How chromatin bridges are detected by the abscission checkpoint during mammalian cell division is unknown. Here, we discuss recent findings from our lab showing that the DNA topoisomerase IIα (Top2α) enzyme binds to catenated (“knotted”) DNA next to the midbody and forms abortive Top2‐DNA cleavage complexes (Top2ccs) on chromatin bridges. Top2ccs are then processed by the proteasome to promote localization of the DNA damage sensor protein Rad17 to Top2‐generated double‐strand DNA ends on DNA knots. In turn, Rad17 promotes local recruitment (...) of the MRN protein complex and downstream ATM‐Chk2‐INCENP signaling to delay abscission and prevent chromatin bridge breakage in cytokinesis. (shrink)

The concept of ?ethical consumer behavior? has gained significant attention among practitioners and academic researchers, generating increasing but disjointed knowledge on the topic. By analyzing the empirical research on ethical consumer behavior, this article provides researchers with a map to guide future research. In total, we review 80 studies. The main contributions of the article include the identification of the main trends in the ethical consumer literature and the conceptualization of ethical consumer behavior. In addition, several areas for future research (...) are proposed and discussed. (shrink)

Abstract In this paper, we show that Greek distinguishes empirically ability as a precondition for action, and ability as initiating and sustaining force for action. In this latter case, the ability verb behaves like an action verb, and the sentence has the logical form of a causative structure φ CAUSE [BECOME ψ] (Dowty 1979). The distinction between ability as potential for action and ability as action itself has a venerable tradition that goes back to Aristotle, and is recently implied in (...) a number of analyses (Mari and Martin 2007, 2009, Thomason 2005). We show first that the phenomenon is not just aspectual ( pace Bhatt 1999, Hacquard 2006, 2009, Pinon 2003): actualized ability emerges with the ability verb also with imperfective aspect and present tense. They key, we argue is causation, which triggers a shift from pure ability, to ability as force (in the sense of Copley and Harley 2010, i.e. as action initiating energy). In Greek, the action reading of the ability modal comes about in an apparent co-ordinate causative structure, where the two clauses are connected with conjunction ke ‘and’— a pattern that we find also in other languages, including English, at least with some action verbs such as try, allow . Our analysis implies a meaning of ability richer than mere possibility ( pace Hacquard); and, by capitalizing on the causative meaning and the presence of force in causative structures, our analysis enables a principled explanation of the shift to action-ability without positing ambiguity for the ability verb ( pace Bhatt 1999). (shrink)

To what extent can business ethics be hospitable to Levinasian ethics? This paper raises questions about how business ethics relates to its guests, in this case the guest called Levinas; the idea of introducing or inviting the work of an author into a field, as its guest, is by no means a simple problem of transference. For Jacques Derrida, there is hospitality only when the stranger's introduction to our home is totally unconditional. Such a conceptualization of hospitality becomes even more (...) demanding when the stranger that is near our home is an ethics also demanding hospitality, such as the ethics proposed by Levinas. An invitation puts in place particular circumstances that allow only for an arrival of the one invited. These conditions precede the so-called stranger, thereby predetermining the route to be taken, the destination to be reached and the correct manner of self-presentation. An invitation already reduces the Other to that which is expected by the inviter, that is to the Same. The hospitality of the field of business ethics becomes an endorsement of a particular version of the stranger, therefore recognizable by the field. Perhaps conceptualizing Levinasian ethics as an ethics that cannot be invited might protect it from procedures that reduce the strangeness of the stranger, making it knowable. That is the argument presented in this paper. (shrink)

In this paper we suggest that there is a need to examine what is meant by “context” in Social Psychology and present an example of how to place identity in its social and institutional context. Taking the case of British naturalisation, the process whereby migrants become citizens, we show that the identity of naturalised citizens is defined by common-sense ideas about Britishness and by immigration policies. An analysis of policy documents on “earned citizenship” and interviews with naturalised citizens shows that (...) the distinction between “elite” and “non-elite” migrants is evident in both the “reified” sphere of policy and the “common sense” sphere of everyday identity construction. While social representations embedded in lay experience construct ethno-cultural similarity and difference, immigration policies engage in an institutionalised positioning process by determining migrants' rights of mobility. These spheres of knowledge and practice are not disconnected as these two levels of “managing otherness” overlap—it is the poorer, less skilled migrants, originating outside the West who epitomise difference (within a consensual sphere) and have less freedom of mobility (within a reified sphere). We show that the context of identity should be understood as simultaneously psychological and political. (shrink)

My aim in this paper is to demonstrate the relevance of the Aristotelian notion of civic friendship to contemporary political discussion by arguing that it can function as a social good. Contrary to some dominant interpretations of the ancient conception of friendship according to which it can only be understood as an obligatory reciprocity, I argue that friendship between fellow citizens is important because it contributes to the unity of both state and community by transmitting feelings of intimacy and solidarity. (...) In that sense, it can be understood as an important relationship predicated on affection and generosity, virtues lacking from both contemporary politics and society that seem to be merely dominated by Post-Enlightenment ideals. For Aristotle, friendship is important for society because it generates concord, articulating thus a basis for social unity and political agreement. (shrink)

While downsizing has been widely studied, its connection to firm ownership status and the reasons behind it are missing from extant research. We explore the relationship between downsizing and family ownership status among Fortune 500 firms. We␣propose that family firms downsize less than non-family firms, irrespective of performance, because their relationship with employees is based on normative commitments rather than financial performance alone. We suggest that their actions are related to employee- and community-friendly policies. We find that family businesses do (...) downsize less irrespective of financial performance considerations. However, their actions are not related to their employee- or community-friendly practices. The results raise issues related to the motivations of large multinationals to␣downsize and the drivers of their stakeholder management practices. (shrink)

This paper considers different subjective measures of conscious and unconscious knowledge in a concept formation paradigm. In particular, free verbal reports are compared with two subjective measures, the zero-correlation and the guessing criteria, based on trial-by-trial confidence ratings (a type of on-line verbal report). Despite the fact that free verbal reports are frequently dismissed as being insensitive measures of conscious knowledge, a considerable bulk of research on implicit learning has traditionally relied on this measure of consciousness, because it is widely (...) regarded as almost self-evident that the content of any conscious state that is intentional and conceptual can be expressed verbally. However, we found that the most recently developed subjective measures based on trial-by-trial confidence ratings provided a more sensitive measure of conscious and unconscious knowledge than free verbal reports. In a complementary way, the qualitative pattern of the free report and the confidence measures were similar, providing further evidence for the validity of the latter. (shrink)

The purpose of this article is to explore the concept of rhythm as enabling relations and thus as an appropriate mode of analysis for digital sound art installation. In particular, the article argues for a rhythmanalysis of the sonic event as a ‘vibrating sensation’ (Deleuze and Guattari) that incorporates the virtual without necessarily actualizing it. Picking up on notions such as rhythm, time, affect, and event, particularly through their discussion in relation to Susanne Langer’s work, I argue for the consideration (...) of the sonic event as an instance of a different kind of temporality subsisting underneath clock-time and sense perception. Ultimately, and this is the position of this essay, an investigation into experimental projects that interweave digital, sound, and aesthetic dimensions enables the articulation of a rhythmic time that helps account for the unknown, indeterminate, and unintentional forces immanent to the sonic. (shrink)

This book contributes to the 'rehabilitation' of Plutarch as a philosopher by focusing on an important aspect of his philosophical self: his work as a teacher, interpreter, and, eventually, historian of philosophy.

The present experiment investigated the development of implicit and explicit knowledge during concept learning. According to Cleeremans and Jiménez , the content of a representation can be conscious only when the representation is of a sufficiently good quality; on this theory, increasing explicit and decreasing implicit knowledge might be expected with training. The view that implicit knowledge arises from compilation of explicit knowledge makes the opposite prediction. The present research tested these possibilities using subjective measures based on confidence ratings. One (...) group of participants was presented with blocks of category exemplars that activated prior knowledge, whereas another group was presented with blocks of categories that did not elicit any useful prior knowledge. The results showed that, irrespective of the knowledge group participants were allocated to, explicit knowledge increased over the course of learning, whereas implicit knowledge either stayed the same or decreased, consistent with Cleeremans and Jiménez’s prediction. (shrink)

There are several possible ways for investigating the creative process in musical composition in order to induce certain assumptions about the nature of the compositional experience that may provide a certain philosophical framework for shaping compositional experiences in music educational settings at all levels. By taking an approach mainly based on writings and interviews of twentieth and twenty-first century composers, such as Boulez, Ferneyhough, Foss, Ligeti, Xenakis, Reich, Reynolds, Schoenberg, Stockhausen, and Varèse, among others, Eleni Lapidaki illustrates certain parameters (...) about their actual compositional process. Implications for music education are suggested for immersing student composers in learning experiences that respect their intuitions, search for their individuality, and place emphasis on innovation and creative freedom as inseparable from expression in their compositions. (shrink)

Ambient Intelligence provides the potential for vast and varied applications, bringing with it both promise and peril. The development of Ambient Intelligence applications poses a number of ethical and legal concerns. Mobile devices are increasingly evolving into tools to orientate in and interact with the environment, thus introducing a user-centric approach to Ambient Intelligence. The MINAmI (Micro-Nano integrated platform for transverse Ambient Intelligence applications) FP6 research project aims at creating core technologies for mobile device based Ambient Intelligence services. In this (...) paper we assess five scenarios that demonstrate forthcoming MINAmI-based applications focusing on healthcare, assistive technology, homecare, and everyday life in general. A legal and ethical analysis of the scenarios is conducted, which reveals various conflicting interests. The paper concludes with some thoughts on drafting ethical guidelines for Ambient Intelligence applications. (shrink)

In the context of the growing popularity of the ethical consumer movement and the appearance of different types of ethical collective communities, the current article explores the meanings drawn from the participation in Responsible Consumption Cooperatives. In existing research, the overriding focus has been on examining individual ethical consumer behaviour at the expense of advancing our understanding of how ethical consumers behave collectively. Hence, this article examines the meanings derived from participating in ethical consumer groups. A qualitative multi-method approach is (...) adopted to increase the validity of findings. This includes focus groups, in-depth interviews, observation and document analysis. Results show that ethical consumption in a group project offers a greater sense of effectiveness and control when compared to individual actions. Furthermore, these groups facilitate the creation of a social circle and encourage new learning as a result of the social interaction that takes place in the ethical community of the cooperative. (shrink)

The paper focuses on the rivalry between philosophical excellence and Olympic prestige. Plato has philosophers quarrel not only with poets but also with Olympic victors. Epictetus will follow suit. Not sharing Plato's notion of philosophical excellence, Epictetus' Stoic sage rivals not only the Olympic athletes but classical philosophy itself.

Abstract:The focus of this paper is on managed relocations and endangered wild species. The main argument is that managed relocations should be a viable policy option in the toolbox of conservation management despite any ecological risks. This argument is defended on the basis of recent research that demonstrates that not all alien species are invasive species, and that not all invasive species have negative ecological impacts. In other words, a nuanced case-by-case approach is needed. This argument is presented within the (...) context of the Bramble Cay Melomys, a rat-like creature and the first mammal to become extinct as a result of anthropogenic climate change. A secondary objective of this paper is to explore some of the future economic and policy challenges likely to face managed relocations. (shrink)

Cognitive approaches to early medieval texts have tended to focus on the mind in isolation. By examining the interplay between mental and physical acts deployed in Old English poetry and prose, this study identifies new patterns and offers new perspectives. In these texts, the performance of right or wrong action is not linked to natural inclination dictated by birth; it is the fruit of right or wrong thinking. The mind consciously directed and controlled is open to external influences, both human (...) and diabolical. This struggle to produce right thought and action reflects an emerging democratization of heroism that crosses societal and gender boundaries, becoming intertwined with socio-political, soteriological, and cultural meaning. In a study of influential prose texts, including the Alfredian translations and the sermons of Ælfric, alongside close readings of three poems from different genres – The Seafarer, The Battle of Maldon, and Juliana –, Ponirakis demonstrates how early medieval authors create patterns of interaction between the mental and the physical. These provide hidden keys to meaning which, once found, unlock new readings of much studied texts. In addition, these patterns of balance, distribution, and opposition, reveal a startling similarity of approach across genre and form, taking the discussion of the early medieval conception of the mind, soul, and emotion, not to mention conventional generic divisions, onto new ground. (shrink)

Eleni Panagiotarakou | : The focus of this paper is on the “right to place” as a political theory of wild animal rights. Out of the debate between terrestrial cosmopolitans inspired by Kant and Arendt and rooted cosmopolitan animal right theorists, the right to place emerges from the fold of rooted cosmopolitanism in tandem with environmental and ecological principles. Contrary to terrestrial cosmopolitans—who favour extending citizenship rights to wild animals and advocate at the same time large-scale humanitarian interventions and (...) unrestricted geographical mobility—I argue that the well-being of wild animals is best served by the right to place theory on account of its sovereignty model. The right to place theory advocates human non-interference in wildlife communities, opposing even humanitarian interventions, which carry the risk of unintended consequences. The right to place theory, with its emphasis on territorial sovereignty, bases its opposition to unrestricted geographical mobility on two considerations: the non-generalist nature of many species and the potential for abuse via human encroachment. In a broader context, the advantage of the right to place theory lies in its implicit environmental demands: human population control and sustainable lifestyles. | : Le présent article porte principalement sur le « droit territorial » en tant que théorie politique des droits des animaux sauvages. Issu du débat entre théoriciens cosmopolitistes du droit animal, soit terrestres inspirés par Kant et Arendt, soit enracinés, le droit territorial trouve ses sources dans le cosmopolitisme enraciné qui va de concert avec certains principes environnementaux et écologiques. Contrairement aux cosmopolitistes terrestres, qui préconisent d’étendre les droits de citoyenneté aux animaux sauvages tout en défendant les interventions humanitaires à grande échelle et la mobilité géographique illimitée, j’estime que la théorie du droit territorial est davantage en mesure d’assurer le bien-être des animaux sauvages, grâce à son modèle basé sur la souveraineté. La théorie du droit territorial préconise la non-ingérence dans les communautés fauniques, allant jusqu’à s’opposer aux interventions humanitaires, qui risquent de provoquer des conséquences non désirées. Cette théorie, en mettant l’accent sur la souveraineté territoriale, base son opposition à la mobilité géographique illimitée sur deux considérations : le caractère non généraliste de bon nombre d’espèces, et le risque de mauvais traitements par empiètement humain. Dans un contexte plus large, l’intérêt de la théorie du droit territorial réside dans ses exigences environnementales implicites : le contrôle de la population humaine et l’adoption de modes de vie durables. (shrink)

This paper aims to reevaluate Aristotelian political theory from an egalitarian perspective and to pinpoint its legacy and relevance to contemporary political theory, demonstrating its importance for contemporary liberal democracies in a changing world, suggesting a new critique of liberal and neoliberal political theory and practice, and especially the improvement of our notion of the modern liberal-democratic state, since most contemporary representative liberal democracies fail to take into account the public interest of the many and do very little in order (...) to advance it. The paper will focus on key aspects of Aristotle’s thought, such as his notions of justice (δικαιοσύνη/dikaiosunē and ἁπλῶς δίκαιον/aplōs dikaion), concord (ὁμόμοια/homonoia), friendship (φιλία/philia) and the art of ruling (τέχνη τοῦ ἄρχειν/technē tou archein), arguing that Aristotle’s theory requires us to have concern for our fellow citizens; ‘concern for others’ as opposed to the mere ‘respect for others’ that contemporary neo-Kantian liberalism advocates . Hence, I will examine these aspects of Aristotle’s philosophy that have not so far been adequately discussed, in relation to his conception of the ‘common or public interest’ (τὸ κοινῇ συμφέρον/to koinē sympheron) which is essential in order to understand the Aristotelian vision for ‘the art of politics’ (τέχνη τοῦ ἄρχειν) which should always aim towards the interest of the many, i.e., the people (πλῆθος/plēthos). (shrink)

In recent years, much discussion has taken place regarding the social role of firms and their responsibilities to society. In this context, the role of universities is crucial, as it may shape management students’ attitudes and provide them with the necessary knowledge, skills and critical analysis to make decisions as consumers and future professionals. We emphasise that universities are multi-level learning environments, so there is a need to look beyond formal curricular content and pay more attention to implicit dimensions of (...) the learning process in order to create significant learning. With this in mind, we propose an integrative and holistic approach to guide the integration of ethics, corporate social responsibility and sustainability in management education that aims to improve students’ knowledge and attitudes. In this model, we consider three interdependent levels of analysis–the institutional level, the curricular level and the instrumental level–which together produce a leverage effect on student learning. For each level, we identify the main issues and aspects that need to be considered, based on an extensive literature review in this field. (shrink)

In this paper I examine which is the most appropriate moral theory for dealing with disaster bioethics contexts. It is pointed out that, contrary to what is usually believed, moral theories of right action cannot actually guide us in such difficult situations. Instead, it is claimed that a virtue ethics theory of an Aristotelian version, which gives emphasis not only on the virtuous person but also on the relevant developmental process of becoming virtuous, can provide us with the right theoretical (...) framework for coping with the problems which the victims of such disastrous situations face. (shrink)

Name der Zeitschrift: Semiotica Jahrgang: 2017 Heft: 214 Seiten: 307-329.

Cet article porte principalement sur deux types d’inscriptions dédicatoires, particulièrement liés au culte de Sarapis et d’Isis: les dédicaces doubles et celles en hyper. Les deux types associent dans un seul rituel le couple divin (Sarapis et Isis) et le couple royal (le roi régnant et la reine), invoquant des parallélismes et d’éventuelles identifications entre les deux. Textes simples, rapidement devenus communs et standardisés, ils constituent une source précieuse pour l’histoire ptolémaïque politique et religieuse (en particulier pour le développement du (...) culte royal et dynastique), tout en révélant la mentalité des fidèles entre le iiie siècle av. J.-C. et la fin de l’époque ptolémaïque. (shrink)

The aim of this paper is to highlight the "sacred" and "secular" character of the Xesyrtos or Gikna dance in the community of Asvestades in Thrace in Greece. In particular, this paper intends to highlight the difference between the "sacred" and the "secular" and the way this dichotomy is reflected in the dance under study. Data was gathered through the ethnographic method. The sacred/secular dichotomy, as proposed in Leach's (1976) theoretical model, is used to analyze the data. Further, Laban's notation (...) system (Hutchinson, 2005; Koutsouba, 2005), was used to record the choreographic compositions of Xesyrtos or Gikna dance, while for the analysis of their structure and form, as well as their codification, the structural-morphological and typological method of analysis was applied. Finally, for the presentation and interpretation of the data, Geertz’s model of "thick description" (2003) was adopted. From the data analysis it was found that the Xesyrtos and Gikna dances are danced in exactly the same way, but are clearly separated and demarcated based on the intentions of the community residents related to the performed function of the dance event. (shrink)

Dans le cadre des études héraclitéennes, la compréhension des termes de logos et de physis constitue un problème en soi, compte tenu de l’équivocité dont ils sont porteurs déjà depuis l’antiquité. À travers son dialogue avec Héraclite, Heidegger entend revenir à l’origine de ces mots en vue de mettre en lumière les fondements de la philosophie occidentale. Il relève ainsi le sens originel du logos, comme « recueillement », dans le sens de « recollection », et de la physis, en (...) tant qu’elle désigne l’épanouissement de tout ce qui apparaît. Le logos héraclitéen, avant de signifier raison ou discours, revêt la signification de ce qui rassemble et maintient dans son unité ce qui apparaît en s’épanouissant, la totalité de ce qui est, qu’est la physis. De sorte que le logos, en tant que l’unité originaire de la totalité de l’étant, s’identifie avec la physis. C’est cette identification qui permet à Heidegger de poser à nouveaux frais la question du sens de l’être. (shrink)

Shared Content as Speaker Meaning Cappelen and Lepore have recently emphasised the significance of a minimal notion of perfectly shared content for pragmatic theories. This paper argues for a similar notion, but assumes that a satisfactory defence cannot be achieved along the lines of the existing debate between Minimalism and Contextualism. Rather, it is necessary to consistently distinguish two functional domains: the subjective processing domain and the interpersonal domain of communication, each with its own kind of utterance meaning. I will (...) argue that it is the mutually recognised content of the speaker's overt commitment that should be identified as ‘speaker meaning’. Diverging from the Gricean tradition, it is conventionally restricted, but genuinely pragmatic. Functional considerations show that it is, moreover, unnecessary to include further elements in ‘speaker meaning’. The distinction between two notions of utterance meaning with very different characteristics allows us to integrate the assumption of perfect sharing, which explains people's trust in communication, and the subjectivity of the hearer's inferences into a coherent and powerful model. (shrink)

The present paper addresses Aeschylus, and the way he wanted to be remembered by his fellow Athenians and the other Greeks. Having lived from 525/524 until 456/455 BCE, Aeschylus experienced the quick transition of his polis from a small city-state to a leading political and military force to be reckoned with throughout the Greek world. The inscription on his gravestone at Gela, Italy, commemorates his military achievements against the Persians, but makes no mention on his enormous theatrical renown. His plays (...) were so respected by the Athenians that after his death, his were the only tragedies allowed to be restaged in subsequent competitions. And yet Aeschylus, when time came to describe himself and the work of his lifetime, mentioned exclusively his contribution in the fight against the Persian Empire as an Athenian. Triggered by the poet’s narrative on his most memorable moment of his life, the present paper seeks to shed some light on the Athenian political identity, emerged during and soon after the Persian Wars, which not only derived from the newly-established democratic constitution of the late sixth century, but also supported it. Aeschylus’ epigram as well as some particular plays of his, narrates the confidence, the solidarity and the feeling of equality the Athenian citizens shared in regards to the defence of freedom of their polis as well as of all Greece, which came above anything else in their life, meaning above noble lineage and wealth. The gravestone of the poet stresses, in other words, how it felt like for an Athenian to live during the emergence of the very first Democracy that progressively supported the claim of Athens to become a ruler in the Aegean, by constructing its naval "Empire", ideologically upon the commemoration of the victory of the Athenian Democracy against the tyranny of Persia at Marathon and Salamis. (shrink)

Xenocrates of Athens was a sculptor and theoretician of the 3rd cen. B.C., whose now lost writings were used as basic sources by Pliny the Elder in his 34th and 35th Books of Natural History, about Sculpture and Painting respectively. It is strongly believed that the progressive model of the development of art in both books has Xenocratian origins: influenced by the tradition of Democritus, Xenocrates had explained the evolution of art as a process of resolution of artistic problems. His (...) narrative was, though, a descriptive one without a theoretical or philosophical background. A similar case had prevailed in the Historiography of Art for many centuries, up to the beginnings of the 20th cen., when the rise of Philosophical Hermeneutics changed the picture. Art Historians began to create theories and methods trying for the first time to explain at a theoretical level the phenomena both of the development of art and of the capability of later perceivers to understand previous artworks and their changes through time. Ernst Gombrich’s theory that combines modern and postmodern ideas is to be understood as influenced both by the Xenocratian idea that there is always an innovative person who first overcomes traditional methods triggering the progress of art’s development and by the Popperian notion of “trial and error” as the main schema for the development of science. (shrink)

(2012). Speusippus on Cognitive Sense Perception: Sextus Empiricus M 7.145‐6. British Journal for the History of Philosophy: Vol. 20, No. 6, pp. 1183-1193. doi: 10.1080/09608788.2012.731246.

Journal Name: Semiotica - Journal of the International Association for Semiotic Studies / Revue de l'Association Internationale de Sémiotique Volume: 2013 Issue: 196 Pages: 381-390.