The relevance of nonlinear dynamics to calcium metabolism led us to reevaluate the role of Ca-regulating hormones in Ca homeostasis. We suggest that, firstly, the main Ca metabolic functions in rat-bone and gut - are organized as dynamic entities able to generate various temporal expressions, including self-oscillating patterns and, secondly, Ca homeostasis results from interaction between both metabolic and hormonal oscillators. Following this schema, a major role for the hormonal system, with its circadian pattern, could be to act directly on (...) metabolic functions or indirectly through feeding behaviour, in order to optimize, coordinate and synchronize the Ca fluxes at ECF level. (shrink)

Two experiments used eyetracking during reading to examine the processing of the matrix verb following object and subject relative clauses. The experiments show that the processing of the matrix verb following an object relative is indeed slowed compared to the processing of the same verb following a subject relative. However, this difficulty is entirely eliminated if additional material intervenes between the object gap and the matrix verb. An explanation in terms of spillover processing is ruled out, suggesting that it is (...) the gap-matrix verb sequence that is itself responsible for the difficulty. We consider two accounts of this difficulty, one emphasizing the potential difficulty of rapidly switching between the sentential subject's thematic or syntactic role in the embedded clause and its role in the matrix clause, and one emphasizing the potential difficulty of performing two demanding memory retrievals in rapid succession. The present experiments also closely replicate the previous findings from eyetracking that the noun phrase and the verb within an object relative are both loci of processing difficulty, but that the former induces substantially greater difficulty. (shrink)

The temporal behaviour of the nonlinear compartmental model we have developed for rat calcium metabolism is discussed with respect to the theoretical properties of the self-oscillating autocatalytic subunit around which the model is constructed. Depending on the approximations made, this subunit is described by a minimal two-variable model, SU2, or by a three-variable one, SU3. The diversity of the theoretical dynamic behaviours possible with SU2 is greatly increased with SU3. But the identification of SU3 parameter values in three different experimental (...) situations reveals that biological constraints efficiently preserve a simple circadian rhythm for bone metabolism. This analysis indicates the significant contribution of the available bone crystal pool to the dynamic organization of this tissue, and hence to extracellular calcium homeostasis. (shrink)

The ?West? is inclined to blame Asian countries, especially China, for its disrespect of human rights without looking at it's own record of human rights violations! This makes a fair dialogue very difficult till improbable. Social work on the international level can't avoid this dialogue if it wants to live up to its internationally consensual documents which all refer to human rights. The thesis of this article is, that it will only succeed, if it clarifies some philosophical and ethical premisses (...) of so-called ?western? and ?oriental/asian? thinking. Thus, the article tries to show that concepts of ?holism?, ?atomism/individualism? and ?systemic thinking? might be helpful for a ?rejonder? and discussion platform for the analysis of different modes of thinking about ethical issues. A systemic approach tries to avoid the problematic and combine the positive aspects of individualistic and holistic approaches. An example for this combination is the ?Asian Human Rights Charter: A People's Charter? of 1998 which doesn't divide the freedom and participatory versus social rights, a divide which is typical ? and problematic ? for the western version. (shrink)

The concept of something runs like a red thread through Husserl's explanations of the phenomenological theory of intentionality. "Something" is what we mean even when we use fictional and contradictory expressions. In the words of Emile Benveniste, how can this "something" be demarcated from language? In the search for a linguistically adequate understanding of this concept, topics as diverse as Augustine's theory of language, Franz Bopp's comparative grammar, text linguistics, or Heidegger's reading of the modistic treatise are treated within the (...) framework of comparative studies. It is, as the phenomenological analysis of empty names or inner monologue shows, in particular situations of speaking that the concept of something and thus the meaning-bearing function of linguistic expressions comes into consciousness. (shrink)

A nonlinear two-variable reaction-diffusion model of bone mineral metabolism, built from an overall self-oscillatory compartmental model of calcium metabolism in vivo, has been studied for its ability to generate spatial and spatio-temporal self-organizations in a two-dimensional space. Analytical and numerical results confirm the theoretical properties previously described for this kind of model. In particular, it is shown that, for a given set of reactional parameter values and certain values of the ratio of the two diffusion coefficients, there exists a set (...) of unstable wavenumbers leading spontaneously to the development, from the homogeneous steady state, of either different types of stationary spatial patterns (hexagonal, striped and re-entrant hexagonal patterns) or more or less complex spatio-temporal expressions. We discuss the relevance of analogies established between some spatial or spatio-temporal structures predicted by the model and some peculiar features of the primary bone trabecular architecture which appear during embryonic ossification. (shrink)

Изложено понимание рассуждения как метода рационального познания, рассмотрены его разновидности: аргументативные, интерпретативные, прогностические, квалификационные и вычислительные. Для аспирантов и соискателей.

Thomas Kuhn's The Structure of Scientific Revolutions has sold more than one million copies since its publication in 1962, is one of the most cited academic books of all time, and continues to be read and studied today. This volume of new essays evaluates the significance of Kuhn's classic book in its changing historical context, including its initial reception and its lasting effects. The essays explore the range of ideas which Kuhn made popular with his influential philosophy of science, including (...) paradigms, normal science, paradigm changes, scientific revolutions, and incommensurability; and they also look at less-studied themes in his work, including scientific measurement, science education, and science textbooks. Drawing on the latest scholarship as well as unpublished material in the Thomas Kuhn Archives at MIT, this volume offers a comprehensive way into Kuhn's philosophy and demonstrates the continuing relevance of his ideas for our understanding of science. (shrink)

In Nicolaus Cusanus on Faith and the Intellect: A Case Study in 15th-Century Fides-Ratio Controversy, K.M. Ziebart presents an account of the Cusan epistemology as a fascinating late-medieval attempt to definitively harmonize faith and reason.

This paper offers a review of the catalogue composed by Myriam Vogelaar of one of the largest and most important collections of Fight Books and fencing manuals in the field of Historical European Martial Arts Studies (HEMAS). The Mokken Collection is named after Wiebe Mokken, the man who meticulously built it up over the past decades in Amsterdam. The book also highlights the glaring lack of contemporary knowlegde about other major historical fencing-related collections, like Gotti’s spectacular private collection held at (...) the Museo dell Arte Marziale in Brescia, Italy. Others, such as the Corble collection at the KU Leuven Libraries, recently published their catalogue on line. This catalogue thus constitutes an important milestone for this exciting and still relatively new subdomain in the field of European cultural studies, by making accessible one of the most important collections of source materials dedicated to it. (shrink)

At the beginning of the study of physical phenomena, the idea of "force" was widely used to explain the non-stationarity of observed phenomena, such as the movement of bodies. However, as mechanics and physical theories developed, the force notions gained own formal definitions and names, without the use of the term "force". So, the concept of kinetic energy arose instead of "vis viva", and "current" instead of "current strength" ets. Additionally, a number of new physical theories have been formulated without (...) the use of force concept. As a result, different types of forces have gradually been replaced by other more important concepts, such as energy and action, which are closely linked to fundamental physical principles. It is interesting to note that the general trend in the development of civilizations has been a shift from unrestricted power (expressed in the thesis "might makes right") to its subordination and incorporation into a legal framework. This is similar to the evolution of physics, which has seen the notion of force become eliminated or subordinated to more general principles and laws. (shrink)