Franchising in the business format sector accounted for approximately 35 percent of retail sales in the U.S. in 1991. Consequently, the franchising industry has a clear ethical responsibility to the public. At the same time, there exists an ethical obligation of the two major factors in the industry — the franchisor and the franchise — toward each other. Because the franchise agreement, which is the basis of the relationship, is originated by the franchisor, an asymmetrical distribution of power often exists, (...) resulting in opportunistic behavior by the franchisor. In other cases, questionable or unethical practices by franchisees likewise result in conflict. This paper examines some of the basic areas of the franchise relationship which result in conflict, and discusses the situation analysis in business format franchising, which shows promise for reduction of conflict and unethical behavior for the future. (shrink)

The origin of insulin‐expressing β‐cells in the adult mammalian pancreas is controversial. During normal tissue turnover and following injury, β‐cells may be replaced by duplication of existing β‐cells.1 However, an alternative source of β‐cells has recently been proposed based on neogenesis from a Ngn3‐positive population present in regenerating pancreatic ducts.2 The appearance of β‐cells from Ngn3‐positive progenitors is reminiscent of normal pancreas development, and Ngn3‐expressing cells isolated from regenerating pancreas can generate the full repertoire of endocrine phenotypes. The isolation and (...) characterisation of the equivalent human progenitors may represent a significant step forward in the hunt for a cure for diabetes. BioEssays 30:617–620, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Darwin proposed that evolutionary novelties are environmentally induced in organisms “constitutionally” sensitive to environmental change, with selection effective owing to the inheritance of constitutional responses. A molecular theory of inheritance, pangenesis , explained the cross‐generational transmission of environmentally induced traits, as required for evolution by natural selection. The twentieth‐century evolutionary synthesis featured mutation as the source of novelty, neglecting the role of environmental induction. But current knowledge of environmentally sensitive gene expression, combined with the idea of genetic accommodation of mutationally (...) and environmentally induced change, supports a revival of Darwin's original theory that is consistent with modern molecular and population genetics. †To contact the author, please write to: Smithsonian Tropical Research Institute, c/o Escuela de Biología, Universidad de Costa Rica, Costa Rica; e‐mail: [email protected]. (shrink)

Gottfried Wilhelm von Leibniz (1646-1716) has a prominent worldwide place in the history of scientific thought, from mathematics, logic, and physics to astronomy and engineering. In 2016, both his birth and death have been commemorated. Given the influence by Leibniz on Western sciences and philosophies and his polyhedric scientific activities, this special book chooses to focus on Leibniz's scientific works. In particular, we explore Leibniz's intellectual matrix and heritage within interdisciplinary fields, and present contributions from leading experts on the subject. (...) The book offers much-needed insights into the subject from scientific, historical, philosophical and nature of science perspectives. It also provides authoritative introductions to scholarly contributions, which are often dispersed in journals and books not easily accessible to every reader. Therefore, this volume also contains excellent chapters on topics which, generally speaking, have their place in any rounded science, history or philosophy topic. It provides an absorbing and significant read for historians, philosophers and scientists alike. Editors Raffaele Pisano is full professor at the Lille University, France. Michel Fichant is Emeritus professor at the Sorbonne University, France. Paolo Bussotti is senior lecturer-researcher at the Udine University, Italy. Agamenon R. E. Oliveira is full professor at the Federal University of Rio de Janeiro, Brazil. Foreword Eberhard Knobloch is Emeritus professor at the Berlin University of Technology, Germany. (shrink)

In view of the scope and scale of the latest scandals, e.g. Enron's maximum breaking bankruptcy, the re-discovery of ethics in business has received an impressive boost. By now even car salesmen have written ethics, a Code of Conduct, e.g. in the USA or Poland. But there is no clear aim of the role ethics obtains in organizational settings as we may show in some small cases of practical approaches to deal with ethics in organizations. We discuss how ethics is (...) the prerequisite to conduct any business and what advantages may be realized if a clear set of ethics is followed. We will discuss three practical examples. In cases of ethics-based values-added management of Siemens (Germany), Boeing (U.S.) and SAP (Germany) we explain the mechanisms of ethics in management to strengthen organizational success. We emphasize the importance of clear ethics-related communication processes in organizations. We explain the use of communication theories inside organizational processes to clarify communication about such an abstract topic as ethics. Finally, we point out how a management of ethical ideas and cultural values should be designed in business enterprises. (shrink)

First, the demonstration of Bell's theorem, i.e., of the nonlocal character of quantum theory, is spelled out using the EPR criterion of reality as premises and a gedankenexperiment involving two particles. Then, the EPR criterion is extended to include quantities predicted almostwith certainty, and Bell's theorem is demonstrated on these new premises. The same experiment is used but in conditions that become possible in real life, without the requirements of ideal efficiencies and zero background. Very high efficiencies and low background (...) are needed, but these requirements may be met in the future. (shrink)

For the last forty years our knowledge of the genealogy of the lords of Beirut from the Brisebarre family has been based on the research done by M. E. Nickerson, which was a true advance over earlier work on the same problem. Nickerson proposed the following succession of lords of Beirut.

Currently, electronic agents are being designed and implemented that, unprecedentedly, will be capable of performing legally binding actions. These advances necessitate a thorough treatment of their legal consequences. In our paper, we first demonstrate that electronic agents behave structurally similar to human agents. Then we study how declarations of intention stated by an electronic agent are related to ordinary declarations of intention given by natural persons or legal entities, and also how the actions of electronic agents in this respect have (...) to be classified under German law. We discuss four different approaches of classifying agent declarations. As one of these, we propose the concept of an electronic person (i.e., agents with limited liability), enrolment of agents into an agent register, and agent liability funds as means to serve the needs of all contracting parties. (shrink)

Patients suffering from chronic obstructive pulmonary diseases, frequently exhibit expiratory airflow limitation. We propose a mathematical model describing the mechanical behavior of the ventilated respiratory system. This model has to simulate applied positive end-expiratory pressure effects during expiration, a process used by clinicians to improve airflow. The proposed model consists of a nonlinear two-compartment system. One of the compartments represents the collapsible airways and mimics its dynamic compression, the other represents the lung and chest wall compartment. For all clinical conditions (...) tested, the mathematical model simulates the removal of expiratory airflow limitation at PEEP lower than 70–80% of intrinsic end-expiratory pressure, i.e. the end-expiratory alveolar pressure without PEEP. It also shows the presence of an optimal PEEP. The optimal PEEP contributes to decrease PAet from 7.4 ± 0.9 to 5.4 ± 0.9 hPa. This simplistic mathematical model gives a plausible explanation of the expiratory airflow limitation removal with PEEP and a rationale to the practice of PEEP application to airflow limited patients. (shrink)

In this article we establish the existence of a number of new orbits in the automorphism group of the computably enumerable sets. The degree theoretical aspects of these orbits also are examined.

In lieu of an abstract, here is a brief excerpt of the content:Kant's Critique of Berkeley HENRY E. ALLISON THE CLAIMTHAT KANT'S IDEALISM,or at least certain strands of it, is essentially identical to that of Berkeley has a long and distinguished history. It was first voiced by several of Kant's contemporaries such as Mendelssohn, Herder, Hamann, Pistorius and Eberhard who attacked the alleged subjectivism of the Critique of Pure Reason. 1 This viewpoint found its sharpest contemporary expression in the (...) notorious Garve-Feder review to which Kant responded at length in the Prolegomena. In subsequent times it has been championed by Schopenhauer, and most nineteenth century German commentators on the relation between the two philosophers. 2 In addition, it has been, and continues to be, the prevailing view of the vast majority of British writers on Kant, including, with significant qualifications, Norman Kemp Smith. 3 This tradition continues despite the fact that Kant specifically, and in no uncertain terms, repudiated this identification in the Prolegomena and the second edition of the Critique. In both works he responds to the charges of subjectivism, and in so doing distinguishes his position from that of Berkeley, who in the eighteenth century was commonly regarded as a solipsist and denier of the "external world." 4 In contra-distinction to Kant's own critical or transcendental idealism, which explains the possibility of synthetic a priori knowledge within the realm of possible experience, Berkeley is characterized as a "dogmatic" or "visionary idealist." He is judged guilty of "degrading bodies to mere illusion" (B69), of regarding things in space as "merely imaginary entities" (B274), and of holding with all "genuine idealists" that: "all knowledge through the senses and experience is i Cf. Hans Vaihinger, Commentar zu Kant's Kritik der Reinen Vernunft (Stuttgart, Berlin, Leipzig, 1892), II, 494-505. Cf. Friederich Fredericks, Der Phainomenale Idealisraus Berkeley's und Kant's (Berlin, 1871); Robert Zimmerman, "Ober Kant's Widerlegung des Idealismus yon Berkeley" (Sitzungsberichte der Akademie der Wissenschaften, Vienna, Philox.-hist. Kl.), LXVIII (1871); Gustav Dieckert, tiber dos Verhiiltnis des Berkeleyschen ldealismus zu Kantischen Vernun]tkritik (Konitz, 1888). Tiffs is a consequence of the general British tendency to view Kant in phenomenalist terms. A typical recent example is found in P. F. Strawson, The Bounds of Sense (London, 1966). Kemp Smith in his Commentary to Kant's Critique o[ Pure Reason (2nd ed., rev., 1923) takes greaZ pains to distinguish between the subjectivist strand in Kant's thought, which is essentially identical to Berkeley's position, and the genuine critical doctrine which stands side by side with it in the text. 9 Cf. I-I.M. Bracken, The Early Reception of Berkeley's Materialism 1710-1733, rev. ed. (The Hague: Martinus Nijhoff, 1965). [43] 44 HISTORY OF PHILOSOPHY nothing but sheer illusion, and only in the ideas of pure understanding is there truth" (374). 5 One of the chief reasons for the continuation of the Kant-Berkeley tradition is that these, and similar statements about Berkeley, which we find in these works and in Kant's correspondenc e with Beck, have not been taken very seriously by Kant's critics. They are usually dismissed as obvious misinterpretations, due to Kant's ignorance of Berkeley's actual writings, and of his reliance upon distorted second and third hand accounts of Berkeley's thought such as is to be found in Beattie. Furthermore, this view is often supported by the philological reflection that Kant did not read English, and that Berkeley's writings were not yet available in German translation. 6 The philological argument, however, loses much of its force when we consider that there was indeed a German translation of Berkeley's Dialogues, which although apparently unknown to nineteenth century scholars, was readily accessible to Kant. This is to be found, together with a translation of Collier's Clavis Universalis and critical analyses, in a work by the professor of philosophy at Rostock, Johann Christian Eschenbach, entitled: Samlung der vornehmsten Schri[tsteller die die tFirklichkeit ihres eignen K~rpers und der ganzen Ki~rperwelt leugnen (Rostock, 1756). Furthermore, in addition to this work, which was probably known to Kant, there is Berkeley's important Latin work, De Motu (1721), as well as French translations of many of... (shrink)

Leibniz' remarkable understanding of Chinese culture was not merely the result of his own acumen, but also of the knowledgeable sources of information available to him through published works and personal correspondence. Most of the materials are preserved in the Niedersächsische Landesbibliothek Hannover. Working from the Systematischen Bandkatalog compiled by Daniel Eberhard Baring in 1720 shortly after Leibniz' death, it is possible to know with some accuracy which books were available for Leibniz' reference. This author has complied a list (...) of 78 such works, most of which were either written by or derived from Christian missionaries in China, of whom the Jesuits were the most prominent. While some of Leibniz' correspondents such as Andreas Müller of Berlin were sinological amateurs and enthusiasts, others such as the Jesuit Joachim Bouvet were learned men, living in intimate contact with the Chinese emperor in Peking. Their letters guaranteed that Leibniz' information on China was among the most accurate available in Europe at that time. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Das Medusenhaupt der Kritik, Kantstudien Ergänzungshefte by Manfred GawlinaHenry E. AllisonManfred Gawlina. Das Medusenhaupt der Kritik, Kantstudien Ergänzungshefte 128. Berlin-New York: Walter de Gruyter, 1996. Pp. ix + 345.This work is the first full scale study of the controversy between Kant and the Wolffian philosopher Johann August Eberhard. The controversy was launched by Eberhard’s publication in 1788 of the first part of the first volume of (...) the Philosophisches Magazin, a journal which he and a handful of associates created specifically as an organ for attacking the Kantian philosophy from the standpoint of Leibniz and Wolff. The central claim was that whatever is true in the Kantian philosophy is already contained in Leibniz, and where Kant differs from Leibniz (such as in the denial of knowledge of things in themselves or “true things”) he goes astray. Kant reacted strongly to this [End Page 632] critique, first in a pair of letters to Reinhold (May 12 and 19, 1789) and then in his own published response, with the sarcastic title: Über eine Entdeckung. nach der alle neue Kritik der reinen Vernunft durch eine ältere entbehrlich gemacht werden soll1 From Eberhard’s side the controversy continued through three more volumes of the Philosophisches Magazin (1790–92), and two volumes of its successor, Philosophisches Archiv (1792–95). Although Kant himself did not respond directly to these subsequent attacks, he contributed material to Johann Schulz for his review of the second volume of the Philosophisches Magazin.Gawlina analyzes the controversy at both the pragmatic and philosophical levels. The former includes a consideration of the motivations of the protagonists and the various strategies and tactics adopted in an attempt to convince the philosophical public of the correctness of their respective positions. Eberhard, for his part, was particularly concerned with the threat which the Critique, which Kant himself describes as the “Medusa head” (hence the title), posed to the survival of Leibnizian-style metaphysics, while Kant’s primary concern was with the misrepresentation of his own philosophy that he saw in Eberhard’s attack. At the philosophical level, the controversy is presented as a clash between two conflicting and ultimately irreconcilable philosophical paradigms: the first being the ontological orientation of Leibniz (defended by Eberhard) according to which pure (contradiction-free) thought mirrors being (this entails that logic has ontological significance), and the epistemological-transcendental orientation of Kant, according to which the fundamental questions concern the conditions of human knowledge and the justification of its claims. The author is well aware that there are epistemological elements in Leibniz and ontological ones in Kant (most notably the claims about space and time in the Transcendental Aesthetic), but he argues persuasively that these are grounded in the philosopher’s respective ontological and epistemological standpoints.This general thesis serves to illuminate virtually all of the main points of the controversy, including the question of why Eberhard refuses to admit either the significance or novelty of the analytic-synthetic distinction, while Kant insists on both. Of particular interest in this regard is the author’s discussion of the distinction between Schranken (limits) and Grenzen (boundaries), which Kant himself draws in the Prolegomena (§58). This distinction becomes relevant to the controversy because of Eberhard’s frequent appeal to the fact that Leibniz recognizes the Schranken of human knowledge as part of his attempt to show that Leibniz anticipated Kant in providing a “critique of pure reason.” As Gawlina notes, however, the limits of knowledge, as understood by Leibniz, are merely de facto constraints on the extent to which finite minds are capable of grasping things from the eternalistic perspective of God, whereas the boundaries insisted on by Kant are principled restrictions, grounded in the positive conditions of the possibility of cognition for finite knowers. [End Page 633]Although Gawlina thus clearly indicates the ways in which Eberhard misunderstood and misrepresented Kant’s position, he refuses to declare Kant the victor in the controversy. This is partly on historical and partly on philosophical grounds. Historically, the reason is that in spite of all of its limitations, Eberhard’s critique of Kant did succeed in raising questions among Kant’s followers regarding the coherence of the... (shrink)

Einführung : Was ist Leben?. -- 1. T., Grundlagen der Lebensethik. Theologische Lebensethik und säkulare Bioethik ; Grundlagen der Lebensethik aus philosophischer Sicht ; Grundlagen der Lebensethik aus theologischer Sicht ; Ethische Prinzipien der Lebensethik -- 2. T., Konkrete Problemfelder. Die Verantwortung für das eigene Leben : Gesundheit und Krankheit ; Ethische Probleme im Zusammenhang mit der Ausweitung diagnostischer Verfahren ; Ethische Probleme im Zusammenhang mit der Ausweitung therapeutischer Verfahren ; Ethische Probleme der biomedizinischen Forschung ; Die Verantwortung für das (...) fremde Leben : Abtreibung und Euthanasie ; Die menschliche Verantwortung für das tierische Leben -- Schlussbetrachtung : Christliche Grundhaltungen der Lebensethik. (shrink)

The Catholic University Of America, Philosophical Studies, V88.

In this paper, I develop a quasi-transcendental argument to justify Kant’s infamous claim “man is evil by nature.” The cornerstone of my reconstruction lies in drawing a systematic distinction between the seemingly identical concepts of “evil disposition” (böseGesinnung) and “propensity to evil” (Hang zumBösen). The former, I argue, Kant reserves to describe the fundamental moral outlook of a single individual; the latter, the moral orientation of the whole species. Moreover, the appellative “evil” ranges over two different types of moral failure: (...) while an “evil disposition” is a failure to realize the good (i.e., to adopt the motive of duty as limiting condition for all one’s desires), an “evil propensity” is a failure to realize the highest good (i.e., to engage in the collective project of transforming the legal order into an ethical community). This correlation between units of moral analysis and types of obligation suggests a way to offer a deduction of the universal propensity on behalf of Kant. It consists in tracing the source of radical evil to the same subjective necessity that gives rise to the doctrine of the highest good. For, at the basis of Kant’s two doctrines lies the same natural dialectic between happiness and morality. While the highest good brings about the critically acceptable resolution of this dialectic, the propensity to evil perpetuates and aggravates it. Instead of connecting happiness and morality in an objective relation, the human will subordinate morality to the pursuit of happiness according to the subjective order of association. If this reading is correct, it would explain why prior attempts at a transcendental deduction have failed: interpreters have looked for the key to the deduction in the body of Kant’s text, where it is not to be found, for it is tucked, instead, in the Preface to the first edition. (shrink)

This article begins by asking if the project to write a philosophical novel is not inherently flawed; it would seem that the novelist must either write an ambiguous text, which would not create a strong enough argument to count as philosophy, or she must write a text with a clear argument, which would not be ambiguous enough to count as good fiction. The only other option available would be to exemplify a preexisting abstract philosophical system in the concrete literary world. (...) To move beyond such an impasse, this article turns to the work of Simone de Beauvoir. Beauvoir's unique aesthetic theory in “Literature and Metaphysics” envisions philosophy as an integral part of the literary text and sees the novel not as an argument but as something called a “philosophical appeal”. In her first novel, She Came to Stay, such a concept of the philosophical novel allows Beauvoir to make an original contribution to the philosophical tradition—one in which Beauvoir rethinks the problem of solipsism—while still creating a stunning literary work. A study of the theory and the novel together thus provides a solid understanding of what philosophers stand to gain from the philosophical novel. (shrink)

This article begins by asking if the project to write a philosophical novel is not inherently flawed; it would seem that the novelist must either write an ambiguous text, which would not create a strong enough argument to count as philosophy, or she must write a text with a clear argument, which would not be ambiguous enough to count as good fiction. The only other option available would be to exemplify a preexisting abstract philosophical system in the concrete literary world. (...) To move beyond such an impasse, this article turns to the work of Simone de Beauvoir. Beauvoir's unique aesthetic theory in "Literature and Metaphysics" envisions philosophy as an integral part of the literary text and sees the novel not as an argument but as something called a "philosophical appeal" (Beauvoir 2004b). In her first novel, She Came to Stay, such a concept of the philosophical novel allows Beauvoir to make an original contribution to the philosophical tradition—one in which Beauvoir rethinks the problem of solipsism—while still creating a stunning literary work (Beauvoir 1954). A study of the theory and the novel together thus provides a solid understanding of what philosophers stand to gain from the philosophical novel. (shrink)