Previous studies have shown that children retreat from argument‐structure overgeneralization errors (e.g., *Don’t giggle me) by inferring that frequently encountered verbs are unlikely to be grammatical in unattested constructions, and by making use of syntax‐semantics correspondences (e.g., verbs denoting internally caused actions such as giggling cannot normally be used causatively). The present study tested a new account based on a unitary learning mechanism that combines both of these processes. Seventy‐two participants (ages 5–6, 9–10, and adults) rated overgeneralization errors with higher (...) (*The funny man’s joke giggled Bart) and lower (*The funny man giggled Bart) degrees of direct external causation. The errors with more‐direct causation were rated as less unacceptable than those with less‐direct causation. This finding is consistent with the new account, under which children acquire—in an incremental and probabilistic fashion—the meaning of particular constructions (e.g., transitive causative = direct external causation) and particular verbs, rejecting generalizations where the incompatibility between the two is too great. (shrink)

Scientific endeavor is the pursuit of knowledge with the aim of advancing the welfare of all human beings. This endeavor is built on the ideology of science; thus, society relies on the integrity of the practice of science and of scientists themselves. The responsible conduct of research is the essence of good science; however, many of the pedagogical approaches used to instill integrity in science accentuate the negative rather than exemplify ideal professionalism. This paper makes an argument for the inculcation (...) of the appropriate conduct of research via a positive approach. We address the acclimation to the culture of science that supersedes diverse cultural backgrounds of students. We suggest techniques for the implementation of positive strategies and reinforce the benefit of approaching the teaching of ethical behavior as a competitive advantage. We highlight ways in which this approach can empower the individual scientist and the scientific community as a whole. Transmission of the culture of scientific professionalism formalizes the aims of an ideal scientific professional and encourages assimilation and identification as a member of the scientific profession. We purport that instilling scientific professionalism will spur responsible conduct of research. (shrink)

Our research’s aim is to assess the effect of cultural factors on business ethical decision-making process in a Western cultural context and in a non-Western cultural context. Specifically, this study investigates ethical perceptions, religiosity, personal moral philosophies, corporate ethical values, gender, and ethical intentions of U.S. and Moroccan business managers. The findings demonstrate that significant differences do exist between the two countries in idealism and relativism. Moroccan managers tend to be more idealistic than the U.S. managers. There is a strong (...) positive relationship between religiosity and idealism. There were mixed findings in examining the correlates of religiosity and various components of ethical intentions. Moroccan managers were more homogenous in their corporate ethical values than were the U.S. managers. The results demonstrate that (in general) idealism is a good predictor of ethical intentions and behaviors. Additionally, managers from the two countries differed in the degree of relationship between perceptions and intentions in three of the four scenarios. This study’s results confirm other research findings that, in general, female business managers have higher ethical sensitivity in terms of their ethical judgment than their male counterparts. Managerial implications are also discussed. (shrink)

In all domains of life, transmembrane proteins from the ATP‐binding cassette (ABC) transporter family drive the translocation of diverse substances across lipid bilayers. In pathogenic fungi, the ABC transporters of the pleiotropic drug resistance (PDR) subfamily confer antibiotic resistance and so are of interest as therapeutic targets. They also drive the quest for understanding how ABC transporters can generally accommodate such a wide range of substrates. The Pdr5 transporter from baker's yeast is representative of the PDR group and, ever since (...) its discovery more than 30 years ago, has been the subject of extensive functional analyses. A new perspective of these studies has been recently provided in the framework of the first electron cryo‐microscopy structures of Pdr5, as well as emergent applications of machine learning in the field. Taken together, the old and the new developments have been used to propose a mechanism for the transport process in PDR proteins. This mechanism involves a “flippase” step that moves the substrates from one leaflet of the bilayer to the other, as a central element of cellular efflux. (shrink)

This paper is motivated by the increasing popularity of efficient designs for stated choice experiments. The objective in efficient designs is to create a stated choice experiment that minimizes the standard errors of the estimated parameters. In order to do so, such designs require specifying prior values for the parameters to be estimated. While there is significant literature demonstrating the efficiency improvements of employing efficient designs, the bulk of the literature tests conditions where the priors used to generate the efficient (...) design are assumed to be accurate. However, there is substantially less literature that compares how different design types perform under varying degree of error of the prior. The literature that does exist assumes small fractions are used, which is in contrast to computer-aided surveys that readily allow for large fractions. Further, the results in the literature are abstract in that there is no reference point to provide clear insight on the magnitude of any issue. Our objective is to analyze the robustness of different designs within a typical stated choice experiment context of a trade-off between price and quality. We use as an example transportation mode choice, where the key parameter to estimate is the value of time. Within this context, we test many designs to examine how robust efficient designs are against a misspecification of the prior parameters. The simple mode choice setting allows for insightful visualizations of the designs themselves and also an interpretable reference point for the range in which each design is robust. Not surprisingly, the D-efficient design is most efficient in the region where the true population VOT is near the prior used to generate the design: the prior is $20/h and the efficient range is $10–$30/h. However, the D-efficient design quickly becomes the most inefficient outside of this range, and the estimation significantly degrades above $50/h. The orthogonal and random designs are robust for a much larger range of VOT. The robustness of Bayesian efficient designs varies depending on the variance that the prior assumes. Implementing two-stage designs that first use a small sample to estimate priors are also not robust relative to uninformative designs. Arguably, the random design performs as well as any design, and it will perform even better if data cleaning is done to remove choice tasks where one alternative dominates the other. (shrink)

Ethics, Policy & Environment, Volume 14, Issue 2, Page 231-237, June 2011.

Is a coherent worldview that embraces both classical Christology and modern evolutionary biology possible? This volume explores this fundamental question through an engaged inquiry into key topics, including the Incarnation, the process of evolution, modes of divine action, the nature of rationality, morality, chance and love, and even the meaning of life. Grounded alike in the history and philosophy of science, Christian theology, and the scientific basis for evolutionary biology and genetics, the volume discusses diverse thinkers, both medieval and modern, (...) ranging from Augustine and Aquinas to contemporary voices like Richard Dawkins and Michael Ruse. Aiming to show how a biologically informed Christian worldview is scientifically, theologically, and philosophically viable, it offers important perspectives on the worldview of evolutionary naturalism, a prominent perspective in current science–religion discussions. The authors argue for the intellectual plausibility of a comprehensive worldview perspective that embraces both Christology and evolution biology in intimate relationship. (shrink)

This paper examines the outcomes of Preserving the Past Together, a workshop series designed to build the capacity of local heritage managers to engage in collaborative and community-based approaches to archaeology and historic preservation. Over the past two decades practitioners of these approaches have demonstrated the interpretive, methodological, and ethical value of integrating Indigenous perspectives and methods into the process and practice of heritage management and archaeology. Despite these benefits, few professional resources exist to support the development of collaborative relationships (...) between local heritage managers and Tribal nations. Filling this need, Preserving the Past Together’s interactive workshops and keynote lectures involved participants in a discussion of the central themes in collaborative and Indigenous approaches to archaeology today, highlighting the local challenges and opportunities that exist for archaeologists, heritage managers, and Tribal nations to work together to care for the past. This paper presents an overview of the event series’ goals, the strategies it used to foster collaboration among the diverse stakeholders of the Salish Sea, and the next steps the project’s co-directors are taking to further support communication and collaboration between stewards and stakeholders in the Pacific Northwest. (shrink)

Building on organizational justice research, we extended the study of classroom justice to management education. In the first study, we identified the criteria that business students use to define distributive, procedural, and interactional fairness. In a second study, we found that management students? perceptions of both procedural and interactional fairness were significant and unique predictors of their evaluations of instructional effectiveness. However, procedural justice was the only significant predictor of overall evaluations of the course. Results of this study will aid (...) management educators in implementing procedures and treatment that students perceive as fair and also to serve as ethical role models for managers of the future. (shrink)

Mechanistic models are built using knowledge as the primary information source, with well-established biological and physical laws determining the causal relationships within the model. Once the causal structure of the model is determined, parameters must be defined in order to accurately reproduce relevant data. Determining parameters and their values is particularly challenging in the case of models of pathophysiology, for which data for calibration is sparse. Multiple data sources might be required, and data may not be in a uniform or (...) desirable format. We describe a calibration strategy to address the challenges of scarcity and heterogeneity of calibration data. Our strategy focuses on parameters whose initial values cannot be easily derived from the literature, and our goal is to determine the values of these parameters via calibration with constraints set by relevant data. When combined with a covariance matrix adaptation evolution strategy, this step-by-step approach can be applied to a wide range of biological models. We describe a stepwise, integrative and iterative approach to multiscale mechanistic model calibration, and provide an example of calibrating a pathophysiological lung adenocarcinoma model. Using the approach described here we illustrate the successful calibration of a complex knowledge-based mechanistic model using only the limited heterogeneous datasets publicly available in the literature. (shrink)

Quarantine and spatial distancing measures associated with COVID-19 resulted in substantial changes to individuals’ everyday lives. Prominent among these lifestyle changes was the way in which people interacted with media—including music listening. In this repeated assessment study, we assessed Australian university students’ media use throughout early stages of the COVID-19 pandemic in Australia, and determined whether media use was related to changes in life satisfaction. Participants were asked to complete six online questionnaires, capturing pre- and during-pandemic experiences. The results indicated (...) that media use varied substantially throughout the study period, and at the within-person level, life satisfaction was positively associated with music listening and negatively associated with watching TV/videos/movies. The findings highlight the potential benefits of music listening during COVID-19 and other periods of social isolation. (shrink)

L'année 2006 coïncide avec le sixième centenaire de la mort d'Ibn Khaldûn. Figure marquante et attachante de la culture arabe classique, ce philosophe de l'histoire fut principalement le lecteur critique de phénomènes socio-économiques récurrents et endémiques, qui sont encore, même sous de nouvelles formes, parmi les causes de notre retard historique : segmentarisme et esprit de corps tribal, despotisme, pauvreté et corruption, etc. En tirant les conséquences de son analyse de l'œuvre khaldûnienne, l'auteur pense que le désir de modernité dans (...) le monde arabe d'aujourd'hui a besoin, pour s'exprimer et se réaliser, de la médiation démocratique, entendue dans sa double articulation politico-économique. Cette médiation ne permet pas seulement de faire l'histoire de l'exploitation de l'homme par l'homme, de ses effets et ses retombées, mais aussi de penser sa fin. Par le seul fait que l'œuvre khaldûniennne balise de bout en bout le parcours du Maghreb précolonial, elle mérite notre sollicitation et notre attention. Et même si par bonheur cette région parvenait à rompre effectivement avec sa genèse médiévale, ladite œuvre restera pour les historiens et les penseurs une source d'information et de méditation intarissable de premier plan. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Hume on Space (and Time) BEN MIJUSKOVIC HUME'S LABYRINTHINE ANALYSES of our ideas of space and time, textually occuring so early in the Treatise, 1clearly testify to his conviction of their central role in the physical sciences, then making such fantastic progress. Furthermore, quite early in the Treatise, Hume indicates his ambition to effect a revolution in the mental sciences comparable to the one Newton had achieved in the (...) physical disciplines, through the latter's conception of the force and effects of gravity. Accordingly, Hume regards the three principles or laws of the association of ideas as a "kind of ATTRACTION, which in the mental world will be found to have as extraordinary effects as in the natural" (T, 12-13). In pursuit of his investigations Hume commences, in the first part of the Treatise, by insisting on the principle that all our simple ideas are derived from simple impressions and that impressions always precede their correspondent ideas (T, 4, 7). This being firmly established, Hume nevertheless immediately proceeds in the very next part of the work to declare, paradoxically enough, that our ideas of space and time are complex ideas that lie beyond the nature of each and all of our simple impressions. Differently put, Hume is insisting that our ideas of space and time, unlike our idea of, say, a shade of blue, are not derived unproblematically from a precedent, simple mental impression (or physiological sensation, ~ la Locke). Thus, according to Hume, our idea of space is not sensationally given; it is not traceable to an antecedent extended impression as our idea of blue is derived from a precedent impression of blue. Hume's insistence that our conception of space is nonsensational has perplexed competent commentators on Hume. Consequently, even so able an interpreteter as Kemp Smith has been puzzled "why it was that [Hume] did not take the more easy line of allowing 'extensity' to the sensations of sight and touch. ''2 Or again, "How is it that [Hume] has not taken what would seem to be for him the easier and more obvious course, at least as regards space--the course usually taken by those who hold a sensationalist theory of knowledge--that extensity is a feature of certain of our sensations (those given through the senses of touch and sight), and in consequence sensibly imaged?" (PDH, 280). Of this simpler solution both Hobbes (Leviathan, Pt. I, 1; De Corpore, Pt. II, 7, 8) and Locke (Essay, II, 8) had availed themselves prior to Hume. Hence, Kemp Smith has found the section to be tough going indeed and has contented himself, to a great extent, in simply offering a number of historical appendices, suggesting lines of influence on Hume, through passages discovered in the works of Pierre Bayle, Nicholas de Malezieu, and Isaac Barrow. Now, without denying that Hume studied and was influenced in part by the ' A Treatise of Hurnan Nature, ed. L. A. Selby-Bigge (Oxford, 1888); hereafter cited as T. 2 The Philosophy of David Hume (New York, 1964), p. 277; hereafter cited as PDH. [3871 388 HISTORY OF PHILOSOPHY thinking of these authors (as well as by Francis Hutcheson), I wish to take up and develop in this paper a "historical" suggestion first offered by a student of Kemp Smith's, Charles Hendel; and I shall extend Hendel's point and try to argue a "theoretic" one, namely, that Hume's phenomenalism in the section devoted to space and time is derived from, and closely akin to, a form of Leibnizian idealism. In 1925, Hendel argued that Hume was directly influenced by the Leibniz-Clarke debate over the ontological and epistemological status of space and time; and he held that for Hume space and time, as appearances, were ultimately grounded in the associative power of the imagination.' Thirty years later, in a second edition, Hendel disavowed his earlier claim concerning the imagination and avoided discussion of his prior view that Hume was influenced by the Leibniz-Clarke correspondence (1963 edition, pp. 501, 503). In Hume's Philosophy of Human Nature, which first appeared in 1932 (reissued by Archon, 1967; see pp. 64-65, 67, 73, 77), John Laird also intimated that... (shrink)

The ‘consensus’ model of public reason, associated with John Rawls’s political liberalism, has been criticised for excluding certain reasons from receiving consideration where the justification of the constitutional essentials is concerned. One limitation of these criticisms is that they typically focus on the exclusion of reasons political liberals are committed to excluding, notably reasons based on religious and comprehensive views. I argue that public reason excludes some reasons, central to the interests of many oppressed groups, that public reason advocates will (...) agree should not be excluded.L’idée de raison publique comme «consensus», associée au libéralisme politique de John Rawls, a été attaquée du fait de sa supposée incapacité à permettre la prise en compte de certaines raisons dans les cas où la substance même de la constitution est en question. Une limitation de ces critiques est qu’elles se concentrent habituellement sur l’exclusion de ces raisons que les libéraux eux-mêmes s’efforcent d’exclure, en particulier des raisons fondées sur des vues globales ou religieuses. Je défends l’idée selon laquelle la raison publique exclut de fait certaines raisons, essentielles aux intérêts de nombreux groupes opprimés, que les tenants de la raison publique eux-mêmes considèreraient ne pas devoir être exclues. (shrink)

Joseph Ben-David (1920-1986) fut un des sociologues des sciences les plus innovateurs et les plus en vue des années soixante et soixante-dix. Travaillant dans le cadre des théories sociologiques de Max Weber, Talcott Parsons et Robert Kmerton, il élabora dans ses ouvrages et nombreux articles une théorie sociologique originale du développement scientifique. Par sa démarche diachronique, il se démarque des sociologues des sciences de l'école fonctionnaliste ; par sa perspective sociologique, il définit des nouvelles problématiques qui viennent s'ajouter à celles (...) des historiens des sciences travaillant dans une optique " internaliste ". Dans le présent ouvrage ont été réunis et traduits les articles les plus importants de Ben-David, qui, ensemble, dessinent les contours d'une sociologie historique des sciences. Par son pouvoir explicatif, cette théorie est à même d'enrichir la pratique de l'historien des sciences, tandis que, par sa réaffirmation des vertus éthiques des rôles sociaux du savant et de l'Université, elle est d'une grande actualité pour les débats sur l'enseignement supérieur en France. (shrink)

Background Clients are invited to play a role in decisions about their care. Collaborative deliberation comprises constructive engagement, recognition of alternative actions, comparative learning, construction and elicitation of preferences and preference integration. Collaborative deliberation between clients and professionals is a process that requires an interest in each other, sharing of views on alternatives and preferences and integrating into decisions. The aim is to gain insight into collaborative deliberation in consultations and the clients’ perception of arranging long-term care. Design A descriptive (...) qualitative study to explore collaborative deliberation in consultations between clients and professionals. Six organisations providing long-term care were included. Data collection of nine clients involved observations of consultation with field notes and audio-records, interviews with clients and professionals shortly and 3–6 months after the consultation and questionnaires to collect background information. The data were analysed by deductive content analysis. Findings Constructive engagement was visible in all consultations. Clients and professionals showed respect, empathy and curiosity towards each other. In most consultations, two or more alternative actions are recognised and discussed. Comparative learning appears to be two sided, the client and the professional learn from each other's knowledge and experiences. Construction and elicitation of preference, and preference integration, seems to be present, but difficult to recognise in all consultations. Discussion/conclusion Although all propositions could be identified, there seems room for improvement in preference elicitation and integration of these preferences in the discussions on courses of action. Assistance seems needed with preference elicitation, both for the clients and for the professional. (shrink)

Language and mind, by N. Chomsky.--Some reflections on the nature of consciousness, by B. A. Farrell.--The two faces of perception, by J. R. Platt.--Building better brains, by R. W. Gerard.--The nature of psychological change and its relation to cultural change, by L. S. Kubie.--Alienation and autonomy, by B. Bettelheim.--Darwin versus Copernicus, by T. Dobzhansky.--Speculations on the problem of man's coming to the ground, by S. L. Washburn.--Revolution and development, by K. E. Boulding.--The peasant revolt of our times, by W. H. (...) McNeill.--Triumph and failure in ancient Egypt, by J. A. Wilson.--The tyranny of progress, by R. Gomer.--Man and mankind in the development of culture and the humanities, by R. McKeon. (shrink)

Using the Job Demands-Resources model literature and the life-span theory as scholarly frameworks, we examined the effects of job demands and job resources as mediators in the relationship between bundles of used HRM practices and employee outcomes. In addition, we tested for age differences in our research model. Findings confirmed the hypothesized original 2-factor structure representing maintenance and development HRM practices. Structural Equation Modeling analyses showed that the maintenance HRM bundle related directly and negatively to employee outcomes, without moderating effects (...) of age. However, job resources appeared to mediate this relationship in a positive way as it also did for the development HRM bundle. Whereas this study showed the ‘driving power’ of the actual use of HRM bundles through job resources, regardless of the employee’s age, this study also suggests a ‘dark side’ of HRM. In particular, we found that development HRM bundles may also increase job demands, which, in turn, may result in lower levels of beneficial employee outcomes. These empirical outcomes demonstrate the strength of the driving power eliciting from job resources preceded by any HRM bundle. Moreover, this effect appears to apply to employees of all ages. Our moderated-mediation model appeared robust for several control variables. Overall, this study provides an extension of the well-known Job Demands-Resources model by including maintenance and development bundles of HRM practices used by employees that have a differential effect on job demands and job resources which in turn have an impact on employee outcomes. (shrink)