The specification of specific and often unique fates to individual cells as a function of their position within a developing organism is a fundamental process during the development of multicellular organisms. The development of the Drosophila embryonic central nervous system serves as an excellent model system in which to clarify the developmental mechanisms that link pattern formation to cell-type specification. The Drosophila embryonic central nervous system develops from a set of neural stem cells termed neuroblasts. Neuroblasts arise from the ectoderm (...) in an invariant pattern, and each neuroblast acquires a unique fate based on its position within this pattern. Two groups of genes recently have been demonstrated to govern the individual fate specification of neuroblasts. One group, the segment polarity genes, enables neuroblasts that develop in different anteroposterior positions to acquire different fates. The second group, referred to as the columnar genes, ensures that neuroblasts that develop in different dorsoventral domains assume different fates. When integrated, the activities of the segment polarity and columnar genes create a Cartesian coordinate system that bestows unique fates to individual neuroblasts as a function of their position of formation within the ectoderm. BioEssays 1999;21:922–931. © 1999 John Wiley & Sons, Inc. (shrink)

I defend the principle of Phenomenal Conservatism, on which appearances of all kinds generate at least some justification for belief. I argue that there is no reason for privileging introspection or intuition over perceptual experience as a source of justified belief; that those who deny Phenomenal Conservatism are in a self-defeating position, in that their view cannot be both true and justified; and that thedemand for a metajustification for Phenomenal Conservatism either is an easily met demand, or is an unfair (...) or question-begging one. (shrink)

This essay deals with the question of the morality of abortion and infanticide. The fundamental ethical objection traditionally advanced against these practices rests on the contention that human fetuses and infants have a right to life, and it is this claim that is the primary focus of attention here. Consequently, the basic question to be discussed is what properties a thing must possess in order to have a serious right to life. The approach involves defending, then, a basic principle specifying (...) a condition living things must satisfy to have a serious right to life, and the answer given makes it unlikely that this condition is satisfied by human fetuses and infants, though this tentative conclusion could be altered by future scientific studies of the development of the human brain. As things stand at the moment, however, it seems unlikely that developing humans acquire the physical basis of the psychological capacities on which the right to continued existence rests, and therefore unless there are other substantial objections to abortion and infanticide that undercut the above line of thought, the conclusion is that such practices are not intrinsically wrong. (shrink)

Transformation of the sparrow and the butterfly -- Meeting the gods of poverty in a dream -- The greatest joys of the cicada and its cast-off shell -- The owl's understanding -- The centipede questions the snake -- The toad's way of the gods -- The mysterious technique of the cat -- Afterword by William Scott Wilson.

We are material beings in a material world, but we are also beings who have experiences and feelings. How can these subjective states be just a matter of matter? To defend materialism, philosophical materialists have formulated what is sometimes called "the phenomenal-concept strategy," which holds that we possess a range of special concepts for classifying the subjective aspects of our experiences. In Consciousness Revisited, the philosopher Michael Tye, until now a proponent of the the phenomenal-concept strategy, argues that the (...) strategy is mistaken. A rejection of phenomenal concepts leaves the materialist with the task of finding some other strategy for defending materialism. Tye points to four major puzzles of consciousness that arise: How is it possible for Mary, in the famous thought experiment, to make a discovery when she leaves her black-and-white room? In what does the explanatory gap consist and how can it be bridged? How can the hard problem of consciousness be solved? How are zombies possible? Tye presents solutions to these puzzles -- solutions that relieve the pressure on the materialist created by the failure of the phenomenal-concept strategy. In doing so, he discusses and makes new proposals on a wide range of issues, including the nature of perceptual content, the conditions necessary for consciousness of a given object, the proper understanding of change blindness, the nature of phenomenal character and our awareness of it, whether we have privileged access to our own experiences, and, if we do, in what such access consists. (shrink)

Realism concerning a given subject-matter is characterised as a semantic doctrine with metaphysical consequences, namely as the adoption, for the relevant class of statements, of a truth-conditional theory of meaning resting upon the classical two-valued semantics. it is argued that any departure from classical semantics may, though will not necessarily, be seen as in conflict with some variety of realism. a sharp distinction is drawn between the rejection of realism and the acceptance of a reductionist thesis; though intimately related, neither (...) entails the other. realism is to be classified as "naive", "semi-naive" or "sophisticated": the first of these involves an all but unintelligible epistemological component. (shrink)

The two dominant theories of consciousness argue it appeared in living beings either suddenly, or gradually. Both theories face problems. The solution is the realization that a foundational consciousness was always here, yet varying conscious states were not, and appeared gradually. Michael Tye explores this idea and the key questions it raises.

Internalists tend to impose on justification higher-level requirements, according to which a belief is justified only if the subject has a higher-level belief (i.e., a belief about the epistemic credentials of a belief). I offer an error theory that explains the appeal of this requirement: analytically, a belief is not justified if we have a defeater for it, but contingently, it is often the case that to avoid having defeaters, our beliefs must satisfy a higher-level requirement. I respond to the (...) objection that externalists who endorse this error theory will be forced to accept a radical form of scepticism. (shrink)

We propose that all actual causes are simultaneous with their direct effects, as illustrated by both everyday examples and the laws of physics. We contrast this view with the sequential conception of causation, according to which causes must occur prior to their effects. The key difference between the two views of causation lies in differing assumptions about the mathematical structure of time.

The following argument is addressed: (1) a person is morally responsible for an event's occurring only if that event's occurring was not a matter of luck; (2) no event is such that its occurring is not a matter of luck; therefore, (3) no event is such that someone is morally responsible for its occurring. Two notions of control are distinguished: restricted and complete. (2) is shown false on the first interpretation, (1) on the second. The discussion involves a distinction between (...) resultant and situational luck, And it is argued that, Even when luck's role in life, And the unfairness that stems from it, Is acknowledged, Moral responsibility remains possible. (shrink)

Related Works: Part I: Michael Zakharyaschev. Canonical Formulas for $K4$. Part I: Basic Results. J. Symbolic Logic, Volume 57, Issue 4 , 1377--1402. Project Euclid: euclid.jsl/1183744119 Part III: Michael Zakharyaschev. Canonical Formulas for K4. Part III: The Finite Model Property. J. Symbolic Logic, Volume 62, Issue 3 , 950--975. Project Euclid: euclid.jsl/1183745306.

Skeptical theists endorse the skeptical thesis (which is consistent with the rejection of theism) that we have no good reason for thinking the possible goods we know of are representative of the possible goods there are. In his newest formulation of the evidential arguments from evil, William Rowe tries to avoid assuming the falsity of this skeptical thesis, presumably because it seems so plausible. I argue that his new argument fails to avoid doing this. Then I defend that skeptical thesis (...) against objections, thereby supporting my contention that relying on its falsity is a weakness in an argument. (shrink)

Was leistete der Gedanke der selbstandigen Auswahl (Eklektik) in der Geschichte der Philosophie von Aristoteles bis zum 20. Jahrhundert, wo liegen die Anwendungsgebiete, wo seine Grenzen und warum kam der Begriff der Eklektik schon im 18. Jahrhundert zur Bezeichnung unselbstandiger Vermischung herunter? Der Schwerpunkt der umfangreichen Arbeit liegt in der Philosophie und Naturwissenschaft des 17. Jahrhunderts; sie reicht aber bis zur eklektischen Psychotherapie der Gegenwart.

There are two interrelated but distinct programs which go by the name evolutionary epistemology. One attempts to account for the characteristics of cognitive mechanisms in animals and humans by a straightforward extension of the biological theory of evolution to those aspects or traits of animals which are the biological substrates of cognitive activity, e.g., their brains, sensory systems, motor systems, etc. (EEM program). The other program attempts to account for the evaluation of ideas, scientific theories and culture in general by (...) using models and metaphors drawn from evolutionary biology (EET program). The paper begins by distinguishing the two programs and discussing the relationship between them. The next section addresses the metaphorical and analogical relationship between evolutionary epistemology and evolutionary biology. Section IV treats the question of the locus of the epistemological problem in the light of an evolutionary analysis. The key questions here involve the relationship between evolutionary epistemology and traditional epistemology and the legitimacy of evolutionary epistemology as epistemology. Section V examines the underlying ontological presuppositions and implications of evolutionary epistemology. Finally, section VI, which is merely the sketch of a problem, addresses the parallel between evolutionary epistemology and evolutionary ethics. (shrink)

A consideration of some of the most common questions about animal minds.Do birds have feelings? Can fish feel pain? Could a honeybee be anxious? For centuries, the question of whether or not animals are conscious like humans has prompted debates among philosophers and scientists. While most people gladly accept that complex mammals - such as dogs - share emotions and experiences with us, the matter of simpler creatures is much less clear. Meanwhile, the advent of the digital age and artificial (...) intelligence has created an added dimension to questions about non-human consciousness. In Tense Bees and Shell-Shocked Crabs, Michael Tye offers answers to some of today's most pressing questions about nonhuman consciousness. Blending the latest research about animal sensation with theories about the nature of consciousness, Tye develops a methodology for addressing the mysteries of the animal mind. Without endorsing any specific theory on the nature of consciousness, Tye tackles issues such as the animal experience of pain and fear, and the role of brain anatomy in determining consciousness. He then turns his attention to the artificial realm, considering whether complex robots could ever be considered conscious. Tye concludes with a discussion of how, if we consider animals conscious, this might impact our ethical obligations to them. From insects to crabs, fish to birds, Tense Bees and Shell-Shocked Crabs offers an insightful exploration of the ways in which animals relate to the world. Tense Bees and Shell-Shocked Crabs will appeal to students and scholars of philosophy and neuroscience, as well as general readers with an interest in animal and environmental ethics. (shrink)

This paper is an interpretation and defense of Richard Levins’ “The Strategy of Model Building in Population Biology,” which has been extremely influential among biologists since its publication 40 years ago. In this article, Levins confronted some of the deepest philosophical issues surrounding modeling and theory construction. By way of interpretation, I discuss each of Levins’ major philosophical themes: the problem of complexity, the brute-force approach, the existence and consequence of tradeoffs, and robustness analysis. I argue that Levins’ article is (...) concerned, at its core, with justifying the use of multiple, idealized models in population biology. (shrink)

_Paradoxes from A to Z, Third edition_ is the essential guide to paradoxes, and takes the reader on a lively tour of puzzles that have taxed thinkers from Zeno to Galileo, and Lewis Carroll to Bertrand Russell. Michael Clark uncovers an array of conundrums, such as Achilles and the Tortoise, Theseus’ Ship, and the Prisoner’s Dilemma, taking in subjects as diverse as knowledge, science, art and politics. Clark discusses each paradox in non-technical terms, considering its significance and looking at (...) likely solutions. This third edition is revised throughout, and adds nine new paradoxes that have important bearings in areas such as law, logic, ethics and probability. Paradoxes from A to Z, Third edition is an ideal starting point for those interested not just in philosophical puzzles and conundrums, but anyone seeking to hone their thinking skills. (shrink)

Published very shortly before his death in February 1976, Meaning is the culmination of Michael Polanyi's philosophic endeavors.

We provide a new interpretation of Zeno’s Paradox of Measure that begins by giving a substantive account, drawn from Aristotle’s text, of the fact that points lack magnitude. The main elements of this account are (1) the Axiom of Archimedes which states that there are no infinitesimal magnitudes, and (2) the principle that all assignments of magnitude, or lack thereof, must be grounded in the magnitude of line segments, the primary objects to which the notion of linear magnitude applies. Armed (...) with this account, we are ineluctably driven to introduce a highly constructive notion of (outer) measure based exclusively on the total magnitude of potentially infinite collections of line segments. The Paradox of Measure then consists in the proof that every finite or potentially infinite collection of points lacks magnitude with respect to this notion of measure. We observe that the Paradox of Measure, thus understood, troubled analysts into the 1880’s, despite their knowledge that the linear continuum is uncountable. The Paradox was ultimately resolved by Borel in his thesis of 1893, as a corollary to his celebrated result that every countable open cover of a closed line segment has a finite sub-cover, a result he later called the “First Fundamental Theorem of Measure Theory.” This achievement of Borel has not been sufficiently appreciated. We conclude with a metamathematical analysis of the resolution of the paradox made possible by recent results in reverse mathematics. (shrink)

Many philosophers, following David Lewis, believe that we should look to counterpart theory, not quantified modal logic, as a means of understanding modal discourse. We argue that this is a mistake. Significant parts of modal discourse involve either implicit or explicit reference to what is actually the case, raising the question of how talk about actuality is to be represented counterpart-theoretically. By considering possible modifications of Lewis's counterpart theory, including actual modifications due to Graeme Forbes and Murali Ramachandran, we argue (...) that no coherent version of counterpart theory can provide a plausible representation of talk about actuality, and so, we conclude, counterpart theory should be rejected. (shrink)

Three leading philosopher-logicians present a clear and concise overview of formal theories of truth, explaining key logical techniques. Truth is as central topic in philosophy: formal theories study the connections between truth and logic, including the intriguing challenges presented by paradoxes like the Liar.

About twenty-five years ago, Charles Parsons published a paper that began by asking why we still discuss the Liar Paradox. Today, the question seems all the more apt. In the ensuing years we have seen not only Parsons’ work (1974), but seminal work of Saul Kripke (1975), and a huge number of other important papers. Too many to list. Surely, one of them must have solved it! In a way, most of them have. Most papers on the Liar Paradox offer (...) some explanation of the behavior of paradoxical sentences, and most also offer some extension for the predicate ‘true’ that they think is adequate, at least in some restricted setting. But if this is a solution, then the problem we face is far from a lack of solutions; rather, we have an overabundance of conflicting ones. Kripke’s work alone provides us with uncountably many different extensions for the truth predicate. Even if it so happens that one of these is a conclusive solution, we do not seem to know which one, or why. We should also ask, given that we are faced with many technically elegant but contradictory views, if they are really all addressing the same problem. What we lack is not solutions, but a way to compare and evaluate the many ones we have. (shrink)

Michael Wedin argues against the prevailing notion that Aristotle's views on the nature of reality are fundamentally inconsistent. According to Wedin's new interpretation, the difference between the early theory of the Categories and the later theory of the Metaphysics reflects the fact that Aristotle is engaged in quite different projects in the two works--the earlier focusing on ontology, and the later on explanation.

both the initial justification for adopting it and the justification for retaining it provided by seeming memories. This view captures our intuitions about justification in several cases, while none of the alternative views can.

Despite various attempts to rectify matters, the internalism-externalism (I-E) debate in epistemology remains mired in serious confusion. I present a new account of this debate, one which fits well with entrenched views on the I-E distinction and illuminates the fundamental disagreements at the heart of the debate. Roughly speaking, the I-E debate is over whether or not certain of the necessary conditions of positive epistemic status are internal. But what is the sense of internal here? And of which conditions of (...) which positive epistemic status are we speaking? I argue that an adequate answer to these questions requires reference to what I call the no-defeater condition which is satisfied by a subjects belief B just in case she does not believe that B is defeated. I close by stating succinctly the main positions taken in the I-E debate, identifying the basic points of disagreement and suggesting fruitful courses for future discussion. (shrink)

A bronze statue is a lump of bronze – or so it might appear. But appearances are not always to be trusted, and this one is notoriously problematic. To see why, imagine a bronze statue (perhaps a statue of David) and ask yourself: Which lump of bronze is the statue? Presumably, it is the lump that makes up the statue (or, as we say, the lump that constitutes the statue). After all, why should the statue be any other lump of (...) bronze? But if that is right, if the statue is the lump of bronze that constitutes it, then why can the lump of bronze survive being melted down whereas the statue it constitutes cannot? It seems that in fact the bronze statue is not the lump of bronze that constitutes it, since the statue and the lump of bronze have different persistence conditions. But then is it some other lump of bronze? Is it a lump of bronze at all? These questions are troubling; they appear to have no easy answers. (shrink)

In this provocative book, Michael Tye presents his unique account of the metaphysical foundations of psychological discourse. In place of token identity theory or eliminative materialism, he advocates a generalisation of the adverbial approach to sensory experience, the 'operator theory'. He applies this to the analysis of prepositional attitudes, arguing that mental statements cannot involve reference to mental events or objects and that therefore causal statements about the mental cannot be regarded as asserting relations between events. This adverbial theory (...) has the virtue of being both simple and systematic and is an important contribution to the philosophy of mind. (shrink)

In this paper, I present an Aristotelian solution to the problem of material constitution. The problem of material constitution arises whenever it appears that an object a and an object b share all of the same parts and yet are essentially related to their parts in different ways. (A familiar example: A lump of bronze constitutes a statue of Athena. The lump and the statue share all of the same parts, but it appears that the lump can, whereas the statue (...) cannot, survive radical rearrangements of those parts.) I argue that if we are prepared to follow Aristotle in making a distinction between numerical sameness and identity, we can solve the problem of material constitution without recourse to co-location or contingent identity and without repudiating any of the familiar objects of common sense (such as lumps and statues) or denying that these objects have the essential properties we ordinarily think that they have. (shrink)

This paper argues for the thesis that, roughly put, it is impossible to talk about absolutely everything. To put the thesis more precisely, there is a particular sense in which, as a matter of semantics, quantifiers always range over domains that are in principle extensible, and so cannot count as really being ‘absolutely everything’. The paper presents an argument for this thesis, and considers some important objections to the argument and to the formulation of the thesis. The paper also offers (...) an assessment of just how implausible the thesis really is. It argues that the intuitions against the thesis come down to a few special cases, which can be given special treatment. Finally, the paper considers some metaphysical ideas that might surround the thesis. Particularly, it might be maintained that an important variety of realism is incompatible with the thesis. The paper argues that this is not the case. (shrink)

Michael Walzer; Education, Democratic Citizenship and Multiculturalism, Journal of Philosophy of Education, Volume 29, Issue 2, 30 May 2006, Pages 181–189, http.

Possibility offers a new analysis of the metaphysical concepts of possibility and necessity, one that does not rely on any sort of "possible worlds." The analysis proceeds from an account of the notion of a physical object and from the positing of properties and relations. It is motivated by considerations about how we actually speak of and think of objects. Michael Jubien discusses several closely related topics, including different purported varieties of possible worlds, the doctrine of "essentialism," natural kind (...) terms and alleged examples of necessity a posteriori. The book also offers a new theory of the functioning of proper names, both actual and fictional, and the discussion of natural kind terms and necessity a posteriori depends in part on this theory. (shrink)