comprise five themes, which include technical difficulties, limited features for educational and research purposes, tool for handicapping innovation and creativity, lack of personal touch and ethical considerations. Practical implications The findings will be valuable for HEIs in establishing policies that promote the appropriate and effective use of ChatGPT. Moreover, the study provides recommendations to ChatGPT solution providers for improving ChatGPT services for effective adoption of ChatGPT among teachers and implementation at HEIs. Further, it contributes to the body of literature by filling a knowledge gap about teacher adoption of ChatGPT in the HEIs. Through qualitative research, the study has pinpointed specific motivating and inhibiting factors that affect teacher adoption of ChatGPT. Originality/value Unlike previous studies that primarily explored the potential advantages and drawbacks of ChatGPT in education, this research study delves deeper into the topic. It makes a substantial contribution to our understanding of ChatGPT adoption among teachers by identifying distinct factors that either motivate or inhibit teachers from adopting ChatGPT for job related purposes. The study provides novel insights that were previously mislaid, thereby introducing a fresh perspective to the existing literature. (shrink)

A questionnaire survey of 408 households explored the role of socio-economic and cultural factors in rice (Oryza sativa L.) varietal diversity management on-farm in two contrasting eco-sites in Nepal. Multiple regression outputs suggest that number of parcels of land, livestock number, number of rice ecosystems, agro-ecology (altitude), and use of chemical fertilizer have a significant positive influence on landrace diversity on-farm, while membership in farmers’ groups linked to extension services has significant but negative influence on landrace diversity. Factors with significant (...) positive influence on diversity of modern varieties on-farm were number of parcels of land and of rice ecosystems, access to irrigation, membership in farmers’ groups, and use of insecticide. Within communities, resource-endowed households maintain significantly higher varietal diversity on-farm than resource-poor households and play a significant role in conserving landraces that are vulnerable to genetic erosion and those with socio-cultural and market-preferred traits. Resource-poor households also contribute to local diversity conservation but at lower richness and area coverage levels than resource-endowed households. Households where a female had assumed the role of head of household due to death or migrant work of her husband had less diversity due to lower labor availability. Landraces with socio-cultural and market-preferred traits are few in number but have potential to be conserved on-farm. (shrink)

Academic supervision is considered an important mechanism to improve the performance of an educational institution. This article aims to investigate the situation of academic supervision in Bangladeshi Government Colleges (GCs).The article, in particular, explores the impacts of academic supervision on Bangladeshi students and teachers in developing their competencies and confidence in postsecondary educational settings. The study was conducted employing thequalitative research method and collecting data from in-depth interviews, secondary published literature, such as books, journal articles etc. The study finds that (...) effective academic supervision considerably helps students achieve their learning progress as well as teachers attain their professionalization in the GCs of Bangladesh. Various challenges exist in higher education in Bangladesh, which include the lack of resources, limited use of educational tools and technology, policy problems, lack of sufficient training and scope of research for teachers, and so on. This article has made several recommendations for improving academic supervision to enhance quality education in the Bangladeshi GCs. Philosophy and Progress, Vol#71-72; No#1-2; Jan-Dec 2022 P 97-128. (shrink)

Ethical research conduct is a cornerstone of research practice particularly when research participants include vulnerable populations. This study mapped the extent of reporting ethical research practices in studies conducted among refugees and war-affected populations in the Arab World, and assessed variations by time, country of study, and study characteristics. An electronic search of eight databases resulted in 5668 unique records published between 2000 and 2013. Scoping review yielded 164 eligible articles for analyses. Ethical research practices, including obtaining institutional approval, access (...) to the community/research site, and informed consent/assent from the research participants, were reported in 48.2, 54.9, and 53.7% of the publications, respectively. Institutional approval was significantly more likely to be reported when the research was biomedical in nature compared to public health and social, when the study employed quantitative compared to qualitative or mixed methodologies, and when the journal required a statement on ethical declarations. Institutional approval was least likely to be reported in papers that were sole-authored, when these did not mention a funding source, or when published in national journals. Similar results were obtained for access to the community site and for seeking informed consent/assent from study participants. The responsibility of inadequacies in adherence to ethical research conduct in crisis settings is born by a multitude of stakeholders including funding agencies, institutional research boards, researchers and international relief organizations involved in research, as well as journal editors, all of whom need to play a more proactive role for enhancing the practice of ethical research conduct in conflict settings. (shrink)

Osmoregulation in insects is an essential process whereby changes in hemolymph osmotic pressure induce the release of diuretic or antidiuretic hormones to recruit individual osmoregulatory responses in a manner that optimizes overall homeostasis. However, the mechanisms by which different osmoregulatory circuits interact with other homeostatic networks to implement the correct homeostatic program remain largely unexplored. Surprisingly, recent advances in insect genetics have revealed several important metabolic functions are regulated by classic osmoregulatory pathways, suggesting that internal cues related to osmotic and (...) metabolic perturbations are integrated by the same hormonal networks. Here, we review our current knowledge on the network mechanisms that underpin systemic osmoregulation and discuss the remarkable parallels between the hormonal networks that regulate body fluid balance and those involved in energy homeostasis to provide a framework for understanding the polymodal optimization of homeostasis in insects. (shrink)

This paper intends to enhance the great relevance that the promotion of reason received in the XIIth century. The main representatives of thought in this century can be considered, at least in a certain sense, as antecedents to what later was the European Illustration. Indeed their emphasis on rationality is huge.

This paper intends to show the evolution of Ethics on the High Middle Ages. The penitential books written in this period are taken as a basis for the reflection.