This is a unique, groundbreaking study in the history of philosophy, combining leading men and women philosophers across 2600 years of Western philosophy, covering key foundational topics, including epistemology, metaphysics, and ethics. Introductory essays, primary source readings, and commentaries comprise each chapter to offer a rich and accessible introduction to and evaluation of these vital philosophical contributions. A helpful appendix canvasses an extraordinary number of women philosophers throughout history for further discovery and study.

In a recent article, Edward Saraydar takes economists and economic historians to task for equating productivity and efficiency in comparative economic analysis. Although I found his thesis interesting, I was a bit surprised to see selected remarks from my article on firm size in nineteenth-century France used to frame his criticism of productivity comparisons as a means of making prescriptive statements. The passages selected may mislead the reader as to the nature of my arguments. Let me quote Saraydar on (...) this: … I argue that … the problem with equating productivity with efficiency is that from the neoclassical standpoint this strongly suggests a prescriptive view - a view that things should be or should have been different - and thereby frees the analyst from the need to justify the utility costs that might be or might have been required to make things different. Thus, in the French industrialization debate, for example, Nye points out that evidence that smaller family firms were less productive would support the conclusion “that nineteenth-century French firms were too small and that consequently French industry suffered from inefficiency”. Suppose the evidence to which Nye refers to existed. [My emphasis] Distributive considerations aside, in neoclassical economics a more Pareto-efficient state by its very nature is to be preferred to a less efficient one. Therefore, the implication is that family firms should have been larger and more productive. However, suppose also that the plethora of small family firms in nineteenth-century France, in fact, constituted a longstanding, widely accepted, socially imbedded institution. Clearly, the traditionalist thought-experiment and conclusion would ignore the potential costs in utility or satisfaction to owners of factors of production, a utility loss that may well have been required to make the “more efficient.” transformation to a relatively few large-scale industrial firms. That potential utility loss cannot be ignored and should be part of the analysis. (shrink)

The literature of comparative economics as well as economic history is replete with references to productivity differences as reflecting relative efficiency in production. In socialist economics, for example, the longevity of the relative-productivity/relative-efficiency theme is apparent from Abram Bergson's early survey where, commenting on a productivity debate that had already been going on for over twenty years, he identified “the only issue outstanding” as the question “which is more efficient, socialism or capitalism?” The issue has continued to be addressed vigorously (...) since then, and it is still outstanding. Again, in European economic history, John Nye recently pointed out that relative efficiency as reflected in relative productivity has been part and parcel of the postwar debate on French industrialization: the view that less productive and, therefore, “inefficient” family firms led to French “backwardness” in production. (shrink)

Without Good Reason offers a clear critical account of the debate in philosophy and cognitive science about whether humans are rational. Various experiments performed over the last several decades have been interpreted as showing that humans are irrational; certain philosophers, on the other hand, have argued that it is a conceptual truth that humans must be rational. Edward Stein concludes that the question of human rationality should be answered not conceptually but empirically: the resources of a fully developed cognitive (...) science need to be used not only to answer this question but generally in investigations of the nature of human knowledge and understanding. (shrink)

Could anything provide a philosophically convincing mark of the mental in simple organisms (Lloyd 1984)? Individual organisms’ capacities to modify behavior adaptively as a result of past encounters with the environment might mark the first step in the phylogeny of minds. The simplest examples of mental representation are likely to be found in the simplest forms of animal learning.The most scientifically rigorous test case of “bottom- up” strategies in cognitive neuroscience is provided by current studies of the cellular and molecular (...) biology of associative learning in higher invertebrates, but particularly gastropod molluscs, snails or slugs (Quinn 1984). For the relevant neurobiological research community (Farley and Alkon 1985; Hawkins, Clark, and Kandel 1986), “Bottom-up” does not just mean letting one’s study of the properties of the nervous system control one’s analyses of animal behavior or cognition. (shrink)

I present an intractable puzzle for the currently popular view that belief is weak—the view that expressions like ‘S believes p’ ascribe to S a doxastic attitude towards p that is rationally compatible with low credence that p. The puzzle concerns issues that arise on considering beliefs in conditionals. I show that proponents of weak belief either cannot consistently apply their preferred methodology when accommodating beliefs in conditionals, or they must deny that beliefs in conditionals can be used in reasoning.

The relation between ex falso and disjunctive syllogism, or even the justification of ex falso based on disjunctive syllogism, is an old topic in the history of logic. This old topic reappears in contemporary logic since the introduction of minimal logic by Johansson. The disjunctive syllogism seems to be part of our general non-problematic inferential practices and superficially it does not seem to be related to or to depend on our acceptance of the frequently disputable ex falso rule. We know (...) that the acceptance of the ex falso is a sufficient condition for the acceptance of the disjunctive syllogism, but the interesting question is: is the ex falso a necessary condition for the acceptance of the disjunctive syllogism? The aim of the present paper is to discuss some possible ways to define systems that combines the preservation of the disjunctive syllogism with the rejection of the ex falso. (shrink)

Each year, over 200 million people are infected with the malaria parasite, nearly half a million of whom succumb to the disease. Emerging genetic technologies could, in theory, eliminate the burden of malaria throughout the world by intentionally eradicating the mosquitoes that transmit the disease. In this paper, we offer an ethical examination of the intentional eradication of Anopheles gambiae, the main malaria vector of sub-Saharan Africa. In our evaluation, we focus on two main considerations: the benefit of alleviating the (...) malaria burden, and the loss of value that would accompany the eradication of the species. We outline a typology of the different ways in which species are valued or could be valuable, then use that typology to appraise the value of the species in question. We argue that Anopheles gambiae has minor (and redundant) instrumental value, little final subjective value and no objective final value. (shrink)

Previous research has suggested that an effective strategy for debiasing judgments is to have participants "consider the opposite." The present research proposes that considering any plausible alternative outcome for an event, not just the opposite outcome, leads participants to simulate multiple alternatives, resulting in debiased judgments. Three experiments tested this hypothesis using an explanation task paradigm. Participants in all studies were asked to explain either 1 hypothetical outcome (single explanation conditions) or 2 hypothetical outcomes (multiple explanation conditions) to an event; (...) after the explanation task, participants made likelihood judgments. The results of Studies 1 and 2 indicated that debiasing occurred in all multiple explanation conditions, including those that did not involve the opposite outcome. Furthermore, the findings indicated that debiased judgments resulted from participants' spontaneous consideration of additional alternatives in making their likelihood judgments. The results of Study 3 also identified the perceived plausibility of the explained alternative as an important moderating variable in debiasing. (shrink)

A key component of research on human sentence processing is to characterize the processing difficulty associated with the comprehension of words in context. Models that explain and predict this difficulty can be broadly divided into two kinds, expectation‐based and memory‐based. In this work, we present a new model of incremental sentence processing difficulty that unifies and extends key features of both kinds of models. Our model, lossy‐context surprisal, holds that the processing difficulty at a word in context is proportional to (...) the surprisal of the word given a lossy memory representation of the context—that is, a memory representation that does not contain complete information about previous words. We show that this model provides an intuitive explanation for an outstanding puzzle involving interactions of memory and expectations: language‐dependent structural forgetting, where the effects of memory on sentence processing appear to be moderated by language statistics. Furthermore, we demonstrate that dependency locality effects, a signature prediction of memory‐based theories, can be derived from lossy‐context surprisal as a special case of a novel, more general principle called information locality. (shrink)

Edward S. Casey provides a thorough description of the varieties of human memory, including recognizing and reminding, reminiscing and commemorating, body memory and place memory. The preface to the new edition extends the scope of the original text to include issues of collective memory, forgetting, and traumatic memory, and aligns this book with Casey's newest work on place and space. This ambitious study demonstrates that nothing in our lives is unaffected by remembering.

The Dialectical Forge identifies dialectical disputation as a primary formative dynamic in the evolution of pre-modern Islamic legal systems, promoting dialectic from relative obscurity to a more appropriate position at the forefront of Islamic legal studies. The author introduces and develops a dialectics-based analytical method for the study of pre-modern Islamic legal argumentation, examines parallels and divergences between Aristotelian dialectic and early juridical jadal-theory, and proposes a multi-component paradigm—the Dialectical Forge Model—to account for the power of jadal in shaping Islamic (...) law and legal theory.In addition to overviews of current evolutionary narratives for Islamic legal theory and dialectic, and expositions on key texts, this work shines an analytical light upon the considerably sophisticated “proto-system” of juridical dialectical teaching and practice evident in Islam’s second century, several generations before the first “full-system” treatises of legal and dialectical theory were composed. This proto-system is revealed from analyses of dialectical sequences in the 2nd/8th century Kitāb Ikhtilāf al-ʿIrāqiyyīn / ʿIrāqiyyayn through a lens molded from 5th/11th century jadal-theory treatises. Specific features thus uncovered inform the elaboration of a Dialectical Forge Model, whose more general components and functions are explored in closing chapters. (shrink)

Are there circumstances under which scientists and engineers doing their ordinary jobs can be thought of as participants in a social movement? The technoscientists analyzed in this article are at the forefront of a new way of doing chemistry; they are attempting to redesign chemical products and synthesis pathways to significantly reduce health effects and environmental damage from industrial chemicals. Green chemistry practitioners and entrepreneurs now constitute a small minority of chemists and chemical engineers in the university, government, and corporate (...) sectors, but the innovators gradually are institutionalizing their efforts and winning converts. Drawing on concepts from social movement theory, the authors argue that examining green chemistry as a social movement sheds light on the intentional social organization of emerging scientific and engineering disciplines, advances thinking about the role of expertise in social change, and uncovers a possible pathway toward reconstructing chemical technologies on a more environmentally sustainable basis. The article closes with questions about potential coalitions among green chemists and engineers, regulators, and activist sectors of civil society. (shrink)

Encouraging people to consider multiple alternatives appears to be a useful debiasing technique for reducing many biases (explanation, hindsight, and overconfidence), if the generation of alternatives is experienced as easy. The present research tests whether these alternative generation procedures induce a mental simulation mind-set (cf. Galinsky & Moskowitz, 2000), such that debiasing in one domain transfers to debias judgments in unrelated domains. The results indeed demonstrated that easy alternative generation tasks not only debiased judgments in the same domain but also (...) generalized to debias judgments in unrelated domains, provided that participants were low in the need for structure. The alternative generation tasks (even when they were easy to perform) showed no evidence of activating a mental simulation mind-set in individuals high in need for structure, as these individuals displayed no transfer effects. Implications of the results for understanding the role of the need for structure, ease of generation, and mental simulation mind-set activation for debiasing are discussed. (shrink)

Drawing on his own experiences of imagining, Edward S. Casey describes the essential forms that imagination assumes in everyday life. In a detailed analysis of the fundamental features of all imaginative experience, Casey shows imagining to be eidetically distinct from perceiving and defines it as a radically autonomous act, involving a characteristic freedom of mind. A new preface places Imagining within the context of current issues in philosophy and psychology.

Two studies examined the allegiance bias – the rendering of biased predictions by individuals who are psychologically invested in a desired outcome. In Study 1, fans of either Notre Dame or University of Miami college football read information about an upcoming game between the two teams and then explained a hypothetical victory either by Notre Dame or Miami. Although explaining a hypothetical victory biased the judgments of controls (i.e., fans of neither team) in the direction of the team explained, the (...) judgments of Notre Dame and Miami fans favored their team in every explanation condition. In addition, fans exhibited biased recall for facts favoring their own teams and this biased recall predicted fans’ judgments regarding the upcoming game. Study 2 attempted to specify a debiasing technique that might attenuate the allegiance bias. Indiana University basketball fans described what they thought might happen in an upcoming game between Indiana and the University of Michigan while anticipating having a discussion about the game (i.e., predecisional accountability) with either an Indiana fan, a Michigan fan, or a fan of unknown allegiance. As predicted, anticipating a discussion with a fan of unknown allegiance engendered game predictions that were the least biased in favor of an Indiana victory. Implications for social explanation and prediction research are discussed. (shrink)

As the sustained and devastating extent of the coronavirus disease 2019 pandemic becomes apparent, a key focus of public scrutiny in the UK has centred on the novel legal and regulatory measures introduced in response to the virus. When those measures were first implemented in March 2020 by the UK Government, it was thought that human rights obligations would limit excesses of governmental action and that the public had more to fear from unwarranted intrusion into civil liberties. However, within the (...) first year of the pandemic’s devastation in the UK, a different picture has emerged: rather than through action, it is governmentalinactionthat has given rise to greater human rights concerns. The UK Government has been roundly criticized for its inadequate response, including missteps in decision-making, delayed implementation and poor enforcement of lockdown measures, abandonment of testing, shortages of critical resources and inadequate test and trace methods. In this article, we analyse the UK Government’s missteps and compare them with published international guidance; we also contrast the UK’s decisions with those taken by several other countries to understand how its actions and inactions have contributed to unfavourable outcomes. Using an analytical perspective that demonstrates how human rights are both a protection from the power of the state and a requirement that governmental powers are used to protect the lives, health and wellbeing of citizens, we argue that the UK Government’s failure to exercise their powers competently allowed the virus to spread without ensuring the country had the means to manage a high case load. This abject failure has led to one of the highest rates of deaths per capita worldwide. We offer several lessons that can be learnt from this unfortunate, but preventable, situation. (shrink)

Scandinavia is routinely cited as a global leader in corporate social responsibility and sustainability. In this article, we explore the foundation for this claim while also exploring potential contributing factors. We consider the deep-seated traditions of stakeholder engagement across Scandinavia including the claim that the recent concept of “creating shared value” has Scandinavian origins, institutional and cultural factors that encourage strong CSR and sustainability performances, and the recent phenomenon of movement from implicit to explicit CSR in a Scandinavian context and (...) what this may entail. In sum, we depict the state of the art in CSR and sustainability in Scandinavia. We intend for this to serve as a basis to help establish a globally recognized research paradigm dedicated to considering CSR and sustainability in a Scandinavian context. (shrink)

About forty years ago, when print media were still in their ascendancy, Marshall McLuhan argued that all media are extensions of the senses and that the rational view of the world associated with print is being replaced by a world-view associated with electronic media that stresses feelings and emotions. In 2003 researchers from the School of Information Management Sciences at Berkeley estimated that five exabytes of information had been generated in the previous year, equivalent to 37,000 times the holdings of (...) the Library of Congress and that 92.00% of this was on magnetic media, mostly hard disks, while only 0.01% was in print. This SIMS estimate could be wrong by several orders of magnitude and it would still be clear that the era of the printed word is waning rapidly. We are well-advised to pay attention to McLuhan’s suggestionthat electronic media change how we think and how we feel.Sense of place and virtual reality are both inextricably caught up in this cultural-technological upheaval. I have written about the concept of ‘place’ from a phenomenological perspective for many years and have achieved a reasonable understanding of its subtleties, but I have a limited knowledge of digital virtual reality and its technical attributes. Nevertheless, it seems to me that a mutual interaction is at work between what might be called ‘real’ place and virtual places, that digital virtual reality shares characteristics with other electronic media and that our experiences of real places are being changed those same media. This essay explores these issues particularlyfrom the perspective of the distinction between spirit of place and sense of place. (shrink)

Topics include sources of schematic effects on memory; the M. Ross and M. Conway model; E. R. Hirt's model of reconstructive memory; and moderators of the relative weighting of expectancy vs memory trace.

This paper examines the ethics of the Australian business community’s responses to the phenomenon of modern slavery. Engaging a critical discourse approach, we draw upon a data set of submissions by businesses and business representatives to the Australian government’s Joint Standing Committee on Foreign Affairs, Defence and Trade ‘Parliamentary Inquiry into Establishing a Modern Slavery Act in Australia’—which preceded the signing into law of Australia’s Modern Slavery Act 2018—to examine the business community’s discursive construction in their submissions of the ethical–political (...) concept of freedom. The paper shows how the concept of freedom was employed by Australian business in a manner that privileged their own subject status and advocated for legislation with minimal burden. Relating this contemporary case to a longer historical context, we show how Australian business responses towards modern slavery map onto liberal and neoliberal ethics in which the freedom of the propertied takes precedent over that of the property-less. Further, we show discursive similarities in the arguments presented by modern Australian businesses and certain historical efforts by members of the business community to privilege commercial freedoms in responses to 18th and 19th Century abolitionist movements. Overall, our research makes two important contributions: first, it highlights the value of a critical discourse lens in business ethics research to show how business and other stakeholders in the field construct and shape their own and other’s ethically-laden understanding of reality; and second, it presents a case for considerable scepticism about the motivation of business to employ the freedoms made available to it under neo/liberal discourse to confront a key human rights challenge. (shrink)

In this powerful new study Edward Baring sheds fresh light on Jacques Derrida, one of the most influential yet controversial intellectuals of the twentieth century. Reading Derrida from a historical perspective and drawing on new archival sources, The Young Derrida and French Philosophy shows how Derrida's thought arose in the closely contested space of post-war French intellectual life, developing in response to Sartrian existentialism, religious philosophy and the structuralism that found its base at the École Normale Supe;rieure. In a (...) history of the philosophical movements and academic institutions of post-war France, Baring paints a portrait of a community caught between humanism and anti-humanism, providing a radically new interpretation of the genesis of deconstruction and of one of the most vibrant intellectual moments of modern times. (shrink)

The United States has recently made significant and positive civil rights gains for LGB people, including expanded recognition of marriages between people of the same sex. Among the central tropes that have emerged in the struggle for the rights of LGB people are that they are “born that way,” that sexual orientations cannot change, and that one's sexual orientation is not affected by choice. Writer Andrew Sullivan put it this way: “[H]omosexuality is an essentially involuntary condition that can neither be (...) denied nor permanently repressed.… [S]o long as homosexual adults as citizens insist on the involuntary nature of their condition, it becomes politically impossible to deny or ignore the fact of homosexuality.… [The strategy for obtaining LGB rights is to] seek full public equality for those who, through no fault of their own, happen to be homosexual.”This idea of linking LGB rights to empirical claims about sexual orientations has become so central that casting doubt on these claims is, in many circles, tantamount to opposing LGB rights. Nonetheless, claims about innateness, immutability, and lack of choice about sexual orientation should not be the primary basis for LGB rights. (shrink)

Formulations of Anselm’s ontological argument have been the subject of a number of recent studies. We examine these studies in light of Anselm’s text and (a) respond to criticisms that have surfaced in reaction to our earlier representations of the argument, (b) identify and defend a more refined representation of Anselm’s argument on the basis of new research, and (c) compare our representation of the argument, which analyzes that than which none greater can be conceived as a definite description, to (...) a representation that analyzes it as an arbitrary name. (shrink)

This collection of papers, celebrating the contributions of Swedish logician Dag Prawitz to Proof Theory, has been assembled from those presented at the Natural Deduction conference organized in Rio de Janeiro to honour his seminal research. Dag Prawitz’s work forms the basis of intuitionistic type theory and his inversion principle constitutes the foundation of most modern accounts of proof-theoretic semantics in Logic, Linguistics and Theoretical Computer Science. The range of contributions includes material on the extension of natural deduction with higher-order (...) rules, as opposed to higher-order connectives, and a paper discussing the application of natural deduction rules to dealing with equality in predicate calculus. The volume continues with a key chapter summarizing work on the extension of the Curry-Howard isomorphism, via methods of category theory that have been successfully applied to linear logic, as well as many other contributions from highly regarded authorities. With an illustrious group of contributors addressing a wealth of topics and applications, this volume is a valuable addition to the libraries of academics in the multiple disciplines whose development has been given added scope by the methodologies supplied by natural deduction. The volume is representative of the rich and varied directions that Prawitz work has inspired in the area of natural deduction. (shrink)

Fertilization triggers cytoplasmic movements in the frog egg that lead in mysterious ways to the stabilization of β‐catenin on the dorsal side of the embryo. The novel Huluwa (Hwa) transmembrane protein, identified in China, is translated specifically in the dorsal side, acting as an egg cytoplasmic determinant essential for β‐catenin stabilization. The Wnt signaling pathway requires macropinocytosis and the sequestration inside multivesicular bodies (MVBs, the precursors of endolysosomes) of Axin1 and Glycogen Synthase Kinase 3 (GSK3) that normally destroy β‐catenin. In (...) Xenopus, the Wnt‐like activity of GSK3 inhibitors and of Hwa mRNA can be blocked by brief treatment with inhibitors of membrane trafficking or lysosomes at the 32‐cell stage. In dorsal blastomeres, lysosomal cathepsin is activated and intriguing MVBs surrounded by electron dense vesicles are formed at the 64‐cell stage. We conclude that membrane trafficking and lysosomal activity are critically important for the earliest asymmetries in vertebrate embryonic development. (shrink)

The renowned occult scholar Arthur Edward Waite left no stone unturned when preparing this meticulously researched volume on the life and works of the French mystic Louis Claude de Saint-Martin. Drawing on contemporary biographies, correspondences, and all the source materials that were available to him at the time, he put together a biography and summary of Saint-MartinÍs work that is still unsurpassed to this day. This edition is presented with modernised typography and a new and expanded index.

Alexander Herzen was the most outstanding figure in the early period of the Russian revolutionary movement. Lenin claimed him as a forerunner of the Bolsheviks, and Soviet scholars have sought to establish his latent sympathy with Marxism. In the west on the other hand, he has been seen as a precursor of Solzhenitsyn, the personification of protest against all forms of oppression. Dr Acton provides a compelling intellectual biography. The focus is on the years between 1847 and 1863. Herzen's ideas (...) are set in the context of those political developments and dramatic private experiences that affected his outlook. His profound faith in human nature and in the inevitable triumph of socialism was undermined not only by the failure of the revolutions of 1848, but even more deeply by personal catastrophe - the discovery of the infidelity of his beautiful wife Natalie. This dual blow, Dr Acton shows, had a decisive impact upon Herzen's approach to Russian problems. It lay at the root of the ambivalent attitude he adopted towards peasant revolution in the critical period of Emancipation. (shrink)

I argue against the skeptical epistemological view exemplified by the Groarkes that “all theories of informal argument must face the regress problem.” It is true that in our theoretical representations of reasoning, infinite regresses of self-justification regularly and inadvertently arise with respect to each of the RSA criteria for argument cogency (the premises are to be relevant, sufficient, and acceptable). But they arise needlessly, by confusing an RSA criterion with argument content, usually premise material.

Heritable personality traits often predict fundamental philosophical disagreement. This conclusion is based on studies of more than 15,000 people sampled from diverse cultures and educational backgrounds, including verifiable experts. In this chapter, we review some of this research showing links between personality and philosophical bias in free will, intentional action, and ethics. Our discussion focuses on serious challenges that these philosophical biases pose (e.g., limits on the use of philosophical intuitions as evidence). We close with discussion of the Philosophical Personality (...) Argument and brief consideration of emerging projects in applied experimental philosophy. (shrink)

In this chapter, Said argues that in the case of the Palestinians and Israelis, histories and cultures are inextricably linked ‘contrapuntally’ in symbiotic rather than mutually exclusive terms. When this understanding of circumstances occurs, it no longer seems viable to eliminate the opposition because there will always be a tomorrow in which retribution will be demanded by those who feel that an injustice had been forced upon family members or previous generations. Said emphasizes the need to think about and resolve (...) two histories that have become interwoven, despite the fact that many have tried to define the other in contradictory terms. Part of arriving at a Just Peace entails recognizing a shared identity and common history even if this approach highlights differences. This might be a monumental task considering the trials and tribulations that have often come to pass in a conflict, but for Said, an ‘abridged memory’ is not an option that will lead to Just Peace. (shrink)

Until the time of Karl Marx and John Stuart Mill, philosophers generally held economics to be an integral element of moral philosophy. These days, the language of values—moral, aesthetic, and cognitive—dominates philosophic discourse, even though contemporary philosophers rarely hold economics to be integral to moral philosophy. Examining the thought of Friedrich Nietzsche and the art of Marcel Proust, Edward Andrew provides the first sustained critical analysis of values discourse, an analysis that deconstructs its content and its form.

This paper re-constructs Plato's ‘philosophy of geometry’ by arguing that he uses a geometrical method of hypothesis in his account of the cosmos’ generation in the Timaeus. Commentators on Plato's philosophy of mathematics often start from Aristotle's report in the Metaphysics that Plato admitted the existence of mathematical objects in-between ( metaxu) Forms and sensible particulars ( Meta. 1.6, 987b14–18). I argue, however, that Plato's interest in mathematics was centred on its methodological usefulness for philosophical inquiry, rather than on questions (...) of mathematical ontology. My key passage of interest is Timaeus’ account of the generation of the primary bodies in the cosmos, i.e. fire, air, water and earth ( Tim. 48b–c, 53b–56c). Timaeus explains the primary bodies’ origin by hypothesising two right-angled triangles as their starting-point ( arkhê) and describing their individual geometrical constitution. This hypothetical operation recalls the hypothetical method which Socrates introduces in the Meno (86e–87b), as well as the use of hypotheses by mathematicians which is described in the Republic (510b–c). Throughout the passage, Timaeus is focussed on explicating the bodies in terms of their formal structure, without however considering the ontological status of the triangles in relation to the physical world. (shrink)

Background Generally, there is unanimity about the value of community engagement in health-related research. There is also a growing tendency to view genetics and genomics research (GGR) as a special category of research, the conduct of which including community engagement (CE) as needing additional caution. One of the motivations of this study was to establish how differently if at all, we should think about CE in GGR. Aim To assess the perspectives of genetics and genomics researchers in Uganda on CE (...) in GGR. Method A cross-sectional qualitative study was conducted at Makerere University and Uganda Virus Research Institute. Twenty-five individuals participated, the majority being male (sixteen). Participants included nineteen genetics and genomics researchers (researchers and research coordinators), two CE officers, three nurses and one nursing counsellor. Data were collected using in-depth interviews and analyzed in a thematic manner using NVivo version 12 Plus. Study findings Thirteen of the respondents had conducted CE in their GGR in either a geographical and disease-specific community. Some respondents said CE principles are the same and there is no need for special consideration for CE in GGR. Others gave ethical issues in GGR that require special consideration for CE in such research and these were categorized into six themes: GGR is new to communities, Difficulty in communicating GGR by the researchers, Genes are shared in communities, Cultural sensitivities against GGR, Community attitude toward GGR, Some GGR studies take long to end, and Negotiation of research benefits. Special considerations for CE when conducting GGR were suggested and categorized into seven themes: creating awareness of GGR in communities, obtaining both community acceptance and individual consent, CE team composition, involve communities in solving GGR challenges, prolong CE in some GGR, develop guidelines for CE in GGR, and legal considerations on GGR. Conclusion GGR was characterized by special issues that require special CE considerations for such research. (shrink)

Professional mediators have long possessed a skill set that is uniquely suited to facilitation of difficult conversations between and among individuals in emotionally charged situations. This skill set has increasingly been recognized as invaluable to the work of clinical ethics consultants as they navigate conflicts involving families, surrogates, and providers. Given widespread acknowledgment that communication difficulties lie at the root of many clinical ethics conflicts, mediation offers techniques to enhance communication between conflicting parties. This special section of The Journal of (...) Clinical Ethics focuses on core aspects of the mediation process designed for effective management of clinical conflict emanating from communication breakdowns, highly charged value conflicts, and instances of perceived disrespect. (shrink)

Abstract:A placebo is an intervention that is believed to lack specific pharmacological or physiological efficacy for a patient's condition. While placebo-controlled trials are considered the gold standard when it comes to researching and testing new pharmacological treatments, the use of placebos in clinical practice is more controversial. The focus of this case study is an undisclosed placebo trial used as an attempt to diagnose a patient's complex and unusual symptomology. In this case, the placebo was used not just as a (...) treatment, but as a diagnostic intervention in order to determine the best course of treatment for a patient. Could the deceptive use of a placebo be justified in clinical practice on the grounds of beneficence? (shrink)